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Honors Theses

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Full-Text Articles in Medicine and Health Sciences

Analyzing The Survival Rate Of Clinically Pathogenic Bacteria On Occupational Therapy Devices Used During Full Hip Replacement Rehabilitation, Meredith Rippy May 2022

Analyzing The Survival Rate Of Clinically Pathogenic Bacteria On Occupational Therapy Devices Used During Full Hip Replacement Rehabilitation, Meredith Rippy

Honors Theses

An increasing concern of the healthcare system has been that of Healthcare-Associated Infections (HAIs). HAIs currently account for approximately 1.7 million infections and 99,000 deaths per year in United States hospitals. HAI’s (formerly called nosocomial infections) are defined as infections that develop in patients who have been in residence in a healthcare facility (i.e., in-patient clinics) for 48 hours or longer and who previously had no evidence of infection prior to admission. Consequences of HAIs include increased length of hospital stay, exposure to high frequency antibiotics, sepsis, and in unfortunate cases, death. In out-patient environments where ...


Bacteriophages: Paving The Road For The Future Of Medicine, Luke Brinkerhoff May 2022

Bacteriophages: Paving The Road For The Future Of Medicine, Luke Brinkerhoff

Honors Theses

Bacteriophages are a possible solution to antibiotic resistance, which is predicted to be detrimental world-wide by the year 2050. Personal field research was also conducted for a project studying the characteristics of two bacteriophages on a single bacterial host.


Effects Of Storage Conditions On Bpa Leaching From Infant Oral Hygiene Products Using Fluorescence Spectroscopy, Emma Bynum May 2022

Effects Of Storage Conditions On Bpa Leaching From Infant Oral Hygiene Products Using Fluorescence Spectroscopy, Emma Bynum

Honors Theses

Infants are at the highest risk of BPA exposure compared to any other stage of life. Because an infant’s endocrine system is developing, exposure to an endocrine-disruptor, such as BPA, can be especially harmful. Bisphenol-A (BPA) is a structural component in many plastic products, which acts as an endocrine-disruptor mimicking estrogen. This hormonal disruption has been linked to obesity, reproductive issues, cardiovascular problems, and the neurodevelopment disorders. While the FDA monitors things like baby bottles, canned goods, and plastic containers for BPA, infantile oral hygiene products are not closely monitored. Previous research tested infant toothbrushes on the market using ...


The Various Nervous System Drugs Commonly Used For Treatment And The Disparities In Availability Of These Drugs In Minority Groups, Iman Haurami Apr 2022

The Various Nervous System Drugs Commonly Used For Treatment And The Disparities In Availability Of These Drugs In Minority Groups, Iman Haurami

Honors Theses

The nervous system is a complex network in our body that is responsible for actions, reflexes, and even sensations. With the brain being part of the CNS, many common nervous system disorders are due to a defect in the central nervous system and the functions of this organ. These disorders include mental health problems, degenerative diseases, seizures, infections, and other possible genetic diseases. Many of these diseases are common in society and constantly researched. Even though these diseases are common, treatment accessibility and effects on people of minority groups are overlooked compared to the focus on majority groups. For drug ...


Awareness Of Racial Disparities In Healthcare: An Analysis Of Undergraduate Science Students’ Perceptions, Liz Bleyer Apr 2022

Awareness Of Racial Disparities In Healthcare: An Analysis Of Undergraduate Science Students’ Perceptions, Liz Bleyer

Honors Theses

General and systemic racial inequalities, including slavery, mass incarceration, and health disparities, have existed throughout the history of the United States. Recent public health issues, specifically the COVID-19 pandemic, have shed light on enduring health disparities, including the disproportionate impact on black communities and other racial minorities. A crucial first step towards a more equitable healthcare system is increasing general awareness of the presence and effects of racial disparities. Previous research has quantified and described the awareness of racial disparities in healthcare practitioners, including medical students and practicing physicians, but little research has been dedicated to understanding the perspectives of ...


A Comparison Of Stigma Levels For Individuals With Psychological Disorders And Individuals With Intellectual Disabilities, Isabella E. Wood Apr 2022

A Comparison Of Stigma Levels For Individuals With Psychological Disorders And Individuals With Intellectual Disabilities, Isabella E. Wood

Honors Theses

This study compared nine aspects of stigmatization (blame, anger, pity, help, dangerousness, fear, avoidance, segregation, coercion) amongst schizophrenia, binge eating, and intellectual disabilities. The overall MANOVA was significant, F(18, 183) = 89.95, p < .001, Wilks’ Lambda = .10. When the results for the dependent variables were considered separately, all nine dependent variables reached significance (p < .001). Schizophrenia scored highest in all categories except blame and pity. Blame was the highest for binge eating and pity was the highest for intellectual disabilities. Efforts to reduce stigmatization must be tailored to each disorder.


Counseling For Psychosocial Stress Factors Associated With Hearing Loss, Emily Mcmaster Apr 2022

Counseling For Psychosocial Stress Factors Associated With Hearing Loss, Emily Mcmaster

Honors Theses

Audiologists play a major role in helping people with hearing loss learn how to better communicate and how to connect to the world around them. The purpose of this project investigates the extent to which audiologists counsel their clients for the psychosocial stress factors caused by hearing loss, along with determining the extent in which patients with hearing loss feel they would benefit from counseling services implemented into their appointments. In addition to psychosocial stress factors, the thesis will analyze the extent to which clients are educated on their hearing loss and given practical ways to adjust to their loss ...


A Meta-Analysis On The Differences In Neuroplasticity Between Women And Men After Traumatic Brain Injuries, Victoria A. Martin Apr 2022

A Meta-Analysis On The Differences In Neuroplasticity Between Women And Men After Traumatic Brain Injuries, Victoria A. Martin

Honors Theses

The current meta-analysis investigates the differences in neuroplasticity between women and men after a traumatic brain injury (TBI). Research on the differences in neuroplasticity between women and men is relatively new and few studies have reported outcome variables by gender after TBIs. Neuroplasticity is the brain’s ability to adapt and change particularly because of learning or brain injuries. TBI is a leading cause of death and disability worldwide; because of this, learning more about these differences can give scientists and clinicians more information on how to better treat people with brain injuries. Current research is inconsistent on whether there ...


Grasping The Intangible: The Perseverance Of Physical Music Media In A Digital World, Sam Youmans Apr 2022

Grasping The Intangible: The Perseverance Of Physical Music Media In A Digital World, Sam Youmans

Honors Theses

Music is a unique economic good with several interesting characteristics: as an art form, its value is immensely subjective and changes with the culture; it is most widely consumed via online streaming platforms but still embedded onto physical formats and sold through retailers; and the United States music business had to pivot through substantial economic disruption at the turn of the century with the advent of peer-to-peer file sharing. Given the digital world in which we live, this thesis explains why people still purchase music on physical formats. This is accomplished by discussing revenue data from the past few years ...


Developing Novel Water-Soluble Porphyrins For Potential Use As Photosensitizers In Photodynamic Therapy, Kayla R. Whittington Apr 2022

Developing Novel Water-Soluble Porphyrins For Potential Use As Photosensitizers In Photodynamic Therapy, Kayla R. Whittington

Honors Theses

Photodynamic therapy (PDT) is a treatment modality for various illnesses, including some types of cancer. Lung cancer is the leading cause of cancer death in the United States. The prevalence of lung cancer in certain gender, racial, ethnic, and socioeconomic groups add to existing health disparities in the United States. For this reason, it is necessary to address the social determinants underlying lung cancer disparities, as well as improve treatment options. These treatment options should be cost effective, convenient, and increase survival rates. This research focused on synthesizing novel water-soluble porphyrin compounds for use as photosensitive agents in PDT for ...


Rock Climbing Therapy For Individuals With Disabilities, Grace Loftin Apr 2022

Rock Climbing Therapy For Individuals With Disabilities, Grace Loftin

Honors Theses

This thesis explores what it means to be living with a disability, the background of cerebral palsy, and how participating in a climbing program can benefit these individuals and improve their quality of life. These advantages are discussed in detail and how further research on this topic may be conducted is expanded upon


Investigating The Efficacy Of Tazemetosttat For In Vitro Treatment Of Human Triple Negative Breast Cancer Cells, Harshita Indukuri Apr 2022

Investigating The Efficacy Of Tazemetosttat For In Vitro Treatment Of Human Triple Negative Breast Cancer Cells, Harshita Indukuri

Honors Theses

Cancer is a formidable, genetic disease that affects many people, either directly or indirectly. Breast cancer is the most commonly diagnosed cancer worldwide (31). Triple-negative breast cancer (TNBC) is a type of breast cancer that has a higher lethality compared to other breast cancers and has a poor prognosis due to its highly invasive nature and limited treatment options. Finding safe, effective, and accessible treatment for TNBC is integral to treating TNBC patients. Tazemetostat is an EZH2-inhibitor that has recently been approved for use in epithelioid sarcoma (23). EZH2 is an overexpressed protein in many cancers, including TNBC (11). However ...


Worse Exercise Habits And Diminished Body Image Perception In College Students, Is Covid-19 To Blame?, Lois Jeanette Anderson Apr 2022

Worse Exercise Habits And Diminished Body Image Perception In College Students, Is Covid-19 To Blame?, Lois Jeanette Anderson

Honors Theses

Early reports during the COVID-19 pandemic suggested that the public health safety measures associated with COVID-19 were creating negative consequences on individual’s physical and mental health (Huckins et al., 2020; Salazar de Pablo et al., 2020). These public health safety measures, including campus facility closures and limited capacities coupled with indoor mask-mandates, potentially influenced post-secondary students’ ability and/or willingness to participate in physical activity (PA). The purpose of this study was to explore the possible impact that COVID-19 had on body image perceptions among these students considering the predicted decrease in physical activity participation among the population. This ...


Exploring Risk Factors For Maternal Mortality: A Qualitative Study, Grace Lowe Apr 2022

Exploring Risk Factors For Maternal Mortality: A Qualitative Study, Grace Lowe

Honors Theses

Maternal mortality, the death of a woman during pregnancy or within one year of delivery, claims approximately 700 women annually in the United States. In Ohio, the rate is slightly less than 16 women each year. Knowledge and intervention of risk factors, particularly the non-medical factors for maternal mortality are crucial to preventing these deaths. This qualitative interview study with community health workers identified specific risk factors Ohio mothers face and how they are being addressed in the field by individuals who work directly with pregnant and postpartum women. The interviews uncovered various interventions that are recommended to reduce the ...


Evaluation Of Patellar Tendon Load Across Sports-Related Activities, Breven Perry Apr 2022

Evaluation Of Patellar Tendon Load Across Sports-Related Activities, Breven Perry

Honors Theses

Osgood Schlatter’s Disease (OSD) is a disease that results in a painful inflammation of the tibial tuberosity caused from overuse of the knee as the apophyseal growth plate is continuing to close in adolescence. As this condition arises from too much tension on a closing growth plate, it is most prevalent in children 8-15 years old, and especially common in athletes. The purpose of this study is to examine the peak patellar tendon force experienced from a variety of movements common in sport. 30 subjects performed a walk, run, hop, single-leg hop (SLH), countermovement jump (CMJ), single-leg CMJ, drop ...


The Role Of Socioeconomic Status In Cognition And Brain Health Across The Lifespan, Erica Chung Jan 2022

The Role Of Socioeconomic Status In Cognition And Brain Health Across The Lifespan, Erica Chung

Honors Theses

Disparities in cognition are inevitable throughout the lifespan due to socioeconomic gaps. Individuals of lower socioeconomic status (SES) may have fewer access to environmental resources, especially with regard to education, than individuals of higher socioeconomic status. Differences in available resources from a young age may affect brain development, leading to detriments in cognition and behavior, further impacting socioeconomic success in adulthood. In the present study, we modeled the development of the dorsolateral prefrontal cortex (DLPFC) and changes in cognitive function throughout the life trajectory in the Nathan Kline Institute for Psychiatric Research Rockland Sample. The DLPFC volume was predicted to ...


Examining The Healthcare Journeys Of African American Individuals With Type 2 Diabetes Amid Covid-19, Lei Edmerson Dec 2021

Examining The Healthcare Journeys Of African American Individuals With Type 2 Diabetes Amid Covid-19, Lei Edmerson

Honors Theses

The overall purpose of this study is to explore the pandemic experience of African American’s with Type 2 Diabetes. This study was done to highlight a specific group of people who live with a chronic illness and the steps they took to ensure their safety during a pandemic. The COVID- 19 pandemic had been shown to adversely and disproportionately impact minorities and those with diabetes in regards to mortality rates. This study aims to bring light to the stories of those dealing with more than just the pandemic. It wanted to explore how they made it thus far, and ...


An Investigation Of Chronic Pain As A Much-Neglected Symptom Of Hypermobile Ehlers-Danlos Syndrome, Sydney Collins Dec 2021

An Investigation Of Chronic Pain As A Much-Neglected Symptom Of Hypermobile Ehlers-Danlos Syndrome, Sydney Collins

Honors Theses

Ehlers Danlos Syndrome is a group of heritable loose connective tissue disorders with 13 distinguished subtypes. The hypermobile type of Ehlers Danlos Syndrome (hEDS) is the most common subtype and is caused by a genetic mutation that leads to defective collagen fibrils. This leads to joint instability and hypermobility, skin elasticity, widespread pain, fatigue, and generalized tissue fragility. Chronic pain is reported to be a symptom in as high as 92% of the hEDS population (Voermans et al., 2010); despite this prevalence, there is a significant lack of research, awareness, and treatment standardization regarding pain in hEDS. This literature review ...


A Literature Review Of Mild Traumatic Brain Injury Research, Brindlea Peterson Dec 2021

A Literature Review Of Mild Traumatic Brain Injury Research, Brindlea Peterson

Honors Theses

Mild traumatic brain injuries (mTBI) are a type of traumatic brain injury (TBI) usually sustained from an injury to the head and are hard to diagnose due to the lack of physical evidence seen in diagnostic radiology. The estimated worldwide rate of incidence each year is 42 million, making mTBIs rather common. In the US armed forces, that rate of incidence is even higher due to the dangerous nature of the work being done. Many complications can come from not properly addressing an mTBI after it happens which makes being able to determine an appropriate return-to-play or return-to-duty time very ...


Barriers Of Bronson School Of Nursing Program, Karla Kline Dec 2021

Barriers Of Bronson School Of Nursing Program, Karla Kline

Honors Theses

Aside from the rigorous coursework of nursing school, nursing students experience various barriers that impact their academic success. Barriers to successful completion of traditional Bachelor of Science of Nursing (BSN) programs include isolation, lack of peer connections, lack of faculty connections, lack of family support, lack of financial support, and mental health struggles (Shaw, 2015) (Seal & Woods, 2021). This research will aim at assessing and exploring these barriers students are facing, along with the additional or exacerbated barriers the COVID-19 pandemic has surfaced.

This study will expand on the research conducted by Shaw (2015), in which she examined the barriers ...


The Effect Of Twist1b And Twist2 Knockdown On Tgf-Beta Signaling Expression In Tendon Progenitors, Marinia N. Bishay Dec 2021

The Effect Of Twist1b And Twist2 Knockdown On Tgf-Beta Signaling Expression In Tendon Progenitors, Marinia N. Bishay

Honors Theses

Somites are important mesoderm structures that form in regularly timed intervals from the anterior end of the paraxial mesoderm at the end of gastrulation during embryogenesis. Cells of the ventromedial portion of the somite, the sclerotome, undergo epithelial to mesenchymal transition, surround the notochord, and give rise to connective tissues of the axial skeleton including the vertebrae, tendons, and ligaments. We are interested in understanding how the sclerotome is compartmentalized into the region that makes tendons. Genes expressed in the sclerotome, twist1 and twist2, are likely involved in the downstream differentiation of sclerotome to tendon progenitors. Previous studies have shown ...


Assessing The Impact Of Covid-19 Restrictions On The Perinatal Experience In Mississippi, Baylee Grimsley Dec 2021

Assessing The Impact Of Covid-19 Restrictions On The Perinatal Experience In Mississippi, Baylee Grimsley

Honors Theses

The purpose of this study is to assess how COVID-19 restrictions affected the perinatal experience of women in Mississippi. A flyer detailing the purpose and inclusion criteria of the study was sent via social media platforms. Five postpartum women from the Hattiesburg, Mississippi area participated in this study. Eight open-ended questions were asked in an interview format, and a seven-question demographic survey was given to each participant at the conclusion of the interview. Five restrictions related to COVID-19 were identified: visitor restrictions in the hospital, mask requirements in healthcare facilities, screening of patients upon admission to the Labor and Delivery ...


Examining An Intersection Of Environmental Justice And Covid-19 Risk Assessment: A Review, Ashley Ellis Dec 2021

Examining An Intersection Of Environmental Justice And Covid-19 Risk Assessment: A Review, Ashley Ellis

Honors Theses

This study views the risks associated with the novel coronavirus (COVID-19) as an environmental injustice issue due to the connection between existing environmental disparities and the disproportional negative impacts brought upon by the virus. The social and health determinants attributed to those environmental disparities have traditionally been evaluated as individual risk factors, an approach that fails to gauge the complexity of an environmental injustice issue. This study employs the emerging theory of intersectionality, a belief that phenomena cannot be linked to one principal cause but instead an interconnected web of influences, in order to synthesize the multitude of factors believed ...


The State Of Healthcare Policy Education In Nursing School Curricula: A Literature Review, Katelyn Gebelein Dec 2021

The State Of Healthcare Policy Education In Nursing School Curricula: A Literature Review, Katelyn Gebelein

Honors Theses

The purpose of this paper was to conduct a literature review regarding the current state of health policy education in nursing school curricula. Additionally, the paper will outline what improvements are being implemented in nursing education. The database CINAHL was used to conduct this study. According to the literature, there are an inadequate number of nurses participating in health policy reform which can be linked back to a lack of health policy education while in nursing school. The literature suggests options such as experiential learning, group activities and reflections, enhancing faculty knowledge, suggesting new teaching strategies, and implementing new courses ...


Increased Incidence Of Substance Use And Substance Use Disorders Among Mexicans That Have Migrated To The United States, Emily Hock Aug 2021

Increased Incidence Of Substance Use And Substance Use Disorders Among Mexicans That Have Migrated To The United States, Emily Hock

Honors Theses

The United States is becoming increasingly older and more racially and ethnically diverse, with Mexican Americans adults aged 65 and over becoming the frontrunners in population growth. Substance use disorders are high among this particular population, with alcohol and tobacco being the most common culprits. Previous research suggests that the prevalence of drinking and smoking among Mexican Americans is increased compared to Mexicans living in Mexico, and substance use rates are highest in those most accustomed to United States culture. While acculturation may initially increase exposure to healthcare options, Mexican Americans are disproportionally uneducated and have lower socioeconomic status than ...


Environmental Justice Analysis Of Drinking Water Policies In Michigan Cities, Annika Paldan Jul 2021

Environmental Justice Analysis Of Drinking Water Policies In Michigan Cities, Annika Paldan

Honors Theses

This thesis examined environmental justice aspects of drinking water policies in four cities across Michigan: Flint, Birmingham, St. Joseph, and Benton Harbor. An overview of the history of the environmental justice movement, environmental racism, and drinking water policies provided the basis for a four-part evaluative criterion to assess environmental justice components at the municipal level. These criteria include (1) housing tenure, (2) age, size, and service line composition of the infrastructure, (3) public participation in the policy process, and (4) emergency management of the city. Findings indicate that environmental justice has come a long way, with cities now incorporating components ...


Literature Review Of Human Hdr Syndrome With Gata3 Haplo Insufficiency, Olivia Ambursley-Gries Jun 2021

Literature Review Of Human Hdr Syndrome With Gata3 Haplo Insufficiency, Olivia Ambursley-Gries

Honors Theses

This literature mining project is regarding mutations that cause hearing loss in patients with human hypo parathyroid, deafness, and renal dysplasia (HDR) syndrome caused by a mutation in the GATA3 gene. The disease is unique; not all diagnosed individuals present with all symptoms of the triad. Van Esh et al. found that the haploinsufficiency of the GATA3 is found on chromosome 10p14-p15 (ref.1). The focus of this work is to condense the literature on GATA3 haploinsufficiency correlating to human HDR syndrome. Due to the lack of global healthcare access, it can be assumed that many cases remain undiagnosed; 180 ...


Female Infertility In The United States And India: An Analysis Of Treatment Barriers And Coping Strategies, Devneet Singh Jun 2021

Female Infertility In The United States And India: An Analysis Of Treatment Barriers And Coping Strategies, Devneet Singh

Honors Theses

This research studies barriers to accessing fertility treatment in the United States (U.S.) and India, as well as the coping strategies infertile women use. Barriers include reproductive health knowledge, cost, and politics, while coping is affected by cultural stigma, family, and religion. These two countries were chosen for their different cultural contexts, healthcare systems, and political infrastructure. Ten fertility specialists across both countries were interviewed as expert informants. Reproductive health knowledge was the most important barrier to accessing care in both countries, with similar gaps in understanding when and what type of care to utilize, though social media can ...


Developing Prediction Models For Kidney Stone Disease, Joseph Palko Jun 2021

Developing Prediction Models For Kidney Stone Disease, Joseph Palko

Honors Theses

Kidney stone disease has become more prevalent through the years, leading to high treatment cost and associated health risks. In this study, we explore a large medical database and machine learning methods to extract features and construct models for diagnosing kidney stone disease.

Data of 46,250 patients and 58,976 hospital admissions were extracted and analyzed, including patients’ demographic information, diagnoses, vital signs, and laboratory measurements of the blood and urine. We compared the kidney stone (KDS) patients to patients with abdominal and back pain (ABP), patients diagnosed with nephritis, nephrosis, renal sclerosis, chronic kidney disease, or acute and ...


A Case For Early Intervention Speech Therapy For All Children In The Foster Care System, Moriah Manchack May 2021

A Case For Early Intervention Speech Therapy For All Children In The Foster Care System, Moriah Manchack

Honors Theses

A look into the need for Early Intervention speech therapy services for children in the foster care system, as well as the laws and provisions for these services.