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2022

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Full-Text Articles in Medicine and Health Sciences

Reduced Serum Concentrations Of Reactive Oxygen And Nitrogen Species Following Strenuous Exercise In The Heat Are Not Associ-Ated With An Upregulation In Serum Antioxidative Capacity, Sebastian Keller, Hannah Lisa Notbohm, Wilhelm Bloch, Moritz Schumann Dec 2022

Reduced Serum Concentrations Of Reactive Oxygen And Nitrogen Species Following Strenuous Exercise In The Heat Are Not Associ-Ated With An Upregulation In Serum Antioxidative Capacity, Sebastian Keller, Hannah Lisa Notbohm, Wilhelm Bloch, Moritz Schumann

Baltic Journal of Health and Physical Activity

Introduction: Reactive oxygen and nitrogen species (RONS) are produced as a response to exercise and play a part in guiding the adaptive response to physical training. Exercise in the heat has been shown to further increase accumulation of RONS in systemic circulation; however, a high antioxidative response or heat acclimatization mechanisms could attenuate this response. In a previous study, we found reduced RONS concentrations in trained athletes following strenuous cycling in the heat. Therefore, this secondary analysis assessed whether these reduced RONS serum concentrations are induced by an increased serum antioxidant capacity. Methods: Twelve male cyclists (V̇O2peak: 60 …


Small Extracellular Vesicle-Mediated Itgb6 Sirna Delivery Downregulates The Αvβ6 Integrin And Inhibits Adhesion And Migration Of Recipient Prostate Cancer Cells, Shiv Ram Krishn, Vaughn Garcia, Nicole M Naranjo, Fabio Quaglia, Christopher D Shields, Maisha A Harris, Andrew V Kossenkov, Qin Liu, Eva Corey, Dario C Altieri, Lucia R Languino Dec 2022

Small Extracellular Vesicle-Mediated Itgb6 Sirna Delivery Downregulates The Αvβ6 Integrin And Inhibits Adhesion And Migration Of Recipient Prostate Cancer Cells, Shiv Ram Krishn, Vaughn Garcia, Nicole M Naranjo, Fabio Quaglia, Christopher D Shields, Maisha A Harris, Andrew V Kossenkov, Qin Liu, Eva Corey, Dario C Altieri, Lucia R Languino

Department of Cancer Biology Faculty Papers

The αVβ6 integrin, an epithelial-specific cell surface receptor absent in normal prostate and expressed during prostate cancer (PrCa) progression, is a therapeutic target in many cancers. Here, we report that transcript levels of ITGB6 (encoding the β6 integrin subunit) are significantly increased in metastatic castrate-resistant androgen receptor-negative prostate tumors compared to androgen receptor-positive prostate tumors. In addition, the αVβ6 integrin protein levels are significantly elevated in androgen receptor-negative PrCa patient derived xenografts (PDXs) compared to androgen receptor-positive PDXs. In vitro, the androgen receptor-negative PrCa cells express high levels of the αVβ6 integrin compared to androgen receptor-positive PrCa cells. Additionally, …


Improving Handwashing Behavior Of School-Age Children Through A Game-Based Educational Program, Ikbal Fradianto, Arief Andriyanto, Nur Akbar, Nita Arisanti Yulanda, Bahtiar Bahtiar Dec 2022

Improving Handwashing Behavior Of School-Age Children Through A Game-Based Educational Program, Ikbal Fradianto, Arief Andriyanto, Nur Akbar, Nita Arisanti Yulanda, Bahtiar Bahtiar

ASEAN Journal of Community Engagement

Handwashing plays an essential role in overcoming health problems. Washing hands is a straightforward exercise but will not be done if not adequately informed and drilled on it. School-age children are a vulnerable group relative to health problems, but at the same time, is an excellent group to be given appropriate education. Educating school- age children on the importance of washing their hands is critical to improving health behavior. This community-based research aims to increase school-age children’s handwashing knowledge, attitudes, and practices using a game-based educational program. As a result, there are improvements in the handwashing behavior of around a …


Learning Life Skills Through English Materials: Integrating Life Skills In English Pedagogy, Laela Hikmah Nurbatra, Masyhud Masyhud, Hartono Hartono Dec 2022

Learning Life Skills Through English Materials: Integrating Life Skills In English Pedagogy, Laela Hikmah Nurbatra, Masyhud Masyhud, Hartono Hartono

ASEAN Journal of Community Engagement

John Dewey once said that “education is not an affair of ‘telling’ and being told, but an active and constructive process.” Accordingly, pedagogical processes should not simply be conducted by traditional lecturing, but rather, they should be constructive processes that gradually build the meaning-making process of the children through their active participation. Therefore, this paper aims to suggest materials that integrate English learning and LSE that are specifically designed for Indonesian children. As a follow-up project from the previous program, the current community service focuses on the implementation of life skills education (LSE) by integrating LSE with English learning in …


Assessment Of The Effects Of Edentulousness On Temporomandibular Components By Using Cone Beam Computed Tomography, Büşra Arıkan, Numan Dedeoğlu, Şuayip Burak Duman Dec 2022

Assessment Of The Effects Of Edentulousness On Temporomandibular Components By Using Cone Beam Computed Tomography, Büşra Arıkan, Numan Dedeoğlu, Şuayip Burak Duman

Journal of Dentistry Indonesia

Objective: The aim of this study is to evaluate the effects of edentulousness on the temporomandibular joint using cone beam computed tomography (CBCT). Methods: In this study, CBCT images were evaluated in a total of 48 patients (24 dentulous, 24 edentulous). Ninety-six temporomandibular joint CBCT images were examined. Eminence inclination, condyle head widths and joint space were measured and statistically compared between the edentulous and dentulous groups. Results: The articular eminence inclination value the mediolateral width of the condyle and the anteroposterior width of the condyle were found significantly higher in the dentulous group than in the edentulous group. …


Effect Of Preflaring On Accuracy Of Endodontic Length Determination By Four Electronic Apex Locators, Arash Izadi, Maliheh Bayandari, Ezatolah Kazeminejad Dec 2022

Effect Of Preflaring On Accuracy Of Endodontic Length Determination By Four Electronic Apex Locators, Arash Izadi, Maliheh Bayandari, Ezatolah Kazeminejad

Journal of Dentistry Indonesia

Objective: Root canal anatomy significantly impacts the working length determination. This study aimed to investigate the effect of the preflaring technique on the accuracy of four electronic apex locators. Methods: Forty-five single-canal central maxillary teeth were selected. The working length was measured before and after the coronal preparation by four types of electronic apex locators in the range of ±0.5 and ±1 mm matched for the apical constriction. The actual working length was calculated under a microscope. Data were analyzed using ICC and paired t-tests in SPSS16. A p < 0.05 was considered significant. Results: The accuracies of Root ZX, DTE, Denjoy, and Coxo apex …


Three-Dimensional Evaluation Of The Mandibular Lingula On Cone-Beam Computed Tomographic Images In The Turkish Population, Zerrin Unal Erzurumlu, Damla Torul Dec 2022

Three-Dimensional Evaluation Of The Mandibular Lingula On Cone-Beam Computed Tomographic Images In The Turkish Population, Zerrin Unal Erzurumlu, Damla Torul

Journal of Dentistry Indonesia

Objective: The purpose of this study was to provide morphometric and anatomical data for mandibular lingula (Li) in The Turkish population using three dimensional-cone beam computed tomography (3D-CBCT) images. Methods: CBCT images of the patients taken between July 2020 and March 2021, were retrieved from the archival records. A total of 100 Li’s of 50 patients who met the criteria of this study were evaluated. The distances between the tip of the Li and ramal landmarks/occlusal plane were measured and the shape of the Li was evaluated on 3D-CBCT images. Results: CBCT images of the 50 patients (19 males and …


Effect Of Different Surface Treatments And Application Times On Shear Bond Strength Between Polyetheretherketone And Composite Resin, Alper Ozdogan, Basak Topdagi Dec 2022

Effect Of Different Surface Treatments And Application Times On Shear Bond Strength Between Polyetheretherketone And Composite Resin, Alper Ozdogan, Basak Topdagi

Journal of Dentistry Indonesia

Objective: To investigate the effect of various surface treatments and different application times on shear bond strength between polyetheretherketone and composite resin. Methods: A total of 110 disc-shaped polyetheretherketone specimens were randomly divided into 9 groups and 4 different surface treatments (control, sandblasting, tribochemical silica coating, sulfuric acid) were applied. The sandblasting, tribochemical silica coating, and sulfuric acid processes were performed 3 different times (10s, 15s, 20s). Then, the composite resins were applied to the treated surfaces of the polyetheretherketone specimens. The shear bond strength test and scanning electron microscopy analysis were performed. The data were statistically analyzed using …


Comparison Of Ultrasonography And Cone Beam Computed Tomography In The Differential Diagnosis Of Periapical Lesions: A Prospective Radiopathological Study, Gozde Serindere, Ceren Aktuna Belgin, Mert Bulte, Didar Gursoy, Fariz Salimov Dec 2022

Comparison Of Ultrasonography And Cone Beam Computed Tomography In The Differential Diagnosis Of Periapical Lesions: A Prospective Radiopathological Study, Gozde Serindere, Ceren Aktuna Belgin, Mert Bulte, Didar Gursoy, Fariz Salimov

Journal of Dentistry Indonesia

Objective: The aim of this study is to evaluate the correlation between ultrasonography (USG) and cone beam computed tomography (CBCT) and the accuracy between histopathological diagnosis and preliminary diagnosis in the diagnosis of periapical lesion. Methods: 20 patients with periapical lesion in the jaw, were included in the study. The presence of expansion or perforation and dimensions of the lesion were performed with CBCT. In the examination of the lesion with USG, shape, echogenicity, vascularization of the lesion and the presence of buccal expansion and perforation, were determined. Subsequently, a biopsy was taken from the lesion for histopathological examination and …


Stereomicroscopic Evaluation Of Dentinal Microcracks After Instrumentation Of Curved Canal With Rotary Files In Two Motions, Nupur Vasava, Shreya Modi, Chintan Joshi, Sweety Thumar, Anisha Parmar, Kruti Jadawala Dec 2022

Stereomicroscopic Evaluation Of Dentinal Microcracks After Instrumentation Of Curved Canal With Rotary Files In Two Motions, Nupur Vasava, Shreya Modi, Chintan Joshi, Sweety Thumar, Anisha Parmar, Kruti Jadawala

Journal of Dentistry Indonesia

Objective: This study aimed to examine the effects of three distinct file systems with two motion types—rotary and reciprocation—on the development of dentinal microcracks after root canal preparation using a stereomicroscope. Methods: Sixty mandibular molars with a curvature of 30° were decoronated and divided into three groups (Vortex Blue, Mtwo, and ProTaper Next) and two subgroups (rotary and reciprocating motions). The samples were then instrumented with the files, dyed with 1% methylene blue dye, and sectioned horizontally at 3, 6, and 9 mm from the root apex. The dentinal microcracks were inspected using a stereomicroscope at 40× magnification. One-way analysis …


Evaluation Of Dentoskeletal And Pharyngeal Airway Changes After Treatment With Twin Block And Monoblock Appliance In Growing Patients, Esra Genc, Ahmet Karaman, Gülşah Püskül Dec 2022

Evaluation Of Dentoskeletal And Pharyngeal Airway Changes After Treatment With Twin Block And Monoblock Appliance In Growing Patients, Esra Genc, Ahmet Karaman, Gülşah Püskül

Journal of Dentistry Indonesia

Objective: To compare of pharyngeal airway dimensions and dentoskeletal changes after treatment with twin block (TWB) and monoblock (MB) appliance in growing patients. Methods: The sample was comprised of a total of 72 patients at the ages of 10 to 13. The TWB group consisted of 36 patients (22 females, 14 males, mean age: 11.9±1.5) and MB group consisted of 36 patients (18 females, 18 males, mean age: 11.8±1.2). The linear and angular measurements were evaluated on lateral cephalometric radiographs at beginning (T0) and end of treatment (T1). Results: The amounts of increase in the inferior airway space, L1xNB, IMPA …


Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila Dec 2022

Clinical And Radiographic Features Of Nevoid Basal Cell Carcinoma Syndrome: A Case Report, G Subhas Babu, Devika S. Pillai, Shruthi Hegde, Padmaraj Hegde, Vidya Ajila

Journal of Dentistry Indonesia

Nevoid Basal Cell Carcinoma Syndrome, also called as Gorlin Gotz syndrome is an autosomal dominant disorder characterized by the presence of multiple odontogenic keratocysts (OKCs) of the jaw, basal cell carcinomas and skeletal anomalies. Presence of multiple OKCs is the first clinical manifestation in majority of the cases. Early diagnosis and treatment are of utmost importance in reducing the severity of this syndrome. We hereby report a rare case of Gorlin Goltz syndrome in a 28 years old female patient who presented with multiple cystic lesions in the jaws. Present case also highlights the clinical, radiographic and histopathologic features of …


Endodontic Management Of An Unusual Mandibular First Molar With Six Canals: A Case Report And Systematic Review, Sarah Ahmad, Syed Mukhtar -Un- Nisar Andrabi, Ashok Kumar, Surendra Kumar Mishra, Rajendra Kumar Tewari Dec 2022

Endodontic Management Of An Unusual Mandibular First Molar With Six Canals: A Case Report And Systematic Review, Sarah Ahmad, Syed Mukhtar -Un- Nisar Andrabi, Ashok Kumar, Surendra Kumar Mishra, Rajendra Kumar Tewari

Journal of Dentistry Indonesia

The permanent mandibular first molar is frequently involved in conventional root canal treatment due to its function and position in the oral cavity. Additional root canals mandate accurate diagnosis and conservative management to prevent any procedural errors. The first independent middle mesial canal incidence was verified in mandibular molars in 1974, with a global incidence of 10.8–27.0%. Reporting of the middle distal canal in the endodontic literature is scarce, with an incidence of 0.2–3%. The present case report describes the endodontic management of an unusual permanent mandibular first molar with three canals in the mesial and distal roots, diagnosed with …


Modified Maxillary Palatal Ramp Prosthesis To Guide Mandibular Deviation Following Segmental Mandibulectomy For Squamous Cell Carcinoma, Manu Rathee, Sujata Chahal, Maqbul Alam, Prachi Jain Dec 2022

Modified Maxillary Palatal Ramp Prosthesis To Guide Mandibular Deviation Following Segmental Mandibulectomy For Squamous Cell Carcinoma, Manu Rathee, Sujata Chahal, Maqbul Alam, Prachi Jain

Journal of Dentistry Indonesia

Benign or malignant tumor is one of the frequent causes of resection of the mandible. The extent and location of the tumor decides the mode of treatment of the neoplastic lesion. Surgical removal of oral neoplasm leads to an extensive resection of the mandible along with the associated structures. Objective: This case report describes the use of palatal ramp prosthesis to guide the mandible during movements and restore a stable occlusal relationship with an additional acrylic buccal pad to achieve partial esthetics. Case Report: A 30-years-old female patient reported with the inability to chew food following the mandibular resection of …


Prevalence And Evaluation Of Multidrug Resistance Pattern Of Pseudomonas Aeruginosa Among Critical And Non-Critical Areas At A Tertiary Care Hospital Of Multan, Romah Ishfaq, Hubza Ruatt Khan, Mehvish Javeed, Muhammad Ikrama Tanveer, Asma Ashraf Dec 2022

Prevalence And Evaluation Of Multidrug Resistance Pattern Of Pseudomonas Aeruginosa Among Critical And Non-Critical Areas At A Tertiary Care Hospital Of Multan, Romah Ishfaq, Hubza Ruatt Khan, Mehvish Javeed, Muhammad Ikrama Tanveer, Asma Ashraf

Journal of Bioresource Management

Pseudomonas aeruginosa is an extremely wide spread microorganism linked to nosocomial illnesses. Effective inspection of variations in antimicrobial resistance patterns of P. aeruginosa is vital for selecting suitable antimicrobial drugs for pragmatic treatment. The current research has been performed for assessing antimicrobial sensitivity profile of P. aeruginosa isolated as of a variety of medical specimens collected from critical and non-critical admitted patients of Nishtar Hospital, Multan. The isolates were detected utilizing standard lab practices, as well as the sensitivity was examined employing Kirby-Bauer disk diffusion method corresponding to Clinical and Laboratory Standard Institute (CLSI) recommendations 2019. Out of 373 samples, …


A Pilot Intervention Combining Assessment And Feedback With Communication Training And Behavioral Nudges To Increase Hpv Vaccine Uptake., Andrea Bradley-Ewing, Brian R. Lee, Jason N. Doctor, Georgann Meredith, Kathy Goggin, Angela Myers Dec 2022

A Pilot Intervention Combining Assessment And Feedback With Communication Training And Behavioral Nudges To Increase Hpv Vaccine Uptake., Andrea Bradley-Ewing, Brian R. Lee, Jason N. Doctor, Georgann Meredith, Kathy Goggin, Angela Myers

Manuscripts, Articles, Book Chapters and Other Papers

Human papillomavirus (HPV) causes >40,000 cancer diagnoses each year, yet vaccination rates remain low because widespread implementation of strategies to increase vaccinations has not occurred. Behavioral nudges have demonstrated efficacy in improving uptake of desired behaviors in health care settings but have not been tested for increasing HPV vaccinations. We assessed the impact of an intervention combining behavioral nudges with other proven strategies (i.e., assessment and feedback, provider communication training) on HPV vaccination rates and parental satisfaction in four Midwestern pediatric, outpatient practices. Practices were randomly assigned to receive either assessment and feedback or assessment and feedback combined with vaccine …


Clinicodemographic And Laboratory Characteristics Of Cutaneous Tuberculosis At Tertiary Referral Hospital In West Java, Indonesia, Anisa Sediadini, Hendra Gunawan, Risa Miliawati Nurul Hidayah Dec 2022

Clinicodemographic And Laboratory Characteristics Of Cutaneous Tuberculosis At Tertiary Referral Hospital In West Java, Indonesia, Anisa Sediadini, Hendra Gunawan, Risa Miliawati Nurul Hidayah

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Cutaneous tuberculosis (TB) is a chronic infectious disease affecting the skin caused by Mycobacterium tuberculosis (M. tuberculosis). It constitutes 1–1.5% of extrapulmonary TB, with Indonesia being the third-highest TB burden country worldwide. Cutaneous TB is difficult to diagnose due to its varied presentations. This study aimed to describe the clinicodemographic and laboratory characteristics of cutaneous TB in a tertiary referral hospital in West Java, Indonesia.

Methods: This was a descriptive retrospective cross-sectional study. Data were obtained from the medical record of patients with cutaneous TB in the Tropical Dermatology Clinic of Hasan Sadikin Hospital Bandung, West Java, …


Clinicodemographic Characteristics Of Cutaneous Larva Migrans: A 10-Year Study In Tertiary Referral Hospital-West Java, Indonesia, Tuesi Fredella Avissa, Hendra Gunawan, Risa Miliawati Nurul Hidayah Dec 2022

Clinicodemographic Characteristics Of Cutaneous Larva Migrans: A 10-Year Study In Tertiary Referral Hospital-West Java, Indonesia, Tuesi Fredella Avissa, Hendra Gunawan, Risa Miliawati Nurul Hidayah

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Cutaneous larva migrans (CLM) is the most common helminthic dermatosis caused by animal hookworm, commonly reported in tropical and subtropical regions. Most studies are on travellers returning from endemic areas, paradoxically very few reports in endemic countries, including Indonesia, where they mostly take place. This study aimed to describe the demographic and clinical characteristics of CLM patients for 10 years in a tertiary referral hospital in West Java, Indonesia.

Methods: This was a descriptive retrospective cross-sectional study. The data were obtained from the medical record of patients who was diagnosed as CLM in Tropical Dermatology Clinic Hasan …


The Difference In Transepidermal Water Loss (Tewl) Values Between Sun-Exposed And Non-Sun-Exposed Skin Among Male Medical Students, Ihsany Arafiasetyanto Prihadi, Endra Yustin Ellistasari, Arie Kusumawardani Dec 2022

The Difference In Transepidermal Water Loss (Tewl) Values Between Sun-Exposed And Non-Sun-Exposed Skin Among Male Medical Students, Ihsany Arafiasetyanto Prihadi, Endra Yustin Ellistasari, Arie Kusumawardani

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Transepidermal Water Loss (TEWL) is the amount of water released from the human body into the atmosphere through a diffusion process per unit of time. Changes in TEWL indicate impaired skin barrier function. Exposure to ultraviolet light for an extended period can cause photoaging, characterized by rough and dry skin (xerosis cutis). TEWL will increase significantly in the skin exposed to ultraviolet radiation. This study aims to determine the difference in the TEWL values among male medical students in the sun-exposed and non-sun-exposed skin areas.

Methods: An analytical observational cross-sectional study was conducted at the Dermatology and …


Risk Factors For Hiv-Positive Status In Condyloma Acuminata, Izazi Hari Purwoko, Putri Laksmi Karim, Suroso Adi Nugroho, Theresia Toruan, Fitriani . Dec 2022

Risk Factors For Hiv-Positive Status In Condyloma Acuminata, Izazi Hari Purwoko, Putri Laksmi Karim, Suroso Adi Nugroho, Theresia Toruan, Fitriani .

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Condyloma acuminata (CA) is a sexually transmitted infection (STI) caused by human papillomavirus (HPV), especially types 6 and 11. The number of HPV infections increases in immunosuppressed conditions, such as human immunodeficiency virus (HIV) infection. Risk factors in CA patients such as gender, sexual partner, sexual orientation, and sexual intercourse can increase HIV status.

Methods: This is a descriptive-analytic study with a cohort retrospective design. The subjects are all CA patients who visited the polyclinic STI Dr. Mohammad Hoesin, General Hospital, Palembang, Indonesia, between 2016-2020. The number of CA patients included in the study were 115 patients …


Seborrheic Keratosis Profile At Dr. Hasan Sadikin Central General Hospital Bandung 2015-2019, Eva Krishna Sutedja, Resti Gradia, Tri Aswila Latifah Dec 2022

Seborrheic Keratosis Profile At Dr. Hasan Sadikin Central General Hospital Bandung 2015-2019, Eva Krishna Sutedja, Resti Gradia, Tri Aswila Latifah

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Seborrheic keratosis (SK) is adults’ most prevalent benign skin tumor. SK originates from the proliferation of keratinocyte cells with varying morphology and degree of pigmentation. The lesions often resemble other types of malignancy. There are still many discrepancies in SK in Indonesia; hence, SK needs further understanding. This study aimed to describe the profile of seborrheic keratosis cases based on age, sex, location of lesions, and therapy at Dr. Hasan Sadikin Central General Hospital, Bandung, for five years

Methods: This was a retrospective descriptive study with total sampling. Secondary data were collected from medical records of SK …


Correlation Between Serum 25 Hydroxy-Vitamin D Levels And The Worst Pain Intensity In Postherpetic Neuralgia, Wizar Putri Mellaratna, Nelva K. Jusuf, Ariyati Yosi Dec 2022

Correlation Between Serum 25 Hydroxy-Vitamin D Levels And The Worst Pain Intensity In Postherpetic Neuralgia, Wizar Putri Mellaratna, Nelva K. Jusuf, Ariyati Yosi

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Postherpetic neuralgia (PHN) is persistent pain in the affected dermatome that occurs more than three months after the eruption of the herpes zoster has disappeared. Vitamin D has a role in Schwann cell regeneration and stimulates the release of nerve growth factors.

Methods: Blood sampling was performed to test serum 25(OH)D levels. Patients filled out their worst pain intensity using the Zoster Brief Pain Inventory questionnaire. The score was reported in Likert score (0-10), 0 indicating no pain and 10 indicating the most severe pain. Spearman correlation test was used, and p 0.05) and PHN durations (p …


Torch Re-Activation Concomitant With Drug-Induced Hypersensitivity Syndrome Shows Erythema Multiforme-Like And Vasculitis Clinical Features, Windy Keumala Budianti, Rahadi Rihatmadja, Izzah Aulia, Isaak Effendy Dec 2022

Torch Re-Activation Concomitant With Drug-Induced Hypersensitivity Syndrome Shows Erythema Multiforme-Like And Vasculitis Clinical Features, Windy Keumala Budianti, Rahadi Rihatmadja, Izzah Aulia, Isaak Effendy

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Drug-induced hypersensitivity syndrome (DIHS) can be associated with cytomegalovirus (CMV) infection, besides induced by drugs. We report a case of DIHS with prolonged atypical clinical features and vasculitis precipitated by drug allergy, CMV, and other viral infections.

Case illustration: A 54-year-old female presented with generalized follicular erythematous papules and waxy palmoplantar keratoderma since one month before admission. The symptoms started as a purpuric lesion on the upper extremities, spreading as erythematous papules on the trunk with facial edema, accompanied by fever and chronic cough. She had been previously treated with ambroxol and cephalosporin. Cutaneous drug allergy reaction …


A Case Of Longitudinal Melanonychia In A Child: Benign Or Malignant?, Heffi Anindya Putri, Ennesta Asri, Qaira Anum Dec 2022

A Case Of Longitudinal Melanonychia In A Child: Benign Or Malignant?, Heffi Anindya Putri, Ennesta Asri, Qaira Anum

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Longitudinal melanonychia (LM) describes a longitudinal brown-to-black band of discoloration affecting a finger, thumb, or toenail. Discoloration of the nails can be a sign of benign or malignant nail disorders. Although nail melanoma rarely occurs in children, health practitioners should be aware of melanonychia. Dermoscopy and histopathology are helpful in the diagnosis.

Case Illustration: A case of LM in a thirteen-year-old girl was reported with a complaint of brownish-black discoloration, sometimes painful, on her right thumb since 1 year ago. She had no history of trauma, nail damage, or bleeding tendency. Dermatological examination found a homogeneous brownish-black …


Haircare Practice And Dandruff Problems Among Indonesian Medical Students, Jessica Rosemary Wikanto, Lorettha Wijaya, Yunisa Astiarani, Regina Regina Dec 2022

Haircare Practice And Dandruff Problems Among Indonesian Medical Students, Jessica Rosemary Wikanto, Lorettha Wijaya, Yunisa Astiarani, Regina Regina

Journal of General - Procedural Dermatology & Venereology Indonesia

Background: Dandruff is an understated hair and scalp problem that causes striking social and concentration issues among medical students. Haircare practice among them may or may not be related to the dandruff incident.

Methods: A cross-sectional study was conducted on 74 pre-clinical medical students at Atma Jaya Catholic University of Indonesia. Trained health staff assessed dandruff prevalence by physical examination, and the haircare practice was measured using a questionnaire. Bivariate analysis was utilized to assess the association between haircare practice and dandruff prevalence’s.

Result: Among respondents, 85.1% of them have dandruff. Respondents who shampooed less than five …


Twitter Sentiment Analysis: Applications In Healthcare And Finance, Jiali Wang Dec 2022

Twitter Sentiment Analysis: Applications In Healthcare And Finance, Jiali Wang

Dissertations

This research explores the influence of Twitter sentiment on healthcare and finance industries. It assesses how Twitter sentiment and culture measure influence COVID-19 statistics, and it investigates the impact of Twitter sentiment on S&P 1500 stock mispricing. Furthermore, it examines how tweet sentiment predicts major industry returns.

The first part examines how Hofstede’s Culture Dimensions (HCD) and Twitter economic uncertainty index (TEU) relate to COVID-19 infection rate and death rate. The results show certain aspects in HCD, such as power distance index (PDI) and masculinity (MAS) both are negatively and significantly associated with the infection rate, while indulgence (IVR) and …


Cutaneous Adverse Drug Reaction Among Hiv-Infected Patients Starting Antituberculosis Treatment, Alvina Widhani, Teguh Harjono Karjadi, Evy Yunihastuti, Desi Salwani, Angga Pramudita, Saut Horas Nababan, Mirna Nurasri Praptini, Prionggo Mondrowinduro Dec 2022

Cutaneous Adverse Drug Reaction Among Hiv-Infected Patients Starting Antituberculosis Treatment, Alvina Widhani, Teguh Harjono Karjadi, Evy Yunihastuti, Desi Salwani, Angga Pramudita, Saut Horas Nababan, Mirna Nurasri Praptini, Prionggo Mondrowinduro

Jurnal Penyakit Dalam Indonesia

Introduction. Treatment of tuberculosis (TB) in HIV patients is complicated due to numerous comorbidities and possible adverse effects. One of which is cutaneous adverse drug reaction (CADR). This adverse event is often difficult to manage because of multiple medications the patients get. The objective of this study was to know the prevalence and risk factors of CADR among HIV-infected patients starting anti-TB treatment. Methods. This retrospective study reviewed data from medical records of new patients at Working Group on AIDS outpatient clinic at Cipto Mangunkusumo Hospital, Indonesia in January 2008-December 2010 that had started anti-TB treatment. Risk factors of CADR …


Value Of Heart Rate Variability, Neutrophil-Lymphocyte Ratio And Quality Of Life Of Patients With Depressive Symptoms In Acute Myocardial Infarction, Hamzah Shatri, Mizanul Adli, Muhadi Muhadi, Murdani Abdullah, Cosphiadi Irawan, Rudi Putranto, Sukamto Koesnoe, Ika Prasetya Wijaya Dec 2022

Value Of Heart Rate Variability, Neutrophil-Lymphocyte Ratio And Quality Of Life Of Patients With Depressive Symptoms In Acute Myocardial Infarction, Hamzah Shatri, Mizanul Adli, Muhadi Muhadi, Murdani Abdullah, Cosphiadi Irawan, Rudi Putranto, Sukamto Koesnoe, Ika Prasetya Wijaya

Jurnal Penyakit Dalam Indonesia

Introduction. Major depression criteria can be found in more than 20% of coronary heart patients and more than 30% acute coronary syndrome patients have significant depressive symptoms. Several studies have shown that reduction of hearth rate variability (HRV) and enhancement of neutrophil lymphocyte ratio (NLR) can cause enhancement of morbidity and mortality in myocardial infarction patients. On the other hand, depression can cause reduction of HRV, enhancement of NLR and reduction of quality of life. This study aimed to determine differences in HRV, NLR and quality of life between acute myocardial infarction (AMI) patients with depressive symptoms and AMI patients …


Association Between Early Antibiotic Administration And In-Hospital Mortality In Moderate And Severe Covid-19 Patients, Lie Khie Chen, Jason Nathanael, Sharifah Shakinah, Adeline Pasaribu, Robert Sinto, Leonard Nainggolan, Adityo Susilo Dec 2022

Association Between Early Antibiotic Administration And In-Hospital Mortality In Moderate And Severe Covid-19 Patients, Lie Khie Chen, Jason Nathanael, Sharifah Shakinah, Adeline Pasaribu, Robert Sinto, Leonard Nainggolan, Adityo Susilo

Jurnal Penyakit Dalam Indonesia

Introduction. Patients with moderate and severe COVID-19 generally receive antibiotic therapy with consideration of the possibility of co-infection or secondary bacterial infection which clinically is difficult to distinguish from COVID-19 symptoms. Overuse of antibiotics can lead to an increased risk of bacterial resistance to antibiotics which is associated with poor outcomes in COVID-19 patients. This study aimed to assess the effect of early antibiotic administration on mortality in moderate and severe COVID-19 patients. Methods. An observational study with a retrospective cohort design was conducted at Dr. Cipto Mangunkusumo Hospital. Data were obtained from medical records of patients admitted from March …


Determinant Factors Of Cognitive Frailty In Elderly Patients, Valencia Santoso, Rensa Rensa Dec 2022

Determinant Factors Of Cognitive Frailty In Elderly Patients, Valencia Santoso, Rensa Rensa

Jurnal Penyakit Dalam Indonesia

Introduction. Physical frailty and cognitive impairment have a strong relationship and there are differences in factors associated with cognitive frailty. This research aimed to determine the prevalence of cognitive frailty and identify factors associated with cognitive frailty in the elderly population in hospital polyclinic. Methods. A cross-sectional study with secondary data on patients aged ≥60 years in the Internal Medicine Polyclinic of Atma Jaya Hospital, Jakarta, from May 2020 to May 2021. The independent variables of this study were age, cardiovascular disease, type 2 diabetes mellitus, dyslipidemia, risk of malnutrition, risk of depression, and functional status. The alternative criteria by …