Medicine and Health Sciences Commons^™

Perivascular Waste Metabolites Clearance In Central Nervous System (Cns), Yiming Cheng

Dissertations

Efficient clearance of interstitial waste metabolites is essential for normal brain homeostasis. Such effective clearance is hampered by the lack of a lymphatic system in the brain, and the cerebrospinal fluid (CSF) is unable to clear large size waste metabolites in the brain. Here, a novel idea that brain arterial endothelium and smooth muscle cells reactivity regulates the clearance of these water-insoluble large size waste metabolites through the perivascular dynamic exchange, and that low dose ethanol promotes this perivascular clearance is proposed.

In Aim 1, the biodistribution of a large size waste metabolite (Amyloid-β protein mimic) in rat perivascular space …

Mitochondria Imaging And Targeted Cancer Treatment, Tinghan Zhao

Dissertations

Mitochondria are essential organelles as the site of respiration in eukaryotic cells and are involved in many crucial functions in cell life. Dysfunction of mitochondrial metabolism and irregular morphology have been frequently found in human cancers. The capability of imaging mitochondria as well as regulating their microenvironment is important both scientifically and clinically. Mitochondria penetrating peptides (MPPs), certain peptides that are composed of cationic and hydrophobic amino acids, are good candidates for mitochondria targeting. Herein, a novel MPP, D-argine-phenylalanine-D-argine-phenylalanine-D-argine-phenylalanine-NH₂ (rFrFrF), is conjugated with a rhodamine-based fluorescent chromophore (TAMRA). The TAMRA-rFrFrF probe exhibits advantageous properties for long-term mitochondria tracking of …

Effectiveness Of Balloon Angioplasty And Stent Angioplasty: Wound Healing In Critically Limb Ischemic, Wisnu Pamungkas, Patrianef Darwis

The New Ropanasuri Journal of Surgery

Introduction. Critical limb ischemia (CLI) is a vascular disease that has a significant amputation and mortality risk with diabetes mellitus; the most significant risk factor in CLI is prevalent among Indonesian. Endovascular intervention (EVI) is preferred in treating CLI because it is non-invasive and effective. Balloon angioplasty and stent angioplasty are the most common method of EVI in Indonesia. This study aims to compare the effectiveness of balloon angioplasty and stent angioplasty on wound healing in CLI.

Method. A cross sectional study enrolled 90 subjects of CLI who underwent endovascular intervention using balloon angioplasty dan stent angioplasty from …

Association Between The Adequacy Of Preoperative Antituberculosis Treatment With Abdominal Postoperative Morbidity And Mortality On Tuberculosis Patients, Riza El Anshori, Agi S. Putranto

The New Ropanasuri Journal of Surgery

Introduction. The adequacy of tuberculosis treatment before abdominal surgery is a dilemma faced by surgeons who aims for low risk of morbidity and mortality. In addition, there is no data on morbidity and mortality post abdominal operation on TB patients in RSCM and RS Persahabatan. Therefore, this research aims to show the correlation between the adequacy of preoperative TB treatment and postoperative morbidity (fistula enterocutaneous, obstruction, and surgical site infection) and mortality.

Method. This study is a descriptive-analytic cross-sectional study done in Cipto Mangunkusumo Hospital dan Persahabatan Hospital using total sampling method, a total of 59 subjects with …

The Role Of Melatonin In Improving Hypoxia In Malignant Tumor: A Mini-Review, Diani Kartini, Akmal Taher, Sonar S. Panigoro, Rianto Setiabudy, Sri W. Jusman, Sofia M. Haryana, Murdani Abdullah, Primariadewi Rustamadji

The New Ropanasuri Journal of Surgery

No abstract provided.

Pengaruh Pemberian Jus Mentimun Dan Minuman Isotonik Terhadap Tingkat Dehidrasi Pada Latihan Zumba Fitness, Rizki Yudha Pratama, Imas Damayanti, Yati Ruhayati

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian jus mentimun dan minuman isotonik terhadap tingkat dehidrasi. Metode yang digunakan yaitu dengan eksperimen dengan desain penelitian cross over design. 8 orang mahasiswa keperawatan UPI 2018 berpartisipasi sebagai sampel dalam penelitian ini. Dehydrating exercise test yang digunakan dalam penelitian ini adalah Zumba fitness selama 60 menit. Instrumen pengambilan data menggunakan Urine Refractometer Spesific Gravity dan 5 visual analog scale. Hasil dari penelitian ini menunjukkan bahwa tidak terdapat perbedaan yang signifikan antara hasil pre-test dan post-test pada jus mentimun dan minuman isotonik terhadap tingkat dehidrasi sebesar p(0.83) dan p(1.52). Pada penilaian subjektif tidak terdapat …

Hubungan Komposisi Tubuh Dengan Kesegaran Jasmani Pada Atlet Hockey, Nandita Nury Latifah, Ani Margawati, Ayu Rahadiyanti

Jurnal Keolahragaan

Komposisi tubuh yang tidak optimal dapat menurunkan kesegaran jasmani atlet sehingga dapat terjadi penurunan performa ketika bertanding. Tujuan dari penelitian ini adalah mengetahui hubungan persen lemak tubuh, persen massa otot, dan somatotype dengan kesegaran jasmani pada atlet hockey. Desain penelitian yaitu cross-sectional dengan jumlah subjek 35 atlet di Pelatihan Hockey Universitas Negeri Semarang dan Universitas Negeri Yogyakarta yang dipilih dengan purposive sampling. Data persen lemak tubuh dan persen massa otot diukur menggunakan bioelectrical impedence analysis (BIA). Data somatotype menggunakan metode antropometri Heath-Carter dan data kesegaran jasmani berupa nilai VO2max diambil menggunakan metode Balke. Analisis data menggunakan uji Pearson, …

Efektivitas Small-Sided Games Dan Interval Training Terhadap Peningkatan Daya Tahan Aerobik Pada Pemain Sepakbola U-17, Andi Tri Arianto, Caly Setyawan

Jurnal Keolahragaan

Penelitian ini bertujuan untuk membandingkan pengaruh antara latihan small sided games (SSG) dan interval training (IT) terhadap daya tahan aerobik pemain sepakbola under-17. Sebanyak 24 pemain sepakbola U-17 yang dibagi menjadi 2 grup: grup SSG (n = 12) dan grup IT (n = 12) mengikuti program latihan selama 6 minggu. Instrumen penelitian yang digunakan adalah Yo-Yo Intermitten Recovery Test. ANAVA dua jalur digunakan untuk proses analisis data. Pemain dari kedua grup menunjukkan peningkatan yang sama pada daya tahan aerobik selama periodesasi latihan 6 minggu. Hasil ini menunjukkan bahwa SSG dan IT sama efektif dalam meningkatkan daya tahan aerobik …

Efektivitas Massage Frirage Dan Kombinasi Back Massage-Stretching Untuk Penyembuhan Nyeri Pinggang, Ardi Utomo, B.M. Wara Kushartanti

Jurnal Keolahragaan

Penelitian ini bertujuan untuk mengungkapkan: (1) pengaruh jenis perlakuan massage frirage dan kombinasi back massage-stretching untuk penyembuhan nyeri pinggang, (2) pengaruh kondisi cedera akut dan kronis terhadap penyembuhan nyeri pinggang, dan (3) interaksi jenis perlakuan dengan kondisi cedera terhadap penyembuhan nyeri pinggang yang ditunjukkan peningkatan ROM pinggang pada pasien Physical Therapy Clinic Fakultas Ilmu Keolahragaan Universitas Negeri Yogyakarta (PTC FIK UNY). Penelitian ini adalah eksperimen dengan desain faktorial 2 x 2, dengan menggunakan tes awal dan tes akhir. Subjek penelitian ini adalah 40 orang pasien klinik PTC yang mengalami nyeri pinggang kronis maupun akut akibat aktivitas kerja yang berjenis kelamin …

Association Between Obesity And Hormone Receptor Characteristics Of Primary Breast Cancer At Cipto Mangunkusumo General Hospital, Jakarta, In 2017, Hardian Gunardi, Diani Kartini

The New Ropanasuri Journal of Surgery

Introduction. Obesity is an independent risk factor and prognostic factor of primary breast cancer. Abundant adipose tissue would lead to increment of blood estrogen level; thus, promoting proliferation of cancer cell, especially those with positive estrogen receptor (ER) and progesterone receptor (PR). No study reported the association between obesity and hormone receptor characteristics of primary breast cancer in Indonesia.

Method. We collected cases of primary breast cancer which is diagnosed and undergone immunohistochemistry examination at Cipto Mangunkusumo General Hospital in 2017. The subjects divided into obese group and non-obese group. The ER and PR characteristics of both groups were compared …

Correlation Between Internal Jugular Vein Tunnel Cuffed Catheter Tip Position As Hemodialysis Access With Suspected Catheter Related Bacteremia And Related Risk Factors At Rscm 2018–2019, Susatyo J. Pratomo, Akhmadu Muradi

The New Ropanasuri Journal of Surgery

Introduction. Infection is the main complication of prolonged–term catheter uses as hemodialysis access. The KDOQI recommends the insertion of tunnel venous hemodialysis catheter in the right internal jugular vein (IJV) where the tip placed in the right atrium and the arterial opening enfacing the mediastinum. The previous study showed that the incidence of catheter–related bacteremia (CRB) is 35% at three months' use and 54% at six months' use. The TCC tip position as hemodialysis access in left IJV is correlated more to dysfunction and infection compared to the right IJV.

Method. A cross–sectional study was conducted with 62 subjects …

Initial Experience On Laparoscopic Pyeloplasty In Persahabatan General Hospital, Jakarta: A Case Series, Moammar Ar Siregar, Hendy Mirza

The New Ropanasuri Journal of Surgery

Introduction. Untreated ureteropelvic junction obstruction would lead to infection and many other complications. The gold standard to treat this condition is pyeloplasty. Nowadays, laparoscopic pyeloplasty has emerged as a potential modality better than open pyeloplasty.

Method. Data retrospectively obtained from the medical records of UPJO patients at Persahabatan Hospital, Jakarta. The patient’s age, gender, weight, and BMI noted. Duration of operation, intraoperative blood loss, and complications recorded as the intraoperative status. Length of hospital stay, pain score on the first post-operative day, time to do the daily activity, and return to work recorded as post-operative variables of this …

Bedside Thyroid Palpation Technique As Indicator For Penetration/Aspiration Risk In Stroke Patients, Yung-Chun Chi, Mu-Hung Tsai, Jerry Tsung-Kai Lin, Yi-Chen Yu, Shih-Chung Chang

Rehabilitation Practice and Science

Background: Bedside thyroid cartilage palpation technique is a quick and non-invasive swallowing screening test. However, the correlation between thyroid cartilage movement and penetration/aspiration risks in stroke patients has not been conclusive to date. Therefore, we compared the result of videofluoroscopic swallowing study (VFSS) and bedside thyroid cartilage palpation to determine the penetration/ aspiration risks in stroke patients. Material and methods: Our study included 53 patients admitted to a medical center for rehabilitation within 6-months of stroke onset. We recorded penetration-aspiration scale by VFSS and compared it with a bedside thyroid cartilage palpation technique. Results: Our results show significant higher rates …

Voice Disorders In Teachers, Hsin-Yu Chien, Feng-Chuan Lin, Yu-Lin Huang

Rehabilitation Practice and Science

Teachers have higher occupational voice demands than the general populations. In addition to speaking intensively in a noisy environment for a long period of time, the lack of vocal hygiene education and vocal training experience will lead to high-risk for developing voice disorders. Although voice disorders are not life-threatening diseases, it affects teachers in many aspects. In addition to impacting teachers' personal physical and psychological condition, it also interferes with the quality of students' learning, which then bring down teachers' teaching and life quality, and even more so on teachers' mental health and career path. In order to help teachers …

Retrospective Study Of Neurogenic Bladder Complications In Patients With Chronic Spinal Cord Injury, Sheng-Min Chang, Sheng-Wei Zeng

Rehabilitation Practice and Science

Recent advances in medicine have greatly prolonged the average lifespan of patients with chronic spinal cord injury (SCI). However, many complications arise as the disease enters the chronic phase. SCI is known to cause limb weakness and paresthesia, it also causes multiple system abnormalities that cannot be easily ignored. Particularly troublesome issues develop due to the urinary system complications resulting from the neurogenic bladder. These include overactive bladder, detrusor external sphincter dyssynergia, vesicoureteral reflux, urolithiasis, urinary tract infection (UTI), and even chronic kidney disease. All these issues cause annoying problems that disturb the patient’s health and quality of life. The …

Analysis Of Ifn-Gamma And Il-10 Levels As Markers Of Inflammation And Response Therapy Of Anti-Tuberculosis In Mdr Lung Tb Patients, Herni Setyawati, Soedarsono Soedarsono, Yulistiani Yulistiani, Umi Fatmawati

Folia Medica Indonesiana

Multidrug-Resistant Tuberculosis (MDR TB) is caused by an organism that is resistant to at least isoniazid and rifampisin, the two most potent TB drug. Immune response to against Mycobacterum tuberculosis infection is related to the function of immunity. The function of interferon-γ (pro-inflammatory) is to activate macrophages, to stimulate antimicrobial molecules (to reactive oxygen species and nitric oxide), and to inhibits interleukin-10. Interleukin-10 function is to triggers humoral immunity, to inhibit IFN- γ. This study aimed to analyze level changes and the correlation with clinical data, also months of MDR TB patients who received standard OAT therapy. This was an …

Correlation Of Mothers With History Of Diabetes Mellitus And Infants With Anti-Gad65, Nanda Fadhilah Witris Salamy, Gadis Meinar Sari, Bambang Purwanto, Sulistiawati Sulistiawati

Folia Medica Indonesiana

The aim of this study was to analyze human sperm motility, viability, and morphology before and after cryopreservation. This true laboratory experimental study had pre and post randomized one group design. The study was conducted at the Embryology, Andrology, and Genetics Laboratory, Department of Medical Biology, Faculty of Medicine, Universitas Airlangga from August to November 2017. The eighteen samples of fresh semen were collected from male volunteers who agreed and signed the informed consent of the study. Samples were analyzed their motility, viability, and morphology before and after cryopreservation. Results of this study indicated differentiation between motility before and after …

Predictive Modeling Of Influenza In New England Using A Recurrent Deep Neural Network, Alfred Amendolara

Theses

Predicting seasonal variation in influenza epidemics is an ongoing challenge. To better predict seasonal influenza and provide early warning of pandemics, a novel approach to Influenza-Like-Illness (ILI) prediction was developed. This approach combined a deep neural network with ILI, climate, and population data. A predictive model was created using a deep neural network based on TensorFlow 2.0 Beta. The model used Long-Short Term Memory (LSTM) nodes. Data was collected from the Center for Disease Control, the National Center for Environmental Information (NCEI) and the United States Census Bureau. These parameters were temperature, precipitation, wind speed, population size, vaccination rate and …

Elastic Band Training Improves Adiposity And Physical Performance In Adults With Prader-Willi Syndrome: A Pilot Study, Valeria Chiu, Sheng-Hsun Chou, Hsin-Chi Wu, I-Shiang Tzeng, Che-Yi Chao, Pei-Jung Huang, Li-Ping Tsai

Rehabilitation Practice and Science

OBJECTIVE: The aim of this study was to investigate the changes in the regional fat distribution of body composition and the physical performance of adults with Prader-Willi syndrome (PWS) after progressive elastic band (EB) training. METHODS: Participants were trained three times per week, performing three sets of 15-20 repetitions for each of the exercises with EB for 24 weeks. Changes in body composition were measured using dual-energy X-ray absorptiometry. Physical performance was assessed by determination of hand grip strength, the timed up-and-go test, the 30-second chair stand test, the 2-minute step test, and the Berg Balance Scale. RESULTS: Six participants …

Cytomegalovirus Infection Complicated With Severe Rhabdomyolysis And Dysphagia: A Casereport And Literature Reviewarticle, Heng-An Yeh, Yu-Jen Chen, Jean-Lon Chen

Rehabilitation Practice and Science

Cytomegalovirus(CMV) is a common virus that usually occurs in immunocompromised patients. After primary infection with CMV, the virus becomes latent in multiple organs and can later be reactivated during severe immune system dysregulation. Rhabdomyolysis is a disease of human muscle cell necrosis, and the rapid dissolution of damaged or injured muscles may lead to acute kidney injury or multiple organ failure. After reviewarticleing relevant literature, patients with severe rhabdomyolysis caused by CMV infection are rarely reported and even less commonly, CMV leads to severe dysphagia. The patient was a 35-year-old woman without underlying disease. Two months before hospitalization,she visited the …

Association Between Obesity And History Of Atopy With Atopic Dermatitis In Children: A Cross-Sectional Study, Putu Nila Wardhani Batan, Ariana Ariana, Made Wardhana

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The prevalence of atopic dermatitis (AD) has rapidly increased in the past 4 decades and has been mostly observed in children. The prevalence of obesity has also significantly increased worldwide, suggesting that the two conditions may be associated.

Methods: This retrospective analytic study involved a cross-sectional design and used secondary data taken from the medical record of patients who visited the Pediatric Dermatology Subdivision at Dermatology and Venereology Polyclinic Sanglah General Hospital from January 2015 to December 2015. Thirty-two samples were selected.

Results: The prevalence ratio of obesity among subjects with AD was 2.178 (95% CI …

Prevalence And Risk Factors Of Bacterial Vaginosis Among Female Sex Workers In Surakarta, Rini Hastuti, Danu Yuliarto, Agung Triana, Willa Damayanti, Rakhma Tri Irfanti, Mardiana Mardiana, Putti Fatiharani Dewi, Ambar Aliwardani, Ervianti Abas, Sulistyo Sulistyo, Prasetyadi Mawardi, Endra Yustin Ellistasari

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Bacterial vaginosis (BV) is the most common vaginal infection in women of reproductive age and increases the risk of acquiring human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs). Data regarding the association between sexual activity and BV acquisition is contradictory. Thus, tracking the prevalence and associated risk factors of BV among female sex workers (FSWs) is necessary to improve our understanding and control of STDs and the HIV epidemic.

Methods: The subjects of this study were FSWs in Surakarta. This study adopted a cross-sectional design, and diagnosis was established using Amsel criteria. Interviews were conducted …

The Epidemiology Of Skin Cancer At Dr. Cipto Mangunkusumo National Central General Hospital From 2014 To 2017, Larisa Paramitha Wibawa, Melody Febriana Andardewi, Inge Adi Kristanti, Riesye Arisanty

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: The incidence of skin cancer has been increasing over the past decades globally. At present, there is no valid national cancer data in Indonesia. The purpose of this study is to evaluate the increment of skin cancer cases at Dr. Cipto Mangunkusumo National General Hospital, Jakarta.

Methods: In this retrospective descriptive study, we evaluated all pigmented skin tumor cases from June 2014 to June 2017. Data were obtained from the Department of Anatomical Pathology and medical records at Dr. Cipto Mangunkusumo National General Hospital. Data were compared with previous reports.

Results: From 263 skin cancer cases, …

Langerhans Cell Histiocytosis: Diagnosis And Management, Lusiana Lusiana, Hikari Ambara Sjakti, Githa Rahmayunita, Tjut Nurul Alam Jacoeb, Inge Ade Krisanti

Journal of General - Procedural Dermatology and Venereology Indonesia

Langerhans cell histiocytosis (LCH) is a rare disorder characterized by abnormal clonal proliferation of Langerhans dendritic cells. The incidence of LCH is 1 to 3 cases per 1 million children worldwide, and occurs most frequently in children of 1–4 years of age. The etiopathogenesis of LCH, whether it is neoplastic or reactive, is still controversial. Langerhans cell histiocytosis has a wide spectrum of clinical features, and dermatological abnormalities usually occur early. The most frequent lesions are elevated yellowish-red translucent papules about 1–2 mm in diameter and generally located in seborrheic areas. The most recent classification (the Histiocyte Society study 2017) …

The Use Of Systemic Medications In Pediatric Dermatoses: A Review, Shanthi Narla, Githa Rahmayunita, Rinadewi Astriningrum, Tor Shwayder, Ariyati Yosi, Henry W. Lim

Journal of General - Procedural Dermatology and Venereology Indonesia

Research has begun to illustrate a favorable efficacy and side-effect profile for many systemic agents used in pediatric dermatological conditions (i.e. atopic dermatitis, psoriasis, scleroderma, alopecia areata, chronic spontaneous urticaria, autoimmune blistering disorders, and hidradenitis suppurativa) despite not having extensive randomized clinical trials. The purpose of this article is to summarize the available data on the treatment regiments, safety, and efficacy of systemic immunosuppressants, including the newer biologics, focusing on the most up-to-date systematic reviews or randomized clinical trials. The review demonstrates that many of the present studies lack data on long-term efficacy and consist of small patient populations. Further …

A Case Of Ana-Negative Systemic Sclerosis Treated With Methylprednisolone, Carminda P. Rogacion, Veronica S, Uy, Reynaldo L. Ugalde, Emmerson Gale S. Vista

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Systemic sclerosis is a multi-systemic disease characterized by excessive fibrosis, inflammation, and vasculopathy. Common clinical features include skin thickening, telangiectasias, salt and pepper skin, beak-shaped nose, and microstomy. We report a case of ANA-negative systemic sclerosis in a male patient.

Case illustration: Our patient presented with a 10-month history of diffuse hyperpigmentation, skin tightening and decreased mouth aperture, accompanied by digital ulcers, hypopigmented macules and violaceous discoloration of the digits upon exposure to cold temperature. Punch biopsy done revealed mild acanthosis of the epidermis with basal cell layer hyperpigmentation, vacuolar alteration and thickening of the basement membrane …

Recurrent Basal Cell Carcinoma With Maxillary Bone Invasion, Adhimukti T. Sampurna, Eva Riani, Inge Ade Kristanti, Yayi Dwina, Kuniaki Ohara

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Basal cell carcinoma (BCC) is a malignant, slow growing, and locally invasive skin tumor. Advanced and neglected BCC may invade adjacent structures. The 5-year recurrence rates of facial BCCs are 4.1% after excision and 2.5% after Mohs Micrographic Surgery (MMS). The number of BCC cases invading the bones of the head and neck region is limited.

Case Illustration: A 75-year-old male complained of bleeding and ulcer enlargement on the right cheek expanding to the right nasal ala for 1 month. The patient had a history of an enlarged and painful lenticular nodule with a hyperpigmented spot that …

Treatment Of Multibacillary Leprosy Following The Development Of Dapsone Hypersensitivity Syndrome, Sudarsono Sudarsono

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: World Health Organization (WHO) multi-drug therapy (MDT) is the current standard treatment for leprosy. A wide range of frequency of adverse effects caused by MDT has been reported. Dapsone hypersensitivity syndrome (DHS) is a serious adverse effect caused by dapsone. Prompt withdrawal of dapsone is important aspect in the management of DHS. Alternative regimens are needed to treat leprosy patient with DHS.

Case Illustration: A 37-year-old man with multibacillary (MB) leprosy developed DHS in 39 days after the initiation of WHO MDT. Dapsone was withdrawn and methylprednisolone of 75 mg/day was prescribed. Twelve days after admission the …

Effect Of 3d Printed Tablet Shape On Drug Release Profile, Christina Gedeon

Theses

There is a growing interest in utilizing additive manufacturing (AM) as a manufacturing tool to develop oral tablets for personalized medicine. This ultimate goal in mind, this study explores the feasibility of extrusion-based fused deposition modeling (FDM) to 3D print oral tablets with tunable design to control drug release profile. Tablets are printed using poly(vinyl alcohol) (PVA) loaded with model drugs: acetaminophen and caffeine. Hot melt extrusion (HME) is used to fabricate PVA filaments loaded with acetaminophen and caffeine. These filaments are used to fabricate a range of tablets with varying designs to prepare immediate and delayed release tablets. Thermal …

Professional Development For Clerkship Administrators: A 16-Year Overview Of The Clerkship Administrator Certificate Program, Donnita Pelser, Cathy Chavez, Lindsey Allison, Virginia Cleppe, Gary L Beck Dallaghan

Medical Education Faculty Publications

Background: Increasing accreditation requirements as well as transformations in medical school curricula necessitate administrative staff who are not only invested in the clerkship coordinator role but also view what they do as a career. To date, there has been a lack of professional development opportunities for clerkship administrators.

Methods: In 2003, the Central Group on Educational Affairs of the Association of American Medical Colleges recognized a need for professional development for clerkship administrators. The Clerkship Administrator Certificate Program emerged from that decision and presented for the first time in 2004 in Omaha, Nebraska. This article provides an overview of the …