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Current Understanding Of The Mechanism Of Action Of The Antiepileptic Drug Lacosamide, Michael A. Rogawski, Azita Tofighy, H Steve White, Alain Matagne, Christian Wolff 2015 University of California - Davis

Current Understanding Of The Mechanism Of Action Of The Antiepileptic Drug Lacosamide, Michael A. Rogawski, Azita Tofighy, H Steve White, Alain Matagne, Christian Wolff

Michael A. Rogawski

The antiepileptic drug lacosamide [(R)-2-acetamido-N-benzyl-3-methoxypropanamide], a chiral functionalized amino acid, was originally identified by virtue of activity in the mouse and rat maximal electroshock (MES) test. Attention was drawn to lacosamide because of its high oral potency and stereoselectivity. Lacosamide is also active in the 6 Hz seizure model but inactive against clonic seizures in rodents induced by subcutaneous pentylenetetrazol, bicuculline and picrotoxin. It is also ineffective in genetic models of absence epilepsy. At doses greater than those required to confer protection in the MES test, lacosamide inhibits behavioral and electrographic seizures in hippocampal kindled rats. It also effectively ...


Ngo's Bpa Report Intended To Frighten, Not Enlighten., Robert L. Brent Dr. 2015 duPont Hosp for Children

Ngo's Bpa Report Intended To Frighten, Not Enlighten., Robert L. Brent Dr.

The Selected Works of Robert Brent

None


Healthcare Information Systems: Opportunities And Challenges, Madison Ngafeeson 2015 Northern Michigan University

Healthcare Information Systems: Opportunities And Challenges, Madison Ngafeeson

Madison Ngafeeson

No abstract provided.


Immigrant & Refugee Family Wellness Through Yoga & Zumba, Elizabeth Crawford, Faith Swenson, Angela Serrani, Kathleen Cassidy, Brittany Roy 2015 University of New England

Immigrant & Refugee Family Wellness Through Yoga & Zumba, Elizabeth Crawford, Faith Swenson, Angela Serrani, Kathleen Cassidy, Brittany Roy

Immigrant and Refugee Family Wellness Engagement Through Yoga and Zumba

Research poster stemming from CEIPE mini-grant funded student project Immigrant And Refugee Family Wellness Engagement Through Yoga And Zumba. Students from multiple health professions collaborated to provide Yoga and Zumba classes at the Riverton Community Center. The project aimed to increase the participants’ ability to utilize stress reducing activities through a blend of student created heath education materials and yoga and zumba classes for refugee women and children.


The Relationships Among School Nurse To Student Ratios, Self-Efficacy For Type 1 Diabetes Management, And Glycemic Control In Adolescents, Lori Wilt 2015 Seton Hall University

The Relationships Among School Nurse To Student Ratios, Self-Efficacy For Type 1 Diabetes Management, And Glycemic Control In Adolescents, Lori Wilt

Seton Hall University Dissertations and Theses (ETDs)

Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases of childhood. Adolescents with T1DM experience decreased treatment adherence, poor glycemic control, and acute complications more frequently than adults. Self-efficacy is the belief that one can carry out specific behaviors in specific situations and is the major determinant of intention, and has been shown to influence diabetes self-management in the adolescent.

School nurses are in a unique position to influence self-efficacy for type 1 diabetes management in adolescents. Although previous research has shown that school nurses positively influence student health outcomes in a variety of ways, there ...


Exploring The Relationships Of Power, Attitudes Regarding Intermittent Fetal Monitoring, And Perceived Barriers To Research Utilization With A Labor And Delivery Nurse's Attitude Toward Patient Advocacy, Lisa Heelan 2015 Seton Hall University

Exploring The Relationships Of Power, Attitudes Regarding Intermittent Fetal Monitoring, And Perceived Barriers To Research Utilization With A Labor And Delivery Nurse's Attitude Toward Patient Advocacy, Lisa Heelan

Seton Hall University Dissertations and Theses (ETDs)

A problem identified in nursing practice was the routine use of continuous fetal monitoring (CEFM) with low risk laboring women. CEFM is associated with worsened outcomes for the low risk laboring woman with no benefit to the newborn. In addition, this routine practice does not allow most laboring women the right to make an informed choice regarding treatment options. Nursing includes the role of patient advocacy. There was a need to better understand what is associated with a labor and delivery nurse’s attitude toward patient advocacy.

This descriptive correlational research design examined the relationships of power as knowing participation ...


Exploring The Relationship Between Moral Distress And Coping In Emergency Nursing, Kathleen Zavotsky 2015 Seton Hall University

Exploring The Relationship Between Moral Distress And Coping In Emergency Nursing, Kathleen Zavotsky

Seton Hall University Dissertations and Theses (ETDs)

Background: Emergency Department (ED) nurses practice in environments that are highly charged and unpredictable in nature and can precipitate conflict between the necessary prescribed actions and the individual’s sense of what is morally the right thing to do. As a consequence of multiple moral dilemmas ED staff nurses are at risk for experiencing distress and how they cope with these challenges may impact their practice.

Objectives: Is to examine moral distress in ED nurses and its relationship to coping in that specialty group.

Methods: Using survey methods approach. One hundred ninety eight ED nurses completed a moral distress, coping ...


The Relationships Among Perceived Stress, Birth Satisfaction, And Breastfeeding Self-Efficacy In Early Postpartum Women, Katherine Hinic 2015 Seton Hall University

The Relationships Among Perceived Stress, Birth Satisfaction, And Breastfeeding Self-Efficacy In Early Postpartum Women, Katherine Hinic

Seton Hall University Dissertations and Theses (ETDs)

This descriptive correlational study examined the relationships among perceived stress, birth satisfaction, and breastfeeding self-efficacy in women in the early postpartum period. The study, guided by self-efficacy and stress and coping theories, aimed to identify factors related to breastfeeding self-efficacy, an important psychological variable in sustained breastfeeding. The sample (N =107) was comprised of primarily well-educated, higher income, non-Hispanic White (69.8%) women recruited from a single New Jersey hospital in the first four days postpartum. The sample was comprised of nearly equal numbers of primiparous and multiparous women, all of whom expressed an intention to breastfeed, with an overall ...


Spiritual Perspective, Mindfulness, And Spiritual Care Practices Of Hospice And Palliative Care Nurses, Patricia Ricci-Allegra 2015 Seton Hall University

Spiritual Perspective, Mindfulness, And Spiritual Care Practices Of Hospice And Palliative Care Nurses, Patricia Ricci-Allegra

Seton Hall University Dissertations and Theses (ETDs)

Spiritual care is an ethical obligation of the nursing profession and an essential component of palliative care, but is often misunderstood. Lack of conceptual clarity is problematic, for each nurse will provide spiritual care based on his or her understanding of what this care should include.

Regardless of how a nurse defines spiritual care, an important element of spiritual care is what nurses bring of themselves to the patient encounter. Findings from several studies have shown a positive relationship between a nurse’s spiritual perspective and spiritual care practices. Spiritual perspective has increased as a result of participating in programs ...


Exploration Of The Relationships Between And Among Role Strain, Faculty Stress, And Organizational Support For Clinical Nurse Faculty Faced With A Decision To Assign A Failing Grade, Jeannie Couper 2015 Seton Hall University

Exploration Of The Relationships Between And Among Role Strain, Faculty Stress, And Organizational Support For Clinical Nurse Faculty Faced With A Decision To Assign A Failing Grade, Jeannie Couper

Seton Hall University Dissertations and Theses (ETDs)

Despite a stressful process, Clinical Nurse Faculty (CNF) are ultimately responsible for assigning a grade indicating that a student successfully met clinical course outcomes and standards of safe practice required to progress (Amicucci, 2012). The purpose of this descriptive correlational study was to explore the relationships between perceived role strain (PRS), perceived faculty stress (PFS), and perceived organizational support (POS) for CNF who faced the decision to assign a failing grade to a student in a clinical practicum. A national sample of 390 predominantly full-time, female, experienced CNF teaching in undergraduate and graduate nursing programs completed the online survey consisting ...


An Investigation Of The Relationships Between And Among Power, Trust And Job Satisfaction Of Nurse Managers In Acute Care Hospitals Using Rogers Science Of Unitary Human Beings, Maureen A. Schneider 2015 Seton Hall University

An Investigation Of The Relationships Between And Among Power, Trust And Job Satisfaction Of Nurse Managers In Acute Care Hospitals Using Rogers Science Of Unitary Human Beings, Maureen A. Schneider

Seton Hall University Dissertations and Theses (ETDs)

Background: Defined as control and freedom, power is often characterized as hierarchical. Power-as-freedom exists as a unitary manifestation of the whole and is acausal. Thus a worldview that emphasizes mutual process rather than a causal (control) view supports a culture of trust in the healthcare environment that generates a committed and a thriving work force. When nurse leaders support a climate of trust, managers develop a sense of commitment to the organization which may lead to job satisfaction. However, there is a lack of empirical evidence supporting the relationship between power, trust and job satisfaction among nurse managers.

Purpose: The ...


Factors Contributing To Registered Nurse Job Satisfaction In The Nursing Home, Michael Shipley 2015 Seton Hall University

Factors Contributing To Registered Nurse Job Satisfaction In The Nursing Home, Michael Shipley

Seton Hall University Dissertations and Theses (ETDs)

Over the next several years the aging population will increase the number of patients suffering from chronic illness. A sicker aging population, coupled with changes in healthcare reimbursement will require nursing homes to admit sicker patients for shorter lengths of stays. To meet the needs of the increased number of chronic patients and those patients with higher acuities, nursing homes will require more skilled, registered nurses. Registered nurses (RNs) are the linchpin to providing high-quality care in the healthcare environment and especially in nursing homes.

Understanding the factors of RN job satisfaction in the nursing home is important in increasing ...


Acute Effects Of Self-Myofascial Release And Static Stretching On Shoulder Range Of Motion And Performance In Overhead Athletes With Glenohumeral Internal Rotation Deficit, Ryan R. Fairall 2015 Seton Hall University

Acute Effects Of Self-Myofascial Release And Static Stretching On Shoulder Range Of Motion And Performance In Overhead Athletes With Glenohumeral Internal Rotation Deficit, Ryan R. Fairall

Seton Hall University Dissertations and Theses (ETDs)

Purpose: The purpose of this study was to examine the acute effects of a) self-myofascial release (SMR), b) static stretching (SS), and c) the combination of self-myofascial release and static stretching (SMR+SS) on glenohumeral internal rotation range of motion and markers of shoulder performance (i.e. glenohumeral external rotation isometric strength, motor unit recruitment, and throwing velocity) in male softball players with glenohumeral internal rotation deficit (GIRD).

Methods: The sample consisted of 12 male amateur softball players (age: 36.92 ±11.17 years; height: 177.42 ±6.30cm; mass: 87.58 ±18.39kg) who exhibited ≥20° less internal rotation ...


The Effects Of Walking On The Alter-G® Treadmill On Fat Oxidation In Overweight/Obese Males, Toni LaSala, Toni LaSala 2015 Seton Hall University

The Effects Of Walking On The Alter-G® Treadmill On Fat Oxidation In Overweight/Obese Males, Toni Lasala, Toni Lasala

Seton Hall University Dissertations and Theses (ETDs)

Purpose: To determine if a reduction of body weight from 100% to 75% while walking on a lower body positive pressure treadmill (LBPP) affects peak oxygen consumption (V̇O2peak), fat oxidation (FO), peak fat oxidation (PFO), respiratory exchange ratio (RER), heart rate (HR) and rate of perceived exertion (RPE) in overweight and or obese men. Methods: Fourteen, overweight and obese men (mean age 23.2 ± 2.4 years, BMI 36.5 ± 3.8 kg/m2 and Body Fat % 38.6 ± 7.0%) were randomly assigned to walking on the LBPP treadmill at 100% and 75% of their body ...


Segmentation Of Pulmonary Nodules In Computed Tomography Using A Regression Neural Network Approach And Its Application To The Lung Image Database Consortium And Image Database Resource Initiative Dataset, Temesguen Messay, Russell C. Hardie, Timothy R. Tuinstra 2015 University of Dayton

Segmentation Of Pulmonary Nodules In Computed Tomography Using A Regression Neural Network Approach And Its Application To The Lung Image Database Consortium And Image Database Resource Initiative Dataset, Temesguen Messay, Russell C. Hardie, Timothy R. Tuinstra

Engineering and Computer Science Faculty Publications

We present new pulmonary nodule segmentation algorithms for computed tomography (CT). These include a fully-automated (FA) system, a semi-automated (SA) system, and a hybrid system. Like most traditional systems, the new FA system requires only a single user-supplied cue point. On the other hand, the SA system represents a new algorithm class requiring 8 user-supplied control points. This does increase the burden on the user, but we show that the resulting system is highly robust and can handle a variety of challenging cases. The proposed hybrid system starts with the FA system. If improved segmentation results are needed, the SA ...


Leadership Practices Among Undergraduate Nursing, Melissa M. Bryant 2015 The University of Southern Mississippi

Leadership Practices Among Undergraduate Nursing, Melissa M. Bryant

Dissertations

The purpose of this study is to identify leadership practices of nursing instructors in the southern U.S.; and to determine if instructor leadership practices differ from the ‘norm’ leadership practices reported by the LPI instrument (Posner 2008), or from the practices observed by their matched students (observer version). Further, the purpose is to determine the relationship between instructors self-reported leadership practices (self-version) and student observed practices based on institution type, and instructor education level. The consisted of a group of instructors and students that were primarily Caucasian and female. The demographics for the instructors and students were similar to ...


Participants' Perceptions Of Factors In Preventing Falls, Jaclyn Fok 2015 Dominican University of California

Participants' Perceptions Of Factors In Preventing Falls, Jaclyn Fok

Scholarly and Creative Works Conference

Falls pose a serious threat to older adults, often resulting in physical, emotional, and financial consequences. The use of multifactorial fall prevention programs has provided community- dwelling older adults with strategies to decrease the risk of falling. Outcomes for these programs are measured in terms of such factors as fear of falling, balance and self-efficacy. One outcome of fall prevention programs that is less well understood is what the older adults themselves perceive as most beneficial. For this program evaluation project, five women participated in semi-structured interviews to understand which aspects of a multifactorial fall prevention program they found to ...


Interprofessional Collaboration Between Occupational Therapists And Registered Nurses In Acute Care Settings: An Exploratory Study, Vincent P. O'Brien, Bethany Loy, Kelly Nguyen, Holly Micheff 2015 Dominican University of California

Interprofessional Collaboration Between Occupational Therapists And Registered Nurses In Acute Care Settings: An Exploratory Study, Vincent P. O'Brien, Bethany Loy, Kelly Nguyen, Holly Micheff

Scholarly and Creative Works Conference

Background. Collaboration between occupational therapists and nurses is key to a positive prognosis for their patients. Currently, there is a gap in the research on professional relationships between occupational therapists and registered nurses in acute care settings. Purpose. To examine interprofessional collaboration between registered nurses and occupational therapy in an acute care setting. Methods. A phenomenological, qualitative design with use of semi-structured interviews was used. Interviewees were four occupational therapists and four registered nurses who currently work in acute care settings in Northern California and were recruited through a snowball, convenience and purposive sampling. Themes and subthemes that emerged from ...


Nurse’S Perceptions Of Best Practices To Assess Pediatric Patients And Educate Their Families Experiencing Delayed Effects Of Cancer Therapy: “Chemo Brain:” A Pilot Study, Jennifer A. Tapping 2015 Dominican University of California

Nurse’S Perceptions Of Best Practices To Assess Pediatric Patients And Educate Their Families Experiencing Delayed Effects Of Cancer Therapy: “Chemo Brain:” A Pilot Study, Jennifer A. Tapping

Scholarly and Creative Works Conference

With more advanced and more aggressive chemotherapy cancer treatment leading to higher survival rates, complications with quality of life are becoming more prominent. Of these complications, delayed cognitive processing, commonly known as “chemo brain,” is becoming a topic of interest. Cognitive changes are some of the most common as well as most challenging complications associated with central nervous system (CNS) directed treatment, such as intrathecal chemotherapy, for acute lymphoblastic leukemia (ALL) and brain tumors. The term “chemo brain” is often used to describe self-reported or observed cognitive processing delays in patients who receive chemotherapy as a form of cancer treatment ...


Acl Injuries In Female Athletes, Leslie A. Mesa 2015 Dominican University of California

Acl Injuries In Female Athletes, Leslie A. Mesa

Scholarly and Creative Works Conference

The Anterior Cruciate Ligament has been studied in many different ways and become injured more with the increase in sports participation by both male and female athletes. “ACL injuries are 9x more common in female athletes than male athletes and over 1.4 million women have been suffered from the ACL rupture which is twice the rate of the previous decade” (Hewett, 2010). ACL injuries are known to occur more in females than males because of differences in anatomy, knee alignment, muscle strength, and conditioning. Since female athletes are more prone to injury, it is important to incorporate neuromuscular training ...


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