Medicine and Health Sciences Commons^™

The Impact Of Co-Active Coaching On Physically Inactive 12 To 14 Year Olds In Ontario, Paul Gorczynski, Jennifer Irwin, Don Morrow

Donald Morrow

No abstract provided.

Life Coaching As An Intervention For Individuals With Obesity, Courtney Newnham-Kanas, Jennifer Irwin, Don Morrow

Donald Morrow

No abstract provided.

Public Health Informatics, Ardis Hanson, Bruce Levin, David Scott

Bruce Lubostsky Levin, DrPH, MPH

No abstract provided.

Disease Prevention And Health Promotion, Peter Hurd, Bruce Levin, Ardis Hanson, William Lang

Bruce Lubostsky Levin, DrPH, MPH

When people think of public health, they often think of the development of epidemiology and a famous public health story about John Snow in 1854. What he did was to map the cholera cases in London and then talk with the people to look for common links between their behaviors and the disease. ...Ever since John Snow removed the pump handle from the cholera infected well in London, heralding the start of population-based health care, the world has struggled with the realities of health promotion and disease prevention.

Introduction To Public Health In Pharmacy, Bruce Levin, Peter Hurd, Ardis Hanson

Bruce Lubostsky Levin, DrPH, MPH

This book provides a comprehensive introduction to public health from a pharmacy perspective. Organized into three main sections, Part I presents concepts and issues that pharmacists need in order to develop a knowledge base in public health. Part II examines the connection between pharmacy and public health services, including an overview of the different health services, evaluation and outcome assessment, financing, managed care pharmacy, and pharmacoeconomics. Part III contains chapters that illustrate key applications of public health concepts to pharmacy practice, including law and ethics, cultural perspectives, informatics, emergency preparedness, and education and training. Each chapter is co-authored by a ...

Public Health Services, David Scott, Bruce Levin, Ardis Hanson

Bruce Lubostsky Levin, DrPH, MPH

Unlike clinical care, with its focus on the individual, public health focuses on preventing disease and promoting health in communities based upon a population health analysis. Greater emphasis will be placed upon health promotion and disease prevention, the safety of communities and workers, school-based health programming, and the health of underserved and disadvantaged populations. Public health research has an increased emphasis on behavioral change to prevent risky behaviors and activities that lead to substance abuse, sexually transmitted diseases, and environmental and occupational hazards. These changes have created a broad array of new opportunities for professionals with advanced training in public ...

Behavioral Health, Tawny Bettinger, Bruce Levin, Ardis Hanson

Bruce Lubostsky Levin, DrPH, MPH

This chapter will present a brief overview of selected topics in behavioral health, emphasizing the history, epidemiology, treatment, medication adherence, and the role of the pharmacist in the delivery of behavioral health (including alcohol, drug abuse, and mental health) services. For a more thorough examination of mental health and substance abuse services delivery in the United States, see Levin, Petrila, and Hennessy (2004).

Introduction And Overview Of Pharmacy And Public Health, Peter Hurd, Bruce Levin, Ardis Hanson

Bruce Lubostsky Levin, DrPH, MPH

While there are many definitions of public health, key components include a community focus, a concern about disease prevention, and a commitment to health promotion. One of the most familiar definitions was first articulated in 1920 by C. E. A. Winslow, and was rearticulated by the Institute of Medicine in 1988: “The science and art of preventing disease, prolonging life, and promoting health and efficiency through organized community effort.” (p. 29). This approach works well for those seeking to apply public health activities to pharmacy settings.

Ssrn As An Initial Revolution In Academic Knowledge Aggregation And Dissemination, David Bray, Sascha Vitzthum, Benn Konsynski

Sascha Vitzthum

Within this paper we consider our results of using the Social Science Research Network (SSRN) over a period of 18 months to distribute our working papers to the research community. Our experiences have been quite positive, with SSRN serving as a platform both to inform our colleagues about our research as well as inform us about related research (through email and telephoned conversations of colleagues who discovered our paper on SSRN). We then discuss potential future directions for SSRN to consider, and how SSRN might well represent an initial revolution in 21st century academic knowledge aggregation and dissemination. Our paper ...

End Matter, Vol. 68 No. 4

Western North American Naturalist

No abstract provided.

Front Matter, Vol. 68 No. 4

Western North American Naturalist

No abstract provided.

Kajian Keamanan Pemakaian Obat Anti-Hipertensi Di Poliklinik Usia Lanjut Instalasi Rawat Jalan Rs Dr Sardjito, Zullies Ikawati

Majalah Ilmu Kefarmasian

Increasing age is generally followed by increasing chronic diseases so that the elderly needs much therapy using drugs for therapy of numerous diseases they have. Hyper-tension is one of diseases of which its prevalence increases along with increasing age. Most of the elderly diagnosed as having hypertension finally take therapy using anti-hypertension drugs. Physiological changes that happen to the elderly lead to use of drugs for side effect diseases of which their consumption should be considered while having anti-hypertension drugs. Changes in biological system to the elderly will af-fect the process of drug molecular interaction, which finally affects clinical efficacy ...

The Golgin Gmap210/Trip11 Anchors Ift20 To The Golgi Complex, John A. Follit, Jovenal T. San Agustin, Fenghui Xu, Julie A. Jonassen, Rajeev Samtani, Cecilia W. Lo, Gregory J. Pazour

Open Access Publications by UMass Chan Authors

Eukaryotic cells often use proteins localized to the ciliary membrane to monitor the extracellular environment. The mechanism by which proteins are sorted, specifically to this subdomain of the plasma membrane, is almost completely unknown. Previously, we showed that the IFT20 subunit of the intraflagellar transport particle is localized to the Golgi complex, in addition to the cilium and centrosome, and hypothesized that the Golgi pool of IFT20 plays a role in sorting proteins to the ciliary membrane. Here, we show that IFT20 is anchored to the Golgi complex by the golgin protein GMAP210/Trip11. Mice lacking GMAP210 die at birth ...

Bone Health And Coronary Heart Disease In Postmenopausal Women With Breast Cancer Treated With Tamoxifen: A Dissertation, Hongliu Ding

Morningside Graduate School of Biomedical Sciences Dissertations and Theses

Breast cancer, osteoporosis, and coronary heart disease (CHD) are three major threats to women’s health. Postmenopausal women with breast cancer are also at high risk for osteoporosis and CHD. Adjuvant tamoxifen therapy is not only an effective treatment for breast cancer, but has been shown to have a beneficial effect on bone and the cardiovascular system. Although tamoxifen has been convincingly demonstrated to be able to preserve bone mineral density (BMD), an unexpected increase of risk of fractures in patients treated with tamoxifen has been reported. The findings of the association of tamoxifen and CHD from previous studies were ...

Neurobiology Of Pediatric Mood Disorders:Are We There Yet, Jair C. Soares, Jean A. Frazier

Psychiatry Publications

No abstract provided.

Tax1bp1 Interacts With Papillomavirus E2 And Regulates E2-Dependent Transcription And Stability, Xiaoyu Wang, Samisubbu R. Naidu, Francis Sverdrup, Elliot J. Androphy

Open Access Publications by UMass Chan Authors

The papillomavirus E2 proteins regulate viral replication, gene transcription, and genome maintenance by interacting with other viral and host proteins. From a yeast two-hybrid screen, we identified the cellular protein Tax1BP1 as a novel binding partner of human papillomavirus type 18 (HPV18) E2. Tax1BP1 also interacts with the HPV16 and bovine papillomavirus type 1 (BPV1) E2 proteins, with the C-terminal region of Tax1BP1 interacting with the N-terminal transactivation domain of BPV1 E2. Tax1BP1 complexes with p300 and acts synergistically as a coactivator with p300 to enhance E2-dependent transcription. Using chromatin immunoprecipitation assays, we show that Tax1BP1 and E2 localize to ...

Splenic Rupture, Secondary To G-Csf Use For Chemotherapy Induced Neutropenia: A Case Report And Review Of Literature., Nehal Masood, Asim Jamal Shaikh, Wasim Ahmed Memon, Romana Idress

Section of Haematology/Oncology

Introduction: Chemotherapy Induced neutropenia is a frequent and serious complication of cytotoxic cancer treatment. Granulocyte colony stimulating factors (G-CSF) are frequently used to counter neutropenia, attempt rapid recovery of Patients and allow for continuation of treatment without compromise on dose, especially in curative malignancies. Generally regarded as safe, G-CSF use has been very rarely reported to have resulted in serious side effects, such as, splenic rupture. Case Presentation: We are reporting a case of a twenty years old man, who was being treated for T cell acute lymphoblastic leukemia and received colony stimulating factors for treatment of severe neutropenia and ...

Genotyping And Drug Resistance Patterns Of M. Tuberculosis Strains In Pakistan., Mahnaz Tanveer, Zahra Hasan, Amna R Siddiqui, Asho Ali, Akbar Kanji, Solomon Ghebremicheal, Rumina Hasan

Department of Pathology and Laboratory Medicine

Background:The incidence of tuberculosis in Pakistan is 181/100,000 population. However, information about transmission and geographical prevalence of Mycobacterium tuberculosis strains and their evolutionary genetics as well as drug resistance remains limited. Our objective was to determine the clonal composition, evolutionary genetics and drug resistance of M. tuberculosis isolates from different regions of the country.

Methods:

M. tuberculosis strains isolated (2003-2005) from specimens submitted to the laboratory through collection units nationwide were included. Drug susceptibility was performed and strains were spoligotyped.

Results:

Of 926 M. tuberculosis strains studied, 721(78%) were grouped into 59 "shared types", while 205 ...

A Selective Gβγ-Linked Intracellular Mechanism For Modulation Of A Ligand-Gated Ion Channel By Ethanol, Gonzalo E. Yevenes, Gustavo Moraga-Cid, Robert W. Peoples, Günther Schmalzing, Luis G. Aguayo

Biomedical Sciences Faculty Research and Publications

The current understanding about ethanol effects on the ligand-gated ion channel (LGIC) superfamily has been restricted to identify potential binding sites within transmembrane (TM) domains in the Cys-loop family. Here, we demonstrate a key role of the TM3–4 intracellular loop and Gβγ signaling for potentiation of glycine receptors (GlyRs) by ethanol. We discovered 2 motifs within the large intracellular loop of the GlyR α₁ subunit that are critical for the actions of pharmacological concentrations of ethanol. Significantly, the sites were ethanol-specific because they did not alter the sensitivity to general anesthetics, neurosteroids, or longer n-alcohols. Furthermore, Gβγ ...

The Relationship Between Nonword Repetition Performance And Social Behaviors In 7- To 11-Year-Old Children With Language Impairment, Bethany Lynne Hillary

Theses and Dissertations

Recent literature has suggested a link between verbal working memory and language impairment (LI) in children. There is limited research, however, about the link between verbal working memory and social behaviors in children with LI. This study was designed to explore the relationship between social behaviors (measured by the Teacher Behavior Rating Scale; Hart & Robinson, 1996) and verbal working memory abilities (measured by a 3-, 4-, and 5-syllable nonword repetition task) in children with LI. Thirty-six children (18 with LI and 18 typically developing) aged 7 to 11 years participated in the study. Children with LI were rated by teachers ...

Today - December 22, 2008, Loma Linda University

TODAY

Inside this issue:

-- Loma Linda University, Atlantic Union College explore affiliation possibilities between institutions
-- Senior vice president for development/public affairs named
-- LLUMC, BMC nursing leadership contributes to China academic week
-- Cancer survivors return to Loma Linda
-- 6:10 to the Great Southwest
-- Loma Linda University participates in community emergency response training
-- Good Samaritan awards celebrate employees who fulfill institutional mission
-- Community Christmas Fiesta held at SACHS–Norton
-- Class projects helps chronically ill kids
-- Jan Fisher retires after half a century of service to physical therapy

Ethanol Sensitivity And Tolerance Of Rat Neuronal Bk Channels: A Dissertation, Patricia M. Wynne

Morningside Graduate School of Biomedical Sciences Dissertations and Theses

BK channels are well studied targets of acute ethanol action. They play a prominent role in neuronal excitability and have been shown to play a significant role in behavioral ethanol tolerance in invertebrates. The focus of my work centers on the effects of alcohol on the BK channel and comprises studies that examine how subcellular location affects acute ethanol sensitivity and how duration of acute alcohol exposure impacts the development of rapid tolerance. My results also provide potential mechanisms which underlie acute sensitivity and rapid tolerance.

I first explore BK channel sensitivity to ethanol in the three compartments (dendrite, cell ...

Reducing The Public Health Impact Of Bovine Tuberculosis By Controlling Disease Transmission Between Cattle And White-Tailed Deer In Northwestern Minnesota, Barbara Knust

Michigan Bovine Tuberculosis Bibliography and Database

Bovine tuberculosis, caused by infection with Mycobacterium bovis, is a re-emerging zoonotic disease. It has staged a comeback by establishing infections in wildlife and cattle, creating the potential for human disease in locations where it was thought to be under control. In northwestern Minnesota, infected cattle and white-tailed deer were first discovered in 2005. A major bovine tuberculosis eradication campaign is underway in the state, with multiple efforts employed to control M. bovis infection in both cattle and deer populations. In order to effectively eradicate bovine tuberculosis in Minnesota, there is a need for better understanding of the factors that ...

Parental Hesitation As A Factor In Delayed Childhood Immunization, Karlen E. (Beth) Luthy, Renea L. Beckstrand, Neil E. Peterson

Faculty Publications

Introduction: One reason for lower immunization rates is that some parents hesitate to have their children immunized. A hesitancy questionnaire was developed to identify reasons parents hesitate in having their children immunized.

Methods: The hesitancy questionnaire was distributed from local pediatric and family practice offices and from the area's county health department. To be eligible, participants needed to be present in the clinic with a child needing a minimum of one immunization that was at least 6 months overdue.

Results: When questioned why their child was overdue for immunizations, the most common response was that participants were confused about ...

Mental Health Impact Of Disasters, Saman Faisal

Public Health Theses

It is very important to study the mental health impact of disasters to provide adequate mental health services when there is an increased demand of mental health services and a concurrent deterioration of mental healthcare capacity after disasters. This study examined the mental health impact of 9/11 attacks among the individuals living close to the disaster area and compared them to the individuals living farther from the disaster area. New York (NY) state and Washington DC were selected as the disaster areas and Illinois (IL) was selected to study individuals living farther from the disaster area. The study also ...

Text Mining In Radiology Reports, Tianxia Gong, Chew Lim Tan, Tze-Yun Leong, Cheng Kiang Lee, Boon Chuan Pang, C. C. Tchoyoson Lim, Qi Tian, Suisheng Tang, Zhuo Zhang

Research Collection School Of Computing and Information Systems

Medical text mining has gained increasing interest in recent years. Radiology reports contain rich information describing radiologist's observations on the patient's medical conditions in the associated medical images. However as most reports are in free text format, the valuable information contained in those reports cannot be easily accessed and used, unless proper text mining has been applied. In this paper we propose a text mining system to extract and use the information in radiology reports. The system consists of three main modules: a medical finding extractor a report and image retriever and a text-assisted image feature extractor In ...

Evaluations Of The Effectiveness Of A Web-Based Graduate Epidemiology Course, Molly A. Rose, Anthony J. Frisby, Michael D. Hamlin, Susan S. Jones

Anthony J Frisby, PhD

An online epidemiology course was developed, implemented, and evaluated for graduate nursing students through the collaborative efforts of nursing faculty and information, education, and instructional design staff of the library at a health sciences university. This epidemiology course is a core curriculum course for graduate nursing students. The course was piloted with 14 students (one student in Romania); the initial online offering ran concurrently with a traditional classroom section. Extensive evaluation data were collected and analyzed to compare the effectiveness of the classroom and distance-learning formats. Areas of evaluation included objective measures, such as midterm and final examination scores and ...

Health Policy Newsletter Goes On-Line!, Anthony J. Frisby

Anthony J Frisby, PhD

No abstract available.

Outcomes In Culture Positive And Culture Negative Ascitic Fluid Infection In Patients With Viral Cirrhosis: Cohort Study, Lubna Kamani, Khalid Mumtaz, Umair S. Ahmed, Ailia W. Ali, Wasim Jafri

Department of Medicine

Background: Ascitic fluid infection (AFI) in cirrhotic Patients has a high morbidity and mortality. It has two variants namely, spontaneous bacterial peritonitis (SBP) and culture negative neutrocytic ascites (CNNA). The aim of this study was to determine the outcome in cirrhotic Patients with culture positive (SBP) and culture negative neutrocytic ascites. Methods: We analyzed 675 consecutive hepatitis B and/or C related cirrhosis Patients with ascites admitted in our hospital from November 2005 to December 2007. Of these, 187 Patients had AFI, clinical and laboratory parameters of these Patients including causes of cirrhosis, Child Turcotte Pugh (CTP) score were recorded ...

Chromatin Remodeling And Transcriptional Memory: A Dissertation, Sharmistha Kundu

Morningside Graduate School of Biomedical Sciences Dissertations and Theses

Transcriptional regulation of gene expression is critical for all unicellular and multicellular organisms. The ability to selectively induce or repress expression of only a few genes from the entire genome gives cells the ability to respond to changing environmental conditions, grow and proliferate. Multicellular organisms begin life as a single totipotent cell, which undergoes many cell divisions during embryonic and later postnatal development. During this process, the dividing cells of the embryo progressively lose their pluripotency and adopt restricted cell fates. Cell fate restriction leads different cell types to gain unique transcriptional profiles. This transcriptional profile or gene expression pattern ...