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Full-Text Articles in Medicine and Health Sciences

Validation Of A Method For Pantoprazole And Its Sulfone Metabolite In Goat Plasma Using High Performance Liquid Chromatography, Sherry Cox, Lainey Harvill, Sarah Bullock, Joseph Smith, Joan Bergman Nov 2022

Validation Of A Method For Pantoprazole And Its Sulfone Metabolite In Goat Plasma Using High Performance Liquid Chromatography, Sherry Cox, Lainey Harvill, Sarah Bullock, Joseph Smith, Joan Bergman

Faculty Publications and Other Works -- Large Animal Clinical Sciences

No abstract provided.


Learning To Automate Follow-Up Question Generation Using Process Knowledge For Depression Triage On Reddit Posts, Shrey Gupta, Anmol Agarwal, Manas Gaur, Kaushik Roy, Vignesh Narayanan, Ponnurangam Kumaraguru, Amit Sheth Oct 2022

Learning To Automate Follow-Up Question Generation Using Process Knowledge For Depression Triage On Reddit Posts, Shrey Gupta, Anmol Agarwal, Manas Gaur, Kaushik Roy, Vignesh Narayanan, Ponnurangam Kumaraguru, Amit Sheth

Publications

Conversational Agents (CAs) powered with deep language models (DLMs) have shown tremendous promise in the domain of mental health. Prominently, the CAs have been used to provide informational or therapeutic services (e.g., cognitive behavioral therapy) to patients. However, the utility of CAs to assist in mental health triaging has not been explored in the existing work as it requires a controlled generation of follow-up questions (FQs), which are often initiated and guided by the mental health professionals (MHPs) in clinical settings. In the context of `depression', our experiments show that DLMs coupled with process knowledge in a mental health ...


Overview Of The Clpsych 2022 Shared Task: Capturing Moments Of Change In Longitudinal User Posts, Adam Tsakalidis, Jenny Chim, Iman Munire Bilal, Ayah Zirikly, Dana Atzil-Slonim, Federico Nanni, Philip Resnik, Manas Gaur, Kaushik Roy, Becky Inkster, Jeff Leintz, Maria Liakata Oct 2022

Overview Of The Clpsych 2022 Shared Task: Capturing Moments Of Change In Longitudinal User Posts, Adam Tsakalidis, Jenny Chim, Iman Munire Bilal, Ayah Zirikly, Dana Atzil-Slonim, Federico Nanni, Philip Resnik, Manas Gaur, Kaushik Roy, Becky Inkster, Jeff Leintz, Maria Liakata

Publications

We provide an overview of the CLPsych 2022 Shared Task, which focusses on the automatic identification of Moments of Change in longitudinal posts by individuals on social media and its connection with information regarding mental health . This year's task introduced the notion of longitudinal modelling of the text generated by an individual online over time, along with appropriate temporally sensitive evaluation metrics. The Shared Task consisted of two subtasks: (a) the main task of capturing changes in an individual's mood (drastic changes-`Switches'- and gradual changes -`Escalations'- on the basis of textual content shared online; and subsequently (b ...


In Vivo Efficacy Of Pyrantel Pamoate As A Post-Exposure Prophylactic For Rat Lungworm (Angiostrongylus Cantonensis), John Jacob, Argon Steel, Lisa Kaluna, Steven Hess, Israel Leinbach, Carmen Antaky, Robert Sugihara, Lindsey Hamilton, Peter Follett, Kathleen Howe, Steven Jacquier, Supakit Wongwiwatthananukit, Susan Jarvi Aug 2022

In Vivo Efficacy Of Pyrantel Pamoate As A Post-Exposure Prophylactic For Rat Lungworm (Angiostrongylus Cantonensis), John Jacob, Argon Steel, Lisa Kaluna, Steven Hess, Israel Leinbach, Carmen Antaky, Robert Sugihara, Lindsey Hamilton, Peter Follett, Kathleen Howe, Steven Jacquier, Supakit Wongwiwatthananukit, Susan Jarvi

USDA Wildlife Services - Staff Publications

Rat lungworm (Angiostrongylus cantonensis) is a neurotropic nematode, and the leading cause of eosinophilic meningitis worldwide. The parasite is usually contracted through ingestion of infected gastropods, often hidden in raw or partially cooked produce. Pharmaceutical grade pyrantel pamoate was evaluated as a post-exposure prophylactic against A. cantonensis. Pyrantel pamoate is readily available over-the-counter in most pharmacies in the USA and possesses anthelmintic activity exclusive to the gastrointestinal tract (GIT). Administering pyrantel pamoate immediately after exposure should theoretically paralyze the larvae in the GIT, causing the larvae to be expelled via peristalsis without entering the systemic circulation. In this study, pyrantel ...


Rainbow Perfect And Near-Perfect Matchings In Complete Graphs With Edges Colored By Circular Distance, Shuhei Saitoh, Naoki Matsumoto, Wei Wu Jun 2022

Rainbow Perfect And Near-Perfect Matchings In Complete Graphs With Edges Colored By Circular Distance, Shuhei Saitoh, Naoki Matsumoto, Wei Wu

Theory and Applications of Graphs

Given an edge-colored complete graph Kn on n vertices, a perfect (respectively, near-perfect) matching M in Kn with an even (respectively, odd) number of vertices is rainbow if all edges have distinct colors. In this paper, we consider an edge coloring of Kn by circular distance, and we denote the resulting complete graph by Kn. We show that when Kn has an even number of vertices, it contains a rainbow perfect matching if and only if n=8k or n=8k+2, where k is a nonnegative integer. In the case of an odd number ...


Enhancing Vanadium Redox Battery Performance Using Tungsten-Bismuth-Based Oxide Nanostructures As Electrode Modifiers, Taher Al Najjar Jun 2022

Enhancing Vanadium Redox Battery Performance Using Tungsten-Bismuth-Based Oxide Nanostructures As Electrode Modifiers, Taher Al Najjar

Theses and Dissertations

Renewable energy power plants require high efficiency conversion and storage systems that can store high amounts of energy and can be integrated with the electrical grid. Vanadium redox flow batteries are very promising for this application. However, one major drawback of VRFBs is their low power density which means that right now they cannot replace non-renewable energy sources. Different carbon materials are used as electrodes in VRFBs and each carbon material affects the battery’s performance in a different way. Modification of these electrodes can increase the power density of the battery. Some metal oxides like tungsten oxide can enhance ...


A Simplified Model For The Intermediate Structure Of Strong Fire Whirls, Forman A. Williams Jun 2022

A Simplified Model For The Intermediate Structure Of Strong Fire Whirls, Forman A. Williams

Progress in Scale Modeling, an International Journal

A model is described for the overall structure of intense fire whirls, based on a spatially evolving vortex, with circulation enhancement driven by the axial acceleration of low-density gas in the core through the axial pressure gradient. The axial acceleration increases the entrainment rate into the core which, through mass conservation, increases the circulation if the angle between the tangential and radial velocity components remains fixed. The two-zone model employs general balance equations for regions inside and outside a cylinder of fixed radius, each inviscid, the inside region being presumed to have a constant density small compared with the (constant ...


Managing Risk And Knowledge: Frameworks To Guide Knowledge-Enabled Technology Transfer, Martin Lipa Dr, Anne Greene Jun 2022

Managing Risk And Knowledge: Frameworks To Guide Knowledge-Enabled Technology Transfer, Martin Lipa Dr, Anne Greene

Level 3

Technology transfer is not only about the transfer of technology, but also about the transfer of knowledge, as evidenced by definitions of KM within the biopharma industry and beyond. However, knowledge transfer is often not well structured and its effectiveness – in particular for tacit knowledge (i.e., know how) – is an opportunity for improvement which can lead to many benefits. This article profiles recent research into the topic of improving knowledge transfer during technology transfer and presents several recently developed frameworks for improving such. The article furthermore explains how the frameworks can be co-deployed in support of robust knowledge transfer ...


Emerging Technologies: Empowering People To Capture, Share And Transfer Tacit Knowledge, Donncadh J. Nagle, Melanie J. Adams Jun 2022

Emerging Technologies: Empowering People To Capture, Share And Transfer Tacit Knowledge, Donncadh J. Nagle, Melanie J. Adams

Level 3

ICH Q10 was published in 2008, and presented a model for an effective Pharmaceutical Quality System (PQS). However, the industry still has some way to go in embracing and implementing its principles in order to achieve greater product realisation, to establish and maintain a state of control, and to facilitate continual improvement.

ICH Q10 introduced us to two key enablers: Knowledge Management (KM) and Quality Risk Management (QRM).[1] While the pharmaceutical industry has made progress in implementing the principles of QRM since 2008, there has been significantly slower progress in implementing knowledge management practices. However, there may be solutions ...


Steps Towards Digital Transformation In The Pharmaceutical Manufacturing Landscape Knowledge-Enabled Technology Transfer, Anne Greene Professor, Martin Lipa Dr Jun 2022

Steps Towards Digital Transformation In The Pharmaceutical Manufacturing Landscape Knowledge-Enabled Technology Transfer, Anne Greene Professor, Martin Lipa Dr

Level 3

No abstract provided.


Stereocontrolled Access To Δ-Lactone-Fused-Γ-Lactams Bearing Angular Benzylic Quaternary Stereocenters, Timothy K. Beng, Morgan J. Rodriguez, Claire Borg Jun 2022

Stereocontrolled Access To Δ-Lactone-Fused-Γ-Lactams Bearing Angular Benzylic Quaternary Stereocenters, Timothy K. Beng, Morgan J. Rodriguez, Claire Borg

All Faculty Scholarship for the College of the Sciences

C-fused γ-lactam-lactones are resident in several bioactive molecules, including anticancer agents such as omuralide. In this embodiment, we report mild conditions for the catalytic halolactonization of lactam-tethered 5-aryl-4(E)-pentenoic acids. The use of dichloromethane as the solvent and Ph3PS as the catalyst led to predominant 6-endo-trig cyclization and furnished the trans-fused-γ-lactam-δ-lactones. The transformation is modular, regioselective, chemoselective, and diastereoselective. The γ-lactam-δ-lactones bear angular quaternary benzylic stereocenters, which is noteworthy since the presence of a quaternary carbon in bioactive small molecules often promotes an element of conformational restriction that imparts potency, selectivity, and metabolic stability. The ...


The Short-Term Effects Of Fine Airborne Particulate Matter And Climate On Covid-19 Disease Dynamics, El Hussain Shamsa, Kezhong Zhang Jun 2022

The Short-Term Effects Of Fine Airborne Particulate Matter And Climate On Covid-19 Disease Dynamics, El Hussain Shamsa, Kezhong Zhang

Medical Student Research Symposium

Background: Despite more than 60% of the United States population being fully vaccinated, COVID-19 cases continue to spike in a temporal pattern. These patterns in COVID-19 incidence and mortality may be linked to short-term changes in environmental factors.

Methods: Nationwide, county-wise measurements for COVID-19 cases and deaths, fine-airborne particulate matter (PM2.5), and maximum temperature were obtained from March 20, 2020 to March 20, 2021. Multivariate Linear Regression was used to analyze the association between environmental factors and COVID-19 incidence and mortality rates in each season. Negative Binomial Regression was used to analyze daily fluctuations of COVID-19 cases and ...


Reduced-Scale Experiments And Numerical Simulations Of Informal Settlement Dwelling Fires, Vigneshwaran Narayanan, Antonio Cicicone, Ayden D. Botha, Richard Shaun Walls Jun 2022

Reduced-Scale Experiments And Numerical Simulations Of Informal Settlement Dwelling Fires, Vigneshwaran Narayanan, Antonio Cicicone, Ayden D. Botha, Richard Shaun Walls

Progress in Scale Modeling, an International Journal

Informal settlement dwellings (ISDs) house approximately one billion people in the developing world and this number is expected to double by the year 2030. Contemporary research on ISD fires has focused on understanding the fire dynamics within individual dwellings (micro-scale) and fire spread in settlements consisting of multiple dwellings (macro-scale). This paper aims to do two primary things: investigate if scaling methods that were derived for compartments with thermally thick boundaries can be applied to ISDs (compartments with thermally thin boundaries), and if they can adequately represent the most important phenomena associated with full-scale ISD fires; and demonstrate Fire Dynamics ...


Data-Driven Analysis Of Drug And Substance Abuse Rates Across The Varying Regions In The United States Of America, Reem Saleh Jun 2022

Data-Driven Analysis Of Drug And Substance Abuse Rates Across The Varying Regions In The United States Of America, Reem Saleh

University Honors Theses

Drugs and substance abuse is one of the leading causes of death for adolescents in the United States. The consequences of using these drugs are profound and can cause both damage to one's physical and psychological health. The rates of drug abuse in the United States continue to increase over the years. This paper analyzes the trends in rates of drug abuse in the four regions in the United States. It looks at the rates in cocaine, cigarettes, marijuana, and tobacco. A preliminary analysis was done to look at the trend in rates followed by an ARIMA time series ...


Segmentation Of Infant Brain Using Nonnegative Matrix Factorization, Norah Saleh Alghamdi, Fatma Taher, Heba Kandil, Ahmed Sharafeldeen, Ahmed Elnakib, Ahmed Soliman, Yaser Elnakieb, Ali Mahmoud, Mohammed Ghazal, Ayman El-Baz May 2022

Segmentation Of Infant Brain Using Nonnegative Matrix Factorization, Norah Saleh Alghamdi, Fatma Taher, Heba Kandil, Ahmed Sharafeldeen, Ahmed Elnakib, Ahmed Soliman, Yaser Elnakieb, Ali Mahmoud, Mohammed Ghazal, Ayman El-Baz

All Works

This study develops an atlas-based automated framework for segmenting infants' brains from magnetic resonance imaging (MRI). For the accurate segmentation of different structures of an infant's brain at the isointense age (6-12 months), our framework integrates features of diffusion tensor imaging (DTI) (e.g., the fractional anisotropy (FA)). A brain diffusion tensor (DT) image and its region map are considered samples of a Markov-Gibbs random field (MGRF) that jointly models visual appearance, shape, and spatial homogeneity of a goal structure. The visual appearance is modeled with an empirical distribution of the probability of the DTI features, fused by their ...


Raytheon Technologies Corporation: An Analysis Of Leadership, Ethics, And Social Responsibility, Jarett Monterio May 2022

Raytheon Technologies Corporation: An Analysis Of Leadership, Ethics, And Social Responsibility, Jarett Monterio

Journal of Global Awareness

The purpose of this analysis is to examine Raytheon Technologies Corporation (RTC) in the context of its leadership structure, ethical issues and practices, stakeholder relationships, and position within the social responsibility realm. Undertaking an analysis of an aerospace and defense company such as RTC is perhaps timelier than ever. We live in a world of increasing global competition and confrontation. Simultaneously, we are experiencing unprecedented technological development. Combined, this has created a situation where the boundaries of conventional warfare have been redrawn. The questions of what appropriate offensive and defensive tactics are and how governments, and increasingly private sector companies ...


Contextualizing The Impact Of Faculty-Led Short-Term Study Abroad On Students’ Global Competence: Characteristics Of Effective Programs, Colleen Fisher, Laurel Iverson Hitchcock, Ashley Neyer, Stacy C. Moak, Sarah Moore, Scott Marsalis May 2022

Contextualizing The Impact Of Faculty-Led Short-Term Study Abroad On Students’ Global Competence: Characteristics Of Effective Programs, Colleen Fisher, Laurel Iverson Hitchcock, Ashley Neyer, Stacy C. Moak, Sarah Moore, Scott Marsalis

Journal of Global Awareness

Short-term faculty-led study abroad programs are high-impact pedagogical practices designed to enhance students' global competency. However, there is a gap in our understanding regarding the specific educational components of short-term faculty-led study abroad programs that promote global competency. This systematic review examined nearly two decades of research on such programs (n=86) to assess the educational components associated with increases in students' global competencies using Steinberg's (2017) educational components as a framework. Results indicated that the educational components included in global competency-building education abroad courses varied substantially across programs and global regions. The components most strongly supporting enhanced global ...


Notes From The Editor, Jay Nathan May 2022

Notes From The Editor, Jay Nathan

Journal of Global Awareness

No abstract provided.


Female Sex Offenders: Double Standards, Sofia Enes May 2022

Female Sex Offenders: Double Standards, Sofia Enes

Kean Quest

This paper will discuss female pedophiles, rapists, and sex offenders, also known as female sex criminals, the double standards, of how they are viewed in the criminal justice system, how the medical fields view them, the psychological effects of their actions on their victims, and how the public views them. Unlike male pedophiles, rapists, and sex offenders of that gender; female pedophiles are not as readily identified as male pedophiles. Since female sex criminals do not always conform and fit the stereotypes that are more commonly found in male sex criminals, it is much more difficult for authorities to detain ...


How Environmental Change Will Impact Mosquito-Borne Diseases, Arsal Khan May 2022

How Environmental Change Will Impact Mosquito-Borne Diseases, Arsal Khan

Master's Projects and Capstones

Mosquitos, the most lethal species throughout human history, are the most prevalent source of vector-borne diseases and therefore a major global health burden. Mosquito-borne disease incidence is expected to shift with environmental change. These changes can be predicted using species distribution models. With the wide variety of methods used for models, consensus for improving accuracy and comparability is needed. A comparative analysis of three recent modeling approaches revealed that integrating modeling techniques compensates for trade-offs associated with a singular approach. An area that represents a critical gap in our ability to predict mosquito behavior in response to changing climate factors ...


Accessing The Ecosphere: An Indoor Nature-Based Community Expressive Arts Therapy (Exat) Exploration Project, Heather Powers May 2022

Accessing The Ecosphere: An Indoor Nature-Based Community Expressive Arts Therapy (Exat) Exploration Project, Heather Powers

Expressive Therapies Capstone Theses

This capstone thesis posits that when humans connect and maintain a relationship with nature, their mental health improves. Humans have developed from and within Earth’s ecosystem, making our relationship with nature a necessary acknowledgement that the self is more than a corporeal body but is, in fact, embedded within the natural world around us. The current overwhelming dependence on electronic advancements and the development of urban areas have led people to become more distant in their relationship to nature, putting the overall well-being of the planet in jeopardy. This thesis points out that the more separation we feel from ...


Boxed Lunches, Lunch May 2022

Boxed Lunches, Lunch

Biology and Medicine Through Mathematics Conference

No abstract provided.


In-Phantom Film Measurements Of Two Treatment Planning Systems For Single-Fraction Spine Sbrt, Michael J. Taylor May 2022

In-Phantom Film Measurements Of Two Treatment Planning Systems For Single-Fraction Spine Sbrt, Michael J. Taylor

LSU Master's Theses

Purpose: Treatment planning accuracy for spine stereotactic body radiation therapy (SBRT) varies depending on the dose calculation algorithm utilized in the treatment planning system (TPS). This project compared the end-to-end accuracy between spine SBRT plans calculated in a convolution-superposition based TPS (TPSCS) and Monte Carlo based TPS (TPSMC) with radiochromic film measurements. The hypothesis was that TPSMC would calculate the dose gradient in the critical region between the vertebral body and the spinal cord more accurately than TPSCS.

Methods: Single-fraction spine SBRT treatments following RTOG 0631 and local institutional guidelines were planned in TPSCS and ...


Mathematics Of A Single-Locus Model For Assessing The Impacts Of Pyrethroid Resistance And Temperature On Population Abundance Of Malaria Mosquitoes, Jemal Mohammed-Awel May 2022

Mathematics Of A Single-Locus Model For Assessing The Impacts Of Pyrethroid Resistance And Temperature On Population Abundance Of Malaria Mosquitoes, Jemal Mohammed-Awel

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling Acute And Chronic Vascular Adaptations To A Major Arterial Occlusion, Erin O. Zhao May 2022

Modeling Acute And Chronic Vascular Adaptations To A Major Arterial Occlusion, Erin O. Zhao

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Model Of Subthalamic Nucleus Neuron - Characteristic Activity Patterns And Bifurcation Analysis, Choongseok Park, Sungwoo Ahn, Leonid Rubchinsky May 2022

Mathematical Model Of Subthalamic Nucleus Neuron - Characteristic Activity Patterns And Bifurcation Analysis, Choongseok Park, Sungwoo Ahn, Leonid Rubchinsky

Biology and Medicine Through Mathematics Conference

No abstract provided.


Modeling The Dynamics Of Usutu Virus Infection In Birds, Nora G. Heitzman-Breen May 2022

Modeling The Dynamics Of Usutu Virus Infection In Birds, Nora G. Heitzman-Breen

Biology and Medicine Through Mathematics Conference

No abstract provided.


Epidemiological Assessment Of Wolbachia-Based Biocontrol For Reduction Of Dengue Morbidity, Olga Vasilieva, Oscar E. Escobar, Hector J. Martinez, Pierre-Alexandre Bliman, Yves Dumont May 2022

Epidemiological Assessment Of Wolbachia-Based Biocontrol For Reduction Of Dengue Morbidity, Olga Vasilieva, Oscar E. Escobar, Hector J. Martinez, Pierre-Alexandre Bliman, Yves Dumont

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mechanical Parameters Fitting For Layer-Reduced Umbilical Arteries Used For Grafting, Kun Gou May 2022

Mechanical Parameters Fitting For Layer-Reduced Umbilical Arteries Used For Grafting, Kun Gou

Biology and Medicine Through Mathematics Conference

No abstract provided.


Mathematical Model Of Triple-Negative Breast Cancer In Response To Combination Chemotherapies, Angelica Davenport, Yun Lu, Carlos Gallegos, Adriana Massicano, Katherine Heinzman, Patrick Song, Anna Sorace, Nick Cogan May 2022

Mathematical Model Of Triple-Negative Breast Cancer In Response To Combination Chemotherapies, Angelica Davenport, Yun Lu, Carlos Gallegos, Adriana Massicano, Katherine Heinzman, Patrick Song, Anna Sorace, Nick Cogan

Biology and Medicine Through Mathematics Conference

No abstract provided.