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Medicine and Health Sciences Commons

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Thomas Jefferson University

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Articles 1 - 30 of 1997

Full-Text Articles in Medicine and Health Sciences

Download Entire Issue: Gibbon Surgical Review, Volume 1, Issue 2, 2018 Nov 2018

Download Entire Issue: Gibbon Surgical Review, Volume 1, Issue 2, 2018

Gibbon Surgical Review

Download Entire Issue: Gibbon Surgical Review, Volume 1, Number 2, 2018


Happy Mind, Bailey Bourgeois, Erica Jacobs, Allison Wisneski, Amanda Torres, Antii Makkonen Sep 2018

Happy Mind, Bailey Bourgeois, Erica Jacobs, Allison Wisneski, Amanda Torres, Antii Makkonen

Nexus Maximus

Center City is home to a vast majority of overworked 30 year old's with limited social lives and high stress levels which causes mental depletion and higher anxiety. Our solution to this problem is a mindfulness app for mobile phones that this specific group can participate in. The app would not only give you advice on your commute to work, but also give you invites to nearby social events and discounts to a number of stores in the area.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the ...


Fresh Express, Timothy Skill, Alaina Mclhenney, Minji Hong, Chinmay Joshi, Witali Brianzew, Abby Garrity, Taegun Park Sep 2018

Fresh Express, Timothy Skill, Alaina Mclhenney, Minji Hong, Chinmay Joshi, Witali Brianzew, Abby Garrity, Taegun Park

Nexus Maximus

Our project culminated with the decision to create Fresh Express. We began the project searching to find the best way to help end food insecurity in Philadelphia but specifically in Center City. Our food truck solution will help to create a healthier lifestyle for those directly in Center City and eventually throughout all of Philadelphia.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to ...


Growing Garden, Stan Kim, Lon'yea Ellis, Rhouleisha Thompson, Kristen Tekel Sep 2018

Growing Garden, Stan Kim, Lon'yea Ellis, Rhouleisha Thompson, Kristen Tekel

Nexus Maximus

To make space efficient garden system to have more green spaces through out the area.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend.

Teams will also explore opportunities to leverage that data in meaningful ways that benefit and protect individuals and society. The team project work will be supplemented with workshops on innovation, entrepreneurship, and ...


A Bag For A Bag, Nahye Kim, Gahyun Kim, Jasmyne Chester, Teagen Hay Sep 2018

A Bag For A Bag, Nahye Kim, Gahyun Kim, Jasmyne Chester, Teagen Hay

Nexus Maximus

A sustainable self-sufficiency cycle for the homeless population in Kensington suffering from food insecurity and beyond.

The problem of food insecurity of the homeless will be improved, while increasing level of the public hygiene, sense of community, and self-sufficiency extent of the homeless beyond basic survival needs.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend ...


What's Cooking?, Jake Isaac, Jessica Overpeck, Alisha Chacko, Kristina Kosztyo, Tuomas Tapper Sep 2018

What's Cooking?, Jake Isaac, Jessica Overpeck, Alisha Chacko, Kristina Kosztyo, Tuomas Tapper

Nexus Maximus

We decided to focus on a mobile solution to food insecurity and food deserts in Lower North Philadelphia. The approach will use education, cooking, and access to affordable whole foods. We created a business model for our mobile solution and this included many aspects, such as the problem, statistics, the solution, key partners, key activities, cost structure, revenue streams, future plans, etc.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops ...


Lnp Mediators For Posterity, Yinelia De La Cruz, Stephen Adasonla, Kieara Martin, Yi Soo Hahm, Jaymi Phillips, Holly Spring Sep 2018

Lnp Mediators For Posterity, Yinelia De La Cruz, Stephen Adasonla, Kieara Martin, Yi Soo Hahm, Jaymi Phillips, Holly Spring

Nexus Maximus

We have decided to tackle substance abuse in Lower North Philadelphia by eliminating the stigma around mental health in low income communities. By preventing drug usage in teen and young adult mental awareness, we can combat issues like suicide and the opioid epidemic. Using mediators by partnering with university students we can offer positive role models into the school system, while also offering internships and residency opportunities.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work ...


New Life, Madison Cotellese, Jahkiya Jack, Devaughn Lambert, Hammad Chaudhry, Mardochee Mallory Sep 2018

New Life, Madison Cotellese, Jahkiya Jack, Devaughn Lambert, Hammad Chaudhry, Mardochee Mallory

Nexus Maximus

Our final project is a drug rehabilitation facility in South Philadelphia. It highlights the problems of current facilities and proposes solutions to them.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend.

Teams will also explore opportunities to leverage that data in meaningful ways that benefit and protect individuals and society. The team project work will ...


Success In The Streets Of Kensington, Melanie Perkins, Lindsay Wratcher, Halie Finke, Friederike Stock Sep 2018

Success In The Streets Of Kensington, Melanie Perkins, Lindsay Wratcher, Halie Finke, Friederike Stock

Nexus Maximus

The third day of Nexus Maximus was spent working on our poster and getting our final ideas together to present the pitch to our audience. We all worked side by side in one of the DEC classrooms working on putting our thoughts into bullet points and developing the graphics for the board. My group member and I went to the poster workshop and got inspired to create the board layout. We wanted to keep the board as simple as possible with easy to read graphics and bullet points so that the viewer could easily follow our process and understand what ...


Cross Like A Boss, Ezana Ceman, Madeleine Scuderi, Brandi Davis, Syming Cottrell, Aryna Lysak Sep 2018

Cross Like A Boss, Ezana Ceman, Madeleine Scuderi, Brandi Davis, Syming Cottrell, Aryna Lysak

Nexus Maximus

"Cross Like a Boss" is an innovative solution to addressing pedestrian safety in South Philadelphia through policy changes. Included in the campaign is an RFID chip scanner card located at every major pedestrian crash hotspot which (1) allows users such as older adults, persons with disabilities, and children to have longer time crossing the street and (2) turn on audio options saying the word "Walk" in different languages corresponding to the major demographics of South Philadelphia. In addition, our new crosswalk policies involve a button for LED flashing lights along the crosswalk which alerts drivers in advance that there is ...


Fish Bowl, Joseph Goggin, James Fang, Sam Orente, Jessica Horton, Alyssa Milione Sep 2018

Fish Bowl, Joseph Goggin, James Fang, Sam Orente, Jessica Horton, Alyssa Milione

Nexus Maximus

Our idea was to try to bring the people of Fishtown together by hosting events that appeal to all ages.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend.

Teams will also explore opportunities to leverage that data in meaningful ways that benefit and protect individuals and society. The team project work will be supplemented with ...


Phil Like Playing?, José Ignacio Saavedra, Amanda &. Alanoud, Louise Gamble, Maureen Sledge Sep 2018

Phil Like Playing?, José Ignacio Saavedra, Amanda &. Alanoud, Louise Gamble, Maureen Sledge

Nexus Maximus

Through researching issues within central Philadelphia we decided we need to improve the health and overall well-being of the community members. In doing this we found that within the Center City, 56.3% of the population are made up of single adults, with the majority living alone.

They also have 65.8% of the population working in white collar jobs. These situations consist of long working hours which decrease the percentage in social interaction. This can also lead to other issues such as mental health, where stress levels are high.

Our solution to combat the problem is to create a ...


Estuary: Mobile Support Service, D'Vine Savage, Kerwin Dasque, Laina Posner, Nhan Dung, Lily Postus, Arynn Pratt, Ayana Curtis Sep 2018

Estuary: Mobile Support Service, D'Vine Savage, Kerwin Dasque, Laina Posner, Nhan Dung, Lily Postus, Arynn Pratt, Ayana Curtis

Nexus Maximus

Estuary: Mobile Support Service is a company that provides the Kensington community with the essentials to maintain and sustain overall health. We provide clean needles, food, water, clothing, and information/resources to help individuals with addiction, unemployment, housing etc. Our vision is to collaborate with several organizations within the Philadelphia area, such as Philabundance, and medical centers to provide the community with the best care.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be ...


Philly N' Me, Chi Hoo Hwang, Christopher Cherestal, Mackenzie Malcolm, Hannah Fitzpatrick, Michael Griffith Sep 2018

Philly N' Me, Chi Hoo Hwang, Christopher Cherestal, Mackenzie Malcolm, Hannah Fitzpatrick, Michael Griffith

Nexus Maximus

Our purpose was to increase the awareness of education opportunities, for the under-privileged youth in the city Philadelphia. To do this, we have created a program which uses our holistic approach, focusing on creating a well-rounded student.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend.

Teams will also explore opportunities to leverage that data in ...


Signs Of Trust, Samantha Barreto, Sylvie Abookire, Ronak Pansara, Wiebke Muehlhoff, Anthony Cho Sep 2018

Signs Of Trust, Samantha Barreto, Sylvie Abookire, Ronak Pansara, Wiebke Muehlhoff, Anthony Cho

Nexus Maximus

Signs of Trust is a service that provides the homeless with the choice of designing their own signs that is formatted to be trustworthy and honest. Passerby would be able to give to the homeless, by scanning the QR code on the signs, and selecting a gift card option that would given to the homeless by the service.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and ...


Neighborhood Socials In South Philadelphia, Cambria Graham, Khadijah Pearson, Tytisha Harris Sep 2018

Neighborhood Socials In South Philadelphia, Cambria Graham, Khadijah Pearson, Tytisha Harris

Nexus Maximus

Our project focuses on the lack of community in the South Philadelphia area and the high crime rates that are a result of this. We propose a monthly social event to be hosted at the parks and rec centers that are being revitalized by the state. We will start a sponsorship with Amazon who now owns Whole Foods as well as Aldi’s to promote healthy eating as well as provide food for the events.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific ...


Philagreen: "Buy Green. Give Green. Live Green", Irene Cooper, Will Bender, Victor Wright, Chelsea Nwanne, Vannessa Njoo Sep 2018

Philagreen: "Buy Green. Give Green. Live Green", Irene Cooper, Will Bender, Victor Wright, Chelsea Nwanne, Vannessa Njoo

Nexus Maximus

We will use green roofs to reduce levels of air pollution in Philadelphia, while simultaneously working to improve the lives of low-income Philadelphians through the donation of a green roof. Our program “Live One. Give One.” prices property owners based on yearly income

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend.

Teams will also explore ...


Integration Through Green Murals, Linh Duong, Kirsty Kelso, Julie Thiel, Alexis Cao Sep 2018

Integration Through Green Murals, Linh Duong, Kirsty Kelso, Julie Thiel, Alexis Cao

Nexus Maximus

Green Murals allow Asian residents to share culture and traditions through food and horticulture. Green Murals are Outdoor plant-based vertical gardens with themes such as vegetables, herbs with food/medicinal recipes, and flower arrangements reflecting traditional/historical stories. It increases green space in South Philadelphia, educate people to eat healthy, attract tourists to the areas, and improve social engagement.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship ...


Champ: Choosing Healthy Active Moving Play, Melanie Goldstein, Mica Lai, Omri Faroul, Valerie Leonard, Caroline Mccarthy, Suki Ghumman Sep 2018

Champ: Choosing Healthy Active Moving Play, Melanie Goldstein, Mica Lai, Omri Faroul, Valerie Leonard, Caroline Mccarthy, Suki Ghumman

Nexus Maximus

CHAMP is an afterschool program to get kids to become more active and healthy. The money raised will be used to fix the playground and make the area safer for children to play.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend.

Teams will also explore opportunities to leverage that data in meaningful ways that benefit ...


Infastructure Revitalizing Community, Kyle Hanson, Caitlin Hagan, Jessica Trio, Mariah Cadzow, Adie Tierney, Jihye Jang Sep 2018

Infastructure Revitalizing Community, Kyle Hanson, Caitlin Hagan, Jessica Trio, Mariah Cadzow, Adie Tierney, Jihye Jang

Nexus Maximus

Transforming an unused tunnel once used to hold a railroad into a package delivery system to deliver packages into Center City Philadelphia, the heart of the city, with minimal time waste and traffic blockage. Using foot and bike transportation to handle the "last mile issue". Lastly, in conjunction with the tunnel restructure,we are also proposing a city policy to limit large delivery trucks in center city during peak hours.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team ...


Track My Trip, Katie Taylor, Charlotte Calderwood, Anish Bachu, Chase Fike, Danielle Samson Sep 2018

Track My Trip, Katie Taylor, Charlotte Calderwood, Anish Bachu, Chase Fike, Danielle Samson

Nexus Maximus

We came up with a smart phone app to promote more physical activity which incorporates a reward scheme. This in turn helps to benefit local businesses.

Nexus Maximus V

The 2018 Challenge: "Improving Lives Through Healthy Communities" Teams will evaluate and seek innovation that supports the health and well-being of specific local community populations. The team’s project work will be supplemented with workshops on innovation, entrepreneurship, and content relevant to the theme, delivered by experts throughout the weekend.

Teams will also explore opportunities to leverage that data in meaningful ways that benefit and protect individuals and society. The team ...


Jefferson Digital Commons Quarterly Report: January-March 2018, Kelsey Duinkerken, Msi, James Copeland, Libt Apr 2018

Jefferson Digital Commons Quarterly Report: January-March 2018, Kelsey Duinkerken, Msi, James Copeland, Libt

Jefferson Digital Commons Reports

This quarterly report includes:

  • Articles
  • Conference materials
  • From the Archives - Yearbooks
  • Grand Rounds
  • Journals
  • MPH Capstones
  • Newsletters
  • Podcasts
  • Posters
  • Reports
  • Symposiums
  • What People are Saying About the Jefferson Digital Commons


Download Entire Issue: Gibbon Surgical Review, Volume 1, Issue 1, 2018 Mar 2018

Download Entire Issue: Gibbon Surgical Review, Volume 1, Issue 1, 2018

Gibbon Surgical Review

Download Entire Issue: Gibbon Surgical Review, Volume 1, Number 1, 2018


Silencing Of The Pink1 Gene Expression By Conditional Rnai Does Not Induce Dopaminergic Neuron Death In Mice., Hongxia Zhou, Björn H Falkenburger, Jörg B Schulz, Kim Tieu, Zuoshang Xu, Xu Gang Xia Feb 2018

Silencing Of The Pink1 Gene Expression By Conditional Rnai Does Not Induce Dopaminergic Neuron Death In Mice., Hongxia Zhou, Björn H Falkenburger, Jörg B Schulz, Kim Tieu, Zuoshang Xu, Xu Gang Xia

Kim Tieu

Transgenic RNAi, an alternative to the gene knockout approach, can induce hypomorphic phenotypes that resemble those of the gene knockout in mice. Conditional transgenic RNAi is an attractive choice of method for reverse genetics in vivo because it can achieve temporal and spatial silencing of targeted genes. Pol III promoters such as U6 are widely used to drive the expression of RNAi transgenes in animals. Tested in transgenic mice, a Cre-loxP inducible U6 promoter drove the broad expression of an shRNA against the Pink1 gene whose loss-of-functional mutations cause one form of familial Parkinson's disease. The expression of the ...


One Jefferson News February 2018, Performance Excellence Feb 2018

One Jefferson News February 2018, Performance Excellence

One Jefferson News

Over the past year, we have continued our One Jefferson journey and achieved a number of integration successes for the organization. In the attached, new issue of One Jefferson News, we celebrate strides being made by collaborative teams working on evolving the Physician Enterprise, Access, Supply Chain, and System Integration initiatives.

This issue includes:

  • Changing the Way We Drive Enhanced Performance
  • Collaborative Teams Accelerating Outcomes


A Word From The Writing Center (January 2018), Jennifer Wilson, Ms, Els Jan 2018

A Word From The Writing Center (January 2018), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

  • New Year, New Publishing Goals
  • Grammar Time
  • Writing Cafe


High-Resolution Physical Map For Chromosome 16q12.1-Q13, The Blau Syndrome Locus., Xiaoju Wang, Helena Kuivaniemi, Gina Bonavita, Charlene J Williams, Gerard Tromp Dec 2017

High-Resolution Physical Map For Chromosome 16q12.1-Q13, The Blau Syndrome Locus., Xiaoju Wang, Helena Kuivaniemi, Gina Bonavita, Charlene J Williams, Gerard Tromp

Charlene Williams

BACKGROUND: The Blau syndrome (MIM 186580), an autosomal dominant granulomatous disease, was previously mapped to chromosome 16p12-q21. However, inconsistent physical maps of the region and consequently an unknown order of microsatellite markers, hampered us from further refining the genetic locus for the Blau syndrome. To address this problem, we constructed our own high-resolution physical map for the Blau susceptibility region. RESULTS: We generated a high-resolution physical map that provides more than 90% coverage of a refined Blau susceptibility region. The map consists of four contigs of sequence tagged site-based bacterial artificial chromosomes with a total of 124 bacterial artificial chromosomes ...


Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi Dec 2017

Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

Use your break to expand your knowledge by checking out the many Grand Rounds posted in the Jefferson Digital Commons. Topics range from nasal reconstruction to sexuality and aging. With hours of Grand Rounds to experience (see some samples below), your holiday will transform from boredom to excitement! Happy holidays from the Jefferson Digital Commons!


A Word From The Writing Center (November 2017), Jennifer Wilson, Ms, Els Nov 2017

A Word From The Writing Center (November 2017), Jennifer Wilson, Ms, Els

A Word From the Writing Team (Newsletter)

This issue includes:

  • Stylish academic writing
  • The Write Stuff


Successes And Limitations Of Hepatitis C Screening In The Inpatient Setting: Initial Impact Of Pa Act Of 87 (Apha Roundtable Discussion), Madalene Zale, Mph Candidate, Ashley Park, Mph, Francis Nelson, Ms, Priya Mammen, Md, Mph Nov 2017

Successes And Limitations Of Hepatitis C Screening In The Inpatient Setting: Initial Impact Of Pa Act Of 87 (Apha Roundtable Discussion), Madalene Zale, Mph Candidate, Ashley Park, Mph, Francis Nelson, Ms, Priya Mammen, Md, Mph

College of Population Health Lectures, Presentations, Workshops

The Problem:

  • Estimated 3.2 million in US with chronic HCV; Baby Boomers 5 times more likely to be infected compared to other cohorts
  • Complex nature of HCV requires confirmation of HCV Ab screens to determine management and treatment needs.

Round table held at 2017 Annual APHA meeting in Atlanta, Georgia