Medicine and Health Sciences Commons^™

Validity Of Digital Cephalometric Tracing: A Systematic Review, Alia Chaudhry, Frank W. Licari, Shankargouda Patil

Annual Research Symposium

Aim of this systematic review was to assess the accuracy of digital cephalometric tracing with manual hand tracing.

Investigating Optimal Laboratory Growth Conditions Of Gracilibacillus Halotolerans In Media Supplemented With Salt, Isaac Young

Annual Research Symposium

As interest continues to grow in the field of persister cells and their morphology, there arises an ever-evolving desire to further understand specific strains of bacteria that exemplify the qualities of seemingly anomalous survival regardless of anti-bacterial treatment. In the case of the Gracilibacillus halotolerans, a halotolerant extremophile extracted from the Great Salt Lake with known persistent characteristics, uncovering its optimal growth conditions was essential for future investigations. Identifying the optimal salinity for the growth of G. halotolerans will allow us to standardize our growth methods, uncover several mechanisms of saline tolerance, and add to future investigations of persistence with …

Analysis Of Adolescent Malnutrition On Oral Health: A Systematic Review, Amy Blazejewski

Annual Research Symposium

This review aimed to explore the relationship between malnutrition and oral health in adolescents.

A literature search in PubMed, Dentistry & Oral Sciences Source, Scopus, and Web of Science was conducted on September 13th, 2023. Peer-reviewed articles written in English and published from 2013 containing information on the negative impact of adolescent malnutrition on oral health were considered eligible for review. From the 594 studies obtained from the literature search, 88 studies were included.

Evidence Of Prostate Cancer Progression In Transgender Women After Hormone Replacement Therapy - Scoping Review Protocol, Emily Nelson

Annual Research Symposium

This scoping review aims to determine the extent and quality of evidence regarding prostate cancer progression outcomes in transgender women who have undergone hormone replacement therapy. Notably, transgender females undergoing hormone replacement therapy as a component of the gender affirmation treatment commonly have their prostate, rendering them vulnerable to developing prostate cancer. There is no current agreement about the likelihood of transgender women developing prostate cancer or the impact of hormone replacement therapy on oncogenic molecular pathways. Unfortunately, due to a lack of scientific data and inadequate trust and awareness in the medical community, transgender women are often not provided …

Comparative Analysis Of Denture Cleanser Effects On Surface Roughness:Traditional Vs. 3d-Printed Resin Bases – A Systematic Review, Taroniar Sevathas, Shilpa Bhandi, Kamran H. Awan, Frank W. Licari, Shankargouda Patil

Annual Research Symposium

This systematic review aimed to assess the effect of denture cleansers on the surface roughness of 3D-printed denture base resins in comparison to conventionally manufactured counterparts.

Evaluating The Oral Health-Related Quality Of Life Among Dental Patients In South India - A Descriptive Study, Dheekshitha P K, Sudeep C B Dr., Sunil P M Dr., Suji M Dr.

Annual Research Symposium

This study aims to evaluate the oral health-related quality of life among dental patients in South India.

Exploring The Interplay Between Alzheimer's Disease And Periodontitis: Insights From Clinical Data And Inflammatory Biomarkers, Sandra Arun

Annual Research Symposium

Alzheimer's disease, a complex neurodegenerative disorder marked by cognitive decline, may have a intriguing link with periodontitis—a chronic inflammatory oral condition. This study investigates the literature evidence regarding the association between Alzheimer's disease and periodontitis. Our research aims to determine if individuals with periodontitis face an elevated risk of Alzheimer's and if shared inflammatory pathways underlie this association.

Evaluating Pi Angle Efficacy Against Established Cephalometric Angular Parameters, Sumit Bohra

Annual Research Symposium

Cephalometrics is a cornerstone of orthodontic diagnosis. Numerous angularmeasurements are used to assess the anteroposterior jaw relation include the ANB angle, Betaangle, Yen angle, and W angle. However, these have limitations, leading to the development of thePi angle. Our study aimed to evaluate the predictability of the Pi angle in a South Indian populationand compare it with other established antero-posterior dysplasia indicators such as the ANB angle,W angle, Yen angle, and Beta angle. This comparison is crucial for determining the most accuratemethod for assessing sagittal skeletal discrepancies.

Relationship Between Periodontal Disease And Coronary Heart Disease: A Bibliometric Analysis, Xiaowen Bo, Wenpeng Song

Annual Research Symposium

Periodontal disease (PD) and coronary heart disease (CHD) are both prevalent diseases worldwide and cause patients physical and mental suffering and a global burden. Recent studies have suggested a link between PD and CHD, but there is less research in this field from the perspective of bibliometrics. This study aimed to quantitatively analyze the literature on PD and CHD to summarize intellectual bases, research hotspots, and emerging trends and pave the way for future research.

Analysis Of Total Lip Score System And Total Groove Score For Gender Identification: A Cross Sectional Study, Abdullah Alqarni, Jagadish Hosmani, Abdullah Alqahtani, Nasser Alhamid, Abdullah Almathami

Annual Research Symposium

Endless ink and pixel space have been spent to validate the use of cheiloscopy classification systems in the field of identification. It is becoming evident that lip-print patterns may provide indications about an individual's gender, race, occupation, habits, blood type, and paternity. Over the course of time, much data has been collected on a substantial population in this field. In the present study, we strive to see how well a noble total lip scoring system (TLS) works in identifying a person's gender among College of Dentistry students. We also quantified the total groove score (TGS) and compared it with each …

Deciphering Psilocybin: Cytotoxicity, Anti-Inflammatory Effects, And Mechanistic Insights, Salma Laabi, Claire Lemmon, Callie Vogel, Mariana Chacon, Victor M. Jimenez

Annual Research Symposium

A decade of clinical research indicates psilocybin's effectiveness in treating various neuropsychiatric disorders, such as depression and substance abuse. The correlation between increased pro-inflammatory cytokines and the severity of neuropsychiatric symptoms, along with the known anti-inflammatory potential of some psychedelics, suggests an immunomodulatory role for psilocybin. This study aims to understand psilocybin's mechanism of action by investigating the cytotoxic and immunomodulatory effects of psilocybin and psilocin on both resting and LPS-activated RAW 264.7 murine macrophages.

Role Of Mumio In Periodontal Wound Healing–An In Vitro Study On Human Pdl Cells, Jagadish Hosmani, Abdullah Alqarni, Abdullah Alqahtani, Nasser Alhamid

Annual Research Symposium

Mumio, used in ancient medicine for almost 4000 years, is the gold standard of traditional medicine. Mumio, a tar-like compound made from rock dissolved minerals and degraded organic matter, takes a century to form. Dibenzo-alpha-pyrones, humic acid, and fulvic acid are important in Mumio, which includes 60–80% humus, benzoic acid, fatty acids, ichthyol, ellagic acid, resin, triterpenes, sterol, aromatic carboxylic acids, bioactive 3,4-benzokoumarins, amino acids, phenol Active chemicals improve Mumio's antioxidant effects. Despite its anti-ulcerogenic, anti-inflammatory, antioxidant, immunomodulatory, memory-enhancing, and anxiolytic characteristics, mumio has been studied rarely on oral tissues. The present study examined the cytotoxic, antioxidant, anti-inflammatory, and reparative …

Efficacy Of Concentrated Growth Factor Membrane Versus Collagen Membrane In Treating Gingival Recession, Shazneen Kandawalla

Annual Research Symposium

Creating a beautiful smile has always been a cornerstone of dental practice. Gingival recession, characterized by a downward shift of the gum line, causing uneven gum margins and an unattractive appearance.

The Vestibular Incision Subperiosteal Tunnel Access (VISTA) technique, introduced by Zadeh in 2011, offers an innovative solution for root coverage. Concentrated Growth Factor Membrane (CGF) further enhances dental repair.

Spatial Analysis Of Maxillary Central Incisors In Relation To The Nasopalatine Canal And Surrounding Alveolar Bone, Harnoor Dhillon

Annual Research Symposium

The use of mini-implants in orthodontics has enabled greater retraction of incisors than previously achievable. This change underscores the need to understand how incisors relate to the alveolar bone and nasopalatine canal. The varying labiolingual inclination of incisors during orthodontic treatments may influence these anatomical relationships. Our study aimed to assess the spatial relationship between maxillary central incisors and the surrounding alveolar bone and nasopalatine canal.

Interplay Of Periodontal Bacterial Metabolites In The Progression Of Coronary Artery Disease: A System Biological Approach, Janakiraman V

Annual Research Symposium

Purpose:

The purpose of this study is to investigate the intricate relationship between periodontal disease (PD) and coronary artery disease (CAD), as evidenced by epidemiological associations. Metalloproteinase inhibitor (TIMP1) plays a pivotal role in cellular signaling, differentiation, cell death, and migration by binding to target metalloproteinases, forming complexes with other molecules (collagenases) to inactivate them. However, the expression of TIMP1 is reduced in both PD and CAD, leading to an upregulation of other metalloproteinases. This research explores the hypothesis that metabolites released from (Porphyromonas gingivalis), a prevalent bacterium in atherosclerotic patients, may inhibit TIMP1, thereby influencing CAD progression. …

Implementation Of Best Practice When Collecting Blood Cultures In The Emergency Department (Ed), Parker Grossman

Annual Research Symposium

The purpose of this study is to compare blood culture contamination rates in the ED before and after educational in-services on best practice.

Overlooked Dental Disease In Cbct Imaging And The Impact Of Oral Radiologist Interpretation, Jared Fausnaught

Annual Research Symposium

This study aims to underscore the necessity for a comprehensive interpretation of Cone Beam Computed Tomography (CBCT) volume images obtained by dentists. The research demonstrates and quantifies potentially overlooked dental pathology, categorizing incidental findings into three groups: 1) requiring some form of treatment or follow-up, 2) necessitating follow-up (monitoring) only, and 3) demanding no further treatment or follow-up.

Photodynamic Therapy Effects In The Treatment Of Residual Periodontal Pockets, Kade Janes

Annual Research Symposium

This systematic review examined the adjunctive effect of photodynamic therapy to treat residual pockets.

Sulforaphane Pre-Treatment Improves Cytoprotection Against Opportunistic Pathogens, Robert Darby, Nathan Clark

Annual Research Symposium

Alcohol is associated with increased mortality and morbidity globally. Pulmonary infections with opportunistic pathogens can occur in healthy humans; however, binge alcohol intoxication (≥ 0.08% BAC) is a major risk factor. We have previously shown that a single dose of alcohol comparable to binge alcohol intoxication increases infection by reducing alveolar macrophage function in vivo. The aim of this study was to 1) test the therapeutic potential of the phytonutrient sulforaphane (SFN) given as a pre-treatment, and 2) test the alcohol-induced effects on phagocytic function in murine and human macrophages in vitro.

Unveiling The Dynamics: Comparing Drug Release And Cell Viability Of Advanced-Plate Rich Fibrin(A-Prf) And Titanium Prepared Platelet Rich Fibrin(T-Prf) Both Loaded With Simvastatin - An In-Vitro Study, Uma S

Annual Research Symposium

Autologous Platelet rich fibrin (PRF) has gained clinical significance in recent years for regeneration procedures. Advanced approaches, including the combination of PRF with drugs (simvastatin) that up regulate intrinsic bone growth factors that improve periodontal regeneration are of great interest. The aim of the study was to compare the drug release kinetics & cell viability analysis of simvastatin loaded A-PRF versus T-PRF and which one can be used as a potential carrier for simvastatin in terms of sustained release.

Meet An Ipe/Cp Student Champion From Thomas Jefferson University, Joria Le, Rn, Bsn

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

My first involvement with JCIPE programs was with the Interprofessional Palliative Care (IPC) program. Here, I was able to meet diverse students across Jefferson from Couple and Family Therapy, Medicine, Nursing, Physical Therapy, and more. Together, we addressed case studies with our various backgrounds and learned how to build upon each other’s strengths as a precursor to our future in the field. Especially coming from a Nursing background and now shifting towards medicine, it was a great experience to apply my knowledge and intertwine it with other fields.

Since then, I have immersed myself with research relating to the Health …

Meet An Ipe/Cp Staff Champion From Thomas Jefferson University, Mollie Cherson, Mphil, Lcsw

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In June 2021, the Integrated Behavioral Health (IBH) team was invited by JCIPE to pilot a new series of interprofessional sessions for primary care teams utilizing the ECHO (Extension for Community Healthcare Outcomes). This model has been utilized and researched worldwide to help with disseminating information across various subject matters within healthcare, with the goal of decreasing health disparities. Through use of subject matter experts, brief didactic education, and case consultations, communities of learners come together to enhance patient care and health outcomes.

The IBH team, which consists of clinicians from behavioral health, primary care, nutrition, occupational therapy, psychiatry, pharmacy, …

Translation Of Collaborative Skills From Undergraduate Interprofessional Education Curriculum To The Workplace: Results Of A Pilot Program, Erin Choice, Phd, Cscs, Shelene Thomas, Pt, Dpt, Edd, Gcs, Fnap

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Background

Interprofessional education (IPE) has become an increasingly necessary component of healthcare and health science curricula (Institute of Medicine, 2015; World Health Organization, 2010). However, the longitudinal impact of IPE and students’ ability to transfer knowledge and skills from the classroom to the workplace remains unknown (Breitbach et al., 2020). Training future healthcare providers (i.e., physical therapists, occupational therapists, exercise scientists) to work in interprofessional (IP) teams should arguably begin at the undergraduate (UG) level, rather than graduate level, in order to improve effective translation of skills to the workplace (Breitbach et al., 2020; Cooper et al., 2001; Murdoch et …

Team Care Planning: Black Maternal Health Case, Kenna Hersey, Ba

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

In support of Thomas Jefferson University’s effort to be on the cutting edge of care, JCIPE (Jefferson Center for Interprofessional Practice & Education) supports educational programs that focus on understanding and addressing health disparities. Team Care Planning (TCP) is an educational simulation experience where teams of students from different professions collaborate with each other, and interact with standardized patients, to create a care plan. The initial case developed for TCP involves an interprofessional student team developing a discharge plan for an older adult who was hospitalized after a stroke. The interprofessional student team meets with the patient and her adult …

Spotlight On An Interprofessional Clinical Team, Andrew Chapman, Md, Emily Hajjar, Pharmd, Ms, Bcps, Bcacp, Bcgp, Lora Rhodes, Msw, Lsw, Melissa Denton, Rdn, Cso, Ldn, Lauren Hersh, Md

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

Take a closer look at a clinical team at Thomas Jefferson University Hospital and how they practice interprofessionally every day!

The Senior Adult Oncology (SAO) Center at Jefferson Health focuses on cancer care for adults over the age of sixty-five, taking a whole-person approach in creating a personalized treatment plan.

JCIPE interviewed an SAO team about their roles, their interprofessional dynamic, and what they have learned from each other. The team then reviewed the case of C.S.

Who Are We Inviting To The Ipe Table?, Daniel S. Ferguson, Ms

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

“Of all the forms of inequality, injustice in health care is the most shocking and inhumane.” – Martin Luther King

Health outcomes and life expectancy in the United States of America differ substantially based on race. For example, people of color are more likely to die of cardiovascular disease or stroke; more likely to have diabetes; and have higher infant and maternal mortality rates as compared to their white counterparts (Frieden, 2013). Achieving health equity is a key focus of Healthy People 2030 (HHS, 2013), which prioritizes addressing social determinants of health, including access to timely, high-quality healthcare and effective …

Impact Of Non-Surgical Periodontal Treatment On Salivary Hif-1Α In Gingivitis & Periodontitis Patients, Srijanani S

Annual Research Symposium

To estimate and compare the level of salivary HIF-1α in periodontally & systemically healthy volunteers, generalized chronic gingivitis & periodontitis patients before and after non-surgical periodontal treatment.

Exploring The Resilience Of Two Commercial Suturing Materials Subjected To Thermocycling And Chlorhexidine Immersion: An In Vitro Study, Devadharshini Chandrasekar

Annual Research Symposium

To evaluate the durability of two commercially available suture materials (non absorbable Black Braided Silk and absorbable polyglactin 910) subjected to thermocycling after immersing in Chlorhexidine mouthwash.

Euglycemic Diabetic Ketoacidosis Secondary To Sodium Glucose 2 Transport Inhibitor: A Case Report, Alexis Duevel, Edward Ramirez

Annual Research Symposium

The purpose of this case report is to highlight the emergence of a rare adverse drug reaction (ADR), euglycemic diabetic ketoacidosis (EDKA), associated with the use of sodium glucose transport 2 (SGLT2) inhibitors.EDKA is a rare and often misdiagnosed condition, due to the absence of hyperglycemia, but represents a life-threatening emergency. We present a unique case of a 35-year-old female patient with a past medical history of diabetes and recent diagnosis of Hashimoto’s thyroiditis. The primary objective is to provide valuable insights and education to the medical community regarding this infrequent yet significant complication. Ultimately, the goal is to enhance …

Jcipe Updates

Collaborative Healthcare: Interprofessional Practice, Education and Evaluation (JCIPE)

JCIPE Updates