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Full-Text Articles in Medicine and Health Sciences

Mental Health Among Collegiate Athletes, Stella Elise Fairbanks May 2024

Mental Health Among Collegiate Athletes, Stella Elise Fairbanks

Honors Thesis

Mental health has become increasingly more linked with athletics, especially collegiate athletics. There has been an increase in public acknowledgment of the presence of mental health in sports, specifically, more athletes are speaking about their mental health struggles as well as more research is being conducted in order to gain a greater understanding of the relationship between mental health and athletics. This literature review discusses athletes’ personal experiences of their mental health struggles, the presence of stigma associated with mental health and athletics, and the results of the recent NCAA, National Collegiate Athletic Association, research. This thesis aims to uncover …


Psychology Of Athletes: Impact Of Injuries On Mental Health, Caitlin Rainey May 2024

Psychology Of Athletes: Impact Of Injuries On Mental Health, Caitlin Rainey

Whittier Scholars Program

This article aims to contextualize the importance of understanding injuries in athletics and how those injuries impact mental health. With such a high prevalence of injuries in athletics, most studies analyze the physical implications on the athlete. It is vital that mental well being is studied as much as physical health throughout the injury and rehabilitation process. This study reviewed previous literature on the social impacts of team sports, psychological and social implications of injury, the impact of residual pain, and finally the process of retirement. A survey was also conducted at a small liberal arts college in Southern California …


Exploring The Lived Experience Of Self-Care In Young Adults With Type 2 Diabetes, Holly Berry-Price May 2024

Exploring The Lived Experience Of Self-Care In Young Adults With Type 2 Diabetes, Holly Berry-Price

Electronic Theses and Dissertations

Introduction

The prevalence of prediabetes in adults aged 18 or older was as high as 38% between 2017-2020. Youth-onset T2DM is a more aggressive phenotype than T2DM that occurs later in life. Young adults with T2DM have poorer health outcomes, lose an average of 15 years of life, all resulting in significant economic burden impacting the person. Current self-management interventions do not improve health outcomes in young adults with T2DM.

Purpose

The purpose of this research was to explore the self-care experiences of young adults living with T2DM.

Methods

Existential hermeneutic phenomenology informed the research. Inclusion criteria as follows: adults …


Examining The Effects Of Menstrual Cycle Phase And Hormonal Contraceptive Use On Women's Sleep, Charles Ethan Coombs May 2024

Examining The Effects Of Menstrual Cycle Phase And Hormonal Contraceptive Use On Women's Sleep, Charles Ethan Coombs

Psychological Science Undergraduate Honors Theses

Women overrepresent men for sub-optimal sleep, a consequence of hormone fluctuation in the menstrual cycle affecting sleep regulatory pathways. While research has examined the prevalence of sub-optimal sleep through cycle phases, little research has examined how hormonal contraceptives (HC’s) could similarly affect women’s sleep, while also neglecting to utilize subjective sleep measures. In this study, we examine subjective sleep quality among naturally cycling (NC) women, women using different HC types, and between active and inactive phase pill users by subjecting 463 women to a subjective sleep battery. We hypothesized that HC users would report more sub-optimal sleep than NC women. …


A Responsible Parrhesia? A Review Of The Price Of Secrecy, Sara Tafakori Apr 2024

A Responsible Parrhesia? A Review Of The Price Of Secrecy, Sara Tafakori

RadioDoc Review

The Price of Secrecy immerses the listener in stories of individual trauma, of child abuse and rape, yet also draws lessons from them of wider social significance. It includes moments of narrative catharsis, interspersed with repeated reminders that the stories are unfinished and open-ended—that the solutions lie out there, in social action, rather than in the stories themselves. The series also gestures towards structural critique, especially of ‘the legal constraints’ it identifies, yet it places greater importance on changing the wider culture through challenging the culture of secrecy and shame around victims’ stories of rape and abuse. This centrally means …


Promoting Child Rearing For Teen Mothers Within The Foster Care System, Monic Chavez, Rebecca King Apr 2024

Promoting Child Rearing For Teen Mothers Within The Foster Care System, Monic Chavez, Rebecca King

Spring 2024 Virtual OTD Capstone Symposium

Teenage pregnancy in foster care is twice the national average, with one-third becoming pregnant by 17. There are limited programs available to assist teen mothers in foster care in developing healthy parent-child relationships and parenting skills despite their desire to break the cycle of trauma and improve their relationships with their children. The objective of the capstone program is to establish and operate a residential maternity home-based trauma-informed parenting program that assists teenage mothers in foster care in developing parenting skills and a healthy parent-child relationship by providing them with the necessary resources and support.


Exploring The Experience Of Healthcare-Related Epistemic Injustice Among People With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, Joanne Hunt, Jessica Runacres, Daniel Herron, David Sheffield Apr 2024

Exploring The Experience Of Healthcare-Related Epistemic Injustice Among People With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome, Joanne Hunt, Jessica Runacres, Daniel Herron, David Sheffield

The Qualitative Report

Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) is a chronic, disabling yet clinically “contested” condition, previously theorised through a lens of epistemic injustice. Phenomena conceptually close to epistemic injustice, including stigma, are known to have deleterious consequences on a person’s health and life-world. Yet, no known primary studies have explored how people with ME/CFS experience healthcare through a lens of epistemic injustice, whilst a dearth of research explicitly exploring healthcare-related injustice from a patient perspective has been noted. This qualitative study seeks to address this gap. Semi-structured interviews and interpretative phenomenological analysis (IPA) were used to explore the experiences of …


Interdisciplinary Treatment Approach To Youth With Intellectual Or Developmental Disabilities And Co-Occurring Mental Health Conditions, Ashley Greenwald, Erika Ryst, Diane D. Thorkildson, Lauren Brown Apr 2024

Interdisciplinary Treatment Approach To Youth With Intellectual Or Developmental Disabilities And Co-Occurring Mental Health Conditions, Ashley Greenwald, Erika Ryst, Diane D. Thorkildson, Lauren Brown

Developmental Disabilities Network Journal

Many individuals with Intellectual and/or Developmental Disabilities (IDD) have co-occurring mental health needs, yet service delivery options often do not allow for the integrated delivery of mental health treatment and social behavioral support services. Siloed treatment approaches often result in lack of collaboration between providers, increasing the difficulty in accessing comprehensive and coordinated treatments and reducing treatment potential and effective outcomes. Additionally, many service providers in behavioral support services are not trained to address significant mental health needs; similarly, providers of mental health services lack experience in modifying practices for differing cognitive needs. The lack of cross-training and cross-collaboration makes …


Exploring The Occupation Of Education Of Children With Undocumented Immigrant Parents, Denise Perez, Susan Macdermott, Jazminne Orozco Arteaga Apr 2024

Exploring The Occupation Of Education Of Children With Undocumented Immigrant Parents, Denise Perez, Susan Macdermott, Jazminne Orozco Arteaga

Spring 2024 Virtual OTD Capstone Symposium

This research study highlights the detrimental effects of family separations on children's well-being, academic performance, and long-term outcomes. It emphasizes the urgent need for research on the mental health effects of immigration policies on children at risk of parental deportation. A qualitative research study was used to understand the experiences and challenges of adults with undocumented immigrant parents during various stages of schooling. The research utilizes the Kawa model to explore emotional factors and barriers affecting students' occupational engagement in an educational setting. The study aims to identify supports and barriers to school engagement for students with undocumented immigrant parents, …


Biopsychosocial Management Of Long Covid Fibromyalgia: Lessons From The Penn Medicine Lancaster General Health Fibromyalgia Program, Joseph Harrison, Dennis Given Psy.D. Apr 2024

Biopsychosocial Management Of Long Covid Fibromyalgia: Lessons From The Penn Medicine Lancaster General Health Fibromyalgia Program, Joseph Harrison, Dennis Given Psy.D.

The Journal of Integrated Primary Care

The COVID-19 pandemic has increased the prevalence of chronic health concerns worldwide, leading to a new population of patients suffering from Long Covid. Patients with Long Covid often experience persistent symptoms impacting multiple organ systems, including neuroimmune and neurological manifestations. Recently, attention has grown toward Long Covid patients developing chronic widespread pain similar to fibromyalgia. Fibromyalgia is a nociplastic pain disorder characterized by widespread pain and central sensitization with fatigue, sleep disturbances, and impairments in cognitive functioning. Given the nascent and limited research exploring new treatment options, patients need support now from biopsychosocial multi-modal pain management strategies. The Fibromyalgia Program …


An Exploration Of Self-Reported Training Needs For Anxiety Interventions Among Primary Care Behavioral Health Consultants, Katherine Buckheit, Ryan Willard, Kyle Possemato, Robyn Shepardson, Abigail Lashinsky, Jen Funderburk Apr 2024

An Exploration Of Self-Reported Training Needs For Anxiety Interventions Among Primary Care Behavioral Health Consultants, Katherine Buckheit, Ryan Willard, Kyle Possemato, Robyn Shepardson, Abigail Lashinsky, Jen Funderburk

The Journal of Integrated Primary Care

Introduction: Despite the need for greater training in evidence-based interventions for the treatment of anxiety in primary care behavioral health (PCBH), there are limited data on which interventions are desired by behavioral healthcare consultants (BHCs). The objective of this study was to identify which interventions BHCs desired more training in when treating anxiety in PCBH practice, and to examine if this preference was associated with theoretical orientation. Method: We conducted an online survey of PCBH providers regarding their training preferences for treatment of anxiety symptoms. The final sample comprised 291 BHCs recruited from e-mail listservs of national professional organizations. Providers …


Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk Apr 2024

Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk

SC Upstate Research Symposium

Purpose Statement: Several studies have shown that aerobic exercise can have a positive impact on alleviating symptoms experienced by individuals with Parkinson's disease (PD). Despite this evidence, the potential benefits of exercise for both PD patients and their care partners (PD dyad) remain unexplored. This research project investigates the effectiveness, therapeutic collaborations, and physical outcomes of a virtual reality (VR) tandem cycling program specifically designed for PD dyads.

Methods: Following approval from the Prisma Health Institutional Review Board, individuals with PD were identified and screened by clinical neurologists. The pre-testing measures for PD dyads (N=9) included emotional and cognitive status …


Childhood Cancer Survivorship: Navigating A New Normal In Middle Tennessee, Karli M. Beaumont Apr 2024

Childhood Cancer Survivorship: Navigating A New Normal In Middle Tennessee, Karli M. Beaumont

OTD Capstone Projects

Monroe Carell Jr. Children’s Hospital at Vanderbilt in partnership with Vanderbilt-Ingram Cancer Center offers REACH for Cancer Survivorship, a pediatric cancer survivorship clinic. REACH provides a full range of follow-up care designed to meet the physical, emotional, and practical needs of survivors and continuous surveillance of deleterious effects of cancer and its treatments. The purpose of this project was to meet population and agency needs through research of long- and late-term sequela while advocating for occupational therapy’s role in the oncology population through the proactive therapy and prospective surveillance models. The process of creating this project included synthesizing the literature, …


Multicultural Gerotranscendence: A Theoretical Approach To Working With Older Adults, Whitney George, Danielle Schlittler Apr 2024

Multicultural Gerotranscendence: A Theoretical Approach To Working With Older Adults, Whitney George, Danielle Schlittler

Adultspan Journal

With the growing number of the aging population, the call for counselors to understand the developmental processes of all clients is essential. The theories of gerotranscendence and multicultural counseling and therapy are central to the understanding of adult development in later life. The use of these two theories together provides a theoretical basis for counselors wishing to provide services to diverse older adults.


Mindfulness Through Biofeedback And Meditation Syllabus, Eric B. Miller Apr 2024

Mindfulness Through Biofeedback And Meditation Syllabus, Eric B. Miller

Open Educational Resources

No abstract provided.


Perceptions Of Dengue Risk And Acceptability Of A Dengue Vaccine In Residents Of Puerto Rico, Coral Rosado-Santiago, Carmen L. Pérez-Guerra, Nicole M. Vélez-Agosto, Claudia Colón-Burgos, Karla M. Marrero-Santos, Susanna K. Partridge, Amy E. Lockwood, Cathy Young, Steve H. Waterman, Gabriela Paz-Bailey Apr 2024

Perceptions Of Dengue Risk And Acceptability Of A Dengue Vaccine In Residents Of Puerto Rico, Coral Rosado-Santiago, Carmen L. Pérez-Guerra, Nicole M. Vélez-Agosto, Claudia Colón-Burgos, Karla M. Marrero-Santos, Susanna K. Partridge, Amy E. Lockwood, Cathy Young, Steve H. Waterman, Gabriela Paz-Bailey

Psychological Science Faculty Publications and Presentations

Dengvaxia is the first dengue vaccine recommended in the United States (U.S.). It is recommended for children aged 9–16 y with laboratory-confirmed previous dengue infection and living in areas where dengue is endemic. We conducted focus groups with parents and in-depth interviews with key informants (i.e. practicing pediatricians, physicians from immunization clinics, university researchers, and school officials) in Puerto Rico (P.R.) to examine acceptability, barriers, and motivators to vaccinate with Dengvaxia. We also carried out informal meetings and semi-structured interviews to evaluate key messages and educational materials with pediatricians and parents. Barriers to vaccination included lack of information, distrust toward …


Broken Promises: Prolonged Diminished Quality-Of-Life Among Liberian Ebola Survivors Half A Decade After The 2014-16 West African Outbreak, Jessi Hanson-Defusco, Decontee Davis, Meghana Bommareddy, Zainab Olaniyan Apr 2024

Broken Promises: Prolonged Diminished Quality-Of-Life Among Liberian Ebola Survivors Half A Decade After The 2014-16 West African Outbreak, Jessi Hanson-Defusco, Decontee Davis, Meghana Bommareddy, Zainab Olaniyan

Journal of Social, Behavioral, and Health Sciences

The 2014–2016 Ebola outbreak left thousands of Liberian survivors with severely diminished quality of life. Applying a social determinants framework, this mixed method study investigates to what extent Ebola virus disease (EVD) survivors suffer long-haul psychosocial stress, diminished quality-of-life factors, and the impact of EVD-related service provisions on their ongoing healing. We present the results of a quantitative analysis survey of data collected from 19 Liberian EVD survivors in 2022 using snowball sampling. Additionally, a qualitative analysis of survivor statements helps triangulate key statistical findings and inform causal mechanisms. Survivors report experiencing 5.25 of a total of 7 ongoing stressors …


A Manualized Occupational Therapy Communication Skills Intervention For Veterans With Posttraumatic Stress Disorder, Kiara Ainsworth, Steven M. Gerardi Apr 2024

A Manualized Occupational Therapy Communication Skills Intervention For Veterans With Posttraumatic Stress Disorder, Kiara Ainsworth, Steven M. Gerardi

Spring 2024 Virtual OTD Capstone Symposium

Post-traumatic stress disorder (PTSD) affects many individual's participation in daily activities. There is a lack of research in the area of occupational therapy (OT) treatment for veterans with PTSD. However, there has been an expressed need in the literature for a developed intervention for veterans with PTSD that includes communication skills as a component. To date, a manualized communication skills OT intervention for veterans with PTSD has not been created. The purpose of this paper was to develop a resource tool for occupational therapists to utilize as an intervention when treating veterans with PTSD using the framework of the Model …


From Cough To Crip: The Development Of Codeine From A Purely Medical Substance Into A Popular Recreational Drug, Rhett C. Vaughn Apr 2024

From Cough To Crip: The Development Of Codeine From A Purely Medical Substance Into A Popular Recreational Drug, Rhett C. Vaughn

Senior Theses

The research that was conducted aimed to elicit the influence that pop culture has on recreational drug consumption. Specifically, the usage of the drug codeine has become very popular in social media among many influencers. The research focuses on the prevalence of this drug across several media platforms, alongside the growing rate of consumption globally. Research was conducted primarily through combining various databases at various organizations and this study aims to compile the data into one coherent paper regarding codeine in pop culture. While, it cannot be solely attributed to one specific outlet or influence, this study found that alongside …


The Impact Of The Gut-Brain Axis On Alzheimer’S Disease, Elissa Wakim Mar 2024

The Impact Of The Gut-Brain Axis On Alzheimer’S Disease, Elissa Wakim

Best Integrated Writing

Elissa’s review for the Graduate Biomedical Review focuses on the links between the gastrointestinal tract and the brain; the gut-brain axis and the development of Alzheimer’s disease. As a student in the Microbiology and Immunology Masters Program Elissa was particularly interested in the gut microbiota and their connection to neurodegenerative disease. She tidily reviewed the literature and wrote a fascinating and compelling piece of work.


Best Integrated Writing 2024 - Complete Edition, Wright State University School Of Humanities And Cultural Studies Mar 2024

Best Integrated Writing 2024 - Complete Edition, Wright State University School Of Humanities And Cultural Studies

Best Integrated Writing

Best Integrated Writing includes excellent student writing from Integrated Writing courses taught at Wright State University. This is the first issue after a 5 year hiatus.


Development Of An Integrated Well-Being Scale For Japan, Kyoko Shimada, Masayuki Kiriu Mar 2024

Development Of An Integrated Well-Being Scale For Japan, Kyoko Shimada, Masayuki Kiriu

Japanese Society and Culture

Background: Although multiple scales related to well-being have been developed mainly in Western countries, it is important to consider Japanese cultural and historical elements when considering the concept of well-being in Japan. This study attempted to develop an integrated scale that considers Japanese cultural elements and characteristics.

Methods: As a preliminary survey, several Western made well-being scales were evaluated and 2 scales had factor structures that were generally as expected. Therefore, including these 2 scales, a total of 54 items (40 new items that represent characteristics that are important to Japanese) were added as integrated scales in the main analysis. …


Black Boys Om: A Case Study Of The Impacts Of Community And Culture On Wellness Practices, Khanh Pham Mar 2024

Black Boys Om: A Case Study Of The Impacts Of Community And Culture On Wellness Practices, Khanh Pham

Graduate Student and Postdoctoral Fellow Symposium

Black men continue to face health disparities due to systemic oppression. Research indicates that mind-body-spirit practices (MBSPs) can effectively improve mental and physical health, thereby reducing health disparities among Black men. However, MBSPs are often White-female-dominated practices, thus putting Black male practitioners at continued risks of under-representation and marginalization in MBSP spaces. The culturally specific nature of MBSP spaces may then be an important factor in MBSPs’ influence on Black men’s health. Therefore, we aimed to explore how culturally specific MBSP spaces impact Black male practitioners’ MBSPs. We collaborated with Black Boys OM (BBO), a global community of Black male …


Repetitive Negative Thinking As A Prospective Predictor Of Depression And Anxiety Symptoms In Autistic And Non-Autistic Incoming College Students, Erin Kckenney Mar 2024

Repetitive Negative Thinking As A Prospective Predictor Of Depression And Anxiety Symptoms In Autistic And Non-Autistic Incoming College Students, Erin Kckenney

Graduate Student and Postdoctoral Fellow Symposium

Background: Improving the understanding and treatment of mental health concerns, including depression and anxiety, are significant priorities for autistic adults (Benevides et al., 2020; Crane et al., 2019; Pellicano et al., 2014). While several theories have been proposed to explain the high prevalence of internalizing symptoms in autistic people, little longitudinal research has been done to investigate potential causal mechanisms. One potentially fruitful area of investigation is to explore how well-known contributors to depression/anxiety in the general population predict and/or moderate the development of internalizing symptoms in autistic individuals. Objectives: The current study investigates the relation of one established risk …


The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease, Noah Al-Hassan, Taha Al Hassan, Juan C. Lopez-Alvarenga, Maria Quinones, Seratna Guadarrama Mar 2024

The Role Of Oral Microbiota In Periodontitis And Alzheimer's Disease, Noah Al-Hassan, Taha Al Hassan, Juan C. Lopez-Alvarenga, Maria Quinones, Seratna Guadarrama

Research Symposium

Background: Periodontal disease (PD), affecting 20-50% of the global population is marked by biofilm-induced inflammation in oral tissues. Chronic PD results in systemic complications such as heart disease, stroke, and Alzheimer's. The red complex microbes, Porphyromonas gingivalis and Treponema denticola, play a pivotal role, penetrating the blood-brain barrier and contributing to neurodegeneration. Alzheimer's disease (AD), an irreversible neurodegenerative disorder, is linked to abnormal protein cleavage and potentially involves microbiologic components, including gram-positive cocci. Research suggests the presence of bacteria such as Porphyromonas, Actinomyces, and Treponema in autopsied AD brains. Investigating the microbiologic connection between PD and AD is crucial, considering …


[Discussions] Vol. 19 Iss. 1 Mar 2024

[Discussions] Vol. 19 Iss. 1

Discussions

This issue of Discussions was published for the Spring 2023 cycle.


Review Of The Safety And Efficacy Of Trauma-Focused Treatment Among Patients With Psychosis, Mary Eggers Mar 2024

Review Of The Safety And Efficacy Of Trauma-Focused Treatment Among Patients With Psychosis, Mary Eggers

Discussions

Among people who experience psychosis, many have comorbid post traumatic stress disorder (PTSD) that is frequently undiagnosed and untreated. Symptoms have long-term implications, such as hallucinations, posttraumatic intrusions, and an increased risk of physical health conditions, like heart disease and respiratory issues. Many clinicians believe that diagnosing and treating PTSD in this population will be dangerous, so these patients are often excluded from trauma-focused treatment based on their psychosis symptoms. This paper will review current data regarding the rates of undiagnosed PTSD among this population as well as the safety and efficacy of treatment options. PubMed was used to identify …


Investigating Interrater-Reliability In Assessing Social Behavior Of Monodelphis Domestica, Bianca A. Camacho, Johanna Perez, Jatziry L. Escobedo, John L. Vandeberg, Mario Gil Mar 2024

Investigating Interrater-Reliability In Assessing Social Behavior Of Monodelphis Domestica, Bianca A. Camacho, Johanna Perez, Jatziry L. Escobedo, John L. Vandeberg, Mario Gil

Research Symposium

Background: Reliable, consistent, and objective data is a goal all studies aim to achieve, but many struggle to obtain when subjective biases between researchers can occur. Inter-rater reliability (IRR) is a statistical measure used to quantify the degree of agreement between researchers qualitatively scoring the same phenomenon. The primary goal of this study is to enhance the methodology used to achieve optimal IRR. Using an established ethogram, our team of researchers scored the social behavior of the adult gray short-tailed opossum (Monodelphis domestica) to propose an effective method for achieving high IRR that can contribute to future …


Addressing Weight In Primary Care: Perspectives Of African American Young Adults With Serious Mental Illness, Sang Qin, Lindsay Sheehan, Janis Sayer, Kristin S. Williams, Julius Mercer, Ashley Scott, Tevin Anderson Mar 2024

Addressing Weight In Primary Care: Perspectives Of African American Young Adults With Serious Mental Illness, Sang Qin, Lindsay Sheehan, Janis Sayer, Kristin S. Williams, Julius Mercer, Ashley Scott, Tevin Anderson

Journal of Human Services Scholarship and Interprofessional Collaboration

Young adults with serious mental illness (SMI) experience disproportionate rates of physical illness. Morbidity and mortality are even worse for young African Americans with SMI, especially those who are overweight. Primary care physicians (PCPs) have an important role in addressing weight management. Current research explored these young patient’s perceptions of weight management and how PCPs can best address their weight concerns. Using community-based participatory research, we interviewed 25 African American aged 18-30 who were overweight and had a SMI. Results revealed 1) patient perceptions around weight and 2) patient preferences. Participants identified both positive and negative aspects of being overweight, …


Gamma-Aminobutyric Acid (Gaba) Neurons And Perineuronal Nets (Pnn) In The Monodelphis Domestica And Relevance To Psychiatric Disorders, Jatziry Z. Luna Escobedo, Mariela Garcia, John L. Vandeberg, Mario Gil Mar 2024

Gamma-Aminobutyric Acid (Gaba) Neurons And Perineuronal Nets (Pnn) In The Monodelphis Domestica And Relevance To Psychiatric Disorders, Jatziry Z. Luna Escobedo, Mariela Garcia, John L. Vandeberg, Mario Gil

Research Symposium

Background/ Purpose: Gamma-aminobutyric acid (GABA) is an amino acid that serves as the central nervous system’s (CNS) main inhibitory neurotransmitter. By inhibiting nerve transmission, it works to lower neuronal excitability. Altered GABA levels have been associated with a variety of psychiatric disorders, for example Epilepsies, Parkinson’s Disease, and Schizophrenia. Perineuronal nets (PNN) are extracellular molecules that are released by neurons and glial cells that modulate many neuronal and glial functions by encapsulating the inhibitory cells and neurites. Altered PNN levels serve as a potential trigger to synaptic imbalance. The purpose of this study is to quantify and analyze the presence, …