Medicine and Health Sciences Commons^™

Associations Of Body Adiposity Index, Body Mass Index, Waist Circumference, And Percentage Of Body Fat In Young Female Emirati Adults, Dalia Haroun, Maryam Darwish, Aseel Ehsanallah

All Works

Body Adiposity Index (BAI), which relies on an individual’s hip circumference and height, was proposed as an alternative anthropometric measurement to Body Mass Index (BMI). Although this measure has been validated across different populations, its accuracy in predicting percent body fat (%BF) in the United Arab Emirates has not yet been assessed. The objective of this study was to examine the association between BAI, BMI, Waist Circumference (WC), and %BF in young female Emirati adults and determine the relative accuracy of BAI when predicting %BF. A retrospective cross-sectional study was conducted among 95 Emirati women between the ages of 17 …

Vitamin D Regulates Covid-19 Associated Severity By Suppressing The Nlrp3 Inflammasome Pathway, Bariaa Khalil, Narjes Saheb Sharif-Askari, Shirin Hafezi, Fatemeh Saheb Sharif-Askari, Fatme Al Anouti, Qutayba Hamid, Rabih Halwani

All Works

Background The role of vitamin D3 (VitD3) in modulating innate and adaptive immunity has been reported in different disease contexts. Since the start of the coronavirus disease-2019 (COVID-19) pandemic, the role of VitD3 has been highlighted in many correlational and observational studies. However, the exact mechanisms of action are not well identified. One of the mechanisms via which VitD3 modulates innate immunity is by regulating the NLRP3-inflammasome pathway, being a main underlying cause of SARS-CoV-2-induced hyperinflammation. Aims and main methods Blood specimens of severe COVID-19 patients with or without VitD3 treatment were collected during their stay in the intensive care …

Associations Between Polycystic Ovary Syndrome (Pcos) And Antibiotic Use: Results From The Uaehfs, Nirmin F. Juber, Abdishakur Abdulle, Amar Ahmad, Fatme Alanouti, Tom Loney, Youssef Idaghdour, Yvonne Valles, Raghib Ali

All Works

Women with polycystic ovary syndrome (PCOS) have a higher susceptibility to infections compared to those without PCOS. Studies evaluating antibiotic use based on PCOS status are scarce. Therefore, we aimed to (i) assess the associations between self-reported PCOS and antibiotic use, and (ii) whether PCOS treatment and the age at PCOS diagnosis modified the associations above. This cross-sectional analysis used the United Arab Emirates Healthy Future Study (UAEHFS) conducted from February 2016 to March 2023 involving 2063 Emirati women aged 18–62 years. We performed ordinal logistic regressions under unadjusted and demographic-health-characteristic-adjusted models to obtain the odds ratios (ORs) and 95% …

Evolution Of Medical Ethics During American Civil War, Luke Love

Poster Presentations

This thesis will explore the relationship between medical ethics and the American Civil War through a microhistorical approach. This includes analyzing the ways in which the physician-patient relationship was conducted and which medical practices were deemed ethical and by whom. Changes that occurred in medical ethics during the war will be analyzed and explained.

The Influence Of Smoothness And Speed Of Stand-To-Sit Movement On Joint Kinematics, Kinetics, And Muscle Activation Patterns, Woohyoung Jeon, Xuanliang Neil Dong, Ashley Dalby, Chung-Hyun Goh

Health and Kinesiology Faculty Publications and Presentations

Background: Stand-to-sit (StandTS) is an important daily activity widely used in rehabilitation settings to improve strength, postural stability, and mobility. Modifications in movement smoothness and speed significantly influence the kinematics, kinetics, and muscle activation patterns of the movement. Understanding the impact of StandTS speed and smoothness on movement control can provide valuable insights for designing effective and personalized rehabilitation training programs.

Research question: How do the smoothness and speed of StandTS movement affect joint kinematics, kinetics, muscle activation patterns, and postural stability during StandTS?

Methods: Twelve healthy younger adults participated in this study. There were two StandTS conditions. In the …

Conversations To Find One’S Truth: Coaching In Medical Student Education, Binata Mukherjee, Jenna Pfleeger, Clista Clanton, Maria Renee Roca Garcia, Gurupreet Khalsa, Haidee Custodio

CoTL 2024 Research Talks

Following coach training for College of Medicine faculty and leadership, the benefits of coaching for inculcating the habit of self-reflection to find one’s truth and create learning paths was recognized. While there was unanimous agreement to implement coaching for medical students, the contributing factors for the success of or barriers to academic medical coaching programs were ambiguous. We embarked on a scoping review to understand how coaching is being used for medical learners, and will share our process and preliminary discoveries.

Classroom-Based Simulation & Clinical Education Innovations Improve Graduate Education, Brenda L. Beverly, Emma A. Townsend

CoTL 2024 Research Talks

Although classroom-based coursework and clinical education activities in speech-language pathology graduate programs strive to link education to relevant practice, gaps persist. Parent-implemented intervention is an evidence-based practice mandated by federal law in early intervention; however, speech-language pathology graduate programs do not provide students with ample opportunities to gain relevant experience. Outcomes from two research studies supported revising classroom and clinical education, increasing educational relevance and professional preparation for students. A qualitative study with focus groups identified key implementation needs that led to the addition of role play simulation in the classroom. A follow-up study supported developing an innovative clinical model …

Graphic Novels As Learning Tools, Leesha Coleman

CoTL 2024 Research Talks

Graphic novels are not just for kids! Graphic novels can be used in nearly every aspect of teaching and learning. This presentation focuses on providing attendees with research on using graphic medicine in the classroom for retention. While the presentation focuses on Graphic Medicine, the principles can be applied to other disciplines.

Using Simulation To Enhance Undergraduate Nursing Education, Lori Prewitt Moore, Candice N. Selwyn

CoTL 2024 Posters

This poster presentation will discuss the implementation of simulation-based education in the undergraduate nursing curriculum to increase preparedness in caring for adolescent patients with symptoms of depression and suicidal ideation. This topic aligns with the conference’s theme by identifying the importance of introducing nursing students to urgent and life-threatening simulated healthcare events prior to graduation. The plan for this presentation is to impart information to others regarding the use of the International Nursing Association for Clinical Simulation and Learning’s standards of best practice when implementing innovative, simulation-based education for nursing students. The outcome and objectives for this presentation is to …

The Effect Of Using A Meal Tracking Smartphone Application In Overweight And Obese Adolescents With Prediabetes Or Type 2 Diabetes To Improve Bmi And Hba1c, Lauren Torhorst

Evidence-Based Practice Project Reports

Obesity has become one of the most common chronic pediatric illnesses worldwide and is closely linked to the onset of prediabetes and subsequent Type 2 Diabetes (T2D); therefore, preventing and treating childhood obesity has become a high priority (Hampl et al., 2023). The purpose of this Evidence-Based Practice (EBP) project is to lower Glycosylated Hemoglobin A1c (HbA1C) and Body Mass Index (BMI) in overweight and obese youth with prediabetes and T2D using a meal tracking smartphone application. The Johns Hopkins Nursing Evidence-Based Practice Model (JHNEBP) was utilized to pilot this project between two pediatric endocrinology offices located in Southeast Wisconsin. …

Does Assisted Living Provide Assistance And Promote Living?, Sheryl Zimmerman, Robyn Stone, Paula Carder, Kali Thomas

Institute on Aging Publications

Assisted living has promised assistance and quality of living to older adults for more than eighty years. It is the largest residential provider of long-term care in the United States, serving more than 918,000 older adults as of 2018. As assisted living has evolved, the needs of residents have become more challenging; staffing shortages have worsened; regulations have become complex; the need for consumer support, education, and advocacy has grown; and financing and accessibility have become insufficient. Together, these factors have limited the extent to which today's assisted living adequately provides assistance and promotes living, with negative consequences for aging …

The 2022 Symposium On Dementia And Brain Aging In Low- And Middle-Income Countries: Highlights On Research, Diagnosis, Care, And Impact, Raj Kalaria, Gladys Maestre, Simin Mahinrad, Daisy Acosta, Rufus Akinyemi, Suvarna Alladi, Ricardo Allegri, Faheem Arshad, Wambui Karanja, Chinedu Momoh

Brain and Mind Institute

Two of every three persons living with dementia reside in low- and middle-incomecountries (LMICs). The projected increase in global dementia rates is expected toaffect LMICs disproportionately. However, the majority of global dementia care costsoccur in high-income countries (HICs), with dementia research predominantly focus-ing on HICs. This imbalance necessitates LMIC-focused research to ensure thatcharacterization of dementia accurately reflects the involvement and specificities ofdiverse populations. Development of effective preventive, diagnostic, and therapeu-tic approaches for dementia in LMICs requires targeted, personalized, and harmonizedefforts. Our article represents timely discussions at the 2022 Symposium on Demen-tia and Brain Aging in LMICs that identified the foremost …

Investigating Pre-Health Students’ Science Identity And The Factors That Influence Them To Change Programs Or Tracks., Taylor Humphreys

College of Arts & Sciences Senior Honors Theses

Retention is a particularly pressing issue for undergraduate students, specifically those in pre-health programs or tracks. This can be affected by a students’ science identity, which is referred to as viewing oneself as a “science person.” This study focused on investigating science identity and influencing factors that can cause program or track change of pre-health students. Previous studies have investigated these factors regarding pre-health students applying to medical school, but this study opened the investigation to a variety of pre-health students and focused on characterizing students’ experiences prior to their health professional school applications. The analysis of peer-led focus group …

Sdf-1Α Mediates Primary Tumor Escape In Glioblastoma Through Activation Of Mesenchymal Transitions., Charles T. Froman-Glover

College of Arts & Sciences Senior Honors Theses

Glioblastoma (GBM), a highly aggressive primary brain tumor originating in glial cells, poses a significant challenge due to its rapid growth and invasive nature within healthy brain tissue.

Current treatments involve surgical resection, chemotherapy, and radiation. These treatments alone are not enough to cure this disease, and a better understanding the mechanics of the tumor micro-environment is imperative to furthering the field of cancer research. This research focuses on understanding the tumor microenvironment's impact, specifically investigating the role of stromal cell-derived factor 1 (SDF-1) mechanics on GBM aggressiveness. SDF-1 is known to facilitate disease progression by facilitating chemotaxis toward the …

A Revised Synthesis Of The Cationic Lipids Dmri And Mlri, Benjamin A. Kostic

College of Arts & Sciences Senior Honors Theses

Lipid nanoparticles (LNPs) are an increasingly utilized method of intracellular delivery for nucleic acids. The COVID-19 vaccines from Moderna and Pfizer-BioNTech have used LNP technology to combat the recent global SARS-CoV-2 pandemic, saving millions of lives.^1,2 These vaccines consist of a lipid formulation that binds to the anionic phosphate groups of mRNAs and serves as an effective way to transport the nucleic acid across membranes into cells.⁹The mRNA encodes a viral protein. When introduced to cells, the viral protein is produced so that the immune system then can generate an appropriate antibody response.³ However, this approach …

Psychiatric Morbidity Among Patients On Treatment For Tuberculosis At A Tertiary Referral Hospital In Western Kenya, Robina Momanyi, Edith Kwobah, Philip Owiti, Henry Nyamogoba, Lukoye Atwoli

Internal Medicine, East Africa

Background Mental disorders account for nine percent of the overall global burden of disease and are among the top ten leading causes of disability. Mental illness and tuberculosis share risk factors including poverty, overcrowding, stigma, poor nutrition, substance use and retro-viral disease co-infection. Presence of mental illness in tuberculosis delays health-seeking, affects drug adherence, increases cost of treatment, prolongs disease duration, lowers quality of life, and increases mortality. Early diagnosis, linkage, and treatment of psychiatric morbidity among patients with tuberculosis would improve outcomes for both. This study thus aimed to determine the prevalence and factors associated with psychiatric morbidity among …

Detection And Extraction Of Pfoa And Pfos Via Mips, Joseph Redding

Senior Honors Theses

Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) are utilized as surfactants in many different materials. With an immensely stable structure due to the presence of carbon-fluorine bonds, PFOA and PFOS are resistant to degradation. Known to persist in water resources, these compounds tend to bioaccumulate and impute toxic effects on human health, such as decreased fertility and immune function. To date, there exists no effective approach to the removal of these lingering compounds. Because of the health risks, there is increasing urgency to devise a means by which to detect and withdraw PFOA and PFOS from the environment. In …

Evaluating The Integration Of Traditional And Western Medicine In Rural Ghana: The Role Of Healers And The Government, Teresa Nicole Lemon

Poster Presentations

A question of pressing importance for the healthcare system in Ghana is the integration between biomedicine, which is unreachable for many rural citizens, and traditional medicine, which fills in the gaps in access for rural and non-rural citizens seeking care and is utilized by 70% of the population. The WHO promotes integrated health systems and created strategies to assist governments in their efforts.

The Ghanaian government did create policies to aid in integration, but their attempt to integrate was unsuccessful. This, along with other factors, has led some scholars to consider the government’s efforts as “tokenistic”; however, they do not …

Dna Methylation Of The Agtr1 Gene In A Hypertensive Population Of Kenyans, Michael M. Roque

Poster Presentations

Cardiovascular disease (CVD), the leading cause of death worldwide, is rapidly increasing in low-and middle-income countries (LMICs), particularly those of Sub-Saharan Africa (SSA)(World Health Organization). Hypertension is the leading risk factor for CVD and is a multifactorial disease with no single genetic cause. Increasingly, evidence indicates that hypertension is predisposed by environmental regulation of genes through heritable, yet modifiable, epigenetic changes to DNA leading to changes in gene expression, e.g. methylation. While understanding the etiology of hypertension in LMICs is a global priority, few epigenetic studies exist from populations living in SSA (Fan). The renin-angiotensin system (RAS) is the primary …

Postural Control In Young Adults With And Without Recurrent Back Pain: Influence Of Symptom Characteristics, Rachel Berns

Student Scholar Symposium Abstracts and Posters

Many individuals with low back pain (LBP) experience episodic symptoms. During symptomatic episodes, individuals with LBP have delayed trunk muscle activation during anticipated postural perturbations, though it's unclear if these postural control changes persist between symptomatic episodes. This study examined anticipatory postural muscle activation in adults with and without recurrent LBP to determine the influence of muscle fatigue and typical symptom characteristics on trunk muscle activation. 55 young adults with a greater than one-year history of recurrent LBP and 30 young adults with no history of LBP were recruited. Electromyography electrodes were placed on their thoracic and lumbar paraspinals, external …

Augmenting Hand And Arm Function For Persons With Hemiparesis, Brooke Stein, Susan Duff, Alison Mckenzie, Bailey Advincula, Isaac An, Annie Jeon, Casey Mcwilliam, Will Potter, Virginia Ruano, Paulina Vokulich, Audrey Howell, Rahul Soangra

Student Scholar Symposium Abstracts and Posters

Background. Hand and arm dysfunction due to neural disorders significantly influences quality of life. Activity-based training has been found to improve function. These improvements could be augmented with transcutaneous spinal cord stimulation (tSCS) due to the modulatory effect it has on spinal and supraspinal networks. Objective. The primary aim is to determine if a 4-week training program will improve hand and arm function. The secondary aim is to determine if the addition of tSCS to a second 4-week training session will further improve function. Design. This is a pre-posttest, controlled trial for persons 10-75 years of age, >6 months post …

Structural Sensorimotor Adaptations In Young Adults With Low Back Pain, Isaac Chrisman, Jo Armour Smith, Rongwen Tain, Kelli G. Sharp, Laura M. Glynn, Linda R. Van Dillen, Jesse V. Jacobs, Steven C. Cramer

Student Scholar Symposium Abstracts and Posters

Chronic low back pain (CLBP) is the largest cause of disability worldwide. There is evidence for regional structural brain adaptation in CLBP. Most studies have investigated middle-aged adults and show decreased grey matter density in pain processing regions. It is not clear if these adaptations are evident early in the lifespan of individuals with CLBP. The purpose of the study was to compare sensorimotor gray matter density in young adults with a history of CLBP with back-healthy controls. 53 young adults with a greater than 1-year history of CLBP and 29 young adults with no history of LBP participated. Clinical …

The Moderating Effect Of Socioeconomic Status And Walkability On The Efficacy Of Physical Activity Interventions, Analisa Vavoso, Vincent Berardi, Marc A. Adams

Student Scholar Symposium Abstracts and Posters

To enable physical activity (PA) interventions to better tailor procedures to participant characteristics, we investigated the role of neighborhood socioeconomic status (SES) and walkability on the differential effectiveness of adaptive versus static activity goals (AG vs. SG) and immediate versus delayed (IR vs. DR) reinforcement in a PA trial.

Data was collected as a part of the WalkIT Arizona study, where healthy, inactive adults (n = 512) were instructed to wear an accelerometer daily for one year and were provided with daily goals for moderate-to-vigorous PA (MVPA). The intersection of goal types (adaptive and static) as well as reinforcement types …

Synthesis Of Thermoresponsive Poly(N-Isopropyl Acrylamide) Based Core-Shell And Hollow Shell Nanogel With Tunable Core And Shell Thickness, Mohamad Hijazi, Molla R. Islam

Student Scholar Symposium Abstracts and Posters

Nanogels have emerged as a notably safer and more effective means for drug delivery, primarily due to their adjustable drug-loading capabilities. Hollow-core nanoparticles offer some unique properties that are desirable for drug delivery applications. Initially, silica core nanoparticles were synthesized using the Stöber process at different temperatures where Tetraethoxysilane (TEOS) undergoes hydrolysis in the presence of ethanol and then a condensation reaction to form silica nanoparticles. Scanning Electron Microscopy (SEM) and Optical Microscopy (OM) analysis revealed that the size of silica core particles varied with the synthesis temperature (300 nm at 30°C to 150 at 60°C). The core silica particles …

Spatiotemporal Gait Parameter Consistency Across Two Days Of Treadmill Walking In Stroke Survivors, Alejandro Aguirre Ramirez, Samantha N. Jeffcoat, Natalia Sanchez, Andrian Kuch

Student Scholar Symposium Abstracts and Posters

Retraining impaired gait is essential in post-stroke recovery. This project aims to determine between day variability of spatiotemporal gait measures in treadmill walking post-stroke to differentiate between changes due to the intervention and measurement errors due to between day test-retest variability. Six individuals post-stroke performed a two-minute walk test at a self-selected speed (SSS) for two consecutive days. SSS was assessed through the six-minute walk test. Reflective markers were placed on anatomical landmarks (van den Bogert et al. 2013). The heel markers were used for step detection. We calculated spatiotemporal parameters: stride length, stride time, step length, stance time, and …

“Pro-Woman, Pro-Life”: Framing Of The Anti-Abortion Movement, Olivia Rivet

Student Scholar Symposium Abstracts and Posters

This project on the “Pro-Woman, Pro-Life" framing of the Anti-Abortion Movement uses James Paul Gee's theoretical lens on discourse analysis. My research corpus is comprised of historical, legislative, news, editorial, and film data. This project focuses on when the term "Pro-Woman" first appeared in the anti-abortion discourse and how it has been used to reinforce the Pro-Life stance. I argue that the phrase -- "Pro-Woman" -- is a discoursal strategy to appeal to women who are ideologically aligned with the Pro-Choice movement. According to the Pro-Woman, Pro-Life framework, no "feminist" would want to support a practice, such as abortion, that …

Alcohol Use Disorder: Behaviors And Comorbidities In Recovery, Ryann Schochet

Student Scholar Symposium Abstracts and Posters

The purpose of this study was to determine the connection between length of sobriety, for people with alcohol use disorder, and their experience with related disorders and traits. Impulsivity, compulsions, obsessions, generalized anxiety, panic attacks, and neuroticism have all been researched in relation with the development of alcohol use disorder and drinking behaviors. This study strived to determine the presence of these symptoms and behaviors within one’s recovery, and their effect on one’s overall sobriety. This study compared self-reported symptoms of Alcoholics Anonymous members to their current length of sobriety and past relapses. Symptoms of Attention- deficit/hyperactivity disorder, Obsessive Compulsive …

Travel-Time Disparities In Access To Proton Beam Therapy For Cancer Treatment, Todd Burus, Alexander Vanhelene, Michael Rooney, Krystle Lang Kuhs, W. Jay Christian, Christopher Mcnair, Sanjay Mishra, Arnold Paulino, Grace Smith, Steven Frank, Jeremy Warner

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

IMPORTANCE: Proton beam therapy is an emerging radiotherapy treatment for patients with cancer that may produce similar outcomes as traditional photon-based therapy for many cancers while delivering lower amounts of toxic radiation to surrounding tissue. Geographic proximity to a proton facility is a critical component of ensuring equitable access both for indicated diagnoses and ongoing clinical trials.

OBJECTIVE: To characterize the distribution of proton facilities in the US, quantify drive-time access for the population, and investigate the likelihood of long commutes for certain population subgroups.

DESIGN, SETTING, AND PARTICIPANTS: This population-based cross-sectional study analyzed travel times to proton facilities in …

Embodying The Spiral: A Critical Framework For Returning To The Body Through Dance/Movement Therapy, Lilah Van Rens

Dance/Movement Therapy Theses

Spirals are fundamental to human existence–present in natural geological forms, skeletal and muscular pathways, and developmental patterns. Characteristics of the spiral in relation to the body include: spatiotemporal nonlinearity, the embracing of polarities and dismantling of binaries, grounded curiosity, “contra-lateral connectivity” and multidimensional integration and transformation. Nonlinear and spiralic temporality have been continually embodied, recorded, and practiced transgenerationally in Black, Indigenous, and queer communities as a form of resurgence, resistance, self-expression, building community and being in the world. How can embodying the spiral be a radical resistance to systems of oppression that continually isolate and disconnect people from one another …

Boys Don't Cry: Dance/Movement Therapy As Effective Treatment For Men Who Adhere To Traditional Western Masculinity Ideology, Carter Turrell-Celente

Dance/Movement Therapy Theses

Traditional Western masculinity ideology, which is adhered to mostly by white men (Levant & Pryor, 2020, p. 12), is the dominant construct of masculinity in the United States that influences expectations of behavior among males (American Psychological Association, 2018; Levant & Richmond, 2016). Men who adhere strictly to traditional Western masculinity ideology may find their lives negatively affected by their behavior related to socialized gender norms. Seeking help for mental health challenges goes against traditional Western masculinity ideology, as does emotional expression, which makes these men especially vulnerable to the negative effects of poor mental health. Dance/movement therapy is an …