Medicine and Health Sciences Commons^™

Effectiveness Of Emotionally Focused Therapy (Eft) With Chinese Couple Clients: From The Chinese Eft Therapists' Cultural Lens, Yifan Wang

Doctoral Dissertations and Projects

The purpose of this phenomenological study is to understand the Chinese EFT (Emotionally Focused Therapy) therapists’ experiences of working with Chinese couples in EFT sessions, as well as to discover how the cultural factors play a role in the effectiveness of EFT use with Chinese couples. This study was conducted by finding out 10 EFT-oriented therapists and analyzing via online interviews their experiences of working with Chinese couples. The theories guiding this study are based on Emotionally Focused Therapy (EFT). One of the founding therapists of this approach is Dr. Sue Johnson. EFT is heavily influenced by attachment theory, which …

Exploring The Relationship Between Staffing And Long-Term Care Worker Mental Health, Matthew R. Trombley

Doctoral Dissertations and Projects

This research delves into the relationship between staffing levels during a crisis in the healthcare workforce and the mental well-being of long-term care workers, with a specific focus on variables such as burnout, compassion fatigue, and compassion satisfaction. With increasing workforce shortages, the attention to providing quality care during this tumultuous period has become increasingly urgent. There has been scarce empirical research that has explicitly sought to comprehend the connection between staffing levels and the mental health of long-term care professionals. This study was designed as a non-experimental, quantitative correlational investigation, aiming to understand the intricate dynamics between patient-to-staff ratios …

Burnout Triggers In The Novice Registered Nurse, Sharon K. Nguyen

Doctoral Dissertations and Projects

Nurse burnout has been strongly associated with decreased patient satisfaction and reduced retention rates in the novice registered nurse. This phenomenon is exacerbating the already rising global nursing shortage. A strong correlation is established between novice registered nurses who endure repeated or multiple triggers, such as unsafe staffing ratios, inadequate preceptorship, and ineffective leadership to those who succumb to burnout. Burnout is a significant problem in the United States, impacting how healthcare is perceived by the public. In 2019 there were more than six million nurses, making up the largest segment of the healthcare population and directly affecting the safety …

Cd36 Regulates Factor Viii Secretion From Liver Endothelial Cells, Paula Reventun, Pablo Toledano-Sanz, Nunzio Alcharani, Maria Viskadourou, Alanna C Morrison, Maria Sabater-Lleal, Alisa S Wolberg, Paul S De Vries, Nicholas L Smith, William O Osburn, Marios Arvanitis, Charles J Lowenstein

Journal Articles

No abstract provided.

Cd36 Regulates Factor Viii Secretion From Liver Endothelial Cells, Paula Reventun, Pablo Toledano-Sanz, Nunzio Alcharani, Maria Viskadourou, Alanna C Morrison, Maria Sabater-Lleal, Alisa S Wolberg, Paul S De Vries, Nicholas L Smith, William O Osburn, Marios Arvanitis, Charles J Lowenstein

Journal Articles

No abstract provided.

Using Interprofessional Collaboration To Bridge Athletic Training And Strength And Condition Programs In High School Settings To Reduce Injuries, Craig Hermans

Doctoral Dissertations and Projects

The purpose of this practicum is to identify the differences between between the athletic training professional and the strength and conditioning professional in a school which may cause barriers in using interprofessional collaboration. Currently, the rate of reinjury in a student-athlete population is quite high due, in part, to the different focuses between athletic trainers and that of strength and conditioning coaches. This practicum prepares a compiled review of the literature of research as well as independent research evaluating the student/athletes’ recovery from injury in relation to reinjury. The findings from the research serve a purpose to establish a deeper …

Medication Errors In Hospitals, Isata Jalloh

Doctoral Dissertations and Projects

In hospitals, the issue of medication errors poses a serious problem, often leading to substantial health complications and, in some cases, even deaths among hospitalized as well as discharged patients. This health challenge not only imposes a substantial financial burden on patients, insurance providers, and Federal/State governments but also contributes to elevated healthcare expenses, hindering the effective allocation of resources to address other healthcare issues. Understanding the triggers of medication errors in hospitals is critical in solving this problem. The purpose of this integrative review is to determine the causes/triggers of medication errors in hospitals. This review will highlight the …

Multiple Pathways For Glucose Phosphate Transport And Utilization Support Growth Of Cryptosporidium Parvum, Rui Xu, Wandy L Beatty, Valentin Greigert, William H Witola, L David Sibley

2020-Current year OA Pubs

Cryptosporidium parvum is an obligate intracellular parasite with a highly reduced mitochondrion that lacks the tricarboxylic acid cycle and the ability to generate ATP, making the parasite reliant on glycolysis. Genetic ablation experiments demonstrated that neither of the two putative glucose transporters CpGT1 and CpGT2 were essential for growth. Surprisingly, hexokinase was also dispensable for parasite growth while the downstream enzyme aldolase was required, suggesting the parasite has an alternative way of obtaining phosphorylated hexose. Complementation studies in E. coli support a role for direct transport of glucose-6-phosphate from the host cell by the parasite transporters CpGT1 and CpGT2, thus …

Clinical Outcomes Of Older And Younger Patients Treated With Loncastuximab Tesirine In The Lotis-2 Clinical Trial, Mehdi Hamadani, Brad Kahl, Et Al.

2020-Current year OA Pubs

No abstract provided.

Exploring The Role Of Physical Activity Influencing Emotional Regulation And Mental Health In Adolescents, Alejandro G. Martinez, Lindsay Gietzen, Valerie F. Mcdaniel

Pacific Journal of Health

This research paper explores the intricate relationship between physical activity, emotional regulation, and mental health in adolescents through an in-depth content analysis grounded in catharsis theory and the transactional theory of stress and coping. It underscores physical activity as the best practice for adolescents to manage emotions and mental health, identifying key themes that highlight its role in enhancing emotional regulation skills and reducing anger, anxiety, and depression. The catharsis theory suggests physical activity releases negative emotions, while the transactional theory explores how adolescents perceive and respond to stressors. Emphasizing the positive impact of physical activity on emotional regulation and …

Stevens-Johnson Syndrome From Combined Allopurinol And Angiotensin-Converting Enzyme Inhibitors: A Narrative Review, Isabella M. Fabian, Kirsten Maddox, Cameron Robicheaux, Rahib K. Islam, Ahmed Anwar, Bradley Dorius, Christopher L. Robinson, Adam M. Kaye, Giustino Varrassi, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye

School of Pharmacy Faculty Articles

Stevens-Johnson syndrome (SJS) is a severe and potentially debilitating skin reaction frequently related to medication use. Allopurinol and angiotensin-converting enzyme (ACE) inhibitors are commonly prescribed medications for prevalent health conditions worldwide, and their interaction associated with SJS warrants further investigation. A comprehensive literature search was performed to investigate cases as studies related to SJS occurring in patients with concomitant use of allopurinol and ACE inhibitors. We identified case reports and studies detailing hypersensitivity reactions, including SJS, attributed to a combination of allopurinol and ACE inhibitors. Despite the drug-drug interactions or lack thereof seen in patient populations, there is no definitive …

Refugee Health In Philadelphia, Marc Altshuler, Md

Academic Commons Workshops and Presentations

No abstract provided.

Stevens-Johnson Syndrome From Combined Allopurinol And Angiotensin-Converting Enzyme Inhibitors: A Narrative Review, Isabella M. Fabian, Kirsten Maddox, Cameron Robicheaux, Rahib K. Islam, Ahmed Anwar, Bradley Dorius, Christopher L. Robinson, Adam M. Kaye, Giustino Varrassi, Shahab Ahmadzadeh, Sahar Shekoohi, Alan D. Kaye

School of Medicine Faculty Publications

Stevens-Johnson syndrome (SJS) is a severe and potentially debilitating skin reaction frequently related to medication use. Allopurinol and angiotensin-converting enzyme (ACE) inhibitors are commonly prescribed medications for prevalent health conditions worldwide, and their interaction associated with SJS warrants further investigation. A comprehensive literature search was performed to investigate cases as studies related to SJS occurring in patients with concomitant use of allopurinol and ACE inhibitors. We identified case reports and studies detailing hypersensitivity reactions, including SJS, attributed to a combination of allopurinol and ACE inhibitors. Despite the drug-drug interactions or lack thereof seen in patient populations, there is no definitive …

Gene-Sgan: Discovering Disease Subtypes With Imaging And Genetic Signatures Via Multi-View Weakly-Supervised Deep Clustering, Zhijian Yang, John C Morris, Pamela Lamontagne, Daniel S Marcus, Tammie L S Benzinger, Et Al.

2020-Current year OA Pubs

Disease heterogeneity has been a critical challenge for precision diagnosis and treatment, especially in neurologic and neuropsychiatric diseases. Many diseases can display multiple distinct brain phenotypes across individuals, potentially reflecting disease subtypes that can be captured using MRI and machine learning methods. However, biological interpretability and treatment relevance are limited if the derived subtypes are not associated with genetic drivers or susceptibility factors. Herein, we describe Gene-SGAN - a multi-view, weakly-supervised deep clustering method - which dissects disease heterogeneity by jointly considering phenotypic and genetic data, thereby conferring genetic correlations to the disease subtypes and associated endophenotypic signatures. We first …

A Conceptual Analysis Of Sbirt Implementation Alongside The Continuum Of Prep Awareness: Domains Of Fit And Feasibility., Lesley M. Harris, Kerr C. Jelani, Blake D. Skidmore, Smita Ghare, Andrea Reyes-Vega, Vania Remenik-Zarauz, Harideep Samanapally, Rana U. Anwar, Rishikesh Rijal, Kendall Bryant, Martin T. Hall, Shirish Barve

Faculty Scholarship

Screening, Brief Intervention, and Referral to Treatment (SBIRT) is a supplementary intervention that can be incorporated into the Pre-Exposure Prophylaxis (PrEP) Care Continuum, complementing initiatives and endeavors focused on Human Immunodeficiency Virus (HIV) prevention in clinical care and community-based work. Referencing the Transtheoretical Model of Change and the PrEP Awareness Continuum, this conceptual analysis highlights how SBIRT amplifies ongoing HIV prevention initiatives and presents a distinct chance to address identified gaps. SBIRT's mechanisms show promise of fit and feasibility through (a) implementing universal Screening (S), (b) administering a Brief Intervention (BI) grounded in motivational interviewing aimed at assisting individuals in …

Investigating Clot-Flow Interactions By Integrating Intravital Imaging With In Silico Modeling For Analysis Of Flow, Transport, And Hemodynamic Forces, Chayut Teeraratkul, Maurizio Tomaiuolo, Timothy Stalker, Debanjan Mukherjee

Cardeza Foundation for Hematologic Research

As a blood clot forms, grows, deforms, and embolizes following a vascular injury, local clot-flow interactions lead to a highly dynamic flow environment. The local flow influences transport of biochemical species relevant for clotting, and determines the forces on the clot that in turn lead to clot deformation and embolization. Despite this central role, quantitative characterization of this dynamic clot-flow interaction and flow environment in the clot neighborhood remains a major challenge. Here, we propose an approach that integrates dynamic intravital imaging with computer geometric modeling and computational flow and transport modeling to develop a unified in silico framework to …

From Static Web To Metaverse: Reinventing Medical Education In The Post-Pandemic Era, Kadriye O. Lewis, Vitaliy Popov, Syeda Sadia Fatima

Department of Biological & Biomedical Sciences

The World Wide Web and the advancement of computer technology in the 1960s and 1990s respectively set the ground for a substantial and simultaneous change in many facets of our life, including medicine, health care, and medical education. The traditional didactic approach has shifted towards more dynamic and interactive methods, leveraging technologies such as simulation tools, virtual reality, and online platforms. At the forefront is the remarkable evolution that has revolutionized how medical knowledge is accessed, disseminated, and integrated into pedagogical practices. The COVID-19 pandemic also led to rapid and large-scale adoption of e-learning and digital resources in medical education …

Course Portfolio For Biochemistry 1: Structure And Metabolism (Bioc431), Didier Mena

UNL Faculty Course Portfolios

This benchmark portfolio encapsulates a comprehensive exploration aimed at enhancing the educational landscape of the BIOC431 course, a part of the general biochemistry course series (431 and 432). These courses are designed to offer a general introduction to the structure and function of cells in the body, along with their chemical reactions. Specifically, BIOC431 focuses on the structure, function, and metabolism of proteins, lipids, carbohydrates, and other major metabolic pathways. The three primary objectives addressed in this portfolio were the reevaluation of learning objectives, reassessment of assessment methods, and documentation of effective classroom strategies. Through background design, the learning objectives …

“Everything Seems To Be The Right Eye In Our Family”: Intergenerational Family Living With Facial Eye Disfigurement: An Interpretative Phenomenological Analysis, Zali M. O'Dea Ms, Jane Southcott

The Qualitative Report

This paper presents the lived experience of an intergenerational family, spanning three generations living with Facial Eye Disfigurement (FED). Living with vision loss and FED is estimated to affect nearly 8 billion people worldwide. Inadequate attention is paid to the impact of Living with FED (LwFED) on the lives of individuals. This research offers a deep dive into the lived experiences of one family LwFED. This family comprises a grandfather (deceased), son, wife, and child, all of whom have lived or live with FED. In this Interpretive Phenomenological Analysis (IPA) study three interviewees are deemed the experts. Data were collected …

County-Level Trends And Potential Disparities In The Suicide Rates In Virginia, 2020 – 2022, Sharon A. Olowoyo, Oluwatosin M. Oduneye, Glodi B. Bokanya, Ayooluwa G. Olowoyo, Coralie E. Mugenga, Yuhan Yan, Robyn L. Anderson

Montview Journal of Research & Scholarship

Abstract

Objectives

This study aims to investigate the influence of social determinants of health (SDH) on suicide patterns in the state of Virginia.

Methods

A secondary statistical analysis was conducted using publicly accessible data from the County Health Rankings & Roadmaps database for Virginia. Data from 2020 to 2022 were analyzed, focusing on age-adjusted suicide rates and SDH factors, including % rural, mental health provider rate, median household income, high school completion, and unemployment rates. Multiple regression analysis and visualizations were employed for data interpretation.

Results

The analysis revealed that SDH factors significantly predicted suicide rates across the study period. …

Characteristics Of Patients Undergoing Electrophysiologic Procedures In A Tertiary Hospital In Saudi Arabia, Abdullah A. Aljammaz, Meshaal K. Alghanim, Ibraheem Altamimi, Mohammed A. Alshwieer, Albaraa Sabbagh, Abdulrahman S. Alsayed, Faisal G. Al-Zahrani, Mohammad F. Almanjomi, Sameer Qutub, Wael A. Alqarawi

Journal of the Saudi Heart Association

Introduction: The electrophysiology field has progressed rapidly over the last 2 decades. No study has examined the characteristics of patients and types of electrophysiology procedures performed in the Kingdom of Saudi Arabia. This is important given our distinctly different demographic composition and health system. As such, we sought to describe the characteristics of consecutive patients presenting for electrophysiology procedures in our tertiary care hospital.

Methods: Data was collected from the electrophysiology database at King Khalid University Hospital for procedures performed between April 2016 and November 2022. Patients’ characteristics were retrieved from the electronic medical record. Procedures were categorized into supraventricular …

Epidemiological, Bacteriological, And Evolutive Features Of Children Hospitalized For Infective Endocarditis In A Tertiary Tunisian Pediatric Department, Houda Ajmi, Rahma Herch, Hela Elghali, Dalel Ben Sliman, Mohamed Ben Rejeb, Sameh Mabrouk, Fadoua Majdoub, Salsabil Nouir, Lamia Tilouche, Abdelhalim Trabelsi, Saoussan Abroug, Jalel Chemli

Journal of the Saudi Heart Association

Background: Infective endocarditis is a rare condition in childhood, and there is limited data on this disease in Tunisia.

Objective: This study aims to analyze the epidemiological profile, bacteriological data, and prognosis of infective endocarditis in children admitted to the pediatric department of a University Hospital in Tunisia.

Methods: We conducted a comparative cross-sectional study in the pediatric department of Sahloul Teaching Hospital in Sousse, a tertiary referral hospital in Tunisia. The study included all children aged ≤ 18 years with infective endocarditis admitted to the tertiary referral center for pediatrics in Sahloul University Hospital from January 1994 to December …

Percutaneous Vertebroplasty: A Minimally Invasive Procedure For The Management Of Dorsolumbar Compression Fractures, Yasser Bahgat Elsisi, Ahmed Gabry El Nagar, Osama Saber Shereef

Menoufia Medical Journal

Objectives: to study percutaneous vertebroplasty in the management of compression fractures of thoracolumbar spine regarding its advantages, drawbacks, complications, and outcome. Background: The lifetime risk of a vertebral body compression fracture is 16% for women and 5% for men. Vertebroplasty require the clinician to be experienced in spinal anatomy, fluoroscopic imaging, and the use of these methods to perform interventional procedures. Methods: a retrospective study over a 3-year period, cluster sample of patients. 30 patients with stable compression fractures from January 2018 to January 2021 who were surgically treated by percutaneous vertebroplasty at the Neurosurgery Department, Faculty of Medicine, Menoufia …

Evaluation Of Myocardial Function In Neonatal Sepsis Using Tissue Doppler Imaging, Fahima Mohamed Hassan, Dina Abdel Razek Midan, Afaf Hassan Sayed Ahmed El Roba, Basim Abdelfattah Ali Elgazzar

Menoufia Medical Journal

Objectives: To assess the ventricular function in neonatal sepsis using tissue Doppler imaging (TDI). Background: A leading cause of newborn morbidity and mortality is neonatal sepsis. Cardiac dysfunction is a significant side effect of severe sepsis. Methods: This study is a prospective case-control study that was conducted from August 2020 to March 2021with 50 neonates having culture-proven sepsis (cases), recruited from Neonatal Intensive Care Unit (NICU) of Menoufia University Hospital together with another 50 age and sex-matched sepsis-free neonates (control). Patients were subjected to history taking, clinical examination, routine investigations (complete blood count (CBC), quantitative C-reactive protein, ALT, AST, creatinine, …

Serum Neuron-Specific Enolase And S100Β Protein As Serum Biomarkers Of Brain Injury To Classify Outcome After Pediatric Sepsis, Fady M Elgendy, Fahima M Hasaan, Hassan S Bader, Mohamed S Rizk, Neveen M Fawzy

Menoufia Medical Journal

Objectives: To evaluate serum neuron-specific enolase and S100β protein as biomarkers for the detection of brain injury in pediatric sepsis and mortality. Background Septic-associated encephalopathy (SAE) is a common manifestation of sepsis, which associated with higher rates of mortality.

Methods: This case-control study was conducted on 45 septic cases admitted to the Pediatric Intensive Care Unit (PICU), Pediatric Department, Menoufia University Hospitals and 45 apparently healthy children. NSE and S100β protein serum biomarkers were measured by ELISA kits in the second day of sepsis diagnosis and patients were followed for a month.

Results: There was a highly significant increase in …

Lupus Kidney Disease Spectrum And Characteristics Among Egyptian Adults And Children With Sle, Emad Mohammad Elshebiny, Simon Alphonse Botros, Mohamed Shokry Elharoun, Zeinab Abdelaziz Kasemy, Samar Tharwat Radwan, Enas Sobhy Zahran

Menoufia Medical Journal

Objective: This research aimed to study the renal involvement among adults and children with systemic lupus erythematosus. Background: In addition to the glomerular affection "lupus Nephritis"(LN), there are other forms of lupus kidney disease; tubulointerstitial nephritis (TIN); vascular disease; and drug-induced renal disease can be found in Systemic Lupus Erythematosus (SLE) patients. Patient and Methods: A cross-sectional hospital-based study was conducted on 100 SLE patients (74 adults and 26 children) with presumed renal involvement. Patients were assessed clinically and by laboratory tests for renal involvement and renal biopsy findings were recorded to classify renal affection stage and type. Results: Clinically …

Low Inguinal Microsurgical Varicocele Ligation Versus Conventional Inguinal Approach: Prospective Comparison Of Reproductive And Functional Outcomes, Ahmed Gamal El Din, Ahmed Moustafa Barsim, Mohamed Marzouk Abdallah, Eid Abdel Rasol El-Sherif

Menoufia Medical Journal

Objectives: to evaluate the effectiveness and complications rates after microsurgical varicocele ligation in comparison to conventional inguinal approach. Methods: This study was a clinical randomized trial done in Menoufia Urology Department including eighty-three patients with varicocele from December 2018 to December 2020. Patients with clinical varicoceles and affected semen parameters were randomized to either conventional or microsurgical inguinal varicocelectomy. Intraoperative and post-operative complications were documented including hydrocele formation, varicocele recurrence, and testicular atrophy. Semen analysis was repeated after 3 months from date of surgery and compared to the pre-operative one. Results: Semen parameters improved significantly after varicocelectomy in both groups …

Urodynamic And Ultrasonic Findings After Anterior Vaginal Wall Prolapse Repair In Stress Urinary Incontinence, Mahy N. Egiz, Mohammed A. Elsayed, Mohammed A. Elshazly, Alaa M. Gomaa, Mohammed W. Abdelaziz

Menoufia Medical Journal

Objectives: To detect changes in ultrasound and urodynamic study in patients with stress urinary incontinence. Background: Assessment of urinary bladder neck mobility as part of assessment of SUI can be done by ultrasonography. It can be done through assessing urethral angles and bladder neck descent distance has for objective documentation of anatomical and functional parameters of the pelvic floor before and after surgery. Methods: a prospective longitudinal study was done on three groups of patients, first group included 16 cases of normal healthy individuals as control, the second group included 16 cases with anterior vaginal wall prolapse complicated by SUI, …

Major Incidental Findings In Ct Chest During Covid 19 Outbreak, Mohamed Basiony Alghannam, Amira Shawky Abdelhakim Eissa, Rehab Mohammed Habib

Menoufia Medical Journal

Objective: The objective of this study was to evaluate the role of multidetector computed tomography (CT) in the detection of major incidental findings of COVID 19 patients and to detect their clinical importance. Background: The outbreak of COVID-19 has caused concerns globally. On 30 January WHO has declared it as a global health emergency. Chest CT has a potential role in the diagnosis of coronavirus disease 2019 (COVID-19). Parenchymal and extra parenchymal incidental findings were detected and defined as any finding in the report not related to the purpose of the scan. Incidental findings on chest CT may represent highly …

Immunohistochemical Expression Of Heparanase Ii In Non-Melanoma Skin Cancer, Ola A. Elbakry, Mohamed A. Shoeib, Menna A. Abdelmonsif, Marwa M. Dawoud

Menoufia Medical Journal

Background: Heparan sulphate is present in the extracellular matrix of the skin. Heparanase is implicated in cellular invasion related to inflammation, cancer metastasis and angiogenesis. Heparanase II may inhibit heparanase activity by competing for the HS substrate. Heparanase II regulates selected genes that promote normal differentiation, endoplasmic reticulum stress, tumor fibrosis, and apoptosis, together resulting in tumor suppression. Aim: to investigate the involvement of heapranase II in non-melanoma skin cancer (NMSC) pathogenesis. Materials and Method: This study was carried out on a total number of 60 subjects, 30 cases with NMSC [15 cases with BCC and 15 cases with SCC] …