Prostate Cancer: Patient Education For Changing Guidelines, 2018 University of Vermont College of Medicine
Prostate Cancer: Patient Education For Changing Guidelines, Richard Mendez
Family Medicine Block Clerkship, Student Projects
In May 2012 United States Preventative Services Task Force (USPSTF) recommended against prostate cancer screening, Grade D, with no other recommendation for providers. Since prostate cancer continues to be among the most common cancer in the United States among men, patients were exposed to previous guidelines during routine visits and require updated educational materials for primary care visits.
Grand Rounds: Year End Roundup, 2017 Thomas Jefferson University
Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi
Jefferson Digital Commons News
Use your break to expand your knowledge by checking out the many Grand Rounds posted in the Jefferson Digital Commons. Topics range from nasal reconstruction to sexuality and aging. With hours of Grand Rounds to experience (see some samples below), your holiday will transform from boredom to excitement! Happy holidays from the Jefferson Digital Commons!
The Effects Of Perinatal Methamphetamine Use On Maternal And Child Outcomes: Implications For Education Among Bsn Nursing Students, 2017 University of Tennessee at Chattanooga
The Effects Of Perinatal Methamphetamine Use On Maternal And Child Outcomes: Implications For Education Among Bsn Nursing Students, Tina Nguyen
The implications of methamphetamine use are vast and prevalent in the U.S. This epidemic is also well recognized in Tennessee and in Hamilton County. The number of men and women that continue to use methamphetamine speaks to the importance of this issue. Among these individuals, pregnant women comprise a significant portion of female methamphetamine users across the United States. The potential complications that can arise for not only a mother but also her child due to maternal methamphetamine use pose a much more significant issue. The detrimental effects that a child can experience as a result of maternal methamphetamine ...
Primary Headache Disorders In The Adult General Population Of Pakistan - A Cross Sectional Nationwide Prevalence Survey., 2017 Headache Research Foundation of Pakistan, Karachi, Pakistan.
Primary Headache Disorders In The Adult General Population Of Pakistan - A Cross Sectional Nationwide Prevalence Survey., A. A. Herekar,, A. Ahmad, , U. L. Uqaili, Bilal Ahmed, J Effendi, S. Z. Alvi, , M. A. Shahab, U. Javed, A. D. Herekar, Rafiq Khanani, T. J. Steiner
Department of Medicine
Background: The large geographical gaps in our knowledge of the prevalence and burden of headache disorders include almost all of Eastern Mediterranean Region (EMR). We report a nationwide population-based study in Pakistan, an EMR country with the sixth largest population in the world, conducted as a project within the Global Campaign against Headache.
Methods: We surveyed six locations from the four provinces of Pakistan: Punjab, Sindh, Khyber Pakhtunkhwa and Baluchistan. We randomly selected and visited rural and urban households in each. One adult member (18–65 years) of each household, also randomly selected, was interviewed by a trained non-medical interviewer ...
The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, 2017 Dominican University of California
The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, Kimberly Kelsey
Senior Theses and Capstone Projects
Type 1 Diabetics have various ways of managing their diabetes that have been studied for their effectiveness. Pregnancy in the Type 1 Diabetic has been understudied. It is known that Diabetics in general have poorer pregnancy outcomes because of poor glycemic control. This coupled with the fact that the body needs 3-4 times more insulin as pregnancy comes to an end makes managing blood glucose levels challenging for diabetics (Lowdermilk, 2016, p. 689). For the Type 1 Diabetic, there are two main ways to control diabetes: multiple daily injections using at least two type of insulin and continuous subcutaneous insulin ...
Example Doctor Of Nursing Practice Project, 2017 Southern Illinois University Edwardsville
Example Doctor Of Nursing Practice Project, Steven W. Pryor Test
Doctor of Nursing Practice Projects
This is an example of a Doctor of Nursing Practice Project uploaded to SPARK.
This is where the abstract of the submission will appear, briefly summarizing the problem and research results in a few sentences.
What Are Endothelial Cells, 2017 Selected Works
What Are Endothelial Cells, Bennie Liu
Good Knowledge About Hypertension Is Linked To Better Control Of Hypertension; A Multicentre Cross Sectional Study In Karachi, Pakistan., Aysha Almas, Saniya Siraj Godil, Saima Lalani, Zahra Aziz Samani, Aamir Hameed
Department of Medicine
BackGround: According to the National Health survey only 3% of the population has controlled hypertension. This study was designed to elucidate the knowledge about hypertension in hypertensive patients at three tertiary care centers in Karachi. Secondly we sought to compare the knowledge of those with uncontrolled hypertension and controlled hypertension.
Methods: It was a cross-sectional study conducted at The Aga Khan University hospital (AKUH), Ziauddin Hospital (ZH) and Civil hospital, Karachi (CHK. All diagnosed Hypertensive patients (both inpatients and outpatients) coming to a tertiary care hospital in Pakistan aged > 18 years were included. Patients were categorized into 2 groups: controlled ...
Women’S Sexual Fantasies In Context: The Emotional Content Of Sexual Fantasies, Psychological And Interpersonal Distress, And Satisfaction In Romantic Relationships, 2017 The Graduate Center, City University of New York
Women’S Sexual Fantasies In Context: The Emotional Content Of Sexual Fantasies, Psychological And Interpersonal Distress, And Satisfaction In Romantic Relationships, Sarah Constantine
All Graduate Works by Year: Dissertations, Theses, and Capstone Projects
Background: Psychoanalytic thinkers propose that aspects of an individual’s sexual fantasies are related to her psychological and interpersonal functioning. The present study aims to elucidate the significance of sexual fantasies with respect to women’s emotional and interpersonal lives. The study evaluated a model, which hypothesized that internal representations of self and others (e.g. attachment security, maturity of object relations) along with psychological and interpersonal factors would predict both the emotional content (guilt, fear, affection) of written sexual fantasy narratives, and overall romantic satisfaction in heterosexual women. Methods: Five hundred and thirty four women completed self-report questionnaires online ...
The Effect Of Health Insurance Coverage And The Doctor-Patient Relationship On Health Care Utilization In High Poverty Neighborhoods, 2017 George Washington University
The Effect Of Health Insurance Coverage And The Doctor-Patient Relationship On Health Care Utilization In High Poverty Neighborhoods, Destini Smith, Alan Akira, Kenneth Hudson, Andrea Hudson, Marcellus Hudson, Marcus Mitchell, Errol Crook
School of Medicine and Health Sciences Student Works
African Americans have higher rates of mortality than whites who are the same age and sex. We hypothesize that in low socioeconomic status neighborhoods, having health insurance coverage and a regular health care provider increases the likelihood of receiving diagnostic tests for cardiovascular disease and diabetes. We use data from a random two-stage cluster sample of 230 adults living in high poverty census tracts to examine the effects of insurance coverage and having a regular doctor on the likelihood receiving diagnostic tests for high cholesterol, high blood sugar, and blood pressure. We find that health insurance coverage increases the odds ...
Resilience And Coping In The Adolescent And Young Adult With Type 1 Diabetes, 2017 Seton Hall University
Resilience And Coping In The Adolescent And Young Adult With Type 1 Diabetes, Debra L. Messinger
Seton Hall University Dissertations and Theses (ETDs)
There is a need to understand the roles coping strategies play in enhancing resilience in adolescents and young adults with type 1 diabetes between the ages of 18-30. The purpose of this study was to examine the relationships between and among positive, protective coping strategies (courageous coping), negative coping strategies (defensive coping), and resilience. The Resilience in Illness Model (Haase, Kinter, Monahan, & Robb, 2014) was the theoretical model which guided this research.
A convenience sample was recruited via diabetes organizations’ Facebook and Forum pages, a College Diabetes Network chapter meeting, and Juvenile Diabetes Research Foundations’ (JDRF) sponsored events. Data were ...
The Fight Against Breast Cancer: A Policy And Programmatic Approach, 2017 The University of San Francisco
The Fight Against Breast Cancer: A Policy And Programmatic Approach, Nandi Robinson
Master's Projects and Capstones
Breast cancer continues to remain a significant health issue for women. Previously thought to only occur among postmenopausal women, breast cancer has impacted women of different ages; and rates of breast cancer have various impacts among different ethnic groups. For women living in a toxic environment, many of them have become the new wave of breast cancer cases. Screening and detection have succeeded in decreasing mortality rates. However, more research is needed in finding an efficient method of treatment. In the effort to assist in the fight against breast cancer through a policy and programmatic angle, I am fulfilling ...
Outcomes Of An Integrated Approach To Speed And Strength Training With An Elite-Level Sprinter, 2017 East Tennessee State University
Outcomes Of An Integrated Approach To Speed And Strength Training With An Elite-Level Sprinter, Eric D. Magrum
Electronic Theses and Dissertations
The purpose of this study was to observe changes in sprint velocity, ground contact time, and peak force demonstrated by a competitive sprinter following an integrated approach to speed development and strength training. As part of an ongoing monitoring procedure the participant completed 20m sprint testing through an optical measurement system and isometric-strength testing before and after each phase of training. Sprint velocity, ground contact time and peak force were analysed using Tau-U, smallest worthwhile and percent change statistics. Results indicate sprinting velocity statistically improved while changes in peak force were practically significant and ground contact time remained trivial throughout ...
Added Sugar Consumption Among College Students, 2017 University of the Incarnate Word
Added Sugar Consumption Among College Students, Maram Murad
Theses & Dissertations
Added sugar consumption has been increasing in all age groups in the United States and worldwide, with the greatest increase in young adults. College-age years are a critical period in the young adult's life where many habits develop, including nutrition and food choices. An understanding of college-age students’ attitudes and behaviors toward added sugar consumption might help predict added sugar consumption within this population. This was a quantitative study of traditional-aged college students' added sugar consumption through a convenience sample at a private university in San Antonio, TX. A survey was administrated to undergraduate students at different classes. Subjects ...
Metabolic Regulation Of Cellular Signaling, 2017 University of Tennessee Health Science Center
Metabolic Regulation Of Cellular Signaling, Rashid John Darbandi
Theses and Dissertations (ETD)
Using the biochemically tractable Xenopus oocyte model system, we have previously characterized a novel metabolic regulation of cell death. We found that glucose-6-phosphate (G6P) via the pentose phosphate pathway leads to increased nicotinamide adenine dinucleotide phosphate (NADPH) levels, a subsequent increase in cytosolic acetyl-coenzyme A and activation of Ca2+/calmodulin-dependent protein kinase II (CaMKII). We recently identified coenzyme A (CoA), derived from the breakdown of acetyl-CoA, as the key metabolic signal that mediates a novel mechanism of calmodulindependent activation of CaMKII. CoA binds directly to the calmodulin (CaM) binding domain (CaMBD) of CaMKII resulting in its activation and downstream inhibitory ...
Data On The Effect Of Sex On The Size, Cellular Content, And Neuronal Density Of The Developing Brain In Mice Exposed To Isoflurane And Carbon Monoxid, L Wang, A Wang, W W. Supplee, K Koffler, Y Cheng, Z M.N. Quezado, R J. Levy
Anesthesiology and Critical Care Medicine Faculty Publications
The data presented here detail the changes in size, cellular content, and neuronal density of the developing brain over time with respect to sex in C57Bl/6 mice following neonatal exposure to isoflurane, carbon monoxide, or their combination. Specifically, brain weight- and brain volume-to-body weight ratios are presented, representative immunoblots of whole brain cell-specific protein content are depicted, and quantification of the number of neurons in the primary somatosensory cortex and CA3 region of the hippocampus are shown. Three discrete postnatal time points are represented: P7 (prior to exposure), P14 (one-week post exposure), and P42-56 (5–7 weeks post exposure ...
‘You Do Not Cross Them’: Hierarchy And Emotion In Doctors' Narratives Of Power Relations In Specialist Training, 2017 Royal College of Surgeons in Ireland
‘You Do Not Cross Them’: Hierarchy And Emotion In Doctors' Narratives Of Power Relations In Specialist Training, Sophie Crowe, Nicholas Clarke, Ruairi F. Brugha
Epidemiology and Public Health Medicine Articles
Studies of medical education often focus on experiences and socialisation processes among undergraduate students, with fewer examining emotionality among postgraduate trainees. This article explores the relationship between power and emotion, questioning how affective relations between senior and junior doctors are patterned on the hierarchical structure of medicine. The study employs qualitative methods of in-depth, face-to-face and telephone interviews with fifty doctors at initial and advanced stages of specialist postgraduate training in teaching hospitals across Ireland, conducted between May and July, 2015. The study found that respect for hierarchy, anger and fear, intimidation, and disillusion were key themes in participants' narratives ...
Iss-N1 Makes The First Fda-Approved Drug For Spinal Muscular Atrophy, 2017 Iowa State University
Iss-N1 Makes The First Fda-Approved Drug For Spinal Muscular Atrophy, Eric W. Ottesen
Spinal muscular atrophy (SMA) is one of the leading genetic diseases of children and infants. SMA is caused by deletions or mutations of Survival Motor Neuron 1 (SMN1) gene. SMN2, a nearly identical copy of SMN1, cannot compensate for the loss of SMN1 due to predominant skipping of exon 7. While various regulatory elements that modulate SMN2 exon 7 splicing have been proposed, intronic splicing silencer N1 (ISS-N1) has emerged as the most promising target thus far for antisense oligonucleotide-mediated splicing correction in SMA. Upon procuring exclusive license from the University of Massachussets Medical School in 2010, Ionis Pharmaceuticals (formerly ...
A Novel Human-Specific Splice Isoform Alters The Critical C-Terminus Of Survival Motor Neuron Protein, 2017 Iowa State University
A Novel Human-Specific Splice Isoform Alters The Critical C-Terminus Of Survival Motor Neuron Protein, Joonbae Seo, Natalia N. Singh, Eric W. Ottesen, Brian M. Lee, Ravindra N. Singh
Spinal muscular atrophy (SMA), a leading genetic disease of children and infants, is caused by mutations or deletions of Survival Motor Neuron 1 (SMN1) gene. SMN2, a nearly identical copy of SMN1, fails to compensate for the loss of SMN1 due to skipping of exon 7. SMN2predominantly produces SMNΔ7, an unstable protein. Here we report exon 6B, a novel exon, generated by exonization of an intronic Alu-like sequence of SMN. We validate the expression of exon 6B-containing transcripts SMN6B and SMN6BΔ7 in human tissues and cell lines. We confirm generation of SMN6B transcripts from both SMN1 and SMN2. We detect ...
Oxidative Stress Triggers Body-Wide Skipping Of Multiple Exons Of The Spinal Muscular Atrophy Gene, 2017 Iowa State University
Oxidative Stress Triggers Body-Wide Skipping Of Multiple Exons Of The Spinal Muscular Atrophy Gene, Joonbae Seo, Natalia N. Singh, Eric W. Ottesen, Senthilkumar Sivanesan, Maria Shishimorova, Ravindra N. Singh
Humans carry two nearly identical copies of Survival Motor Neuron gene: SMN1 and SMN2. Loss of SMN1 leads to spinal muscular atrophy (SMA), the most frequent genetic cause of infant mortality. While SMN2 cannot compensate for the loss of SMN1 due to predominant skipping of exon 7, correction of SMN2 exon 7 splicing holds the promise of a cure for SMA. Previously, we used cell-based models coupled with a multi-exon-skipping detection assay (MESDA) to demonstrate the vulnerability of SMN2 exons to aberrant splicing under the conditions of oxidative stress (OS). Here we employ a transgenic mouse model and MESDA to ...