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1999

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Articles 1 - 30 of 1193

Full-Text Articles in Medicine and Health Sciences

Radiation Therapy For Hemangiosarcoma In A Budgerigar, K Freeman, Kevin Hahn, William Adams, Michael Jones, M Petersen Feb 2013

Radiation Therapy For Hemangiosarcoma In A Budgerigar, K Freeman, Kevin Hahn, William Adams, Michael Jones, M Petersen

William H Adams, DVM, DACVR

A swelling on the right metacarpal area of a male budgerigar was diagnosed as hemangiosarcoma. Diagnosis of this malignant endothelial tumor was based on gross and histopathologic findings. The bird was treated with local irradiation of the wing three times weekly for a total of 10 400-cGy fractions. The tumor completely regressed after local irradiation and the budgerigar tolerated the treatment well; however, the bird died 8 weeks later as a result of disseminated disease. Radiation therapy should be considered as a treatment option in birds with tumors that are unlikely to metastasize or that cannot be completely excised.


A Consortium Developed Poster To Teach Evidence-Based Health Care. (Poster), Kristine Petre, Linda Schwartz Jan 2013

A Consortium Developed Poster To Teach Evidence-Based Health Care. (Poster), Kristine Petre, Linda Schwartz

Linda Matula Schwartz MDE, AHIP, CM

No abstract provided.


Fecal Shedding Of Feline Coronavirus In Adult Cats And Kittens In An Abyssinian Cattery, L Harplod, Alfred Legendre, Melissa Kennedy, Paul Plummer, K Millsaps, Barton Rohrbach Jan 2012

Fecal Shedding Of Feline Coronavirus In Adult Cats And Kittens In An Abyssinian Cattery, L Harplod, Alfred Legendre, Melissa Kennedy, Paul Plummer, K Millsaps, Barton Rohrbach

Melissa A. Kennedy

15 adult cats and 18 kittens from a single cattery were used to determine patterns of faecal shedding of feline coronavirus (FCV). Blood and faecal samples were collected from adult cats every other month for 13 months. Serum FCV antibody titres were measured using an indirect immunofluorescence assay. A reverse-transcriptase, nested polymerase chain reaction assay was used to detect FCV in faeces. Blood and faecal samples were collected from kittens at approximately 2-week intervals from 3 weeks to 15 weeks of age. Adult cats shed FCV intermittently. All adult cats shed virus in their faeces at least once during the ...


Fecal Shedding Of Feline Coronavirus In Adult Cats And Kittens In An Abyssinian Cattery, L Harplod, Alfred Legendre, Melissa Kennedy, Paul Plummer, K Millsaps, Barton Rohrbach Dec 2010

Fecal Shedding Of Feline Coronavirus In Adult Cats And Kittens In An Abyssinian Cattery, L Harplod, Alfred Legendre, Melissa Kennedy, Paul Plummer, K Millsaps, Barton Rohrbach

Alfred M Legendre DVM, MS, DACVIM

15 adult cats and 18 kittens from a single cattery were used to determine patterns of faecal shedding of feline coronavirus (FCV). Blood and faecal samples were collected from adult cats every other month for 13 months. Serum FCV antibody titres were measured using an indirect immunofluorescence assay. A reverse-transcriptase, nested polymerase chain reaction assay was used to detect FCV in faeces. Blood and faecal samples were collected from kittens at approximately 2-week intervals from 3 weeks to 15 weeks of age. Adult cats shed FCV intermittently. All adult cats shed virus in their faeces at least once during the ...


Integration Of Calcium And Cyclic Amp Signaling Pathways By 14-3-3, Chi-Wing Chow, Roger J. Davis Dec 1999

Integration Of Calcium And Cyclic Amp Signaling Pathways By 14-3-3, Chi-Wing Chow, Roger J. Davis

Open Access Articles

Calcium-stimulated nuclear factor of activated T cells (NFAT) transcription activity at the interleukin-2 promoter is negatively regulated by cyclic AMP (cAMP). This effect of cAMP is mediated, in part, by protein kinase A phosphorylation of NFAT. The mechanism of regulation involves the creation of a phosphorylation-dependent binding site for 14-3-3. Decreased NFAT phosphorylation caused by the calcium-stimulated phosphatase calcineurin, or mutation of the PKA phosphorylation sites, disrupted 14-3-3 binding and increased NFAT transcription activity. In contrast, NFAT phosphorylation caused by cAMP increased 14-3-3 binding and reduced NFAT transcription activity. The regulated interaction between NFAT and 14-3-3 provides a mechanism for ...


The Effects Of Anorexia Nervosa On Bone Metabolism In Female Adolescents, Leslie A. Soyka, Steven K. Grinspoon, Lynne L. Levitsky, David B. Herzog, Anne Klibanski Dec 1999

The Effects Of Anorexia Nervosa On Bone Metabolism In Female Adolescents, Leslie A. Soyka, Steven K. Grinspoon, Lynne L. Levitsky, David B. Herzog, Anne Klibanski

Endocrinology/Diabetes

Osteopenia is a frequent, often persistent, complication of anorexia nervosa (AN) in adolescent girls and occurs during a critical time in bone development. Little is known about bone metabolism in this patient population. Therefore, we measured bone density (BMD) and body composition by dual energy x-ray absorptiometry, nutritional status, bone turnover, calcium, and hormonal status in 19 adolescent girls with AN (mean +/- SEM, 16.0+/-0.4 yr) and 19 bone age-matched controls. The mean duration of AN was 19+/-5 months. Spinal (L1-L4) osteopenia was common in AN. Lumbar anterioposterior BMD was more than 1 SD below the mean ...


The Ccaat Displacement Protein/Cut Homeodomain Protein Represses Osteocalcin Gene Transcription And Forms Complexes With The Retinoblastoma Protein-Related Protein P107 And Cyclin A, Maria F. Van Gurp, Jitesh Pratap, Mai X. Luong, Amjad Javed, Heidi M. Hoffmann, Antonio Giordano, Janet L. Stein, Ellis J. Neufeld, Jane B. Lian, Gary S. Stein, Andre J. Van Wijnen Dec 1999

The Ccaat Displacement Protein/Cut Homeodomain Protein Represses Osteocalcin Gene Transcription And Forms Complexes With The Retinoblastoma Protein-Related Protein P107 And Cyclin A, Maria F. Van Gurp, Jitesh Pratap, Mai X. Luong, Amjad Javed, Heidi M. Hoffmann, Antonio Giordano, Janet L. Stein, Ellis J. Neufeld, Jane B. Lian, Gary S. Stein, Andre J. Van Wijnen

Open Access Articles

Developmental control of bone tissue-specific genes requires positive and negative regulatory factors to accommodate physiological requirements for the expression or suppression of the encoded proteins. Osteocalcin (OC) gene transcription is restricted to the late stages of osteoblast differentiation. OC gene expression is suppressed in nonosseous cells and osteoprogenitor cells and during the early proliferative stages of bone cell differentiation. The rat OC promoter contains a homeodomain recognition motif within a highly conserved multipartite promoter element (OC box I) that contributes to tissue-specific transcription. In this study, we demonstrate that the CCAAT displacement protein (CDP), a transcription factor related to the ...


He’S The Top Sports Marketer In 1,000 Years, Rick Burton Dec 1999

He’S The Top Sports Marketer In 1,000 Years, Rick Burton

Sport Management

No abstract provided.


Faculty And Student Perceptions Of Effective Clinical Teachers, Patricia Frontczak Dec 1999

Faculty And Student Perceptions Of Effective Clinical Teachers, Patricia Frontczak

Masters Theses

The purpose of this study was to identify ADN faculty and ADN student perceptions of the most effective clinical teaching characteristics (ECTC). An exploratory, descriptive design was implemented. ADN faculty and ADN students were surveyed using the Clinical Teacher Characteristics Instrument (CTCI). The CTCI consists of 20 characteristics of clinical teachers that are ranked on a five point Likert-type scale according to importance. The collected data were analyzed using descriptive statistics. Significant differences in perceptions of the most ECTC between the two groups were identified by a Mann Whitney U procedure. A t-test was performed to identify differences of perceptions ...


Identification Of The Human Erythrocyte Glucose Transporter (Glut1) Atp Binding Domain: A Dissertation, Kara B. Levine Dec 1999

Identification Of The Human Erythrocyte Glucose Transporter (Glut1) Atp Binding Domain: A Dissertation, Kara B. Levine

GSBS Dissertations and Theses

The human erythrocyte glucose transport protein (GLUT1) interacts with, and is regulated by, cytosolic ATP. This study asks the following questions concerning ATP modulation of GLUT1 mediated sugar transport. 1) Which region(s) of GLUT1 form the adenine nucleotide-binding domain? 2) What factors influence ATP modulation of sugar transport? 3) Is ATP interaction with GLUT1 sufficient for sugar transport regulation?

The first question was addressed through peptide mapping, n-terminal sequencing, and alanine scanning mutagenesis of GLUT1 using [32P]-azidoATP, a photoactivatable ATP analog. We then used a combination of transport measurements and photolabeling strategies to examine how glycolytic intermediates ...


Spin Trapping Pharmaceutical Compositions And Methods For Use Thereof, John M. Carney, Robert A. Floyd Dec 1999

Spin Trapping Pharmaceutical Compositions And Methods For Use Thereof, John M. Carney, Robert A. Floyd

Pharmacology and Nutritional Sciences Faculty Patents

Spin trapping compositions in general have now been discovered to be effective in treating a variety of disorders, including disorders such as those arising from ischemia, infection, inflammation, exposure to radiation or cytotoxic compounds, not just of the central and peripheral nervous systems but of peripheral organ disease having a wide variety of etiologies. In the preferred embodiment, the compositions for treating tissue damage from ischemia contain PBN, or active derivatives thereof, in a suitable pharmaceutical carrier for intravenous, oral, topical, or nasal/pulmonary administration. Other preferred spin-trapping agents include 5,5-dimethyl pyrroline N-oxide, (DMPO), α-(4-pyridyl-1-oxide)-N-tert-butylnitrone, (POBN), and ...


Transcriptional Silencing Elements And Their Binding Factors, Joseph Chappell, Jeffrey D. Newman, Shaohui Yin Dec 1999

Transcriptional Silencing Elements And Their Binding Factors, Joseph Chappell, Jeffrey D. Newman, Shaohui Yin

Pharmaceutical Sciences Faculty Patents

The invention features an isolated gene silencing regulatory element that includes 5' TACNNTAC 3'. Vectors, transgenic plants and seeds thereof that include such a gene silencing regulatory element are also disclosed. The invention further provides methods of decreasing the transcription of a DNA sequence in a transgenic plant using the isolated gene silencing regulatory element.


Implantable Controlled Release Device To Deliver Drugs Directly To An Internal Portion Of The Body, Paul Ashton, Paul A. Pearson Dec 1999

Implantable Controlled Release Device To Deliver Drugs Directly To An Internal Portion Of The Body, Paul Ashton, Paul A. Pearson

Ophthalmology and Visual Science Faculty Patents

A simple and implantable sustained release drug delivery device with an inner core containing an effective amount of a low solubility agent covered by a non-bioerodible polymer coating layer that is permeable to the low solubility agent is disclosed. A method for treating a mammal to obtain a desired local or systemic physiological or pharmacological effect by surgically implanting such a sustained release drug delivery device into a mammal in need of treatment is also disclosed.


Trends. Drug Addictions: National Policy On Illicit Drugs, Editor Dec 1999

Trends. Drug Addictions: National Policy On Illicit Drugs, Editor

International Bulletin of Political Psychology

The article discusses the proposed integrating of drug testing and treatment into the various phases of the criminal justice process.


Recommendations For Standards Regarding Preclinical Neuroprotective And Restorative Drug Development Dec 1999

Recommendations For Standards Regarding Preclinical Neuroprotective And Restorative Drug Development

Open Access Articles

The plethora of failed clinical trials with neuroprotective drugs for acute ischemic stroke have raised justifiable concerns about how best to proceed for the future development of such interventions. Preclinical testing of neuroprotective drugs is an important aspect of assessing their therapeutic potential, but guidelines concerning how to perform preclinical development of purported neuroprotective drugs for acute ischemic stroke are lacking. This conference of academicians and industry representatives was convened to suggest such guidelines for the preclinical evaluation of neuroprotective drugs and to recommend to potential clinical investigators the data they should review to reassure themselves that a particular neuroprotective ...


Analysis Of Cell Polarity Signaling In C. Elegans: A Dissertation, Christian Ernest Rocheleau Dec 1999

Analysis Of Cell Polarity Signaling In C. Elegans: A Dissertation, Christian Ernest Rocheleau

GSBS Dissertations and Theses

During embryonic development of the nematode Caenorhabditis elegans, cell fates are specified by asymmetric segregation of cell fate determinants and via cell-cell signaling events. Specification of the eight-cell stage blastomere E, the endoderm progenitor cell, requires both cell signaling and asymmetric cell division. At the four-cell stage, a polarity-inducing signal from the P2 cell is required for the EMS cell to divide asymmetrically to produce an anterior daughter MS, and posterior daughter E. In the absence of signal, the EMS cell divides symmetrically to produce two daughters that adopt the MS fate. This thesis describes the identification and analyses ...


Occupational Therapists' Interests And Attitudes Toward Animal Assisted Therapy As A Treatment Modality, Lori Susan Buckley Dec 1999

Occupational Therapists' Interests And Attitudes Toward Animal Assisted Therapy As A Treatment Modality, Lori Susan Buckley

FIU Electronic Theses and Dissertations

One hundred seventy-nine occupational therapists (OTs) responded to a survey regarding their interests and attitudes toward animal assisted therapy as a treatment modality. It was found that most of the practitioners would be interested in learning more about animal assisted therapy and most felt it is a valid treatment modality to be used by occupational therapists. Furthermore, the most common answer to the question "why would you not be interested in participating in an AAT program," was "I feel I don't know enough about it". It was also found that therapists' most commonly selected patient goals for AAT were ...


Air Pollution And Health: What The Georgia Physician Should Know, Pamela Meyer, David Mannino, Stephen Redd Dec 1999

Air Pollution And Health: What The Georgia Physician Should Know, Pamela Meyer, David Mannino, Stephen Redd

David M. Mannino

No abstract provided.


Stress Experienced By Respite Care Workers And Family Caregivers When Caring For Alzheimer's Patients, Monica D. Minewiser Dec 1999

Stress Experienced By Respite Care Workers And Family Caregivers When Caring For Alzheimer's Patients, Monica D. Minewiser

Theses & Dissertations

Changing demographics and cost containment in health care in caring for the Alzheimer's Disease (AD) patient has given birth to a growing need for respite care workers. The purpose of the study was to determine whether the stress level of a respite care worker who works with an AD patient in a noninstitutionalized setting on a daily basis will be significantly less than that of a family caregiver when caring for an AD patient. The Revised Memory and Behavior Problem Checklist (RMBPC) was the instrument used to measure stress. This is a questionnaire consisting of 24 questions and allows ...


The Nature Of Collegial Relationships In Nursing: Perceptions Of Novice Practitioners, Kathleen Knaack Dec 1999

The Nature Of Collegial Relationships In Nursing: Perceptions Of Novice Practitioners, Kathleen Knaack

Master's Theses, Capstones, and Projects

The purpose of this study was to examine the relationship development, the level of support afforded, and the communication style of novice nurses. This study was chosen to assist with clarification of the concept that nurses "eat their young". The study was conducted in a metropolitan health care system in the mid-west with participants from a variety of settings within this system, including acute care and community service. Participants were volunteers from a convenience sample, all with less than eighteen months of experience. The study utilized a qualitative research methodology with semi-structured interviews employed to collect data. The study was ...


Texas D.O. Volume 56, Number 11, Texas Osteopathic Medical Association Dec 1999

Texas D.O. Volume 56, Number 11, Texas Osteopathic Medical Association

Texas Osteopathic Physicians Journal

No abstract provided.


Developing Augmentative Communication To Support Participation In General Education Classrooms, Michael Mcsheehan, Rae M. Sonnenmeier Dec 1999

Developing Augmentative Communication To Support Participation In General Education Classrooms, Michael Mcsheehan, Rae M. Sonnenmeier

Institute on Disability

No abstract provided.


Officer Involved Shooting: The Emotional Impact And The Effective Coping Strategies, Patrick P. Charoen Dec 1999

Officer Involved Shooting: The Emotional Impact And The Effective Coping Strategies, Patrick P. Charoen

UNLV Theses, Dissertations, Professional Papers, and Capstones

The emotional impact of a shooting incident on the individual police officer has been recognized and detailed by both police and mental health professionals (Lippert & Ferrara, 1984). The human cost and financial costs to Police Departments as a result of "post shooting" trauma has sensitized many departments to the need for professional support for officers involved in shootings. Recent survey research has provided information about the percentage of officers who experienced great, moderate, or no emotional impact after being involved in shootings (Stratton, 1982). However, information about the degree to which police departments have responded to this need has been ...


Update - December 1999, Loma Linda University Center For Christian Bioethics Dec 1999

Update - December 1999, Loma Linda University Center For Christian Bioethics

Update

In this issue:

-- John and Alice Wong establish bioethics endowment
-- Richard Rice receives Templeton Award
-- "Humans" and "Persons" in Christian Bioethics (Commentary)
-- Mechanically Restraining the Ill and Elderly: Ethical Problems and Proposals
-- Clinical Ethics Consultation
-- Learn to minister in the clinical setting


P53 Inhibits Alpha 6 Beta 4 Integrin Survival Signaling By Promoting The Caspase 3-Dependent Cleavage Of Akt/Pkb, Robin E. Bachelder, Mark J. Ribick, Alessandra Marchetti, Rita Falcioni, Silvia Soddu, Kathryn R. Davis, Arthur M. Mercurio Dec 1999

P53 Inhibits Alpha 6 Beta 4 Integrin Survival Signaling By Promoting The Caspase 3-Dependent Cleavage Of Akt/Pkb, Robin E. Bachelder, Mark J. Ribick, Alessandra Marchetti, Rita Falcioni, Silvia Soddu, Kathryn R. Davis, Arthur M. Mercurio

Cancer Biology Publications and Presentations

Although the interaction of matrix proteins with integrins is known to initiate signaling pathways that are essential for cell survival, a role for tumor suppressors in the regulation of these pathways has not been established. We demonstrate here that p53 can inhibit the survival function of integrins by inducing the caspase-dependent cleavage and inactivation of the serine/threonine kinase AKT/PKB. Specifically, we show that the alpha6beta4 integrin promotes the survival of p53-deficient carcinoma cells by activating AKT/PKB. In contrast, this integrin does not activate AKT/PKB in carcinoma cells that express wild-type p53 and it actually stimulates their ...


Extensive Conservation Of Sex Chromosome Organization Between Cat And Human Revealed By Parallel Radiation Hybrid Mapping, William J. Murphy, Shan Sun, Zhang-Qun Chen, Jill Pecon-Slattery, Stephen J. O'Brien Dec 1999

Extensive Conservation Of Sex Chromosome Organization Between Cat And Human Revealed By Parallel Radiation Hybrid Mapping, William J. Murphy, Shan Sun, Zhang-Qun Chen, Jill Pecon-Slattery, Stephen J. O'Brien

Biology Faculty Articles

A radiation hybrid (RH)-derived physical map of 25 markers on the feline X chromosome (including 19 Type I coding loci and 6 Type II microsatellite markers) was compared to homologous marker order on the human and mouse X chromosome maps. Complete conservation of synteny and marker order was observed between feline and human X chromosomes, whereas the same markers identified a minimum of seven rearranged syntenic segments between mouse and cat/human X chromosome marker order. Within the blocks, the feline, human, and mouse marker order was strongly conserved. Similarly, Y chromosome locus order was remarkably conserved between cat ...


Bacterial Diseases (Field Manual Of Wildlife Diseases), Milton Friend Dec 1999

Bacterial Diseases (Field Manual Of Wildlife Diseases), Milton Friend

Other Publications in Zoonotics and Wildlife Disease

Diseases caused by bacteria are a more common cause of mortality in wild birds than are those caused by viruses. In addition to infection, some bacteria cause disease as a result of potent toxins that they produce. Bacteria of the genus Clostridium are responsible for more wild bird deaths than are other disease agents. Clostridium botulinum, which causes avian botulism, is primarily a form of food poisoning and it is included within the section on biotoxins (see Chapter 38). Other Clostridium sp. that colonize intestinal tissues produce toxins that cause severe hemorrhaging of the intestine, thus leading to tissue death ...


Appendices, Glossary, And Index (Field Manual Of Wildlife Diseases) Dec 1999

Appendices, Glossary, And Index (Field Manual Of Wildlife Diseases)

Other Publications in Zoonotics and Wildlife Disease

A. Sample specimen history form
B. Sources of wildlife diagnostic assistance in the United States
C. Sources of supplies used for collecting, preserving, and shipping specimens
D. Normal brain cholinesterase activity values
E. Common and scientific names of birds in text
F. Common and scientific names other than birds
G. Chemical names
H. Conversion table

Glossary
Index

REPORT DOCUMENTATION PAGE


Field Manual Of Wildlife Diseases: General Field Procedures And Diseases Of Birds, Milton Friend, J. Christian Franson Dec 1999

Field Manual Of Wildlife Diseases: General Field Procedures And Diseases Of Birds, Milton Friend, J. Christian Franson

Other Publications in Zoonotics and Wildlife Disease

The “Field Manual of Wildlife Diseases: General Field Procedures and Diseases of Birds” presents practical, current information and insights about wild bird illnesses and the procedures to follow when ill birds are found or epidemics occur. Section 1 of the Manual provides information about general field procedures. Sections 2 through 5 describe various bird diseases. Sections 6 and 7 provide information about toxins that affect birds, and Section 8 describes miscellaneous diseases and hazards that affect birds. Manual lists institutions and laboratories that offer diagnostic services; sources of supplies for collecting, preserving, and shipping specimens; and it contains color illustrations ...


Introduction To General Field Procedures (Field Manual Of Wildlife Diseases), J. Christian Franson, Milton Friend, Dale E. Toweill, Robert L. Brownell Jr., Victor F. Nettles, Donald S. Davis, William J. Foreyt Dec 1999

Introduction To General Field Procedures (Field Manual Of Wildlife Diseases), J. Christian Franson, Milton Friend, Dale E. Toweill, Robert L. Brownell Jr., Victor F. Nettles, Donald S. Davis, William J. Foreyt

Other Publications in Zoonotics and Wildlife Disease

Section 1 of the Manual provides basic information regarding general field procedures for responding to wildlife disease events. Field biologists provide a critical linkage in disease diagnostic work and greatly affect the outcome of the laboratory efforts by the quality of the materials and information that they provide. The chapters in this section are oriented towards providing guidance that will assist field biologists in gathering the quality of information and specimens that are needed. Readers will find information regarding what to record and how; guidance for specimen collection, preservation, and shipment; and how to apply euthanasia when such actions are ...