Medicine and Health Sciences Commons^™

Quality Of Life And Well-Being Of Breast Cancer Patients While Following A Breast Cancer-Related Lymphedema Surveillance Protocol, Madisen L. Prasek

Occupational Therapy Capstone Presentations

With breast cancer being one of the most common cancers in women globally and treatments being one of the greatest risk factors for secondary lymphedema (Eaton et al., 2020; He et al., 2023; Jørgensen et al., 2021), it is essential to understand how a breast cancer diagnosis and treatments affect an individual’s quality of life (QoL) and well-being. This capstone project aimed to gain in-depth clinical skills in lymphedema care, specifically in breast-care related lymphedema (BCRL), and educate on the psychosocial needs of the breast cancer population, with an emphasis on how being at risk for or diagnosed with BCRL …

Tunable Dual-Phase Dual-Drug Delivery System Using A Plga Microparticle/Pva Hydrogel Composite, Timothy John Eck

Theses and Dissertations

Current drug-eluting coatings have demonstrated controlled long-term, sustained release but have only tried to mitigate short-term burst release as a negative side effect. For applications like wound healing, there is a need for a drug-eluting coating which is adjustable in both short- and long-term release, independent of each other. We present a tunable dual-phase dual-drug delivery coating composed of drug-loaded polymer microparticles and drug-loaded hydrogel which can control short term and long term release individually in this study. This coating was created using lidocaine and dexamethasone encapsulated in poly(D,L-lactide-co-glycolide) particles combined with lidocaine- and dexamethasone-loaded poly(vinyl alcohol) hydrogel. Hydrogel drug …

Type 2 Diabetes Health Beliefs Of College Students, Emily Spindler

Honors College Theses

College students of health-related majors are sometimes assumed to have greater health literacy. The belief can be attributed to the students taking classes discussing health problems, diseases, risk factors, medical management, nutrition, and exercise. How often the health classes discuss type 2 diabetes (T2D) remains undetermined; therefore, the amount of knowledge and beliefs health students have of T2D is unknown. The objective of the study was to examine the relationship between students' majors, health beliefs about T2D, and engagement in behavioral risk factors at a mid-size regional public university. A quantitative, non-experimental, survey design was chosen, and responses were obtained …

To Decipher Genomic Evolution Of Dengue Virus And To Probe The Activation Mechanism Of A Her2 Directed Chimeric Antigen Receptor Toward Computer Aided Drug Design (Cadd), Mariya Hryb

Theses and Dissertations

This study encompasses three significant chapters focusing on diverse yet interconnected aspects of pharmaceutical research. Chapter 1 delves into the complexities of drug development, emphasizing the challenges and the pressing need for advanced technologies to streamline the process. Computational methods like Computer-Aided Drug Design (CADD) extend their scope beyond small molecules, aiding in the design of intricate biomolecules vital for biomedical advancements, especially in immunotherapy. Chapter 2 introduces the Near-Neutral Balanced Selectionist Theory (NNBST) validated through analysis of Dengue virus evolution. The unique features observed align with NNBST, surpassing existing theories. This approach offers a deeper understanding of viral evolution …

Implementing The Phq-9 Tool To As A Standard Of Practice In A Mental Health Setting: A Quality Improvement Project, Gabriella Laferriere

DNP Projects

The objective of this project was to implement the Patient Health Questionaire-9 (PHQ-9) tool as a standardized protocol for depression screening on patients being treated at an outpatient mental health facility in Central Connecticut, where there was no depression screening protocol in place. The clinical question being asked was, is there any correlation between use of the PHQ-9 tool and changes being made to a patient’s depression treatment plan?

Methods: A data collection form was completed by the psychiatric nurse practitioner on each patient who met the following criteria: Depression and/or anxiety was the patient’s primary diagnosis and patient was …

Impact Of Sars-Cov-2 Infection On Long-Term Depression Symptoms Among Veterans., Jason I. Chen, David Bui, Theodore J. Iwashyna, Troy A. Shahoumian, Alex Hickok, Megan Shepherd-Banigan, Eric J. Hawkins, Jennifer Naylor, Diana J. Govier, Thomas F. Osborne, Valerie A. Smith, C Barrett Bowling, Edward J. Boyko, George N. Ioannou, Matthew L. Maciejewski, Ann M. O'Hare, Elizabeth M. Viglianti, Amy S-B Bohnert, Denise M. Hynes

OHSU-PSU School of Public Health Faculty Publications and Presentations

Prior research demonstrates that SARS-COV-2 infection can be associated with a broad range of mental health outcomes including depression symptoms. Veterans, in particular, may be at elevated risk of increased depression following SARS-COV-2 infection given their high rates of pre-existing mental and physical health comorbidities. However, few studies have tried to isolate SARS-COV-2 infection associations with long term, patient-reported depression symptoms from other factors (e.g., physical health comorbidities, pandemic-related stress).

Novel Jak Inhibitors To Reduce Graft-Versus-Host Disease After Allogeneic Hematopoietic Cell Transplantation In A Preclinical Mouse Model, Sena Kim, Peter Ruminski, Megh Singh, Karl Staser, Kidist Ashami, Julie Ritchey, Sora Lim, John F Dipersio, Jaebok Choi

2020-Current year OA Pubs

Allogeneic hematopoietic cell transplantation (allo-HCT) is a highly effective, well-established treatment for patients with various hematologic malignancies and non-malignant diseases. The therapeutic benefits of allo-HCT are mediated by alloreactive T cells in donor grafts. However, there is a significant risk of graft-versus-host disease (GvHD), in which the donor T cells recognize recipient cells as foreign and attack healthy organs in addition to malignancies. We previously demonstrated that targeting JAK1/JAK2, mediators of interferon-gamma receptor (IFNGR) and IL-6 receptor signaling, in donor T cells using baricitinib and ruxolitinib results in a significant reduction in GvHD after allo-HCT. Furthermore, we showed that balanced …

Recruitment Strategies In The Integration Of Mobile Health Into Sickle Cell Disease Care To Increase Hydroxyurea Utilization Study (Mesh): Multicenter Survey Study, Chinonyelum Nwosu, Hamda Khan, Rita Masese, Judith M Nocek, Siera Gollan, Taniya Varughese, Sarah Bourne, Cindy Clesca, Sara R Jacobs, Ana Baumann, Lisa M Klesges, Nirmish Shah, Jane S Hankins, Matthew P Smeltzer

2020-Current year OA Pubs

BACKGROUND: Hydroxyurea is an evidence-based disease-modifying therapy for sickle cell disease (SCD) but is underutilized. The Integration of Mobile Health into Sickle Cell Disease Care to Increase Hydroxyurea Utilization (meSH) multicenter study leveraged mHealth to deliver targeted interventions to patients and providers. SCD studies often underenroll; and recruitment strategies in the SCD population are not widely studied. Unanticipated events can negatively impact enrollment, making it important to study strategies that ensure adequate study accrual.

OBJECTIVE: The goal of this study was to evaluate enrollment barriers and the impact of modified recruitment strategies among patients and providers in the meSH study …

Natural Products In Food And Agriculture, Stephen O. Duke

Oxford ICSB

Before the National Center for Natural Products Research (NCNPR) existed, I was Director of a USDA weed management lab. Two of my interests were natural products as herbicides and the chemical ecology of weed/crop interactions (allelopathy). Dr. James McChesney and I had several conversations about his vision for the NCNPR on the University of Mississippi campus. I was very interested in becoming a part of this, as his plan was to have a USDA lab that would study natural products for use in food and agriculture as part of the center. The USDA Agricultural Research Service established the Natural Product …

Preventing Ingredient Adulteration To Maintain Botanical Integrity, Katie Banaszewski

Oxford ICSB

The growing popularity of botanical products combined with the challenges of the supply chain to meet the ingredient demand has created opportunities for dishonest companies to take advantage of their clients for financial gain. Suppliers and manufacturers must comply with cGMPs (current Good Manufacturing Practices), specifically when it comes to the basic requirements of properly identifying crude botanicals in whole, cut, or powdered form, as well as botanical extracts and essential oils. Despite this regulatory requirement, a large portion of botanical ingredients and products sold in the marketplace are adulterated. Popular ingredients in high demand are intentionally substituted, diluted, or …

African & Caribbean Herbal Pharmacopieae - Curating Data For Product Development, David Katerere

Oxford ICSB

This presentation aims to provide a comprehensive examination of the Africa Herbal Pharmacopoeia (AHP) and the Caribbean Herbal Pharmacopoeia (CHP), highlighting their respective similarities and differences in the realm of traditional herbal medicine and product development. Both pharmacopoeias are important initiatives in curating indigenous knowledge related to medicinal plants. They are valuable resources for researchers, healthcare practitioners, and industry. This presentation will outline the methodological and logistical approaches employed in putting together monographs and the challenges faced. Furthermore, the comparative analysis will explore the regional nuances that shape the content of each pharmacopoeia, considering factors such as local traditions, ecological …

Adulteration - Why Does It Still Proliferate?, John Travis

Oxford ICSB

No abstract provided.

Chemistry, Biology, And Safety Of Volatile Organics From Aromatic And Medicinal Plants, Nicole Stevens

Oxford ICSB

Introduction Sleep is an important foundation of health, yet the U.S. Centers for Disease Control (CDC) notes that about 30% of adults to not get the recommended minimum of 7 hours’ sleep per night. Prescription treatments may help, but they carry risks such as side-effects, dependency, and medication interaction. Natural botanical extracts are a therapeutic possibility for improving sleep quality, but additional research is needed on their efficacy and safety. A system of natural products based on lavender was developed and tested in a human clinical study to evaluate effect on sleep, blood and safety markers, and gene expression modulation …

Assessment Of Condylar Morphology In Various Facial Types-Cbct Study, Dr.Shruti Patil

Annual Research Symposium

Mandibular condyle being part of the TMJ complex, its volume and shape play a pivotal role in treatment stability and outcomes in orthodontic and orthognathic patients over long term periods. Different loading patterns would result in different morphology of the TMJ. The association with different facial types and understanding the relationship between condylar position, morphology and jaw base divergence is limited. This study’s objective is to assess the condylar structure which includes condylar height, width and height of the fossa in different jaw base divergences.

A cross-sectional study was conducted in which 90 patients undergoing Orthodontic treatment were selected and …

A Survey Of Melatonin In Dietary Supplement Products Sold In The U.S., Rahul Pawar

Oxford ICSB

In the United States, melatonin products are widely available to consumers as dietary supplements. During the past few decades, melatonin products have gained increased popularity primarily as a sleep aid, with a variety of product forms available for different age groups of consumers. Recent reports have highlighted a rise in melatonin ingestion among children reported to poison control centers across the U.S. The increased use of melatonin-containing dietary supplements and reported deviation from labeled quantities has emphasized the need for additional research to better understand products in the marketplace.
The objective of this work was to measure the melatonin content …

Art, Family, And A Calling To Occupational Therapy, Erin Barrus

The Open Journal of Occupational Therapy

Karen Sames was born and raised in Milwaukee, WI. From an early age, she was surrounded by art. An experience with occupational therapy during the third grade jumpstarted her journey connecting art to occupation. Karen believes that art is a necessary part of life and credits much of her own personal success with art to her friends and family for their inspiration and to the instructors at the Eagan Art House in Minnesota. Her piece “Cherry Blossoms,” a pastel on paper, is based on a photograph taken by her son, who is currently living in Japan, and graces the cover …

Sibling Involvement: Highlighting The Influential Role Of Siblings In Supporting Children With Autism Spectrum Disorder, Gracie Krueger, Robyn Otty

The Open Journal of Occupational Therapy

Social impairments experienced by children diagnosed with autism spectrum disorder (ASD) can limit participation in meaningful occupations. Incorporating typically developing siblings of children with ASD in occupational therapy-based community settings is an emerging practice approach that aims to support children with ASD during social challenges to enhance their participation in daily activities. The inclusion of siblings in occupational therapy practice presents a unique opportunity to address social skill development while facilitating positive sibling relationships. In this Opinions in the Profession paper, the influential role siblings play as social models for their siblings with ASD will be examined. The purpose of …

Promoting Equity And Inclusion For Mothers Of Young Children In Academia, Sabina Khan

The Open Journal of Occupational Therapy

Equity and inclusion are critical factors in ensuring that mothers of young children are able to participate fully in occupational therapy academia. Mothers of young children often face significant barriers that prevent them from fully engaging in academic pursuits, including lack of access to childcare, limited support structures, and societal expectations regarding gender roles and caregiving responsibilities. This opinion paper reviews strategies for academics at various levels within academia to promote equity and inclusion for these individuals.

The Role Of Occupational Therapy In The Recognition, Assessment, And Treatment Of Presbyvestibulopathy, Jennifer Hill, Ellen Hudgins, Sharon Leonard

The Open Journal of Occupational Therapy

Sensory functions decline with age, and the likelihood of having multiple sensory impairments increases with age, potentially leading to decreased physical activity and performance, decreased social participation, poorer quality of life, and greater health care spending. Presbyvestibulopathy (PVP), a diagnosis established in 2019, is a vestibular dysfunction or loss related to the aging process characterized by mild bilateral vestibular deficits, chronic dizziness, unsteadiness, gait disturbance, and/or recurrent falls. Given the potential impact of vestibular dysfunction on occupational performance and participation in meaningful activities, occupational therapy’s (OT) role in PVP is evident; however, limited literature exists specific to OT and vestibular …

Improving Occupational Therapy Doctoral Students’ Social Awareness For Making Equitable Policy Decisions: A Quantitative Quasi-Experimental Study, Alysson Goodwin, Denise Crowley

The Open Journal of Occupational Therapy

Occupational therapy has set a strategic vision to increase equity and health access through leadership in all practice areas. To this end, educators in occupational therapy doctorate programs must increase the students’ ability to lead with an awareness of the social impacts of policy decisions. The purpose of this study was to explore educational opportunities to support occupational therapy doctorate students in developing social awareness for decision-making. The study aimed to use an e-learning module to increase social awareness surrounding a departmental decision about a white coat ceremony. A quantitative quasi-experimental one group pre-test post-test study examined if a significant …

Associations Between Learning Environment And Study Satisfaction Across Time: Two Cross-Sectional Analyses Of Occupational Therapy Students, Gry Mørk, Susanne G. Johnson, Astrid Gramstad, Linda Stigen, Tove Carstensen, Tore Bonsaksen

The Open Journal of Occupational Therapy

There is increasing attention toward students’ satisfaction and how they perceive the quality of the program they attend. This study examined stability and change across time with regard to the relationships between learning environment factors and occupational therapy students’ satisfaction with the program. In the two consecutive cross-sectional analyses performed in this study, 163 second-year students and 193 third-year students from all six occupational therapy education programs in Norway participated. The Course Experience Questionnaire was used to assess learning environment factors and study satisfaction. The data were analyzed with Pearson’s correlation coefficient r and with hierarchical linear regression. Bivariate associations …

The Relationship Between Holistic Admissions Criteria And Program Ranking Among Occupational Therapy Entry-Level Programs, Kristian Taylor, Cat-Tien Nguyen, Jenny Grant, Mary B. Brewster, Mary A. Barrett, Teal Benevides, Sharon M. Cosper

The Open Journal of Occupational Therapy

Holistic admissions criteria are one strategy to be more inclusive of students with a variety of experiences, cultures, and beliefs. The purpose of this study is to evaluate the relationship between holistic admissions criteria and occupational therapy program ranking. We used a retrospective cross-sectional cohort descriptive study design of occupational therapy programs in the United States to understand whether top performing programs employ holistic admissions criteria. Secondary descriptive analysis from the top and bottom 50 ranked occupational therapy programs in 2020 U.S. News & World Report (Morse et al., 2020) was completed. We used a nominal scale to classify programs …

Barriers That Affect Equity In The Occupational Therapy Admissions Process: Student And Faculty Perspectives, Quinn P. Tyminski, Lenin Grajo

The Open Journal of Occupational Therapy

The use of holistic admissions in higher education has been demonstrated to increase the diversity of incoming student classes; yet, in occupational therapy (OT) research, admissions processes remain under-explored. This phenomenological study aimed to explore the process of OT admissions from the perspective of students, faculty, and staff at a single OT program with the goal to create a more inclusive, equitable, and holistic process. Focus groups were conducted with first-year students, and an online survey was sent to faculty to explore perspectives on the admissions process, necessary qualities for an OT graduate student, and suggestions for increasing inclusion and …

Perspectives Of Occupational Therapy Graduates On Sentinel Events During Transitions To Practice: A Phenomenographic Study, Nileththi Achini De Silva, Eleanor Furtado, Anne W. Hunt

The Open Journal of Occupational Therapy

Research suggests new occupational therapists face many positive and negative experiences during their transition from student to therapist. Current research lacks information regarding sentinel events that occur during this shift. An exploration of sentinel events as interpreted through the life course perspective may inform how to support the transition to occupational therapist. The purpose of this study is to (a) determine sentinel events that occur during the transition to practice for new occupational therapists and (b) the impact of these events. A phenomenographic approach guided a semi-structured interview with 14 recent occupational therapy graduates. Interviews were transcribed verbatim and thematic …

The Effects Of Cervical Cancer Diagnosis On Occupational Performance, Wynnet Sinclair, Christine Mcconnell, Emily Clark, Katie B. Mcentire, Caitlin Lewis, Lyndsi Pound, Katherine Wuertz

The Open Journal of Occupational Therapy

Background: In the United States, it was predicted that approximately 13,960 new cases of invasive cervical cancer would be diagnosed in 2023 (American Cancer Society, 2023). The research question focused on identifying changes in occupational performance for patients with cervical cancer. The areas of occupational performance considered were activities of daily living, leisure, work, education, social participation, and mental health.

Methods: The respondents completed a cross-sectional, mixed methods Qualtrics survey. Likert scale questions captured the degree of functional impact of cervical cancer on the predetermined areas of occupational performance.

Results: Twenty-seven subjects (ages 18 to 70) fully …

Adolescent Perceptions Of Weighted Blankets And Quality Of Sleep: A Mixed Method Design, Tara D. S. Summers

The Open Journal of Occupational Therapy

Background: The purpose of this mixed methods case study was to describe the perceived sleep quality experience of an adolescent, without a pre-identified sleep need, when they used a weighted blanket during sleep.

Method: Adolescents (n = 5) 11 to 16 years of age completed a sleep diary for 7 days, sleeping with a self-selected weighted blanket for at least 3 days. A semi-structured individual interview was held after Day 7.

Results: The majority of the participants would like to continue using a weighted blanket for sleep. Eighty percent of the adolescents choose to sleep with a …

Occupational Therapists' Perceptions On Addressing Spirituality: A Cross Sectional Survey, Shannon Metzger, Jeanine Beasley, Jordan Marheineke, Amy Stites, Amy Riley, Christine Byam, Diane Maodush-Pitzer, Dawn R. Devries

The Open Journal of Occupational Therapy

Background: Occupational Therapy (OT) was founded as a holistic profession that addresses the mind, body, and spirit. Research indicates that occupational therapists feel uncomfortable incorporating spirituality into practice. Method: This study aimed to identify perceptions of occupational therapists in addressing the spiritual needs of their clients. A cross-sectional Qualtrics survey was adapted from the Religious/Spiritually Integrated Practice Assessment Scale (RSIPAS). The survey was electronically sent out by several professional OT organizations. It was sent to occupational therapists and OT assistants to obtain their perspective of incorporating spirituality in practice. Quantitative and qualitative data analysis was completed. Results: Of the 52 …

A ‘Friendly Visitor’ Volunteer Intervention For Hoarding Disorder: Participants’ Perceptions, Susan Noyes, Sarah Van Houten, Elizabeth Wilkins

The Open Journal of Occupational Therapy

Background: Determining and delivering effective interventions for Hoarding Disorder remains challenging, and appropriate resources are often unavailable. To address the need, the Friendly Visitor Program was designed in Portland, Maine, to pair people living with hoarding disorder with a trained volunteer to help with decluttering the living environment. The majority of the trained volunteers were occupational therapy students.

Method: This qualitative research study explored participants’ perceptions in a volunteer program that addresses hoarding behaviors. The study was conducted through an interpretivist, constructivist lens, examining the Friendly Visitor hoarding intervention program through individual, in-depth, semi-structured interviews with nine participants, …

Factors Influencing Driving Confidence In Older Adults, Jill Linder, Beth Ann Walker, Elizabeth Moore, Anne Hegberg

The Open Journal of Occupational Therapy

Background: It has been determined that both confidence and cognition impact driving performance and self-regulation. While it is known that cognitive decline impacts driving safety and that decreases in driving confidence can lead to self-driving regulation, further research is needed to determine whether cognition, demographics, and driving routines are associated with driving confidence.

Method: A non-experimental, cross-sectional design study using a convenience sample of 100 older adults was conducted to determine if individual factors are related to daytime and nighttime driving confidence.

Results: Multiple regression indicated that four variables predicted daytime driving confidence, including cognition, driving at …

Informing Modifications To Social Participation And Navigation (Span) For Adolescents With Social Anxiety Incorporating Pet Dogs, Nicole Porter, Gary Bedell, Jason Getzler, Megan Mueller

The Open Journal of Occupational Therapy

Background: Social anxiety is one of the most prevalent mental health challenges of adolescence and profoundly impacts social participation. This study obtained adolescent and parent feedback to inform a future modification of Social Navigation and Participation (SPAN) for use with adolescents with social anxiety incorporating pet dogs.

Methods: The study had two phases: Phase 1 included interviews with adolescents with social anxiety (n = 8) about their social participation experiences, strategies, pet dogs, and thoughts on a proposed intervention to promote social participation; and Phase 2 included on-line survey completed by the adolescents and their parents (n = 14) assessing …