Shifting The Load: Improving Bioscience Performance In Undergraduate Nurses Through Student Focused Learning, Angela Owens, Tracey Moroney

Angela Owens

Nicotine-Induced Effects On Nicotinic Acetylcholine Receptors (Nachrs), Ca2+ And Brain-Derived Neurotrophic Factor (Bdnf) In Stc-1 Cells, Jie Qian, Shobha K. Mummalaneni, Reem M. Alkahtan, Sunila Mahavadi, Karnam S. Murthy, John R. Grider, Vijay Lyall

Physiology and Biophysics Publications

In addition to the T2R bitter taste receptors, neuronal nicotinic acetylcholine receptors (nAChRs) have recently been shown to be involved in the bitter taste transduction of nicotine, acetylcholine and ethanol. However, at present it is not clear if nAChRs are expressed in enteroendocrine cells other than beta cells of the pancreas and enterochromaffin cells, and if they play a role in the synthesis and release of neurohumoral peptides. Accordingly, we investigated the expression and functional role of nAChRs in enteroendocrine STC-1 cells. Our studies using RT-PCR, qRT-PCR, immunohistochemical and Western blotting techniques demonstrate that STC-1 cells express several α and ...

A Trial Of Wound Irrigation In The Initial Management Of Open Fracture Wounds, Mohit Bhandari, Kyle J. Jeray, Brad A. Petrisor, P. J. Devereaux, Diane Heels-Ansdell, Emil H. Schemitsch, Jeff Anglen, Gregory J. Della Rocca, Clifford Jones, Hans Kreder, Susan Liew, Paula Mckay, Steven Papp, Parag Sancheti, Sheila Sprague, Trevor B. Stone, Xin Sun, Stephanie L. Tanner, Paul Tornetta, Ted Tufescu, Stephen Walter, Gordon H. Guyatt

Bone and Joint Institute

Copyright © 2015 Massachusetts Medical Society. BACKGROUND The management of open fractures requires wound irrigation and dridement to remove contaminants, but the effectiveness of various pressures and solutions for irrigation remains controversial. We investigated the effects of castile soap versus normal saline irrigation delivered by means of high, low, or very low irrigation pressure. METHODS In this study with a 2-by-3 factorial design, conducted at 41 clinical centers, we randomly assigned patients who had an open fracture of an extremity to undergo irrigation with one of three irrigation pressures (high pressure [>20 psi], low pressure [5 to 10 psi], or very ...

Principles Of Multidisciplinary Management, Richard S. Pieters, James Liebmann

Cancer Concepts: A Guidebook for the Non-Oncologist

This chapter in Cancer Concepts: a Guidebook for the Non-Oncologist describes the principles of multi-disciplinary management, meaning multi-specialty physician management of malignancies. Tumor Boards are the model for multi-disciplinary management. They may be site specific or include the entire spectrum of malignancy. At Tumor Boards, staging workup and treatment recommendations are made collectively, and then the treatments are delivered by the respective modality specialists and their individual teams. Improved clinical decision making leading to superior survival for patients with some diseases and better quality of life has been documented with multi-disciplinary management. Just like curative patients, palliative patients require multi-disciplinary ...

Impact Of Parental Stress On Asthma Management Behaviors And Health Outcomes: A Longitudinal Analysis Of Inner City School-Aged Children, Amanda Constance Green

Graduate Doctoral Dissertations

Background. Asthma is a prevalent chronic condition with excess disease burden in school-aged, minority children from low income inner-city communities. Conceptualized within a nursing and socio-ecological framework, the purpose of this secondary analysis of a prospective study of inner-city school-aged children with asthma (School Inner-City Asthma Study [SICAS]) was to examine associations between characteristics of children and parents, parents stress, parent asthma management behaviors (AMB) and child asthma outcomes, including emergency (ED) visits for asthma, missed school and asthma control.

Methods. The sample included 351 school-aged children (7.9 years old, SD= 1.9 years; 53.0% male; 95.7 ...

Rapamycin Rescues Vascular, Metabolic And Learning Deficits In Apolipoprotein E4 Transgenic Mice With Pre-Symptomatic Alzheimer’S Disease, Ai-Ling Lin, Jordan B. Jahrling, Wei Zhang, Nicholas Derosa, Vikas Bakshi, Peter Romero, Veronica Galvan, Arlan Richardson

Sanders-Brown Center on Aging Faculty Publications

Apolipoprotein E ɛ4 allele is a common susceptibility gene for late-onset Alzheimer's disease. Brain vascular and metabolic deficits can occur in cognitively normal apolipoprotein E ɛ4 carriers decades before the onset of Alzheimer's disease. The goal of this study was to determine whether early intervention using rapamycin could restore neurovascular and neurometabolic functions, and thus impede pathological progression of Alzheimer's disease-like symptoms in pre-symptomatic Apolipoprotein E ɛ4 transgenic mice. Using in vivo, multimodal neuroimaging, we found that apolipoprotein E ɛ4 mice treated with rapamycin had restored cerebral blood flow, blood–brain barrier integrity ...

Suppression Of F1 Male-Specific Lethality In Caenorhabditis Hybrids By Cbr-Him-8, Vaishnavi Ragavapuram, Emily Elaine King, Scott Everet Baird

Biological Sciences Faculty Publications

Haldane's Rule and Darwin's Corollary to Haldane's Rule are the observations that heterogametic F1 hybrids frequently are less fit than their homogametic siblings and that asymmetric results often are obtained from reciprocal hybrid crosses. In Caenorhabditis, Haldane's Rule and Darwin's Corollary have been observed in several hybrid crosses, including crosses of Caenorhabditis briggsae and Caenorhabditis nigoni. Fertile F1 females are obtained from reciprocal crosses. However, F1 males obtained from C. nigoni mothers are sterile and F1 males obtained from C. briggsae die during embryogenesis. We have identified cbr-him-8 as a recessive maternal-effect suppressor of F1 ...

Cystic Fibrosis Lung Infections: Polymicrobial, Complex, And Hard To Treat, Laura M. Filkins, George A. O’Toole

Dartmouth Scholarship

No abstract provided.

Beyond The Ring: Vegan Fighter, Bianca Silva

Capstones

Omowale Adewale, an amateur MMA fighter and boxer, spends his time outside the ring as director of Grassroots Artists MovEment (G.A.ME), an organization in the Bronx dedicated to provide resources to low-income residents like healthcare, access to healthy foods via means of gardening and youth incarceration prevention programs. He has been the director of G.A.ME since 2001 and routinely visits classrooms where he provides lectures on how to eat healthy foods-even incorporating vegan foods and implement after school physical programs like boxing where he occasionally serves as a trainer.

Byrd, Maya Dangerfield

Capstones

In April 2015, William Byrd Wilkins or ‘Byrd’, 50, a theatre and television actor, was diagnosed with pancreatic cancer. In August, his friends crowd-funded an all expense paid trip to New York for Byrd who wasundergoing chemotherapy in his rural hometown of Louisburg, North Carolina. Originally described as ‘an opportunity to reconnect’ the trip soon developed into a ‘living funeral’ as Byrd and his friends grappled with Byrd’s terminal prognosis. As he visited his favorite New York haunts and met with friends, Byrd wrestled with the decision to end his chemotherapy upon his return home.

She's Having A Baby And Cancer, Ashley Lewis

Capstones

In October 2011, Megan Harris, a 38-year-old high school teacher from Atlanta, Georgia, found out she was pregnant with a new addition to her happy family of three. But she didn’t know until three months later that she’d be planning a funeral rather than a nursery.

The Fight For Zadroga, Naeisha Rose

Capstones

The attack on the World Trade Center cost many first responders and volunteers, like Ken George, a retired highway crewmember who was part of the search and rescue, to lose their health. Ken had needs a respirator for his restricted airway disease, he is o n 33 medications and five years ago he had a heart attack. Bi- =weekly or monthly, he visits a doctor for his PTSD, his heart, his lungs and general healthcare. After seeing the devastating conditions that the responders like Ken worked in, Congresswoman C arolyn Maloney (D-12) worked tirelessly with many politicians, both Democrats and ...

Special Muscles, Annamaria C. Scaccia

Capstones

Special Muscles is a documentary that explores living with Duchenne muscular dystrophy, a fatal degenerative disease that weakens the muscles at an aggressive rate. The film will give an uncensored look at how one family copes with inevitability of the disease and their journey chasing a promising experimental cure.

Special Muscles follows 7-year-old Pietro Scarso and his family as they face the challenges, complications and promise of treating Pietro’s progressive muscle disorder. The film travels from New York to Los Angeles to Philadelphia to document the Scarso family’s race against time as Pietro undergoes a 96-week clinical trial ...

The War At Home, Joseph A. Altobelli Mr.

Capstones

This site was made to show how the cuts to and politics behind the Veterans Affairs Hospital in New York affects the veterans it is set up to care for.

Neurologists Look At Causes Of Baffling Brain Condition, Maggie Freleng

Capstones

It can be hard getting help for someone with mental illness, but almost impossible when that person doesn't think they are sick. At at least half of people with schizophrenia, for example, insist that the voices they hear are real. People who do not know they are ill often refuse therapy and medication -- and their symptoms can spiral out of control. Doctors call this lack of awareness anosognosia. Neurologists are trying to discover what causes this baffling condition--and how to treat it.

When Birth Control Hurts You: An Essure Investigation, Mia A. Garchitorena

Capstones

Thousands of women report having suffered from injuries and malfunctions related to Essure permanent birth control, including chronic pain, heavy bleeding, migration, or perforation. Many of these women also claim that Essure has caused nickel allergies, hair loss, bloating, rashes, unintended pregnancies, and death. What was promised to be an easy solution has become a life-altering problem.

As patient complaints have increased, experts have gone back and studied the science behind the approval of the Essure device. Their findings are startling: There were flaws with the studies that supported the Food and Drug Administration’s approval of the device, the ...

Battle Echoes Never Fade: Soldiers' Trauma At The End Of Life, John E. Eller

Capstones

Soldiers suffer moral injuries when wartime experiences go against their own moral compass, such as killing innocent civilians or mutilating the bodies of enemies. Many soldiers bury the shame and guilt leftover from battle for years or decades, but these memories can surface unbidden as veterans near death.

How N.Y.’S Biggest For-Profit Nursing Home Group Flourishes Despite A Record Of Patient Harm, Jennifer Lehman

Capstones

How N.Y.'s Biggest For-Profit Nursing Home Group Flourishes Despite a Record of Patient Harm

The state’s “character-and-competence” reviews are supposed to weed out operators with histories of violations and fines— but regulators don’t always act on the full story.

Research News. Publications, 2015. Volume 2, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period July 1 through December 15, 2015

Effects Of Melatonin On Heartbeat And Possible Identification Of A Melatonin Receptor In Drosophila Melanogaster, Tricia L. Vankirk

Electronic Theses and Dissertations

Chapter 1 of this manuscript is a literature review that serves as an introduction to the entire dissertation. Chapter 2 examines the effects of the melatonin injection on heart rate and rhythmicity in Drosophila melanogaster Canton-S (wild-type) pupae and pupae bearing a variety of heart mutations. Chapter 3 investigates further the possible mechanisms of melatonin’s ability to increase heart rhythmicity without significantly affecting heart rate. A melatonin antagonist, luzindole; a high-affinity melatonin agonist, 2-iodomelatonin and RNAi techniques are used to identify a possible melatonin receptor in Drosophila melanogaster.

An appendix contains a previously published manuscript detailing experiments performed at ...

Using Detection Dogs And Rspf Models To Assess Habitat Suitability For Bears In Greater Yellowstone, Jon P. Beckmann, Lisette P. Waits, Aimee Hurt, Alice Whitelaw, Scott Bergen

Western North American Naturalist

In the northern U.S. Rockies, including the Greater Yellowstone Ecosystem (GYE), connectivity is a concern because large carnivores have difficulties dispersing successfully between protected areas. One area of high conservation value because of its importance for connecting the GYE to wilderness areas of central Idaho is the Centennial Mountains and surrounding valleys (2500 km2) along the Idaho–Montana border just west of Yellowstone National Park. The current expansion of grizzly bears (Ursus arctos) and other large carnivore populations outside protected areas of Yellowstone National Park and Grand Teton National Park has placed a greater emphasis on potential linkage zones ...

Black-Tailed And White-Tailed Jackrabbits In The American West: History, Ecology, Ecological Significance, And Survey Methods, Matthew T. Simes, Kathleen M. Longshore, Kenneth E. Nussear, Greg L. Beatty, David E. Brown, Todd C. Esque

Western North American Naturalist

Across the western United States, Leporidae are the most important prey item in the diet of Golden Eagles (Aquila chrysaetos). Leporids inhabiting the western United States include black-tailed (Lepus californicus) and white-tailed jackrabbits (Lepus townsendii) and various species of cottontail rabbit (Sylvilagus spp.). Jackrabbits (Lepus spp.) are particularly important components of the ecological and economic landscape of western North America because their abundance influences the reproductive success and population trends of predators such as coyotes (Canis latrans), bobcats (Lynx rufus), and a number of raptor species. Here, we review literature pertaining to black-tailed and white-tailed jackrabbits comprising over 170 published ...

Life History, Burrowing Behavior, And Distribution Of Neohermes Filicornis (Megaloptera: Corydalidae), A Long-Lived Aquatic Insect In Intermittent Streams, Matthew R. Cover, Jeong Ho Seo, Vincent H. Resh

Western North American Naturalist

Several species of fishflies (Megaloptera: Corydalidae: Chauliodinae) have been reported from intermittent streams in western North America, but the life histories and distributions of these species are poorly understood. We studied the life history ofNeohermes filicornis (Banks 1903) for 2 years in Donner Creek (Contra Costa County, California), a small intermittent stream that flows for 5–7 months per year. Neohermes filicornis had a 3–4-year life span and larval growth was asynchronous. Analysis of gut contents showed that larvae were generalist predators of aquatic insect larvae including Diptera, Ephemeroptera, and Plecoptera. Final instars dug pupal chambers in the ...

First Record Of Jaguar (Panthera Onca) From The State Of Hidalgo, México, Melany Aguilar-López, Josefina Ramos-Frías, Alberto E. Rojas-Martínez, Cristian Cornejo-Latorre

Western North American Naturalist

We documented the first record of jaguar (Panthera onca) in the state of Hidalgo, México. With this record, the gap in the distribution of jaguar between San Luis Potosí and northwestern Puebla is reduced. In July 2013, we found 2 tracks on a trail in a pine-oak forest, and in October, we photographed a jaguar in an oak forest. Both sites are located within the Parque Nacional Los Mármoles in Sierra Gorda of Hidalgo. These records represent the first evidence of the presence of jaguar in Hidalgo, which is among the few states where all 6 species of felids that ...

A Comparison Of Sign Searches, Live-Trapping, And Camera-Trapping For Detection Of American Badgers (Taxidea Taxus) In The Chihuahuan Desert, Robert L. Harrison

Western North American Naturalist

In communities where they occur, American badgers (Taxidea taxus) play important ecological, economic, and conservation roles. Central to understanding of badger ecology and management are estimates of badger population status. However, few studies have compared methods of detecting badgers for population surveys. I compared searches for burrows and diggings, live-trapping, and the use of automatic cameras at scent lures, bait stations, and anthropogenic permanent and temporary wildlife water sources in the Chihuahuan Desert of southern New Mexico. Searches for confirmed badger burrows and diggings yielded 0.14–0.88 detections per kilometer of transect. Badgers were trapped in 1.6 ...

Phenetic Analyses And Revised Classification Of The Ptelea Trifoliata Complex (Rutaceae), Erin Skornia, Muxi Yang, Wendy L. Applequist

Western North American Naturalist

The current classification of Ptelea divides the widespread and highly variable Ptelea trifoliata L. into 5 subspecies and 11 varieties, while additionally terming many specimens “intermediate.” Although there are visually observable differences among regional variants, principal component analyses of quantitative characters failed to separate subspecies or to even incompletely separate most varieties within subspecies. Some recognized subgroups are also not well distinguished by discontinuous qualitative characters. Where multiple varieties appear to be part of a single continuum of variation or are extremely similar, it is suggested that a reduction in the number of infraspecific taxa would improve the utility of ...

Production And Nutrient Content Of Two Shrub Species Related To Fire In Central Idaho, James M. Peek

Western North American Naturalist

Nutrient content and weight of current year’s growth of Cercocarpus ledifolius Nuttall and Physocarpus malvaceus (Greene) Kuntze in central Idaho were obtained during early July in the years 1987–2007. The purpose of this work was to determine whether there was significant variation between years and whether mean monthly temperatures and total monthly precipitation could predict the variation. A wildfire in August 2000 causedP. malvaceus to vigorously resprout. Significant differences between years occurred for all nutrients for both species. October temperatures best predicted weight of current year’s growth in C. ledifolius, whereas prediction equations for nutrients involved ...

Maternity Roost Selection By Fringed Myotis In Colorado, Mark A. Hayes, Rick A. Adams

Western North American Naturalist

Fringed myotis (Myotis thysanodes) is a bat species of conservation concern in western North America that may be impacted by increased recreational activity near roost sites, changes in water resource availability caused by increased urban and agricultural water use, and anthropogenic climate change. Our purpose was to describe and model maternity roost use by fringed myotis in Colorado. We compared differences between roosts occupied by maternal fringed myotis and randomly selected potential roosting locations that were not known to be occupied by this species during the maternity period. We evaluated the strength of evidence for competing hypotheses on 2 scales ...

Front Matter, Vol. 75 No. 4

Western North American Naturalist

No abstract provided.

Facing A Changing World: Thermal Physiology Of American Pikas (Ochotona Princeps), Hans W. Otto, James A. Wilson, Erik A. Beever

Western North American Naturalist

American pikas (Ochotona princeps) are of concern with respect to warming montane temperatures; however, little information exists regarding their physiological ability to adapt to warming temperatures. Previous studies have shown that pikas have high metabolism and low thermal conductance, which allow survival during cold winters. It has been hypothesized that these characteristics may be detrimental, given the recent warming trends observed in montane ecosystems. We examined resting metabolic rate, surface activity, and den and ambient temperatures (Ta) of pikas in late summer (August 2011 and 2012) at 2 locations in the Rocky Mountains. Resting metabolic rate was calculated to be ...