Medicine and Health Sciences Commons^™

Quality Evaluation Tool For Clinician Online Continuing Medical Education, Brittany Rosen, Gary Kreps, James M. Bishop Mr., Skye L. Mcdonald

Health Behavior Research

The purpose of this study was to develop and assess an instrument evaluating the quality of online continuing medical education interventions for clinicians. A review of seminal literature for evaluating health-related websites was conducted to incorporate best practices from health education, health communication, and web-based design principles. After reviewing the literature, 12 preliminary quality indicators were developed. Two independent coders used the preliminary quality indicators to code continuing medical education interventions. Internal reliability of the preliminary indicators was calculated using the Krippendorff’s alpha coefficient. After completing the reliability testing and revising the tool, the quality evaluation framework consisted of six …

Exposure To Violence And Sleep Inadequacies Among Men And Women Living In A Shelter Setting, Pooja Agrawal, Julie Neisler, Michael S. Businelle Phd, Darla E. Kendzor Phd, Daphne C. Hernandez, Chisom Odoh, Lorraine R. Reitzel

Health Behavior Research

Exposure to violence may explain sleep inadequacies reported by homeless adults, with women being potentially more susceptible to violence and sleep disturbances than men. This study examined the association between violence and sleep inadequacies among homeless adults and explored differences by sex. Adult participants were recruited from a shelter (n = 194; 71.1% men, M_age = 43.8+12.2). Participants self-reported victimization and/or witnessing violence (mugging, fight, and/or sexual assault) at the shelter, sleep duration (over an average 24 hours), insufficient sleep (days without sufficient rest/sleep), and unintentional daytime sleep (days with unintentional sleep) in the past month. Linear regressions …

Diet Quality As A Mediator Of The Relation Between Income-To-Poverty Ratio And Overweight/Obesity Among Adults: Moderating Effect Of Sex, Sajeevika S. Daundasekara, Nipa P. Kamdar, Ashley Dao, Anna Greer, E. Lisako J. Mckyer, Daphne C. Hernandez

Health Behavior Research

Poverty status influences obesity and dietary quality, and dietary quality influences obesity. How these relationships differ by sex is unclear. The current study aims were to 1) determine whether dietary quality mediates the relation between income-to-poverty ratio (IPR) and overweight/obesity (OV/OB) among men and women, separately, and 2) determine whether either of the mediated paths differs by sex. Four cycles of NHANES (2007-2014) were merged to obtain an unweighted study sample of 12,768 adults with complete data. Exposure variables included self-reported measures of IPR, Healthy Eating index (HEI) total score to measure diet quality, and sex. Direct assessment of …

Adult Food Insecurity Is Associated With Heavier Weight Preferences Among Black Women, Layton Reesor-Oyer, Nadia Garcia Marroquin, Daphne C. Hernandez

Health Behavior Research

Food insecurity is related to overweight/obesity among women. However, it is unknown whether food insecurity impacts individuals’ desired body composition, and whether this relationship differs by race/ethnicity similar to perceived ideal weight status. This study aims to evaluate whether food insecurity is related to elevated preferred weight status (e.g., overweight/obese versus normal weight) among black, white, and Hispanic women classified as overweight/obese. Four waves of NHANES data (2007–2014) were merged and yielded a total of 907 black, 1,271 white, and 1,005 Hispanic non-pregnant adult (age 20 to 59) women classified as overweight/obese. Participants self-reported their preferred weight status, adult-level food …

Mammography Social Support For Women Living In A Midwestern City: Toward Screening Promotion Via Social Interactions, Wasantha P. Jayawardene, Mohammad R. Torabi, David K. Lohrmann, Ahmed H. Youssefagha

Health Behavior Research

Notwithstanding recommendations and interventions, the percentage of 50 – 74-year-old U.S. women who reported having had a mammography in the past two years remained below target coverage. Social interactions may influence mammography rates. To measure characteristics of social interactions in a Midwestern city as they relate to social support for mammography received by women older than 40 years of age. A cross-sectional study was conducted in Bloomington, Indiana, sending mail surveys to 3,000 telephone directory addresses selected by simple random sampling. An anonymous, self-administered, closed-ended, questionnaire with eight checklist items (for demographics) and six multipart semantic differential scale items (for …

Consistency Of Reported Barriers For Colorectal Cancer Screening Among Adults Who Have Never Been Screened, Cherie Conley, Amanda J. Dillard, Constance M. Johnson, John A. Updegraff, Wei Pan, Alyssa Langenberg, Isaac Lipkus

Health Behavior Research

Morbidity and mortality from colorectal cancer can be decreased by addressing patient barriers to colorectal cancer screening; especially among adults who have never been screened. Assessing changes in barriers over time may help practitioners better tailor interventions to address patient barriers. We assessed among adults ages 50 -75 who have never been screened for colorectal cancer (CRC) which barriers predict prospective screening. A sample of 560 adults who had never been screened, recruited from Growth for Knowledge’s online panel, completed a baseline and a six-month follow-up survey. Both surveys assessed screening barriers after an online intervention that involved conveying tailored …

Cross-Sectional Associations Of Opiate Misuse/Opioid Use Disorder Among Adults Experiencing Homelessness, Valentina Maza, Daphne C. Hernandez, Phd, Msed, Faahb, Darla E. Kendzor Phd, Michael S. Businelle Phd

Health Behavior Research

The purpose of this manuscript is to determine the prevalence of opioid misuse/opioid use disorder (OUD) among adults experiencing homelessness and describe characteristics that account for significant variance in relation to opioid misuse in those who misuse and do not misuse opioids. From six homeless shelters in Oklahoma City, adults participated in a survey about their demographics, substance use, mental health, and physical health from July to August of 2016 (n = 569). For assessing substance use, participants responded about their opioid misuse and diagnosis of OUD, current smoking status, arrests due to drug possession or driving while intoxicated, …

Health Literacy And Self-Rated Health Among Homeless Adults, Chisom Odoh Phd, Jennifer I. Vidrine Phd, Michael S. Businelle Phd, Darla E. Kendzor Phd, Pooja Agrawal, Lorraine R. Reitzel Phd

Health Behavior Research

Poor health literacy reduces the efficacy of behavior change interventions, hampers management of health conditions, and attenuates understanding of the prevention and treatment of diseases. Poor health literacy has also been linked to fair/poor self-rated health in domiciled samples; however, there is a paucity of studies on the relation amongst homeless adults, who bear a disproportionate burden of disease and disability and require a high level of care and access to health services. Here, we examined the association between health literacy and self-rated health among a convenience sample of homeless adults. Participants were recruited from six homeless-serving agencies in Oklahoma …

What Determines Young Adults’ Attitudes, Perceived Norms, And Perceived Behavioral Control Towards Healthy Sleep Behaviors? A Reasoned Action Approach, Paul Branscum, Katie Qualls Fay

Health Behavior Research

A common limitation to the design of public health sleep interventions is the overall lack of using theory. Previous researchers have utilized the theory of planned behavior and the reasoned action approach (RAA) to predict healthy sleep behaviors, however much of this research was done using reflective (or generalized) measures, which alone is likely inadequate to equip health practitioners with tangible information they can use to translate theory into practice. Therefore, the purpose of this study was to use formative (or belief-based) measures of the RAA to evaluate the determinants of attitudes, perceived norms, and perceived behavioral control (PBC) of …

Food Insecurity As A Predictor Of Hurricane Exposure Among Underserved Adolescents, Katherine R. Arlinghaus, Daphne C. Hernandez, Craig Johnston

Health Behavior Research

Low-income populations are at increased risk for experiencing negative hurricane exposures and food insecurity. However, little is known regarding how pre-hurricane food insecurity experiences are related to youth hurricane exposure. This study examined the types of hurricane disaster exposures low-income, ethnic minority adolescents experienced during Hurricane Harvey and examined the association between food insecurity and hurricane exposure. Low-income adolescents (n = 185) were recruited from a Houston-area school district. Two days before the hurricane, food insecurity was assessed. Adolescents with at least one affirmative answer on the 9-item USDA Child Food Security Survey Module were classified as food insecure. …

Negative School Experiences And Pain Reliever Misuse Among A National Adolescent Sample, Kelsi J. Wood, Keith A. King, Rebecca A. Vidourek, Ashley L. Merianos

Health Behavior Research

A recent public health concern is the nonmedical use of prescription drugs among U.S. adolescents. The purpose of this study was to determine the relationship between negative school experiences and lifetime and past year pain reliever misuse among adolescents enrolled in high school nationwide. A secondary analysis was performed using the National Survey on Drug Use and Health 2017 data. Participants included 8,337 adolescents enrolled in 9^th -12^th grades. A total of 6.0% of high school students reported they had misused pain relievers in their lifetime, and 3.9% reported they had misused pain relievers during the past year. …

Using The Theory Of Triadic Influence To Examine Correlates Of Positive Drug Expectancies Among Hispanic Adolescents, Wura Jacobs, Lauren Bartoszek, Jennifer Unger

Health Behavior Research

This study employs the Theory of Triadic Influence (TTI) which articulates the different variables that influence health-related behaviors into streams of influence—intrapersonal, social, and cultural—to better understand factors that influence positive drug use expectancies (PDE) among Hispanic adolescents. Data for the study came from Project RED, which included 1,963 high school students in Southern California. The relationships between participants’ drug expectancies and different streams of influence were examined using regression analysis. Participants were mostly females (54.2%); with a mean age of 17.13 years. Controlling for other covariates, there were no cultural stream variables associated with PDE (Model 1). Model 2, …

The Spread And Utility Of Social Network Analysis Across A Group Of Health Behavior Researchers, Megan S. Patterson, Tyler Prochnow Med, Patricia Goodson

Health Behavior Research

Social network analysis (SNA), both as theory and methodology, is a powerful framework for delimiting and studying health behaviors. Using SNA allows scholars to answer new research questions, innovatively investigate the social and systemic contexts of health and behavior, and collaborate on multi- or inter-disciplinary projects. As a result, SNA is growing in popularity within health behavior research and practice. Despite SNA’s contribution and appeal, few health behavior researchers and practitioners have access to formal SNA education; much of the current training efforts occur outside degree-granting curricula. Therefore, the aims of this paper were to: 1) assess the diffusion of …

Advancing Academic Careers Through Formal Professional Mentorship: The Research Scholars Mentorship Program (Rsmp), Matthew Lee Smith, Lorraine R. Reitzel, Jessica M. Rath, Lisa Benz Scott, David Wyatt Seal

Health Behavior Research

Mentorship is an essential component of professional development for young and emerging scholars. In partnership with the Kellogg Health Scholars Program, the American Academy of Health Behavior (AAHB) developed the 12-month Research Scholars Mentorship Program (RSMP) as a mechanism to facilitate high-quality mentorship interactions among junior and seasoned investigators within the Academy. This article provides a rationale, history, and description of the RSMP, as well as the collective scholarly achievements of the Cohorts and future directions. To date, 44 Pairs have initiated or completed the program. Products written and submitted by the Pairs during the 12-month mentorship period have included …

Mentoring The Next Generation Of Health Professionals: A Mentor-The-Mentor Approach, Andrea L. Demaria, Stephanie Meier, Jaziel L. Ramos-Ortiz

Health Behavior Research

The purpose of this commentary is to share team-based mentoring strategies used for successful interdisciplinary research team productivity and sustainability. This commentary lists and describes the top ten considerations for building a productive mentor-the-mentor approach, inspired by the train-the-trainer method. The approach promotes reciprocal training and individualized experiences, while producing positive professional and personal outcomes. We pinpoint how relationship-building rooted in passion and clear communication, explicit expectations and regular celebrations, and routine paired with a bit of play enhances productivity and encourages future health professionals to emerge as leaders in the field.

Strategies For Successful Long-Distance Mentoring, Annie Nguyen, Scott Rhodes

Health Behavior Research

Mentorship offers benefits to both the mentee and mentor in terms of professional development and productivity. It can take many forms and is not limited to mentee-mentor pairs that are employed at the same institution. Mentoring relationships that span institutions offer an avenue for expanding one’s professional network beyond the local environment. We refer to this type of mentorship as “long-distance mentoring.” We offer four critical strategies and reflections for successful long-distance mentoring based on our experience in the AAHB Research Scholars Mentorship Program.

Perivascular Waste Metabolites Clearance In Central Nervous System (Cns), Yiming Cheng

Dissertations

Efficient clearance of interstitial waste metabolites is essential for normal brain homeostasis. Such effective clearance is hampered by the lack of a lymphatic system in the brain, and the cerebrospinal fluid (CSF) is unable to clear large size waste metabolites in the brain. Here, a novel idea that brain arterial endothelium and smooth muscle cells reactivity regulates the clearance of these water-insoluble large size waste metabolites through the perivascular dynamic exchange, and that low dose ethanol promotes this perivascular clearance is proposed.

In Aim 1, the biodistribution of a large size waste metabolite (Amyloid-β protein mimic) in rat perivascular space …

Mitochondria Imaging And Targeted Cancer Treatment, Tinghan Zhao

Dissertations

Mitochondria are essential organelles as the site of respiration in eukaryotic cells and are involved in many crucial functions in cell life. Dysfunction of mitochondrial metabolism and irregular morphology have been frequently found in human cancers. The capability of imaging mitochondria as well as regulating their microenvironment is important both scientifically and clinically. Mitochondria penetrating peptides (MPPs), certain peptides that are composed of cationic and hydrophobic amino acids, are good candidates for mitochondria targeting. Herein, a novel MPP, D-argine-phenylalanine-D-argine-phenylalanine-D-argine-phenylalanine-NH₂ (rFrFrF), is conjugated with a rhodamine-based fluorescent chromophore (TAMRA). The TAMRA-rFrFrF probe exhibits advantageous properties for long-term mitochondria tracking of …

Connectivity Differences Between Gulf War Illness (Gwi) Phenotypes During A Test Of Attention, Tomas Clarke, Jessie Jamieson, Patrick Malone, Rakib U. Rayhan, Stuart Washington, John W. Vanmeter, James N. Baraniuk

Faculty Publications, Department of Mathematics

One quarter of veterans returning from the 1990–1991 Persian Gulf War have developed Gulf War Illness (GWI) with chronic pain, fatigue, cognitive and gastrointestinal dysfunction. Exertion leads to characteristic, delayed onset exacerbations that are not relieved by sleep. We have modeled exertional exhaustion by comparing magnetic resonance images from before and after submaximal exercise. One third of the 27 GWI participants had brain stem atrophy and developed postural tachycardia after exercise (START: Stress Test Activated Reversible Tachycardia). The remainder activated basal ganglia and anterior insulae during a cognitive task (STOPP: Stress Test Originated Phantom Perception). Here, the role of attention …

Research News. Grants, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Grants (2015-)

Grants and contracts awarded during October-December 2019

Research News. Publications, 2019. Volume 4, University Of Mississippi. School Of Pharmacy, Soumyajit Majumdar

Publications (2015-)

Publications that appeared during the period October 1 through December 31, 2019

Effectiveness Of Balloon Angioplasty And Stent Angioplasty: Wound Healing In Critically Limb Ischemic, Wisnu Pamungkas, Patrianef Darwis

The New Ropanasuri Journal of Surgery

Introduction. Critical limb ischemia (CLI) is a vascular disease that has a significant amputation and mortality risk with diabetes mellitus; the most significant risk factor in CLI is prevalent among Indonesian. Endovascular intervention (EVI) is preferred in treating CLI because it is non-invasive and effective. Balloon angioplasty and stent angioplasty are the most common method of EVI in Indonesia. This study aims to compare the effectiveness of balloon angioplasty and stent angioplasty on wound healing in CLI.

Method. A cross sectional study enrolled 90 subjects of CLI who underwent endovascular intervention using balloon angioplasty dan stent angioplasty from …

The Role Of Melatonin In Improving Hypoxia In Malignant Tumor: A Mini-Review, Diani Kartini, Akmal Taher, Sonar S. Panigoro, Rianto Setiabudy, Sri W. Jusman, Sofia M. Haryana, Murdani Abdullah, Primariadewi Rustamadji

The New Ropanasuri Journal of Surgery

No abstract provided.

Psychoeducation “Aku Peduli” For Parent With Typically Developing Children At An Inclusive Kindergarten, Andi Nur Zamzam Arman, Farida Kurniawati

ASEAN Journal of Community Engagement

This study examined the effectiveness of “AKU PEDULI” psychoeducation in helping the parents of typically developing children to increase their knowledge of special needs children and inclusive education at an inclusive kindergarten. “AKU PEDULI” is abbreviated from Anak Berkebutuhan Khusus dan Pendidikan Inklusif (Special Needs Children & Inclusive Education). Quantitative methods were used in both the pre-test and post-test parts of the research. Six mothers aged 28–34 years, of typically developing children were selected to participate in the study through accidental sampling. Participants were required to be parents of typically developing children who attend an inclusive kindergarten and who have …

Patient Safety Smartphone Application For Quality Assurance In Primary Healthcare Facilities, Levina Chandra Khoe, Ajeng Pramastuty, Boy Subirosa Sabarguna, Herquranto Herqutanto

ASEAN Journal of Community Engagement

In order to achieve high-quality healthcare, patient safety should be improved and monitored regularly. Moreover, accreditation on healthcare facilities is being requested in recent years. Mobile application can serve as a tool for community healthcare centre’s (Puskesmas) to assess their accreditation score, especially patient safety. To provide as a tool for self-monitoring for patient safety elements. This is a case-based article focuses on the development of smartphone application using the input-process-output-outcome scheme as the framework. We reviewed regulation of health minister on Puskesmas accreditation and developed a checklist and scoring for patient safety components. This is the first mobile application …

Cytotoxic Activity Of Stem Of Pycnarrhena Cauliflora Through Apoptosis Induction On Human Breast Cancer Cell Line T47d, Masriani, Rudiyansyah, Rini Muharini, Eny Enawaty

Pharmaceutical Sciences and Research

Cytotoxic activities of extracts of Pycnarrhena cauliflora leaves, stems and roots on some human cancer cells have been known. However, the cytotoxicity of stem of Pycnarrhena cauliflora on human breast cancer cell line T47D through an apoptosis induction has not been proven yet. This study was an effort in understanding the cytotoxic activity of stem of Pycnarrhena cauliflora through apoptosis induction. The crude ethanol extract was partitioned between n-hexane and dichloromethane at pH 3, 7 and 9, which was subsequently tested for their cytotoxic activity against human breast cancer cell line T47D by using 3-(4,5-dimethylthiazol-2-yl)- 2,5-diphenyltetrazolium bromide (MTT). Flow cytometric …

Model Hewan Coba Pada Penelitian Diabetes, Fauzul Husna, Franciscus D. Suyatna, Wawaimuli Arozal, Erni H. Purwaningsih

Pharmaceutical Sciences and Research

The animal model has been widely used and contributed vastly to the scientific research over the years. While it can be used as an alternate subject in a study, the selection of the animal is crucial to assess and investigate the influence of the environment and genes on the pathogenesis of a disease. Many factors contribute to the choosing of the animal. They can be ranged from the similarities with the modelled object, easily looked after with less expensive cost, good reproductive performance, ability to produce blood and tissue samples, well-known genetic composition, and the status of the disease can …

Chemical Components Of Ocimum Basilicum L. And Ocimum Tenuiflorum L. Stem Essential Oils And Evaluation Of Their Antioxidant Activities Using Dpph Method, Ni Putu Ermi Hikmawanti, Hariyanti, Nurkamalia, Sahera Nurhidayah

Pharmaceutical Sciences and Research

Ocimum basilicum L. and Ocimum tenuiflorum L. are two types of plants from Ocimum (Lamiaceae). One of their chemical compounds is essential oil. Essential oil might have an antioxidant activities. The part of the plants which are often wasted and never used are stem. This study aimed to analyze the chemical components of O. basilicum L. and O. tenuiflorum L. stem essential oils and evaluate their antioxidant activities. Essential oils were obtained by steam-water distillation. Analysis of chemical component of essential oil was performed using Gas Chromatography-Mass Spectroscopy (GC-MS). Antioxidant activities were evaluated with DPPH method and then the IC50 …

Identification And Evaluation Of Antibacterial Compounds From The Vibrio Sp. Associated With The Ascidian Pycnoclavella Diminuta, Abdurraafi’ Maududi Dermawan, Elin Julianti, Masteria Yunovilsa Putra

Pharmaceutical Sciences and Research

This study aims to obtain secondary metabolites that have antibacterial activity from bacteria endophytic of ascidian Pycnoclavella diminuta collected from the coast of Bitung, North Sulawesi, Indonesia. The research was started with screening antibacterial activity of six bacteria isolated from P. diminuta. The active bacteria were selected for identification using standard biological molecular method and further fermentation to produce secondary metabolites. The isolation of secondary metabolites was conducted by various chromatography method and then selected fraction was based on the antibacterial activity from bioautography results. The result showed that the active isolate by coding M2.Tnk.Bt 5.10-3.2 was identified as Vibrio …

Incidence Of Initial Renal Replacement Therapy Over The Course Of Kidney Disease In Children., Derek K. Ng, Matthew B. Matheson, Bradley A. Warady, Susan R. Mendley, Susan L. Furth, Alvaro Muñoz

Manuscripts, Articles, Book Chapters and Other Papers

The Chronic Kidney Disease in Children Study, a prospective cohort study with data collected from 2003 to 2018, provided the first opportunity to characterize the incidence of renal replacement therapy (RRT) initiation over the life course of pediatric kidney diseases. In the current analysis, parametric generalized gamma models were fitted and extrapolated for RRT overall and by specific treatment modality (dialysis or preemptive kidney transplant). Children were stratified by type of diagnosis: nonglomerular (mostly congenital; n = 650), glomerular-hemolytic uremic syndrome (HUS; n = 49), or glomerular-non-HUS (heterogeneous childhood onset; n = 216). Estimated durations of time to RRT after …