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2017

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Full-Text Articles in Medicine and Health Sciences

Exploring Incivility Among Nursing And Health Science Students: A Descriptive Study, Diane Louise Smith Dec 2017

Exploring Incivility Among Nursing And Health Science Students: A Descriptive Study, Diane Louise Smith

Student Theses, Dissertations and Capstones

Incivility has infiltrated our institutions of higher learning as well as the world of nursing. All too familiar in nursing is the phrase “eating their young,” which aptly describes how nurses treat other nurses, even though they should be nurturing and caring professionals.

The investigator explored nursing and health science students’ perceptions of student and faculty uncivil behaviors within the academic environment, seeking the levels and frequency of the problem. Bandura’s social learning theory presents a sound theoretical framework for this dissertation. The research methodology consisted of a quantitative descriptive approach. The Incivility in Higher Education-Revised (IHE-R) Survey was ...


Cardiorespiratory Fitness Is Inversely Associated With Clustering Of Metabolic Syndrome Risk Factors: The Ball State Adult Fitness Program Longitudinal Lifestyle Study, Elizabeth Kelley, Mary T. Imboden, Matthew P. Harber, Holmes Finch, Leonard A. Kaminsky, Mitchell H. Whaley Dec 2017

Cardiorespiratory Fitness Is Inversely Associated With Clustering Of Metabolic Syndrome Risk Factors: The Ball State Adult Fitness Program Longitudinal Lifestyle Study, Elizabeth Kelley, Mary T. Imboden, Matthew P. Harber, Holmes Finch, Leonard A. Kaminsky, Mitchell H. Whaley

Faculty Publications - Department of Health and Human Performance

Objective: The focus of this study was the association between the metabolic syndrome (MetSyn) and cardiorespiratory fitness (CRF) defined as maximal oxygen uptake (VO2max). Although previous research has shown a relationship between MetSyn and CRF, most studies are based on less objective measures of CRF and different cardiometabolic risk factor thresholds from earlier guidelines.


Incremental Dialysis For Preserving Residual Kidney Function—Does One Size Fit All When Initiating Dialysis?, A. T. Mathew, Y. Obi, C. M. Rhee, J. A. Chou, K. Kalantar-Zadeh Dec 2017

Incremental Dialysis For Preserving Residual Kidney Function—Does One Size Fit All When Initiating Dialysis?, A. T. Mathew, Y. Obi, C. M. Rhee, J. A. Chou, K. Kalantar-Zadeh

Journal Articles

© 2018 Wiley Periodicals, Inc. While many patients have substantial residual kidney function (RKF) when initiating hemodialysis (HD), most patients with end stage renal disease in the United States are initiated on 3-times per week conventional HD regimen, with little regard to RKF or patient preference. RKF is associated with many benefits including survival, volume control, solute clearance, and reduced inflammation. Several strategies have been recommended to preserve RKF after HD initiation, including an incremental approach to HD initiation. Incremental HD prescriptions are personalized to achieve adequate volume control and solute clearance with consideration to a patient's endogenous renal function ...


Effects Of Functional Electrical Stimulation Cycling Versus Cycling Only On Walking Performance And Quality Of Life In Individuals With Multiple Sclerosis: A Randomized, Clinical Pilot Study, Lori Hochman Dec 2017

Effects Of Functional Electrical Stimulation Cycling Versus Cycling Only On Walking Performance And Quality Of Life In Individuals With Multiple Sclerosis: A Randomized, Clinical Pilot Study, Lori Hochman

Department of Physical Therapy Student Theses, Dissertations and Capstones

Background: Functional Electrical Stimulation (FES) stimulates peripheral nerves via electrical current to evoke muscle contractions and when combined with lower extremity cycling (LE), creates patterned leg movements. Previous studies demonstrated FES cycling is safe and effective in the spinal cord injury and stroke populations with improvements seen in walking speed, muscle mass, and bone density. Few studies have applied FES cycling to a neurodegenerative disorder, such as multiple sclerosis (MS). The aim of this study is to assess the effect of an 8-week training program using FES cycling, compared to Cycling Only, in people with MS (PWMS). Methods: Using a ...


Evaluation Of Myplate Recommendations And Dietary Habits Of Eiu Rotc Cadets: A Mixed Methods Approach, Lilibeth Nevarez Dec 2017

Evaluation Of Myplate Recommendations And Dietary Habits Of Eiu Rotc Cadets: A Mixed Methods Approach, Lilibeth Nevarez

Masters Theses

The purpose of this study was to determine if MyPlate recommendation knowledge, dietary habits, and eating for performance influence the daily consumption among Eastern Illinois University ROTC Cadets. The sample population included EIU ROTC cadets (n=19), between the ages of 18 to 28 years old. A mixed-method approach, using a questionnaire along with focus groups interviews of six to ten cadets from all class levels, was used to obtain data. Results indicated that the highest mean score was 18.9 for MyPlate recommendation knowledge. In addition, five themes were analyzed: Inconsistency of dietary intake, High cost of eating healthy ...


Phase 1 Project Report. Social Networks And Norms: Sanitation In Bihar And Tamil Nadu, India, Cristina Bicchieri, Sania Ashraf, Upasak Das, Hans-Peter Kohler, Jinyi Kuang, Peter Mcnally, Alexey Shpenev, Erik Thulin Dec 2017

Phase 1 Project Report. Social Networks And Norms: Sanitation In Bihar And Tamil Nadu, India, Cristina Bicchieri, Sania Ashraf, Upasak Das, Hans-Peter Kohler, Jinyi Kuang, Peter Mcnally, Alexey Shpenev, Erik Thulin

Penn Social Norms Group (PennSoNG)

No abstract provided.


Intergenerational Financial Exchange And Cognitive Well-Being Among Older Adults In China, Ping Xu Dec 2017

Intergenerational Financial Exchange And Cognitive Well-Being Among Older Adults In China, Ping Xu

Graduate Doctoral Dissertations

Although cognitive loss is part of normal aging, it has unfavorable consequences for older individuals, their family, as well as society. The prevalence of mild cognition impairment is expected to go up in China. How to maintain normal cognition for a longer period of time and to delay impair process is an emerging concern for older Chinese adults. Unlike Western countries, China lacks of formal support system. Intergenerational support between older parents and adult children is a predominant resource when they are in need. This study examines how intergenerational financial exchanges between older parents and their adult children is related ...


Depression: The Often Overlooked Sequela Of Head Trauma, Samuel D. Hodge Jr., Jack E. Hubbard Dec 2017

Depression: The Often Overlooked Sequela Of Head Trauma, Samuel D. Hodge Jr., Jack E. Hubbard

Cleveland State Law Review

Depression is a common sequela of head trauma. Approximately half of all individuals with a cranial injury will experience depression within the first year, regardless of the severity of the injury. The ailment is characterized clinically as a mood disorder, often associated with intense feelings of sadness. However, depression is more complex than mood disorders, as many mental and bodily complaints—such as insomnia, fatigue, anxiety, appetite changes, aches and pains, and lack of interest in previously enjoyable activities—are associated with depression. These intense feelings, particularly when combined with despair and hopelessness, can lead to suicide, a dreaded potential ...


The Applicability Of The Decisional Conflict Scale In Nursing Home Placement Decision Among Chinese Family Caregivers: A Mixed Methods Approach, Yu-Ping Chang, Loralee Sessanna, Joanne Kraenzle Schneider Dec 2017

The Applicability Of The Decisional Conflict Scale In Nursing Home Placement Decision Among Chinese Family Caregivers: A Mixed Methods Approach, Yu-Ping Chang, Loralee Sessanna, Joanne Kraenzle Schneider

Asian/Pacific Island Nursing Journal

This study aimed to 1) examine relationships between uncertainty, perceived information, personal values, social support, and filial obligation among Chinese family caregivers faced with nursing home placement of an older adult family member with dementia; and 2) describe the applicability of the Decisional Conflict Scale in nursing home placement decision making among Chinese family caregivers through the integration of quantitative and qualitative data.

We used a mixed-methods approach. Quantitative data analysis consisted of descriptive and correlational statistics. We utilized a thematic analysis for the qualitative data. Data transformation and data comparison techniques were used to combine qualitative and quantitative data ...


Evaluation Of Extracellular Matrix Composition And Rheology As Determinants Of Growth, Invasion, And Response To Photodynamic Therapy In 3d Cell Culture Models Of Pancreatic Ductal Adenocarcinoma, Gwendolyn M. Cramer Dec 2017

Evaluation Of Extracellular Matrix Composition And Rheology As Determinants Of Growth, Invasion, And Response To Photodynamic Therapy In 3d Cell Culture Models Of Pancreatic Ductal Adenocarcinoma, Gwendolyn M. Cramer

Graduate Doctoral Dissertations

Pancreatic ductal adenocarcinoma (PDAC) is a notoriously lethal disease characterized by prominent stromal involvement, which plays complex roles in regulating tumor growth and therapeutic response. The extracellular matrix (ECM)-rich stroma has been implicated as a barrier to drug penetration, although stromal depletion strategies have had mixed clinical success. It remains less clear how biophysical interactions with the ECM regulate invasive progression and susceptibilities to specific therapies. Here, an integrative approach combining 3D cell culture and quantitative imaging techniques is used to evaluate invasive behavior and motility as determinants of response to classical chemotherapy and photodynamic therapy (PDT), in which ...


Research News. Grants, 2017. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar Dec 2017

Research News. Grants, 2017. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during July-December 2017


Effects Of 8 And 12 Hour Non-Rotating Shift Schedules For Security And Protective Services Workers, Zuleyha Aydin Dec 2017

Effects Of 8 And 12 Hour Non-Rotating Shift Schedules For Security And Protective Services Workers, Zuleyha Aydin

Theses

Shiftwork is a major feature of working life in today’s world. Increasing the workday length is a new trend in alternative work schedules. The features of a shift system operation can have an impact on sleep, alertness, and the well-being of shif


Computational And Experimental Determination Of The Mixing Efficiency Of A Microfluidic Serpentine Micromixer, Siril Arockiam Dec 2017

Computational And Experimental Determination Of The Mixing Efficiency Of A Microfluidic Serpentine Micromixer, Siril Arockiam

Theses

In microfluidics, efficiency and mixing time are the greatest disadvantages. These parameters hinder the application of microfluidic devices for biochemical and immunological assays. However, once these disadvantages have been overcome by optimizing th


Research News. Publications, 2017. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar Dec 2017

Research News. Publications, 2017. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period July 1 through December 31, 2017


Comparative Analysis Of The Dissolution Performance Of Aspirin Tablets In The Usp Apparatus 2 And In A Minivessel Dissolution System, Annmarie C. Walker Dec 2017

Comparative Analysis Of The Dissolution Performance Of Aspirin Tablets In The Usp Apparatus 2 And In A Minivessel Dissolution System, Annmarie C. Walker

Theses

Dissolution testing is a critical component of quality control procedures in the pharmaceutical industry in order to ensure that the final solid dosage forms have consistent dissolution properties. Dissolution tests are also routinely conducted to eval


Experiences Of Persons With Parkinson’S Disease Engaged In Group Therapeutic Singing, Elizabeth L. Stegemoller, Tera R. Hurt, Margaret C. Shirley, Randie D. Camp, Chrishelda W. Green, Jenna C. Pattee, Ebony Williams Dec 2017

Experiences Of Persons With Parkinson’S Disease Engaged In Group Therapeutic Singing, Elizabeth L. Stegemoller, Tera R. Hurt, Margaret C. Shirley, Randie D. Camp, Chrishelda W. Green, Jenna C. Pattee, Ebony Williams

Human Development and Family Studies Publications

Background Parkinson’s disease (PD) is a progressive neurodegenerative disorder that leads to altered neural control of movement, including the control of voice, respiration, and swallowing. There is a prevalent need to provide therapy for voice, respiration, and swallowing difficulties because current pharmacological and surgical treatments do not effectively treat these impairments. Previous research has demonstrated that singing may be a treatment option to target voice, respiratory, and swallowing impairments, as well as quality of life. However, participants’ perspectives related to reasons for enrolling and engaging in programs as well as evaluation of singing programs have been neglected.

Objective The ...


Molecular Characterization Of Multidrug-Resistant Klebsiella Pneumoniaeand Escherichia Coliharbouring Extended Spectrum Beta-Lactamases Andcarbapenemases Genes At A Tertiary Hospital, Kenya, Daniel Maina, Gunturu Revathi, Andrew C. Whitelaw Dec 2017

Molecular Characterization Of Multidrug-Resistant Klebsiella Pneumoniaeand Escherichia Coliharbouring Extended Spectrum Beta-Lactamases Andcarbapenemases Genes At A Tertiary Hospital, Kenya, Daniel Maina, Gunturu Revathi, Andrew C. Whitelaw

Pathology, East Africa

Background: Multidrug-resistant (MDR) Gram negative rods are increasingly being reported in sub-Saharan Africa. Molecular investigations play an important role, alongside other measures, in controlling nosocomial infections attributed to these organisms.

This study aimed to determine the common extended spectrum beta-lactamases (ESBL) and carbapenemases genes, and clonal relationship in MDR Klebsiella pneumoniae and Escherichia coli.

Methods: Fifty-four MDR isolates collected at the Aga Khan University hospital, Nairobi in the month of August 2012 formed the study. These were picked after an increase in the number of resistant strains during the said period was experienced.

Results: blaCTXM was present in 41 (74 ...


December 19 N (7).Mp3, Padmanaban Krishnan Dec 2017

December 19 N (7).Mp3, Padmanaban Krishnan

Padmanaban Krishnan

This is a radio interview conducted by Pam Geppert relating to end-use quality evaluation of wheat.


Discovery Of Novel, Orally Bioavailable, Antileishmanial Compounds Using Phenotypic Screening, Diana Ortiz, W. Armand Guiguemde, Jared T. Hammill, Angela K. Carrillo, Yizhe Chen, Michele Connelly, Kayla Stalheim, Carolyn Elya, Alex Johnson, Jaeki Min, Anang Shelat, David C. Smithson, Lei Yang, Fangyi Zhu, R. Kiplin Guy, Scott M. Landfear Dec 2017

Discovery Of Novel, Orally Bioavailable, Antileishmanial Compounds Using Phenotypic Screening, Diana Ortiz, W. Armand Guiguemde, Jared T. Hammill, Angela K. Carrillo, Yizhe Chen, Michele Connelly, Kayla Stalheim, Carolyn Elya, Alex Johnson, Jaeki Min, Anang Shelat, David C. Smithson, Lei Yang, Fangyi Zhu, R. Kiplin Guy, Scott M. Landfear

Pharmaceutical Sciences Faculty Publications

Leishmaniasis is a parasitic infection that afflicts approximately 12 million people worldwide. There are several limitations to the approved drug therapies for leishmaniasis, including moderate to severe toxicity, growing drug resistance, and the need for extended dosing. Moreover, miltefosine is currently the only orally available drug therapy for this infection. We addressed the pressing need for new therapies by pursuing a two-step phenotypic screen to discover novel, potent, and orally bioavailable antileishmanials. First, we conducted a high-throughput screen (HTS) of roughly 600,000 small molecules for growth inhibition against the promastigote form of the parasite life cycle using the nucleic ...


Ovarian Cancer Screening: Lessons About Effectiveness, Edward J. Pavlik Dec 2017

Ovarian Cancer Screening: Lessons About Effectiveness, Edward J. Pavlik

Obstetrics and Gynecology Faculty Publications

No abstract provided.


The Effect Of Rare Variants In Trem2 And Pld3 On Longitudinal Cognitive Function In The Wisconsin Registry For Alzheimer's Prevention, Corinne D. Engelman, Burcu F. Darst, Murat Bilgel, Eva Vasiljevic, Rebecca L. Koscik, Bruno M. Jedynak, Sterling C. Johnson Dec 2017

The Effect Of Rare Variants In Trem2 And Pld3 On Longitudinal Cognitive Function In The Wisconsin Registry For Alzheimer's Prevention, Corinne D. Engelman, Burcu F. Darst, Murat Bilgel, Eva Vasiljevic, Rebecca L. Koscik, Bruno M. Jedynak, Sterling C. Johnson

Mathematics and Statistics Faculty Publications and Presentations

Recent studies have found an association between functional variants in TREM2 and PLD3 and Alzheimer's disease (AD), but their effect on cognitive function is unknown. We examined the effect of these variants on cognitive function in 1449 participants from the Wisconsin Registry for Alzheimer's Prevention, a longitudinal study of initially asymptomatic adults, aged 36–73 years at baseline, enriched for a parental history of AD. A comprehensive cognitive test battery was performed at up to 5 visits. A factor analysis resulted in 6 cognitive factors that were standardized into z scores (∼N [0, 1]); the mean of these ...


Computer-Aided Drug Design Of Capuramycin Analogues As Anti-Tuberculosis Antibiotics By 3d-Qsar And Molecular Docking, Yuanyuan Jin, Shuai Fan, Guangxin Lv, Haoyi Meng, Zhengyang Sun, Wei Jiang, Steven G. Van Lanen, Zhaoyong Yang Dec 2017

Computer-Aided Drug Design Of Capuramycin Analogues As Anti-Tuberculosis Antibiotics By 3d-Qsar And Molecular Docking, Yuanyuan Jin, Shuai Fan, Guangxin Lv, Haoyi Meng, Zhengyang Sun, Wei Jiang, Steven G. Van Lanen, Zhaoyong Yang

Pharmaceutical Sciences Faculty Publications

Capuramycin and a few semisynthetic derivatives have shown potential as anti-tuberculosis antibiotics.To understand their mechanism of action and structureactivity relationships a 3D-QSAR and molecular docking studies were performed. A set of 52 capuramycin derivatives for the training set and 13 for the validation set was used. A highly predictive MFA model was obtained with crossvalidated q2 of 0.398, and non-cross validated partial least-squares (PLS) analysis showed a conventional r2 of 0.976 and r2pred of 0.839. The model has an excellent predictive ability. Combining the 3D-QSAR and molecular docking studies, a number of ...


Simulations For Designing And Interpreting Intervention Trials In Infectious Diseases., M Elizabeth Halloran, Kari Auranen, Sarah Baird, Nicole E Basta, Steven E Bellan, +Several Additional Authors Dec 2017

Simulations For Designing And Interpreting Intervention Trials In Infectious Diseases., M Elizabeth Halloran, Kari Auranen, Sarah Baird, Nicole E Basta, Steven E Bellan, +Several Additional Authors

Global Health Faculty Publications

BACKGROUND: Interventions in infectious diseases can have both direct effects on individuals who receive the intervention as well as indirect effects in the population. In addition, intervention combinations can have complex interactions at the population level, which are often difficult to adequately assess with standard study designs and analytical methods.

DISCUSSION: Herein, we urge the adoption of a new paradigm for the design and interpretation of intervention trials in infectious diseases, particularly with regard to emerging infectious diseases, one that more accurately reflects the dynamics of the transmission process. In an increasingly complex world, simulations can explicitly represent transmission dynamics ...


High-Resolution Physical Map For Chromosome 16q12.1-Q13, The Blau Syndrome Locus., Xiaoju Wang, Helena Kuivaniemi, Gina Bonavita, Charlene J Williams, Gerard Tromp Dec 2017

High-Resolution Physical Map For Chromosome 16q12.1-Q13, The Blau Syndrome Locus., Xiaoju Wang, Helena Kuivaniemi, Gina Bonavita, Charlene J Williams, Gerard Tromp

Charlene Williams

BACKGROUND: The Blau syndrome (MIM 186580), an autosomal dominant granulomatous disease, was previously mapped to chromosome 16p12-q21. However, inconsistent physical maps of the region and consequently an unknown order of microsatellite markers, hampered us from further refining the genetic locus for the Blau syndrome. To address this problem, we constructed our own high-resolution physical map for the Blau susceptibility region. RESULTS: We generated a high-resolution physical map that provides more than 90% coverage of a refined Blau susceptibility region. The map consists of four contigs of sequence tagged site-based bacterial artificial chromosomes with a total of 124 bacterial artificial chromosomes ...


P5l Mutation In Ank Results In An Increase In Extracellular Inorganic Pyrophosphate During Proliferation And Nonmineralizing Hypertrophy In Stably Transduced Atdc5 Cells, Raihana Zaka, David Stokes, Arnold S. Dion, Anna Kusnierz, Fei Han, Charlene J. Williams Dec 2017

P5l Mutation In Ank Results In An Increase In Extracellular Inorganic Pyrophosphate During Proliferation And Nonmineralizing Hypertrophy In Stably Transduced Atdc5 Cells, Raihana Zaka, David Stokes, Arnold S. Dion, Anna Kusnierz, Fei Han, Charlene J. Williams

Charlene Williams

Ank is a multipass transmembrane protein that regulates the cellular transport of inorganic pyrophosphate. In the progressive ankylosis (ank) mouse, a premature termination mutation at glutamic acid 440 results in a phenotype characterized by inappropriate deposition of basic calcium phosphate crystals in skeletal tissues. Mutations in the amino terminus of ANKH, the human homolog of Ank, result in familial calcium pyrophosphate dihydrate deposition disease. It has been hypothesized that these mutations result in a gain-of-function with respect to the elaboration of extracellular inorganic pyrophosphate. To explore this issue in a mineralization-competent system, we stably transduced ATDC5 cells with wild-type Ank ...


Alamat Klinik Aborsi Medan-Jual Obat Aborsi, Mutiara Klinik Dec 2017

Alamat Klinik Aborsi Medan-Jual Obat Aborsi, Mutiara Klinik

mutiara klinik

KLINIK ABORSI-JUAL OBAT ABORSI AMPUH-OBAT PENGGUGUR KANDUNGN-OBAT TELAT BULAN
klinik aborsi,obat aborsi,jual obat aborsi,cara menggugurkan kandungan. 
Kami beri jasa Aborsi dengan bantuan obat Cytotec melalui metode terpadu kami terbukti selama 3 tahun sejauh ini HANYA mampu mencapai keberhasilan aborsi sampai 97%. Tidak ada keberhasilan 100% atau mutlak karena ditentukan oleh beberapa parameter, kondisi badan setiap individu sengat berbeda satu sama lain. Tidak ada 1 pun orang di dunia ini bahkan pemenang NOBEL biologi sekalipun bisa menggaransi hasil dan reaksi yang sama persis pada setiap individu (tehnik sampling dan statistik), setiap obat yang diluncurkan di pasaran sudah melewati ...


Jual Forex Obat Kuat Herbal Di Magelang 085242284396 Cod, Cimoe Oke Dec 2017

Jual Forex Obat Kuat Herbal Di Magelang 085242284396 Cod, Cimoe Oke

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Jual Forex Obat Kuat Herbal Di Semarang 085242284396 Cod, Cimoe Oke Dec 2017

Jual Forex Obat Kuat Herbal Di Semarang 085242284396 Cod, Cimoe Oke

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ForexAdalah Obat Kuat Pembesar Penis No.1 Termanjur Terbaik di Indonesia Produk ForexAsli Obat Kuat Atau Suplemen Pembesar Penis Yang lagi Tenar Dan Di Buru OrangForex Salah Satu Produk dan 100% Tanpa Efek Samping Yang Telah Teruji Kliniks Terbukti guna Untuk Membantu Pria Dewasa Agar kembalikan Keperkasaan Walau Sudah Berumur 65 Tahun Sekalipun dan Formula Yang Telah di Uji Oleh Para Pakar Spesialis ...


Monosexual And Nonmonosexual Women In Same-Sex Couples’ Relationship Quality During The First Five Years Of Parenthood, Abbie E. Goldberg, Randi L. Garcia, Melissa H. Manley Dec 2017

Monosexual And Nonmonosexual Women In Same-Sex Couples’ Relationship Quality During The First Five Years Of Parenthood, Abbie E. Goldberg, Randi L. Garcia, Melissa H. Manley

Psychology: Faculty Publications

Research on relationship quality in same-sex couples has rarely focused on (1) couples who are parents, or (2) couples in which partners differ in sexual identity. Insomuch as nonmonosexual women (i.e., women with non-exclusive sexual orientations) experience unique challenges due to monosexism, relationship quality may be influenced by whether partners share a monosexual or nonmonosexual identity. The current study is a longitudinal, dyadic analysis of 118 female parents within 63 same-sex couples whose relationship quality (relationship maintenance, conflict, love, ambivalence) was assessed at five time points across the first 5 years of adoptive parenthood. Monosexual women were those who ...


Multicenter, Randomized Study To Optimize Bowel For Colon Capsule Endoscopy, David Kastenberg, Wilmot C. Burch Jr, David P. Romeo, Pankaj K. Kashyap, David C. Pound, Neophytos Papageorgiou, Ignacio Fernández-Urien Sainz, Carly E. Sokach, Douglas K. Rex Dec 2017

Multicenter, Randomized Study To Optimize Bowel For Colon Capsule Endoscopy, David Kastenberg, Wilmot C. Burch Jr, David P. Romeo, Pankaj K. Kashyap, David C. Pound, Neophytos Papageorgiou, Ignacio Fernández-Urien Sainz, Carly E. Sokach, Douglas K. Rex

Division of Gastroenterology and Hepatology Faculty Papers

AIM To assess the cleansing efficacy and safety of a new Colon capsule endoscopy (CCE) bowel preparation regimen. METHODS This was a multicenter, prospective, randomized, controlled study comparing two CCE regimens. Subjects were asymptomatic and average risk for colorectal cancer. The second generation CCE system (PillCam® COLON 2; Medtronic, Yoqneam, Israel) was utilized. Preparation regimens differed in the 1st and 2nd boosts with the Study regimen using oral sulfate solution (89 mL) with diatrizoate meglumine and diatrizoate sodium solution (“diatrizoate solution”) (boost 1 = 60 mL, boost 2 = 30 mL) and the Control regimen oral sulfate solution (89 mL ...