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Full-Text Articles in Medicine and Health Sciences

Impact Of Multifactorial Interventions With Medication And Lifestyle Optimization On Patients With Type 2 Diabetes: A Randomised Controlled Trial, Marwan M. El Deyarbi Nov 2024

Impact Of Multifactorial Interventions With Medication And Lifestyle Optimization On Patients With Type 2 Diabetes: A Randomised Controlled Trial, Marwan M. El Deyarbi

Thesis/ Dissertation Defenses

The incidence of diabetes is increasing worldwide, consequently increasing mortality rates due to complications such as diabetic kidney disease. Clinical evidence on the protective effect of balanced diet, exercise and medication adherence with glucose-lowering intensification therapies on the progression of diabetes is insufficient, and interventions that are most effective in slowing cardiorenal metabolic complications in patients with type 2 diabetes mellitus (T2DM), especially in the UAE population diabetes remain to be elucidated. Several studies have shown that patient-related factors and limited medication adherence in patients with chronic diseases, are associated with poor clinical outcomes, long-term complications, and increased overall disease …


Psychosocial Factors, Stress And Sleep Among Rural Appalachian Kentucky Residents With Type 2 Diabetes Mellitus, Blake Dipaola, Zoe Taylor, Eric Hennemann, Brittany L. Smalls, Philip M. Westgate, Nancy Schoenberg Oct 2024

Psychosocial Factors, Stress And Sleep Among Rural Appalachian Kentucky Residents With Type 2 Diabetes Mellitus, Blake Dipaola, Zoe Taylor, Eric Hennemann, Brittany L. Smalls, Philip M. Westgate, Nancy Schoenberg

Journal of Appalachian Health

Introduction: Rural Appalachian residents experience higher rates of most chronic diseases, including type 2 diabetes mellitus (T2DM). Stress and sleep deficiency also are common in the region.

Purpose: To better understand these associated health burdens, the relationship among these conditions and psychosocial factors—such as depressive symptoms, distress, empowerment, and social support—was examined among Appalachian residents with T2DM.

Methods: Using data collected from a community-based sample of Appalachian adults with T2DM, the study examined whether psychosocial factors were associated with perceived stress (Cohen Perceived Stress Scale) and self-reported sleep deficiency (Epworth Sleepiness Scale). Multilevel linear mixed effects regression modeling was used …


Hepatic Targets To Control Blood Glucose And Potentially Aid In The Treatment Of Diabetes, Rena A. Velissarios Oct 2024

Hepatic Targets To Control Blood Glucose And Potentially Aid In The Treatment Of Diabetes, Rena A. Velissarios

PANDION: The Osprey Journal of Research and Ideas

Maintaining glucose homeostasis is extremely important to remain in good health and prevent disease. This homeostasis is achieved via the regulation of hepatic metabolic pathways like gluconeogenesis and glycogenesis by insulin, which is expressed during high blood glucose. Insulin is responsible for facilitating the uptake of glucose into other tissues from the blood, as well as signaling whether to stimulate or slow glucose metabolism in the liver. Hyperglycemia is one of the main effects of diabetes, a disease characterized by the body’s inability to produce or respond to insulin. Without insulin, hepatic glucose output continues and blood glucose accumulates, causing …


Transcription And Post-Translational Mechanisms: Dual Regulation Of Adiponectin-Mediated Occludin Expression In Diabetes, Yanru Duan, Demin Liu, Huahui Yu, Shihan Zhang, Yihua Xia, Zhiyong Du, Yanwen Qin, Yajing Wang, Xin-Liang Ma, Huirong Liu, Yunhui Du Oct 2024

Transcription And Post-Translational Mechanisms: Dual Regulation Of Adiponectin-Mediated Occludin Expression In Diabetes, Yanru Duan, Demin Liu, Huahui Yu, Shihan Zhang, Yihua Xia, Zhiyong Du, Yanwen Qin, Yajing Wang, Xin-Liang Ma, Huirong Liu, Yunhui Du

Department of Emergency Medicine Faculty Papers

BACKGROUND: Occludin, a crucial component of tight junctions, has emerged as a promising biomarker for the diagnosis of acute ischemic disease, highlighting its significant potential in clinical applications. In the diabetes, Occludin serves as a downstream target gene intricately regulated by the adiponectin (APN) signaling pathway. However, the specific mechanism by which adiponectin regulates Occludin expression remains unclear.

METHODS AND RESULTS: Endothelial-specific Ocln knockdown reduced APN-mediated blood flow recovery after femoral artery ligation and nullified APN's protection against high-fat diet (HFD)-triggered apoptosis and angiogenesis inhibition in vivo. Mechanically, we have meticulously elucidated APN's regulatory role in Occludin expression through a …


Burden Of Diabetes Mellitus In The Medically Underserved Rio Grande Valley, John M. Gaddis, Elias Arellano, Kassandra Pulido, Tyler Torres, Dominic Chau-Zanetti, Natasha N. Quailes, Andres Suarez Parraga Sep 2024

Burden Of Diabetes Mellitus In The Medically Underserved Rio Grande Valley, John M. Gaddis, Elias Arellano, Kassandra Pulido, Tyler Torres, Dominic Chau-Zanetti, Natasha N. Quailes, Andres Suarez Parraga

School of Medicine Publications and Presentations

Introduction

Diabetes mellitus (DM) encompasses metabolic disorders characterized by elevated blood sugar. This study aimed to evaluate the prevalence and associated metrics of DM in the Rio Grande Valley (RGV), a low-income and medically underserved region in the United States, and compare these metrics to the national averages from 2012 to 2022.

Methods

A retrospective cross-sectional analysis was conducted using publicly accessible data from the Centers for Medicare and Medicaid Services (CMS). Metrics analyzed included DM prevalence, average principal cost, rates of emergency department visits, hospitalizations, screenings, and prevalence of obesity. Data from the RGV counties were compared to national …


Concurrent Challenges: New-Onset Type 2 Diabetes And Invasive Pancreatic Adenocarcinoma: A Case Report, Abhishekh Pokhrel, Alexa Lissete Zarate, Sobia Hassan Memon, Everardo Cobos Sep 2024

Concurrent Challenges: New-Onset Type 2 Diabetes And Invasive Pancreatic Adenocarcinoma: A Case Report, Abhishekh Pokhrel, Alexa Lissete Zarate, Sobia Hassan Memon, Everardo Cobos

Research Colloquium

Background: Pancreatic adenocarcinoma is a highly aggressive cancer with a five-year survival rate of about 10%, and is the third leading cause of cancer-related deaths in the United States. Approximately 53% of patients are diagnosed at stage IV, characterized by distant metastasis to common sites such as the liver and lungs. Liver metastases occur in 60-70% of metastatic cases, while lung metastases are seen in 10-15% of patients. The median survival for stage IV patients is typically around 3 to 6 months, with current treatments primarily focused on palliation. Advances in chemotherapy offer modest survival benefits, but early detection and …


Potential Involvement Of Srb1 In Type 1 Diabetes Associated Dyslipidemia: Characterizing Srb1 Antisense, Sowmya Duddu, Masami Shimizu-Albergine, Karin E. Bornfedlt Sep 2024

Potential Involvement Of Srb1 In Type 1 Diabetes Associated Dyslipidemia: Characterizing Srb1 Antisense, Sowmya Duddu, Masami Shimizu-Albergine, Karin E. Bornfedlt

Research Colloquium

Background: One of the main complications of type 1 diabetes is cardiovascular disease associated with dyslipidemia, characterized by abnormally high levels of triglyceride-rich lipoproteins in the bloodstream. This imbalance could eventually lead to complications such as atherosclerosis. Liver Scavenger Receptor Class B Type 1 (SRB1) is currently being investigated for its role in type 1 diabetes induced dyslipidemia. We aim to characterize the effects of using a liver specific SRB1 antisense (GalNAc-SRB1 ASO) in non-diabetic and diabetic mice. We hypothesize that triglyceride and cholesterol levels will increase to a greater extent in diabetic mice injected with GalNAc-SRB1 ASO than in …


Assessing The Impact Of A Comprehensive Care Model On Reducing A1c Levels Compared To Primary Care Alone: A Comprehensive Study, Hector Trejo, Lizette Ingle, Karla Soberanis Sep 2024

Assessing The Impact Of A Comprehensive Care Model On Reducing A1c Levels Compared To Primary Care Alone: A Comprehensive Study, Hector Trejo, Lizette Ingle, Karla Soberanis

Research Colloquium

Introduction: Diabetes significantly challenges the Rio Grande Valley (RGV), especially in low-income rural areas where prevalence and mortality rates are higher than in urban regions. Limited access to routine healthcare and specialists exacerbates these issues, delaying medical attention and reducing diagnostic testing and management adherence. Early diagnosis and lifestyle modification interventions show promise, but objective evaluation of these models by local organizations in the RGV. Further analysis is needed to assess their effectiveness in reducing diabetes prevalence and improving health outcomes in the RGV.

Methods: This retrospective study aims to evaluate the Comprehensive Care Model (CCM) on Improved Health Outcomes …


Anti-Diabetic Potential Of Therapeutic Medicinal Plants: A Review, Selvakumar P Aug 2024

Anti-Diabetic Potential Of Therapeutic Medicinal Plants: A Review, Selvakumar P

Palestinian Medical and Pharmaceutical Journal

Drugs for diabetes are incredibly effective, but they also have serious adverse effects. Therapeutic plants, on the other hand, might function as an alternative source of antidiabetic mediators. With an emphasis on preclinical and scientific studies, therapeutic florae with antidiabetic potential are recognized. The mutual and concentrated act of their profile of organically energetic natural complexes defines the valuable probability of each specific plant condition. Due to its all-natural origins and absence of concomitant side effects, herbal medicine has become exponentially more appealing in recent years, gaining fame in both emerging and developed nations. A systematic education program was put …


Paracrine Factors Regulate Glucagon Trafficking Through The Stmn2-Mediated Lysosomal Network, Nelson Chang Jul 2024

Paracrine Factors Regulate Glucagon Trafficking Through The Stmn2-Mediated Lysosomal Network, Nelson Chang

Electronic Thesis and Dissertation Repository

In diabetes, excess glucagon secretion and insulin deficiency contribute to disease progression and hyperglycemia. Understanding the intracellular trafficking of glucagon in alpha cells can reveal potential therapeutic targets to alleviate hyperglycemia. Stathmin-2 (Stmn2) was previously found in the secretory granules of αTC1-6 cells and was hypothesized to direct glucagon to lysosomes for degradation. My work aims to investigate whether paracrine inhibition of glucagon secretion operates through the Stmn2-mediated lysosomal pathway.

I manipulated Stmn2 levels and applied paracrine treatment to observe glucagon and lysosome distribution using microscopy. I found that Stmn2 was essential in mediating paracrine redistribution of glucagon and lysosomes. …


Prevalence Of Dermatological Conditions Among Patients With Diabetic Neuropathy In The Rio Grande Valley: A Retrospective Analysis, Jared Hensley, Blake Martin, Chloe C. Harris, Kelsey Baker Jul 2024

Prevalence Of Dermatological Conditions Among Patients With Diabetic Neuropathy In The Rio Grande Valley: A Retrospective Analysis, Jared Hensley, Blake Martin, Chloe C. Harris, Kelsey Baker

School of Medicine Publications and Presentations

Background: Diabetic neuropathy, a common complication of diabetes, predisposes patients to various secondary health issues, including dermatological conditions. This study investigates the prevalence and types of skin conditions (ICD-10 codes L00-L99) among patients with diabetic neuropathy within a South Texas population, aiming to uncover potential correlations and their implications in patient management.

Method: This research involved a detailed retrospective review of the UT Health RGV medical database over the past five years, focusing on patients diagnosed with diabetic neuropathy (Type 1: E10.40 to E10.49, E10.610, E10.618; Type 2: E11.40 to E11.49, E11.610, E11.618) and any associated L-series skin conditions. Efforts …


Development And Validation Of A Measure For Seeking Health Information In The Diabetes Online Community: Mixed Methods Study, Allyson S. Hughes, Sarah Beach, Spruhaa Vasistha, Nazanin M. Heydarian, Osvaldo F. Morera Jul 2024

Development And Validation Of A Measure For Seeking Health Information In The Diabetes Online Community: Mixed Methods Study, Allyson S. Hughes, Sarah Beach, Spruhaa Vasistha, Nazanin M. Heydarian, Osvaldo F. Morera

School of Social Work Faculty Publications and Presentations

Background

Individuals with chronic diseases often search for health information online. The Diabetes Online Community (DOC) is an active community with members who exchange health information; however, few studies have examined health information brokering in the DOC.

Objective

The aim of this study was to develop and validate the Attitudes Toward Seeking Health Information Online (ATSHIO) scale in a sample of adults with type 1 diabetes (T1D).

Methods

People with T1D were recruited through the DOC, specifically Facebook and Twitter. They were provided with a Qualtrics link to complete the survey. This was a mixed methods study that used thematic …


An Expanded Chronic Care Management Approach To Multiple Chronic Conditions In Hispanics Using Community Health Workers As Community Extenders In The Rio Grande Valley Of Texas, Juliana Z. Lopez, Minjae Lee, Soo K. Park, Maria E. Zolezzi, Lisa A. Mitchell-Bennett, Paul Gerardo Yeh, Lubeth Perez, Natalia I. Heredia, David D. Mcpherson, Joseph B. Mccormick, Belinda M. Reininger Jul 2024

An Expanded Chronic Care Management Approach To Multiple Chronic Conditions In Hispanics Using Community Health Workers As Community Extenders In The Rio Grande Valley Of Texas, Juliana Z. Lopez, Minjae Lee, Soo K. Park, Maria E. Zolezzi, Lisa A. Mitchell-Bennett, Paul Gerardo Yeh, Lubeth Perez, Natalia I. Heredia, David D. Mcpherson, Joseph B. Mccormick, Belinda M. Reininger

Health & Biomedical Sciences Faculty Publications and Presentations

Introduction

The synergistic negative effects of type 2 diabetes (T2DM) and hypertension increases all-cause mortality and the medical complexity of management, which disproportionately impact Hispanics who face barriers to healthcare access. The Salud y Vida intervention was delivered to Hispanic adults living along the Texas-Mexico Border with comorbid poorly controlled T2DM and hypertension. The Salud y Vida multicomponent intervention incorporated community health workers (CHWs) into an expanded chronic care management model to deliver home-based follow-up visits and provided community-based diabetes self-management education.

Methods

We conducted multivariable longitudinal analysis to examine the longitudinal intervention effect on reducing systolic and diastolic blood …


Awareness Of The Diabetic Population Towards Diabetic Complications: A Descriptive Cross-Sectional Study, Hafiza Muriam Ghani, Layba Marrium, Maryam Aftab, Rikza Khalid Jun 2024

Awareness Of The Diabetic Population Towards Diabetic Complications: A Descriptive Cross-Sectional Study, Hafiza Muriam Ghani, Layba Marrium, Maryam Aftab, Rikza Khalid

Internet Journal of Allied Health Sciences and Practice

Background: Diabetes (DM) is a complex disease that affects more than 170 million people worldwide. Despite its knowledge, compliance with medications, and following a diet plan, diabetic patients are at risk of many chronic complications affecting different organ systems, which deteriorates health of the population and increases health care costs. Awareness of diabetic complications at the community level is important to reduce diabetes-related morbidity, mortality and ultimately health care cost. Purpose: The purpose of this study is two-fold: 1) To assess the level of awareness of diabetic complications in diabetic patients, and 2) To identify the prevalence of the most …


The Glucosylamine Oxidation Pathway Of Vitamin C Recycling, James M. Hempe, Daniel S. Hsia, Arthur Hagar, Larry Byers Jun 2024

The Glucosylamine Oxidation Pathway Of Vitamin C Recycling, James M. Hempe, Daniel S. Hsia, Arthur Hagar, Larry Byers

School of Medicine Faculty Publications

The proposed glucosylamine oxidation pathway (GOP) is a two-step, intraerythrocyte, thermodynamically favorable nonenzymatic reaction that first binds glucose to the N-terminal valine of beta globin (βVal1) to form a closed-chain glucosylamine that can spontaneously reduce oxidized vitamin C to its antioxidant form. This review summarizes analytical, biochemical and clinical research supporting the existence of the GOP and the surprising hypothesis that βVal1 glucosylamine is a reducing agent that works cooperatively with reduced glutathione to dynamically regulate vitamin C recycling during naturally occurring periods of transiently or chronically elevated blood glucose and oxidant production. Rationale for the existence of the GOP …


Effects Of Exercise Or Metformin On Myokine Concentrations In Patients With Breast And Colorectal Cancer: A Phase Ii Multi-Centre Factorial Randomized Trial, Justin C. Brown, Guillaume Spielmann, Shengping Yang, Stephanie L.E. Compton, Lee W. Jones, Melinda L. Irwin, Jennifer A. Ligibel, Jeffrey A. Meyerhardt Jun 2024

Effects Of Exercise Or Metformin On Myokine Concentrations In Patients With Breast And Colorectal Cancer: A Phase Ii Multi-Centre Factorial Randomized Trial, Justin C. Brown, Guillaume Spielmann, Shengping Yang, Stephanie L.E. Compton, Lee W. Jones, Melinda L. Irwin, Jennifer A. Ligibel, Jeffrey A. Meyerhardt

School of Medicine Faculty Publications

Background: Physical activity and metformin pharmacotherapy are associated with improved clinical outcomes in breast and colorectal cancer survivors. Myokines are cytokines secreted from skeletal muscle that may mediate these associations. Methods: This hypothesis-generating analysis used biospecimens collected from a multi-centre 2 × 2 factorial randomized design of 116 patients with stage I–III breast and colorectal cancer who were randomized to 12 weeks of (1) aerobic exercise (moderate intensity titrated to 220 min/week); (2) metformin (850 mg daily for 2 weeks and then titrated to 850 mg twice per day); (3) aerobic exercise and metformin; or (4) control. Fourteen myokines were …


Digital Gaming And Exercise Among Youth With Type 1 Diabetes: Cross-Sectional Analysis Of Data From The Type 1 Diabetes Exercise Initiative Pediatric Study., Susana R. Patton, Robin L. Gal, Simon Bergford, Peter Calhoun, Mark A. Clements, Jennifer L. Sherr, Michael C. Riddell Jun 2024

Digital Gaming And Exercise Among Youth With Type 1 Diabetes: Cross-Sectional Analysis Of Data From The Type 1 Diabetes Exercise Initiative Pediatric Study., Susana R. Patton, Robin L. Gal, Simon Bergford, Peter Calhoun, Mark A. Clements, Jennifer L. Sherr, Michael C. Riddell

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: Regular physical activity and exercise are fundamental components of a healthy lifestyle for youth living with type 1 diabetes (T1D). Yet, few youth living with T1D achieve the daily minimum recommended levels of physical activity. For all youth, regardless of their disease status, minutes of physical activity compete with other daily activities, including digital gaming. There is an emerging area of research exploring whether digital games could be displacing other physical activities and exercise among youth, though, to date, no studies have examined this question in the context of youth living with T1D.

OBJECTIVE: We examined characteristics of digital …


Cost Variation Analysis Of Oral Hypoglycemic Drugs In The Egyptian Market, George G. Abdelmessih, Aya M. Abdelmagid, Samar F. Farid Jun 2024

Cost Variation Analysis Of Oral Hypoglycemic Drugs In The Egyptian Market, George G. Abdelmessih, Aya M. Abdelmagid, Samar F. Farid

Bulletin of Faculty of Pharmacy Cairo University

Introduction: Type II diabetes mellitus is a lifelong condition requiring lifelong medication. This study aims to analyze the cost variation of the oral hypoglycemic drugs in the Egyptian pharmaceutical market.

Methodology: Egyptian drug database of the Egyptian Drug Authority was used to get the official prices of drugs in the Egyptian pharmaceutical market analyzed in this study. The cost ratio and the percentage cost variation were calculated. The price was documented using unit dose of 1 tablet per EGP.

Results: Out of 15 oral hypoglycemic drugs in the Egyptian market at closing 2022 (9 monotherapy and 6 combination therapy) of …


High All-Cause Mortality And Increasing Proportion Of Older Adults With Tuberculosis In Texas, 2008–2020, Belinda A. Medrano, Miryoung Lee, Gretchen L. Gemeinhardt, Lana Yamba, Blanca I. Restrepo May 2024

High All-Cause Mortality And Increasing Proportion Of Older Adults With Tuberculosis In Texas, 2008–2020, Belinda A. Medrano, Miryoung Lee, Gretchen L. Gemeinhardt, Lana Yamba, Blanca I. Restrepo

School of Medicine Publications and Presentations

Pulmonary tuberculosis (PTB) elimination efforts must consider the global growth of the ageing population. Here we used TB surveillance data from Texas, United States (2008–2020; total n = 10656) to identify unique characteristics and outcomes in older adults (OA, ≥65 years) with PTB, compared to young adults (YA, 18–39 years) or middle-aged adults (40–64 years). We found that the proportion of OA with PTB increased from 15% in 2008 to 24% in 2020 (trend p < 0.05). Diabetes was highly prevalent in OA (32%) but not associated with adverse outcomes. Death was 13-fold higher in OA compared to YA and was 7% at the time of diagnosis which suggests diagnostic delays. However, once TB was suspected, we found no differences in culture, smear, or nucleic acid detection of mycobacteria (although less lung cavitations) in OA. During treatment, OA had less drug-resistant TB, few adverse reactions and adhered with TB treatment. We recommend training healthcare workers to ‘think TB’ in OA, for prompt treatment initiation to diminish deaths. Furthermore, OA should be added as a priority group to the latent TB treatment guidelines by the World Health Organization, to prevent TB disease in this highly vulnerable group.


Rural And Urban Differences In Eye Care Among Persons With Diabetes Enrolled In Original Medicare - Georgia, 2019, Pathya Kunthy, Grace M. Perry, Lauren Ball May 2024

Rural And Urban Differences In Eye Care Among Persons With Diabetes Enrolled In Original Medicare - Georgia, 2019, Pathya Kunthy, Grace M. Perry, Lauren Ball

Research Day

No abstract provided.


Mortality Of Patients Hospitalized By Covid-19 In Mexico, Systematic Review, Ana Portocarrerero Granados, Lya A Castro Rodriguez, Antonio Sandoval-Cabrera, María Del Socorro Romero Figueroa May 2024

Mortality Of Patients Hospitalized By Covid-19 In Mexico, Systematic Review, Ana Portocarrerero Granados, Lya A Castro Rodriguez, Antonio Sandoval-Cabrera, María Del Socorro Romero Figueroa

Revista de la Facultad de Medicina Humana

Introduction: Since the start of the pandemic, Mexico was one of the countries with the highest mortality rates from COVID 19. Objective: To determine if type 2 diabetes mellitus, arterial hypertension, and obesity increase mortality in patients diagnosed with COVID-19 who required hospitalization in Mexico. Methods: Systematic review in Pubmed MeSH, Web of Science, Lilas, Scielo, and Google Scholar with the terms MeSH COVID-19, SARS-COV2, Coronavirus, and Mexico for the years 2020 and 2021, in English or Spanish. Two reviewers selected the studies, two additional reviewers participated in the analysis of the studies. Results: Seventy three studies carried out in …


Evaluation Of Clinical Aspects Related To Lower Limb Amputation Among Individuals Living With Type 2 Diabetes Mellitus In Mexico, Julio Cesar Parra Acosta, Laura Ávila Jiménez, Antonio Monroy Noyola, Diana Lizbeth Gómez Galicia, Daniel Álvarez Escobedo, Cairo Toledano Jaimes May 2024

Evaluation Of Clinical Aspects Related To Lower Limb Amputation Among Individuals Living With Type 2 Diabetes Mellitus In Mexico, Julio Cesar Parra Acosta, Laura Ávila Jiménez, Antonio Monroy Noyola, Diana Lizbeth Gómez Galicia, Daniel Álvarez Escobedo, Cairo Toledano Jaimes

Revista de la Facultad de Medicina Humana

Introduction: Diabetes continues to be one of the leading causes of disability and death in the global population. It is estimated that approximately 25% of people living with diabetes will develop an ulcer on one of their lower pelvic limbs. Objective: The present study evaluates the clinical aspects related to lower pelvic limb amputation in a cohort of patients with diabetes mellitus. Materials and Methods: A retrospective cross-sectional study was conducted consisting in a review of the total census of patients with type 2 diabetes. They received medical attention in the setting of the study in the period January-May 2022. …


Oncology Infusion Center Hyperglycemia Protocol, Franklin L. Thelmo, Do Jr., Eric J. Shiffrin, Md, Rose Dimarco, Pharmd, Bcps, Bcop, Emily Brand, Pharmd, Daniel Lin, Md May 2024

Oncology Infusion Center Hyperglycemia Protocol, Franklin L. Thelmo, Do Jr., Eric J. Shiffrin, Md, Rose Dimarco, Pharmd, Bcps, Bcop, Emily Brand, Pharmd, Daniel Lin, Md

Health Equity and Quality Improvement (HEQI) Summit

Background

  • Problem: Patients receiving chemotherapy for their cancer are often overwhelmed with the stresses of their new diagnoses and other coexistent medical issues may be forgotten or ignored. In the event dysglycemia or diabetes appears during the course of chemotherapy it may difficult for these patients to obtain care in a timely fashion and early literature suggests that dysglycemia may decrease the efficacy of chemotherapy
  • Aim: Our goal was a protocol designed to ensure adequate euglycemia in patients at the Oncology Infusion Center (OIC) to eliminate insulin treatment guesswork for hyperglycemia, allow timely care with endocrinology specialists, and create a …


Pharmacist-Assisted Insulin Titration In Primary Care To Improve Diabetes Outcomes, Megana Murugesh, Md, Alisha Goyal, Michael Kelly, Pharmd, Emily Scopelliti, Pharmd, Barbara Simon, Md, Aparna Sarin, Md, Mph May 2024

Pharmacist-Assisted Insulin Titration In Primary Care To Improve Diabetes Outcomes, Megana Murugesh, Md, Alisha Goyal, Michael Kelly, Pharmd, Emily Scopelliti, Pharmd, Barbara Simon, Md, Aparna Sarin, Md, Mph

Health Equity and Quality Improvement (HEQI) Summit

Background

Problem Statement: Approximately, 90% of patients with Type 2 Diabetes (T2DM) are treated by primary care providers (PCPs) and with a growing aging population, and a shrinking primary care workforce, the demand for PCPs to provide care to diabetics is only expected to further worsen.

Despite novel therapies in T2DM, insulin remains a mainstay in treatment. Titrating insulin is a tedious and time-consuming task, requiring frequent follow-ups and lengthy conversations, increasing the burden of care on PCPs.

Project AIM:

  1. Assess efficacy of pharmacy–assisted insulin titration in T2DM in achieving glycemic control by monitoring blood glucose and A1c changes
  2. Evaluate …


Early Non-Invasive Monitoring Of Fatty Liver Disease Using Emr Software, Franklin L. Thelmo, Do Jr., Eric J. Shiffrin, Md May 2024

Early Non-Invasive Monitoring Of Fatty Liver Disease Using Emr Software, Franklin L. Thelmo, Do Jr., Eric J. Shiffrin, Md

Health Equity and Quality Improvement (HEQI) Summit

Background

  • Problem: Metabolic Dysfunction-Associated Fatty Liver Disease (MAFLD) and Metabolic Dysfunction-Associated Steatohepatitis (MASH) are liver diseases that have rapidly increased in the population over the last few years and are becoming an evercommon cause of liver failure and the need for liver transplant. Disease presence long predates concerning symptoms and many individuals will not be made aware until after the diseased has progressed in severity. Earlier intervention is often inhibited due to the need of invasive biopsy or specific lab testing not easily available leading to significant underdiagnosis of patients with early disease
  • Project AIM: We sought to add a …


Pricks And Pills, Anna A. Charles May 2024

Pricks And Pills, Anna A. Charles

Theses and Dissertations

"Pricks and Pills" is a collection of audio pieces designed for an online platform where individuals with diabetes can listen to and find emotional support from others who share their experiences. This audio project provides an intimate look into the lives of people navigating the challenges of diabetes. Through heartfelt interviews with individuals and their families, the podcast highlights their journeys, showcasing both their struggles and triumphs.


Exploring Geriatric Self Management Of Type 2 Dm: A Systematic Review, Ahmed Gawash, David F. Lo, Kunal P. Shah, Jasmine Emanuel, Brandon Goodwin, Don D. Shamilov, Gaurav Kumar, Nathan Jean, Christian P. White May 2024

Exploring Geriatric Self Management Of Type 2 Dm: A Systematic Review, Ahmed Gawash, David F. Lo, Kunal P. Shah, Jasmine Emanuel, Brandon Goodwin, Don D. Shamilov, Gaurav Kumar, Nathan Jean, Christian P. White

Rowan-Virtua Research Day

This review explores diabetic self-management in geriatric individuals, focusing on positive attitudes and support from family/friends as crucial for self-care optimization. A comprehensive search in health databases was conducted, which involved screening 248 participants across eight qualitative research studies. Themes emphasizing the importance of listening to one’s body, acknowledging hidden issues, and recognizing the impact of various factors on diabetes self-care were established. A holistic approach to self management, emphasizing the significance of positive attitudes, cultural sensitivity, and individual values in healthcare practices is recommended. Embracing cultural diversity and addressing barriers can enhance self-management and quality of life for geriatric …


Diabetes Health Education For South Jersey Communities, Heaven Chu, Sarah Tamous, Ashhabal Kavvi, Amin Khan May 2024

Diabetes Health Education For South Jersey Communities, Heaven Chu, Sarah Tamous, Ashhabal Kavvi, Amin Khan

Rowan-Virtua Research Day

Diabetes is a chronic health condition that hinders the body’s metabolic process using insulin to maintain glycemic homeostasis. It is prevalent worldwide, with about 10% of the global adult population affected. Socio-economic and cultural factors and determinants make diabetes and diabetes management more of a health risk for certain populations rather than others. The prevalence of diabetes in the United States is higher than the global average and the risk factors disproportionately affect disadvantaged communities.

This study was designed to investigate health disparities in diabetes among a diverse population sample. The study included researching the disparities of diabetes patients in …


Impact Of Diabetic Education On Reducing Hospital Readmission Rates: A Literature Review Of Adults With Diabetes, Frank Camarda May 2024

Impact Of Diabetic Education On Reducing Hospital Readmission Rates: A Literature Review Of Adults With Diabetes, Frank Camarda

Rowan-Virtua Research Day

According to 2018 data from the Diabetes Institute Foundation, adults in the U.S. diagnosed with diabetes accounted for 17 million emergency department visits. The readmission rate for patients with diabetes far exceeds the general readmission rates for hospitalized patients. While there is recognition of the need for diabetic education to reduce hospital readmissions, optimizing long-term self-management of diabetics remains a focus of ongoing research.


Effects Of Chronic Diabetes And Attentional Focus On Performance And Learning Of A Novel Stabilometer Balance Task, Rebeca Carolina Armagnac Gonzalez, Yinny H. Lee, Alicia Marie Letkiewicz, Meiko Nagano Mamauag May 2024

Effects Of Chronic Diabetes And Attentional Focus On Performance And Learning Of A Novel Stabilometer Balance Task, Rebeca Carolina Armagnac Gonzalez, Yinny H. Lee, Alicia Marie Letkiewicz, Meiko Nagano Mamauag

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background and Purpose: Chronic diabetes is a prevalent systemic disease that impairs physical functioning and often leads to increased risk of falls. Adopting an external focus of attention during motor skill practice has been shown to improve learning outcomes, however, it has not been examined in this population. We examined how attentional focus instructions (internal vs. external) affect balance performance and learning in older adults with and without diabetes.

Methods: Fifty-three older adults (27 with diabetes, 63.7±7.0 years) participated in the randomized, pre-post intervention study. The balance training involved 50 practice trials of a stabilometer task that was novel to …