Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2009

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 1 - 30 of 5099

Full-Text Articles in Medicine and Health Sciences

Analyzing Direct Effects In Randomized Trials With Secondary Interventions: An Application To Hiv Prevention Trials, Michael Rosenblum, Nicholas Jewell, Mark Van Der Laan, Steven Shiboski, Ariane Van Der Straten, Nancy Padian Dec 2015

Analyzing Direct Effects In Randomized Trials With Secondary Interventions: An Application To Hiv Prevention Trials, Michael Rosenblum, Nicholas Jewell, Mark Van Der Laan, Steven Shiboski, Ariane Van Der Straten, Nancy Padian

Michael Rosenblum MD

The `Methods for improving reproductive health in Africa' trial is a recently completed randomized trial that investigated the effect of diaphragm and lubricant gel use in reducing infection by the human immunodeficiency virus (HIV) among susceptible women. 5045 women were randomly assigned to either the active treatment arm or not. Additionally, all subjects in both arms received intensive condom counselling and provision, the `gold standard' HIV prevention barrier method. There was much lower reported use of condoms in the intervention arm than in the control arm, making it difficult to answer important public health questions based solely on the intention-to-treat ...


The Risk Of Virologic Failure Decreases With Duration Of Hiv Suppression, At Greater Than 50% Adherence To Antiretroviral Therapy., Michael Rosenblum, Steven Deeks, Mark Van Der Laan, David Bangsberg Dec 2015

The Risk Of Virologic Failure Decreases With Duration Of Hiv Suppression, At Greater Than 50% Adherence To Antiretroviral Therapy., Michael Rosenblum, Steven Deeks, Mark Van Der Laan, David Bangsberg

Michael Rosenblum MD

Background We hypothesized that the percent adherence to antiretroviral therapy necessary to maintain HIV suppression would decrease with longer duration of viral suppression. Methodology Eligible participants were identified from the REACH cohort of marginally housed HIV infected adults in San Francisco. Adherence to antiretroviral therapy was measured through pill counts obtained at unannounced visits by research staff to each participant's usual place of residence. Marginal structural models and targeted maximum likelihood estimation methodologies were used to determine the effect of adherence to antiretroviral therapy on the probability of virologic failure during early and late viral suppression. Principal Findings A ...


Ivermectin Concentrations In Serum And Cerebrospinal Fluid After Intravenous Administration To Healthy Llamas, Sarel Van Amstel, A. Portmann, Tom Doherty, Shelley Newman, Jason Yarbrough, Sherry Cox Jan 2015

Ivermectin Concentrations In Serum And Cerebrospinal Fluid After Intravenous Administration To Healthy Llamas, Sarel Van Amstel, A. Portmann, Tom Doherty, Shelley Newman, Jason Yarbrough, Sherry Cox

Shelley Newman

The response to anthelmintic treatment in clinical cases of meningeal worm (Parelaphostrongylus tenuis) infestation remains unpredictable. In a previous study, ivermectin (IVM) was not detected in cerebrospinal fluid (C.S.F.) following subcutaneous administration to healthy llamas of IVM at 500μg/kg. In the present study, the same IVM dose was added to 1 L 0.9% NaCl and administered intravenously over 30 minutes to 6 healthy llamas. C.S.F and blood were collected, at baseline and 2, 4, 6, 12, 24, 48 and 60 hr after IVM administration. Serum and C.S.F. were stored at -400 ...


Ethics And Issues At The Sunset Of Life, Jane Gervasio, Dick Mcgowan, Priscilla Ryder Jan 2015

Ethics And Issues At The Sunset Of Life, Jane Gervasio, Dick Mcgowan, Priscilla Ryder

Priscilla T. Ryder

No abstract provided.


Effects Of Leuprolide Acetate On Selected Blood And Fecal Sex Hormones In Hispaniolan Amazon Parrots (Amazona Ventrais), Eric Klaphake, Kellie Fecteau, Martine Dewit, Cheryl Greenacre, Judith Grizzle, Michael Jones, Nancy Zagaya, L. Abney, Jack Oliver Jun 2014

Effects Of Leuprolide Acetate On Selected Blood And Fecal Sex Hormones In Hispaniolan Amazon Parrots (Amazona Ventrais), Eric Klaphake, Kellie Fecteau, Martine Dewit, Cheryl Greenacre, Judith Grizzle, Michael Jones, Nancy Zagaya, L. Abney, Jack Oliver

Kellie Fecteau

The luteinizing hormone-releasing hormone agonist leuprolide acetate is used commonly to anage reproductive problems in pet birds. To determine the effect of leuprolide acetate on plas a and fecal hormone levels in a psittacine species, a single 800 microg/kg dose of the 30-day depot form of leuprolide acetate was administered IM in 11 healthy, nonbreeding adult Hispaniolan Amazon parrots (Amazona ventralis), and plasma and fecal hormone levels were measured before and after leuprolide administration. At pooled baseline to 21 days postleuprolide acetate administration, sample collection day was significantly associated with plasma 17beta-estradiol and androstenedione levels and fecal 17beta-estradiol levels ...


Improving Information-Seeking Behaviors And Knowledge Base For Thesis Students In The Applied Behavior Analysis Graduate Program And Students In The Rehabilitation And Mental Health Counseling Graduate Program, Claudia Dold, Ardis Hanson Apr 2014

Improving Information-Seeking Behaviors And Knowledge Base For Thesis Students In The Applied Behavior Analysis Graduate Program And Students In The Rehabilitation And Mental Health Counseling Graduate Program, Claudia Dold, Ardis Hanson

Claudia J. Dold

We created a series of videocasts incorporating the use of library and networked technologies in the development of a thesis in applied behavior analysis. Not only does this project address departmental and college requirements regarding field of knowledge, it addresses Goal II of the USF Strategic Plan, i.e., “demonstrated acquisition of knowledge, communication and critical thinking skills; and competency to synthesize and apply new knowledge.” We used the "Taxonomy of information literacy competencies" model developed by Vitolo and Coulston (2002) as the pedagogocal framework for this project. By blending the six levels of the educational objectives of Bloom’s ...


Conjunctival Xanthoma In A Blue And Gold Macaw (Ara Ararauna). Souza M, Johnstone-Mclean N, Ward D, Newkirk K, Marcy Souza, Nancy Johnstone-Mcclean, Daniel Ward, Kim Newkirk Dec 2013

Conjunctival Xanthoma In A Blue And Gold Macaw (Ara Ararauna). Souza M, Johnstone-Mclean N, Ward D, Newkirk K, Marcy Souza, Nancy Johnstone-Mcclean, Daniel Ward, Kim Newkirk

Daniel A. Ward

No abstract provided.


Lysophosphatidylcholine Activates A Novel Pkd2-Mediated Signaling Pathway That Controls Monocyte Migration, M Tan, F Hao, Xuemin Xu, Gm Chisholm, Mei-Zhen Cui Jun 2013

Lysophosphatidylcholine Activates A Novel Pkd2-Mediated Signaling Pathway That Controls Monocyte Migration, M Tan, F Hao, Xuemin Xu, Gm Chisholm, Mei-Zhen Cui

Mei-Zhen Cui

OBJECTIVE: Monocyte activation and migration are crucial events in the development of atherosclerosis and other inflammatory diseases. This study examined the role of protein kinase D (PKD) in monocyte migration. Method and Results- PKD2 is the predominant isoform of PKD expressed in monocytic THP-1 cells and primary human monocytes. Lysophosphatidylcholine (lysoPC), a prominent component of oxidized low-density lipoprotein, induces rapid and marked PKD activation in these cells. Using multiple approaches, including dominant-negative mutants and small interfering RNA knock-down, we found that lysoPC-induced PKD2 activation was required for the activation of both ERK and p38 MAPK. p38 MAPK mediation of lysoPC-induced ...


Residues At P2-P1 Positions Of Epsilon- And Zeta-Cleavage Sites Are Important In Formation Of Beta-Amyloid Peptide, Jianxin Tan, Guozhang Mao, Mei-Zhen Cui, Bruce Lamb, Man-Sun Sy, Xuemin Xu Jun 2013

Residues At P2-P1 Positions Of Epsilon- And Zeta-Cleavage Sites Are Important In Formation Of Beta-Amyloid Peptide, Jianxin Tan, Guozhang Mao, Mei-Zhen Cui, Bruce Lamb, Man-Sun Sy, Xuemin Xu

Mei-Zhen Cui

Most of the Alzheimer's disease (AD)-linked mutations in amyloid precursor protein (APP), which cause abnormal production of beta-amyloid (Abeta), are localized at the major beta-secretase-and gamma-secretase cleavage sites. In this study, using an APP-knockout mouse neuronal cell line, our data demonstrated that at the P2-P1 positions of the epsilon-cleavage site at Abeta49 and the zeta-cleavage site at Abeta46, aromatic amino acids caused a strong reduction in total Abeta. On the other hand, residues with a long side chain caused a decrease in Abeta(40) and a concomitant increase in Abeta(42) and Abeta(38). These findings indicate that ...


The Gxxxg Motif In The Transmembrane Domain Of Abetapp Plays An Essential Role In The Interaction Of Ctf Beta With The Gamma-Secretase Complex And The Formation Of Amyloid-Beta, Guozhang Mao, Jianxin Tan, Mei-Zhen Cui, Dehua Chui, Xuemin Xu Jun 2013

The Gxxxg Motif In The Transmembrane Domain Of Abetapp Plays An Essential Role In The Interaction Of Ctf Beta With The Gamma-Secretase Complex And The Formation Of Amyloid-Beta, Guozhang Mao, Jianxin Tan, Mei-Zhen Cui, Dehua Chui, Xuemin Xu

Mei-Zhen Cui

Gamma-secretase-mediated processing of the amyloid-beta protein precursor (AbetaPP) is a crucial step in the formation of the amyloid-beta peptide (Abeta), but little is known about how the substrate AbetaPP interacts with the gamma-secretase complex. To understand the molecular events involved in gamma-secretase-mediated AbetaPP processing and Abeta formation, in the present study we determined the role of a well conserved GxxxG motif in the transmembrane domain of AbetaPP. Our data clearly demonstrate that substitution of aspartic acid for the key glycine residues in the GxxxG motif almost completely abolished the formation of Abeta. Furthermore, our data revealed that substitution of aspartic ...


Myelography Vs. Computed Tomography In The Evaluation Of Acute Thoracolumbar Intervertebral Disk Extrusion In Chondrodystrophic Dogs, Silke Hecht, William Thomas, Katia Marioni-Henry, R Echandi, Andrea Matthews, William Adams Feb 2013

Myelography Vs. Computed Tomography In The Evaluation Of Acute Thoracolumbar Intervertebral Disk Extrusion In Chondrodystrophic Dogs, Silke Hecht, William Thomas, Katia Marioni-Henry, R Echandi, Andrea Matthews, William Adams

William H Adams, DVM, DACVR

Myelography and/or computed tomography (CT) are commonly used to evaluate acute intervertebral disk extrusion in chondrodystrophic dogs. The purpose of this study was to evaluate the sensitivity of myelography and two different CT protocols in determining level and lateralization of acute thoracolumbar intervertebral disk extrusion in comparison with surgical findings, investigate interobserver variability, and determine examination duration times. Results of conventional CT, helical CT, and myelography were compared with surgical findings in 19 chondrodystrophic dogs with acute thoracolumbar intervertebral disk extrusion. Agreement among investigators was determined for different imaging modalities, and examination times were recorded. In the diagnosis of ...


What Is Your Diagnosis? Otitis In A Rabbit, Erica Stieve-Caldwell, Federica Morandi, Marcy Souza, William Adams Feb 2013

What Is Your Diagnosis? Otitis In A Rabbit, Erica Stieve-Caldwell, Federica Morandi, Marcy Souza, William Adams

William H Adams, DVM, DACVR

A 3-year-old sexually intact male Dutch rabbit was evaluated for nasal discharge and head tilt of 1 week's duration. The rabbit had been laterally recumbent for the 5 hours prior to admission. Upon physical examination, there was mucopurulent discharge from both nares and large amounts of desiccated and liquid caseous debris in the left ear. Results of a CBC revealed leukocytosis (18,100 cells/μL; reference range, 5,200 to 12,500 cells/μL); results of serum biochemical analysis were within reference ranges. The rabbit was anesthetized, and radiographs of the skull were obtained. Clinical signs were suggestive of ...


Use Of Interfering Rnas Targeted Against Feline Herpesvirus 1 Glycoprotein D For Inhibition Of Feline Herpesvirus 1 Infection Of Feline Kidney Cell, Rebecca Wilkes, Stephen Kania Oct 2012

Use Of Interfering Rnas Targeted Against Feline Herpesvirus 1 Glycoprotein D For Inhibition Of Feline Herpesvirus 1 Infection Of Feline Kidney Cell, Rebecca Wilkes, Stephen Kania

Rebecca P. Wilkes DVM, PhD, DACVM

Objective - To evaluate the use of RNA interference targeted against feline herpesvirus 1 (FHV-1) glycoprotein D for inhibition of FHV-1 infection of feline kidney cells. Sample Population - Crandell-Rees feline kidney cells. Procedures - Crandell-Rees feline kidney cells were transfected with small interfering RNAs (siRNAs) that were designed to inhibit expression of FHV-1 glycoprotein D. The effectiveness of the treatment was determined via measurement of amounts of glycoprotein D mRNA, intracellular glycoprotein D, and glycoprotein D expressed on the surface of infected cells and comparison with appropriate control sample data. Results - 2 of 6 siRNAs tested were highly effective in reducing expression ...


Development And Validation Of A Taqman Real-Time Reverse Transcription-Pcr For Rapid Detection Of Feline Calicivirus, M Abd-Eldaim, Rebecca Wilkes, K Thomas, Melissa Kennedy Oct 2012

Development And Validation Of A Taqman Real-Time Reverse Transcription-Pcr For Rapid Detection Of Feline Calicivirus, M Abd-Eldaim, Rebecca Wilkes, K Thomas, Melissa Kennedy

Rebecca P. Wilkes DVM, PhD, DACVM

Feline calicivirus (FCV) is a common cause of upper respiratory tract disease in cats and is associated with interstitial pneumonia, oral ulceration and polyarthritis. Recently, outbreaks have involved a highly virulent FCV that leads to multisystemic signs. Virus isolation and conventional RT-PCR are the most common methods used for FCV diagnosis. However, real-time RT-PCR offers a rapid, sensitive, specific and easy tool for nucleic acid detection. The objective of this study was to design a TaqMan probe-based, real-time RT-PCR assay for detection of FCV. It was determined in our previous study that the first 120 nucleotides of the 5' region ...


Health And Function Of Older Persons Volunteering For Habitat For Humanity, Janet Brown, Linda Mefford, Shu-Li Chen, Bonnie Callen, Allie Brown Aug 2012

Health And Function Of Older Persons Volunteering For Habitat For Humanity, Janet Brown, Linda Mefford, Shu-Li Chen, Bonnie Callen, Allie Brown

Allie J Brown

The purpose of this mixed method research study was to describe the health and functioning of a group of 40 older persons volunteering for Habitat for Humanity. We used qualitative interviews, participant observation, the updated version of the Short-Form-12 Health Survey (SF-12v2™), and health items on a questionnaire to explore health and functioning of older adult volunteers ages 57 to 88. The older participants were not physically healthier, but were mentally healthier than their community dwelling counterparts. Major health and functioning themes identified were: I'm still healthy; Adjusting to limitations; Everyone contributes; and Working hard. Participants discussed accommodations for ...


Health And Function Of Older Persons Volunteering For Habitat For Humanity, Janet Brown, Linda Mefford, Shu-Li Chen, Bonnie Callen, Allie Brown Aug 2012

Health And Function Of Older Persons Volunteering For Habitat For Humanity, Janet Brown, Linda Mefford, Shu-Li Chen, Bonnie Callen, Allie Brown

Allie J Brown

The purpose of this mixed method research study was to describe the health and functioning of a group of 40 older persons volunteering for Habitat for Humanity. We used qualitative interviews, participant observation, the updated version of the Short-Form-12 Health Survey (SF-12v2™), and health items on a questionnaire to explore health and functioning of older adult volunteers ages 57 to 88. The older participants were not physically healthier, but were mentally healthier than their community dwelling counterparts. Major health and functioning themes identified were: I’m still healthy; Adjusting to limitations; Everyone contributes; and Working hard. Participants discussed accommodations for ...


A Retrospective Study Of Eyelid Tumors From 43 Cats, Kim Newkirk, Barton Rohrbach Aug 2012

A Retrospective Study Of Eyelid Tumors From 43 Cats, Kim Newkirk, Barton Rohrbach

Kim M Newkirk

Submissions to the University of Tennessee pathology service from June 1999 to June 2008 were searched for feline cases of tumors involving the eyelids or nictitans. Forty-three tumors were identified. The average age at diagnosis was 10.4 years. Significantly more males than females had eyelid tumors. There were 12 squamous cell carcinomas (SCCs), 11 mast cell tumors (MCTs), 6 hemangiosarcomas (HSAs), 4 adenocarcinomas (ACAs), 3 peripheral nerve sheath tumors (PNSTs), 3 lymphomas, 3 apocrine hidrocystomas (AHCs), and 2 hemangiomas. Cats with MCTs were significantly younger than cats with all other tumor types combined. In contrast, cats with SCCs were ...


Empowering Patient Safety Outreach Through Interprofessional Partnerships: Educating Our Communities, Chris Childs, A. Faltinek, L. Heinz, Linda Walton, L. Zipperer Jul 2012

Empowering Patient Safety Outreach Through Interprofessional Partnerships: Educating Our Communities, Chris Childs, A. Faltinek, L. Heinz, Linda Walton, L. Zipperer

Linda J. Walton

No abstract provided.


Macroscopic Anatomy Of The Great Vessels Of The Ringed Seal (Phoca Hispida), H Smodlaka, Robert Henry, Robert Reed Jul 2012

Macroscopic Anatomy Of The Great Vessels Of The Ringed Seal (Phoca Hispida), H Smodlaka, Robert Henry, Robert Reed

Robert B. Reed, Jr., DVM, Ph.D.

The ringed seal [Pusa (Phoca) hispida], as well as other seals, exhibits unique anatomical properties when compared to its terrestrial counterparts. In the ringed seal, the most conspicuous marine adaptation is the aortic bulb. This large dilatation of the ascending aorta is comparable to that found in other seal species and marine mammals. The branches of the ascending aorta (brachiocephalic trunk, left common carotid artery and left subclavian artery) are similar to those of higher primates and man. The peculiarities of the venous system are: three pulmonary veins, a pericardial venous plexus, a caval sphincter, a hepatic sinus with paired ...


Macroscopic Anatomy Of The Ringed Seal (Phoca Hispida) Lower Respiratory System., H Smodlaka, Robert Henry, Robert Reed Jul 2012

Macroscopic Anatomy Of The Ringed Seal (Phoca Hispida) Lower Respiratory System., H Smodlaka, Robert Henry, Robert Reed

Robert B. Reed, Jr., DVM, Ph.D.

This investigation serves to document the normal anatomical features of the lower respiratory tract of the ringed seal [ Pusa ( phoca) hispida]. Evaluation of embalmed specimens and tracheobronchial casts showed that the right lung of this seal consists of four lobes while the left has only three lobes. The ventral margins of the lungs do not reach the sternum causing them to form the boundary of the broad recessus costomediastinalis. Lung lobation corresponds with bronchial tree division. Pulmonary venous drainage includes right and left common veins draining ipsilateral cranial and middle lung lobes, and one common caudal vein draining both caudal ...


Use Of Dashboard To Monitor Educational Program, Nancy Howell, India Lane, Craige Thomas, Anik Vasington Apr 2012

Use Of Dashboard To Monitor Educational Program, Nancy Howell, India Lane, Craige Thomas, Anik Vasington

India F. Lane

No abstract provided.


Acute Postrenal Azotemia: Etiology, Clinicopathology, And Pathophysiology, J Fischer, India Lane, Jennifer Stokes Apr 2012

Acute Postrenal Azotemia: Etiology, Clinicopathology, And Pathophysiology, J Fischer, India Lane, Jennifer Stokes

India F. Lane

When rupture or obstruction of the urinary tract prevents the normal collection and expulsion of urine from the body, the resulting azotemia is termed postrenal. Postrenal azotemia can coexist with prerenal and/or renal azotemia. Detection of postrenal azotemia requires attentiveness to the history and physical examination findings and to the results of specifically directed diagnostic tests. Prompt correction of postrenal causes of azotemia limits the potential for intrinsic renal damage and can contribute to a positive clinical outcome; therefore, postrenal azotemia should be investigated in all azotemic patients.


The Role Of Key Adipokines In Obesity And Insulin Resistance In Cats, Angela Lusby, Claudia Kirk, Joe Bartges Jan 2012

The Role Of Key Adipokines In Obesity And Insulin Resistance In Cats, Angela Lusby, Claudia Kirk, Joe Bartges

Angela L Witzel (Lusby) DVM, PhD, DACVN

No abstract provided.


Lc Determination Of Tramadol, M1, M2, M4, And M5 In Plasma, Jason Yarbrough, Cheryl Greenacre, Marcy Souza, Sherry Cox Jan 2012

Lc Determination Of Tramadol, M1, M2, M4, And M5 In Plasma, Jason Yarbrough, Cheryl Greenacre, Marcy Souza, Sherry Cox

Cheryl B Greenacre DVM

A new LC procedure for the determination of tramadol, an analgesic, and its metabolites has been developed and validated. Following a liquid–liquid extraction using ethyl acetate and hexane, samples were separated by RP-LC on a Symmetry C18 column and quantified using fluorescence detection at an excitation of 202 nm and an emission of 296 nm. The mobile phase was a mixture of potassium dihydrogen phosphate buffer (0.01 M), 0.1% triethylamine (pH 2.9) and acetonitrile, with a flow-rate of 1.1 mL min−1. The standard curve ranged from 5 to 5,000 ng mL−1. Intra-and ...


Effect Of Intravenous Administration Of Tramadol Hydrochloride On The Minimum Alveolar Concentration Of Isoflurane In Rabbits, Christine Egger, Marcy Souza, Cheryl Greenacre, Sherry Cox, Barton Rohrbach Jan 2012

Effect Of Intravenous Administration Of Tramadol Hydrochloride On The Minimum Alveolar Concentration Of Isoflurane In Rabbits, Christine Egger, Marcy Souza, Cheryl Greenacre, Sherry Cox, Barton Rohrbach

Cheryl B Greenacre DVM

OBJECTIVE: To evaluate the effect of IV administration of tramadol hydrochloride on the minimum alveolar concentration of isoflurane (ISOMAC) that prevented purposeful movement of rabbits in response to a noxious stimulus. ANIMALS: Six 6- to 12-month-old female New Zealand White rabbits. PROCEDURES: Anesthesia was induced and maintained with isoflurane in oxygen. A baseline ISOMAC was determined by clamping a pedal digit with sponge forceps until gross purposeful movement was detected or a period of 60 seconds elapsed. Subsequently, tramadol (4.4 mg/kg) was administered IV and the posttreatment ISOMAC (ISOMAC(T)) was measured. RESULTS: Mean +/- SD ISOMAC and ISOMAC ...


Effects Of Leuprolide Acetate On Selected Blood And Fecal Sex Hormones In Hispaniolan Amazon Parrots (Amazona Ventrais), Eric Klaphake, Kellie Fecteau, Martine Dewit, Cheryl Greenacre, Judith Grizzle, Michael Jones, Nancy Zagaya, L. Abney, Jack Oliver Jan 2012

Effects Of Leuprolide Acetate On Selected Blood And Fecal Sex Hormones In Hispaniolan Amazon Parrots (Amazona Ventrais), Eric Klaphake, Kellie Fecteau, Martine Dewit, Cheryl Greenacre, Judith Grizzle, Michael Jones, Nancy Zagaya, L. Abney, Jack Oliver

Cheryl B Greenacre DVM

The luteinizing hormone-releasing hormone agonist leuprolide acetate is used commonly to anage reproductive problems in pet birds. To determine the effect of leuprolide acetate on plas a and fecal hormone levels in a psittacine species, a single 800 microg/kg dose of the 30-day depot form of leuprolide acetate was administered IM in 11 healthy, nonbreeding adult Hispaniolan Amazon parrots (Amazona ventralis), and plasma and fecal hormone levels were measured before and after leuprolide administration. At pooled baseline to 21 days postleuprolide acetate administration, sample collection day was significantly associated with plasma 17beta-estradiol and androstenedione levels and fecal 17beta-estradiol levels ...


Comparison Of A Human Portable Blood Glucose Meter, Veterinary Portable Blood Glucose Meter, And Automated Chemistry Analyzer For Measurement Of Blood Glucose Concentrations In Dogs, Beth Johnson, Michael Fry, Bente Flatland, Claudia Kirk Jan 2012

Comparison Of A Human Portable Blood Glucose Meter, Veterinary Portable Blood Glucose Meter, And Automated Chemistry Analyzer For Measurement Of Blood Glucose Concentrations In Dogs, Beth Johnson, Michael Fry, Bente Flatland, Claudia Kirk

Bente Flatland

OBJECTIVE: To compare blood glucose concentrations measured with 2 portable blood glucose meters (PBGMs) validated for use in dogs (PBGM-D) and humans (PBGM-H) and an automated chemistry analyzer. DESIGN: Validation study. SAMPLE POPULATION: 92 samples of fresh whole blood and plasma from 83 dogs with various diseases. PROCEDURES: Each PBGM was used to measure whole blood glucose concentration, and the automated analyzer was used to measure plasma glucose concentration. Passing-Bablok linear regression and Bland-Altman plots were used to determine correlations and bias between the PBGMs and the automated analyzer. Calculated acceptability limits based on combined inherent instrument imprecision were used ...


Feline Gastrointestinal Eosinophilic Sclerosing Fibroplasia, Linden Craig, E Hardam, D Hertzke, Bente Flatland, Barton Rohrbach, R Moore Jan 2012

Feline Gastrointestinal Eosinophilic Sclerosing Fibroplasia, Linden Craig, E Hardam, D Hertzke, Bente Flatland, Barton Rohrbach, R Moore

Bente Flatland

A retrospective study of cases of a unique intramural inflammatory mass within the feline gastrointestinal tract was performed in order to describe and characterize the lesion. Twenty-five cases were identified from archival surgical and postmortem tissues. The lesion most often occurred as an ulcerated intramural mass at the pyloric sphincter (n=12) or the ileocecocolic junction or colon (n=9); the remaining cases were in the small intestine. Seven cases also had lymph node involvement. The lesions were characterized by eosinophilic inflammation, large reactive fibroblasts, and trabeculae of dense collagen. Intralesional bacteria were identified in 56% of the cases overall ...


The Epidemiology Of Lion Lentivirus Among A Population Of Free-Ranging Lions (Panthera Leo) In Kruger National Park, Republic Of South Africa, H Adams, Melissa Kennedy, M Vuuren, A Bosman, D Keet, John New Jan 2012

The Epidemiology Of Lion Lentivirus Among A Population Of Free-Ranging Lions (Panthera Leo) In Kruger National Park, Republic Of South Africa, H Adams, Melissa Kennedy, M Vuuren, A Bosman, D Keet, John New

Melissa A. Kennedy

Feline immunodeficiency virus is a lentivirus of domestic cats that causes significant lifelong infection. Infection with this or similar lentiviruses has been detected in several nondomestic feline species, including African lions (Panthera leo). Although lion lentivirus (FIVple) infection is endemic in certain lion populations in eastern and southern Africa, little is known about its pathogenic effects or its epidemiological impact in free-ranging lions. This report describes the epidemiological investigation of lentivirus positivity of free-ranging lions in the Kruger National Park, South Africa. A nested polymerase chain reaction assay for virus detection was performed on all whole blood samples collected. In ...


What Is Your Diagnosis? Traumatic Diaphragmatic Hernia In A Dog, A Little, Silke Hecht, Claudia Kirk, Mark Bohling Dec 2011

What Is Your Diagnosis? Traumatic Diaphragmatic Hernia In A Dog, A Little, Silke Hecht, Claudia Kirk, Mark Bohling

Claudia A Kirk

No abstract provided.