Medicine and Health Sciences Commons^™

Assessment Of Hind Limb Muscle Activity After Stair-Climbing In A Dog Using 18f-Fdg Pet/Ct: A Case Report, Heesoo Ahn, Seungho Lee, Yoocheol Shin, Byoungho An, Dongwook Kim, Byeong-Teck Kang, Gonhyung Kim

The Thai Journal of Veterinary Medicine

Accurate assessment of functional muscle activation is important for planning rehabilitation exercises in canine patients. Conventional methods, such as electromyography and gait analysis, have limitations in evaluating deep muscles and providing a comprehensive assessment of muscle activity. This case study used ¹⁸F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) to assess hind limb muscle activity in a dog after stair-climbing exercise. A 4-year-old castrated male Beagle underwent 1 h of stair-climbing exercise followed by FDG PET/CT scanning. Increased FDG uptake was observed in multiple hind limb muscles, particularly the gluteus medius and quadratus femoris muscles. The quadratus femoris, a deep …

A Combination Of Hyoscyamine And Theophylline For Treatment Of Sick Sinus Syndrome In A Dog, Uraiwan Saengkieo, Arisara Kiatsilapanan, Suwanakiet Sawangkoon

The Thai Journal of Veterinary Medicine

A-12-year-old female West Highland White Terrier presented with a history of cardiac syncope. Physical examination revealed bradycardia. Sick sinus syndrome (SSS) was diagnosed with electrocardiography and 24-hour Holter monitoring. However, the owner made the decision to receive the pharmacological therapy. Therefore, a combination of hyoscyamine sulfate and theophylline was prescribed. Following two adjustments of drug dosage and frequency within a year, the total number of heartbeats increased from 58,091 to 73,686 beats, and the mean heart rate increased from 44 to 59 bpm. After the treatment, the dog became stable and no syncopal episodes were detected, despite the presence of …

Sertoli Cell Tumor In A Boar: Pathological And Immunohistochemical Comparison With Canine Cases, Anurak Tibboo, Hataitip Changchum, Nuttiya Saengrueng, Panvard Unjai, Natchanon Dumniem, Kasem Rattanapinyopituk, Komkrich Teankum

The Thai Journal of Veterinary Medicine

Sertoli cell tumors (SCTs) are sex cord–stromal tumors of the testis that are common in dogs but rare in boars. This study characterized the pathological features of an SCT in a boar and compared its immunohistochemical profile with that of canine SCTs. Testicular tissues from boars (SCT, n = 1; normal testes, n = 2) and dogs (SCT, n = 3; normal testes, n = 5) were evaluated by histopathology and immunohistochemistry for proliferating cell nuclear antigen (PCNA), vimentin, and cytokeratin. Gross examination revealed a solitary, well-circumscribed nodule in the left testis of the boar, accompanied by severe bilateral testicular …

Effectiveness Of An Integrated Activity-Based And Tele-Monitoring Intervention On Mental Health Literacy And Resilience Among Urban Older Adults In Thailand: A Quasi-Experimental Study, Khunatpakorn Makkabphalanon, Pramote Thangkratok, Jutamast Wongjan, Natchaya Palacheewa

Journal of Health Research

Background: Mental health problems among older adults are a growing public health concern, particularly in urban areas. Mental health literacy can enhance problem recognition, self-help, and help-seeking. This study examined changes in mental health literacy and resilience among urban older adults following an integrated activity-based and tele-monitoring intervention.

Methods: A one-group quasi-experimental repeated-measures study was conducted among 30 adults aged 60 years and older in urban communities in Thailand. Participants received a structured 3-hour activity-based mental health literacy intervention followed by 1 month of tele-monitoring support. Data were collected at baseline, immediately after the intervention, and at 1-month follow-up. Changes …

Presumptive Feline Infectious Peritonitis-Associated Uveitis With Posterior Segment Mass-Like Lesions On Ultrasonography, Hyun-Wook Kim, Danbee Kwon, Joon Young Kim

The Thai Journal of Veterinary Medicine

5-year-old neutered male domestic shorthair cat was presented with unilateral anterior uveitis and ocular pain in the left eye without systemic signs. Ophthalmic examination revealed a superficial corneal ulcer, keratic precipitates, and aqueous flare. Ocular ultrasonography identified ciliary body thickening and a nodular mass-like lesion posterior to the ciliary body. Despite systemic corticosteroid treatment after corneal ulcer healing, no clinical improvement was observed. Computed tomography revealed contrast-enhancing thickening of the ciliary body and uveoscleral region. Enucleation and histopathology demonstrated pyogranulomatous inflammation without evidence of neoplasia or detectable infectious organisms. Immunohistochemistry for feline coronavirus antigen was not performed at that time. …

Expression Of Follicle Stimulating And Luteinizing Hormone Receptors In Porcine Testes After Timing The First Vaccination For Immunocastration, Sayamon Srisuwatanasagul, Rungrueang Yodsheewan, Amornthep Archawakulathep, Suvaluk Seesupa, Kongkiat Srisuwatanasagul, Atthaporn Roongsitthichai, Siriluck Juntautsa

The Thai Journal of Veterinary Medicine

This study aimed to examine the expression of follicle stimulating hormone receptor (FSHR) and luteinizing hormone receptor (LHR) in the testes of male fattening pigs based on the timing of the first immunocastration dose. A total of 24 male pigs were randomly assigned to 3 groups: C (n=8) consisted of only intact pigs, T1 (n=8) contained those immunocastrated at 15 and 19 weeks of age, and T2 (n=8) was composed of those immunocastrated at 9 and 19 weeks of age. The expression of FSHR and LHR was evaluated using H-score from immunohistochemistry and protein band intensity from Western blotting. Immunohistochemistry …

Efficacy Of A Mouthwash Containing Standardized Centella Asiatica Extract (Eca 233) In Patients With Gingivitis: A Randomized Double-Blind Placebo-Controlled Trial, Alisa Awapark, Wanchai Chongcharoen, Mayuree H. Tantisira, Nattapon Rotpenpian

The Thai Journal of Pharmaceutical Sciences

Background: Gingivitis is the earliest and most reversible stage of periodontal disease, characterized by inflammation of the gingiva caused by the accumulation of plaque. In addition to removing plaque, mouthwash containing antiseptic or anti-inflammatory could be used as an adjunct therapy.
Objectives: The objective of this study is to evaluate the efficacy of a 0.10% standardized Centella asiatica extract (ECa 233) mouthwash compared to 0.12% chlorhexidine and placebo mouthwashes in individuals with gingivitis.
Materials and Methods: A randomized, double-blind, placebo-controlled clinical trial was conducted in 75 patients assigned equally to ECa 233, chlorhexidine, or placebo groups. Participants used the assigned …

Cost Analysis Of Integrated Genderaffirming And Sexual Health Services For Transgender Women In Thailand: Evidence From The Tangerine Clinic, Braprut Sawatwipachai, Kunncadah Anuwong, Nittaya Phanuphak, Rena Janamnuaysook, Kritima Samitpol, Sujin Nitadpakorn

The Thai Journal of Pharmaceutical Sciences

Background: Transgender women experience a disproportionate burden of human immunodeficiency virus (HIV) globally and in Thailand. Integrating gender-affirming care into sexual health services may improve uptake of HIV and sexually transmitted infections (STIs) testing, treatment, and prevention. Cost data are essential to inform program planning and policy decisions regarding inclusion of such services within Thailand’s Universal Health Coverage (UHC) system.
Objectives: To estimate the full and unit costs of trans-led, integrated gender-affirming and sexual health services along the HIV care cascade.
Methods: Costs of Tangerine Clinic services in 2021 were assessed from the provider perspective, using standard and activity-based costing …

Surgical And Transcatheter Pulmonary Valve Replacement In Patients With Congenital Heart Disease, Who Have A History Of Right Ventricular Outflow Tract Remodeling, Indonesia: A Model-Based Economic Evaluation, Andi Nurul Annisa, Puree Anantachoti, Radityo Prakoso, Dafsah A. Juzar, Osot Nerapusee

The Thai Journal of Pharmaceutical Sciences

Background: Patients with congenital heart disease who have previously undergone right ventricular outflow tract (RVOT) surgery frequently require repeat valve replacement later in life. While transcatheter pulmonary valve replacement (TPVR) offers less invasive reintervention compared with surgery, its high device cost raises concerns about affordability under Indonesia’s National Health Insurance Program (Jaminan Kesehatan Nasional).
Objectives: To compare the cost-effectiveness of surgical pulmonary valve replacement (SPVR) versus TPVR in post-RVOT surgery patients, and to estimate the TPVR price threshold for cost-effectiveness from a societal perspective.
Methods: A Markov model simulated a hypothetical cohort of 15-year-old patients with prior RVOT surgery over …

Comparative Potency Testing Of Diphtheria Toxoid In Guinea Pigs And Mice For In-House Diphtheria-Tetanus-Pertussis And Diphtheria-Tetanus Vaccines, Wanlop Leeden, Supanee Ummalukacholk, Orawin Mangkhaladul, Eakachai Prompetchara

The Thai Journal of Pharmaceutical Sciences

Background: Diphtheria remains endemic in parts of Thailand and continues to threaten unvaccinated populations. To strengthen vaccine self-sufficiency, the Government Pharmaceutical Organization has developed in-house diphtheria–tetanus–pertussis (DTP) and diphtheria– tetanus (dT) vaccines. Potency testing of diphtheria toxoid is traditionally performed in guinea pigs; however, limitations in animal availability, cost, and logistics have prompted evaluation of alternative models.
Objectives: To compare diphtheria toxoid potency estimates of in-houseproduced DTP and dT vaccines using guinea pigs and mice, followed by a Vero cell-based toxin neutralization assay, and to assess the suitability of mice as an alternative model for potency testing.
Materials and Methods: …

Development Of Micellar Sprays Containing Rhinacanthus Nasutus Extract For Dandruff Management, Suwipa Ungphaiboon Associate Professor, Sutasinee Ardhanwanich, Ketsuda Wongsuwan, Salwa Yanya, Nattanit Aekwattanaphol

The Thai Journal of Pharmaceutical Sciences

Background: Dandruff is a common scalp disorder associated with altered sebum secretion and microbial imbalance, particularly between Cutibacterium and Staphylococcus, which correlates with disease severity.
Objectives: This study aimed to develop and optimize a multifunctional leave-on hair and scalp spray with anti-dandruff, nourishing, and protective properties.
Materials and Methods: Micelles containing Rhinacanthus nasutus extract were prepared using eco-friendly methods, including film hydration and direct solubilization. The formulations were optimized and evaluated for physicochemical properties, drug release, and antibacterial activity.
Results: The optimized micellar spray (BP), prepared through direct solubilization in citrate buffer, exhibited a mean particle size of 192.45 …

Modified Etoposide Loaded Graphene Oxide Nanoparticles: In-Depth Physical And Biological Evaluation For Lung Cancer Treatment, Umesh Kumar Atneriya, Jitendra Sainy

The Thai Journal of Pharmaceutical Sciences

Background: Lung cancer is approximately 25% of all death cases in any cancer and the death beats the number of deaths reported by colorectal cancer, breast cancer, and prostate cancer combined.
Objectives: This present study was carried out with an objective to investigate the possibility of graphitic carbon toward making a multifunctional anti-lung cancer nano-platform targeting etoposide (ETS) as a model drug.
Materials and Methods: First, the synthesis of graphene oxide (GO) was made by the Hummer method based on graphite flakes and further modified with folic acid (FA) and polyethylene glycol to make FA/GO/ETS. The formation of FA/GO/ETS was …

Prevalence And Characteristics Of Feline Pleural Effusion In Khon Kaen, Thailand: A 2024–2025 Study, Karn Yongvanit, Naruepon Kampa

The Thai Journal of Veterinary Medicine

Pleural effusion (PE) is a life-threatening condition in cats that can cause severe respiratory compromise. Identification of the underlying etiology is essential for prognosis and treatment planning. This study investigated the prevalence and characteristics of diseases associated with feline pleural effusion in northeastern Thailand. Medical records of cats diagnosed with pleural effusion at the Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Khon Kaen University, Thailand, between January 2024 and January 2025 were retrospectively reviewed. Cases lacking a complete diagnostic workup were excluded. Diagnoses were confirmed using cytology or histopathology for neoplasia, echocardiography for heart disease, polymerase chain reaction (PCR) for …

From Readiness To Transformation: The Mediating Role Of Digital Maturity In Linking Ai Readiness To Organizational Change In Hospitals, Muhammad Ryan Adi Putra, Giovanni Reynaldo, Dewi Sri Surya Wuisan

Journal of Health Research

Background: Organizational readiness is essential for AI-enabled digital transformation as healthcare organizations increasingly integrate artificial intelligence (AI). However, empirical evidence regarding the relationship between AI readiness and organizational change, the mediating role of digital maturity, remains limited in healthcare settings. This study investigated the mediating role of digital maturity in the relationship between AI readiness and organizational change.

Methods: This cross-sectional study involved 300 healthcare professionals from two Indonesian hospitals: Persahabatan Hospital (n = 165) and St. Carolus Hospital (n = 135). Data were collected using a questionnaire and analyzed through Partial Least Squares Structural Equation Modeling (PLS-SEM) to assess …

Identifying Pyle's Metaphyseal Dysplasia – An Incidental Finding Of Skeletal Pathology On A Dental Checkup, Shruthi Parthasarathy, Amudhan Azhagan, Arthisri Anandhi Sekar, Poongodi V, Ram Shankar

Chulalongkorn Medical Journal

Introduction:

Pyle's disease, also known as familial metaphyseal dysplasia, is a rare autosomal recessive genetic disorder that primarily affects the skeletal system, particularly in children and adolescents. Characterized by distinctive radiographic features such as Erlenmeyer flask deformity and metaphyseal widening, Pyle's disease often goes underdiagnosed due to its mild clinical manifestations.

Case report:

This case report details a 15-year-old female patient presenting with retained milk teeth and unerupted permanent teeth, alongside notable skeletal abnormalities including genu valgum and kyphosis. Clinical and radiographic evaluations revealed significant dental anomalies, including multiple impacted permanent teeth and mild dysmorphic facial features. Although genetic testing …

Beyond Lipid-Lowering: Pleiotropic Effects Of Statins In Inflammation, Coagulation, And Cell Proliferation – Mechanisms And Clinical Implications, Kasidid Lawongsa, Yutthana Pansuwan, Supanut Kumjan

Chulalongkorn Medical Journal

Statins are widely used lipid-lowering agents that significantly reduce cardiovascular morbidity and mortality through inhibition of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. Beyond their cholesterol-lowering properties, increasing evidence demonstrates that statins exert several pleiotropic effects independent of lipid reduction. These effects include anti-inflammatory, anti-thrombotic, and anti-proliferative actions mediated primarily through inhibition of the mevalonate pathway and downstream signaling molecules such as Rho, Rac, and Ras. Experimental and clinical studies have suggested potential benefits of statins in various non-cardiovascular conditions, including autoimmune diseases, venous thromboembolism, sepsis-associated coagulopathy, and certain malignancies. In addition, pharmacoepidemiologic studies have provided insights into the real-world effects and …

Evaluation Of Mdm2 Mrna Expression According To Clinicopathological Characteristics In Oral Squamous Cell Carcinoma (Oscc) Patients, Tirta Wardana

Chulalongkorn Medical Journal

Background: The murine double minute 2 (MDM2) gene encodes an E3 ubiquitin ligase that targets p53 for degradation, thereby influencing the pathogenesis of oral squamous cell carcinoma (OSCC).

Objective. The present study investigates MDM2 mRNA expression and its association with clinical and pathological characteristics in OSCC patients.

Methods: We conducted an observational-analytical study using a cross-sectional design. The study involved 39 OSCC patients. RNA extraction, cDNA synthesis, and quantitative PCR (qPCR) were performed. We quantified relative MDM2 mRNA expression using the Livak method (2-ΔΔCT) and GenEX MultiD software version 6.0. Statistical significance was assessed using independent t-tests.

Results: Although no …

Factors Associated With Colorectal Cancer Screening Decision-Making Among Older Adults At The Comprehensive Geriatric Clinic, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Chalisa Thanapura, Nawasiri Siriprasert, Thacha Pithayapibulpong, Bhorn-Ake Manasvanich, Vichai Viriyautsahakul

Chulalongkorn Medical Journal

Abstract

Background: The incidence of colorectal cancer (CRC) in Thailand is constantly increasing, and is highest in individuals aged 60-75 years. However, the number of older individuals undergoing CRC screening remains suboptimal.

Objective: This study aimed to identify factors associated with CRC screening decision-making among Thai older adults attending the Comprehensive Geriatric Clinic at King Chulalongkorn Memorial Hospital. The secondary objective was to identify factors associated with the choice of screening method—colonoscopy versus fecal occult blood testing (FOBT)

Methods: A cross-sectional study was conducted using a data record form at the Comprehensive Geriatrics Clinic, King Chulalongkorn Memorial Hospital in Bangkok, …

Integrative Analysis Of Bioinformatics Databases To Identify Thyroid Cancer Drug Target Candidates, Desti Rahmawati, Putri Permata Suka Admanegara, Rista Yulianti, Siska Widiastuti, Wirawan Adikusuma, Brilliant Citra Wirashada, Rahmat Dani Satria, Darmawi Darmawi, Baik Heni Rispawati, Rockie Chong, Ilker Ates, Lalu Muhammad Irham, Petrina Theda Philothra

Chulalongkorn Medical Journal

Background: Thyroid cancer is an endocrine malignancy whose incidence continues to rise globally. Although thyroid cancer generally has a favourable prognosis, aggressive subtypes such as anaplastic thyroid cancer remain a therapeutic challenge. Drug repurposing strategies offer the opportunity to accelerate the development of therapies by utilising drugs already available and with an established safety profile.

Objective: This study aims to identify candidate thyroid cancer risk genes by analyzing data extracted from GWAS and PheWAS databases, and to evaluate their potential therapeutic relevance through drug repositioning

Methods: Significant gene variants were obtained from GWAS and PheWAS databases and functionally annotated …

The Mathematical Model Predicts Peripheral Blood Cd34+ Cell Yield And Blood Volume Processing For Peripheral Blood Stem Cell Apheresis., Rattaporn Vichitratchaneekorn, Kanokpol Siriphanthong, Kanokwan Chinbordee, Phandee Watanaboonyongcharoen, Ponlapat Ronjnuckarin

Chulalongkorn Medical Journal

Introduction: The accurate prediction of stem cell yields is important for planning peripheral blood stem cell (PBSC) collection. This study aimed to develop a formula forecasting required blood volume processing to ensure adequate CD34+ cell products.

Methods: Data from donors and patients who underwent PBSC apheresis conducted at a tertiary care hospital were reviewed. BD FACSCanto™ II and Navios EX flow cytometry machines were used to determine the pre-collection CD34+ cell counts (preCD34).

Results: Of 50 donors and 85 patients, 145 leukapheresis procedures were performed. Linear regression models accurately predicted absolute CD34+ cell yields from pre-apheresis values, supporting optimal procedural …

Ameliorative Effect Of Ethanolic Extract Of Nardostachys Jatamansi Against High Fat Diet Induced Dyslipidemia In Rats, Umanath Preethi, Govindaraj Sumathy, Nathiya Shanmugam

Chulalongkorn Medical Journal

ABSTRACT:

Background and objective: The present study aimed to evaluate the antioxidant and hypolipidemic effects of ethanol extract of Nardostachys Jatamansi (N.J) in a high-fat diet-induced obesity model in male Wistar albino rats.Materials and methods:36 male Wistar albino rats were randomly divided into six groups, each comprising six animals: Group I received a normal diet for 9 weeks, while Group II was fed a high-fat diet (HFD) for the same period. Groups III–VI were also given HFD throughout. From week 5, Group III received rosuvastatin (10 mg/kg), and Groups IV–VI were treated with Nardostachys Jatamansi. extract at 100, 200, and …

Machine Learning-Based Gene Signature Detection Highlights Cxcl12 As A Key Marker For Aml Prediction, Selahattin Alperen Uysal, Burçin Kaymaz

Chulalongkorn Medical Journal

Background: Acute myeloid leukemia (AML) is a severe hematologic malignancy marked by uncontrolled proliferation and impaired differentiation of myeloid cells, disrupting normal hematopoiesis and resulting in poor clinical outcomes. Conventional diagnostic approaches often lack the precision to accurately classify AML subtypes, necessitating the integration of advanced computational methods to improve diagnostic and therapeutic strategies.

Objectives: This study aimed to apply machine learning (ML) techniques to transcriptomic data in order to identify a concise and informative gene signature capable of distinguishing AML cases from normal samples. Additionally, the study sought to evaluate the performance of predictive models in supporting AML prediction …

Assessing The Reliability Of Machine Learning Models In Classifying Depression Severity Using Facebook Text, Keito Yoneyama

Chulalongkorn Medical Journal

Depression is a growing global issue that requires urgent attention, particularly in Thailand. Without timely intervention, it can lead to serious consequences such as health complications, reduced social participation, and even suicide. Consequently, there has been increased research focused on developing algorithms to identify and classify social media data according to depression severity. This study aimed to evaluate the extent to which such algorithms are a suitable tool for the preliminary classification of Thai Facebook text into different levels of depression severity. The methodology involved data collection through surveys and Facebook scraping, followed by data preprocessing, feature engineering, and model …

Distribution Of Urinary Calculi And Its Association With Clinical And Laboratory Findings In Dogs And Cats With Stone Analysis At Chulalongkorn Animal Teaching Hospital, Thailand (2020-2024), Tanattha Ladabornvidhaya, Natkrita Baikloy, Theaparak Thipjaroen, Parapond Kongrakchang, Warisara Kaechaiya, Sumonwan Chamsuwan, Monkon Trisiriroj, Chollada Buranakarl

The Thai Journal of Veterinary Medicine

Urinary calculi are commonly encountered in veterinary practice; however, information regarding their distribution of stone that underwent analysis and associated clinical findings remains limited. This study investigated the distribution of urolithiasis and the associations between stone types and clinical and laboratory findings in dogs and cats presented to the Chulalongkorn Small Animal Teaching Hospital between 2020 and 2024. The three most common stone types in both species were calcium oxalate (CaOx), struvite, and urate, with relatively stable trends over the 5-year period. Small-breed dogs had a higher risk of developing CaOx urolithiasis than medium-breed dogs (OR = 10.4, 95% CI …

Minimally Invasive Percutaneous Endoscopic Foraminotomy And Discectomy In A French Bulldog With Intervertebral Disc Extrusion, Tanhatai Krajarngjang, Luksamee Limpongsai, Panutda Darapong, Woraphanit Sonbanpai, Mataya Taweechart

The Thai Journal of Veterinary Medicine

A six-year-old female French Bulldog was referred for neurological diagnostic tests and treatment for progressive paraparesis over an 8-day period. The dog had a history of intervertebral disc extrusion (IVDE) surgical correction two years prior. Neurological examination revealed T3–L3 myelopathy. Magnetic resonance imaging of the thoracolumbar spine confirmed IVDE with spinal cord compression at T13–L1. A minimally invasive percutaneous endoscopic foraminotomy and discectomy (PEFD) was performed to remove the extruded disc material. The patient regained the ability to stand and showed voluntary limb movement 48 hours post-surgery. At the 4-week follow-up, the patient showed a complete recovery to her baseline …

Acemannan/Alginate Composite Hydrogels Promote Sto Cell Spreading And Metabolic Activity, Hong Yongxing, Tharasanit Theerawat

The Thai Journal of Veterinary Medicine

Alginate-based hydrogels are widely used as biocompatible scaffolds. However, their limited cell-adhesive properties restrict their application in tissue engineering. This study aimed to fabricate acemannan/alginate (ACE/ALG) composite hydrogels and evaluate their cytocompatibility and ability to support STO cell spreading and metabolic activity. Composite hydrogels were prepared by blending different concentrations of ACE with alginate, followed by Ca²⁺-mediated ionic crosslinking. Rheological analysis showed that ACE incorporation increased both the storage modulus (G′) and loss modulus (G″) of the hydrogels. Cell viability and morphology were evaluated using Live/Dead staining on day 7, and cellular growth was assessed using an MTT assay on …

Multidrug Resistance, Extended-Spectrum Β-Lactamase (Esbl) Production, And Colistin Resistance In Escherichia Coli From Retail Chicken Meat In Fresh Markets In Bangkok, Thailand, Htet Lin Oo, Nawaphorn Roongrojmongkhon, Suwanee Chalermchainukul, Sirawit Pagdepanichkit

The Thai Journal of Veterinary Medicine

Contamination of chicken meat with antimicrobial-resistant bacteria, particularly multidrug-resistant (MDR), colistin-resistant, and extended-spectrum β-lactamase (ESBL)-producing Escherichia coli (E. coli), threatens its safety for human consumption. This study was conducted to determine the prevalence and antimicrobial resistance (AMR) profiles, particularly ESBL production and colistin resistance in E. coli isolated from retail chicken meat in fresh markets in Bangkok, Thailand. A total of 200 (81.6%) E. coli isolates were recovered from 245 chicken meat samples collected from fresh markets across six regions of Bangkok. Among the isolates, 189 (94.5%) exhibited resistance to at least one antimicrobial agent tested, with the …

Investigation Of The Functional Dimensions Of Teats Up To Mid-Lactation In Bulgarian Murrah Buffaloes Established By Ultrasonography, Ivan Fasulkov, Pencho Penchev, Yordanka Ilieva, Manol Karadaev

The Thai Journal of Veterinary Medicine

The aim of this study was to monitor the changes in teat measurements from early to mid-lactation in the Bulgarian Murrah buffaloes. The experiment was carried out with twenty (10 primiparous and 10 pluriparous) lactating buffaloes. Five series of ultrasound measurements were performed, each consisting of two sessions for each animal corresponding to the phases of lactation: first lactation month (day 1 to day 30 postpartum) and mid- lactation (day 122 to day 152). The studied parameters were teat canal length (TCL), teat diameter (TD), teat wall thickness (TWT), and teat cistern diameter (TCD). The data were processed using the …

Radiographic Evaluation Of Kidney Size In Cats: Effects Of Sex And Gonadal Status, Somchin Sutthigran, Auraiwan Klaengkaew, Chutimon Thanaboonnipat, Suppawiwat Ponglowhapan, Nan Choisunirachon

The Thai Journal of Veterinary Medicine

Radiographic evaluation of kidney size using the kidney-to-second lumbar vertebral body length (K/L2) ratio is a standard method for assessing kidney size in cats. However, current reference values underdetermine biological factors such as sex and gonadal status, which may influence kidney and lumbar length. Reproductive hormones are known to influence kidney and vertebral development, but their specific effects on radiographic kidney and vertebral measurements in cats are unclear. This retrospective study aimed to assess the effects of gonadal status on kidney length, L2 vertebral length, and the K/L2 ratio in clinically healthy cats. A total of 285 cats were included …

Transfemoral Approach To Patent Ductus Arteriosus Occlusion Using Acdo In A Dog With Complex Surgical History, Nawat Sannamwong, Hataichon Owatdhumma, Kornrawee Tharavanij, Thitinan Tangarsasilp, Nardtiwa Chaivoravitsakul, Kongthit Horoongruang, Patmanachatr Bunnag, Nakkawee Saengklub, Krishaporn Kradangnga, Sirilak Disatian Surachetpong, Anusak Kijtawornrat

The Thai Journal of Veterinary Medicine

A five-year-old spayed female Welsh Corgi weighing 12.4 kg presented with exercise intolerance and was diagnosed with a patent ductus arteriosus (PDA). Due to signs of left-sided volume overload, the dog was initially managed with oral pimobendan and was subsequently referred to the Small Animal Teaching Hospital at Chulalongkorn University for further evaluation and intervention. Upon presentation, the patient was bright, alert, and responsive, with a body condition score of 6 out of 9 and normal muscle condition. The mucous membranes were pink and moist, with a capillary refill time of 1 to 2 seconds. A continuous heart murmur was …