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Full-Text Articles in Medicine and Health Sciences

A Case Analysis Of Partnered Research On Palliative Care For Refugees In Jordan And Rwanda, Sonya De Laat, Olive Wahoush, Rania Jaber, Wejdan Khater, Emmanuel Musoni, Ibraheem Abu Siam, Lisa Schwartz, Matthew Hunt, Lynda Redwood-Campbell, Laurie Elit, Elysée Nouvet, Rachel Yantzi, Kevin Bezanson, Carrie Bernard, Takhliq Amir, Ani Chénier, Gautham Krishnaraj, Corinne Schusterwallace Dec 2021

A Case Analysis Of Partnered Research On Palliative Care For Refugees In Jordan And Rwanda, Sonya De Laat, Olive Wahoush, Rania Jaber, Wejdan Khater, Emmanuel Musoni, Ibraheem Abu Siam, Lisa Schwartz, Matthew Hunt, Lynda Redwood-Campbell, Laurie Elit, Elysée Nouvet, Rachel Yantzi, Kevin Bezanson, Carrie Bernard, Takhliq Amir, Ani Chénier, Gautham Krishnaraj, Corinne Schusterwallace

Health Studies Publications

© 2021, The Author(s). Background: This case analysis describes dilemmas and challenges of ethical partnering encountered in the process of conducting a research study that explored moral and practical dimensions of palliative care in humanitarian crisis settings. Two contexts are the focus of this case analysis: Jordan, an acute conflict-induced refugee situation, and Rwanda, a protracted conflict-induced refugee setting. The study’s main goal was to better understand ways humanitarian organizations and health care providers might best support ethically and contextually appropriate palliative care in humanitarian contexts. An unintended outcome of the research was learning lessons about ethical dimensions of ...


Early Protein Intake Predicts Functional Connectivity And Neurocognition In Preterm Born Children, Emma G. Duerden, Benjamin Thompson, Tanya Poppe, Jane Alsweiler, Greg Gamble, Yannan Jiang, Myra Leung, Anna C. Tottman, Trecia Wouldes, Steven P. Miller, Jane E. Harding, Jane M. Alsweiler, Janene B. Biggs, Coila Bevan, Joanna M. Black, Frank H. Bloomfield, Kelly Fredell, Greg D. Gamble, Jane E. Harding, Sabine Huth, Yannan Jiang, Christine Kevan, Myra Leung, Geraint Phillips, Tanya Poppe, Jennifer A. Rogers, Heather Stewart, Benjamin S. Thompson Dec 2021

Early Protein Intake Predicts Functional Connectivity And Neurocognition In Preterm Born Children, Emma G. Duerden, Benjamin Thompson, Tanya Poppe, Jane Alsweiler, Greg Gamble, Yannan Jiang, Myra Leung, Anna C. Tottman, Trecia Wouldes, Steven P. Miller, Jane E. Harding, Jane M. Alsweiler, Janene B. Biggs, Coila Bevan, Joanna M. Black, Frank H. Bloomfield, Kelly Fredell, Greg D. Gamble, Jane E. Harding, Sabine Huth, Yannan Jiang, Christine Kevan, Myra Leung, Geraint Phillips, Tanya Poppe, Jennifer A. Rogers, Heather Stewart, Benjamin S. Thompson

Brain and Mind Institute Researchers' Publications

© 2021, The Author(s). Nutritional intake can promote early neonatal brain development in very preterm born neonates (< 32 weeks’ gestation). In a group of 7-year-old very preterm born children followed since birth, we examined whether early nutrient intake in the first weeks of life would be associated with long-term brain function and neurocognitive skills at school age. Children underwent resting-state functional MRI (fMRI), intelligence testing (Wechsler Intelligence Scale for Children, 5th Ed) and visual-motor processing (Beery-Buktenica, 5th Ed) at 7 years. Relationships were assessed between neonatal macronutrient intakes, functional connectivity strength between thalamic and default mode networks (DMN), and neuro-cognitive function using multivariable regression. Greater functional connectivity strength between thalamic networks and DMN was associated with greater intake of protein in the first week (β = 0.17; 95% CI 0.11, 0.23, p < 0.001) but lower intakes of fat (β = − 0.06; 95% CI − 0.09, − 0.02, p = 0.001) and carbohydrates (β = − 0.03; 95% CI − 0.04, − 0.01, p = 0.003). Connectivity strength was also associated with protein intake during the first month (β = 0.22; 95% CI 0.06, 0.37, p = 0.006). Importantly, greater thalamic-DMN connectivity strength was associated with higher processing speed indices (β = 26.9; 95% CI 4.21, 49.49, p = 0.02) and visual processing scores (β = 9.03; 95% CI 2.27, 15.79, p = 0.009). Optimizing early protein intake may contribute to promoting long-term brain health in preterm-born children.


A Critical Narrative Inquiry To Understand The Impacts Of An Overdose Prevention Site On The Lives Of Site Users, Abe Oudshoorn, Michelle Sangster Bouck, Melissa Mccann, Shamiram Zendo, Helene Berman, Jordan Banninga, Marlene J. Le Ber, Zayya Zendo Dec 2021

A Critical Narrative Inquiry To Understand The Impacts Of An Overdose Prevention Site On The Lives Of Site Users, Abe Oudshoorn, Michelle Sangster Bouck, Melissa Mccann, Shamiram Zendo, Helene Berman, Jordan Banninga, Marlene J. Le Ber, Zayya Zendo

Nursing Publications

© 2021, The Author(s). Background: Globally, communities are struggling to gain support for harm reduction strategies being implemented to address the impacts of substance use. A key part of this discussion is understanding and engaging with people who use drugs to help shape community harm reduction strategies. This study focused on how an overdose prevention site has influenced the lives of people who use drugs. Methods: A critical narrative method was utilized, centred on photo-narratives. Twenty-seven individuals accessing an overdose prevention site were recruited to participate in preliminary interviews. Sixteen participants subsequently took photographs to describe the impact of the ...


Structural Alterations In Cortical And Thalamocortical White Matter Tracts After Recovery From Prefrontal Cortex Lesions In Macaques, Ramina Adam, David J. Schaeffer, Kevin Johnston, Ravi S. Menon, Stefan Everling May 2021

Structural Alterations In Cortical And Thalamocortical White Matter Tracts After Recovery From Prefrontal Cortex Lesions In Macaques, Ramina Adam, David J. Schaeffer, Kevin Johnston, Ravi S. Menon, Stefan Everling

Brain and Mind Institute Researchers' Publications

Unilateral damage to the frontoparietal network typically impairs saccade target selection within the contralesional visual hemifield. Severity of deficits and the degree of recovery have been associated with widespread network dysfunction, yet it is not clear how these behavioural and functional brain changes relate with the underlying structural white matter tracts. Here, we investigated whether recovery after unilateral prefrontal cortex (PFC) lesions was associated with changes in white matter microstructure across large-scale frontoparietal cortical and thalamocortical networks. Diffusion-weighted imaging was acquired in four male rhesus macaques at pre-lesion, week 1, and week 8-16 post-lesion when target selection deficits largely recovered ...


Muting, Not Fragmentation, Of Functional Brain Networks Under General Anesthesia, Corson N. Areshenkoff, Joseph Y. Nashed, R. Matthew Hutchison, Melina Hutchison, Ron Levy, Douglas J. Cook, Ravi S. Menon, Stefan Everling, Jason P. Gallivan May 2021

Muting, Not Fragmentation, Of Functional Brain Networks Under General Anesthesia, Corson N. Areshenkoff, Joseph Y. Nashed, R. Matthew Hutchison, Melina Hutchison, Ron Levy, Douglas J. Cook, Ravi S. Menon, Stefan Everling, Jason P. Gallivan

Brain and Mind Institute Researchers' Publications

© 2021 Changes in resting-state functional connectivity (rs-FC) under general anesthesia have been widely studied with the goal of identifying neural signatures of consciousness. This work has commonly revealed an apparent fragmentation of whole-brain network structure during unconsciousness, which has been interpreted as reflecting a break-down in connectivity and a disruption of the brain's ability to integrate information. Here we show, by studying rs-FC under varying depths of isoflurane-induced anesthesia in nonhuman primates, that this apparent fragmentation, rather than reflecting an actual change in network structure, can be simply explained as the result of a global reduction in FC. Specifically ...


“I Am The Expert” : The Process Of Adolescent Transition In The Self-Management Of Hearing Healthcare. A Constructivist Grounded Theory Study, Christine N. Meston Apr 2021

“I Am The Expert” : The Process Of Adolescent Transition In The Self-Management Of Hearing Healthcare. A Constructivist Grounded Theory Study, Christine N. Meston

Electronic Thesis and Dissertation Repository

Adolescence is a time when adult behaviours become established and adolescents are more able to manage aspects of their healthcare. Research has examined adolescent transitions to self-manage their personal healthcare needs associated with chronic diseases. Providing children and adolescents with information about their health is an ongoing process and, as they mature, they should be allowed to take on more responsibility for their healthcare management. The purpose of this study was to explore the transition for adolescents who are deaf and hard of hearing toward the self-management of their hearing healthcare. A constructivist grounded theory approach was used to develop ...


Catechol-Containing Copolymers As An Active Ingredient For Denture Adhesives, Vincent Ying Wun Kong Apr 2021

Catechol-Containing Copolymers As An Active Ingredient For Denture Adhesives, Vincent Ying Wun Kong

Electronic Thesis and Dissertation Repository

Moisture inside the mouth adds challenge to making denture adhesives formulations. Some formulations have zinc to enhance adhesion on wet skin despite knowing the health hazards. Inspired by mussel foot proteins’ catechol unit’s strong underwater adhesion, nine catechol-containing copolymers (P1A-P3C) were synthesized by free radical polymerization of 3,4-dimethoxystyrene (3,4- DMS) with different styrene derivatives followed by deprotection. P1A-P3C were used to make Fn(P)-C-PBS denture adhesive formulations which had suitable shear stresses around ≥ 5 kPa satisfying ISO 10873. In-situ NMR studies of free radical polymerization of 3,4 - DMS and styrene derivatives allowed computation of their ...


Hiv-1 Drug Resistance To Integrase Strand Transfer Inhibitors In Hiv-1 Non-B Subtypes, Emmanuel Ndashimye Apr 2021

Hiv-1 Drug Resistance To Integrase Strand Transfer Inhibitors In Hiv-1 Non-B Subtypes, Emmanuel Ndashimye

Electronic Thesis and Dissertation Repository

Human immunodeficiency syndrome (HIV-1) has infected over 75 million people and over 35 million have succumbed to virus related illnesses. Despite access to a variety of antiretroviral therapy (ART) options, ART programs have been disproportionally spread in the world with low-and middle-income countries (LMICs) facing challenges to access the most potent ART options. With less potent ART remaining in use in LMICs, HIV-1 drug resistance (HIVDR) presents a growing challenge in LMICs. Since approval of the first-generation integrase strand transfer inhibitor (INSTIs), Raltegravir (RAL) in 2007, INSTIs remain the best choice as a backbone of ART. Access to second generation ...


Barriers To Safety Planning And Best Practices For Supporting Survivors Of Domestic Violence In Rural, Remote, And Northern Regions, Sara Kohtala Apr 2021

Barriers To Safety Planning And Best Practices For Supporting Survivors Of Domestic Violence In Rural, Remote, And Northern Regions, Sara Kohtala

Electronic Thesis and Dissertation Repository

Domestic violence (DV) or intimate partner violence (IPV) is defined as physical, emotional, psychological, or sexual harm in an intimate relationship. In extreme cases, it may culminate in domestic homicide which is defined as the killing of an intimate partner, their children or their family members. Intimate partner violence and domestic homicide is prevalent worldwide. Over ninety-nine thousand reports of DV were made to police in Canada in 2018. According to the Canadian Domestic Homicide Prevention Initiative for Vulnerable Populations, some victims may face greater barriers in receiving assistance on a timely basis such as immigrants and refugees, Indigenous people ...


Therapist Perception Of The Clarity And Implementability Of Relevant Recommendations From American Academy Of Orthopedic Surgeon’S Distal Radius Fracture Clinical Practice Guidelines, Saravanan Esakki Apr 2021

Therapist Perception Of The Clarity And Implementability Of Relevant Recommendations From American Academy Of Orthopedic Surgeon’S Distal Radius Fracture Clinical Practice Guidelines, Saravanan Esakki

Electronic Thesis and Dissertation Repository

Fractures of the distal radius are common and can cause substantial either transient or permanent impairment and disability.

Clinical practice guidelines (CPGs) are systematically developed statements or recommendations based on the best available evidence and aimed at assisting health care practitioners in clinical decision-making. Many professional organizations have developed practice guidelines for common clinical conditions. The overall objective of this thesis is to evaluate the therapist's perception of the clarity and implementability of rehabilitation relevant recommendations from The American Academy of Orthopaedic Surgeons (AAOS) CPG for distal radius fractures (DRF) and to identify the quality of CPG related to ...


Novel Imaging Tools Reveal The Dynamics Of The Myocardial Growth Hormone Secretagogue Receptor In Heart Disease And Heart Failure, Rebecca Sullivan Apr 2021

Novel Imaging Tools Reveal The Dynamics Of The Myocardial Growth Hormone Secretagogue Receptor In Heart Disease And Heart Failure, Rebecca Sullivan

Electronic Thesis and Dissertation Repository

Heart disease (HD) is the leading cause of mortality worldwide. Currently, diagnosis is based on clinical features, imaging, and circulating cardiac biomarkers. Cardiac imaging technologies, such as echocardiography and cardiac magnetic resonance imaging (cMRI), enable the non-invasive detection of changes in heart function. Although these modalities can detect changes in structure and anatomy, it is usually at later stages, where prevention may not be possible. In conjunction with imaging, circulating biomarkers of heart failure (HF), notably B-type natriuretic peptide (BNP) and cardiac troponin I and T, can be detected with increased levels in the blood. These biomarkers are associated with ...


Skin And Muscle Receptors Shape Coordinated Fast Feedback Responses In The Upper Limb, Christopher J. Forgaard, Sasha Reschechtko, Paul L. Gribble, J. Andrew Pruszynski Apr 2021

Skin And Muscle Receptors Shape Coordinated Fast Feedback Responses In The Upper Limb, Christopher J. Forgaard, Sasha Reschechtko, Paul L. Gribble, J. Andrew Pruszynski

Brain and Mind Institute Researchers' Publications

© 2021 Elsevier Ltd Despite many real-world examples where skin and muscle receptors must function in concert to support movement control, responses based on these sensory modalities are usually separated from one another in laboratory studies. Proprioception is often considered the domain of muscle receptors, whereas the skin's function is often assumed to be discriminative touch. This distinction understates the extent to which sensory feedback from skin and muscle work together to shape successful movement control. Here we review the functional characteristics and similarities between fast feedback responses of the upper limb originating from muscle stretch and skin slip. We ...


Experimental, Theoretical, And Translational Studies Of Rbc Distribution In Capillary Networks, Asher Mendelson Mar 2021

Experimental, Theoretical, And Translational Studies Of Rbc Distribution In Capillary Networks, Asher Mendelson

Electronic Thesis and Dissertation Repository

The purpose of this thesis was to evaluate the physiology of red blood cell (RBC) distribution in skeletal muscle capillary networks. Because this is the terminal site of oxygen exchange in the microcirculation, characterization of this fundamental process informs an understanding of how microvascular blood flow regulation matches oxygen supply with local tissue demand. Prior studies in this field have focused on small groups of capillaries, and have not linked capillary network structure with functional measurements, nor evaluated the temporal complexity of RBC distribution over physiologically-relevant scales. It is also unclear how the functional units called capillary modules – comprised of ...


Long-Term Patterns Of Acute Mental Health Service Use After A First Episode Of Psychosis: Examining Ongoing Psychiatric Care Beyond The Critical Period, Eugene Law Mar 2021

Long-Term Patterns Of Acute Mental Health Service Use After A First Episode Of Psychosis: Examining Ongoing Psychiatric Care Beyond The Critical Period, Eugene Law

Electronic Thesis and Dissertation Repository

The long-term patterns of acute mental health service use after treatment in an early psychosis intervention (EPI) program are not well known. The objective of this thesis was to investigate the long-term patterns of acute mental health service use. We used health administrative data to examine the patterns and risk factors associated with acute mental health service use over the of 5- to 10-year period post-EPI admission. Between years 5 to 10 post-EPI admission, approximately one quarter of people contacted acute mental health services. Factors associated with acute mental health service use during this period included younger age at admission ...


Pleurodesis Using Hypertonic Glucose Administration To Treat Post-Operative Air Leaks Following Lung Resection Surgery (Plug): Phase I Trial, Mehdi Qiabi Mar 2021

Pleurodesis Using Hypertonic Glucose Administration To Treat Post-Operative Air Leaks Following Lung Resection Surgery (Plug): Phase I Trial, Mehdi Qiabi

Electronic Thesis and Dissertation Repository

Introduction: Pulmonary air leaks from unhealed lung tissue are one of the most common complications after lung surgery. This adverse event leads to a delay in chest tube removal, prolonged pain, increased infections, prolonged hospital stay, and increased costs to the health care system. Objective: To define the most appropriate safe dose of dextrose 50% (D50) to seal air leaks in patients that have undergone lung resection surgery. Primary outcome was the occurrence of any adverse event. Methods: Prospective, single-arm, single-center, rule-based escalation traditional 3+3 design phase I trial where patients with an active air leak on postoperative day ...


"It's Certainly Someone's Job": The Roles Of Health Care Providers In Homelessness Prevention, Kayla May Mar 2021

"It's Certainly Someone's Job": The Roles Of Health Care Providers In Homelessness Prevention, Kayla May

Electronic Thesis and Dissertation Repository

Comprehensive strategies to end all homelessness must include prevention-focused approaches in addition to the provision of emergency services and responsive housing programs. This qualitative descriptive study examines nurse practitioners’ and physicians’ perceptions of their roles in homelessness prevention and their current involvement in prevention-oriented activities. Data from interviews with health care providers was analyzed using a blended inductive and deductive approach, guided by a Framework for Homelessness Prevention and findings from a document analysis. The results highlighted health care providers’ conceptualizations of poverty, housing instability, and associated risk factors and found that providers consider information about patients’ social and economic ...


Effects Of Branched-Chain Amino Acid Supplementation On Exercise Induced Muscle Damage And Delayed Onset Of Muscle Soreness After A Bout Of Eccentric Exercise, Crystal Lee Mar 2021

Effects Of Branched-Chain Amino Acid Supplementation On Exercise Induced Muscle Damage And Delayed Onset Of Muscle Soreness After A Bout Of Eccentric Exercise, Crystal Lee

Electronic Thesis and Dissertation Repository

Branched-chain amino acids (BCAA) have the potential to reduce both exercise-induced muscle damage (EIMD) and delayed onset of muscle soreness (DOMS) after a bout of eccentric contractions (ECC). The purpose of this study was to determine the effects of BCAA supplementation for 12 days prior to and for an additional 7 days following a bout of ECC on EIMD and DOMS. Sixteen women with no prior experience with strength training were assigned randomly to a BCAA group or a placebo group. Only four participants completed the trial due to COVID-19 (another completed 72h of recovery and was included). Participants supplemented ...


Exploring The Mental Health Experiences Of African, Caribbean, And Black Youth In London, Ontario, Lily Yosieph Mar 2021

Exploring The Mental Health Experiences Of African, Caribbean, And Black Youth In London, Ontario, Lily Yosieph

Electronic Thesis and Dissertation Repository

This qualitative study explores the mental health experiences of African, Caribbean, and Black (ACB) youth in London, Ontario, investigating how the factors of race, gender, culture, and place have shaped their perceptions and experiences of mental health. The data collection and analysis were conducted using a phenomenological approach and a critical lens informed by feminist, intersectionality, and critical race theories. These data illuminate the ways in which these young people’s attitudes toward mental health and help-seeking strategies are impacted by broader social constructs and community expectations, which they navigate and often resist in their everyday lives. Their insights can ...


Association Between Air Pollution And Incidence Of Dementia: A Systematic Review And Meta-Analysis Of Cohort Studies, Ehsan Abolhasani Feb 2021

Association Between Air Pollution And Incidence Of Dementia: A Systematic Review And Meta-Analysis Of Cohort Studies, Ehsan Abolhasani

Electronic Thesis and Dissertation Repository

Objective. To estimate the risk of dementia in association with exposure to air pollutants.

Methods. Six databases were searched. Cohort studies that reported the hazard ratio (HR) of dementia in association with exposure to air pollutants in adults > 40y were included. For all meta-analyses, the random-effects model was used.

Results. A total of 16 and 13 studies were included in the systematic review and the meta-analysis, respectively. Risk of dementia increased by 4% per 1μg/m3 increase in fine particulate matter level (HR, 1.04; 95%CI, [1.02, 1.06]), which was statistically significant. The risk of dementia ...


The Relation Of Auditory Temporal Processing To Language Development And Other Cognitive Processes: Methodological And Conceptual Considerations, Rachael E. Smyth Feb 2021

The Relation Of Auditory Temporal Processing To Language Development And Other Cognitive Processes: Methodological And Conceptual Considerations, Rachael E. Smyth

Electronic Thesis and Dissertation Repository

Separate lines of research have demonstrated relations between auditory temporal processing and language ability and between information processing speed and intelligence. Because these processes have rarely been studied in the same sample, it is unclear how auditory temporal processing and information processing speed may operate together and how they may relate to cognitive functions including language. The overarching aim of this dissertation was to integrate these lines of research to better understand whether auditory temporal processing has a unique relation with language, or whether it relates more broadly to language and other cognitive functions as a part of global information ...


A Critical Review And Finite Element Study Of Structural Relaxation In Veneered 3y-Tzp Dental Structures, Prashant S. Shelar Feb 2021

A Critical Review And Finite Element Study Of Structural Relaxation In Veneered 3y-Tzp Dental Structures, Prashant S. Shelar

Electronic Thesis and Dissertation Repository

Yttria stabilized Tetragonal Zirconia Polycrystal (3Y-TZP) materials veneered with porcelain are preferred for clinical practice due to their bio-functionality, biocompatibility, and affordability. However, these materials are often subjected to premature clinical failures due to combination of subsurface flaws and tensile stresses within porcelains. This work focuses on performing a critical literature review and evaluating veneer characteristics, i.e. structural relaxation, to form a suitable explanation for the development of subsurface stresses. User material subroutines, UEXPAN and UTRS are developed, validated and integrated in ABAQUS finite element solver. With the use of validated models, it is shown that faster cooling rates ...


Evaluating Anesthetic Protocols For Non-Human Primate Functional Neuroimaging, Megha Verma Feb 2021

Evaluating Anesthetic Protocols For Non-Human Primate Functional Neuroimaging, Megha Verma

Electronic Thesis and Dissertation Repository

Functional magnetic resonance imaging (fMRI) is a non-invasive technique that can be used to measure a proxy of neural activity in vivo with high spatial specificity. One subject can be followed for a long period of time to assess changes in functional brain organization. However, fMRI is extremely sensitive to motion. The challenges of training non-human primates to reduce motion in an MRI scanner motivate the study of anesthesia which is commonly used to substitute for this training. In this thesis, I compare three different commonly used anesthetic protocols: isoflurane, propofol-fentanyl in combination, and fentanyl alone, to test which of ...


The Experiences Of Iraqi Refugees In Canada: A Life History Study Of War And Resilience In The Aftermath Of Migration, Nada Nessan Feb 2021

The Experiences Of Iraqi Refugees In Canada: A Life History Study Of War And Resilience In The Aftermath Of Migration, Nada Nessan

Electronic Thesis and Dissertation Repository

This thesis reports on a life history narrative on the experiences of Iraqi refugees who resettled in Canada after living through war. The aim of this study is to help change the narrow perspectives on the mental health of war affected populations to a broader perception shaped by cultural and social aspects and to inform the development of meaningful and cultural relevant programs and policies with a particular attention to the concept of resilience.

The first part of the study presents the chronological narratives, or profiles. of eight participants. The second part of the study is a thematic discussion of ...


Speech-Language Pathology Interventions And Ingredients That Support Social Communication And Language Of Preschoolers With Autism, Amanda Binns Feb 2021

Speech-Language Pathology Interventions And Ingredients That Support Social Communication And Language Of Preschoolers With Autism, Amanda Binns

Electronic Thesis and Dissertation Repository

One of the best predictors of long-term outcomes for autistic children is development of language and social communication skills. Therefore, it’s not surprising that speech and language therapy is one of the most frequently accessed interventions for children with suspected or diagnosed autism. From a public health and family well-being perspective, identifying effective social communication interventions and better understanding the specific components that contribute to their effectiveness is critical. However, there is a lack of clarity about the most effective interventions. This dissertation addressed this important topic through three studies.

Study 1 examined the literature on interventions provided by ...


Surgical Residency Workload, Perceptions And Educational Value: Implications For Competency- Based Medical Education, Eric Walser Feb 2021

Surgical Residency Workload, Perceptions And Educational Value: Implications For Competency- Based Medical Education, Eric Walser

Electronic Thesis and Dissertation Repository

Introduction: Surgical training has transitioned to competency-based medical education. There is incomplete understanding of current resident workload and how workload is perceived by trainees and faculty.

Methods: A prospective time-motion study was conducted in a Canadian general surgery training program. A web-based survey was used to compare observational data with faculty and learner perceptions of actual and ideal resident workloads and the educational value of workload components.

Results: 54 clinical periods were assessed (662.8 hours, 6375 individual events). 39.7% of time was spent on direct patient care, 33.2% on indirect patient care and 7.5% on education ...


Debt And Stress Amongst Orthodontic Residents, Timothy Renison Feb 2021

Debt And Stress Amongst Orthodontic Residents, Timothy Renison

Electronic Thesis and Dissertation Repository

Background: The cost of education to become an orthodontist has increased significantly over recent years which has led to an increase in debt of graduating orthodontists.

Aim: This paper aims to assess whether debt amongst orthodontic residents in North America is associated with their stress levels, attitudes towards debt, financial literacy and mathematics anxiety.

Materials and Methods: Web-based software was used to fabricate a questionnaire, based on previously validated scales, in which respondents were asked questions regarding their debt levels, stress levels, attitudes towards debt, financial literacy and math anxiety.

Results: A total of 101 orthodontic residents completed the online ...


The Role Of Panx3 In Age-Associated And Injury-Induced Intervertebral Disc Degeneration, Meaghan Serjeant, Paxton M. Moon, Diana Quinonez, Silvia Penuela, Frank Beier, Cheryle A. Séguin Feb 2021

The Role Of Panx3 In Age-Associated And Injury-Induced Intervertebral Disc Degeneration, Meaghan Serjeant, Paxton M. Moon, Diana Quinonez, Silvia Penuela, Frank Beier, Cheryle A. Séguin

Physiology and Pharmacology Publications

© 2021 by the authors. Licensee MDPI, Basel, Switzerland. Pannexin 3 (Panx3) is a mechanosensitive, channel-forming glycoprotein implicated in the progression of post-traumatic osteoarthritis. Despite evidence for Panx3 expression in the intervertebral disc (IVD), its function in this cartilaginous joint structure remained unknown. Using Panx3 knockout mice, this study investigated the role of Panx3 in age-associated IVD degeneration and degeneration induced by annulus fibrosus (AF) needle puncture. Loss of Panx3 did not significantly impact the progression of age-associated histopathological IVD degeneration; however, loss of Panx3 was associated with decreased gene expression of Acan, Col1a1, Mmp13 and Runx2 and altered localization of ...


Combined Medial Patellofemoral Ligament And Medial Patellotibial Ligament Reconstruction For Recurrent Lateral Patellar Dislocation In Flexion, Taher Abdelrahman, Gilbert Moatshe, Elizabeth Arendt, Julian Feller, Alan Getgood Feb 2021

Combined Medial Patellofemoral Ligament And Medial Patellotibial Ligament Reconstruction For Recurrent Lateral Patellar Dislocation In Flexion, Taher Abdelrahman, Gilbert Moatshe, Elizabeth Arendt, Julian Feller, Alan Getgood

Bone and Joint Institute

© 2020 Arthroscopy Association of North America Recurrent lateral patellar dislocation can be a challenging entity to manage. It results from an imbalance between the restraints to lateralization of the patella and the forces applied to the patella within the biomechanical environment of the knee. The medial patellofemoral ligament has been recognized as the most important static soft-tissue restraint. However, the medial patellotibial ligament and medial patellomeniscal ligament are important for patellar stability at higher degrees of knee flexion. Lateral patellar dislocation in flexion poses a particularly challenging clinical entity with a combination of unique characteristics that need to be addressed ...


Schrödinger Filtering: A Precise Eeg Despiking Technique For Eeg-Fmri Gradient Artifact, Gabriel B. Benigno, Ravi S. Menon, Hacene Serrai Feb 2021

Schrödinger Filtering: A Precise Eeg Despiking Technique For Eeg-Fmri Gradient Artifact, Gabriel B. Benigno, Ravi S. Menon, Hacene Serrai

Brain and Mind Institute Researchers' Publications

In EEG data acquired in the presence of fMRI, gradient-related spike artifacts contaminate the signal following the common preprocessing step of average artifact subtraction. Spike artifacts compromise EEG data quality since they overlap with the EEG signal in frequency, thereby confounding frequency-based inferences on activity. As well, spike artifacts can inflate or deflate correlations among time series, thereby confounding inferences on functional connectivity. We present Schrödinger filtering, which uses the Schrödinger equation to decompose the spike-containing input. The basis functions of the decomposition are localized and pulse-shaped, and selectively capture the various input peaks, with the spike components clustered at ...


Total Knee Replacement After High Tibial Osteotomy: Time-To-Event Analysis And Predictors, Codie A. Primeau, Trevor B. Birmingham, Kristyn M. Leitch, Kevin R. Willits, Robert B. Litchfield, Peter J. Fowler, Jacquelyn D. Marsh, Bert M. Chesworth, Stephanie N. Dixon, Dianne M. Bryant, J. Robert Giffin Feb 2021

Total Knee Replacement After High Tibial Osteotomy: Time-To-Event Analysis And Predictors, Codie A. Primeau, Trevor B. Birmingham, Kristyn M. Leitch, Kevin R. Willits, Robert B. Litchfield, Peter J. Fowler, Jacquelyn D. Marsh, Bert M. Chesworth, Stephanie N. Dixon, Dianne M. Bryant, J. Robert Giffin

Bone and Joint Institute

© 2021 Joule Inc. or its licensors. BACKGROUND: An important aim of high tibial osteotomy (HTO) is to prevent or delay the need for total knee replacement (TKR). We sought to estimate the frequency and timing of conversion from HTO to TKR and the factors associated with it. METHODS: We prospectively evaluated patients with osteoarthritis (OA) of the knee who underwent medial opening wedge HTO from 2002 to 2014 and analyzed the cumulative incidence of TKR in July 2019. The presence or absence of TKR on the HTO limb was identified from the orthopedic surgery reports and knee radiographs contained in ...