Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

2023

Discipline
Institution
Keyword
Publication
Publication Type
File Type

Articles 1 - 30 of 27418

Full-Text Articles in Medicine and Health Sciences

Influence Of Beta And Theta Waves As Predictors Of Simple And Complex Reaction Times In Examined Groups Of Judo Athletes During The Vienna Test, Magdalena Pronczuk, Tomasz Chamera, Alicja Markiel, Jerzy Markowski, Jan Pilch, Piotr Żmijewski, Adam Maszczyk Dec 2023

Influence Of Beta And Theta Waves As Predictors Of Simple And Complex Reaction Times In Examined Groups Of Judo Athletes During The Vienna Test, Magdalena Pronczuk, Tomasz Chamera, Alicja Markiel, Jerzy Markowski, Jan Pilch, Piotr Żmijewski, Adam Maszczyk

Baltic Journal of Health and Physical Activity

Introduction: This research aimed to investigate which waves, Theta or Beta, are significant predictors of visual simple and complex reaction times during the Vienna test, using regression modeling. The research material comprised the test results of male judo athletes (n = 24), selected through mixed sampling (purposive and random). The study was conducted in two cycles, differentiated by frequency but with the same duration of EEG biofeedback sessions, in both the control and experimental groups. The first cycle of the study consisted of 15 sessions held every other day. Each training session lasted for 4 minutes. The second series …


The Effectiveness Of Resistance Exercises Performed On Stable And Unstable Surfaces In Relation To Torso Activation, Radim Jebavy, Dusan Blazek, Helena Vomackova, Jan Vavra, Jan Busta, Anna Pisz, Petr Stastny Dec 2023

The Effectiveness Of Resistance Exercises Performed On Stable And Unstable Surfaces In Relation To Torso Activation, Radim Jebavy, Dusan Blazek, Helena Vomackova, Jan Vavra, Jan Busta, Anna Pisz, Petr Stastny

Baltic Journal of Health and Physical Activity

Introduction: Deep stabilization system (DSS) strength and endurance are crucial for injury prevention and athletic performance. Training surfaces can influence training outcomes; therefore, this study aimed to compare the impact of performing strength trunk exercises on unstable and stable surfaces with conventional trunk exercises. Materials and Methods: DSS and trunk stability were assessed before and after 10 weeks of three different training interventions among twenty elite futsal players. Each intervention included 25 strength training sessions. Pre- and post-tests encompassed various measurements, including diaphragm, trunk flexion, trunk back extension, hip flexion, intraabdominal pressure, side plank, pronation, and supination tests. Results: Conventional …


Literature Review: Nutrition Supplementation For Muscle Fatigue In Athletes, Mardiana Mardiana, Apoina Kartini, Dwi Sutiningsih, Suroto Suroto, Muhammad Solihuddin Muhtar Dec 2023

Literature Review: Nutrition Supplementation For Muscle Fatigue In Athletes, Mardiana Mardiana, Apoina Kartini, Dwi Sutiningsih, Suroto Suroto, Muhammad Solihuddin Muhtar

Jurnal Keolahragaan

The use of natural or conventional-based supplementation has become a popular strategy among athletes seeking to reduce oxidative stress, improve recovery, and enhance athletic performance. This literature review searched four reputable international electronic databases, including PubMed, MedRxiv, Cochrane, and Clinical Trial.gov until December 2021, using Boolean operators with keywords and Mesh methods. The keywords used were "Supplementation", AND "Muscle Fatigue Recovery", AND "Athletes", which yielded 24 articles as study findings. The literature review found that exhaustive exercise can induce a neutrophil antioxidant response by increasing antioxidant enzymes. Nutritional supplements, specifically antioxidant supplements, Branched Chain Amino Acid (BCAA), citrulline, omega-3, and …


Novel Anti-Influenza Monoclonal Antibodies, Ozlem Gurses Dec 2023

Novel Anti-Influenza Monoclonal Antibodies, Ozlem Gurses

NYMC Student Theses and Dissertations

There is a continual public threat of influenza virus infections. This is related to viruses evolving in multiple animal reservoirs, making infection prevention in humans difficult to achieve and leading to seasonal epidemics and the semi-regular emergence of pandemics. Novel antibody-based therapies are of great interest to researchers because of a dramatic increase in drug resistant strains of influenza viruses. The identification of cross-reactive and broadly protective monoclonal antibodies targeting the influenza proteins presents a promising prospect for the development of a universal therapy. Although the research related to the monoclonal antibodies targeting the viral internal proteins is limited, multiple …


Uji Coba Pemberian Snack Bars Berbahan Dasar Tape Ketan Hitam Sebagai Sumber Serat Terhadap Penurunan Kadar Glukosa Darah Puasa Pasien Diabetes Melitus Tipe 2, Muhammad Muayyad Billah, Budiyanti Wiboworini, Adi Prayitno Dec 2023

Uji Coba Pemberian Snack Bars Berbahan Dasar Tape Ketan Hitam Sebagai Sumber Serat Terhadap Penurunan Kadar Glukosa Darah Puasa Pasien Diabetes Melitus Tipe 2, Muhammad Muayyad Billah, Budiyanti Wiboworini, Adi Prayitno

Jurnal Penyakit Dalam Indonesia

Introduction. Managing dietary pattern, including snack schedule, is one of the most important factors in maintaining blood glucose levels in patients with type 2 diabetes mellitus (T2DM). Black glutinous rice tape is one of the foods that contains bioactive nutrient and fiber beneficial to health. This study aimed to determine the effect of snack bars made from black glutinous rice tape on fasting blood glucose levels in T2DM patients.

Methods. The study employed a quasi-experimental pre and post-test design with a control group which was conducted among T2DM patients undergoing treatment at Bhayangkara Tk. II Sartika Asih Hospital, …


Survei Kebutuhan Edukasi Pasien Lupus Eritematosus Sistemik, Jennifer Josephine, Alvina Widhani, Rahmat Cahyanur, Teguh Harjono Karjadi Dec 2023

Survei Kebutuhan Edukasi Pasien Lupus Eritematosus Sistemik, Jennifer Josephine, Alvina Widhani, Rahmat Cahyanur, Teguh Harjono Karjadi

Jurnal Penyakit Dalam Indonesia

Introduction. Patients with systemic lupus erythematosus (SLE) who suffer from chronic illness, need tailored education to better manage their condition. As nowadays education through internet and social media contributes significantly. This study aimed to assess internet usage related to lupus, educational needs, and education sources preferences among patients.

Methods. This study was a cross-sectional study conducted on adult SLE patients at Allergy and Clinical Immunology Clinic, Internal Medicine Department, Cipto Mangunkusumo Hospital, Jakarta, between July-August 2023. Respondents completed a set of questionnaires regarding their internet usage related to lupus, education platform preferences, and educational needs assessment tool (ENAT). …


Modifikasi Skor Timi Sebagai Model Prediksi Mortalitas 30 Hari Pasien Stemi Muda, M. Tasrif Mansur, Muhammad Yamin, Lusiani Rusdi, Murdani Abdullah, Birry Karim, Cleopas Martin Rumende, Maruhum Bonar H. Marbun, Hamzah Shatri Dec 2023

Modifikasi Skor Timi Sebagai Model Prediksi Mortalitas 30 Hari Pasien Stemi Muda, M. Tasrif Mansur, Muhammad Yamin, Lusiani Rusdi, Murdani Abdullah, Birry Karim, Cleopas Martin Rumende, Maruhum Bonar H. Marbun, Hamzah Shatri

Jurnal Penyakit Dalam Indonesia

Introduction. Cardiovascular disease is a leading cause of death worldwide. Three-quarters of these deaths occur in lowand middle-income countries among individuals in their productive years. ST-segment elevation myocardial infarction (STEMI) is a dangerous manifestation of coronary artery disease (CAD) and can lead to sudden death. Smoking and a family history of early CAD are major risk factors for STEMI cases. However, their role in any risk stratification system for patients has not been clearly established. The most widely used score in assessing the prognosis of STEMI patients is the TIMI score, but its accuracy in the young patient population …


Efektivitas Sacubitril/Valsartan Dalam Mencegah Gagal Jantung Pada Stemi Pasca Percutaneous Coronary Intervention, Nobian Andre, Lana Adila, Aulia Rizka, Lusiani Rusdi Dec 2023

Efektivitas Sacubitril/Valsartan Dalam Mencegah Gagal Jantung Pada Stemi Pasca Percutaneous Coronary Intervention, Nobian Andre, Lana Adila, Aulia Rizka, Lusiani Rusdi

Jurnal Penyakit Dalam Indonesia

Heart failure is a possible complication following ST-elevation myocardial infarction (STEMI) even after revascularization. Neuroendocrine activation in the process of ventricular remodeling can be regulated by angiotensin receptor-neprilysin inhibitor (ARNI) as well as angiotensin-converting enzyme (ACE) inhibitor. The use of ARNI in heart failure with reduced ejection fraction has been found to be superior to ACE inhibitor. The role of ARNI on cardiac function in STEMI has not been established. A clinician treating a patient with STEMI considered giving sacubitril/valsartan to reduce the risk of developing heart failure. Literature search was performed in three electronic databases: PubMed, Embase, and Cochrane. …


Pentingnya Edukasi Pasien Lupus Eritematosus Sistemik, Evy Yunihastuti, Fadlika Harinda Dec 2023

Pentingnya Edukasi Pasien Lupus Eritematosus Sistemik, Evy Yunihastuti, Fadlika Harinda

Jurnal Penyakit Dalam Indonesia

Lupus eritematosus sistemik (LES) merupakan penyakit kronik yang dapat mengenai berbagai macam organ dengan manifestasi ringan hingga serius. Karakteristik LES adalah sangat dinamis, bervariasi, dengan perjalanan penyakit yang kadang tidak dapat diprediksi. Walau saat ini semakin tinggi pengetahuan tentang patofisiologi, optimalisasi penanganan, dan banyak ditemukan obat yang lebih baik untuk terapi LES, masih banyak ODAPUS (orang dengan lupus) mengalami morbiditas, mortalitas, dan kualitas hidup yang kurang baik. Tanpa penanganan yang baik, pemantauan dan pengobatan yang teratur, tentu luaran yang baik akan lebih sulit didapatkan.


Kombinasi Sofosbuvir-Ledipasvir Dan Sofosbuvir- Daclatasvir Pada Pengobatan Pasien Hepatitis C Di Indonesia, Andri Sanityoso Sulaiman Dr, Irsan Hasan Dr, Cosmas Rinaldi Adithya Lesmana Dr, Juferdy Kurniawan Dr, Gita Aprilicia, Yayah Nugroho Dr, Nunuk Tri Wahyuni Dr, Budiman Sujatmika Sulaiman Dec 2023

Kombinasi Sofosbuvir-Ledipasvir Dan Sofosbuvir- Daclatasvir Pada Pengobatan Pasien Hepatitis C Di Indonesia, Andri Sanityoso Sulaiman Dr, Irsan Hasan Dr, Cosmas Rinaldi Adithya Lesmana Dr, Juferdy Kurniawan Dr, Gita Aprilicia, Yayah Nugroho Dr, Nunuk Tri Wahyuni Dr, Budiman Sujatmika Sulaiman

Jurnal Penyakit Dalam Indonesia

Introduction. Direct-acting antivirals (DAAs) has been developed for treatment hepatitis C virus (HCV). Therapy of HCV using DAA has shown high sustained virologic response (SVR) and shortening duration of therapy. Sofosbuvir-ledipasvir (SOF/LDV) is fixed dose combination tablet of DAAs which recommended for genotype 1, 4, 5, and 6 infected patients. In developing countries, SOF/LDV still can be used as cost-effective regimen in all genotype compared with sofosbuvir-daclatasvir (SOF/ DCV). This study aimed to evaluate the efficacy of combination sofosbuvir-ledipasvir in all genotypes of HCV patients compared with available DAA in Indonesia (sofosbuvir- daclatasvir).

Methods. A retrospective study was …


Angka Kejadian Dan Karakteristik Klinis Pasien Infeksi Jamur Invasif Di Rsup Dr. Hasan Sadikin Tahun 2020 – 2022, Ariella Alessandro, Nisa Fauziah, Imam Megantara, Rudi Wisaksana, Intan Mauli Warma Dewi Dec 2023

Angka Kejadian Dan Karakteristik Klinis Pasien Infeksi Jamur Invasif Di Rsup Dr. Hasan Sadikin Tahun 2020 – 2022, Ariella Alessandro, Nisa Fauziah, Imam Megantara, Rudi Wisaksana, Intan Mauli Warma Dewi

Jurnal Penyakit Dalam Indonesia

Introduction. Invasive fungal infection (IFI) is increasingly common in patients at risk, especially those with impaired immune response. In Indonesia, there is currently a low prevalence of IFI which may be influenced by challenges in diagnosis. This study aimed to determine the prevalence and clinical characteristics of IFI patients in Dr. Hasan Sadikin Hospital in Bandung, Indonesia.

Methods. This cross-sectional study was conducted at Dr. Hasan Sadikin Hospital. Data were collected using medical records of IFI patients diagnosed between 2020 and 2022 which were selected using total sampling method. Demographic data, clinical symptoms, radiological appearance, and laboratory results …


Penyakit Sel Sabit Pada Pasien Laki-Laki Berusia 27 Tahun Yang Sebelumnya Didiagnosis Sebagai Talasemia: Sebuah Laporan Kasus, Rahmat Cahyanur, Andree Kurniawan, Ratuafni Sharfina, Nadia Ayu Mulansari Dec 2023

Penyakit Sel Sabit Pada Pasien Laki-Laki Berusia 27 Tahun Yang Sebelumnya Didiagnosis Sebagai Talasemia: Sebuah Laporan Kasus, Rahmat Cahyanur, Andree Kurniawan, Ratuafni Sharfina, Nadia Ayu Mulansari

Jurnal Penyakit Dalam Indonesia

Sickle cell disease (SCD) is a hemoglobinopathy inherited in an autosomal recessive pattern arising from a mutation causing substitution of valine for glutamic acid in the sixth amino acid of the β-globin chain. The clinical manifestation of SCD varies from acute pain, chronic anemia, to multi-organ infarct and failure. SCD is known to be rare in Indonesia. However, we recently encountered a SCD patient presenting with recurrent pain and hypesthesia since a year ago. The diagnosis of SCD in this patient was established based on the results of peripheral blood smear and hemoglobin electrophoresis. The patient had previously been diagnosed …


Konsep Diagnosis Dan Penatalaksanaan Fraktur Osteoporosis Terkini, I Gusti Ngurah Wien Aryana, Febyan Febyan Dec 2023

Konsep Diagnosis Dan Penatalaksanaan Fraktur Osteoporosis Terkini, I Gusti Ngurah Wien Aryana, Febyan Febyan

Jurnal Penyakit Dalam Indonesia

Osteoporosis is a metabolic bone disease that is caused by a decreased amount of bone mass, and microarchitectural damage to bone tissue that affects the bone to break easily. Osteoporosis can be divided into primary and secondary etiologies. Vertebral, hip, distal radius, and proximal humerus are the most common predilection of fracture complication due to osteoporosis. The diagnosis of osteoporotic fractures is established based on the identification of risk factors, general clinical manifestations, specific manifestation from each fracture predilection, and advanced examinations, including radiology imaging and dual-energy x-ray absorptiometry. The purpose of osteoporotic fractures management in elderly is a stable …


Tandem Walking Exercise To Improve Cognitive Function In The Elderly, I Made Dhita Prianthara, Iga Sri Wahyuni Novianti, I Putu Prisa Jaya, Ni Putu Diah Anantari, Ni Kadek Yuni Fridayani Dec 2023

Tandem Walking Exercise To Improve Cognitive Function In The Elderly, I Made Dhita Prianthara, Iga Sri Wahyuni Novianti, I Putu Prisa Jaya, Ni Putu Diah Anantari, Ni Kadek Yuni Fridayani

Jurnal Keolahragaan

Decreased cognitive function in the elderly is the leading cause of inability to carry out normal daily activities, as well as a high level of reliance on others in caring for themselves. The many problems that arise due to decreased cognitive function require a healthy aging process so that decreased cognitive function does not cause health problems in the lives of the elderly. Decreased cognitive function in the elderly is the biggest cause of inability to carry out normal daily activities and is also the cause of the elderly experiencing a high level of dependence on others in caring for …


A Perspective On The Strategy For Advancing Etvax, An Anti-Etec Diarrheal Disease Vaccine, Into A Field Efficacy Trial In Gambian Children: Rationale, Challenges, Lessons Learned, And Future Directions, M Jahangir Hossain, Ann-Mari Svennerholm, Nils Carlin, Umberto D'Alessandro, Thomas F Wierzba Dec 2023

A Perspective On The Strategy For Advancing Etvax, An Anti-Etec Diarrheal Disease Vaccine, Into A Field Efficacy Trial In Gambian Children: Rationale, Challenges, Lessons Learned, And Future Directions, M Jahangir Hossain, Ann-Mari Svennerholm, Nils Carlin, Umberto D'Alessandro, Thomas F Wierzba

Faculty and Staff Publications

For the first time in over 20 years, an Enterotoxigenic Escherichia coli (ETEC) vaccine candidate, ETVAX®, has advanced into a phase 2b field efficacy trial for children 6-18 months of age in a low-income country. ETVAX® is an inactivated whole cell vaccine that has gone through a series of clinical trials to provide a rationale for the design elements of the Phase 2b trial. This trial is now underway in The Gambia and will be a precursor to an upcoming pivotal phase 3 trial. To reach this point, numerous findings were brought together to define factors such as safe and …


Ameliorative Effects Of Fmrfamide On 3,4-Methylenedioxyl-Methamphetamine/Tramadol-Induced Neurodegeneration In The Hippocampus, O. E. Ogunbiyi, K. O. Adeniji, L. Arietarhire, P. Okwute, D. Abaneme, J. I. Enya, O. Soremekun, M. Adekunle, O. Soyinka, S. T. Adelodun, S. Y. Olatunji, T. Afolabi, T. P. Ajibade, A. G. Obaoye, M. Dada, Joshua Owolabi, John A. Olanrewaju Dec 2023

Ameliorative Effects Of Fmrfamide On 3,4-Methylenedioxyl-Methamphetamine/Tramadol-Induced Neurodegeneration In The Hippocampus, O. E. Ogunbiyi, K. O. Adeniji, L. Arietarhire, P. Okwute, D. Abaneme, J. I. Enya, O. Soremekun, M. Adekunle, O. Soyinka, S. T. Adelodun, S. Y. Olatunji, T. Afolabi, T. P. Ajibade, A. G. Obaoye, M. Dada, Joshua Owolabi, John A. Olanrewaju

PCOM Scholarly Works

Objective: Tramadol and 3,4-methylenedioxy-methamphetamine (MDMA) use over an extended period is linked to deficits in memory encoding and retrieval. We aimed to determine the neurotoxic effects of co-administration of MDMA and tramadol (TRAM) on hippocampal function and investigate the potential of FMRFamide in attenuating resulting alterations in the Wistar rat model. Methods: Thirty adult male Wistar rats were grouped into six (n=5): Control, FMRFamide, TRAM, MDMA, TRAM+MDMA, and TRAM + MDMA + FMRFamide groups. The opiates were administered orally at 20mg/kg each, while 2mg/kg of FMRFamide was administered intraperitoneally for 12 days using normal saline as a vehicle. The Barnes …


A Rare Occurrence Of Ectopic Parathyroid Carcinoma Presenting As A Case Of Recurrent Fractures, Saad Bin Zafar Mahmood, Aisha Jamal, Zain Mushtaq, Qamar Masood Dec 2023

A Rare Occurrence Of Ectopic Parathyroid Carcinoma Presenting As A Case Of Recurrent Fractures, Saad Bin Zafar Mahmood, Aisha Jamal, Zain Mushtaq, Qamar Masood

Section of Internal Medicine

Ectopic parathyroid tumors are uncommon, accounting for only 6% of parathyroid adenomas, and even fewer cases are attributed to parathyroid carcinomas. While ectopic parathyroid carcinoma in the anterior mediastinum is a rare condition, the occurrence of recurrent skeletal fractures in the presence of mild hypercalcemia is even rarer. In this report, we present the case of a 52-year-old man with a medical history of hypertension, chronic kidney disease, and a previous right-sided intertrochanteric fracture of the femur one year earlier. He presented to the emergency room with left-sided hip pain and shortness of breath due to volume overload. Laboratory tests …


Workplace Stress Of Special School Teachers At Three Schools In Bali Province, Made Adhyatma Prawira Natha Kusuma, Agnes Ayu Biomi, Luh Putu Wulandari Artha Dec 2023

Workplace Stress Of Special School Teachers At Three Schools In Bali Province, Made Adhyatma Prawira Natha Kusuma, Agnes Ayu Biomi, Luh Putu Wulandari Artha

Preventia: The Indonesian Journal of Public Health

Workplace stress is often seen as a threat or a problem that comes from the work environment. Stress is a feeling resulting from the interaction between the individual and the work environment. Work stress can happen to anyone at any time, including special school teachers. This research aims to describe the workplace stress of special school teachers at three schools in the Bali Province. This research was conducted in October-December 2022. Researcher used quantitative research method with cross-sectional design and descriptive approach. Data collection is carried out using the Copenhagen Psychosocial Questionnaire-III and the Occupational Diagnosis Survey from the Ministry …


Factors Associated With Reproductive Health Knowledge Among Vocational School Students In Padang, Wilda Tri Yuliza, Meti Yanti, Alkafi Alkafi, Gusni Rahma Dec 2023

Factors Associated With Reproductive Health Knowledge Among Vocational School Students In Padang, Wilda Tri Yuliza, Meti Yanti, Alkafi Alkafi, Gusni Rahma

Preventia: The Indonesian Journal of Public Health

The Ministry of Health of the Republic of Indonesia in 2022 reported that 35.3 persen of women and 31.2 persen of men aged 15-19 have limited or no awareness of reproductive health. The rise of vocational students who are often caught in raids with several cases including sexual deviations is a fatal impact of the lack of reproductive health knowledge on adolescence. The purpose of this study is to find out the factors associated with reproductive health knowledge among vocational students in Padang City. A cross-sectional quantitative research was conducted in July-September 2023 among 538 students at SMK in Padang, …


A Position Analysis Of Bpjs Claims Administration Officers And Verifiers (Case Study: Jambi Province Regional Mental Hospital), Hanisah Hanisah, Asmaripa Ainy, Iwan Stia Budi Dec 2023

A Position Analysis Of Bpjs Claims Administration Officers And Verifiers (Case Study: Jambi Province Regional Mental Hospital), Hanisah Hanisah, Asmaripa Ainy, Iwan Stia Budi

Preventia: The Indonesian Journal of Public Health

The high coverage rate of handling partially rejected claim financing reaching 7.34% of the total 19,476 cases in the Outpatient Unit of the Jambi Provincial Mental Hospital (RSJD) in 2022, is closely related to the quality of human resources (HR) in this case, the claims officer and the suitability of what is done with the job description, job specifications and standard operating procedures (SOP) that have been made. This study aimed to analyze the position of administrative officers and claim verifiers in the outpatient unit of the Jambi Provincial Mental Hospital. This research used a qualitative method. Information was collected …


High-Risk Individuals And Naloxone Use: Implications For Thn Programs In Rural Appalachian Communities, Victor Garcia, Lisa Mccann, Erick Lauber, Christian Vaccaro, Melissa Swauger, Alex Daniel Heckert Dec 2023

High-Risk Individuals And Naloxone Use: Implications For Thn Programs In Rural Appalachian Communities, Victor Garcia, Lisa Mccann, Erick Lauber, Christian Vaccaro, Melissa Swauger, Alex Daniel Heckert

Journal of Appalachian Health

Introduction: Take-home naloxone (THN) is being made available across rural Appalachia to curb opioid overdose fatalities. Despite this initiative, some opioid users do not possess naloxone, and if they do, do not administer it to others.

Purpose: Research findings on risk factors that contribute to opioid overdose are presented. These factors, identified in a sample of 16 overdose cases, are (1) early onset age of opioid use; (2) progressive opioid use; (3) a transition from pain medication to heroin and fentanyl; (4) fears of being arrested at a naloxone intervention if first responders are contacted, and (5) limited knowledge of …


Changes In Perceptions Of First Responders After Witnessing A Drug Overdose: Individual And Contextual Variations Among People Who Use Opioids In West Virginia, Kathleen L. Egan, Kelly Gurka, Alexandria Macmadu, Herb Linn Dec 2023

Changes In Perceptions Of First Responders After Witnessing A Drug Overdose: Individual And Contextual Variations Among People Who Use Opioids In West Virginia, Kathleen L. Egan, Kelly Gurka, Alexandria Macmadu, Herb Linn

Journal of Appalachian Health

Introduction: Success of opioid overdose interventions involving first responders is dependent on the comfort level that bystanders have with first responders and their willingness to call for assistance. Positive or negative experiences with first responders following witnessing an overdose may influence a person’s willingness to call a first responder for assistance in the future.

Purpose: The objective of this study was to examine changes in bystanders’ perceptions of first responders following witnessing an overdose attended by emergency medical services or a law enforcement official. It specifically explored perception changes among a sample of individuals residing in Appalachia who use prescription …


Disparities In Mortality Between Appalachian And Non-Appalachian Regions Of Kentucky, Sonali S. Salunkhe, Sahal Alzahrani, Beatrice Ugiliweneza Dec 2023

Disparities In Mortality Between Appalachian And Non-Appalachian Regions Of Kentucky, Sonali S. Salunkhe, Sahal Alzahrani, Beatrice Ugiliweneza

Journal of Appalachian Health

Introduction: In the opioid epidemic, the U.S. faces a significant public health crisis, with some areas of the country, such as rural and Appalachian regions, suffering more than others. The differential regional impact of the crisis in Kentucky—a state with both non-metropolitan/metropolitan and Appalachian/Non-Appalachian statuses—has not yet been documented despite such knowledge being essential to the success of overdose prevention efforts.

Purpose: This study compares all-cause, drug- and opioid-related mortality between counties in different regions of Kentucky: Appalachian non-metropolitan, Appalachian metropolitan, non-Appalachian non-metropolitan, and non-Appalachian metropolitan.

Methods: Age-adjusted mortality data from the Centers for Disease Control and Prevention’s Wide-ranging Online …


A Suspected Case Of Levetiracetam Induced Rhabdomyolysis, Luke Merrill Ms, Layne Hohn Ms, Marlee Jones Ms, Sydney Gibson Ms, Ty Moody Md, Anthony Breemo Md Dec 2023

A Suspected Case Of Levetiracetam Induced Rhabdomyolysis, Luke Merrill Ms, Layne Hohn Ms, Marlee Jones Ms, Sydney Gibson Ms, Ty Moody Md, Anthony Breemo Md

Aesculapius Journal (Health Sciences & Medicine)

Background: Levetiracetam is a broad-spectrum antiseizure drug which works to terminate convulsions and is used in the treatment of certain types of seizures. It is commonly used to treat epilepsy in adults, and has proven an effective treatment for adults with focal seizures. This drug is normally well tolerated, but commonly reported adverse effects include fatigue, somnolence, and dizziness. A few less common effects have been noted as well, including behavioral disturbances, thrombocytopenia, and—in very few cases—rhabdomyolysis.

Case Report: Our case reports a 55-year-old male who presented to a rural emergency department for active convulsing and unresponsiveness. Initial …


Benzodioxane-Benzamides As Promising Inhibitors Of Escherichia Coli Ftsz, Lorenzo Suigo, Begoña Monterroso, Marta Sobrinos-Sanguino, Carlos Alfonso, Valentina Straniero, Germán Rivas, Silvia Zorrilla, Ermanno Valoti, William Margolin Dec 2023

Benzodioxane-Benzamides As Promising Inhibitors Of Escherichia Coli Ftsz, Lorenzo Suigo, Begoña Monterroso, Marta Sobrinos-Sanguino, Carlos Alfonso, Valentina Straniero, Germán Rivas, Silvia Zorrilla, Ermanno Valoti, William Margolin

Faculty, Staff and Student Publications

The conserved process of cell division in bacteria has been a long-standing target for antimicrobials, although there are few examples of potent broad-spectrum compounds that inhibit this process. Most currently available compounds acting on division are directed towards the FtsZ protein, a self-assembling GTPase that is a central element of the division machinery in most bacteria. Benzodioxane-benzamides are promising candidates, but poorly explored in Gram-negatives. We have tested a number of these compounds on E. coli FtsZ and found that many of them significantly stabilized the polymers against disassembly and reduced the GTPase activity. Reconstitution in crowded cell-like conditions showed …


Spatial Analysis Of The Distribution Of Covid-19 Vulnerable Groups To Covid-19 Cases In Brebes Regency, Fatimatuzzahro Fatimatuzzahro, Rara Warih Gayatri Dec 2023

Spatial Analysis Of The Distribution Of Covid-19 Vulnerable Groups To Covid-19 Cases In Brebes Regency, Fatimatuzzahro Fatimatuzzahro, Rara Warih Gayatri

Preventia: The Indonesian Journal of Public Health

The number of COVID-19 cases in Brebes Regency within a year is still quite high. The elderly, Hypertension and Diabetes Mellitus are the most important COVID-19 vulnerable groups and have the highest risk of death. The purpose of this study is to determine the distribution of COVID-19 vulnerable groups and their spatial relationship to COVID-19 cases in Brebes Regency. This study used a correlation or ecology study design. The data used is secondary data obtained from the Brebes Regency Health Office, namely the number of COVID-19 cases, the number of elderly, people with hypertension and diabetes mellitus in 2021. The …


Bivariate Spatial Pattern Based On The Characteristics Of Women Smokers In Indonesia, Diana Rohmandani Putri, Rudi Safarudin, Ammad Khokar, Konain Tayab, Muhammad Taaha Kashif, Erni Astutik Dec 2023

Bivariate Spatial Pattern Based On The Characteristics Of Women Smokers In Indonesia, Diana Rohmandani Putri, Rudi Safarudin, Ammad Khokar, Konain Tayab, Muhammad Taaha Kashif, Erni Astutik

Preventia: The Indonesian Journal of Public Health

The increasing prevalence of smoking among women globally has become a critical public health issue. World Health Organization (WHO) data shows 20 percent of women use tobacco. Women smokers face an increased risk of various diseases. Spatial studies need to be conducted as a basis for planning and providing targeted interventions to reduce the spread of diseases caused by smoking. The study aimed to determine the spatial description of smoking among women in Indonesia. This study analyzed the 2017 IDHS data and used an ecological study design with a descriptive approach and a spatial analysis model. The results are Papua …


Interest Of Public Health Science Students Of State University Of Malang To Work In Remote Areas, Borders, And Islands, Sapto Adi, Dian Mawarni, Dita Ratna Fauzia Dec 2023

Interest Of Public Health Science Students Of State University Of Malang To Work In Remote Areas, Borders, And Islands, Sapto Adi, Dian Mawarni, Dita Ratna Fauzia

Preventia: The Indonesian Journal of Public Health

The health workforce distribution in Indonesia still needs to be balanced, especially in border areas and islands (DTPK), with no exception for public healthcare workers. This study aimed to determine the interest of public health science students in working in remote areas and the factors associated with the interest of public health science students to work in remote areas. This study design was cross-sectional, and a total sampling method was used. The subjects were final-year students majoring in Public Health Science at the State University of Malang. The dependent variable was the interest of public health science students to work …


Systematic Review Of The Relationship Between Hygiene Practice And The Incidence Of Ascaris Lumbricoides Infection In Southeast Asian Children, Anastasia Rouli Alodia, Ririn Arminsih Wulandari Dec 2023

Systematic Review Of The Relationship Between Hygiene Practice And The Incidence Of Ascaris Lumbricoides Infection In Southeast Asian Children, Anastasia Rouli Alodia, Ririn Arminsih Wulandari

Preventia: The Indonesian Journal of Public Health

Soil-Transmitted Helminth (STH) infection is one of the Neglected Tropical Diseases (NTDs) that affects around 1.5 billion people worldwide, including regions like Southeast Asia. The most common species infecting humans is Ascaris lumbricoides. Preschool-age and school-age children are particularly vulnerable to STH infection due to their living environments in areas where STH is prevalent. Infection of STH, especially Ascaris lumbricoides, can hinder physical and cognitive development and, in severe cases, cause obstruction of the small intestine. Various factors, such as hygiene practices, can influence the transmission of Ascaris lumbricoides infection in children. This study aims to explore the association between …


Tracing Antibacterial Compounds From Kaledang (Artocarpus Lanceifolius Roxb.) Stem Bark, Hamsidar Hasan, Tety Tuloli, Syamsul Bahri, La Ode Aman Dec 2023

Tracing Antibacterial Compounds From Kaledang (Artocarpus Lanceifolius Roxb.) Stem Bark, Hamsidar Hasan, Tety Tuloli, Syamsul Bahri, La Ode Aman

Pharmaceutical Sciences and Research

Artocarpus lanceifolius Roxb. or kaledang is a species of the mulberry family, Moraceae. Several extracts from its family have been reported to have antibacterial activity. Thus, it is necessary to determine compounds that have nature as antibacterial to be raw materials for antibacterial herbal medicines. The purpose of the study was to trace compounds that have antibacterial activity from Artocarpus lanceifolius stem bark. The study method was extraction by graded maceration, fractionation with column vacuum chromatography (CVC), isolation by radial chromatography, determination of antibacterial activity by agar diffusion method using the Gram positive and Gram negative bacteria. The characterization …