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2001

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Articles 1 - 30 of 1649

Full-Text Articles in Medicine and Health Sciences

Will Theaters Receive Two Thumbs Up From Individuals With Disabilities?, Joseph H. Huber Dec 2001

Will Theaters Receive Two Thumbs Up From Individuals With Disabilities?, Joseph H. Huber

Movement Arts, Health Promotion and Leisure Studies Faculty Publications

No abstract provided.


Systems Analysis Projects In Advanced Nursing Practice Education, Barfield John, Debra Smith, Maribeth Smith Dec 2001

Systems Analysis Projects In Advanced Nursing Practice Education, Barfield John, Debra Smith, Maribeth Smith

The Corinthian

The purpose of the presentation is to stimulate discussion among nursing educators regarding integration of an educational strategy which can enhance the ability of graduate students to analyze clinical and administrative problems.


Genes Encoding Several Poly (Adp-Ribose) Glycohydrolase (Parg) Enzymes, The Proteins And Fragments Thereof, And Antibodies Immnoreactive Therewith, Myron Jacobson, Elaine L. Jacobson, Jean-Christoph Amé, Winston Lin Dec 2001

Genes Encoding Several Poly (Adp-Ribose) Glycohydrolase (Parg) Enzymes, The Proteins And Fragments Thereof, And Antibodies Immnoreactive Therewith, Myron Jacobson, Elaine L. Jacobson, Jean-Christoph Amé, Winston Lin

Graduate Center for Nutritional Sciences Faculty Patents

The isolation and characterization of cDNAs encoding poly(ADP-ribose) glycohydrolase (PARG) enzymes and the amino acid sequences of PARGs from several species are described. PARG is involved in the cellular response to DNA damage and its proper function is associated with the body's response to neoplastic disorder inducing agents and oxidative stress. Expression vectors containing the cDNAs and cells transformed with the vectors are described. Probes and primers that hybridize with the cDNAs are described. Expression of the cDNA in E. coli results in an enzymatically active protein of about 111 kDa and an active fragment of about 59 kDa. Methods …


What's Happening: December 19, 2001, Maine Medical Center Dec 2001

What's Happening: December 19, 2001, Maine Medical Center

What's Happening

No abstract provided.


Going Global The Fastest Way To The Top, Rick Burton Dec 2001

Going Global The Fastest Way To The Top, Rick Burton

Sport Management - All Scholarship

No abstract provided.


Effect Of Seeing Tobacco Use In Films On Trying Smoking Among Adolescents: Cross Sectional Study, James D. Sargent, Michael L. Beach, Madeline A. Dalton, Leila A. Mott, Jennifer J. Tickle, M. Bridget Ahrens, Todd F. Heatherton Dec 2001

Effect Of Seeing Tobacco Use In Films On Trying Smoking Among Adolescents: Cross Sectional Study, James D. Sargent, Michael L. Beach, Madeline A. Dalton, Leila A. Mott, Jennifer J. Tickle, M. Bridget Ahrens, Todd F. Heatherton

Dartmouth Scholarship

Objective: To test the hypothesis that greater exposure to smoking in films is associated with trying smoking among adolescents.


Nipple Aspirate Cytology And Pathologic Parameters Predict Residual Cancer And Nodal Involvement After Excisional Breast Biopsy., E R Sauter, H Ehya, A Mammen, G Klein Dec 2001

Nipple Aspirate Cytology And Pathologic Parameters Predict Residual Cancer And Nodal Involvement After Excisional Breast Biopsy., E R Sauter, H Ehya, A Mammen, G Klein

Department of Surgery Faculty Papers

We previously demonstrated that abnormal nipple aspirate fluid (NAF) cytology predicted residual breast cancer (RC) and tumour size after excisional biopsy (EB), although normal NAF cytology did not exclude RC. Tumour size correlates with the risk of lymph node (LN) metastases. LN metastases provide prognostic information allowing medical and radiation oncologists to determine the need for adjuvant therapy. We hypothesized that pathologic factors known after EB, combined with NAF cytology, would predict with a high degree of accuracy the presence of RC and LN spread. NAF cytology and pathologic parameters: tumour distance from biopsy margins, multifocal and multicentric disease, sub-type …


Neonatal Pain Management: The Evaluation Of Two Methods On Educating Neonatal Nurses, Jacqueline Jupin Manzi Dec 2001

Neonatal Pain Management: The Evaluation Of Two Methods On Educating Neonatal Nurses, Jacqueline Jupin Manzi

Seton Hall University Dissertations and Theses (ETDs)

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Vdac-Dependent Permeabilization Of The Outer Mitochondrial Membrane By Superoxide Induces Rapid And Massive Cytochrome C Release., M Madesh, György Hajnóczky Dec 2001

Vdac-Dependent Permeabilization Of The Outer Mitochondrial Membrane By Superoxide Induces Rapid And Massive Cytochrome C Release., M Madesh, György Hajnóczky

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Enhanced formation of reactive oxygen species (ROS), superoxide (O2*-), and hydrogen peroxide (H2O2) may result in either apoptosis or other forms of cell death. Here, we studied the mechanisms underlying activation of the apoptotic machinery by ROS. Exposure of permeabilized HepG2 cells to O2*- elicited rapid and massive cytochrome c release (CCR), whereas H2O2 failed to induce any release. Both O2*- and H2O2 promoted activation of the mitochondrial permeability transition pore by Ca2+, but Ca2+-dependent pore opening was not required for O2*--induced CCR. Furthermore, O2*- alone evoked CCR without damage of the inner mitochondrial membrane barrier, as mitochondrial membrane potential …


Individual Differences In Behavioral Responses To Novelty And Amphetamine Self-Administration In Male And Female Rats, J. E. Klebaur, Rick A. Bevins, T. M. Segar, M. T. Bardo Dec 2001

Individual Differences In Behavioral Responses To Novelty And Amphetamine Self-Administration In Male And Female Rats, J. E. Klebaur, Rick A. Bevins, T. M. Segar, M. T. Bardo

Department of Psychology: Faculty Publications

Previous work has shown that individual differences in locomotor activity in an inescapable novel environment can predict acquisition of amphetamine self-administration. The current study examined whether individual differences in approach to novelty in a free choice test could also predict amphetamine self-administration. Further, the current study examined whether individual differences in either free choice or inescapable novelty tests could predict responding for a nondrug reinforcer (sucrose) in the presence and absence of amphetamine. Male and female rats were first tested for their response to free choice novelty (playground maze and novelty-induced place preference tests) and inescapable novelty. They were then …


A Pdz-Binding Motif Is Essential But Not Sufficient To Localize The C Terminus Of Cftr To The Apical Membrane, Michal I. Milewski, John E. Mickle, John K. Forrest, Diane M. Stafford, Bryan D. Moyer, Jie Cheng, William B. Guggino, Bruce A. Stanton, Garry R. Cutting Dec 2001

A Pdz-Binding Motif Is Essential But Not Sufficient To Localize The C Terminus Of Cftr To The Apical Membrane, Michal I. Milewski, John E. Mickle, John K. Forrest, Diane M. Stafford, Bryan D. Moyer, Jie Cheng, William B. Guggino, Bruce A. Stanton, Garry R. Cutting

Dartmouth Scholarship

Localization of ion channels and transporters to the correct membrane of polarized epithelia is important for vectorial ion movement. Prior studies have shown that the cytoplasmic carboxyl terminus of the cystic fibrosis transmembrane conductance regulator (CFTR) is involved in the apical localization of this protein. Here we show that the C-terminal tail alone, or when fused to the green fluorescent protein (GFP), can localize to the apical plasma membrane, despite the absence of transmembrane domains. Co-expression of the C terminus with full-length CFTR results in redistribution of CFTR from apical to basolateral membranes, indicating that both proteins interact with the …


What's Happening: December 5, 2001, Maine Medical Center Dec 2001

What's Happening: December 5, 2001, Maine Medical Center

What's Happening

No abstract provided.


Anger, Child Behavior, And Family Distress: Further Evaluation Of The Parental Anger Inventory, Georganna Sedlar, David J. Hansen Dec 2001

Anger, Child Behavior, And Family Distress: Further Evaluation Of The Parental Anger Inventory, Georganna Sedlar, David J. Hansen

Department of Psychology: Faculty Publications

Presumably, anger is a common experience of parenting. Although practitioners and researchers recognize the role of anger in various parenting situations, objective and standardized measures of parental anger have been notably lacking in the field. This study examined the Parental Anger Inventory (PAI), a measure developed specifically to assess parental anger in response to child misbehavior. A diverse sample of 98 parents participated in the study, including (a) physically abusive or neglectful parents, or both, n = 44; (b) nonmaltreating clinic parents seeking assistance for child behavior problems, n = 24; and (c) nonmaltreating, non–help-seeking community parents, n = 30. …


Analysis Of Mitotic Microtubule-Associated Proteins Using Mass Spectrometry Identifies Astrin, A Spindle-Associated Protein, Gary J. Mack, Duane A. Compton Dec 2001

Analysis Of Mitotic Microtubule-Associated Proteins Using Mass Spectrometry Identifies Astrin, A Spindle-Associated Protein, Gary J. Mack, Duane A. Compton

Dartmouth Scholarship

We purified microtubules from a mammalian mitotic extract and obtained an amino acid sequence from each microtubule-associated protein by using mass spectrometry. Most of these proteins are known spindle-associated components with essential functional roles in spindle organization. We generated antibodies against a protein identified in this collection and refer to it as astrin because of its association with astral microtubule arrays assembled in vitro. Astrin is approximately 134 kDa, and except for a large predicted coiled-coil domain in its C-terminal region it lacks any known functional motifs. Astrin associates with spindle microtubules as early as prophase where it concentrates at …


Genetic Dissection Of Behavioral And Neurogenomic Responses To Acute Ethanol, Aaron Wolen Dec 2001

Genetic Dissection Of Behavioral And Neurogenomic Responses To Acute Ethanol, Aaron Wolen

Theses and Dissertations

Individual differences in initial sensitivity to ethanol are strongly related to the heritable risk of alcoholism in humans. To elucidate key molecular networks that modulate ethanol sensitivity we performed a systems genetics analysis of ethanol-responsive gene expression in brain regions of the mesocorticolimbic reward circuit (prefrontal cortex, nucleus accumbens and ventral midbrain) across the BXD RI panel, a highly diverse family of isogenic mouse strains before and after treatment with ethanol. Acute ethanol altered the expression of ~2,750 genes in one or more regions and 400 transcripts were jointly modulated in all three. Ethanol-responsive gene networks were extracted with a …


Pretreatment Characteristics Of Legally Coerced Drug Treatment Seekers, Bridgett Augustino Dec 2001

Pretreatment Characteristics Of Legally Coerced Drug Treatment Seekers, Bridgett Augustino

Masters Theses & Specialist Projects

This study examines the sociodemographics, drug use, criminal, and treatment histories of 598 residential and outpatient legally coerced drug treatment seekers in the Kentucky Treatment Outcome and Performance Pilot Studies Enhancement Project. Analyses examined whether users/addicts entering chemical dependency treatment under legal coercion differed from nonlegally coerced treatment seekers. Stanley Cohen's theoretical model of social control provided the theoretical framework for the study. Results showed demographic and behavioral differences were noted between respondents under no coercion and those under legal coercion on gender, age, educational status, pretreatment criminality and current treatment modality. In addition, differences between the legally coerced and …


The Effect Of Lead Acetate On The Susceptibility Of C3heb/Fej Mice Infected With The Parasite Trypanosoma Cruzi, Savonna Warren Dec 2001

The Effect Of Lead Acetate On The Susceptibility Of C3heb/Fej Mice Infected With The Parasite Trypanosoma Cruzi, Savonna Warren

Masters Theses & Specialist Projects

Lead has been mined by man for centuries with evidence of its use dating back 6000 years. Chronic exposure to lead can result in encephalopathy, anemia, and nephropathy. Today, cases of lead poisoning are uncommon; however, lead continues to be incorporated into the body through subclinical exposures. These low dosages of lead have been shown to have a deleterious effect on the immune system. Experimental animals exposed to low levels of lead are unable to effectively respond to a number of bacterial and viral challenges. The present study focuses on the relationship between lead and parasitic infection. Parasitemia, mortality, serum …


Effects Of Antioxidant Supplementation With Vitamin E And Selenium On Cytokine Production In Mice Infected With Trypanosoma Cruzi, Dong Chen Dec 2001

Effects Of Antioxidant Supplementation With Vitamin E And Selenium On Cytokine Production In Mice Infected With Trypanosoma Cruzi, Dong Chen

Masters Theses & Specialist Projects

Dietary supplementation with the antioxidants vitamin E and selenium (Se) has been shown to be beneficial against the intracellular parasite Trypanosoma cruzi during experimental Chagas' disease. Supplementation of mice with vitamin E and selenium at levels well above the recommended daily allowance for these two substances results in significantly decreased parasitemia levels and increased longevity. However, the mechanistic role of the antioxidants in this process is not well understood. It is known that vitamin E and selenium can reduce oxidative stress and improve host immune responses. In addition, the synthesis of many regulatory cytokines is known to be influenced by …


Evaluation Of Directly Observed Therapy In Pulmonary Tuberculosis Patients In Nepal: Treatment Outcome And Patient Compliance, Baishali Bhattacharya Dec 2001

Evaluation Of Directly Observed Therapy In Pulmonary Tuberculosis Patients In Nepal: Treatment Outcome And Patient Compliance, Baishali Bhattacharya

Masters Theses & Specialist Projects

Tuberculosis is the leading cause of infectious disease in Nepal. An estimated 60% of the adult population aged between 15-45 years is infected with tuberculosis, and 45% of the total population is infected. Ten percent of people infected with TB progress to active disease. To combat tuberculosis, Directly Observed Therapy (DOT) was adopted in Nepal in 1996. DOT was administered at four national demonstration sites in 1996 and expanded over time so that 56% of the population to date have been covered by DOT. This study aimed to evaluate DOT in pulmonary TB patients in Nepal in terms of patient …


Inheritance Of Dorsal Fin Coloration In The Metriaclima Species Complex (Teleostei: Cichlidae) Of Lake Malawi, Paulette Reneau Dec 2001

Inheritance Of Dorsal Fin Coloration In The Metriaclima Species Complex (Teleostei: Cichlidae) Of Lake Malawi, Paulette Reneau

Masters Theses & Specialist Projects

The rock-dwelling cichlids (mbuna) of Lake Malawi have undergone an explosive evolution, giving rise to an assemblage of 300-500 species within the last one million years. Most widespread mbuna 'species' are characterized by the presence of local endemic populations, differing primarily in coloration and often of uncertain taxonomic rank. The recency and rapidity of speciation within the mbuna have led to difficulties in reconstructing an accurate species-level phylogeny, in turn limiting our ability to elucidate the evolutionary dynamics associated with divergence of coloration and other characters. Based on morphometric and meristic characters, Stauffer et al. (1997) erected a new genus …


Predictors Of Injury From Fighting Among Adolescent Males, B J. Hammig, L L. Dahlberg, Monica H. Swahn Dec 2001

Predictors Of Injury From Fighting Among Adolescent Males, B J. Hammig, L L. Dahlberg, Monica H. Swahn

Public Health Faculty Publications

Objectives: To identify violence related behaviors associated with injuries among adolescent males involved in fights.

Methods: Data from the National Longitudinal Study of Adolescent Health were used to develop weighted estimates of injury prevalence and associations between injury and violence related behaviors.

Results: Forty seven per cent injured others and 18% were themselves injured in a fight among adolescent males in the preceding 12 months. Group fighting, fighting with strangers, and weapon use were predictive of injury in this sample.

Conclusions: These findings suggest that injuries associated with fighting are a health risk among adolescent males. Certain behaviors, such as …


Beta-Adrenergic, Arachidonic Acid And Potassium Channel Associated-Regulation Of Human Breast Cancer Cell Lines, Yavuz Cakir Dec 2001

Beta-Adrenergic, Arachidonic Acid And Potassium Channel Associated-Regulation Of Human Breast Cancer Cell Lines, Yavuz Cakir

Doctoral Dissertations

During the late stages of breast cancer progression, breast cancer cell growth switches from steroid hormone to growth factor dependence, and it is assumed that invasive breast cancers are growth factor receptor positive and estrogen hormone resistant. The cellular arachidonic acid (AA) pathway is upregulated in a variety of cancer types, and it may play an important role in the growth regulation of breast cancer cells.

Recent evidence suggests that beta-adrenergic receptors (β-ARs) are expressed in some estrogen receptor (ER) negative breast cancers and that beta agonists not only can trigger AA release via the activation of cytosolic PLA2 or …


Expression And Characterization Of The Mhc Class Ii Transactivator In K-562 Cells, Noel Elyssa Day Dec 2001

Expression And Characterization Of The Mhc Class Ii Transactivator In K-562 Cells, Noel Elyssa Day

Doctoral Dissertations

The K-562 cell line was developed from the pleural effusion of a patient with chronic myelogenous leukemia (CML) in blast crisis and has served as an excellent model to study the properties of CML cells. The highly undifferentiated cells can be induced by a variety of chemicals to follow multiple pathways of differentiation. When K-562 cells were treated with phorbol myristate acetate (PMA), they exhibited accessory cell functions by replacing monocytes in the activation of resting Th2 lymphocytes. However, K-562 cells are negative for the expression of class II major histocompatibility complex (MHC) antigens HLA-DR, -DP, and -DQ. The focus …


Effects Of Maternal Employment And Prematurity On Child Outcomes In Single Parent Families, Joanne M. Youngblut, Dorothy Brooten, Lynn T. Singer, Theresa Standing, Haejung Lee, Willard L. Rodgers Dec 2001

Effects Of Maternal Employment And Prematurity On Child Outcomes In Single Parent Families, Joanne M. Youngblut, Dorothy Brooten, Lynn T. Singer, Theresa Standing, Haejung Lee, Willard L. Rodgers

Nicole Wertheim College of Nursing and Health Sciences

Background

Effects of maternal employment for preschool children vary based on specific characteristics of the mother’s employment, the family’s economic status, and the mother’s attitudes about employment. However, there is limited research on a growing group of children at developmental risk—those born prematurely and living in a single-parent family.

Objective

To examine the effects of maternal employment and prematurity on child cognition and behavior in single-parent families.

Methods

Sixty preterm and 61 full-term preschool children were recruited through NICU admission records and birth records. Data were collected with the Kaufmann Assessment Battery for Children, Peabody Picture Vocabulary Test, Child Behavior …


Expression Of Gus Gene In Tobacco (Nicotiana Tabacum) And Corn (Zea Mays) Using Dimboa-Resistant Agrobacterium Strains, Deepti Mohamalawari Dec 2001

Expression Of Gus Gene In Tobacco (Nicotiana Tabacum) And Corn (Zea Mays) Using Dimboa-Resistant Agrobacterium Strains, Deepti Mohamalawari

Masters Theses & Specialist Projects

This thesis evaluates the ability of Agrobacterium tumefaciens strains resistant to the compound DIMBOA [2, 4-dihydroxy-7-methoxy-2h-l,4- benzoxazin-3(4H)-one] to infect corn. DIMBOA is a secondary plant metabolite and is believed to have antimicrobial properties and provides resistance to the plant against microbial infection. Agrobacteriummediated genetic transformation technique can be employed to genetically alter most dicotyledonous plant species. However, such transformation has been limited in monocotyledonous plants, especially corn. One of the factors responsible for this recalcitrance is the presence of DIMBOA in corn shoots. In this study, we proposed the use of DIMBOA- resistant strains of Agrobacterium tumefaciens, bearing binary plasmids …


Temporal, Perspectives, Dispositional Styles, And Subjective Well-Being, Mary Naeger Dec 2001

Temporal, Perspectives, Dispositional Styles, And Subjective Well-Being, Mary Naeger

Masters Theses & Specialist Projects

This study investigated the relationship between time perspective (TP) and the personality dispositions of optimism, pessimism, and realism with regard to their proposed influence on three measures that collectively assessed subjective well-being (SWB). The Depression-Happiness Scale (McGreal & Joseph, 1993) assessed happiness or the presence of positive affect and the absence of negative affect, the cognitiveaffective components of SWB. The Satisfaction with Life Scale (SWLS) (Diener, Emmons, Larsen, & Griffin, 1985) provided the measurement of subjective life satisfaction, the essential final cognitive-judgmental component of SWB. The Life Orientation Scale-Revised (LOT-R) (Scheier, Carver, and Bridges, 1994) and a Reality Scale, composed …


The Research Of Medical Service Quality Evaluation: From The Viewpoint Of Predicting Reclaimed Rate Using Neural Networks, Horng-Jeng Shyu, Chao-Chang Chiu, Pei-Lun Hsu, Meei-Fang Lin Dec 2001

The Research Of Medical Service Quality Evaluation: From The Viewpoint Of Predicting Reclaimed Rate Using Neural Networks, Horng-Jeng Shyu, Chao-Chang Chiu, Pei-Lun Hsu, Meei-Fang Lin

Rehabilitation Practice and Science

The goal of this study was to investigate the subtle interrelationships between the insurance claim’s data and clinic performance of medical institutes. Because the medical claims data increase drastically, the review efforts and processes become rather complex and inefficient. The physicians of review committee should have an enterprise view of the claims.We create the performance indicators from consistent data & meta data established from the clinic performance of medical institutes. We adopted 16 outpatient review indicators. We collected rehabilitation claims in middle branch of NHIB since July 1996 till Feb 1997. The prediction model created using both the neural network …


Lumbar Disc Herniation Along With Ruptured Abdominal Aortic Aneurysm: A Casereport And Literature Review, Woan-Chwen Wu, Chen-Liang Chou, Ming-Chi Yung, Shing-Su Chen, Tcho-Jen Liu, Rai-Chi Chan Dec 2001

Lumbar Disc Herniation Along With Ruptured Abdominal Aortic Aneurysm: A Casereport And Literature Review, Woan-Chwen Wu, Chen-Liang Chou, Ming-Chi Yung, Shing-Su Chen, Tcho-Jen Liu, Rai-Chi Chan

Rehabilitation Practice and Science

Abdominal aortic aneurysm is a condition affecting nearly 4% of the elderly population. It has a potential for producing a wide range of symptoms, including abdominal pain and back pain. It is rare that abdominal aortic aneurysm presents with paraplegia. From literature review there have been very few reports of patients who sustained lumbar disc herniation along with ruptured abdominal aortic aneurysm. We reported a 68-year-old man with a previously undiagnosed abdominal aortic aneurysm presenting with acute paraplegia. This patient had a history of lumbar disc herniation and was receiving pelvic traction. He survived after operation, but some long-term sequelae, …


Mapping Of Cortical Motor Reorganization In Spinal Cord Injury, Leonid Rozhkov Dec 2001

Mapping Of Cortical Motor Reorganization In Spinal Cord Injury, Leonid Rozhkov

Theses and Dissertations (ETD)

The annual incidence of spinal cord injury (SCI), not including those who die at the scene of the accident, is approximately 10,000 new cases in the United States. SCI, in its best outcome, may partially and temporarily disconnect the spinal cord from the brain. Some neuronal pathways remain intact in most S CI individuals, whose recovery depends on the utilization of the surviving connections. There is a change in the control of voluntary movements of the extremities by the cerebral cortex of the brain following spinal cord injury.

The technology of high-resolution EEG co-registered with MRI was applied to non-invasively …


Using An Importance-Performance Analysis Of Summer Students In The Evaluation Of Student Health Services., Candice Cline Duvernois Dec 2001

Using An Importance-Performance Analysis Of Summer Students In The Evaluation Of Student Health Services., Candice Cline Duvernois

Electronic Theses and Dissertations

Hitherto, students have not evaluated the importance and performance of services provided by the student health service (SHS) at East Tennessee State University. An evaluation could provide valuable feedback to providers and administration.

In 2001, there were 944 student visits in the summer sessions. Approximately 256 students were offered a survey containing an Importance-Performance scale of which 151 (59.0%) responded. The I-P scale rates the importance students place on healthcare services and the performance of the SHS in delivering services (i.e., patient satisfaction).

Based on mean scores, students reported high importance, high performance on urgent care, pharmacy and patient education. …