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2000

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Articles 1 - 30 of 1167

Full-Text Articles in Medicine and Health Sciences

Diffuse Annular Fusiform Adenocarcinoma In A Dog., Bente Flatland, M Praeter, Shelley Newman, D Sponenberg, J Chao Jan 2015

Diffuse Annular Fusiform Adenocarcinoma In A Dog., Bente Flatland, M Praeter, Shelley Newman, D Sponenberg, J Chao

Shelley Newman

Canine colonic intestinal adenocarcinoma typically presents as rectal polypoid or annular stenotic masses causing clinical signs consistent with large bowel disease. This report discusses an unusual case of intestinal adenocarcinoma in an 11-year-old, neutered male German shepherd dog presented for evaluation of anorexia, profuse watery diarrhea, and weight loss. In this dog, colonic adenocarcinoma diffusely infiltrated the entire large bowel and caused an annular fusiform lesion, as confirmed by endoscopic biopsies and postmortem examination. Other unique features included a paucity of desmoplasia associated with the neoplastic lesion and widespread metastasis to regional lymph nodes, lung, and prostate.


Detection Of A Novel Quiescence-Dependent Protein Kinase, Hwa-Chain Wang, Kellie Fecteau Jun 2014

Detection Of A Novel Quiescence-Dependent Protein Kinase, Hwa-Chain Wang, Kellie Fecteau

Kellie Fecteau

We have identified a cell quiescence-specific 33-kDa cytoplasmic protein kinase (p33(QIK), Quiescence-Induced Kinase) based on induction of p33(QIK)-specific kinase activity of cells growth-arrested in the quiescent phase and deactivation upon entry into the cell cycle. Blockage of macromolecular synthesis prevents p33(QIK) from deactivation, indicating a requirement of newly synthesized regulators for deactivation of p33(QIK) during G(0)/G(1) transition. Stress shock induces additional increases of p33(QIK) activity in a quiescence-dependent manner that correlates with induction of apoptosis. Using a specific antibody to Krs1/Mst2 protein, we found that p33(QIK) is related to ...


New Dimensions Of Economic Well-Being Among People With Mental Illness: Evidence From Healthcare For Communities, Carole Gresenz, Roland Sturm Jan 2013

New Dimensions Of Economic Well-Being Among People With Mental Illness: Evidence From Healthcare For Communities, Carole Gresenz, Roland Sturm

Roland Sturm

No abstract provided.


Borrelia Burgdorferi Infection In A Red Wolf (Canis Rufus), Rebecca Penrose, Edward Ramsay, John New, Stephen Kania Oct 2012

Borrelia Burgdorferi Infection In A Red Wolf (Canis Rufus), Rebecca Penrose, Edward Ramsay, John New, Stephen Kania

Rebecca P. Wilkes DVM, PhD, DACVM

No abstract provided.


Borrelia Burgdorferi Infection In A Red Wolf (Canis Rufus), Rebecca Penrose, Edward Ramsay, John New, Stephen Kania Aug 2012

Borrelia Burgdorferi Infection In A Red Wolf (Canis Rufus), Rebecca Penrose, Edward Ramsay, John New, Stephen Kania

Stephen A Kania

No abstract provided.


Vertical Integration Of Pbl In A New Veterinary Curriculum, Nancy Howell, R. Shull, India Lane Apr 2012

Vertical Integration Of Pbl In A New Veterinary Curriculum, Nancy Howell, R. Shull, India Lane

India F. Lane

No abstract provided.


Development Of An Enzyme Linked Immunosorbent Assay (Elisa) For The Diagnosis Of Ophidian Paramyxovirus (Opv), Stephen Kania, Melissa Kennedy, N Nowlin, V Diderrich, Edward Ramsay Mar 2012

Development Of An Enzyme Linked Immunosorbent Assay (Elisa) For The Diagnosis Of Ophidian Paramyxovirus (Opv), Stephen Kania, Melissa Kennedy, N Nowlin, V Diderrich, Edward Ramsay

Stephen A Kania

No abstract provided.


Cardiopulmonary And Anesthetic Effects Of Medetomidine-Ketamine-Butorphanol And Antagonism With Atipamezole In Servals (Felis Serval), Jennifer Langan, Juergen Schumacher, Christal Pollock, Susan Orosz, Michael Jones, Ralph Harvey Nov 2011

Cardiopulmonary And Anesthetic Effects Of Medetomidine-Ketamine-Butorphanol And Antagonism With Atipamezole In Servals (Felis Serval), Jennifer Langan, Juergen Schumacher, Christal Pollock, Susan Orosz, Michael Jones, Ralph Harvey

Juergen P. Schumacher

Seven (three male and four female) 4-7-yr old captive servals (Felis serval) weighing 13.7 +/- 2.3 kg were used to evaluate the cardiopulmonary and anesthetic effects of combined intramuscular injections of medetomidine (47.4 +/- 10.3 microg/kg), ketamine (1.0 +/- 0.2 mg/kg), and butorphanol (0.2 +/- 0.03 mg/kg). Inductions were smooth and rapid (11.7 +/- 4.3 min) and resulted in good muscle relaxation. Significant decreases in heart rate (85 +/- 12 beats/min) at 10 min after injection and respiratory rate (27 +/- 10 breaths/min) at 5 min after injection continued throughout the immobilization ...


Pharmacokinetics Of Amoxicillin Plus Clavulanic Acid In Blue-Fronted Amazon Parrots (Amazona Aestiva Aestiva), Susan Orosz, Michael Jones, Sherry Cox, Nancy Zagaya, Donita Frazier Sep 2011

Pharmacokinetics Of Amoxicillin Plus Clavulanic Acid In Blue-Fronted Amazon Parrots (Amazona Aestiva Aestiva), Susan Orosz, Michael Jones, Sherry Cox, Nancy Zagaya, Donita Frazier

Sherry Cox

In the face of increasing bacterial drug resistance because of β-lactamase production, many microbial infections can be treated effectively by combining clavulanic acid with amoxicillin. Judicious drug use that includes defining the optimum dosage is important to control development of resistance to this drug combination. In this study, amoxicillin and clavulanic acid were administered to blue-fronted Amazon parrots (Amazona aestiva aestiva) in a multiple dosing trial. Birds were gavaged with 125 mg/kg of the drug combination at 0800, 1600, and 2200 hours on days 15. The half-lives of amoxicillin and clavulanic acid were similar to those in humans; however ...


Cardiopulmonary Effects Of Sevoflurane In Garnett’S Greater Bush Baby (Otolemur Garnettii), George Langan, Ralph Harvey, Dorcas O'Rourke, M. Fontenot, Juergen Schumacher Aug 2011

Cardiopulmonary Effects Of Sevoflurane In Garnett’S Greater Bush Baby (Otolemur Garnettii), George Langan, Ralph Harvey, Dorcas O'Rourke, M. Fontenot, Juergen Schumacher

Juergen P. Schumacher

Purpose: A study was conducted to assess the cardiopulmonary and anesthetic effects of sevoflurane anesthesia on Garnett’s Greater Bush Baby (Otolemur garnettii). Methods: Anesthesia was induced in ten animals with 8% sevoflurane and was maintained by use of 2.5% sevoflurane for 30 minutes. Induction and recovery times were recorded. Heart and respiratory rates (RR), end-tidal carbon dioxide concentration (ET CO2), arterial blood pressures, relative arterial blood oxygen saturation (SpO2), arterial partial pressure of oxygen (PaO2), arterial partial pressure of carbon dioxide (PaCO2), and pH were monitored. Preand poststudy CBC and serum biochemical values were compared. Results: Anesthesia induction ...


Tissue Strength And Wound Morphology Of The Equine Linea Alba After Ventral Median Celiotomy, P Chism, F Latimer, C Patton, Barton Rohrbach, James Blackford Jul 2011

Tissue Strength And Wound Morphology Of The Equine Linea Alba After Ventral Median Celiotomy, P Chism, F Latimer, C Patton, Barton Rohrbach, James Blackford

James T. Blackford DVM, MS, DACVS

The tensile strength and wound morphology of the equine linea alba was assessed at intervals over 6 months after ventral median caeliotomy in 18 adult horses (400-500 kg). Linea alba tensile strength and wound morphology were measured at 2, 4, 8, 16, and 24 weeks postoperatively. Linea alba samples from 3 unoperated horses were used as controls. Tensile strength and thickness of incised linea alba samples collected at 2, 4, 8, 16, and 24 weeks after ventral median caeliotomy were compared with control linea alba samples. Additional samples were subjectively assessed for wound morphology, notably collagen morphology. Control linea alba ...


Studies Of Brain Activity Correlates Of Behavior In Individuals With And Without Developmental Disabilities, Amanda Difiore, William V. Dube, Stephen Oross Iii, Krista M. Wilkinson, Curtis K. Deutsch, William J. Mcilvane Dec 2000

Studies Of Brain Activity Correlates Of Behavior In Individuals With And Without Developmental Disabilities, Amanda Difiore, William V. Dube, Stephen Oross Iii, Krista M. Wilkinson, Curtis K. Deutsch, William J. Mcilvane

Eunice Kennedy Shriver Center Publications

There is a rich assortment of brain imaging methodologies that permits evaluation of the covert events that are necessary to complete a comprehensive account of behavior. Among the latter methodologies, our laboratories have begun to explore event-related potential (ERP) research to complement traditional behavior analysis.


Effects Of Cold Stress On Worker Performance In A Refrigerated Warehouse, Margarita Chernyshov Dec 2000

Effects Of Cold Stress On Worker Performance In A Refrigerated Warehouse, Margarita Chernyshov

Theses

The effects of cold stress were evaluated on worker performance in a low temperature environment. Level of clothing protection was compared to the functional ability of working on various tasks. Physical as well as mental effects were discussed to develop a basis for the physiological adaptations due to cold stress. The study focused on workers that performed various simple and complex tasks in a refrigerated warehouse with a temperature range 32° - 40°F. Surveys were distributed to employees who presently and previously worked in this refrigerated area. The "Picker" and "Feeder" tasks were analyzed as they pertain to this low ...


Measuring Brain Activity Correlates Of Behavior: A Methodological Overview, Curtis K. Deutsch, Stephen Oross Iii, Amanda Difiore, William J. Mcilvane Dec 2000

Measuring Brain Activity Correlates Of Behavior: A Methodological Overview, Curtis K. Deutsch, Stephen Oross Iii, Amanda Difiore, William J. Mcilvane

Eunice Kennedy Shriver Center Publications

The present article was prepared as an introduction to current approaches to studying brain activity correlates of behavior. Our goals are to (1) acquaint readers with current methods for detecting brain activity correlates of behavior and (2) suggest examples of scientific opportunities for collaborative research with brain scientists.


Mechanisms Of Bone Loss In Inflammatory Arthritis: Diagnosis And Therapeutic Implications, Steven R. Goldring, Ellen M. Gravallese Dec 2000

Mechanisms Of Bone Loss In Inflammatory Arthritis: Diagnosis And Therapeutic Implications, Steven R. Goldring, Ellen M. Gravallese

Rheumatology Publications and Presentations

Rheumatoid arthritis represents an excellent model in which to gain insights into the local and systemic effects of joint inflammation on skeletal tissues. Three forms of bone disease have been described in rheumatoid arthritis. These include: focal bone loss affecting the immediate subchondral bone and bone at the joint margins; periarticular osteopenia adjacent to inflamed joints; and generalized osteoporosis involving the axial and appendicular skeleton. Although these three forms of bone loss have several features in common, careful histomorphometric and histopathological analysis of bone tissues from different skeletal sites, as well as the use of urinary and serum biochemical markers ...


Quarantine And Health Screening Protocols For Wildlife Prior To Translocation And Release Into The Wild, Michael H. Woodford Dec 2000

Quarantine And Health Screening Protocols For Wildlife Prior To Translocation And Release Into The Wild, Michael H. Woodford

Other Publications in Zoonotics and Wildlife Disease

In recent years the translocation and release into the wild of wild-caught and captive-bred wild animals (mammals, birds, reptiles, amphibians and fish) has become a common practice, ostensibly for rehabilitation or conservation purposes. These wild animals comprise many varied taxa and the objectives of translocation and release may include:
(1) reintroducing a species that has become extinct in its natural range;
(2) restocking or reinforcing a population which has become depleted; and
(3) rehabilitating wild animals and birds which have been illegally captured and subsequently confiscated by Customs or national wildlife authorities. Welfare organizations also receive sick and injured wild ...


Teams Of One Playing A Losing Game, Rick Burton Dec 2000

Teams Of One Playing A Losing Game, Rick Burton

Sport Management

No abstract provided.


The Regulation Of Nnos During Neuronal Differentiation And The Effect Of Nitric Oxide On Hdm2-P53 Binding: A Dissertation, Christopher M. Schonhoff Dec 2000

The Regulation Of Nnos During Neuronal Differentiation And The Effect Of Nitric Oxide On Hdm2-P53 Binding: A Dissertation, Christopher M. Schonhoff

GSBS Dissertations and Theses

Nitric oxide is a ubiquitous signaling molecule with both physiological and pathological functions in biological systems. Formed by the enzymatic conversion of arginine to citrulline, NO, has known roles in circulatory, immune and nervous tissues. In the nervous system nitric oxide has been implicated in long-term potentiation, neurotransmitter release, channel function, neuronal protection and neuronal degeneration. Much of our work has focused on yet another role for nitric oxide in cells, namely, neuronal differentiation.

During development, neuronal differentiation is closely coupled with cessation of proliferation. We use nerve growth factor (NGF)-induced differentiation of PC12 pheochromocytoma cells as a model ...


The Federal-State Medicaid Match: An Ongoing Tug-Of-War Over Practice And Policy, Karen Matherlee Dec 2000

The Federal-State Medicaid Match: An Ongoing Tug-Of-War Over Practice And Policy, Karen Matherlee

National Health Policy Forum

Reviewing Medicaid match issues since the latter 1980s, this issue brief traces ways in which some states have used creative financing to get more Medicaid matching dollars than they otherwise would qualify for from the federal government. It explores the latest mechanism, states' use of so-called intergovernmental transfers of funds (to avoid established upper payment limits) to increase their matches, triggering efforts by the Senate Finance Committee and the federal Medicaid agency to ban such transfers.


Trends. Terrorism, Terror Management, And Faking Mental Disorder, Editor Dec 2000

Trends. Terrorism, Terror Management, And Faking Mental Disorder, Editor

International Bulletin of Political Psychology

This article highlights the difficulty of determining if defendants on trial are faking mental disorder. The case in question involves the bombing of United States embassies in Kenya and Tanzania.


Impaired Fast-Spiking, Suppressed Cortical Inhibition, And Increased Susceptibility To Seizures In Mice Lacking Kv3.2 K+ Channel Proteins, David Lau, Eleazar Vega-Saenz De Miera, Diego Contreras, Alan Chow, Richard Paylor, Christopher S. Leonard, Bernardo Rudy Dec 2000

Impaired Fast-Spiking, Suppressed Cortical Inhibition, And Increased Susceptibility To Seizures In Mice Lacking Kv3.2 K+ Channel Proteins, David Lau, Eleazar Vega-Saenz De Miera, Diego Contreras, Alan Chow, Richard Paylor, Christopher S. Leonard, Bernardo Rudy

NYMC Faculty Publications

Voltage-gated K(+) channels of the Kv3 subfamily have unusual electrophysiological properties, including activation at very depolarized voltages (positive to -10 mV) and very fast deactivation rates, suggesting special roles in neuronal excitability. In the brain, Kv3 channels are prominently expressed in select neuronal populations, which include fast-spiking (FS) GABAergic interneurons of the neocortex, hippocampus, and caudate, as well as other high-frequency firing neurons. Although evidence points to a key role in high-frequency firing, a definitive understanding of the function of these channels has been hampered by a lack of selective pharmacological tools. We therefore generated mouse lines in which one ...


A Study On The Cellular Localization Of Factors Involved In Yeast Nonsense-Mediated Mrna Decay And Their Mechanisms Of Control On Nonsense Mrna Translation: A Dissertation, Alan Baer Maderazo Dec 2000

A Study On The Cellular Localization Of Factors Involved In Yeast Nonsense-Mediated Mrna Decay And Their Mechanisms Of Control On Nonsense Mrna Translation: A Dissertation, Alan Baer Maderazo

GSBS Dissertations and Theses

Nonsense-mediated mRNA decay (NMD) is an important mRNA surveillance mechanism conserved in eukaryotes. This thesis explores several interesting aspects of the NMD pathway. One important aspect of NMD which is presently the subject of intense controversy is the subcellular localization of NMD. In one set of experiments, the decay kinetics of the ade2-1 and pgk1 nonsense mRNAs (substrates for NMD) were investigated in response to activating the NMD pathway to determine if cytoplasmic nonsense mRNAs are immune to NMD in the yeast system. The results of these studies demonstrated that activation of NMD caused rapid and immediate degradation of both ...


Phosphonated Agents And Their Antiangiogenic And Antitumorigenic Use, Delwood C. Collins, Antonio Gagliardi, Peter Nickel Dec 2000

Phosphonated Agents And Their Antiangiogenic And Antitumorigenic Use, Delwood C. Collins, Antonio Gagliardi, Peter Nickel

Obstetrics and Genecology Faculty Patents

Phosphonic acid agents are synthesized and characterized which are potent inhibitors of angiogenesis, tumorigenesis and metalloproteinase activity. Their method of use for the inhibition of angiogenesis and metalloproteinase and the treatment of tumors is also shown.


Family Duty Is More Important Than Rights, Charles Weijer Dec 2000

Family Duty Is More Important Than Rights, Charles Weijer

Charles Weijer

No abstract provided.


European Madness And Mad Cow Disease, Editor Dec 2000

European Madness And Mad Cow Disease, Editor

International Bulletin of Political Psychology

This article describes some of the psychological factors that might attenuate unadaptive anxieties about the threat of bovine spongiform encephalopathy, mad cow disease.


Development Of A State Wide Tobacco Treatment Specialist Training And Certification Programme For Massachusetts, Lori Pbert, Judith K. Ockene, Beth M. Ewy, Ellen Sachs Leicher, Donna D. Warner Dec 2000

Development Of A State Wide Tobacco Treatment Specialist Training And Certification Programme For Massachusetts, Lori Pbert, Judith K. Ockene, Beth M. Ewy, Ellen Sachs Leicher, Donna D. Warner

Lori Pbert

OBJECTIVE: To describe the research conducted to structure and develop a statewide tobacco training and certification programme for tobacco treatment specialists (TTSs) in Massachusetts. DESIGN: Qualitative research strategies were used to obtain information on certification development and opinions regarding TTS training and certification from key informants. A role definition and validation study was then conducted to determine the core competencies for TTSs. A comprehensive training programme was developed, piloted, and finalised, and a certification programme was initiated. PARTICIPANTS: Key informants included: individuals involved in the development of their professional certification programmes; tobacco treatment providers from across Massachusetts; and national tobacco ...


Development Of A State Wide Tobacco Treatment Specialist Training And Certification Programme For Massachusetts, Lori Pbert, Judith K. Ockene, Beth M. Ewy, Ellen Sachs Leicher, Donna D. Warner Dec 2000

Development Of A State Wide Tobacco Treatment Specialist Training And Certification Programme For Massachusetts, Lori Pbert, Judith K. Ockene, Beth M. Ewy, Ellen Sachs Leicher, Donna D. Warner

Women’s Health Research Faculty Publications

OBJECTIVE: To describe the research conducted to structure and develop a statewide tobacco training and certification programme for tobacco treatment specialists (TTSs) in Massachusetts.

DESIGN: Qualitative research strategies were used to obtain information on certification development and opinions regarding TTS training and certification from key informants. A role definition and validation study was then conducted to determine the core competencies for TTSs. A comprehensive training programme was developed, piloted, and finalised, and a certification programme was initiated.

PARTICIPANTS: Key informants included: individuals involved in the development of their professional certification programmes; tobacco treatment providers from across Massachusetts; and national tobacco ...


Linking Childhood Sexual Abuse And Abusive Parenting: The Mediating Role Of Maternal Anger, David Dilillo, George C. Tremblay, Lizette Peterson Dec 2000

Linking Childhood Sexual Abuse And Abusive Parenting: The Mediating Role Of Maternal Anger, David Dilillo, George C. Tremblay, Lizette Peterson

Faculty Publications, Department of Psychology

Objective: This study had two primary objectives: First, to examine the association between childhood sexual abuse (CSA) and later parenting characteristics, particularly physical abuse potential, and second, to explore maternal anger as a mediator of the relationship between CSA and adult physical abuse potential.

Method: Utilized a community sample of low SES participants that included 138 mothers classified as having experienced CSA, and a comparison group of 152 non-sexually abused mothers. Parenting variables examined included the mothers' physical abuse potential, nurturance toward their children, unrealistic developmental expectations of children, as well as frequencies of spanking and general punishment. Data was ...


Self-Efficacy In Type 2 Diabetics, Joan M. Hyett Dec 2000

Self-Efficacy In Type 2 Diabetics, Joan M. Hyett

Theses & Dissertations

There are 1.2 million diagnosed diabetics in Texas, 10 % of whom live in Bexar County, Texas. Diabetes is rated as the fifth leading cause of death in the same county. In addition to the diagnosed cases, it is estimated that 125,000 adults in Bexar County have undiagnosed diabetes (Foy, 1999). Diabetic education may prevent complications in some individuals, but sometimes knowledge alone is not enough. Patients often lack motivation or self-confidence in their capacity for self- management of their diabetes. Diabetic educators are often faced with the challenge of not only educating but also motivating patients to be ...


Texas D.O. Volume 57, Number 11, Texas Osteopathic Medical Association Dec 2000

Texas D.O. Volume 57, Number 11, Texas Osteopathic Medical Association

Texas Osteopathic Physicians Journal

No abstract provided.