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Articles 1 - 30 of 64446

Full-Text Articles in Medicine and Health Sciences

Comparison Of Emla And Diclofenac On Reduction Of Pain And Phlebitis Caused By Peripheral Iv Catheter: A Randomized-Controlled Trial Study, Faezeh Babaieasl, Hossein Y. Yarandi, Seyedehtanaz Saeidzadeh, Motahareh Kheradmand Jan 2019

Comparison Of Emla And Diclofenac On Reduction Of Pain And Phlebitis Caused By Peripheral Iv Catheter: A Randomized-Controlled Trial Study, Faezeh Babaieasl, Hossein Y. Yarandi, Seyedehtanaz Saeidzadeh, Motahareh Kheradmand

Nursing Faculty Research Publications

Peripheral venous catheters (PVC) are often used to provide hydration, medications, and blood products when the length of therapy is expected to be less that one week. Pain and phlebitis are frequent complications of PVC. Diclofenac and EMLA have been used to minimize these adverse effects, however, conflicting results have been reported regarding which has better outcomes. This double-blind, randomized controlled trial was conducted to compare the efficacy of EMLA and Diclofenac (TDP) in attenuating PVC pain and phlebitis. The inpatient setting was chosen because of the higher frequency of PVC insertions, allowing for a sufficient sample size. One hundred ...


Doctor Of Health Science 2019, Nova Southeastern University Jan 2019

Doctor Of Health Science 2019, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


College Of Pharmacy 2019, Nova Southeastern University Jan 2019

College Of Pharmacy 2019, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Master Of Science In Anesthesia-Tampa, Nova Southeastern University Jan 2019

Master Of Science In Anesthesia-Tampa, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


College Of Health Care Sciences Audiology, Nova Southeastern University Jan 2019

College Of Health Care Sciences Audiology, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Occupational Therapy Fort Lauderdale 2019, Nova Southeastern University Jan 2019

Occupational Therapy Fort Lauderdale 2019, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Master Of Biomedical Sciences, Nova Southeastern University Jan 2019

Master Of Biomedical Sciences, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


College Of Optometry, Nova Southeastern University Jan 2019

College Of Optometry, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Master Of Health Science Online Program, Nova Southeastern University Jan 2019

Master Of Health Science Online Program, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Master Of Science In Anesthesia Fort Lauderdale, Nova Southeastern University Jan 2019

Master Of Science In Anesthesia Fort Lauderdale, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Master Of Health Science/Doctor Of Health Science, Nova Southeastern University Jan 2019

Master Of Health Science/Doctor Of Health Science, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Dr. Kiran C. Patel College Of Osteopathic Medicine Graduate Programs, Nova Southeastern University Jan 2019

Dr. Kiran C. Patel College Of Osteopathic Medicine Graduate Programs, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Physician Assistant Fort Lauderdale, Nova Southeastern University Jan 2019

Physician Assistant Fort Lauderdale, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Physician Assistant Fort Meyers, Nova Southeastern University Jan 2019

Physician Assistant Fort Meyers, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Physician Assistant Orlando, Nova Southeastern University Jan 2019

Physician Assistant Orlando, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Occupational Therapy Tampa, Nova Southeastern University Jan 2019

Occupational Therapy Tampa, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


College Of Dental Medicine 2019, Nova Southeastern University Jan 2019

College Of Dental Medicine 2019, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


Physician Assistant Jacksonville, Nova Southeastern University Jan 2019

Physician Assistant Jacksonville, Nova Southeastern University

Health Professions Divisions Course Catalogs

No abstract provided.


A Latent Spatial Piecewise Exponential Model For Interval-Censored Disease Surveillance Data With Time-Varying Covariates And Misclassification, Yaxuan Sun, Chong Wang, William Q. Meeker, Max Morris, Marisa L. Rotolo, Jeffery Zimmerman Jan 2019

A Latent Spatial Piecewise Exponential Model For Interval-Censored Disease Surveillance Data With Time-Varying Covariates And Misclassification, Yaxuan Sun, Chong Wang, William Q. Meeker, Max Morris, Marisa L. Rotolo, Jeffery Zimmerman

Veterinary Diagnostic and Production Animal Medicine Publications

Understanding the dynamics of disease spread is critical to achieving effective animal disease surveillance. A major challenge in modeling disease spread is the fact that the true disease status cannot be known with certainty due to the imperfect diagnostic sensitivity and specificity of the tests used to generate the disease surveillance data. Other challenges in modeling such data include interval censoring, relating disease spread to distance between units, and incorporating time-varying covariates, which are the unobserved disease statuses. We propose a latent spatial piecewise exponential model (PEX) with misclassification of events to address the challenges in modeling such disease surveillance ...


The Utilization Of Venous-Venous Extracorporeal Membrane Oxygenation Membrane For The Management Of Status Asthmaticus, Kenneth Miller Msrt, Med, Rrt-Accs, Faarc,, Jennifer Strow Do, Alison N. Bedekovich Msn, Rn Dec 2018

The Utilization Of Venous-Venous Extracorporeal Membrane Oxygenation Membrane For The Management Of Status Asthmaticus, Kenneth Miller Msrt, Med, Rrt-Accs, Faarc,, Jennifer Strow Do, Alison N. Bedekovich Msn, Rn

Patient Care Services / Nursing

No abstract provided.


11-06-18 Hsc Committee Meeting Minutes, Hsc Committee Dec 2018

11-06-18 Hsc Committee Meeting Minutes, Hsc Committee

HSC Committee (A subcommittee of the UNM Board of Regents)

No abstract provided.


The Use Of Milrinone In Neonates With Persistent Pulmonary Hypertension Of The Newborn - A Randomised Controlled Trial Pilot Study (Mint 1): Study Protocol And Review Of Literature., Afif F. El-Khuffash, Patrick J. Mcnamara, Colm Breatnach, Neidin Bussmann, Aisling Smith, Oliver Feeney, Elizabeth Tully, Joanna Griffin, Willem P. De Boode, Brian Cleary, Orla Franklin, Eugene Dempsey Dec 2018

The Use Of Milrinone In Neonates With Persistent Pulmonary Hypertension Of The Newborn - A Randomised Controlled Trial Pilot Study (Mint 1): Study Protocol And Review Of Literature., Afif F. El-Khuffash, Patrick J. Mcnamara, Colm Breatnach, Neidin Bussmann, Aisling Smith, Oliver Feeney, Elizabeth Tully, Joanna Griffin, Willem P. De Boode, Brian Cleary, Orla Franklin, Eugene Dempsey

Department of Paediatrics Articles

Persistent pulmonary hypertension of the newborn (PPHN) is a relatively common condition which results in a mortality of up to 33%. Up to 40% of infants treated with nitric oxide (iNO) either have a transient response or fail to demonstrate an improvement in oxygenation. Milrinone, a selective phosphodiesterase 3 (PDE3) inhibitor with inotropic and lusitropic properties may have potential benefit in PPHN. This pilot study was developed to assess the impact of milrinone administration on time spent on iNO in infants with PPHN. This is a multicentre, randomized, double-blind, two arm pilot study, with a balanced (1:1) allocation of ...


Pharmacist Interventions Involving Patient Outreach: Early Findings Of Patient Outcomes In Older Adults, Matthew Fair Bs, Pharmd, Bcps, Bcgp,, Michelle Omari-Okyere Bs, Pharmd, Bcps, Bcgp, Elie Jabbour Pharmd, Mba,, Brenda Frutos Mph, Ches, Nyann Biery Ms Dec 2018

Pharmacist Interventions Involving Patient Outreach: Early Findings Of Patient Outcomes In Older Adults, Matthew Fair Bs, Pharmd, Bcps, Bcgp,, Michelle Omari-Okyere Bs, Pharmd, Bcps, Bcgp, Elie Jabbour Pharmd, Mba,, Brenda Frutos Mph, Ches, Nyann Biery Ms

Department of Pharmacy

No abstract provided.


Resilience Training For Va Primary Care Providers, Elizabeth A. Recupero Dec 2018

Resilience Training For Va Primary Care Providers, Elizabeth A. Recupero

Instructional Design Capstones Collection

Physician burnout syndrome is epidemic within the U.S. healthcare system. Burnout is defined by three main criteria: emotional exhaustion, depersonalization, and a low sense of personal accomplishment, and its prevalence is highest among primary care providers. The VA’s All Employee Survey (AES) demonstrates that more than 50% of physicians working for the VA Healthcare System exhibit at least one of these symptoms. The literature discusses that this syndrome can be improved by increasing physician resilience. This capstone project first analyzed the need for resiliency training among VA primary care providers. After the needs analysis, an online training that ...


Design For Success: Identifying A Process For Transitioning To An Intensive Online Course Delivery Model In Health Professions Education., Paige L Mcdonald, Kenneth J Harwood, Joan T Butler, Karen S Schlumpf, Carson W Eschmann, Daniela Drago Dec 2018

Design For Success: Identifying A Process For Transitioning To An Intensive Online Course Delivery Model In Health Professions Education., Paige L Mcdonald, Kenneth J Harwood, Joan T Butler, Karen S Schlumpf, Carson W Eschmann, Daniela Drago

Clinical Research and Leadership Faculty Publications

Intensive courses (ICs), or accelerated courses, are gaining popularity in medical and health professions education, particularly as programs adopt e-learning models to negotiate challenges of flexibility, space, cost, and time. In 2014, the Department of Clinical Research and Leadership (CRL) at the George Washington University School of Medicine and Health Sciences began the process of transitioning two online 15-week graduate programs to an IC model. Within a year, a third program also transitioned to this model. A literature review yielded little guidance on the process of transitioning from 15-week, traditional models of delivery to IC models, particularly in online learning ...


Effect Of Differences In Metabolic Activity Of Melanoma Models On Response To Lonidamine Plus Doxorubicin., Kavindra Nath, Jeffrey Roman, David S. Nelson, Lili Guo, Seung-Cheol Lee, Stepan Orlovskiy, Kevin Muriuki, Daniel F. Heitjan, Stephen Pickup, Dennis B. Leeper, Ian A. Blair, Mary E. Putt, Jerry D. Glickson Dec 2018

Effect Of Differences In Metabolic Activity Of Melanoma Models On Response To Lonidamine Plus Doxorubicin., Kavindra Nath, Jeffrey Roman, David S. Nelson, Lili Guo, Seung-Cheol Lee, Stepan Orlovskiy, Kevin Muriuki, Daniel F. Heitjan, Stephen Pickup, Dennis B. Leeper, Ian A. Blair, Mary E. Putt, Jerry D. Glickson

Department of Radiation Oncology Faculty Papers

Lonidamine (LND), a metabolic modulator, sensitizes DB-1 human melanoma to doxorubicin (DOX) chemotherapy by acidifying and de-energizing the tumor. This report compares the effects of LND on two human melanoma lines, DB-1 and WM983B, which exhibit different metabolic properties. Using liquid chromatography mass spectrometry and Seahorse analysis, we show that DB-1 was more glycolytic than WM983B in vitro. 31P magnetic resonance spectroscopy (MRS) indicates that LND (100 mg/kg, i.p.) induces similar selective acidification and de-energization of WM983B xenografts in immunosuppressed mice. Over three hours, intracellular pH (pHi) of WM983B decreased from 6.91 ± 0.03 to 6 ...


Levels Of Par-1 Kinase Determine The Localization Of Bruchpilot At The Drosophila Neuromuscular Junction Synapses., Kara R. Barber, Martin Hruska, Keegan M. Bush, Jade A. Martinez, Hong Fei, Irwin B. Levitan, Matthew B. Dalva, Yogesh P. Wairkar Dec 2018

Levels Of Par-1 Kinase Determine The Localization Of Bruchpilot At The Drosophila Neuromuscular Junction Synapses., Kara R. Barber, Martin Hruska, Keegan M. Bush, Jade A. Martinez, Hong Fei, Irwin B. Levitan, Matthew B. Dalva, Yogesh P. Wairkar

Farber Institute for Neurosciences Faculty Papers

Functional synaptic networks are compromised in many neurodevelopmental and neurodegenerative diseases. While the mechanisms of axonal transport and localization of synaptic vesicles and mitochondria are relatively well studied, little is known about the mechanisms that regulate the localization of proteins that localize to active zones. Recent finding suggests that mechanisms involved in transporting proteins destined to active zones are distinct from those that transport synaptic vesicles or mitochondria. Here we report that localization of BRP-an essential active zone scaffolding protein in Drosophila, depends on the precise balance of neuronal Par-1 kinase. Disruption of Par-1 levels leads to excess accumulation of ...


Characterization Of Antibiotic Use For Acute Otitis Media In Pediatric Physician Practices, Jasica N. Truong Pharmd, Kristin M. Held Pharmd, Bcop, Jennifer E. Macfarlan Mph, Tibisay Villalobos Md, Faap Dec 2018

Characterization Of Antibiotic Use For Acute Otitis Media In Pediatric Physician Practices, Jasica N. Truong Pharmd, Kristin M. Held Pharmd, Bcop, Jennifer E. Macfarlan Mph, Tibisay Villalobos Md, Faap

Department of Pharmacy

No abstract provided.


Retrospective Analysis Of Guideline Recommended Antiretroviral Regimens And Vaccination Schedules For Adult Patients With Human Immunodeficiency Virus (Hiv) In An Infectious Diseases Clinic, Jose A. Roman Pharmd, Jarrod W. Kile Rph, Bcps, Amy Slenker Md, Hope Kincaid Mph, Cph Dec 2018

Retrospective Analysis Of Guideline Recommended Antiretroviral Regimens And Vaccination Schedules For Adult Patients With Human Immunodeficiency Virus (Hiv) In An Infectious Diseases Clinic, Jose A. Roman Pharmd, Jarrod W. Kile Rph, Bcps, Amy Slenker Md, Hope Kincaid Mph, Cph

Department of Pharmacy

No abstract provided.


Loss-Of-Function Mutations In Atp6ap1 And Atp6ap2 In Granular Cell Tumors., Fresia Pareja, Alissa H. Brandes, Thais Basili, Pier Selenica, Felipe C. Geyer, Dan Fan, Arnaud Da Cruz Paula, Rahul Kumar, David N. Brown, Rodrigo Gularte-Mérida, Barbara Alemar, Rui Bi, Raymond S. Lim, Ino De Bruijn, Sho Fujisawa, Rui Gardner, Elvin Feng, Anqi Li, Edaise M. Da Silva, John R. Lozada, Pedro Blecua, Leona Cohen-Gould, Achim A. Jungbluth, Emad A. Rakha, Ian O. Ellis, Maria I.A. Edelweiss, Juan P. Palazzo, Larry Norton, Travis Hollmann, Marcia Edelweiss, Brian P. Rubin, Britta Weigelt, Jorge S. Reis-Filho Dec 2018

Loss-Of-Function Mutations In Atp6ap1 And Atp6ap2 In Granular Cell Tumors., Fresia Pareja, Alissa H. Brandes, Thais Basili, Pier Selenica, Felipe C. Geyer, Dan Fan, Arnaud Da Cruz Paula, Rahul Kumar, David N. Brown, Rodrigo Gularte-Mérida, Barbara Alemar, Rui Bi, Raymond S. Lim, Ino De Bruijn, Sho Fujisawa, Rui Gardner, Elvin Feng, Anqi Li, Edaise M. Da Silva, John R. Lozada, Pedro Blecua, Leona Cohen-Gould, Achim A. Jungbluth, Emad A. Rakha, Ian O. Ellis, Maria I.A. Edelweiss, Juan P. Palazzo, Larry Norton, Travis Hollmann, Marcia Edelweiss, Brian P. Rubin, Britta Weigelt, Jorge S. Reis-Filho

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Granular cell tumors (GCTs) are rare tumors that can arise in multiple anatomical locations, and are characterized by abundant intracytoplasmic granules. The genetic drivers of GCTs are currently unknown. Here, we apply whole-exome sequencing and targeted sequencing analysis to reveal mutually exclusive, clonal, inactivating somatic mutations in the endosomal pH regulators ATP6AP1 or ATP6AP2 in 72% of GCTs. Silencing of these genes in vitro results in impaired vesicle acidification, redistribution of endosomal compartments, and accumulation of intracytoplasmic granules, recapitulating the cardinal phenotypic characteristics of GCTs and providing a novel genotypic-phenotypic correlation. In addition, depletion of ATP6AP1 or ATP6AP2 results in ...