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2020

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Articles 1 - 30 of 18467

Full-Text Articles in Medicine and Health Sciences

Outcomes Of Telepractice Speech Therapy For An Adult Who Covertly Stutters: A Case Study, Megann Mcgill, Patrizha A. Schroth Dec 2020

Outcomes Of Telepractice Speech Therapy For An Adult Who Covertly Stutters: A Case Study, Megann Mcgill, Patrizha A. Schroth

PSU McNair Scholars Online Journal

Purpose: To report on telepractice-based holistic speech-language therapy services to reduce avoidance of stuttering and increase positive self-image as a communicator for an adult who covertly stutters as compared to baseline.

Method: A single case study design was employed with baseline, intervention, and maintenance phases completed via telepractice. The participant received bi-weekly speech-language therapy services, including both individual and group sessions. The Overall Assessment of the Speaker’s Experience of Stuttering-Adult (OASES-A) and Stuttering Severity Instrument-4th Edition (SSI-4) assessed the participant’s overt and covert stuttering behaviors at pre-treatment and post-treatment timeframes. Weekly data points of participant’s self-report of ...


We’Re All On This Spaceship Earth, Nancy Si Dec 2020

We’Re All On This Spaceship Earth, Nancy Si

HCA Healthcare Journal of Medicine

The photo features the geodesic sphere at Epcot, Disney World in Orlando, FL. Inside the dome, there was an iconic ride called “Spaceship Earth”, which has since been shut down for refurbishment. This photo was taken November 2019, approximately 6 months before it was shut down. Much like how the ride emphasized the progress that human civilization has made in the last several hundred years and hopes to make in years to come, the current pandemic has shown us how far we have come in the medicine and other STEM fields. We hope only to do better and be better ...


Still Learning: Covid Through The Eyes Of A Medical Student, Alexis Strahan Dec 2020

Still Learning: Covid Through The Eyes Of A Medical Student, Alexis Strahan

HCA Healthcare Journal of Medicine

As a first-year medical student when the COVID-19 pandemic found a foothold, I felt an overwhelming amount of emotions that accompanied the pandemic’s spread. Fear, although a reasonable choice, was not the first emotion that I experienced. In fact, it was a general feeling of paralysis. I had not six months prior taken an oath to commit my career and life to the service of the public’s health care needs, yet I could provide little more than the textbook knowledge of biochemistry or genetics from my first semester of learning. My hands felt unarmed and unskilled for the ...


Effect Of An Electronic Order Set On Newborn Hepatitis B Immunization Rates, Daniel Pedersen, Angelina Rodriguez, Olu Oyesanmi, Heather Schramm, Michael King Dec 2020

Effect Of An Electronic Order Set On Newborn Hepatitis B Immunization Rates, Daniel Pedersen, Angelina Rodriguez, Olu Oyesanmi, Heather Schramm, Michael King

HCA Healthcare Journal of Medicine

Objective

Hepatitis B is an infectious deoxyribonucleic acid virus which can cause significant morbidity and mortality. There is no current definitive treatment, however in the United States immunization is widely available. A paper published by the Advisory Committee on Immunization Practices/Centers for Disease Control (ACIP/CDC) in 2018 made updated recommendations regarding vaccination practices in the United States. The most notable change made was that all healthy newborns weighing ≥2000 g with a negative hepatitis B-status mother should receive hepatitis B immunization within 24 hours of birth. This quality improvement project studied the effect of the electronic medical record ...


Magic Medicine, Bruce St. Amour, William B. Dehart Dec 2020

Magic Medicine, Bruce St. Amour, William B. Dehart

HCA Healthcare Journal of Medicine

Background

A superstition is a belief or practice that is considered irrational, resulting from ignorance, fear of the unknown, trust in magic or chance or a false conception of causation. In medical settings superstitions often arise from attempts to assign causation to events that are either random, or in which all information is not available. In this manuscript, we present a descriptive review of the literature related to superstition in medicine and present the results of our own data; that one’s age is equal to the chance of being admitted from the emergency department.

Methods

In the descriptive review ...


Case Of Enterococcus Cecorum Human Bacteremia, United States, Alexander D. Lake, Ryan Fields, Francia Guerrero, Yousef Almuzaini, Koravangala Sundaresh, Joseph Staffetti Dec 2020

Case Of Enterococcus Cecorum Human Bacteremia, United States, Alexander D. Lake, Ryan Fields, Francia Guerrero, Yousef Almuzaini, Koravangala Sundaresh, Joseph Staffetti

HCA Healthcare Journal of Medicine

Enterococcus cecorum rarely serves as a human pathogen, and only 6 cases of this microbe inoculating humans have been documented. We present an elderly female with a marked vascular history presenting with epigastric pain and diarrhea, followed by shaking chills. Laboratory findings revealed leukocytosis, with imaging showing diffuse colonic thickening. She had a bout of bloody diarrhea, raising the likelihood of ischemic colitis with her vascular history. To our surprise, both sets of blood cultures drawn on admission grew Enterococcus cecorum. This case is unique as it is the first documented case of E. cecorum human infection in the United ...


Goblet Cell Carcinoma Of The Appendix: A Case Report On Goblet Cell Carcinoid, Sheliza Kabani, Aubtin Saedi, Austin Lehr, Lina O'Brien Dec 2020

Goblet Cell Carcinoma Of The Appendix: A Case Report On Goblet Cell Carcinoid, Sheliza Kabani, Aubtin Saedi, Austin Lehr, Lina O'Brien

HCA Healthcare Journal of Medicine

Goblet cell carcinoid of the appendix is a rare neoplasm with histological features of both neuroendocrine and adenocarcinomas. The combination of its aggressive behavior, infrequent occurrence, and variable clinical presentation convolutes the management of this tumor. We report the case of a 75-year-old female presenting with acute appendicitis. A laparoscopic appendectomy was performed. The pathology report showed goblet cell carcinoid at the base of the appendix with involvement of the proximal surgical margins. At her postoperative visit, the patient’s pathology report and options for management were reviewed, and the patient agreed to proceed with a right hemicolectomy 8-10 weeks ...


A Rare Case Of C3 Glomerulonephritis Presenting As Pulmonary Renal Syndrome, Gerardo Mederos, Harsh Patel, Menalee Hapuarachchi, Machaiah Madhrira, Ranjit Nair, Dana Ciobanu Dec 2020

A Rare Case Of C3 Glomerulonephritis Presenting As Pulmonary Renal Syndrome, Gerardo Mederos, Harsh Patel, Menalee Hapuarachchi, Machaiah Madhrira, Ranjit Nair, Dana Ciobanu

HCA Healthcare Journal of Medicine

C3 glomerulonephritis (C3GN) is a rare disease that falls under the umbrella of C3 glomerulopathy (C3G). Classic manifestations of C3G include acute renal failure, proteinuria, and hematuria. In some cases, extrarenal manifestations can include ocular drusen. Until recent reports, C3G manifesting with pulmonary symptoms has not been reported. In this report, we describe a patient that initially presented with hemoptysis and acute renal failure, eventually leading to a diagnosis of pulmonary renal syndrome. Renal biopsy showed C3GN. The patient’s symptoms improved with pulse dose steroids, plasmapheresis and mycophenolate mofetil. C3G presenting with pulmonary symptoms is rare. Further research is ...


A Case Of Simpson-Golabi-Behmel Syndrome Presenting With Cutaneous Findings, Tessa Mullins, Abigail Russell, Chad Johnston Dec 2020

A Case Of Simpson-Golabi-Behmel Syndrome Presenting With Cutaneous Findings, Tessa Mullins, Abigail Russell, Chad Johnston

HCA Healthcare Journal of Medicine

Simpson-Golabi-Behmel syndrome is a rare, X-linked recessive syndrome associated with mutations in the genes encoding glypican 3 (GPC3). The majority of cases have been described in pediatric males, with those affected showing manifestations of overgrowth, congenital heart defects, and increased incidence of neoplasia. Due to the X-linked nature of this disorder, penetrance is not well understood in female cases. Very few cases of female presentations of Simpson-Golabi-Behmel syndrome have been described, and this case highlights that there may be an association between mutated GPC3 carrier status and other cancers. We present a case of GPC3 gene mutation suggestive of Simpson-Golabi-Behmel ...


Cutaneous Malignant Melanoma: A Synthesis On Updated Guidelines For The Primary Care Perspective, Seetha Venkateswaran, Nicholas D'Angelo Dec 2020

Cutaneous Malignant Melanoma: A Synthesis On Updated Guidelines For The Primary Care Perspective, Seetha Venkateswaran, Nicholas D'Angelo

HCA Healthcare Journal of Medicine

Cutaneous malignant melanoma (CMM) is a condition wherein malignant cells form in the melanocytic cells. CMM is a potentially lethal form of skin cancer, commonly found in sun-exposed areas of the body. There are multiple risk factors for disease development, such as genetic mutation and UV radiation among others. Diagnosis and staging is important in determining disease morbidity and mortality. The United States Preventive Services Task Force (USPSTF) and the American Academy of Dermatology (AAD) have their respective guidelines and consensus on diagnosis, staging and treatment. It is imperative to delineate and educate primary care physicians on CMM, as they ...


Covid-19: Race For Vaccine, L. Hayley Burgess, Jason J. Braithwaite, Emily Singleton, Aaron M. Young, Mandelin K. Cooper Dec 2020

Covid-19: Race For Vaccine, L. Hayley Burgess, Jason J. Braithwaite, Emily Singleton, Aaron M. Young, Mandelin K. Cooper

HCA Healthcare Journal of Medicine

The world is in the midst of a pandemic from COVID-19, a disease caused by the virus SARS-CoV-2. Despite broad mitigation efforts, new cases continue with 74 million cases and 1.6 million deaths worldwide. Regardless of previous research efforts, there is no commercially available vaccine for any coronavirus. Novel vaccine development has historically taken at least 10 years from discovery to availability with only a 6% market entry probability.

With the global impact, there is an urgency to expedite a vaccine to protect the population. The U.S. government launched Operation Warp Speed with the goal to produce and ...


Importance Of Awareness Of Adverse Drug Reaction Reporting During The Covid-19 Pandemic, Heather Ellis, Hale Z. Toklu Dec 2020

Importance Of Awareness Of Adverse Drug Reaction Reporting During The Covid-19 Pandemic, Heather Ellis, Hale Z. Toklu

HCA Healthcare Journal of Medicine

Health care professionals hold the responsibility of reporting any adverse drug reactions in order to learn about new therapy and how best to safely care for our patients. The information derived from case publications and FDA MedWatch reports are essential to accumulate information and increase awareness for the possible risks of new drugs.


The Relationship Between Narrative Informativeness And Psychosocial Outcomes In Chronic Stroke-Induced Aphasia, Eileen Armes, Jessica Richardson, Rick Arenas, Lori Nelson Dec 2020

The Relationship Between Narrative Informativeness And Psychosocial Outcomes In Chronic Stroke-Induced Aphasia, Eileen Armes, Jessica Richardson, Rick Arenas, Lori Nelson

Speech and Hearing Sciences ETDs

Currently there is a gap in the literature in understanding the relationship between the newly categorized primary outcome measure of discourse and secondary outcomes related to psychosocial impact, such as participation, psychological impact, social well-being, or mood. In a large sample of persons with stroke-induced aphasia (N=115), this study analyzed discourse samples using main concept analysis to determine how discourse performance correlates with the secondary outcome measures ALA, CCRSA, GDS, and CIQ. As a secondary research question, the differences in these relationships dependent on severity was also explored. Results showed statistically significant positive correlations between main concepts (MCs) and ...


Use Of A Cancer Registry To Evaluate Patient-Reported Outcomes Of Immune Checkpoint Inhibitors., Heather S L Jim, Sarah L Eisel, Aasha I Hoogland, Sandra Shaw, Jennifer C King, Adam P Dicker Dec 2020

Use Of A Cancer Registry To Evaluate Patient-Reported Outcomes Of Immune Checkpoint Inhibitors., Heather S L Jim, Sarah L Eisel, Aasha I Hoogland, Sandra Shaw, Jennifer C King, Adam P Dicker

Department of Radiation Oncology Faculty Papers

Immune checkpoint inhibitors (ICIs) are increasingly used for advanced lung cancer, butfew studies have reported on patient-reported outcomes (PROs) outside the context of a clinicaltrial. The goal of the current study was to assess PROs in participants of a lung cancer registry whohad been treated with an ICI. Patients participating in the GO2Foundation’s Lung Cancer Registrywho reported receiving atezolizumab, durvalumab, nivolumab, or pembrolizumab were invited toparticipate in a survey about their experiences during treatment. Quality of life was evaluated usingthe Functional Assessment of Cancer Therapy–General (FACT-G). Common symptomatic adverseevents were evaluated using an item bank generated for ICIs ...


Research News. Publications, 2020. Volume 4, Soumyajit Majumdar Dec 2020

Research News. Publications, 2020. Volume 4, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period October 1 through December 31, 2020


Inhibitory And Anti-Biofilm Effects Of Orthoshipon Aristatus Against Candida Albicans, Ratika Rahmasari, Ananda Hanny Chairunissa, Marina Ika Irianti, Roshamur Cahyan Forestrania, Ayun Erwina Arifianti, Herman Suryadi, Juliann Nzembi Makau, Ibrahim Jantan, Berna Elya Dec 2020

Inhibitory And Anti-Biofilm Effects Of Orthoshipon Aristatus Against Candida Albicans, Ratika Rahmasari, Ananda Hanny Chairunissa, Marina Ika Irianti, Roshamur Cahyan Forestrania, Ayun Erwina Arifianti, Herman Suryadi, Juliann Nzembi Makau, Ibrahim Jantan, Berna Elya

Pharmaceutical Sciences and Research

There are increasing number of reports on Candida albicans developing resistance to available anti-fungal drugs. Thus, there is an urgent need to discover new agents for treatment of candidiasis. The alcoholic extracts of Orthoshipon aristatus have been shown to exhibit antifungal activity against C. albicans by using the agar diffusion and broth microdilution methods. However, the underlying mechanisms of anti-C. albicans effect of O. aristatus have not been well understood. This study was aimed to evaluate the cytotoxic and anti-biofilm effects of the n-hexane and ethanol extracts of purple and white varieties of O. aristatus leaves and branches against ...


Antifungal Activity Of Polyscias Scutellaria Fosberg Leaves Against Candida Albicans, Nada Marcha Putri, Jasmine Regita Putri, Berna Elya, Robiatul Adawiyah Dec 2020

Antifungal Activity Of Polyscias Scutellaria Fosberg Leaves Against Candida Albicans, Nada Marcha Putri, Jasmine Regita Putri, Berna Elya, Robiatul Adawiyah

Pharmaceutical Sciences and Research

Polyscias scutellaria Fosberg is one of the indigenous plants from Indonesia that widely used as folk medicines for several illnesses. The leaves of P. scutellaria were previously studied as an antimicrobial agent. Nonetheless, this theory of antifungal activity has never been scientifically verified. This study aimed to evaluate the antifungal activity of P. scutellaria against Candida albicans. The leaves of P. scutellaria were macerated using an ethanol solvent. Then, the extract was evaporated and dissolved by 1% DMSO into different concentrations (100 μg/mL, 200 μg/mL, 400 μg/mL, 800 μg/mL, 1600 μg/mL, 3200 μg/mL, and ...


Fractionation Of Citronella Oil And Identification Of Compounds By Gas Chromatography-Mass Spectrometry, Yelfi Anwar, Victor S. Siringoringo Dec 2020

Fractionation Of Citronella Oil And Identification Of Compounds By Gas Chromatography-Mass Spectrometry, Yelfi Anwar, Victor S. Siringoringo

Pharmaceutical Sciences and Research

Citronella oil is one of the most important essential oils and is widely used in the pharmaceutical, cosmetic and food industries. However, the selling price of citronella oil is still low, so efforts are needed to increase its added value by isolating the active components such as citronellal, citronellol and geraniol. This study aims to isolate the active ingredients of citronella oil that have higher economic added value. Citronella oil was obtained by the process of distillation of Cymbopogon nardus (L.) Rendle leaves. The essential oil was then fractionated by a vacuum fractionation process. The essential oil fraction was identified ...


The Anti-Proliferation Effect Of An Isolated Butanol Fraction Of Tampa Badak (Voacanga Foetida (Bl.) K. Schum) Leaves On Leukemia, Lung, And Cervical Cancer, Adriani Susanty, Dachriyanus Dachriyanus, Yanwirasti Yanwirasti, Fatma Sri Wahyuni, Andisyah Putri Sekar, Nur Alimin, Magdazaleni Magdazaleni, Sri Esky Sofia, Citra Kartika Dewi Dec 2020

The Anti-Proliferation Effect Of An Isolated Butanol Fraction Of Tampa Badak (Voacanga Foetida (Bl.) K. Schum) Leaves On Leukemia, Lung, And Cervical Cancer, Adriani Susanty, Dachriyanus Dachriyanus, Yanwirasti Yanwirasti, Fatma Sri Wahyuni, Andisyah Putri Sekar, Nur Alimin, Magdazaleni Magdazaleni, Sri Esky Sofia, Citra Kartika Dewi

Pharmaceutical Sciences and Research

Voacanga foetida (Bl.) K.Schum leaves are known to have cytotoxic activity against blood cancer cells. This study was aimed to determine the potential of an isolated butanol fraction of Voacanga foetida (Bl.) K.Schum leaves (Tb3 compound) in inhibiting the proliferation of several cancer cells, including leukemia (K562), lung cancer (A549), and cervical cancer (He-La) using the dye exclusion method. We found that the percentage of anti-proliferation of the Tb3 compound was increased in a dose-dependent manner, where it showed 83% (K562), 72.3% (He-La), and 70.7% (A549) inhibition at higher concentration. These values were relatively higher compared ...


Perspectives On Finances And Mental Health Status Among Low-Income Los Angeles Latinas, Luisa R. Blanco, Jessica A. Baker, Julie A. Friedman, Karen T. Singh, Arleen F. Brown, Sierra D. Moon, Savanna L. Carson, Audree Hsu, Janet Pregler Dec 2020

Perspectives On Finances And Mental Health Status Among Low-Income Los Angeles Latinas, Luisa R. Blanco, Jessica A. Baker, Julie A. Friedman, Karen T. Singh, Arleen F. Brown, Sierra D. Moon, Savanna L. Carson, Audree Hsu, Janet Pregler

Journal of Financial Therapy

Abstract

Research has established a link between financial challenges and mental health outcomes. Understanding this linkage among low-income Latinas who face unique experiences and challenges in relation to managing their household finances is important. This study utilized a community-based participatory qualitative research method to explore perspectives on financial and mental health among Latinas residing in Los Angeles County. The implications of this study are applicable when conducting a culturally responsive financial therapy program. Three focus groups were conducted with mainly immigrant, Spanish-speaking, low-income Latinas (n = 37). The study found that though participants face financial stressors tied to managing finances, they ...


Enhancing Dissemination Of Evidence-Based Models For Stem Phd Career Development; A Stakeholder Workshop Report, Ryan Bixenmann, Barbara J. Natalizio, Yasmeen Hussain, Cynthia N. Fuhrmann Dec 2020

Enhancing Dissemination Of Evidence-Based Models For Stem Phd Career Development; A Stakeholder Workshop Report, Ryan Bixenmann, Barbara J. Natalizio, Yasmeen Hussain, Cynthia N. Fuhrmann

pd|hub Publications

Sustainability of the scientific enterprise requires being able to recruit, retain, and prepare ongoing generations of PhD-trained scientists ready to adapt with the evolving needs of the scientific workforce and society. This necessitates a broadened, trainee-centered view in doctoral and postdoctoral training—including a prominent focus on career planning, science across sectors, and development of professional skills. Although there is energy and movement to enhance graduate and postdoctoral training, actions remain disparate, leading to inefficiencies in implementation and lack of systemic change. In 2019, an emerging national initiative, Professional Development Hub (pd|hub), hosted a workshop to bring organizations and ...


Sources Of Nutrition Information In Recreational Ultra-Marathon Runners: A Mixed Methods Analysis, Sara E. Mahoney, Thomas R. Wójcicki, Andrew J. Carnes Dec 2020

Sources Of Nutrition Information In Recreational Ultra-Marathon Runners: A Mixed Methods Analysis, Sara E. Mahoney, Thomas R. Wójcicki, Andrew J. Carnes

Journal of Human Performance in Extreme Environments

Ultra-marathon events (i.e., .42.2-km) continue to grow in popularity; however, little is known regarding the sources of nutrition information which inform their beliefs and habits. The objective of this study was to characterize the acquisition of sport-specific nutrition information among ultra-endurance athletes using a mixed methods design. Qualitative data were collected through focus groups and analyzed using thematic analysis. Three primary higher order themes were identified: Optimal Diet for Ultra-Endurance Athletes, Common Sources of Information, and Barriers to Scientific Information. Then, a self-report inventory (Sources of Nutrition Information-SONI questionnaire) was developed to assess common sources of nutrition information ...


Community Engagement In Covid-19 Responses: Evidence From Qualitative Interface With Community Opinion Leaders In Enugu, Nigeria, Prince Agwu, Chinweoke Methodius Ugwu, Chidera Florence Eke Dec 2020

Community Engagement In Covid-19 Responses: Evidence From Qualitative Interface With Community Opinion Leaders In Enugu, Nigeria, Prince Agwu, Chinweoke Methodius Ugwu, Chidera Florence Eke

ASEAN Journal of Community Engagement

Successful stories of community engagement existed during the Ebola disease outbreak in Liberia, indicating that a combination of government and community efforts are needed in addressing pandemics or epidemics. However, for communities to rise to the challenge of containing and combatting the spread of any disease, they must be communicated most effectively and supported by the government. Therefore, our study investigates how applicable successful community engagement has been in the charge against the Coronavirus disease 2019 (COVID-19) in Nigeria. Through telephone interviews, we sourced data from 12 community opinion leaders in Enugu State, Nigeria. After conducting a thematic analysis of ...


The 21st Century Global Digital Economies Revolution And The Aftermath Of Covid-19 Pandemic: Some Anticipated Implication Changes For Developing Nations, Agyei Fosu Dec 2020

The 21st Century Global Digital Economies Revolution And The Aftermath Of Covid-19 Pandemic: Some Anticipated Implication Changes For Developing Nations, Agyei Fosu

ASEAN Journal of Community Engagement

The 21st century digital global economies era changed developmental approaches drastically to a point where most researchers, policy makers, and developers have asserted that to achieve economic development for developing nations; it is paramount for Information and Communications Technologies (ICTs) investments in all sectors contributing to their economy. The current COVID-19 pandemic and the various measures taken by governments such as lockdown, curfew, companies asking employees to work from home, and the use of e-learning by schools to curb the disease brings into perspective the assertion raised by various scholars about the need for developing nations to invest in ...


Music, Dhikr, And Deep Breathing Technique To Decrease Depression Level In Older Adults: Evidence-Based Practice In Depok City, Indonesia, Bahtiar Bahtiar, Junaiti Sahar, Wdiyatuti Widyatuti Dec 2020

Music, Dhikr, And Deep Breathing Technique To Decrease Depression Level In Older Adults: Evidence-Based Practice In Depok City, Indonesia, Bahtiar Bahtiar, Junaiti Sahar, Wdiyatuti Widyatuti

ASEAN Journal of Community Engagement

Depression is a mental health problem that affects the elderly. As meeting the spiritual needs of depressed older people is important, a spiritual approach nursing intervention must be applied to reduce the level of depression in this population. This study proposed an integrated spiritual nursing approach through music therapy, dhikr, and deep breathing to improve depression levels among the elderly living in Cisalak Pasar, Depok City, in 2019. The research method used was a case study of an evidence-based practice using the Geriatric Depression Scale. The study sample consisted of 106 elderly, who were recruited by purposive sampling. The average ...


Removal Of Mimosine From Leucaena Leucocephala (Lam.) De Wit Seeds To Increase Their Benefits As Nutraceuticals, Sri Wardatun, Yahdiana Harahap, Abdul Mun'im, Fadlina Chany Saputri Dr., Noorwati Sutandyo Dec 2020

Removal Of Mimosine From Leucaena Leucocephala (Lam.) De Wit Seeds To Increase Their Benefits As Nutraceuticals, Sri Wardatun, Yahdiana Harahap, Abdul Mun'im, Fadlina Chany Saputri Dr., Noorwati Sutandyo

Pharmaceutical Sciences and Research

The Leucaena leucocephala (Lam.) de Wit tree contains pharmacologically active compounds and can easily be found in abundant quantities. The utilization of this tree as a source of nutraceuticals would increase its value. The extraction yields show the number of compounds that have been extracted by solvent. However, Leucaena leucocephala (Lam.) de Wit seeds also contain mimosine, which can cause hair loss. The present study investigated the process of removing mimosine from the seeds. Three treatments were applied to these seeds: treatment without soaking, soaking with distilled water for 24 hours, and splitting the seeds in half and then soaking ...


Antioxidant And Antiaging Assays Of Ageratum Conyzoides (L.) Ethanolic Extract, Afifah B. Sutjiatmo, Novi Edriayani, Tira Endang Mulyasari, Faizal Hermanto, M. Fahrauk, Elin Y. Sukandar, Hanna Sari Widya Kusuma, Rizal Rizal, Wahyu Widowati Dec 2020

Antioxidant And Antiaging Assays Of Ageratum Conyzoides (L.) Ethanolic Extract, Afifah B. Sutjiatmo, Novi Edriayani, Tira Endang Mulyasari, Faizal Hermanto, M. Fahrauk, Elin Y. Sukandar, Hanna Sari Widya Kusuma, Rizal Rizal, Wahyu Widowati

Pharmaceutical Sciences and Research

The declining ability of tissues to repair or replace themselves and maintain their structure and normal function is called aging. Aging is caused by free radical that can induce the activation of elastase and collagenase. Ageratum conyzoides (L.) or known as Babadotan is a medicinal plant that has been reported to be a good source of antioxidants that also inhibit aging process. The purpose of this research is to evaluate the antioxidant and antiaging properties of Babadotan Ethanolic Extract (BEE). Franswoth method was used to determine the phytochemical assay of BEE. Measurement of 2,2-diphenyl 1-picrylhydrazyl (DPPH) scavenger was used ...


Evaluation Of Antipsychotic Activity Of Ethanolic Bark Extract Of Myrica Esculenta In Rats, Biswash Sapkota, Ankit Acharya, Bishal Dangi, Annegowda Hv Dec 2020

Evaluation Of Antipsychotic Activity Of Ethanolic Bark Extract Of Myrica Esculenta In Rats, Biswash Sapkota, Ankit Acharya, Bishal Dangi, Annegowda Hv

Pharmaceutical Sciences and Research

The antipsychotic properties of Myrica esculenta stem bark were evaluated. The stem bark was collected, shade dried, and pulverized. Extraction was carried out with 70% ethanol by occasional shaking. Preliminary phytochemical screening of the extract was investigated in this study. Antipsychotic activity was evaluated against apomorphine-induced stereotypy using cook’s pole climbing apparatus and haloperidol-induced catalepsy models. Bioamine determination of noradrenaline and dopamine was also performed. The extract contains phytochemicals, including glycosides, flavonoids, volatile oils, proteins, saponins, phenolics, and tannins. The result showed decreased apomorphine-induced stereotyped behavior. This study reported significant dose-dependent potentiation of haloperidol-induced catalepsy in rats and a ...


Potential Of Jamu In Nanotechnology Perspective As An Alternative Treatment For Covid-19, Dhadhang Wahyu Kurniawan, Azis Ikhsanudin Dec 2020

Potential Of Jamu In Nanotechnology Perspective As An Alternative Treatment For Covid-19, Dhadhang Wahyu Kurniawan, Azis Ikhsanudin

Pharmaceutical Sciences and Research

The world seems to be recovering at this time, especially because of the 2019 global coronavirus disease pandemic (COVID-19) caused by the Coronavirus 2 virus (SARS-CoV-2). This virus is similar to other β-coronaviruses through several steps to enter and bind angiotensin-converting enzyme 2 (ACE2) as the main receptor. This binding, particularly in the respiratory epithelium and alveoli of the lungs, affects harmony in human host cells. No specific vaccines and antivirals are available to date as drug investigations are still ongoing. However, many Indonesians consume herbal medicine, especially 'empon-empon' containing the Zingiberaceae family, to protect their health from COVID-19. So ...


Pathogenesis And Onset Of Tinnitus And Use Of Holistic And Traditional Audiological Approaches For Management, Christy Mahrt, Antony Joseph Dec 2020

Pathogenesis And Onset Of Tinnitus And Use Of Holistic And Traditional Audiological Approaches For Management, Christy Mahrt, Antony Joseph

AuD Capstone Projects - Communication Sciences and Disorders

Introduction: Tinnitus is the subjective sensation of noise perceived at the peripheral or central level. Occasionally, tinnitus perception may be severe enough to present debilitating effects on daily activities. The occurrence of tinnitus can be related to occupational or non-occupational hazardous noise exposure. Case Presentation: A 60-year-old male presented with bilateral tinnitus with an initial onset at age 21. The progression of his tinnitus has caused disruptions in sleeping patterns and concentration. His history included extensive occupational and non-occupational noise exposure. Discussion: Hearing conservation is an important aspect of facilitating tinnitus management for individuals who have noise-related tinnitus. Hearing aids ...