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1998

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Full-Text Articles in Medicine and Health Sciences

The Potential Of Collagenase As A New Therapy For Separation Of Human Retained Placenta: Hydrolytic Potency On Human, Equine And Bovine Placentae, Kellie Fecteau, Hugo Eiler Jun 2014

The Potential Of Collagenase As A New Therapy For Separation Of Human Retained Placenta: Hydrolytic Potency On Human, Equine And Bovine Placentae, Kellie Fecteau, Hugo Eiler

Kellie Fecteau

The purpose of this study was to determine to what degree bacterial collagenase may digest human placentae compared to equine and bovine placentae. Placenta samples from human, equine and bovine were incubated with bacterial collagenase solution at various concentrations. The degree of hydrolysis and collagen breakdown was measured by the release of total proteins and hydroxyproline into the incubation media. Also, whole placentae were injected via umbilical cord arteries with collagenase solution (200 U/ml, 200 ml total volume in human and 1000 ml in equine) and hydrolysis determined chemically and subjectively. Human and equine placental collagens were the most ...


Silicone Casting Of The Chambers Of The Heart And The Great Vessels, Robert Henry, Gregory Daniel, Robert Reed Jul 2012

Silicone Casting Of The Chambers Of The Heart And The Great Vessels, Robert Henry, Gregory Daniel, Robert Reed

Robert W Henry

No abstract provided.


Mental Health Parity: Implications For The State Of Florida, Bruce Levin, Ardis Hanson, Richard Coe, Ann Taylor Oct 2011

Mental Health Parity: Implications For The State Of Florida, Bruce Levin, Ardis Hanson, Richard Coe, Ann Taylor

Bruce Lubostsky Levin, DrPH, MPH

The federal Mental Health Parity Act of 1996 required insurers to offer the same benefits for mental disorders and substance abuse as they provide for physical disorders and includes parity for any annual or lifetime limitations and restrictions placed upon such coverage. To date, twenty-one states across the nation have enacted parity laws for mental health and/or substance abuse benefits. This paper summarizes the essential issues facing the state of Florida in the development of state mental health parity legislation, including an examination of the experiences of other states, a look at potential benefits, and a discussion of the ...


Radiographic, Densitometric, And Biomechanical Effects Of Recombinant Canine Somatotropin In An Unstable Ostectomy Gap Model Of Bone Healing In Dogs, Darryl Millis, Brent Wilkins, Gregory Daniel, Karl Hubner, Archie Mathews, Frances Buonomo, Kanaiyala Patell, Joseph Weigel Aug 2011

Radiographic, Densitometric, And Biomechanical Effects Of Recombinant Canine Somatotropin In An Unstable Ostectomy Gap Model Of Bone Healing In Dogs, Darryl Millis, Brent Wilkins, Gregory Daniel, Karl Hubner, Archie Mathews, Frances Buonomo, Kanaiyala Patell, Joseph Weigel

Joseph P. Weigel DVM

Objective—To determine the effect of recombinant canine somatotropin (STH) on radiographic, densitometric, and biomechanical aspects of bone healing using an unstable ostectomy gap model.

Study Design—After an ostectomy of the midshaft radius, bone healing was evaluated over an 8–week period in control dogs (n = 4) and dogs receiving recombinant canine STH (n = 4).

Animals or Sample Population—Eight sexually intact female Beagle dogs, 4 to 5 years old. Methods—Bone healing was evaluated by qualitative and quantitative evaluation of serial radiographs every 2 weeks. Terminal dual-energy x-ray absorptiometry and three-point bending biomechanical testing were also performed.

Results ...


Timp-1 Expression Is Increased In X-Linked Progressive Retinal Atrophy Despite Its Exclusion As A Candidate Gene, Caroline Zeiss, Gregory M. Acland, Gustavo D. Aguirre, Kunal Ray Dec 1998

Timp-1 Expression Is Increased In X-Linked Progressive Retinal Atrophy Despite Its Exclusion As A Candidate Gene, Caroline Zeiss, Gregory M. Acland, Gustavo D. Aguirre, Kunal Ray

Gustavo D. Aguirre, VMD, PhD

X-linked progressive retinal atrophy (XLPRA) is the only known natural animal model for X-linked retinitis pigmentosa (XLRP), a blinding disorder in man. The tissue inhibitor metalloproteinase 1 gene (TIMP-1), present in close proximity to one of the two XLRPloci, was tested as a candidate for XLPRA, by first characterizing the cDNA and gene from a normal dog. The cloned canine TIMP-1 cDNA is predicted to encode a protein of 207 amino acids with 66–83% identity in the deduced aa sequence with homologous mammalian genes. No sequence difference in the coding sequence of TIMP-1 was observed between normal and ...


Parent Influences On Adolescent Peer Orientation And Substance Use: The Interface Of Parenting Practices And Values, Karen Bogenschneider, Ming-Yeh Wu, Marcela Raffaelli, Jenner C. Tsay Dec 1998

Parent Influences On Adolescent Peer Orientation And Substance Use: The Interface Of Parenting Practices And Values, Karen Bogenschneider, Ming-Yeh Wu, Marcela Raffaelli, Jenner C. Tsay

Faculty Publications, Department of Psychology

This study examines how experiences in the family domain may magnify or mitigate experiences in the peer domain, and how processes in both milieus may influence adolescent substance use. The data derived from 666 European American mother-adolescent dyads and 510 European American father-adolescent dyads. Consistent with individuation-connectedness theory, mothers’ responsiveness lessened their adolescents’ orientation to peers, which, in turn, reduced adolescent substance use. This process was moderated by maternal values regarding adolescent alcohol use; that is, the relation of maternal responsiveness to adolescent substance use depended on the extent of maternal approval or disapproval of adolescent alcohol use. Among fathers ...


The Guillain-Barre Syndrome And The 1992-1993 And 1993-1994 Influenza Vaccines, Tamar Lasky, Gina J. Terracciano, Laurence Magder, Carol Lee Koski, Michael Ballesteros, Denis Nash, Shelley Clarke, Penina Haber, Paul D. Stolley, Lawrence B. Schonberger, Robert T. Chen Dec 1998

The Guillain-Barre Syndrome And The 1992-1993 And 1993-1994 Influenza Vaccines, Tamar Lasky, Gina J. Terracciano, Laurence Magder, Carol Lee Koski, Michael Ballesteros, Denis Nash, Shelley Clarke, Penina Haber, Paul D. Stolley, Lawrence B. Schonberger, Robert T. Chen

Publications and Research

Background
The number of reports of influenza-vaccine-associated Guillain-Barré syndrome to the national Vaccine Adverse Event Reporting System increased from 37 in 1992-1993 to 74 in 1993-1994, arousing concern about a possible increase in vaccine-associated risk.

Methods
Patients given a diagnosis of the Guillain-Barré syndrome in the 1992-1993 and 1993-1994 influenza-vaccination seasons were identified in the hospital-discharge data bases of four states. Vaccination histories were obtained by telephone interviews during 1995-1996 and were confirmed by the vaccine providers. Disease with an onset within six weeks after vaccination was defined as vaccine-associated. Vaccine coverage in the population was measured through a random-digit-dialing ...


Dynamics Of Human Immunodeficiency Virus Type 1 Replication In Vertically Infected Infants, Katherine Luzuriaga, Hulin Wu, Margaret M. Mcmanus, Paula Britto, William Borkowsky, Sandra K. Burchett, Betsy Smith, Lynne M. Mofenson, John L. Sullivan Dec 1998

Dynamics Of Human Immunodeficiency Virus Type 1 Replication In Vertically Infected Infants, Katherine Luzuriaga, Hulin Wu, Margaret M. Mcmanus, Paula Britto, William Borkowsky, Sandra K. Burchett, Betsy Smith, Lynne M. Mofenson, John L. Sullivan

Open Access Articles

Plasma human immunodeficiency virus type 1 (HIV-1) turnover and kinetics were studied in children aged 15 days to 2 years following the initiation of a triple antiretroviral drug regimen consisting of zidovudine, lamivudine, and nevirapine. HIV-1 turnover was at least as rapid as that previously described in adults; turnover rates were more rapid in infants and children aged 3 months to 2 years than in infants less than 3 months of age. These data confirm the central role of HIV-1 replication in the pathogenesis of vertical HIV-1 infection and reinforce the importance of early, potent combination therapies for the long-term ...


Release Of Camp Gating By The Alpha6beta4 Integrin Stimulates Lamellae Formation And The Chemotactic Migration Of Invasive Carcinoma Cells, Kathleen L. O'Connor, Leslie M. Shaw, Arthur M. Mercurio Dec 1998

Release Of Camp Gating By The Alpha6beta4 Integrin Stimulates Lamellae Formation And The Chemotactic Migration Of Invasive Carcinoma Cells, Kathleen L. O'Connor, Leslie M. Shaw, Arthur M. Mercurio

Cancer Biology Publications

The alpha6beta4 integrin promotes carcinoma in-vasion by its activation of a phosphoinositide 3-OH (PI3-K) signaling pathway (Shaw, L.M., I. Rabinovitz, H.H.-F. Wang, A. Toker, and A.M. Mercurio. Cell. 91: 949-960). We demonstrate here using MDA-MB-435 breast carcinoma cells that alpha6beta4 stimulates chemotactic migration, a key component of invasion, but that it has no influence on haptotaxis. Stimulation of chemotaxis by alpha6beta4 expression was observed in response to either lysophosphatidic acid (LPA) or fibroblast conditioned medium. Moreover, the LPA-dependent formation of lamellae in these cells is dependent upon alpha6beta4 expression. Both lamellae formation and chemotactic migration are ...


Analysis Of Murine Cd8(+) T-Cell Clones Specific For The Dengue Virus Ns3 Protein: Flavivirus Cross-Reactivity And Influence Of Infecting Serotype, Anne C. Spaulding, Ichiro Kurane, Francis A. Ennis, Alan L. Rothman Dec 1998

Analysis Of Murine Cd8(+) T-Cell Clones Specific For The Dengue Virus Ns3 Protein: Flavivirus Cross-Reactivity And Influence Of Infecting Serotype, Anne C. Spaulding, Ichiro Kurane, Francis A. Ennis, Alan L. Rothman

Open Access Articles

Serotype-cross-reactive dengue virus-specific cytotoxic T lymphocytes (CTL) induced during a primary dengue virus infection are thought to play a role in the immunopathogenesis of dengue hemorrhagic fever (DHF) during a secondary dengue virus infection. Although there is no animal model of DHF, we previously reported that murine dengue virus-specific CTL responses are qualitatively similar to human dengue virus-specific CTL responses. We used BALB/c mice to study the specificity of the CTL response to an immunodominant epitope on the dengue virus NS3 protein. We mapped the minimal H-2Kd-restricted CTL epitope to residues 298 to 306 of the dengue type 2 ...


In The Affirmative, Vol.5, [No.11] (Mid-December 1998/Mid-January 1999), Mick Martin, The Aids Project Dec 1998

In The Affirmative, Vol.5, [No.11] (Mid-December 1998/Mid-January 1999), Mick Martin, The Aids Project

In the Affirmative

No abstract provided.


D'Oh! An Analysis Of The Medical Care Provided To The Family Of Homer J. Simpson, Robert Patterson, Charles Weijer Dec 1998

D'Oh! An Analysis Of The Medical Care Provided To The Family Of Homer J. Simpson, Robert Patterson, Charles Weijer

Charles Weijer

No abstract provided.


Tractor Driver Killed In Overturn While Mowing, Kentucky Injury Prevention And Research Center Dec 1998

Tractor Driver Killed In Overturn While Mowing, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 44-year-old farm owner was killed when the tractor he was driving overturned. Using a rotary mower attached to a Ford 600 tractor, the farmer was mowing an area along the gravel road leading to his home in a very remote area of the county. On the east side was a fence and on the west a brush covered embankment. At the top of the seven-foot embankment was a sloping field that had been mowed earlier in the season. The tractor, having been purchased six weeks earlier, had undergone maintenance work but was not equipped with a Roll Over Protective ...


Parental Grief Responses To Perinatal Loss, Lisa M. Peacock Dec 1998

Parental Grief Responses To Perinatal Loss, Lisa M. Peacock

Masters Theses

An exploratory, descriptive design was used to examine parental grief and coping responses to perinatal loss. Florence Selder's Life Transition Theory (1989) was used as the conceptual fiamework. A survey approach was used for data collection. This included basic demographic questions, the Perinatal Bereavement Scale and the Jalowiec Coping Scale. A convenience sample was obtained, consisting of 24 women and 6 men in northern Michigan communities who had experienced a perinatal loss at some time in the past. Data were collected by an anonymous mailed survey. The results of the study revealed that all parents in this sample did ...


Sunday Times: Pig Blood May Replace Human Transfusions, Nick Newman, Cherry Norton Dec 1998

Sunday Times: Pig Blood May Replace Human Transfusions, Nick Newman, Cherry Norton

Vivian C. McAlister

Cartoon and news article regarding xenotransfusion research by Dr Vivian McAlister


How Pigs' Blood Could Save Lives: Canadian Study Could End Need For Human Donations, Allison Hanes, Randy Boswell Dec 1998

How Pigs' Blood Could Save Lives: Canadian Study Could End Need For Human Donations, Allison Hanes, Randy Boswell

Vivian C. McAlister

Dr. [Vivian McAlister] agrees that the risk of inter-species infection remains a key obstacle to producing safe pigblood products for people: "The most important thing is that the safety of this sort of thing has to be thoroughly assessed before any implementation. We're dealing more with the immunological barriers, not the infectious disease," he says of his research. "However, if the infectious risks were overcome, or they were understood, an animal source for blood donation" could revolutionize blood-supply services around the world, he says. Currently mired in a depressed pork market that is threatening to put many producers out ...


Tractor Operator Killed By Rotary Mower While Mowing Highway Right-Of-Way, Kentucky Injury Prevention And Research Center Dec 1998

Tractor Operator Killed By Rotary Mower While Mowing Highway Right-Of-Way, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Tractors/Logging

A 23-year-old male (the victim) was killed when he fell from the tractor he was operating and was run over by the attached rotary mower. The victim had been mowing near an interstate highway on-ramp at about 1:15 pm, when his right front tractor wheel hit a concrete drainage culvert, apparently jolting him off, into the path of the mower. Although he was working with a crew, none of his co-workers witnessed the event. A passing commercial truck driver saw the victim fall, pulled over, and called emergency medical services (EMS) on his cellular phone. EMS personnel arrived within ...


Factory Worker Entangled In Conveyor Belt Rollers, Kentucky Injury Prevention And Research Center Dec 1998

Factory Worker Entangled In Conveyor Belt Rollers, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Other

An 18-year-old male chop saw operator (the victim) died when his right arm became caught in the roller mechanism underneath a conveyor belt. He was pulled into the roller mechanism and suffered compressional asphyxia and blunt force injuries. The victim had left his usual work station for a break. When he did not return on time, his supervisor began to search for him. He saw the victim's legs hanging from the conveyor belt and immediately ran to him and shut off the power to the conveyor belt, radioing a guard to call for emergency medical services (EMS). He and ...


Factory Worker Caught In Overhead Conveyor While Hanging Transformers, Kentucky Injury Prevention And Research Center Dec 1998

Factory Worker Caught In Overhead Conveyor While Hanging Transformers, Kentucky Injury Prevention And Research Center

Fatality Case Reports--Other

A 29-year-old male factory worker (the victim) died after his head became caught at the point where an overhead chain conveyor made contact with an idler, or pinwheel, that allowed the conveyor to make a 90-degree turn. The conveyor was over seven feet above the floor, but the victim, who was 6'7" tall, was standing on a platform that enabled him to reach the hooks on the conveyor to hang transformer canisters for delivery to a paint booth. No one saw the victim get caught at the nip point, but his supervisor heard him call out and immediately pushed ...


Lower Lip Numbness Due To Peri-Radicular Dental Infection, Wei Cheong Ngeow Dec 1998

Lower Lip Numbness Due To Peri-Radicular Dental Infection, Wei Cheong Ngeow

Wei Cheong Ngeow

Lower lip numbness has always been a sinister symptom. Much has been written about it being the sole symptom of pathological lesions and metastatic tumours in the mandible. It may also be a symptom of manifestations of certain systemic disorders. A case of lower lip numbness resulting from the compression of the mental nerve by a peri-radicular abscess is presented because of the unusual nature of this spread of infection.


Tropicalizando A Medicina [Portuguese], Paulo A. Lotufo Dec 1998

Tropicalizando A Medicina [Portuguese], Paulo A. Lotufo

Paulo A Lotufo

No abstract provided.


Programs Of Assertive Community Treatment (Pact): A Critical Review, Tomi Gomory Dec 1998

Programs Of Assertive Community Treatment (Pact): A Critical Review, Tomi Gomory

Tomi Gomory

Advocates of Programs of Assertive Community Treatment (PACT) make numerous claims for this intensive intervention program, including reduced hospitalization, overall cost, and clinical symptomatology, and increased client satisfaction, and vocational and social functioning. However, a reanalysis of the controlled experimental research finds no empirical support for any of these claims. Instead, there is evidence that the program is both coercive and potentially harmful. The current promotion of PACT appears to be based more on professional enthusiasm for the medical model than upon any benefit to the clients.


Update - December 1998, Loma Linda University Center For Christian Bioethics Dec 1998

Update - December 1998, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- The Bible and Bioethics: Material, Method, and Metaphor


Marijuana Photonovel, A Year Up In Smoke, M. Susan Jones Dec 1998

Marijuana Photonovel, A Year Up In Smoke, M. Susan Jones

Nursing Faculty Publications

No abstract provided.


Yale Nurse: Yale School Of Nursing Newsletter, December, 1998, Yale University School Of Nursing Dec 1998

Yale Nurse: Yale School Of Nursing Newsletter, December, 1998, Yale University School Of Nursing

Yale School of Nursing Alumni Newsletters and Magazines

This issue features research at the School and the opening of an Office of Research and Policy.

Please contact the Yale Historical Medical Library if you need a higher resolution version.


Protecting The Fetus: The Criminalization Of Prenatal Drug Use, Kellam T. Parks Dec 1998

Protecting The Fetus: The Criminalization Of Prenatal Drug Use, Kellam T. Parks

William & Mary Journal of Race, Gender, and Social Justice

No abstract provided.


Detection Of Anionic Antimicrobial Peptides In Ovine Bronchoalveolar Lavage Fluid And Respiratory Epithelium, Kim A. Brogden, Mark R. Ackermann, Kenneth M. Huttner Dec 1998

Detection Of Anionic Antimicrobial Peptides In Ovine Bronchoalveolar Lavage Fluid And Respiratory Epithelium, Kim A. Brogden, Mark R. Ackermann, Kenneth M. Huttner

Veterinary Pathology Publications and Papers

Three small antimicrobial anionic peptides (AP) were originally isolated from an ovine pulmonary surfactant. However, their presence in bronchoalveolar lavage (BAL) fluid and tissues of the respiratory tract is unknown. In this study, we made affinity-purified rabbit polyclonal and mouse monoclonal antibodies to synthetic H-DDDDDDD-OH. Antibody specificity was assessed by a competitive enzyme-linked immunosorbent assay (ELISA), and the exact epitope binding sites were determined with analog peptides synthesized on derivatized cellulose. These antibodies were used to detect AP in BAL fluid by ELISA and in respiratory tissues by Western blot analysis and immunocytochemistry. BAL fluid from 25 sheep contained 0 ...


Cryptosporidium Parvum Initiates Inflammatory Bowel Disease In Germfree T Cell Receptor-Α-Deficient Mice, Randy E. Sacco, Joseph S. Haynes, James A. Harp, W. Ray Waters, Michael J. Wannemeuhler Dec 1998

Cryptosporidium Parvum Initiates Inflammatory Bowel Disease In Germfree T Cell Receptor-Α-Deficient Mice, Randy E. Sacco, Joseph S. Haynes, James A. Harp, W. Ray Waters, Michael J. Wannemeuhler

Veterinary Pathology Publications and Papers

Flora-bearing mice with targeted disruption of T cell receptor (TCR)-α or -β genes spontaneously develop intestinal inflammation with features similar to ulcerative colitis in humans. TCR-α-deficient mice maintained germfree or colonized with a limited number of intestinal bacteria failed to develop inflammatory bowel disease (IBD)-like lesions. Evidently, inflammation in these mice does not develop spontaneously or result from a generalized antigenic stimulation, but rather requires induction by a heretofore unidentified specific stimulus. We describe the development of IBD-like lesions in germfree TCR-α-deficient mice monoassociated with the protozoan Cryptosporidium parvum. Lesions were seen in distal ileum, cecum, and colon ...


"And The Band Played On...", David A. Nash Dec 1998

"And The Band Played On...", David A. Nash

Oral Health Science Faculty Publications

No abstract provided.


The Identification Of Domains And Competencies For Community Practice Occupational Therapy, Lisa Anne Werner Dec 1998

The Identification Of Domains And Competencies For Community Practice Occupational Therapy, Lisa Anne Werner

Master's Theses

Literature shows evidence of a shift in occupational therapy from traditional institutional settings to community-based settings. As increasing numbers of new and expert occupational therapists enter community-based practice, the need for competency identification for practice, education, and reimbursement becomes paramount. This qualitative research study sought to identify domains and competencies of community-based occupational therapy practice by interviewing three expert occupational therapists using the critical incident method in which each therapist described one therapeutic intervention with a client. This method, as seen in nursing studies (Benner, 1982, 1984), serves to elicit competencies embedded in expert practice. Thirty-nine competencies were described in ...