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Articles 31 - 60 of 215989

Full-Text Articles in Medicine and Health Sciences

The Wingate Anaerobic Test: A Comprehensive Literature Review And Update On Reference Values In Athletes, Caleb Christie Aug 2021

The Wingate Anaerobic Test: A Comprehensive Literature Review And Update On Reference Values In Athletes, Caleb Christie

All Graduate Plan B and other Reports

The Wingate Anaerobic test (WAnT) was developed in the 1970s as a measurement of lower extremity anaerobic power (Ayalon, Inbar, Bar-Or, 1974) and has long been used as a measurement tool in athletes, who are often defined by numbers. While numbers are not able to entirely predict or evaluate athletic ability, they are often used as a tool to predict or rate athletes. The WAnT has long been a gold standard in evaluating lower extremity power, which is a highly valuable aspect of many sprint and power-driven sports (e.g., hockey, football, or track and field). The WAnT was originally ...


Test-Retest Of The 5-Minute Psychomotor Vigilance Test, Katharine Dennison Aug 2021

Test-Retest Of The 5-Minute Psychomotor Vigilance Test, Katharine Dennison

All Graduate Plan B and other Reports

The purpose of this study was to evaluate the reliability of many variables in the 5-minute Psychomotor Vigilance Test (PVT). Many studies have looked at the validity of a 5-minute PVT, but few so far have looked at reliability. For this study, 13 adult females who worked 12-hr shifts were recruited to complete a two trial day study. The first trial day, the subjects submitted health questionnaire followed by a self-reported sleepiness scale and then a 5-minute PVT. The second trial session the subjects only competed the sleepiness scale followed by the 5-minute PVT. After analyzing the data, it was ...


Milk Exosomes: Nature's Abundant Nanoplatform For Theranostic Applications, Benilde Adriano, Nycol Cotto, Neeraj Chauhan, Meena Jaggi, Subhash C. Chauhan, Murali M. Yallapu Aug 2021

Milk Exosomes: Nature's Abundant Nanoplatform For Theranostic Applications, Benilde Adriano, Nycol Cotto, Neeraj Chauhan, Meena Jaggi, Subhash C. Chauhan, Murali M. Yallapu

School of Medicine Publications and Presentations

Exosomes are a unique subpopulation of naturally occurring extracellular vesicles which are smaller intracellular membrane nanoparticle vesicles. Exosomes have proven to be excellent nanocarriers for carrying lipids, proteins, mRNAs, non-coding RNAs, and DNAs, and disseminating long-distance intercellular communications in various biological processes. Among various cell-line or biological fluid derived exosomes, milk exosomes are abundant in nature and exhibit many nanocarrier characteristics favorable for theranostic applications. To be an effective delivery carrier for their clinical translation, exosomes must inbuilt loading, release, targeting, and imaging/tracking characteristics. Considering the unmet gaps of milk exosomes in theranostic technology it is essential to focus ...


Stream Sediment Monitoring In Morehead Kentucky, Kristopher Krolikowski, Jen O'Keefe Jul 2021

Stream Sediment Monitoring In Morehead Kentucky, Kristopher Krolikowski, Jen O'Keefe

2021 Celebration of Student Scholarship - Oral Presentations

Sediment loads in stream systems play a big role in how overall runoff behaves. Streams naturally transport sediment at various ratios depending on precipitation. When vegetation is removed in upstream environments, sediment loads on streams increase. Sudden increases of sediments in streams can cause many issues, such as flooding or stream re-direction. In Morehead, KY, large-scale logging operations on the ridge above Knapp Avenue and on the ridge above the north end of Allen Avenue have caused increased sediment load in a small stream called Oxley Branch. This stream flows south parallel to Knapp Avenue and along the eastern property ...


The Nature And Role Of Perceived Threats In User Resistance To Healthcare Information Technology: A Psychological Reactance Theory Perspective, Madison N. Ngafeeson, Joseph A. Manga Jul 2021

The Nature And Role Of Perceived Threats In User Resistance To Healthcare Information Technology: A Psychological Reactance Theory Perspective, Madison N. Ngafeeson, Joseph A. Manga

Information Systems Faculty Publications and Presentations

The efforts of the United States government in the past 15 years have included harnessing the power of health information technology (HIT) to improve legibility, lessen medical errors, keep costs low, and elevate the quality of healthcare. However, user resistance is still a barrier to overcome in order to achieve desired outcomes. Understanding the nature of resistance is key to successfully increasing the adoption of HIT systems. Previous research has showed that perceived threats are a significant antecedent of user resistance; however, its nature and role have remained vastly unexplored. This study uses the psychological reactance theory to explain both ...


Greater Belief In Science Predicts Mask-Wearing Behavior During Covid-19, Morgan D. Stosic, Shelby Helwig, Mollie A. Ruben Jul 2021

Greater Belief In Science Predicts Mask-Wearing Behavior During Covid-19, Morgan D. Stosic, Shelby Helwig, Mollie A. Ruben

Teaching, Learning & Research Documents

Coronavirus disease (COVID-19) pandemic impacted both the physical and psychological aspects of people's lives. Personality traits are one of the factors that explain the diverse responses to stressful situations. This study aimed to investigate whether five-factor and maladaptive personality traits are associated with depressive and anxiety symptoms, suicide risk, self-reported COVID-19 symptoms, and preventive behaviors during the COVID-19 pandemic, comprehensively.


Diversity In Community College Registered Nursing Education, Sergio Hernández Del Cid Jun 2021

Diversity In Community College Registered Nursing Education, Sergio Hernández Del Cid

Ed.D. Dissertations in Practice/Capstone Projects

The United States is currently facing a shortage of trained professionals in many fields such as Science, Technology, Engineering, and Nursing (Allen-Ramdial & Campbell, 2014; Georgetown University, 2020). As a result, current U.S. nursing student demographics do not mirror the populations they serve (Gooden, Porter, Gonzalez, & Mims, 2001). Research has shown the positive impact a diverse nursing staff has on patient care (Gooden, Porter, Gonzalez, & Mims, 2001). Representative care and cultural awareness translate to better patient outcomes especially for patients from marginalized and underrepresented communities (Woods-Giscombe, Rowsey, Kneipp, Lackey, & Bravo, 2019). Community colleges play a critical role in the supply of registered nurses within the U.S. (Bissett, 1995). For colleges to better address this shortcoming and have a positive effect on patient outcomes, colleges must evaluate current pathway and persistence practices. Additionally, a greater effort must be made to reevaluate application requirements and admissions processes to counter any failings in the current colonial higher education methodologies (Espinosa, 2011; Patel, 2016). The literature indicates two major bottlenecks in diversifying nursing students. First, nursing in the U.S. has historically been perceived as female-dominated profession, and the second bottleneck is the entry requirements and gap in outreach to marginalized and underrepresented (MUR) communities (Aynaci & Gulmez, 2019; Oyana, et al., 2015; Pacquiao, D. (2007). Potential students are often not ...


Human Kit+ Myeloid Cells Facilitate Visceral Metastasis By Melanoma., Chun I. Yu, Jan Martinek, Te-Chia Wu, Kyung In Kim, Joshy George, Elaheh Ahmadzadeh, Richard S. Maser, Florentina Marches, Patrick Metang, Pierre Authie, Vanessa K P Oliveira, Victor G Wang, Jeffrey Chuang, Paul Robson, Jacques Banchereau, Karolina Palucka Jun 2021

Human Kit+ Myeloid Cells Facilitate Visceral Metastasis By Melanoma., Chun I. Yu, Jan Martinek, Te-Chia Wu, Kyung In Kim, Joshy George, Elaheh Ahmadzadeh, Richard S. Maser, Florentina Marches, Patrick Metang, Pierre Authie, Vanessa K P Oliveira, Victor G Wang, Jeffrey Chuang, Paul Robson, Jacques Banchereau, Karolina Palucka

Faculty Research 2021

Metastasis of melanoma significantly worsens prognosis; thus, therapeutic interventions that prevent metastasis could improve patient outcomes. Here, we show using humanized mice that colonization of distant visceral organs with melanoma is dependent upon a human CD33+CD11b+CD117+ progenitor cell subset comprising <4% of the human CD45+ leukocytes. Metastatic tumor-infiltrating CD33+ cells from patients and humanized (h)NSG-SGM3 mice showed converging transcriptional profiles. Single-cell RNA-seq analysis identified a gene signature of a KIT/CD117-expressing CD33+ subset that correlated with decreased overall survival in a TCGA melanoma cohort. Thus, human CD33+CD11b+CD117+ myeloid cells represent a novel candidate biomarker as well as a therapeutic target for metastatic melanoma.


Mental Health Outcomes Of Various Types Of Fear Among University Students Who Have An Undocumented Legal Status During The Donald Trump Presidency, Liliana Campos Jun 2021

Mental Health Outcomes Of Various Types Of Fear Among University Students Who Have An Undocumented Legal Status During The Donald Trump Presidency, Liliana Campos

Doctoral Dissertations

Having an undocumented legal status is a risk factor for mental health conditions such as depression and anxiety among university students. Much of the literature on the experiences of university students who hold an undocumented legal status has primarily focused on better understanding the educational, social, financial, and legal challenges among undergraduate students. The literature has addressed how some of these difficulties impact components of their social and mental health wellness. Yet, there is still a dearth of research focused on further understanding the experiences of students who hold an undocumented legal status from a psychological perspective, and specifically, with ...


Changes In Student Behaviors And Policy Opinion Regarding E-Cigarettes At A Kentucky University From 2014 To 2018, Jason W. Marion, Alina Strand, Elliott Baldridge Jun 2021

Changes In Student Behaviors And Policy Opinion Regarding E-Cigarettes At A Kentucky University From 2014 To 2018, Jason W. Marion, Alina Strand, Elliott Baldridge

EKU Faculty and Staff Scholarship

The behaviors and opinions regarding e-cigarette use and campus policies prohibiting vaping vary greatly among college students nationally. Kentucky is one of the four U.S. states with the highest tobacco use prevalence, and characterizing e-cigarette use, trends and policy opinions among Kentucky undergraduates may inform interventions. To characterize population-level differences in e-cigarette-related behaviors and policy opinions among undergraduates from 2014 to 2018, results from two cross-sectional surveys (2014 and 2018) from a public regional university in south-central Kentucky were analyzed. Students from randomly selected undergraduate general studies courses completed a 5-minute in-class survey. Data were obtained from 514 and ...


Sense Of Effort Is Distorted In People With Chronic Low Back Pain, Michel W. Coppieters, Jesper Andersen, Håvard Selbæk, Kjell Herland, Rahma Ajja, Harald Markussen, Paul W. Hodges Jun 2021

Sense Of Effort Is Distorted In People With Chronic Low Back Pain, Michel W. Coppieters, Jesper Andersen, Håvard Selbæk, Kjell Herland, Rahma Ajja, Harald Markussen, Paul W. Hodges

All Works

Background: Proprioceptive deficits in people with low back pain (LBP) have traditionally been attributed to altered paraspinal muscle spindle afference and its central processing. Studies conducted in the upper limb demonstrated that sense of effort is also an important source of kinaesthetic information. Objectives: To better understand proprioceptive deficits in people with chronic LBP (cLBP), this study aimed to test whether sense of effort is affected in people with cLBP. Design: Cross-sectional study. Method: Fourteen participants with cLBP and fourteen healthy participants performed a 120 s force matching task with their trunk extensor muscles at a low intensity. Results: When ...


Respecting The Spectrum: Creating A Gender Inclusive Structured Diagnostic Intake Interview, Natalia Andino-Rivera Jun 2021

Respecting The Spectrum: Creating A Gender Inclusive Structured Diagnostic Intake Interview, Natalia Andino-Rivera

Dissertations

Transgender and nonbinary (TNB) people, more than ever, are in need of and actively seeking out services in order to cope with the reality of being transgender in the United States. This includes requiring assistance from local and federal governmental systems that do not provide protections for equal housing, workplace discrimination, and healthcare provisions, much less hate crime investigation and prosecution. In 2011, 75% of transgender people were or had been in therapy in the past, with a further 14% intending to participate in therapy in the future. Recently, the newly elected President Joseph Biden issued an executive order (EO ...


Systematic Review: The Effect Of Hearing Aids On Balance And Falls, Natalia Beatriz Pagan-Guadalupe Jun 2021

Systematic Review: The Effect Of Hearing Aids On Balance And Falls, Natalia Beatriz Pagan-Guadalupe

Dissertations, Theses, and Capstone Projects

Background: The population of individuals 65 years old is increasing and falls are one of the most prevalent causes of disabilities among this population. Recent studies have found association between neural hearing losses and increased risk of falls, suggesting that hearing is an important input that assist visual, proprioceptive and vestibular inputs in maintaining balance. Hearing aids are known to be beneficial to improve access to sound; however, it is very limited the research regarding the effects of amplification on balance and risk of falls.

Objectives: This systematic review intends to gather and analyze all the research available regarding the ...


Alcohol And Its Long-Term Effects On Hearing Loss: A Systematic Review, Talia Sowalsky Jun 2021

Alcohol And Its Long-Term Effects On Hearing Loss: A Systematic Review, Talia Sowalsky

Dissertations, Theses, and Capstone Projects

Objective: To review the literature on potential permanent effects of long-term alcohol consumption on hearing status in adults 40 years of age and older.

Study Design: Systematic review of prospective and retrospective studies; meta-analysis of case-controlled studies.

Methods: One researcher independently reviewed MEDLINE (January 1, 2000-May 1, 2019), CINAHL (January 1, 2000-May 1, 2019), PubMed (January 1, 2000-May 1, 2019), and Web of Science (January 1, 2000-May 1, 2019). A manual reference search was additionally conducted. Randomized controlled trials, prospective cohort studies, consecutive/non-consecutive case series, and retrospective reviews in which a clear definition of hearing loss was stated were ...


Machine Learning Classification Of Traumatic Brain Injury Patients Versus Healthy Controls Using Arterial Spin Labeled Perfusion Mri, Vanessa I. Grass Jun 2021

Machine Learning Classification Of Traumatic Brain Injury Patients Versus Healthy Controls Using Arterial Spin Labeled Perfusion Mri, Vanessa I. Grass

Dissertations, Theses, and Capstone Projects

Traumatic brain injury (TBI) is one of the most common causes of death and disability worldwide, yet accurate in vivo detection of TBI neuropathology remains challenging due to complexities in the structural and functional changes observed post-injury as well as limitations in conventional neuroimaging modalities. Although advanced neuroimaging techniques such as arterial spin labeling (ASL) can noninvasively assess cerebral blood flow (CBF) changes observed post-injury, this technique is underutilized in TBI research partly due to the low signal-to-noise-ratio (SNR) inherent in ASL imaging. The aim of the current study is to examine the use of machine learning, specifically a Support ...


Optimizing Communication In Palliative And Hospice Care: A Toolkit For Audiologists, Sherry E. Queen Jun 2021

Optimizing Communication In Palliative And Hospice Care: A Toolkit For Audiologists, Sherry E. Queen

Dissertations, Theses, and Capstone Projects

The prevalence of hearing loss increases with age, with age-related hearing loss (ARHL) being one of the most prevalent forms of sensory decline in older adults. Hearing loss is often overlooked in medical settings including palliative and hospice care. Screening for hearing loss in these settings is rare as is formal staff training on assessing and managing hearing loss in palliative and hospice care. An evidence-based toolkit for integrating audiologists into end-of-life care protocols is presented. This toolkit was developed to optimize communication in palliative and hospice care for patients, caregivers, audiologists, physicians, and other palliative care staff. Effective communication ...


Positive Symptoms Of Schizophrenia And Suicide: A Systematic Review Of Gender, Race/Ethnicity, And Premorbid Iq Variables, Susan Diann Paschall Jun 2021

Positive Symptoms Of Schizophrenia And Suicide: A Systematic Review Of Gender, Race/Ethnicity, And Premorbid Iq Variables, Susan Diann Paschall

Dissertations

Schizophrenia is an exceptionally debilitating mental disorder. Its effects permeate all facets of psychosocial functioning and it is associated with premature mortality. As such, suicide is of clinical concern. Positive symptoms such as hallucinations and delusions may influence the risk of suicide among individuals diagnosed with schizophrenia, but additional research is necessary, as the limited literature on this topic is dated and includes heterogeneous results. Early recognition of and intervention for suicide risk factors, such as the presence of positive symptoms of psychosis, may reduce mortality rates for individuals with schizophrenia. The present literature review examined the role of gender ...


Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth May 2021

Characterization Of Time-Variant And Time-Invariant Assessment Of Suicidality On Reddit Using C-Ssrs, Manas Gaur, Vamsi Aribandi, Amanuel Alambo, Ugur Kursuncu, Krishnaprasad Thirunarayan, Jonathan Beich, Jyotishman Pathak, Amit Sheth

Publications

Suicide is the 10th leading cause of death in the U.S (1999-2019). However, predicting when someone will attempt suicide has been nearly impossible. In the modern world, many individuals suffering from mental illness seek emotional support and advice on well-known and easily-accessible social media platforms such as Reddit. While prior artificial intelligence research has demonstrated the ability to extract valuable information from social media on suicidal thoughts and behaviors, these efforts have not considered both severity and temporality of risk. The insights made possible by access to such data have enormous clinical potential - most dramatically envisioned as a trigger ...


Deprescribing In The Hospice Population, Who Is Eligible And Who Is Agreeable: A Quality Improvement Project, Ashlee Nicole Smith May 2021

Deprescribing In The Hospice Population, Who Is Eligible And Who Is Agreeable: A Quality Improvement Project, Ashlee Nicole Smith

Doctor of Nursing Practice Final Manuscripts

Current evidence recommends and supports deprescribing medications to reduce polypharmacy in the hospice population. The project aim was to determine accurate percentages of deprescribing at three time periods: before hospice admission, at hospice enrollment, and four weeks post hospice enrollment. This project was a retrospective review of the medication administration record (MAR) of patients admitted into Sharp Hospice from a Sharp Healthcare facility. Sharp Hospice, in California, USA, admitted 164 patients during August 2020. Of those, 34 patients were eligible for inclusion in this retrospective quality improvement review. Prior to discharge from a Sharp facility, the percentage of target medications ...


Association Of Fresh Waterways And Legionella Pneumophila Infection In Eastern Wisconsin: A Case-Control Study, Hannah M. William, Kayla Heslin, Jessica J F Kram, Caroline P. Toberna, Dennis Baumgardner May 2021

Association Of Fresh Waterways And Legionella Pneumophila Infection In Eastern Wisconsin: A Case-Control Study, Hannah M. William, Kayla Heslin, Jessica J F Kram, Caroline P. Toberna, Dennis Baumgardner

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Access To Targeted Online Educational Resources Pre And In Midst Of A Pandemic, Deborah Simpson, Kathryn Denson, Amanda Szymkowski, Debra Mooney, Steven Denson, Edmund H. Duthie, Michael Malone May 2021

Access To Targeted Online Educational Resources Pre And In Midst Of A Pandemic, Deborah Simpson, Kathryn Denson, Amanda Szymkowski, Debra Mooney, Steven Denson, Edmund H. Duthie, Michael Malone

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Xeglyze Drug Review, Alexander Woods, Caroline L. Porter, Steven R. Feldman May 2021

Xeglyze Drug Review, Alexander Woods, Caroline L. Porter, Steven R. Feldman

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Detrimental Oxygen: Oxygen Supplementation In Stemi Patients, Gabrielle Rubin, Namra Butt, Sorabh Kothari, Moustafa Sabri May 2021

Detrimental Oxygen: Oxygen Supplementation In Stemi Patients, Gabrielle Rubin, Namra Butt, Sorabh Kothari, Moustafa Sabri

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Hospitalized Patient Perspectives On Oral Care, Susan Donovan, Michaela Baron, Kate Davey, Ashley O'Connor, Mary Hook May 2021

Hospitalized Patient Perspectives On Oral Care, Susan Donovan, Michaela Baron, Kate Davey, Ashley O'Connor, Mary Hook

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Treatment Outcomes And Program Transition Rates Across Substance Use Treatment Programs, Mindy Waite, Kayla Heslin, Jonathan A. Cook, Michelle Simpson May 2021

Treatment Outcomes And Program Transition Rates Across Substance Use Treatment Programs, Mindy Waite, Kayla Heslin, Jonathan A. Cook, Michelle Simpson

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Enhancing Tools To Aid In Antimicrobial Stewardship Services In A Multi-State Health System, Ann Duy Vo, Meghan Murphy, Dan Persells May 2021

Enhancing Tools To Aid In Antimicrobial Stewardship Services In A Multi-State Health System, Ann Duy Vo, Meghan Murphy, Dan Persells

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Personal Protective Equipment Compliance: A Quality Improvement Initiative, Hilary Brown, Lizabeth Copre, Cathy Larson, Stephanie Spacone-Perez, Laura Albanese, Sandra Weitzner, Mitali Shah, Varsha Gharpure May 2021

Personal Protective Equipment Compliance: A Quality Improvement Initiative, Hilary Brown, Lizabeth Copre, Cathy Larson, Stephanie Spacone-Perez, Laura Albanese, Sandra Weitzner, Mitali Shah, Varsha Gharpure

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Cardiac, Renal And Liver Functionin Neonates With Hypoxic Ischemic Encephalopathy Treated With Therapeutic Hypothermia, Gospodin Stefanov, Timothy Colombo, Lorene Schweig, Preetha Prazad, Ramona Donovan May 2021

Cardiac, Renal And Liver Functionin Neonates With Hypoxic Ischemic Encephalopathy Treated With Therapeutic Hypothermia, Gospodin Stefanov, Timothy Colombo, Lorene Schweig, Preetha Prazad, Ramona Donovan

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Kalmed: Ketamine For Acute Agitation Management In The Emergency Department, Lauren Stambolic, Marc Mcdowell, Dharati Desai, Jaxson Burkins, Nadine Lomotan, Tasneem Ahmed, Stephany Nunez Cruz May 2021

Kalmed: Ketamine For Acute Agitation Management In The Emergency Department, Lauren Stambolic, Marc Mcdowell, Dharati Desai, Jaxson Burkins, Nadine Lomotan, Tasneem Ahmed, Stephany Nunez Cruz

2021 Advocate Aurora Health Scientific Day

No abstract provided.


Emergency Department Pharmacist Led Methicillin Resistant Staphylococcus Aureus (Mrsa) Polymerase Chain Reaction (Pcr) Assay For Vancomycin In Pneumonia, Sabrina Najibi, Yekaterina Antonishina, Stephany Nunez Cruz, Marc Mcdowell, Jaxson Burkins, Nadine Lomotan, Lauren Stambolic, Dharati Desai May 2021

Emergency Department Pharmacist Led Methicillin Resistant Staphylococcus Aureus (Mrsa) Polymerase Chain Reaction (Pcr) Assay For Vancomycin In Pneumonia, Sabrina Najibi, Yekaterina Antonishina, Stephany Nunez Cruz, Marc Mcdowell, Jaxson Burkins, Nadine Lomotan, Lauren Stambolic, Dharati Desai

2021 Advocate Aurora Health Scientific Day

No abstract provided.