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Articles 1 - 30 of 125704

Full-Text Articles in Medicine and Health Sciences

Mechanical Properties Of Canine Patella-Ligament-Tibia Segment., Jeffery Biskup, Andy Freeman, W Camisa, J Innes, Michael Conzemius Jan 2104

Mechanical Properties Of Canine Patella-Ligament-Tibia Segment., Jeffery Biskup, Andy Freeman, W Camisa, J Innes, Michael Conzemius

Jeffery Biskup, DVM, DACVS

OBJECTIVE: To test the ex vivo mechanical properties of canine patella-ligament-tibia (PLT) segment and establish the relationship between donor size and PLT dimensions to the mechanical properties of PLT grafts.STUDY DESIGN: Ex vivo mechanical testing study. SAMPLE POPULATION: Canine PLT segments (n = 21 dogs; 42 PLT). METHODS:Morphometric measurements of PLT segments were taken from computed tomography (CT) images and compared with results obtained using calipers. PLT were tested to failure at a rate of 100% length/s. Mechanical properties and failure mode were recorded. RESULTS: PLT width and thickness (P < .001 for both) measured by calipers were significantly lower than those taken from CT images. Thirty-five (83%) specimens failed by avulsion fracture from the patella, 1 failed mid-ligament, and 6 failed by tibial fracture. Dog weight and PLT length had the strongest Pearson's r value when correlated with load at failure (r = 0.73, 0.81, respectively). CONCLUSION:Dog weight and PLT length were the best predictors of load at failure. PLT failure load of dogs weighing >25 kg were similar to those reported for ...


Prostate Cancer: Patient Education For Changing Guidelines, Richard Mendez Jan 2018

Prostate Cancer: Patient Education For Changing Guidelines, Richard Mendez

Family Medicine Block Clerkship, Student Projects

In May 2012 United States Preventative Services Task Force (USPSTF) recommended against prostate cancer screening, Grade D, with no other recommendation for providers. Since prostate cancer continues to be among the most common cancer in the United States among men, patients were exposed to previous guidelines during routine visits and require updated educational materials for primary care visits.


Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi Dec 2017

Grand Rounds: Year End Roundup, Daniel G. Kipnis, Msi

Jefferson Digital Commons News

Use your break to expand your knowledge by checking out the many Grand Rounds posted in the Jefferson Digital Commons. Topics range from nasal reconstruction to sexuality and aging. With hours of Grand Rounds to experience (see some samples below), your holiday will transform from boredom to excitement! Happy holidays from the Jefferson Digital Commons!


The Effects Of Perinatal Methamphetamine Use On Maternal And Child Outcomes: Implications For Education Among Bsn Nursing Students, Tina Nguyen Dec 2017

The Effects Of Perinatal Methamphetamine Use On Maternal And Child Outcomes: Implications For Education Among Bsn Nursing Students, Tina Nguyen

Honors Theses

The implications of methamphetamine use are vast and prevalent in the U.S. This epidemic is also well recognized in Tennessee and in Hamilton County. The number of men and women that continue to use methamphetamine speaks to the importance of this issue. Among these individuals, pregnant women comprise a significant portion of female methamphetamine users across the United States. The potential complications that can arise for not only a mother but also her child due to maternal methamphetamine use pose a much more significant issue. The detrimental effects that a child can experience as a result of maternal methamphetamine ...


Primary Headache Disorders In The Adult General Population Of Pakistan - A Cross Sectional Nationwide Prevalence Survey., A. A. Herekar,, A. Ahmad, , U. L. Uqaili, Bilal Ahmed, J Effendi, S. Z. Alvi, , M. A. Shahab, U. Javed, A. D. Herekar, Rafiq Khanani, T. J. Steiner Dec 2017

Primary Headache Disorders In The Adult General Population Of Pakistan - A Cross Sectional Nationwide Prevalence Survey., A. A. Herekar,, A. Ahmad, , U. L. Uqaili, Bilal Ahmed, J Effendi, S. Z. Alvi, , M. A. Shahab, U. Javed, A. D. Herekar, Rafiq Khanani, T. J. Steiner

Department of Medicine

Background: The large geographical gaps in our knowledge of the prevalence and burden of headache disorders include almost all of Eastern Mediterranean Region (EMR). We report a nationwide population-based study in Pakistan, an EMR country with the sixth largest population in the world, conducted as a project within the Global Campaign against Headache.

Methods: We surveyed six locations from the four provinces of Pakistan: Punjab, Sindh, Khyber Pakhtunkhwa and Baluchistan. We randomly selected and visited rural and urban households in each. One adult member (18–65 years) of each household, also randomly selected, was interviewed by a trained non-medical interviewer ...


The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, Kimberly Kelsey Dec 2017

The Effects Of Continuous Insulin Pump Therapy On Glycemic Control In Pregnant Type 1 Diabetics, Kimberly Kelsey

Senior Theses and Capstone Projects

Type 1 Diabetics have various ways of managing their diabetes that have been studied for their effectiveness. Pregnancy in the Type 1 Diabetic has been understudied. It is known that Diabetics in general have poorer pregnancy outcomes because of poor glycemic control. This coupled with the fact that the body needs 3-4 times more insulin as pregnancy comes to an end makes managing blood glucose levels challenging for diabetics (Lowdermilk, 2016, p. 689). For the Type 1 Diabetic, there are two main ways to control diabetes: multiple daily injections using at least two type of insulin and continuous subcutaneous insulin ...


Example Doctor Of Nursing Practice Project, Steven W. Pryor Test Nov 2017

Example Doctor Of Nursing Practice Project, Steven W. Pryor Test

Doctor of Nursing Practice Projects

This is an example of a Doctor of Nursing Practice Project uploaded to SPARK.

This is where the abstract of the submission will appear, briefly summarizing the problem and research results in a few sentences.


What Are Endothelial Cells, Bennie Liu Oct 2017

What Are Endothelial Cells, Bennie Liu

Bennie Liu


Endothelial cells form the inner lining of a blood vessel and provides an anticoagulant barrier between the vessel wall and blood. Endothelial cells also generate an antithrombotic surface that facilitates transit of plasma and cellular constituents throughout the vasculature. As a selective permeability barrier, the endothelial cell is a unique multifunctional cell with critical basal and inducible metabolic and synthetic functions. The endothelial cell reacts with physical and chemical stimuli within the circulation and regulates hemostasis, vasomotor tone, and immune and inflammatory responses. In addition, the endothelial cell is pivotal in angiogenesis and vasculogenesis.


Good Knowledge About Hypertension Is Linked To Better Control Of Hypertension; A Multicentre Cross Sectional Study In Karachi, Pakistan., Aysha Almas, Saniya Siraj Godil, Saima Lalani, Zahra Aziz Samani, Aamir Hameed Oct 2017

Good Knowledge About Hypertension Is Linked To Better Control Of Hypertension; A Multicentre Cross Sectional Study In Karachi, Pakistan., Aysha Almas, Saniya Siraj Godil, Saima Lalani, Zahra Aziz Samani, Aamir Hameed

Department of Medicine

BackGround: According to the National Health survey only 3% of the population has controlled hypertension. This study was designed to elucidate the knowledge about hypertension in hypertensive patients at three tertiary care centers in Karachi. Secondly we sought to compare the knowledge of those with uncontrolled hypertension and controlled hypertension.

Methods: It was a cross-sectional study conducted at The Aga Khan University hospital (AKUH), Ziauddin Hospital (ZH) and Civil hospital, Karachi (CHK. All diagnosed Hypertensive patients (both inpatients and outpatients) coming to a tertiary care hospital in Pakistan aged > 18 years were included. Patients were categorized into 2 groups: controlled ...


Women’S Sexual Fantasies In Context: The Emotional Content Of Sexual Fantasies, Psychological And Interpersonal Distress, And Satisfaction In Romantic Relationships, Sarah Constantine Sep 2017

Women’S Sexual Fantasies In Context: The Emotional Content Of Sexual Fantasies, Psychological And Interpersonal Distress, And Satisfaction In Romantic Relationships, Sarah Constantine

All Graduate Works by Year: Dissertations, Theses, and Capstone Projects

Background: Psychoanalytic thinkers propose that aspects of an individual’s sexual fantasies are related to her psychological and interpersonal functioning. The present study aims to elucidate the significance of sexual fantasies with respect to women’s emotional and interpersonal lives. The study evaluated a model, which hypothesized that internal representations of self and others (e.g. attachment security, maturity of object relations) along with psychological and interpersonal factors would predict both the emotional content (guilt, fear, affection) of written sexual fantasy narratives, and overall romantic satisfaction in heterosexual women. Methods: Five hundred and thirty four women completed self-report questionnaires online ...


The Effect Of Health Insurance Coverage And The Doctor-Patient Relationship On Health Care Utilization In High Poverty Neighborhoods, Destini Smith, Alan Akira, Kenneth Hudson, Andrea Hudson, Marcellus Hudson, Marcus Mitchell, Errol Crook Sep 2017

The Effect Of Health Insurance Coverage And The Doctor-Patient Relationship On Health Care Utilization In High Poverty Neighborhoods, Destini Smith, Alan Akira, Kenneth Hudson, Andrea Hudson, Marcellus Hudson, Marcus Mitchell, Errol Crook

School of Medicine and Health Sciences Student Works

African Americans have higher rates of mortality than whites who are the same age and sex. We hypothesize that in low socioeconomic status neighborhoods, having health insurance coverage and a regular health care provider increases the likelihood of receiving diagnostic tests for cardiovascular disease and diabetes. We use data from a random two-stage cluster sample of 230 adults living in high poverty census tracts to examine the effects of insurance coverage and having a regular doctor on the likelihood receiving diagnostic tests for high cholesterol, high blood sugar, and blood pressure. We find that health insurance coverage increases the odds ...


Resilience And Coping In The Adolescent And Young Adult With Type 1 Diabetes, Debra L. Messinger Aug 2017

Resilience And Coping In The Adolescent And Young Adult With Type 1 Diabetes, Debra L. Messinger

Seton Hall University Dissertations and Theses (ETDs)

There is a need to understand the roles coping strategies play in enhancing resilience in adolescents and young adults with type 1 diabetes between the ages of 18-30. The purpose of this study was to examine the relationships between and among positive, protective coping strategies (courageous coping), negative coping strategies (defensive coping), and resilience. The Resilience in Illness Model (Haase, Kinter, Monahan, & Robb, 2014) was the theoretical model which guided this research.

A convenience sample was recruited via diabetes organizations’ Facebook and Forum pages, a College Diabetes Network chapter meeting, and Juvenile Diabetes Research Foundations’ (JDRF) sponsored events. Data were ...


The Fight Against Breast Cancer: A Policy And Programmatic Approach, Nandi Robinson Aug 2017

The Fight Against Breast Cancer: A Policy And Programmatic Approach, Nandi Robinson

Master's Projects and Capstones

Abstract

Breast cancer continues to remain a significant health issue for women. Previously thought to only occur among postmenopausal women, breast cancer has impacted women of different ages; and rates of breast cancer have various impacts among different ethnic groups. For women living in a toxic environment, many of them have become the new wave of breast cancer cases. Screening and detection have succeeded in decreasing mortality rates. However, more research is needed in finding an efficient method of treatment. In the effort to assist in the fight against breast cancer through a policy and programmatic angle, I am fulfilling ...


The Role Of Mas-Related G-Protein Receptor X2 (Mrgprx2) On Neuropeptide Induced Reponses In Human Mast Cells, Wichayapha Manorak Aug 2017

The Role Of Mas-Related G-Protein Receptor X2 (Mrgprx2) On Neuropeptide Induced Reponses In Human Mast Cells, Wichayapha Manorak

Dental Theses

Rationale: Substance P (SP) and hemokinin-1 (HK-1) are neuropeptides (NPs) that promote inflammatory responses by signaling through the neurokinin-1 receptor (NK-1R). Antagonists of NK-1R are highly effective in allergic inflammation and airway hyperresponsiveness in mice but lack efficacy in humans. The reason for this difference is unknown. Human mast cells express both the NK-1R and Mas-related G protein receptor X2 (MRGPRX2) which are both activated by SP. The objective of this study was to determine if HK-1 activates human mast cells via MRGPRX2. Moreover, since MRGPRX2 contains a cholesterol recognition amino acid consensus (CRAC) domain the interaction between MRGPRX2 and ...


Outcomes Of An Integrated Approach To Speed And Strength Training With An Elite-Level Sprinter, Eric D. Magrum Aug 2017

Outcomes Of An Integrated Approach To Speed And Strength Training With An Elite-Level Sprinter, Eric D. Magrum

Electronic Theses and Dissertations

The purpose of this study was to observe changes in sprint velocity, ground contact time, and peak force demonstrated by a competitive sprinter following an integrated approach to speed development and strength training. As part of an ongoing monitoring procedure the participant completed 20m sprint testing through an optical measurement system and isometric-strength testing before and after each phase of training. Sprint velocity, ground contact time and peak force were analysed using Tau-U, smallest worthwhile and percent change statistics. Results indicate sprinting velocity statistically improved while changes in peak force were practically significant and ground contact time remained trivial throughout ...


Added Sugar Consumption Among College Students, Maram Murad Aug 2017

Added Sugar Consumption Among College Students, Maram Murad

Theses & Dissertations

Added sugar consumption has been increasing in all age groups in the United States and worldwide, with the greatest increase in young adults. College-age years are a critical period in the young adult's life where many habits develop, including nutrition and food choices. An understanding of college-age students’ attitudes and behaviors toward added sugar consumption might help predict added sugar consumption within this population. This was a quantitative study of traditional-aged college students' added sugar consumption through a convenience sample at a private university in San Antonio, TX. A survey was administrated to undergraduate students at different classes. Subjects ...


Metabolic Regulation Of Cellular Signaling, Rashid John Darbandi Aug 2017

Metabolic Regulation Of Cellular Signaling, Rashid John Darbandi

Theses and Dissertations (ETD)

Using the biochemically tractable Xenopus oocyte model system, we have previously characterized a novel metabolic regulation of cell death. We found that glucose-6-phosphate (G6P) via the pentose phosphate pathway leads to increased nicotinamide adenine dinucleotide phosphate (NADPH) levels, a subsequent increase in cytosolic acetyl-coenzyme A and activation of Ca2+/calmodulin-dependent protein kinase II (CaMKII). We recently identified coenzyme A (CoA), derived from the breakdown of acetyl-CoA, as the key metabolic signal that mediates a novel mechanism of calmodulindependent activation of CaMKII. CoA binds directly to the calmodulin (CaM) binding domain (CaMBD) of CaMKII resulting in its activation and downstream inhibitory ...


Data On The Effect Of Sex On The Size, Cellular Content, And Neuronal Density Of The Developing Brain In Mice Exposed To Isoflurane And Carbon Monoxid, L Wang, A Wang, W W. Supplee, K Koffler, Y Cheng, Z M.N. Quezado, R J. Levy Aug 2017

Data On The Effect Of Sex On The Size, Cellular Content, And Neuronal Density Of The Developing Brain In Mice Exposed To Isoflurane And Carbon Monoxid, L Wang, A Wang, W W. Supplee, K Koffler, Y Cheng, Z M.N. Quezado, R J. Levy

Anesthesiology and Critical Care Medicine Faculty Publications

The data presented here detail the changes in size, cellular content, and neuronal density of the developing brain over time with respect to sex in C57Bl/6 mice following neonatal exposure to isoflurane, carbon monoxide, or their combination. Specifically, brain weight- and brain volume-to-body weight ratios are presented, representative immunoblots of whole brain cell-specific protein content are depicted, and quantification of the number of neurons in the primary somatosensory cortex and CA3 region of the hippocampus are shown. Three discrete postnatal time points are represented: P7 (prior to exposure), P14 (one-week post exposure), and P42-56 (5–7 weeks post exposure ...


‘You Do Not Cross Them’: Hierarchy And Emotion In Doctors' Narratives Of Power Relations In Specialist Training, Sophie Crowe, Nicholas Clarke, Ruairi F. Brugha Aug 2017

‘You Do Not Cross Them’: Hierarchy And Emotion In Doctors' Narratives Of Power Relations In Specialist Training, Sophie Crowe, Nicholas Clarke, Ruairi F. Brugha

Epidemiology and Public Health Medicine Articles

Studies of medical education often focus on experiences and socialisation processes among undergraduate students, with fewer examining emotionality among postgraduate trainees. This article explores the relationship between power and emotion, questioning how affective relations between senior and junior doctors are patterned on the hierarchical structure of medicine. The study employs qualitative methods of in-depth, face-to-face and telephone interviews with fifty doctors at initial and advanced stages of specialist postgraduate training in teaching hospitals across Ireland, conducted between May and July, 2015. The study found that respect for hierarchy, anger and fear, intimidation, and disillusion were key themes in participants' narratives ...


Evaluating Effective Communication Methods: Improving Internal Communication, Amber L. Suthers Aug 2017

Evaluating Effective Communication Methods: Improving Internal Communication, Amber L. Suthers

Electronic Theses and Dissertations

Relaying information from a Chief Communications Officer (CIO), or centralized communications departments to hospital employees is not always efficient or effective. Employees may not be informed of important changes to department protocols or hospital policies. The purpose of the study was to determine the most efficient and effective forms of internal communications in the hospital setting.

A total of 83 surveys were mailed to communication officers working in Tennessee hospitals in and east of Nashville. Sixteen communication officers responded. This low response rate may be attributed to poor designation of communication responsibilities and an abdication of responsibilities to an off ...


Functionally Pathogenic Ears2 Variants In Vitro May Not Manifest A Phenotype In Vivo, Nathan Mcneill, Alessia Nasca, Aurelio Reyes, Benjamin Lemoine, Brandi Cantarel, Adeline Vanderver, Raphael Schiffmann, Daniele Ghezzi Aug 2017

Functionally Pathogenic Ears2 Variants In Vitro May Not Manifest A Phenotype In Vivo, Nathan Mcneill, Alessia Nasca, Aurelio Reyes, Benjamin Lemoine, Brandi Cantarel, Adeline Vanderver, Raphael Schiffmann, Daniele Ghezzi

Neurology Faculty Publications

Objective: To investigate the genetic etiology of a patient diagnosed with leukoencephalopathy, brain calcifications, and cysts (LCC).

Methods: Whole-exome sequencing was performed on a patient with LCC and his unaffected family members. The variants were subject to in silico and in vitro functional testing to determine pathogenicity.

Results: Whole-exome sequencing uncovered compound heterozygous mutations in EARS2, c.328G>A (p.G110S), and c.1045G>A (p.E349K). This gene has previously been implicated in the autosomal recessive leukoencephalopathy with thalamus and brainstem involvement and high lactate (LTBL). The p.G110S mutation has been found in multiple patients with LTBL. In ...


Pap.Shotput.Ijss.7.11.17._Abstract.Pdf, Marcus Dolan, Trish Sevene, Joe Berning, Chad Harris, Mike Climstein, Kent Adams, Mark Debeliso Jul 2017

Pap.Shotput.Ijss.7.11.17._Abstract.Pdf, Marcus Dolan, Trish Sevene, Joe Berning, Chad Harris, Mike Climstein, Kent Adams, Mark Debeliso

Mike Climstein

No abstract provided.


Enhancing The Well-Being Of Older Adults And Young Adults With Developmental Disabilities Through Participation In An Intergenerational Community Garden: Participatory Action Research, Diane L. Keen Jul 2017

Enhancing The Well-Being Of Older Adults And Young Adults With Developmental Disabilities Through Participation In An Intergenerational Community Garden: Participatory Action Research, Diane L. Keen

Doctorate of Nursing Science Dissertations

The purpose of this Participatory Action Research (PAR) study was to discover ways to enhance well-being in young adults with DD and older adults in the Oak Grove community. This dissertation details how PAR was used in the Oak Grove community to identify ways to enhance purpose and meaningful activity for older adults while developing positive relationships with younger adults with DD through qualitative methods.

Ryff and Keyes (1995) discovered that although some elements of well-being remain stable as a person ages, purpose-in-life drops significantly in older adults. In addition, young adults with developmental disabilities (DD) lack meaningful relationships, which ...


Racial Differences In Neighborhood Perceptions And Their Influences On Physical Activity Among Urban Older Women, Wenjun Li, Elizabeth Procter-Gray, Gretchen A. Youssef, Scott E. Crouter, Jie Cheng, Kristen Brown, Linda C. Churchill, Anthony Clarke, Judith K. Ockene, Michelle F. Magee Jul 2017

Racial Differences In Neighborhood Perceptions And Their Influences On Physical Activity Among Urban Older Women, Wenjun Li, Elizabeth Procter-Gray, Gretchen A. Youssef, Scott E. Crouter, Jie Cheng, Kristen Brown, Linda C. Churchill, Anthony Clarke, Judith K. Ockene, Michelle F. Magee

Judith K. Ockene

Background: Proper levels of physical activity (PA) are important to healthy aging. Little is known about racial differences in influences of neighborhood perceptions (NP) on PA and use of neighborhood resources among community-dwelling older women.

Materials and methods: In 2014 and 2015, 49 white and 44 black women of age 65 and older living in Washington, DC were queried about their PA, NP, use of neighborhood resources and sociodemographic characteristics. They wore an accelerometer and a Global Positioning System device concurrently for 7 consecutive days. Data were analyzed by race.

Results: Compared to Whites, Blacks had lower NP scores (71 ...


Racial Differences In Neighborhood Perceptions And Their Influences On Physical Activity Among Urban Older Women, Wenjun Li, Elizabeth Procter-Gray, Gretchen A. Youssef, Scott E. Crouter, Jie Cheng, Kristen Brown, Linda C. Churchill, Anthony Clarke, Judith K. Ockene, Michelle F. Magee Jul 2017

Racial Differences In Neighborhood Perceptions And Their Influences On Physical Activity Among Urban Older Women, Wenjun Li, Elizabeth Procter-Gray, Gretchen A. Youssef, Scott E. Crouter, Jie Cheng, Kristen Brown, Linda C. Churchill, Anthony Clarke, Judith K. Ockene, Michelle F. Magee

Wenjun Li

Background: Proper levels of physical activity (PA) are important to healthy aging. Little is known about racial differences in influences of neighborhood perceptions (NP) on PA and use of neighborhood resources among community-dwelling older women. Materials and methods: In 2014 and 2015, 49 white and 44 black women of age 65 and older living in Washington, DC were queried about their PA, NP, use of neighborhood resources and sociodemographic characteristics. They wore an accelerometer and a Global Positioning System device concurrently for 7 consecutive days. Data were analyzed by race. Results: Compared to Whites, Blacks had lower NP scores (71 ...


The Feasibility Of Incentivizing Participation In An Online Social Network Weight Loss Program, Sherry L. Pagoto, Molly E. Waring, Effie Olendzki, Jessica L. Oleski, Christine N. May, Martinus M. Evans Jul 2017

The Feasibility Of Incentivizing Participation In An Online Social Network Weight Loss Program, Sherry L. Pagoto, Molly E. Waring, Effie Olendzki, Jessica L. Oleski, Christine N. May, Martinus M. Evans

Molly E. Waring

Engagement in online social network-delivered weight loss interventions is a predictor of weight loss. Incentivizing engagement in a subset of participants may increase group engagement and subsequent weight loss. In a pilot feasibility trial, 56 adults with obesity were randomized to two Facebook-delivered weight loss interventions, one had 10% users incentivized to engage daily and the other did not. We compared conditions on engagement and weight loss, and then compared incentivized users and natural high engagers on weight loss. Participants were 46.3 (SD: 10.3) years and 89% female. The incentivized user condition had greater total engagement (p=0 ...


The Role Of Attitude, Control And Intention To Explain Fruit And Vegetable Intake Among Racial/Ethnic Minority Women With Low Socioeconomic Status, Michele Debiasse, Deborah J. Bowen, Sherry L. Pagoto, Joseph M. Massaro, N. Istfan, Lisa M. Quintiliani Jul 2017

The Role Of Attitude, Control And Intention To Explain Fruit And Vegetable Intake Among Racial/Ethnic Minority Women With Low Socioeconomic Status, Michele Debiasse, Deborah J. Bowen, Sherry L. Pagoto, Joseph M. Massaro, N. Istfan, Lisa M. Quintiliani

Sherry L. Pagoto

Objective: Fruit and Vegetable (FV) intake-a modifiable risk factor for chronic diseases-is lower among racial/ethnic minorities and low Socio- Economic Status (SES) groups when compared to other populations. The Theory of Planned Behavior (TPB) is one theoretical model studied to explain and influence individual health behaviors, including FV intake, in middle class populations, but not exclusively in diverse, low SES groups. This cross-sectional study evaluated the utility of select TPB variables to explain intention to consume and intake of FV in this population.

Design: Demographics, BMI, select TPB variables, and FV intake were measured via survey. Bivariate analyses were ...


Slipbuddy: A Mobile Health Intervention To Prevent Overeating, Bengisu Tulu, Carolina Ruiz, Joshua Allard, Joseph Acheson, Andrew Busch, Andrew Roskusku, Gage Heeringa, Victor Jaskula, Jessica Oleski, Sherry L. Pagoto Jul 2017

Slipbuddy: A Mobile Health Intervention To Prevent Overeating, Bengisu Tulu, Carolina Ruiz, Joshua Allard, Joseph Acheson, Andrew Busch, Andrew Roskusku, Gage Heeringa, Victor Jaskula, Jessica Oleski, Sherry L. Pagoto

Sherry L. Pagoto

Obesity is one of the top health issues around the globe. Rapid adoption of smartphones presents an opportunity for delivering technology-based interventions that are designed to tackle behaviors that contribute to weight gain. Research shows that the vast majority of weight loss apps in the market place do not go beyond deploying tracking based strategies that are burdensome to the users. In this study, we present a new mobile app and an intervention system called SlipBuddy that puts less burden on users and implements stimulus control strategy to help users lose weight. We describe the SlipBuddy system in detail and ...


From Lucy To Kadanuumuu: Balanced Analyses Of Australopithecus Afarensis Assemblages Confirm Only Moderate Skeletal Dimorphism, Philip L. Reno, C Owen Lovejoy Jul 2017

From Lucy To Kadanuumuu: Balanced Analyses Of Australopithecus Afarensis Assemblages Confirm Only Moderate Skeletal Dimorphism, Philip L. Reno, C Owen Lovejoy

Philip Reno

Sexual dimorphism in body size is often used as a correlate of social and reproductive behavior in Australopithecus afarensis. In addition to a number of isolated specimens, the sample for this species includes two small associated skeletons (A.L. 288-1 or "Lucy" and A.L. 128/129) and a geologically contemporaneous death assemblage of several larger individuals (A.L. 333). These have driven both perceptions and quantitative analyses concluding that Au. afarensis was markedly dimorphic. The Template Method enables simultaneous evaluation of multiple skeletal sites, thereby greatly expanding sample size, and reveals that A. afarensis dimorphism was similar to that ...


A Penile Spine/Vibrissa Enhancer Sequence Is Missing In Modern And Extinct Humans But Is Retained In Multiple Primates With Penile Spines And Sensory Vibrissae, Philip L. Reno, Cory Y Mclean, Jasmine E Hines, Terence D Capellini, Gill Bejerano, David M Kingsley Jul 2017

A Penile Spine/Vibrissa Enhancer Sequence Is Missing In Modern And Extinct Humans But Is Retained In Multiple Primates With Penile Spines And Sensory Vibrissae, Philip L. Reno, Cory Y Mclean, Jasmine E Hines, Terence D Capellini, Gill Bejerano, David M Kingsley

Philip Reno

Previous studies show that humans have a large genomic deletion downstream of the Androgen Receptor gene that eliminates an ancestral mammalian regulatory enhancer that drives expression in developing penile spines and sensory vibrissae. Here we use a combination of large-scale sequence analysis and PCR amplification to demonstrate that the penile spine/vibrissa enhancer is missing in all humans surveyed and in the Neandertal and Denisovan genomes, but is present in DNA samples of chimpanzees and bonobos, as well as in multiple other great apes and primates that maintain some form of penile integumentary appendage and facial vibrissae. These results further ...