Medicine and Health Sciences Commons^™

Influence Of Beta And Theta Waves As Predictors Of Simple And Complex Reaction Times In Examined Groups Of Judo Athletes During The Vienna Test, Magdalena Pronczuk, Tomasz Chamera, Alicja Markiel, Jerzy Markowski, Jan Pilch, Piotr Żmijewski, Adam Maszczyk

Baltic Journal of Health and Physical Activity

Introduction: This research aimed to investigate which waves, Theta or Beta, are significant predictors of visual simple and complex reaction times during the Vienna test, using regression modeling. The research material comprised the test results of male judo athletes (n = 24), selected through mixed sampling (purposive and random). The study was conducted in two cycles, differentiated by frequency but with the same duration of EEG biofeedback sessions, in both the control and experimental groups. The first cycle of the study consisted of 15 sessions held every other day. Each training session lasted for 4 minutes. The second series …

The Effectiveness Of Resistance Exercises Performed On Stable And Unstable Surfaces In Relation To Torso Activation, Radim Jebavy, Dusan Blazek, Helena Vomackova, Jan Vavra, Jan Busta, Anna Pisz, Petr Stastny

Baltic Journal of Health and Physical Activity

Introduction: Deep stabilization system (DSS) strength and endurance are crucial for injury prevention and athletic performance. Training surfaces can influence training outcomes; therefore, this study aimed to compare the impact of performing strength trunk exercises on unstable and stable surfaces with conventional trunk exercises. Materials and Methods: DSS and trunk stability were assessed before and after 10 weeks of three different training interventions among twenty elite futsal players. Each intervention included 25 strength training sessions. Pre- and post-tests encompassed various measurements, including diaphragm, trunk flexion, trunk back extension, hip flexion, intraabdominal pressure, side plank, pronation, and supination tests. Results: Conventional …

Tracing Antibacterial Compounds From Kaledang (Artocarpus Lanceifolius Roxb.) Stem Bark, Hamsidar Hasan, Tety Tuloli, Syamsul Bahri, La Ode Aman

Pharmaceutical Sciences and Research

Artocarpus lanceifolius Roxb. or kaledang is a species of the mulberry family, Moraceae. Several extracts from its family have been reported to have antibacterial activity. Thus, it is necessary to determine compounds that have nature as antibacterial to be raw materials for antibacterial herbal medicines. The purpose of the study was to trace compounds that have antibacterial activity from Artocarpus lanceifolius stem bark. The study method was extraction by graded maceration, fractionation with column vacuum chromatography (CVC), isolation by radial chromatography, determination of antibacterial activity by agar diffusion method using the Gram positive and Gram negative bacteria. The characterization …

Changes In Perceptions Of First Responders After Witnessing A Drug Overdose: Individual And Contextual Variations Among People Who Use Opioids In West Virginia, Kathleen L. Egan, Kelly Gurka, Alexandria Macmadu, Herb Linn

Journal of Appalachian Health

Introduction: Success of opioid overdose interventions involving first responders is dependent on the comfort level that bystanders have with first responders and their willingness to call for assistance. Positive or negative experiences with first responders following witnessing an overdose may influence a person’s willingness to call a first responder for assistance in the future.

Purpose: The objective of this study was to examine changes in bystanders’ perceptions of first responders following witnessing an overdose attended by emergency medical services or a law enforcement official. It specifically explored perception changes among a sample of individuals residing in Appalachia who use prescription …

Disparities In Mortality Between Appalachian And Non-Appalachian Regions Of Kentucky, Sonali S. Salunkhe, Sahal Alzahrani, Beatrice Ugiliweneza

Journal of Appalachian Health

Introduction: In the opioid epidemic, the U.S. faces a significant public health crisis, with some areas of the country, such as rural and Appalachian regions, suffering more than others. The differential regional impact of the crisis in Kentucky—a state with both non-metropolitan/metropolitan and Appalachian/Non-Appalachian statuses—has not yet been documented despite such knowledge being essential to the success of overdose prevention efforts.

Purpose: This study compares all-cause, drug- and opioid-related mortality between counties in different regions of Kentucky: Appalachian non-metropolitan, Appalachian metropolitan, non-Appalachian non-metropolitan, and non-Appalachian metropolitan.

Methods: Age-adjusted mortality data from the Centers for Disease Control and Prevention’s Wide-ranging Online …

Assessing And Addressing The Determinants Of Appalachian Population Health: A Scoping Review, David L. Driscoll, Hannah O'Donnell, Maitri Patel, David C. Cattell-Gordon

Journal of Appalachian Health

Introduction: Residents of Appalachia experience elevated rates of morbidity and mortality compared to national averages, and these disparities are associated with inequitable exposures to various determinants of population health. Social and environmental determinants of health are a useful lens through which to develop and evaluate programs to mitigate regional health disparities.

Methods: This 2023 scoping review was conducted of studies linking determinants of Appalachian health with leading causes of regional mortality and morbidity. The search strategy employed a keyword search that included geographic terms for the Appalachian Region and the primary adverse health outcomes in that region. Studies meeting the …

A Suspected Case Of Levetiracetam Induced Rhabdomyolysis, Luke Merrill Ms, Layne Hohn Ms, Marlee Jones Ms, Sydney Gibson Ms, Ty Moody Md, Anthony Breemo Md

Aesculapius Journal (Health Sciences & Medicine)

Background: Levetiracetam is a broad-spectrum antiseizure drug which works to terminate convulsions and is used in the treatment of certain types of seizures. It is commonly used to treat epilepsy in adults, and has proven an effective treatment for adults with focal seizures. This drug is normally well tolerated, but commonly reported adverse effects include fatigue, somnolence, and dizziness. A few less common effects have been noted as well, including behavioral disturbances, thrombocytopenia, and—in very few cases—rhabdomyolysis.

Case Report: Our case reports a 55-year-old male who presented to a rural emergency department for active convulsing and unresponsiveness. Initial …

Carbapenem-Resistant Enterobacterales—Kentucky, 2013–2020: Challenges And Successes, Mary Issac, Andrea Flinchum, Kevin Spicer

Journal of Appalachian Health

Introduction: Carbapenem-resistant Enterobacterales (CRE) are considered urgent, antibiotic-resistant threats in the U.S. and are of global concern. Active collaboration between public health authorities and healthcare facilities and providers will be necessary to prevent and contain these organisms.

Purpose: To describe the epidemiology of CRE in Kentucky and to discuss challenges and successes with building and sustaining an effective prevention and containment program.

Methods: Retrospective descriptive summary of CRE isolates reported by healthcare providers, facilities, and laboratories in Kentucky from 2013 through 2020. Data available from case reporting forms and laboratory testing are summarized.

Results: From 2013 through 2020, 1805 CRE …

A Rare Occurrence Of Ectopic Parathyroid Carcinoma Presenting As A Case Of Recurrent Fractures, Saad Bin Zafar Mahmood, Aisha Jamal, Zain Mushtaq, Qamar Masood

Section of Internal Medicine

Ectopic parathyroid tumors are uncommon, accounting for only 6% of parathyroid adenomas, and even fewer cases are attributed to parathyroid carcinomas. While ectopic parathyroid carcinoma in the anterior mediastinum is a rare condition, the occurrence of recurrent skeletal fractures in the presence of mild hypercalcemia is even rarer. In this report, we present the case of a 52-year-old man with a medical history of hypertension, chronic kidney disease, and a previous right-sided intertrochanteric fracture of the femur one year earlier. He presented to the emergency room with left-sided hip pain and shortness of breath due to volume overload. Laboratory tests …

Kombinasi Sofosbuvir-Ledipasvir Dan Sofosbuvir- Daclatasvir Pada Pengobatan Pasien Hepatitis C Di Indonesia, Andri Sanityoso Sulaiman Dr, Irsan Hasan Dr, Cosmas Rinaldi Adithya Lesmana Dr, Juferdy Kurniawan Dr, Gita Aprilicia, Yayah Nugroho Dr, Nunuk Tri Wahyuni Dr, Budiman Sujatmika Sulaiman

Jurnal Penyakit Dalam Indonesia

Introduction. Direct-acting antivirals (DAAs) has been developed for treatment hepatitis C virus (HCV). Therapy of HCV using DAA has shown high sustained virologic response (SVR) and shortening duration of therapy. Sofosbuvir-ledipasvir (SOF/LDV) is fixed dose combination tablet of DAAs which recommended for genotype 1, 4, 5, and 6 infected patients. In developing countries, SOF/LDV still can be used as cost-effective regimen in all genotype compared with sofosbuvir-daclatasvir (SOF/ DCV). This study aimed to evaluate the efficacy of combination sofosbuvir-ledipasvir in all genotypes of HCV patients compared with available DAA in Indonesia (sofosbuvir- daclatasvir).

Methods. A retrospective study was …

Survei Kebutuhan Edukasi Pasien Lupus Eritematosus Sistemik, Jennifer Josephine, Alvina Widhani, Rahmat Cahyanur, Teguh Harjono Karjadi

Jurnal Penyakit Dalam Indonesia

Introduction. Patients with systemic lupus erythematosus (SLE) who suffer from chronic illness, need tailored education to better manage their condition. As nowadays education through internet and social media contributes significantly. This study aimed to assess internet usage related to lupus, educational needs, and education sources preferences among patients.

Methods. This study was a cross-sectional study conducted on adult SLE patients at Allergy and Clinical Immunology Clinic, Internal Medicine Department, Cipto Mangunkusumo Hospital, Jakarta, between July-August 2023. Respondents completed a set of questionnaires regarding their internet usage related to lupus, education platform preferences, and educational needs assessment tool (ENAT). …

Review Of: Coal, Cages, Crisis: The Rise Of The Prison Economy In Central Appalachia, Ted Olson Phd

Journal of Appalachian Health

Ted Olson, PhD, is a professor of both Appalachian Studies and Bluegrass, Old-Time and Roots Music Studies at East Tennessee State University. In this piece, he reviews Professor Judah Schept's Coal, Cages, Crisis: The Rise of the Prison Economy in Central Appalachia and discusses the impacts of incarceration on the health of Appalachia and on its residents more broadly.

Modifikasi Skor Timi Sebagai Model Prediksi Mortalitas 30 Hari Pasien Stemi Muda, M. Tasrif Mansur, Muhammad Yamin, Lusiani Rusdi, Murdani Abdullah, Birry Karim, Cleopas Martin Rumende, Maruhum Bonar H. Marbun, Hamzah Shatri

Jurnal Penyakit Dalam Indonesia

Introduction. Cardiovascular disease is a leading cause of death worldwide. Three-quarters of these deaths occur in lowand middle-income countries among individuals in their productive years. ST-segment elevation myocardial infarction (STEMI) is a dangerous manifestation of coronary artery disease (CAD) and can lead to sudden death. Smoking and a family history of early CAD are major risk factors for STEMI cases. However, their role in any risk stratification system for patients has not been clearly established. The most widely used score in assessing the prognosis of STEMI patients is the TIMI score, but its accuracy in the young patient population …

Penyakit Sel Sabit Pada Pasien Laki-Laki Berusia 27 Tahun Yang Sebelumnya Didiagnosis Sebagai Talasemia: Sebuah Laporan Kasus, Rahmat Cahyanur, Andree Kurniawan, Ratuafni Sharfina, Nadia Ayu Mulansari

Jurnal Penyakit Dalam Indonesia

Sickle cell disease (SCD) is a hemoglobinopathy inherited in an autosomal recessive pattern arising from a mutation causing substitution of valine for glutamic acid in the sixth amino acid of the β-globin chain. The clinical manifestation of SCD varies from acute pain, chronic anemia, to multi-organ infarct and failure. SCD is known to be rare in Indonesia. However, we recently encountered a SCD patient presenting with recurrent pain and hypesthesia since a year ago. The diagnosis of SCD in this patient was established based on the results of peripheral blood smear and hemoglobin electrophoresis. The patient had previously been diagnosed …

Smart Missions That Enable Innovation In High-Risk Environments., Ed Hoffman

Level 3

This article is a lightly edited version of Ed Hoffman’s talk on to the 01-June-2023 seminar hosted by the PRST entitled ICH Q9(R1): The Next Frontier – An audience with international thought leaders exploring how the effective use of knowledge can enhance QRM outcomes to benefit the patient. Ed’s remarks are focused on the future of work, and the needs for relationships, storytelling, and understanding the mission to get the best out of our collective intelligence and navigate the future of work.

Novel Anti-Influenza Monoclonal Antibodies, Ozlem Gurses

NYMC Student Theses and Dissertations

There is a continual public threat of influenza virus infections. This is related to viruses evolving in multiple animal reservoirs, making infection prevention in humans difficult to achieve and leading to seasonal epidemics and the semi-regular emergence of pandemics. Novel antibody-based therapies are of great interest to researchers because of a dramatic increase in drug resistant strains of influenza viruses. The identification of cross-reactive and broadly protective monoclonal antibodies targeting the influenza proteins presents a promising prospect for the development of a universal therapy. Although the research related to the monoclonal antibodies targeting the viral internal proteins is limited, multiple …

Uji Coba Pemberian Snack Bars Berbahan Dasar Tape Ketan Hitam Sebagai Sumber Serat Terhadap Penurunan Kadar Glukosa Darah Puasa Pasien Diabetes Melitus Tipe 2, Muhammad Muayyad Billah, Budiyanti Wiboworini, Adi Prayitno

Jurnal Penyakit Dalam Indonesia

Introduction. Managing dietary pattern, including snack schedule, is one of the most important factors in maintaining blood glucose levels in patients with type 2 diabetes mellitus (T2DM). Black glutinous rice tape is one of the foods that contains bioactive nutrient and fiber beneficial to health. This study aimed to determine the effect of snack bars made from black glutinous rice tape on fasting blood glucose levels in T2DM patients.

Methods. The study employed a quasi-experimental pre and post-test design with a control group which was conducted among T2DM patients undergoing treatment at Bhayangkara Tk. II Sartika Asih Hospital, …

Pentingnya Edukasi Pasien Lupus Eritematosus Sistemik, Evy Yunihastuti, Fadlika Harinda

Jurnal Penyakit Dalam Indonesia

Lupus eritematosus sistemik (LES) merupakan penyakit kronik yang dapat mengenai berbagai macam organ dengan manifestasi ringan hingga serius. Karakteristik LES adalah sangat dinamis, bervariasi, dengan perjalanan penyakit yang kadang tidak dapat diprediksi. Walau saat ini semakin tinggi pengetahuan tentang patofisiologi, optimalisasi penanganan, dan banyak ditemukan obat yang lebih baik untuk terapi LES, masih banyak ODAPUS (orang dengan lupus) mengalami morbiditas, mortalitas, dan kualitas hidup yang kurang baik. Tanpa penanganan yang baik, pemantauan dan pengobatan yang teratur, tentu luaran yang baik akan lebih sulit didapatkan.

Efektivitas Sacubitril/Valsartan Dalam Mencegah Gagal Jantung Pada Stemi Pasca Percutaneous Coronary Intervention, Nobian Andre, Lana Adila, Aulia Rizka, Lusiani Rusdi

Jurnal Penyakit Dalam Indonesia

Heart failure is a possible complication following ST-elevation myocardial infarction (STEMI) even after revascularization. Neuroendocrine activation in the process of ventricular remodeling can be regulated by angiotensin receptor-neprilysin inhibitor (ARNI) as well as angiotensin-converting enzyme (ACE) inhibitor. The use of ARNI in heart failure with reduced ejection fraction has been found to be superior to ACE inhibitor. The role of ARNI on cardiac function in STEMI has not been established. A clinician treating a patient with STEMI considered giving sacubitril/valsartan to reduce the risk of developing heart failure. Literature search was performed in three electronic databases: PubMed, Embase, and Cochrane. …

Antimicrobial Activity Of Crude Fractions Of Gossypium Barbadense Leaves And Isolation Of Stigmasterol, Maryam Saddiq, Ahmed Salisu, Kamaluddeen Kabir, Yusuf Hassan

Pharmaceutical Sciences and Research

Plants have been used in traditional medicine in different parts of the world to treat several diseases. Many studies have confirmed their medicinal values, which have led to the isolation and characterization of various potential drug candidates. This study focuses on the antimicrobial activity of crude fractions of Gossypium barbadense leaves and the isolation of active compound. The pulverized plant leave was soaked in ethanol (98% v/v), and a solvent-based fractionation was carried out using n-hexane, chloroform, ethyl acetate, and ethanol. The obtained crude fractions were screened for antimicrobial activity against four (4) clinical isolates: Escherichia coli, Pseudomonas …

Angka Kejadian Dan Karakteristik Klinis Pasien Infeksi Jamur Invasif Di Rsup Dr. Hasan Sadikin Tahun 2020 – 2022, Ariella Alessandro, Nisa Fauziah, Imam Megantara, Rudi Wisaksana, Intan Mauli Warma Dewi

Jurnal Penyakit Dalam Indonesia

Introduction. Invasive fungal infection (IFI) is increasingly common in patients at risk, especially those with impaired immune response. In Indonesia, there is currently a low prevalence of IFI which may be influenced by challenges in diagnosis. This study aimed to determine the prevalence and clinical characteristics of IFI patients in Dr. Hasan Sadikin Hospital in Bandung, Indonesia.

Methods. This cross-sectional study was conducted at Dr. Hasan Sadikin Hospital. Data were collected using medical records of IFI patients diagnosed between 2020 and 2022 which were selected using total sampling method. Demographic data, clinical symptoms, radiological appearance, and laboratory results …

Konsep Diagnosis Dan Penatalaksanaan Fraktur Osteoporosis Terkini, I Gusti Ngurah Wien Aryana, Febyan Febyan

Jurnal Penyakit Dalam Indonesia

Osteoporosis is a metabolic bone disease that is caused by a decreased amount of bone mass, and microarchitectural damage to bone tissue that affects the bone to break easily. Osteoporosis can be divided into primary and secondary etiologies. Vertebral, hip, distal radius, and proximal humerus are the most common predilection of fracture complication due to osteoporosis. The diagnosis of osteoporotic fractures is established based on the identification of risk factors, general clinical manifestations, specific manifestation from each fracture predilection, and advanced examinations, including radiology imaging and dual-energy x-ray absorptiometry. The purpose of osteoporotic fractures management in elderly is a stable …

Tandem Walking Exercise To Improve Cognitive Function In The Elderly, I Made Dhita Prianthara, Iga Sri Wahyuni Novianti, I Putu Prisa Jaya, Ni Putu Diah Anantari, Ni Kadek Yuni Fridayani

Jurnal Keolahragaan

Decreased cognitive function in the elderly is the leading cause of inability to carry out normal daily activities, as well as a high level of reliance on others in caring for themselves. The many problems that arise due to decreased cognitive function require a healthy aging process so that decreased cognitive function does not cause health problems in the lives of the elderly. Decreased cognitive function in the elderly is the biggest cause of inability to carry out normal daily activities and is also the cause of the elderly experiencing a high level of dependence on others in caring for …

Literature Review: Nutrition Supplementation For Muscle Fatigue In Athletes, Mardiana Mardiana, Apoina Kartini, Dwi Sutiningsih, Suroto Suroto, Muhammad Solihuddin Muhtar

Jurnal Keolahragaan

The use of natural or conventional-based supplementation has become a popular strategy among athletes seeking to reduce oxidative stress, improve recovery, and enhance athletic performance. This literature review searched four reputable international electronic databases, including PubMed, MedRxiv, Cochrane, and Clinical Trial.gov until December 2021, using Boolean operators with keywords and Mesh methods. The keywords used were "Supplementation", AND "Muscle Fatigue Recovery", AND "Athletes", which yielded 24 articles as study findings. The literature review found that exhaustive exercise can induce a neutrophil antioxidant response by increasing antioxidant enzymes. Nutritional supplements, specifically antioxidant supplements, Branched Chain Amino Acid (BCAA), citrulline, omega-3, and …

Ameliorative Effects Of Fmrfamide On 3,4-Methylenedioxyl-Methamphetamine/Tramadol-Induced Neurodegeneration In The Hippocampus, O. E. Ogunbiyi, K. O. Adeniji, L. Arietarhire, P. Okwute, D. Abaneme, J. I. Enya, O. Soremekun, M. Adekunle, O. Soyinka, S. T. Adelodun, S. Y. Olatunji, T. Afolabi, T. P. Ajibade, A. G. Obaoye, M. Dada, Joshua Owolabi, John A. Olanrewaju

PCOM Scholarly Papers

Objective: Tramadol and 3,4-methylenedioxy-methamphetamine (MDMA) use over an extended period is linked to deficits in memory encoding and retrieval. We aimed to determine the neurotoxic effects of co-administration of MDMA and tramadol (TRAM) on hippocampal function and investigate the potential of FMRFamide in attenuating resulting alterations in the Wistar rat model. Methods: Thirty adult male Wistar rats were grouped into six (n=5): Control, FMRFamide, TRAM, MDMA, TRAM+MDMA, and TRAM + MDMA + FMRFamide groups. The opiates were administered orally at 20mg/kg each, while 2mg/kg of FMRFamide was administered intraperitoneally for 12 days using normal saline as a vehicle. The Barnes …

High-Risk Individuals And Naloxone Use: Implications For Thn Programs In Rural Appalachian Communities, Victor Garcia, Lisa Mccann, Erick Lauber, Christian Vaccaro, Melissa Swauger, Alex Daniel Heckert

Journal of Appalachian Health

Introduction: Take-home naloxone (THN) is being made available across rural Appalachia to curb opioid overdose fatalities. Despite this initiative, some opioid users do not possess naloxone, and if they do, do not administer it to others.

Purpose: Research findings on risk factors that contribute to opioid overdose are presented. These factors, identified in a sample of 16 overdose cases, are (1) early onset age of opioid use; (2) progressive opioid use; (3) a transition from pain medication to heroin and fentanyl; (4) fears of being arrested at a naloxone intervention if first responders are contacted, and (5) limited knowledge of …

Factors Associated With Covid-19 Vaccine Hesitancy In South Central Appalachia, Florence M. Weierbach, Rebecca Adkins Fletcher, Ingrid E. Luffman, Cynthia Meyer, Janet M. Keener, Manik Ahuja, Hadii M. Mamudu

Journal of Appalachian Health

Introduction: The newly emergent COVID-19 virus reached pandemic levels in March 2020. By the middle of August 2020, there were over 1 million deaths attributed to COVID-19 in the U.S., with those in rural areas outpacing urban counterparts. Prior to emergency approval of the Pfizer, Moderna and Johnson & Johnson vaccine formulations, mitigation efforts addressing individual behavior were challenging. However, even with the entrance of these three new vaccines, herd immunity was not achieved in rural areas, as vaccine uptake remained low there. Although there has since been an abundance of COVID-19-related research addressing health literacy, vaccine hesitancy and overall …

How To Know If A Journal Is Legitimate, Nancy Pearl Solomon

International Journal of Orofacial Myology and Myofunctional Therapy

In these times of quickly proliferating journals with potentially unscrupulous publishing practices, it is more important than ever to be confident that the journals you rely on for scholarly content and for your own publication needs are legitimate. We are proud to report that the IJOM was thoroughly reviewed by the Committee on Publication Ethics and has been accepted for membership, verifying that the journal maintains a commitment to research and a high level of publication integrity.

Efektivitas Step Marching Exercise Dalam Mengurangi Resiko Jatuh Pada Lansia, Jabbar Naufal Ramdhetya Mr., Ida Ayu Astiti Suadnyana Ms., Iga Sri Wahyuni Novianti Ms., I Gusti Ngurah Mayun Mr.

Jurnal Fisioterapi Terapan Indonesia or Indonesian Journal of Applied Physiotherapy

As age progresses, the elderly will experience a degenerative process which one of the impacts will cause a decrease in the ability to maintain balance in the elderly so that it will increase the risk of falling. To overcome this risk, it is necessary to give exercises to improve balance and muscle strength in lower extremity, one of which is step marching exercise. This exercise has alternating leg lifting movements by following a rhythm or beat. The purpose of this study was to determine the effectiveness of step marching exercise in reducing the risk of falls in the elderly. Method: …

Indeks Massa Tubuh Dan Obesitas Sentral Kaitannya Dengan Tekanan Darah Pada Anggota Batalyon X, Annisa Kusumarahmawati Ms., Farahdina Bachtiar Ms., Rena Mailani Ms., Andy Sirada Mr.

Jurnal Fisioterapi Terapan Indonesia or Indonesian Journal of Applied Physiotherapy

A sedentary lifestyle leading to obesity is one of the contributing factors to high blood pressure. Excessive fat can result in tissue dysfunction and is a key factor in the development of hypertension. Military personnel are expected to maintain good health and physical fitness. This study aimed to investigate the connection between Body Mass Index (BMI), central obesity, and blood pressure (BP) among Battalion X members. Methodology: A cross-sectional quantitative approach was employed with a sample size of 62 individuals. The data included height, weight, and waist circumference of the participants. Spearman's rho test was used for data analysis. The …