Medicine and Health Sciences Commons^™

Chinese Immigrants With Non-Insulin-Dependent Diabetes Mellitus: Nutritional Self-Management Approach, Winnie Manlai Wong

Student Theses, Dissertations and Capstones

Background: Chinese immigrants (CIs) with non-insulin dependent diabetes mellitus (NIDDM) generally have poor control in their diet regimen. Due to the variation in body mass, physiology, and cultural differences as compare with the general American population, special attention must be conducted in treating diabetes in Cis, emphasizing culturally sensitive care and nutrition therapy that acknowledge the differences. Purpose: The purpose of this project was to assess cultural challenges in self-management for CIs living with non-insulin dependent diabetes mellitus and evaluate the effectiveness of a diabetic nutritional self-management guide tailored to this population. Theoretical Framework: Havelock’s theory of change is a …

Undergraduate Bulletin, 2019-2020, Minnesota State University Moorhead

Undergraduate Bulletins (Catalogs)

No abstract provided.

Part 2: Preparing Entry-Level Occupational And Physical Therapy Students To Promote Healthy Lifestyles Emphasizing Healthy Eating With Individuals With Disabilities, Brooks C. Wingo, Donald H. Lein, Beth A. Barstow, Christopher A. Eidson, Tara S. Pearce, Laurie A. Malone, David M. Morris

Journal of Occupational Therapy Education

Rehabilitation professionals including occupational therapists (OT) and physical therapists (PT) are increasingly called upon to incorporate health promotion of lifestyle behaviors including physical activity and healthy eating into routine clinical care. While OTs and PTs may be comfortable promoting activity-related behaviors, many are less comfortable with nutrition behaviors. To address entry-level OT and PT students’ perceived discomfort with discussing diet-related behaviors, faculty developed a healthy eating module for students to use during a community-based service learning program. The purpose of this paper is to describe the formative evaluation process of developing the healthy eating module, and to discuss results of …

Cortical Stimulation Mapping Of Heschl’S Gyrus In The Auditory Cortex For Tinnitus Treatment, Austin Huang

CMC Senior Theses

Tinnitus is the perception of sound in the absence of an actual sound stimulus. Recent developments have shifted the focus to the central nervous system and the neural correlate of tinnitus. Broadly, tinnitus involves cortical map rearrangement, pathological neural synchrony, and increased spontaneous firing rates. Various cortical regions, such as Heschl’s gyrus in the auditory cortex, have been found to be associated with different aspects of tinnitus, such as perception and loudness. I propose a cortical stimulation mapping study of Heschl’s gyrus using a depth and subdural electrode montage to conduct electrocorticography. This study would provide high-resolution data on abnormal …

Cost Effectiveness Analysis Of Enzalutamide, Abiraterone Plus Prednisone And Cabazitaxel Plus Predinsone For The Treatment Of Visceral Metastatic Castration Resistant Prostate Cancer (Mcrpc) After Docetaxel Therapy, Yazan K. Barqawi

Pharmaceutical Sciences ETDs

Background: Prostate cancer is the second leading cause of death after lung cancer among men in the US. The America Cancer Society predicts 164,690 new cases and 29,430 prostate cancer deaths in 2018. Of those diagnosed with prostate cancer, about 10-20 % will develop castration-resistant prostate cancer (CRPC) within 5 years of diagnosis and 70 % of those cases will metastasize to mCRPC. In 2014, nearly US $13.4 billion was spent on prostate cancer in the US and expected to reach US $15.4 billion by 2020; making prostate cancer the fifth most costly cancer.

Objective: To conduct a cost-effective analysis …

Disparities In Receipt Of A 504 Plan By Socioeconomic Status Among Children Diagnosed With Attention-Deficit/Hyperactivity Disorder (Adhd) In The United States, Ruveni Gogerly-Moragoda, Ingrid Camelo, Lynn Zanardi Blevins, Laurin Kasehagen

Larner College of Medicine Faculty Publications

Disparities in Receipt of a 504 Plan by Socioeconomic Status among Children Diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) in the United States

Abstract

Background

We aimed to understand disparities in the receipt of a 504 Plan among US children with Attention-Deficit/Hyperactivity Disorder (ADHD) using the federal poverty level (FPL) as an indicator of socioeconomic status.

Methods

We analyzed a subpopulation of the 2014 National Survey of the Diagnosis and Treatment of ADHD and Tourette Syndrome (n=2282) children aged 8-17 years. Bivariate and multivariable analyses were used to assess the association of the FPL with receipt of a 504 Plan.

Results

A …

A Systematic Reviewarticle Of Turning Difficulties In Individuals With Stroke, Pei-Yi Chou, Shu-Chun Lee

Rehabilitation Practice and Science

Introduction: Making turn is a challenging task that is reported as one of the activities that most frequently leads to fall in stroke patients. Among community-dwelling older adults, hip fractures are eight times more likely to result from falls while making turns than from falls while walking straight. The stroke patients have asymmetric posture and movements due to hemiparesis, thus their turning performance may varied depending on the direction of the turn. Therefore, the purpose of this systematic reviewarticle was to summarize the characteristics of turning after stroke and discuss the possible neuromuscular mechanisms of turning difficulties. Methods: Searches of …

Comparison Of Laryngeal Excursion In Stroke Patients With And Without Penetration/Aspiration By Videofluoroscopy Swallowing Study, Yun-Fang Lee, Yung-Chun Chi, Shih-Chung Chang

Rehabilitation Practice and Science

Objective: Post-stroke dysphagia is associated with increased morbidity and mortality in acute stroke patients due to malnutrition or aspiration. This study compares the hyolaryngeal movement during swallowing between post-stroke dysphagia patients with and without penetration/aspiration by videofluoroscopy swallowing study (VFSS). The goal was to find out possible defects in swallow mechunism for improving post-stroke dysphagia swallowing training. Method: We retrospectively collected VFSS images from stroke in-patients in a medical center in Central Taiwan from October 2015 to April 2017. The subjects were subdivided according to the VFSS results and 8-point penetration-aspiration scale (PAS) into those with penetration/aspiration (PAS ≥ 3) …

An Acute Non-Traumatic Rib Fracture Detected By Ultrasound And A Reviewarticle Of The Literature, Tze Chao Wee, Chueh-Hung Wu, Tyng-Guey Wang

Rehabilitation Practice and Science

Ultrasound is increasingly used for the diagnosis of musculoskeletal conditions, particularly in soft tissue injuries. In some cases, it is useful for the evaluation of fractures. A 54-year-old woman presented with focal a non-traumatic right-sided chest pain. Physical examination revealed a focal area of tenderness on palpation. Erect chest X-ray was unremarkable. A focused musculoskeletal ultrasound was carried out to examine the area of tenderness and a rib fracture which was not detected on the erect chest X-ray was diagnosed during sonographic examination. A brief literature reviewarticle on the use of ultrasound in the diagnosis of fracture, in particular rib …

Fwer Controlling Procedures In Simultaneous And Selective Inference, Li Yu

Dissertations

With increasing complexity of research objectives in clinical trials, a variety of relatively complex and less intuitive multiple testing procedures (MTPs) have been developed and applied in clinical data analysis. In order to make testing strategies more explicit and intuitive to communicate with non-statisticians, several flexible and powerful graphical approaches have recently been introduced in the literature for developing and visualizing newer MTPs. Nevertheless, some theoretical as well as methodological issues still remain to be fully addressed. This dissertation addresses several important issues arising in graphical approaches and related selective inference problems. It consists of three parts.

In the first …

Functionalized Carbon Nanotubes In Hydrophobic Drug Delivery, Kun Chen

Dissertations

The direct incorporation of carboxylated carbon nanotubes (f-CNTs) into hydrophobic drug particles during their formation via anti-solvent precipitation is presented. The approach is tested using two drugs namely antifungal agent Griseofulvin (GF) and antibiotic Sulfamethoxazole (SMZ) that have very different aqueous solubility. It is observed that the f-CNTs dispersed in the water serve as nucleating sites for crystallization and are readily incorporated into the drug particles without altering crystal structure or other properties. The results show that the hydrophilic f-CNTs dramatically enhance dissolution rate for both drugs. The increased degree of functionalization leads to higher hydrophilicity and therefore faster dissolution …

Patients' Perceptions And Patient-Reported Outcomes In Progressive-Fibrosing Interstitial Lung Diseases, Jeffrey J. Swigris, Kevin K. Brown, Rayid Abdulqawi, Ketan Buch, Daniel F. Dilling, Dirk Koschel, Krishna Thavarajah, Rade Tomic, Yoshikazu Inoue

Internal Medicine Faculty Publications

The effects of interstitial lung disease (ILD) create a significant burden on patients, unsettling almost every domain of their lives, disrupting their physical and emotional well-being and impairing their quality of life (QoL). Because many ILDs are incurable, and there are limited reliably-effective, life-prolonging treatment options available, the focus of many therapeutic interventions has been on improving or maintaining how patients with ILD feel and function, and by extension, their QoL. Such patient-centred outcomes are best assessed by patients themselves through tools that capture their perceptions, which inherently incorporate their values and judgements. These patient-reported outcome measures (PROs) can be …

Patients' Perceptions And Patient-Reported Outcomes In Progressive-Fibrosing Interstitial Lung Diseases, Jeffrey J. Swigris, Kevin K. Brown, Rayid Abdulqawi, Ketan Buch, Daniel F. Dilling, Dirk Koschel, Krishna Thavarajah, Rade Tomic, Yoshikazu Inoue

Internal Medicine Faculty Publications

The effects of interstitial lung disease (ILD) create a significant burden on patients, unsettling almost every domain of their lives, disrupting their physical and emotional well-being and impairing their quality of life (QoL). Because many ILDs are incurable, and there are limited reliably-effective, life-prolonging treatment options available, the focus of many therapeutic interventions has been on improving or maintaining how patients with ILD feel and function, and by extension, their QoL. Such patient-centred outcomes are best assessed by patients themselves through tools that capture their perceptions, which inherently incorporate their values and judgements. These patient-reported outcome measures (PROs) can be …

First-In-Human Phase I Study Of Infusional And Bolus Schedules Of Deflexifol, A Novel 5-Fluorouracil And Leucovorin Formulation, After Failure Of Standard Treatment, Phillip R. Clingan, Stephen Ackland, Daniel Brungs, Paul De Souza, Morteza Aghmesheh, Madhu Garg, Richard Ranson, Suzanne Parker, Rebecca Jokela, Marie Ranson

Illawarra Health and Medical Research Institute

Background: 5‐Fluorouracil (5‐FU) is administered with leucovorin (LV) to enhance clinical activity. However, simultaneous administration is not feasible due to their chemical incompatibility, so conditions for the maximum possible beneficial interaction cannot be met. To overcome this, we developed a novel all‐in‐one, pH neutral stable solution of 5‐FU plus LV with β‐cyclodextrin (termed Deflexifol) and assessed its safety and tolerability in a first‐in‐human phase I trial.

Methods: Patients with advanced solid malignancy received Deflexifol as weekly bolus (375–575 mg/m²) or two‐weekly 46 h infusion (1200–3600 mg/m²) for six cycles in a 3+3 dose escalation design. …

Efficacy Of Low Level Laser Therapy In The Treatment Of Postherpetic Neuralgia, Lili Legiawati, Marsha Bianti

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Postherpetic neuralgia (PHN) is the most common complication of herpes zoster (HZ) and defined as pain that persists for more than 90 days after the onset of HZ rash. The chronic pain of PHN is debilitating and often associated with significant morbidity. It is a neuropathic pain and manifests as allodynia, hyperalgesia, or spontaneous pain. Although it is not considered to be life-threatening, sometime HZ is inadequately treated and may result in more severe PHN. Various treatment protocols for PHN are available; however, the result remains unsatisfactorily. The use of low level laser therapy (LLLT) in pain management …

Return To Work And Health Management In Patients With Work-Related Musculoskeletal Disorder: Literature Reviewarticle, Yi-Chieh Lien, Jang-Ting Wei, Yi-Shiung Horng

Rehabilitation Practice and Science

Work-related musculoskeletal disorders (WRMSDs) are cumulative traumatic disorders that result from work-related ergonomic factors, such as repetitive motion, forceful exertion, awkward posture, holding a vibrating tool, and working in an environment that causes whole-body vibration. These risk factors may induce tendinitis, tenosynovitis, entrapment neuropathy, bursitis, meniscus tear, and even herniation of the lumbar intervertebral disc. WRMSDs may not only affect a patient's health and quality of life but also entail substantial economic and labor costs. Methods for early diagnosis of WRMSDs and management of workplace risk factors must be determined. In addition, vocational rehabilitation should be offered to individuals with …

Effects Of Lidocaine On Migration, Proliferation, Collagen Expression And Cytotoxicity Of Tendon Cells, Hsiang-Ning Chang, Jong-Hwei S Pang, Miao-Sui Lin, Wen-Chung Tsai

Rehabilitation Practice and Science

Background: Lidocaine is commonly used for the treatment of a variety of tendinopathies in combination with corticosteroids injection. Purpose: The goal of this study was to evaluate the effect of lidocaine on migration, proliferation, protein expressions of type I and III collagen and cytotoxicity of tendon cells. Methods: Rat Achilles tendon cells were divided into control and study groups (treated with 0.1%, 0.15%, and 0.2% lidocaine). Tendon cell migration and proliferation were assessed using transwell filter migration assay and MTT assay, respectively. Cytotoxicity of lidocaine was evaluated by the LDH-Cytotoxicity assay. The protein expression of type I and type III …

Hand Temperature And Heart Rate Variability In Stroke Patients When Using Yole Hands And Conventional Elastic Bandages During Passive Upper Limb Exercises, Mei-Yi Lee, Chun-Han Yang, Ko-Long Lin, Shih-Ming Chen, Shu-Shi Chen

Rehabilitation Practice and Science

Therapeutic exercise can mitigate sensorimotor deficit and improve motor function in the upper limbs of stroke patients. During physical rehabilitation, elastic bandages (EB) are often used to secure stroke patients' affected upper limbs to exercise equipment. However, the application of EB can reduce blood flow and lower skin temperature in patients' hands. Furthermore, reduced skin temperature can lead to autonomic nervous reactions, of which heart rate variability (HRV) is an effective indicator. This study investigates the correlation between hand temperature and HRV. Stroke patients' hand temperatures and HRVs were documented during passive upper limb exercises, and the results between the …

Effect Of Aerobic Dance Training In Adults With Prader-Willi Syndrome: A Pilot Study, Fei-Chuan Chen, Shih-Yun Hon, Li-Ping Tsai

Rehabilitation Practice and Science

Objective: Aerobic Dance Training has beneficial effects in improving physical fitness. However, there were few studies validating the physical fitness effectiveness of Aerobic Dance Training in Prader-Willi Syndrome patients (PWS). This study aims to investigate the effects of Aerobic Dance Training in PWS adults, by using integrated clinical measurements of physical fitness. Methods: This is a matched controlled study design. Twelve Prader-Willi Syndrome patients received either Aerobic Dance Training or conventional physiotherapy for 8 weeks (2 times per week for 2 hours each session). Clinical measurements of physical fitness were analyzed before and after the intervention and were followed at …

Experience In Managing Child With Congenital Fiber Type Disproportion With Rehabilitation Outcome: Casereport, Po-Cheng Hsu, Sung-Yin Chuang, Tsui-Fen Yang

Rehabilitation Practice and Science

Congenital fiber type disproportion（CFTD）為一非進行性先天性肌肉病變，須經肌肉切片病理確診，其特點為第一型骨骼肌纖維體積比第二型肌纖維至少小12%。現有文獻提及此疾病之臨床表現變異性大，除肌肉無力，可能併有弓狀顎（High-arched palate）、眼肌麻痺症（Ophthalmoplegia）、呼吸障礙等。患者皆因肌肉無力造成顯著功能障礙。本案例為一10歲確診CFTD男童之長期追蹤與復健介入之描述。患者出生時明顯肌張力不全，自四個月起因生長遲滯、吞嚥功能障礙而接受鼻胃管置入，但診斷未明；後續持續安排物理治療與與語言及吞嚥治療，該患者於一歲八個月時開始走路，三歲時成功移除鼻胃管，並於此時才確診CFTD。患者定期接受完整發展評估，結果顯示明顯動作發展遲緩，其社會心理領域評估結果皆為正常範圍。該患者的肌力與肌耐力隨著年紀增大與物理治療介入而有進步。日常生活能力評估於運動部分仍部分依賴。此外，長期追蹤過程發現該患者有多種肌肉病變之併發症，包括脊柱側彎、雞胸（pectus carinatum）、以及關節與肌肉疼痛。物理治療介入以及教導患者以及家屬運用節省能量之日常生活方式，包括輪椅使用、自我安排活動。本病例報告紀錄CFTD肌病變患者之長期追蹤與復健過程，根據患者之狀況設定個人化復健目標，及處理相關之併發症。

Idiopathic Thoracic Intradural Spinal Arachnoid Cyst Associated With Syringomyelia: A Casereport And Literature Reviewarticle, Jou Yu Lin, Michael Mu Huo Teng, Fu-Kong Lieu, Szu-Fu Chen

Rehabilitation Practice and Science

We report an adult woman who presented with lower limb weakness and dysesthesia caused by a thoracic spinal arachnoid cyst associated with syringomyelia. Before the diagnosis was made by thoracic magnetic resonance imaging, she was diagnosed with lumbar spondylosis and underwent lumbar spinal surgery; however, her symptoms were not relieved. The patient received multilevel laminectomy and cyst resection after thoracic pathology was identified. An upper motor neuron lesion, although rare, should be considered a differential diagnosis when leg symptoms and signs develop. For patients with leg weakness and pain, we emphasize a detailed neurological examination to localize the lesion to …

Domain Rearrangement And Denaturation In Ebola Virus Protein Vp40, Rudramani Pokhrel, Pornthep Sompornpisut, Prem Chapagain, Brian Olson, Bernard Gertsman, Ras B. Pandey

Faculty Publications

The VP40 protein plays a critical role in coordinating the virion assembly, budding, and replication of the Ebola virus. Efforts have been made in recent years to understand various aspects of VP40 structure, dynamics, and function such as assembly of the protein and its roles in virus replication and penetration of the protein into the plasma membrane. A major conformational transformation is necessary for VP40 to form some of its oligomeric structures and to perform various functions. This conformational change from a compact structure with the N-terminal domain (NTD) and C-terminal domain (CTD) closely associated involves a dissociation or springing-out …

Front Matter

Michigan Journal of Public Health

No abstract provided.

Research News. Publications, 2018. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period July 1 through December 31, 2018

What's Happening: December 31, 2018, Maine Medical Center

What's Happening

No abstract provided.

Table Of Contents

Journal of the South Carolina Academy of Science

No abstract provided.

Diagnosing And Treating Diabetes In Rural Jamaica, Emily C. Sims

Scholarship in Medicine - All Papers

Objective: This research study was conducted to determine the correlation between finger stick glucose and finger stick hemoglobin A1c values in order to draw conclusions about the redundancy of the two tests in a rural Jamaican traveling clinic setting. Methods: This study was conducted using de-identified data from an electronic health record used in clinics in St. Mary’s Parish, Jamaica. A correlational analysis was completed using the glucose and A1c variables to determine both the direction and strength of the correlation. Results: A positive correlation of 0.654549 was found in analysis. This correlation did not meet the set threshold for …

The Comprehensive Cancer Control National Partnership Celebrates The 20th Anniversary Of The National Comprehensive Cancer Control Program, National Chair

Michigan Journal of Public Health

No abstract provided.

Full Issue

Michigan Journal of Public Health

No abstract provided.

The Correlation Between Spasticity Of Upper Limbs And Functional Performance In Acute And Subacute Stroke Patients, Wan-Ling Hsu, Pei-Jung Huang, Wei-Hsiu Chang, Chi-Tzu Feng

Rehabilitation Practice and Science

Objective: This study attempted to investigate the correlation between severity of spasticity and functional recovery in acute and subacute stroke patients. Methods: A total of 22 acute and subacute stroke patients were analyzed. Methods used to evaluate outcomes included Modified Ashworth Scale (MAS) for assessing upper limbs spasticity; Fugl-Meyer Assessment (FMA-UE), Box and Block Test (BBT) for assessing the motor ability of upper limbs; Functional Independence Measure (FIM) for assessing independent of daily life, and Stoke Impact Scale (SIS) for evaluating the quality of life. Results: Correlation was found between MAS and FMA-UE (p=.01), BBT (p=.02) and two subtests of …