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2012

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Articles 1 - 30 of 10594

Full-Text Articles in Medicine and Health Sciences

Results Of The National Council Of State Boards Of Nursing National Simulation Survey: Part Ii, Suzan Kardong-Edgren, Janet Willhaus, Deborah Bennett, Jennifer Hayden Aug 2013

Results Of The National Council Of State Boards Of Nursing National Simulation Survey: Part Ii, Suzan Kardong-Edgren, Janet Willhaus, Deborah Bennett, Jennifer Hayden

Janet Willhaus

Background: The purpose of this article is to report additional data gathered during the National Council of State Boards of Nursing 2010 nationwide simulation survey of 1,729 nursing programs in the United States. It serves as a companion article to the initial survey data reported by Hayden in 2010.

Method: All prelicensure nursing programs in the United States were mailed the survey; 62% of programs (N ¼ 1,060) receiving the survey responded. This article presents respondents’ answers to an additional eight questions about a program’s use of simulation and thoughts on various aspects of simulation, not reported ...


The Influence Of Local Food Environments On Adolescents’ Food Purchasing Behaviors, Meizi He, Patricia Tucker, Jason Gilliland, Jennifer Irwin, Kristian Larsen, Paul Hess May 2013

The Influence Of Local Food Environments On Adolescents’ Food Purchasing Behaviors, Meizi He, Patricia Tucker, Jason Gilliland, Jennifer Irwin, Kristian Larsen, Paul Hess

Trish Tucker

This study examined the relationship between the neighborhood food environment and the food purchasing behaviors among adolescents. Grade 7 and 8 students (n = 810) at 21 elementary schools in London, Ontario, Canada completed a questionnaire assessing their food purchasing behaviors. Parents of participants also completed a brief questionnaire providing residential address and demographic information. A Geographic Information System (GIS) was used to assess students’ home and school neighborhood food environment and land use characteristics. Logistic regression analysis was conducted to assess the influence of the home neighborhood food environment on students’ food purchasing behaviors, while two-level Hierarchical Non-Linear Regression Models ...


The Change Program: Comparing An Interactive Versus Standardized Obesity Intervention On Students' Self-Esteem, Functional Health Status And Self-Efficacy For Performing Physical Activity And Nutrition Behaviours, Erin Pearson, Jennifer Irwin, Don Morrow Jan 2013

The Change Program: Comparing An Interactive Versus Standardized Obesity Intervention On Students' Self-Esteem, Functional Health Status And Self-Efficacy For Performing Physical Activity And Nutrition Behaviours, Erin Pearson, Jennifer Irwin, Don Morrow

Donald Morrow

No abstract provided.


Health Care Practitioners’ Perceptions Of Motivational Interviewing Training For Facilitating Behavior Change Among Patients, Erin Wiley, Jennifer Irwin, Don Morrow Jan 2013

Health Care Practitioners’ Perceptions Of Motivational Interviewing Training For Facilitating Behavior Change Among Patients, Erin Wiley, Jennifer Irwin, Don Morrow

Donald Morrow

No abstract provided.


The Level Of Cultural Responsiveness And Its Preparation Among Grand Valley State University’S Occupational Therapy Graduates, Kathleen Kovach, Rebecca Palmitier, Robyn Ward Dec 2012

The Level Of Cultural Responsiveness And Its Preparation Among Grand Valley State University’S Occupational Therapy Graduates, Kathleen Kovach, Rebecca Palmitier, Robyn Ward

Education

Background: In a field that aims to be holistic and client-centered, occupational therapists need to consider their client's culture. Culture is comprised of values, beliefs, and lifestyles and will affect the therapy process (Cheung, Shah, & Muncer, 2002; Cole, Stevenson, & Rogers, 2009). To truly treat clients holistically, therapists need to be culturally responsive in their practice, considering factors which influence therapy and its outcomes. Occupational therapy education programs, therefore, need to prepare its students to be culturally responsive practitioners. This research examined whether Grand Valley State University (GVSU) Occupational Therapy (OT) graduates are culturally responsive and how the program is preparing them in this area

Method: A mixed-methods study that utilized a concurrent triangulation strategy was used. A questionnaire with close-ended, Likert-type scale questions and an open-ended question was used to gather data. The questionnaire consisted of the Cultural Awareness and Sensitivity Questionnaire (Cheung et al., 2002) and researcher developed questions that were specific to GVSU's OT program. The questionnaire was sent to 148 GVSU OT graduates through an online survey tool (SurveyGizmo); 45 participants responded.

Results: Results showed that only 17.1% of graduates were fully culturally responsive; yet the majority had higher levels of cultural responsiveness. Graduates reported that both classroom experiences and fieldwork increased their cultural responsiveness, and more believed that fieldwork had an impact on their cultural responsiveness than classroom experiences. The qualitative results support this as well. Some graduates reported ...


Formative Development Of A Culturally Appropriate Mammography Screening Campaign For Low-Income African-American Women., Kimberly D. Leeks, Ingrid J. Hall, C. Ashani Johnson-Turbes, Ngozi Kamalu, Yasmine Zavahir Dec 2012

Formative Development Of A Culturally Appropriate Mammography Screening Campaign For Low-Income African-American Women., Kimberly D. Leeks, Ingrid J. Hall, C. Ashani Johnson-Turbes, Ngozi Kamalu, Yasmine Zavahir

Journal of Health Disparities Research and Practice

The purpose of this qualitative study was to conduct a formative evaluation of messages and materials to inform the development of a promotional, health campaign designed to increase breast cancer screening awareness and utilization among low-income, uninsured African American women through the National Breast and Cervical Cancer Early Detection Program (NBCCEDP) in Savannah and Macon, Georgia (GA). A priority of CDC is to understand why women eligible for screening through the NBCCEDP do not participate in NBCCEDP screening services as well as to identify effective strategies for increasing enrollment among NBCCEDP-eligible women who have never received breast cancer screening. As ...


Ethnic And Gender Differences In Psychosocial Factors In Native Hawaiian, Other Pacific Islanders, And Asian American Adults With Type 2 Diabetes, Jillian Inouye, Dongmei Li, James Davis, Richard Arakaki Dec 2012

Ethnic And Gender Differences In Psychosocial Factors In Native Hawaiian, Other Pacific Islanders, And Asian American Adults With Type 2 Diabetes, Jillian Inouye, Dongmei Li, James Davis, Richard Arakaki

Journal of Health Disparities Research and Practice

This study examined the differences between 207 Asians and Native Hawaiian, other Pacific Islanders (NHOPI) with type 2 diabetes among various psychosocial measures. Responses to five multivariable regression models including the Diabetes Quality of Life Questionnaire (DQOL) and Short Form -36® Health Survey (SF-36) were analyzed. Differences were determined by linear contrasts in the multivariate linear regression models after adjusted for multiple demographic and socioeconomic variables. Compared to Asians, NHOPIs perceived a lower impact of diabetes on their quality of life; highlighting differences in perceptions of self-efficacy and self-care activities. Females did better on their diet while males perceived better ...


Housing, The Neighborhood Environment, And Physical Activity Among Older African Americans, Lonnie Hannon Iii, Patricia Sawyer, Richard M. Allman Dec 2012

Housing, The Neighborhood Environment, And Physical Activity Among Older African Americans, Lonnie Hannon Iii, Patricia Sawyer, Richard M. Allman

Journal of Health Disparities Research and Practice

Abstract

This study examines the association of neighborhood environment, as measured by housing factors, with physical activity among older African Americans. Context is provided on the effects of structural inequality as an inhibitor of health enhancing neighborhood environments. The study population included African Americans participating in the UAB Study of Aging (n=433). Participants demonstrated the ability to walk during a baseline in-home assessment. The strength and independence of housing factors were assessed using neighborhood walking for exercise as the outcome variable. Sociodemographic data, co-morbid medical conditions, and rural/urban residence were included as independent control factors. Homeownership, occupancy, and ...


Racial Disparities In Pain Management In Primary Care, Miriam Ezenwa Dec 2012

Racial Disparities In Pain Management In Primary Care, Miriam Ezenwa

Journal of Health Disparities Research and Practice

This descriptive, cross-sectional, secondary data analysis was conducted to examine racial disparities in pain management of primary care patients with chronic nonmalignant pain using chronic opioid therapy. Data from 891 patients, including 201 African Americans and 691 Caucasians were used to test an explanatory model for these disparities. We predicted that: (1) African American patients would report worse pain management and poor quality of life (QOL) than Caucasians; (2) the association between race and pain management would be mediated by perceived discrimination relating to hopelessness; and (3) poor pain management would negatively affect QOL. Results revealed significant differences between African ...


Research News: 2012, No. 2, University Of Mississippi. School Of Pharmacy Dec 2012

Research News: 2012, No. 2, University Of Mississippi. School Of Pharmacy

Research News: Grants and Publications (2000-2014)

Grants and contracts recently awarded


Earth Is (Mostly) Flat: Apportionment Of The Flux Of Continental Sediment Over Millennial Time Scales, Jane K. Willenbring, Alexandru T. Codilean, Brandon Mcelroy Dec 2012

Earth Is (Mostly) Flat: Apportionment Of The Flux Of Continental Sediment Over Millennial Time Scales, Jane K. Willenbring, Alexandru T. Codilean, Brandon Mcelroy

Faculty of Science, Medicine and Health - Papers: part A

We use a new compilation of global denudation estimates from cosmogenic nuclides to calculate the apportionment and the sum of all sediment produced on Earth by extrapolation of a statistically significant correlation between denudation rates and basin slopes to watersheds without denudation rate data. This robust relationship can explain approximately half of the variance in denudation from quartz-bearing topography drained by rivers using only mean slopes as the predictive tool and matches a similar fit for large river basins. At slopes >200 m/km, topography controls denudation rates. Controls on denudation in landscapes where average slopes are 10 mm/k ...


Potentials And Limitations Of Real-Time Elastography For Prostate Cancer Detection: A Whole-Mount Step Section Analysis., Daniel Junker, Georg Schäfer, Friedrich Aigner, Peter Schullian, Leo Pallwein-Prettner, Jasmin Bektic, Wolfgang Horninger, Ethan J Halpern, Ferdinand Frauscher Dec 2012

Potentials And Limitations Of Real-Time Elastography For Prostate Cancer Detection: A Whole-Mount Step Section Analysis., Daniel Junker, Georg Schäfer, Friedrich Aigner, Peter Schullian, Leo Pallwein-Prettner, Jasmin Bektic, Wolfgang Horninger, Ethan J Halpern, Ferdinand Frauscher

Department of Radiology Faculty Papers

OBJECTIVES: To evaluate prostate cancer (PCa) detection rates of real-time elastography (RTE) in dependence of tumor size, tumor volume, localization and histological type.

MATERIALS AND METHODS: Thirdy-nine patients with biopsy proven PCa underwent RTE before radical prostatectomy (RPE) to assess prostate tissue elasticity, and hard lesions were considered suspicious for PCa. After RPE, the prostates were prepared as whole-mount step sections and were compared with imaging findings for analyzing PCa detection rates.

RESULTS: RTE detected 6/62 cancer lesions with a maximum diameter of 0-5 mm (9.7%), 10/37 with a maximum diameter of 6-10 mm (27%), 24/34 ...


(R)-Β-Lysine Modified Elongation Factor P Functions In Translation Elongation, Tammy J. Bullwinkle, S. Betty Zou, Andrei Rajkovic, Steven J. Hersch, Sara Elgamal, Nathaniel Robinson, David Smil, Yuri Bolshan, William Wiley Navarre, Michael Ibba Dec 2012

(R)-Β-Lysine Modified Elongation Factor P Functions In Translation Elongation, Tammy J. Bullwinkle, S. Betty Zou, Andrei Rajkovic, Steven J. Hersch, Sara Elgamal, Nathaniel Robinson, David Smil, Yuri Bolshan, William Wiley Navarre, Michael Ibba

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

Post-translational modification of bacterial elongation factor P (EF-P) with (R)-β-lysine at a conserved lysine residue activates the protein in vivo and increases puromycin reactivity of the ribosome in vitro. The additional hydroxylation of EF-P at the same lysine residue by the YfcM protein has also recently been described. The roles of modified and unmodified EF-P during different steps in translation, and how this correlates to its physiological role in the cell, have recently been linked to the synthesis of polyproline stretches in proteins. Polysome analysis indicated that EF-P functions in translation elongation, rather than initiation as proposed previously. This ...


Preparasi, Karakterisasi Dan Evaluasi Pelepasan Obat Dari Beads Kalsium Alginat Deksametason Dengan Metode Gelasi Ionik, Christye Aulia, Joshita Djajadisastra Dec 2012

Preparasi, Karakterisasi Dan Evaluasi Pelepasan Obat Dari Beads Kalsium Alginat Deksametason Dengan Metode Gelasi Ionik, Christye Aulia, Joshita Djajadisastra

Majalah Ilmu Kefarmasian

Inflammatory Bowel Disease (IBD) is a disease of inflammation in the colon. Targeted delivery systems for the treatment of IBD is designed to increase the drug concentration in the local tissue. Dexamethasone is a drug having anti-inflammatory and antifibrosis effects which is used to repair scar tissue arising from postoperative IBD. This research purpose to create calciumalginate beads dexamethasone to be released only in the colon. Beads were made by using sodium-alginate and Ca2+ as crosslinker by ionic gelation method, with ratio between sodium alginate-dexamethasone (3:1). A concentration of solution sodium alginate 3 % b/v with variation concentration of ...


Successfully Climbing The "Stairs": Surmounting Failed Translation Of Experimental Ischemic Stroke Treatments, Michael Kahle, Gregory J. Bix Dec 2012

Successfully Climbing The "Stairs": Surmounting Failed Translation Of Experimental Ischemic Stroke Treatments, Michael Kahle, Gregory J. Bix

Sanders-Brown Center on Aging Faculty Publications

The Stroke Therapy Academic Industry Roundtable (STAIR) provided initial (in 1999) and updated (in 2009) recommendations with the goal of improving preclinical stroke therapy assessment and to increase the translational potential of experimental stroke treatments. It is important for preclinical stroke researchers to frequently consider and revisit these concepts, especially since promising experimental stroke treatments continue to fail in human clinical trials. Therefore, this paper will focus on considerations for several key aspects of preclinical stroke studies including the selection and execution of the animal stroke model, drug/experimental treatment administration, and outcome measures to improve experimental validity and translation ...


Regulation Of The Mouse And Human Β-Globin Genes By Krüppel Like Transcription Factors Klf1 And Klf2, Yousef N. Alhashem Dec 2012

Regulation Of The Mouse And Human Β-Globin Genes By Krüppel Like Transcription Factors Klf1 And Klf2, Yousef N. Alhashem

Theses and Dissertations

Krüppel-like factors KLF1 and KLF2 are closely related transcription factors with three zinc finger domains in their carboxy-termini. KLF1 (erythroid Krüppel-like factor, or EKLF) plays essential roles in embryonic and adult erythropoiesis. KLF2 is a positive regulator of the mouse and human embryonic β- globin genes. KLF1 and KLF2 have overlapping roles in embryonic erythropoiesis, as demonstrated using single and double knockout (KO) mouse models. Ablation of the KLF1 or KLF2 gene causes embryonic lethality, and double KO embryos are more anemic and die sooner than either single KO. We have shown that KLF1 and KLF2 positively regulate the human ...


Commentary By Williams, Kristine Williams Dec 2012

Commentary By Williams, Kristine Williams

Kristine N. Williams

No abstract provided.


Enhancing Communication With Older Adults: Overcoming Elderspeak, Kristine Williams, S Kemper, M Hummert Dec 2012

Enhancing Communication With Older Adults: Overcoming Elderspeak, Kristine Williams, S Kemper, M Hummert

Kristine N. Williams

No abstract provided.


Elderspeak: Impact On Geriatric Care, Kristine Williams Dec 2012

Elderspeak: Impact On Geriatric Care, Kristine Williams

Kristine N. Williams

No abstract provided.


A Book Review Of De Bot And Makoni, Language And Aging In Multilingual Contexts, Kristine Williams Dec 2012

A Book Review Of De Bot And Makoni, Language And Aging In Multilingual Contexts, Kristine Williams

Kristine N. Williams

No abstract provided.


Gerontological Nursing, Kristine Williams Dec 2012

Gerontological Nursing, Kristine Williams

Kristine N. Williams

No abstract provided.


Reasoning Exercises In Assisted Living (Real) Pilot Study, Kristine Williams Dec 2012

Reasoning Exercises In Assisted Living (Real) Pilot Study, Kristine Williams

Kristine N. Williams

No abstract provided.


A Case Study Of Resistiveness To Care And Elderspeak, Jacqueline Cunningham, Kristine Williams Dec 2012

A Case Study Of Resistiveness To Care And Elderspeak, Jacqueline Cunningham, Kristine Williams

Kristine N. Williams

Resistiveness to care (RTC) by persons with dementia significantly adds to subjective and objective burden for caregivers and may be triggered by environmental factors, including communication. This case study evaluated behavioral responses of a nursing home resident with dementia to nursing staff use of elderspeak communication (infantilizing speech). Four videotaped staff-resident interactions that were previously recorded were coded for staff elderspeak communication and resident RTC. Total elderspeak scores (M = 29.5, SD = 25.74) and RTC scores (M = 8.75, SD = 13.79) were correlated r = 0.93, p = .03. This preliminary single-subject observational study suggests a relationship between staff ...


Exploring Interventions To Reduce Cognitive Decline In Aging, Kristine Williams Dec 2012

Exploring Interventions To Reduce Cognitive Decline In Aging, Kristine Williams

Kristine N. Williams

No abstract provided.


Elderspeak In Institutional Care Of Older Adults, Kristine Williams Dec 2012

Elderspeak In Institutional Care Of Older Adults, Kristine Williams

Kristine N. Williams

No abstract provided.


Measuring The Person-Centeredness Of Caregivers Working With Nursing Home Residents With Dementia, Kristine Williams Dec 2012

Measuring The Person-Centeredness Of Caregivers Working With Nursing Home Residents With Dementia, Kristine Williams

Kristine N. Williams

No abstract provided.


Medicine In The Americas, Kristine A. Petre Mls, Cm, Ahip Dec 2012

Medicine In The Americas, Kristine A. Petre Mls, Cm, Ahip

Kristine A Petre, MLS, CM, AHIP

Medicine in the Americas is a freely available, searchable collection of historical medical Americana. The collection is part of the Digital Collections repository at the National Library of Medicine’s online digital archives. This review discusses the contents, searching functions, and additional features available in the collection.


National Longitudinal Survey Of Public Health Systems: Comparative Report Of 2012 Results, Glen Mays Dec 2012

National Longitudinal Survey Of Public Health Systems: Comparative Report Of 2012 Results, Glen Mays

Glen Mays

The third wave of the National Longitudinal Survey of Public Health Systems was fielded in 2012 in a nationally-representative cohort of local communities. The survey measures the availability of 20 recommended public health activities in the community, the range of organizations that participate in performing each activity, and the perceived effectiveness of each activity. Prior waves of the survey were fielded in 1998 and 2006. Local health officials report data for this survey and receive a customized report of results that compare data for their community with national norms and with "peer groups" of similar communities. This document provides an ...


Circularized Synthetic Oligodeoxynucleotides Serve As Promoterless Rna Polymerase Iii Templates For Small Rna Generation In Human Cells, Christine I. Seidl, Lodoe Lama, Kevin Ryan Dec 2012

Circularized Synthetic Oligodeoxynucleotides Serve As Promoterless Rna Polymerase Iii Templates For Small Rna Generation In Human Cells, Christine I. Seidl, Lodoe Lama, Kevin Ryan

Publications and Research

Synthetic RNA formulations and viral vectors are the two main approaches for delivering small therapeutic RNA to human cells. Here we report findings supporting an alternative strategy in which an endogenous human RNA polymerase (RNAP) is harnessed to make RNA hairpin-containing small RNA from synthetic single-stranded DNA oligonucleotides. We report that circularizing a DNA template strand encoding a pre-microRNA hairpin mimic can trigger its circumtranscription by human RNAP III in vitro and in human cells. Sequence and secondary structure preferences that appear to promote productive transcription are described. The circular topology of the template is required for productive transcription, at ...


Piscine Myocarditis Virus (Pmcv) In Wild Atlantic Salmon Salmo Salar, Torstein Tengs Dr. Dec 2012

Piscine Myocarditis Virus (Pmcv) In Wild Atlantic Salmon Salmo Salar, Torstein Tengs Dr.

Dr. Torstein Tengs

Cardiomyopathy syndrome (CMS) is a severe cardiac disease of sea-farmed Atlantic salmon Salmo salar L., but CMS-like lesions have also been found in wild Atlantic salmon. In 2010 a double-stranded RNA virus of the Totiviridae family, provisionally named piscine myocarditis virus (PMCV), was described as the causative agent of CMS. In the present paper we report the first detection of PMCV in wild Atlantic salmon. The study is based on screening of 797 wild Atlantic salmon by real-time RT-PCR. The samples were collected from 35 different rivers along the coast of Norway, and all individuals included in the study were ...