Medicine and Health Sciences Commons^™

Gastrointestinal Bleeding Among Oral Anticoagulant Users: A Comprehensive 7-Year Retrospective Review Using Türkiye’S National Health Data System, Nuray Yi̇lmaz Çakmak, Nai̇m Ata, Serdar Can Güven, Emi̇n Gemci̇oğlu, Murat Çağlayan, Mustafa Mahi̇r Ülgü, Şuayi̇p Bi̇ri̇nci̇

Turkish Journal of Medical Sciences

BackgroundThe comparative risk of gastrointestinal bleeding (GIB) among users of direct-acting oral anticoagulants (DOACs) versus vitamin K antagonists (VKAs) is a topic of ongoing debate. This study leverages a comprehensive national health database to evaluate the incidence of GIB, associated risk factors, and post-bleeding management strategies among anticoagulated patients.MethodsUtilizing the Turkish Ministry of Health's e-Nabız system, we conducted a retrospective analysis of patients treated with DOACs and warfarin from January 2017 to July 2023. GIB events were identified using ICD codes, and comorbidities, prior medication use, interventions, and mortality rates were analyzed. Drug survival and switch patterns post-GIB were also …

Association Of Gait Speed And Handgrip Strength With Falls In Older Adults: The Role Of Cognition, Nesli̇han Kayahan Satiş, Sultan Keski̇n Demi̇rcan, Mehmet İlki̇n Naharci

Turkish Journal of Medical Sciences

Background/aim: Fall risk assessment is crucial for older adults because falls are associated with morbidity and mortality. This study investigated the relationship of gait speed (GS) and handgrip strength (HGS) with falls and assessed whether cognition mediates this causality.Materials and methods: The study was conducted in a tertiary referral geriatric outpatient clinic. The physical performance of participants was evaluated by GS and HGS. All falls the previous year were noted and factors associated with falls were analyzed using multivariate regression analysis.Results: A total of 1,018 older adults, with a mean age of 78.8 years (±7.2), of whom 64.2% were female, …

Braf Inhibitor Candidate Molecule Usnic Acid Might Use Both Intrinsic And Extrinsic Pathways Of Apoptosis, Burcu Peli̇n Buyuk, Demet Cansaran Duman, Turker Duman

Turkish Journal of Medical Sciences

Background/aim: Melanoma is one of the most aggressive cancers and treatment methods commonly used for patients with skin cancer include checkpoint and BRAF/MEK inhibitors, traditional chemotherapy drugs, radiation and adjuvant treatment methods. Due to the resistance and toxic effects that the patient develops against the drugs, an effective treatment method has not been developed for melanoma yet. Materials and methods: In this study we evaluated the anti-cancer effect of usnic acid (UA) on A-375 melanoma cells and human epidermal melanocytes by xCELLigence real-time cell analysis system. To determine through which cell death pathway UA exerts its anti-proliferative effect, its apoptotic …

Are Serum Thrombomodulin And Interleukin-8 Levels Associated With Disease Severity And Mortality In Critically Ill Children With Respiratory Failure?, Di̇lan Akgün Ünlü, Hazal Ceren Tuğrul, Selen Ceren Çakmak, Gürkan Atay, Seher Erdoğan

Turkish Journal of Medical Sciences

Background/aim: Thrombomodulin (TM) is found on endothelial cell surfaces and increases in response to endothelial injury of different organs. Interleukin (IL)-8 regulates pulmonary inflammation. TM and IL-8 are candidate biological markers of acute respiratory distress syndrome (ARDS). The aim of the present study was to compare TM and IL-8 levels in pediatric patients with and without ARDS who received respiratory support and to determine their relationships with prognosis.Materials and methods: This was a prospective observational study of 55 patients who received respiratory support in the pediatric intensive care unit. Eighteen patients without active infection were defined as the control group. …

A Word From The Writing Team (January 2024), Pam Walter, Mfa, Liz Declan, Ma, Mfa

A Word From the Writing Team (Newsletter)

This issue includes:

• Virtual Writing Retreats Return in February
• The OPWPC Canvas Page Offers Helpful Tools
• Academic Commons Will Host a Presentation on Refugee Health in Philadelphia
• Publication Spotlight
• The OPWPC Helps with Scholarly Communication and Publication
• Scott Memorial Library Renovations Continue
• Wiley Open Access Fees Waived for Jefferson Authors

Expression Of Growth Differentiation Factor 15 (Gdf-15) In Placental Tissue Of Full- Term Pregnant Women With Hypertensive Disorders In A Western Australian Population, Elsa H. L. Chew

Theses: Doctorates and Masters

Women who experience hypertensive pregnancy disorders (HPDs) during pregnancy, mainly pre-eclampsia (PE), are four times more likely to develop hypertension after pregnancy and therefore have an increased risk of developing cardiovascular diseases (CVD) in the future. Pregnancy involves a high level of cardiovascular stress and the development of some complications. This has the potential to increase a woman’s susceptibility to vascular or metabolic disease risk in the future. In this research, pre-eclampsia (PE) and pregnancyinduced hypertension (PIH) were representatives of HPDs and were analysed together for the expression of Growth Differentiation Factor-15 (GDF-15) relative to their healthy agematched controls.

GDF-15 …

Understanding Mental Wellbeing Of Family Day Care Educators In Australia: A Mixed Methods Study, Theresa Rayfield

Theses: Doctorates and Masters

Family Day Care (FDC) is an essential service within the Australian early childhood education and care sector. FDC educators support Australian families who require convenience, flexibility, and versatility in the education and care of their children. FDC educators’ mental wellbeing (MWB) is vital to ensure optimal education and care is provided, however this is often overlooked by educators. This research aimed to gauge Australian FDC educators’ MWB, identify factors positively or negatively affecting MWB and strategies employed to maintain and support MWB.

Primarily, a cross-sectional quantitative questionnaire measuring MWB and ten predictor variables determining relationship with food, food insecurity, alcohol …

Novel Methods For Assessing Pulmonary And Cardio-Vascular Limitations To Aerobic Performance In Older And Younger Populations, Toni Haddad

Theses: Doctorates and Masters

Around the world, life expectancy is increasing, the ageing population is growing, and maintaining quality of life at an older age currently represents a major global challenge. While ‘successful ageing’ relies on a variety of factors, aerobic performance and exercise capacity are key determinants and attenuating their decline is of the utmost importance. The decrease in maximal oxygen consumption is often considered as a major determinant explaining the age[1]related decline in aerobic performance. Yet, multiple physiological systems are impaired with ageing and their contribution to aerobic limitation in older individuals is unclear. Understanding how the limitations to aerobic performance may …

Exploring Treatment Burden In People With Type 2 Diabetes Mellitus (T2dm) In Primary Care Settings, Kai Lin

Theses: Doctorates and Masters

Introduction

Treatment burden is the perceived workload of care by individuals. The treatment burden experienced by individuals with Type 2 Diabetes Mellitus (T2DM) is a major obstacle to achieving effective healthcare outcomes. The aim of this research is to facilitate better management of treatment burden in people with T2DM in primary care settings.

Methods

A systematic review, encompassing narrative analysis was used to characterise the treatment burden of T2DM and critical appraisal was used to identify the appropriate patient-reported outcome measures (PROMs) for measuring this burden. The selected instruments were employed with subsequent questionnaires, followed by patient focus groups. A …

Western Australian Mothers' Experiences Of Breastfeeding Support In Hospital After Birth: A Mixed Methods Study, Justine Van Der Watt

Theses: Doctorates and Masters

Background: The benefits of breastfeeding are well established for infants, mothers and the community, with the World Health Organisation recommending that infants be exclusively breastfed up to six months of age with an achievable goal of 70% globally. Yet in Australia only 15-37% may be reaching that goal. There have also been reported benefits and desires for mothers to be supported with their breastfeeding in order to increase and prolong breastfeeding duration and exclusivity, especially early after birth. However, there is limited research or literature exploring what experiences mothers are having with breastfeeding support, especially during their hospital admissions in …

Preparing For End Of Life In A New Country: A Grounded Theory Study On African Migrants Living In Australia, Gertrude Gondwe Phiri

Theses: Doctorates and Masters

African migration to Australia has grown in the past 20 to 25 years with many migrants staying permanently. This has led to migrants dying away from their birthplaces where family is responsible for end-of-life care planning for the individual. Although migrating to Australia is considered a great achievement, many migrants also experienced challenges. Previous studies have explored the barriers faced by migrants in relation to end-of-life care but have not addressed the cause of those challenges. This constructivist grounded theory study examines how migrants from three African countries, Malawi, Zambia, and Zimbabwe (MZZ) prepare for end-of-life in Australia. The study …

Prevalence Trends Of Foodborne Pathogens, Bacillus Cereus, Non Stec Escherichia Coli And Staphylococcus Aureus In Ready-To-Eat Foods Sourced From Restaurants, Cafés, Catering And Takeaway Food Premises, Nicole Foxcroft

Theses: Doctorates and Masters

The foodborne pathogens of Bacillus cereus (B. cereus), non STEC Escherichia coli (non STEC E. coli) and Staphylococcus aureus (S. aureus) are currently non-notifiable in Australia unless attributed to a food poisoning outbreak. Due to the lack of data around individual cases and isolations in foods, any changes in prevalence may go undetected. The aim of the study was to determine any changes in prevalence of B. cereus, non STEC E. coli and S. aureus in ready-to-eat foods (RTE) sampled from Western Australian restaurants, cafés, catering facilities, and takeaway food premises during the period July 2009 to June 2022. The …

Best Practice Recommendations For Coaching Gymnasts To Avoid Burnout And Reframe Performance Anxiety, Clare A. Mccall

Theses: Doctorates and Masters

Gymnastics is deemed a psychologically demanding sport, with associated risk factors of burnout and performance anxiety. To date, relatively little research has explored the specific goal and perfectionistic processes of gymnasts, despite these risks. This body of work identified the specific goal-related constructs and perfectionistic orientation of young athletes and examined how these associated with burnout and performance anxiety. It comprised of two studies with a mixed methods design. The first study aimed to systematically review literature investigating how goal-related constructs and perfectionism associate with burnout and performance anxiety in young athletes. This review focused on summer and winter Olympic …

Associations Of Vegetable And Potato Intakes With Markers Of Type 2 Diabetes Risk In The Ausdiab Cohort: Supplemental Information, Pratik Pokharel, Lauren C. Blekkenhorst, Catherine P. Bondonno, Kevin Murray, Simone Radavelli-Bagatini, Dianna J. Magliano, Robin M. Daly, Jonathan E. Shaw, Joshua R. Lewis, Jonathan M. Hodgson, Nicola P. Bondonno

Research outputs 2022 to 2026

No abstract provided.

First-Line Chemoimmunotherapy And Immunotherapy In Patients With Non-Small Cell Lung Cancer And Brain Metastases: A Registry Study, Lauren J. Brown, Victor Khou, Chris Brown, Marliese Alexander, Dasantha Jayamanne, Joe Wei, Lauren Gray, Wei Chan, Samuel Smith, Susan Harden, Antony Mersiades, Lydia Warburton, Malinda Itchins, Jenny H. Lee, Nick Pavlakis, Stephen J. Clarke, Michael Boyer, Adnan Nagrial, Eric Hau, Ines Pires Da Silva, Steven Kao, Benjamin Y. Kong

Research outputs 2022 to 2026

Introduction: Brain metastases commonly occur in patients with non-small cell lung cancer (NSCLC). Standard first-line treatment for NSCLC, without an EGFR, ALK or ROS1 mutation, is either chemoimmunotherapy or anti-PD-1 monotherapy. Traditionally, patients with symptomatic or untreated brain metastases were excluded from the pivotal clinical trials that established first-line treatment recommendations. The intracranial effectiveness of these treatment protocols has only recently been elucidated in small-scale prospective trials. Methods: Patients with NSCLC and brain metastases, treated with first-line chemoimmunotherapy or anti-PD-1 monotherapy were selected from the Australian Registry and biObank of thoracic cancers (AURORA) clinical database covering seven institutions. The primary …

How Have We Measured Trial Outcomes Of Asthma Attack Treatment? A Systematic Review, Imran Howell, Aleksandra Howell, Sanjay Ramakrishnan, Mona Bafadhel, Ian Pavord

Research outputs 2022 to 2026

Background Asthma attacks are a common problem for people with asthma and are responsible for significant healthcare costs. There is interest in a precision medicine approach to treatment. However, the choice of trial outcome measures for asthma attack treatment is hampered by the absence of a consensus on suitability. We carried out a systematic review to understand the characteristics of outcome measures used in randomised controlled trials of asthma attack treatment. Have randomised controlled trials of asthma attack treatment measured outcomes that are useful to patients and healthcare providers? Methods The protocol was registered on PROSPERO (CRD42022311479). We searched for …

The Experiences Of Older Immigrants Living With Dementia In Australia: A Multi-Method Secondary Analysis, Pelden Chejor

Theses: Doctorates and Masters

The ageing immigrant population and rising dementia cases underscores the need for culturally appropriate dementia care services. However, accessing dementia care services can be challenging for immigrants due to cultural and linguistical differences including their health beliefs. Understanding the experiences and concerns of older immigrants living with dementia is imperative for the planning and delivery of culturally and linguistically appropriate care. The aim of this thesis was to explore and describe the experiences of older immigrants living with dementia, as well as to describe and compare (against non-immigrants living with dementia) the characteristics (neuropsychiatric symptoms and pain characteristics) of older …

The Lumbar Stabilization Exercise And Balance Training In Low-Grade Degenerative Lumbar Spondylolisthesis - A Prospective, Clinical Trial, Yun-Chung Lin, Mei-Yun Liaw, Tsung-Hsun Yang, Ya-Ping Pong, Yan-Yuh Lee, Chien-Wei Chen, Song-Chung Chen, Yu-Chi Huang

Rehabilitation Practice and Science

BACKGROUND: Patients with degenerative lumbar spondylolisthesis (DLS) may have low back pain (LBP), radicular pain and spinal instability. Current programs emphasize intervention of spinal stabilization exercise. However, no prospective, randomized studies have elucidated standardized treatment for DLS.

OBJECTIVE: To examine the effect of spinal stabilization exercise and Biodex balance system (BBS) training in patients with DLS.

METHODS: It was a prospective, clinical trial. Participants were allocated into three groups: (1) DLS-balance group treated with balance training (DLSB), (2) DLS non-balance training group (DLSNB), and (3) lumbar spondylosis without spondylolisthesis (SC). ALL patients underwent a rehabilitation program with lumbar stabilization exercises. …

A Case Report: Regenerative And Robotic Rehabilitation In A Patient With Chronic Hypoxic-Ischemic Encephalopathy, Chieh Chen, Sun-Hui Tseng

Rehabilitation Practice and Science

Hypoxic-ischemic encephalopathy (HIE) occurs when the brain is deprived of sufficient oxygen or blood flow, resulting in brain dysfunction. According to the relevant literature, no curative therapies are currently available for HIE-related lifelong disabilities. Regenerative rehabilitation employs regenerative technologies and cell therapy combined with conventional therapeutic exercises to restore normal function. This study used robotic-assisted gait training with the Lokomat and two infusions of human umbilical cord mesenchymal stem cells (hUC-MSCs) to treat an adolescent with chronic HIE. At the seven-month follow-up assessment, we determined that the patient’s motor function had improved based on the Gross Motor Function Measure-88 (GMFM-88) …

Ultrasonography Contributing To The Diagnosis And Treatment Of Ischial Bursitis–A Case Report, Fan Mei, Yu-Shan Fu, Lin-Fen Hsieh

Rehabilitation Practice and Science

A 59-year-old woman presented with persistent right buttock pain, exacerbated by prolonged sitting due to her occupation in watch repair. Physical examination revealed tenderness at the right ischial tuberosity and frictional melanosis. Ultrasound identified an anechoic, compressible mass in the region, a notable finding given the rarity of such detailed imaging in ischial bursitis cases. We performed ultrasound-guided aspiration and corticosteroid injection, resulting in significant symptom relief. The patient also received recommendations for physical therapy and lifestyle adjustments. Follow-up confirmed resolution of fluid and pain. This case highlights the important role of ultrasound in diagnosing and managing ischial bursitis.

Atlantoaxial Rotatory Fixation Due To Congenital Strabismus: A Case Report, Chih-Ting Chen, Chia-Ling Lee

Rehabilitation Practice and Science

Background Atlantoaxial Rotatory Fixation (AARF) is a relatively rare condition, most diagnosed in the children, with common etiologies including minor trauma and upper respiratory infections. However, cases of AARF resulting from congenital strabismus are yet to be reported. Objective We aimed to underscore the uncommon association between AARF and congenital strabismus and to evaluate the effectiveness of halter traction. Method In this case report, we present an 11-year-old male patient with a history of congenital strabismus, which led to the development of AARF. Results The patient was initially observed to have torticollis and strabismus at the age of 4 months. …

Comparing Findings Of Hemophilia Joint Health Score And Hemophilia Early Arthropathy Detection With Ultrasound Assessments In Taiwanese Patients With Severe Hemophilia, Yen-Ling Huang, Hong-Yi Lin, Te-Fu Weng, Sheng-Wei Zeng, Yueh-Han Ku, Yu-Hui Huang

Rehabilitation Practice and Science

Purpose: This study aimed to evaluate the correlation between Hemophilia Joint Health Score 2.1 (HJHS 2.1) and Hemophilia Early Arthropathy Detection with Ultrasound (HEAD-US) in Taiwanese patients with severe hemophilia and identify specific items within HJHS to predict early ultrasonic changes in hemophilic arthropathy (HA).

Methods: Thirty-six patients with a total of 210 joints were evaluated. We used Spearman's rank correlation coefficient to analyze the correlation between these two scales. The sensitivity, specificity, and accuracy of each HJHS item were also calculated to predict early HA.

Results:These two scales showed very strong correlation in the total scores …

Annotated Bibliography On The Mechanism Starting And Sustaining Atherosclerosis, Dat H. Pham, Thach Nguyen, Hao Thuy Nguyen, Marco Zuin, Duc Khiem Ngo, Hadrian Tran, Nhat H. Pham, Thinh T. Nguyen, Chau Dang, Pham Tv Le

School of Medicine Publications

Background: In the past 30 years, there has been a significant rise in coronary artery disease (CAD) and atherosclerosis, primarily attributed to dietary changes toward cholesterol-rich fast foods. Traditional research methodologies focusing on molecular biology have been insufficient in fully understanding the initiation mechanisms of these conditions. This paper reviews the literature and defines the knowledge gap for the need for a new dynamic coronary angiographic technique.

Methods: Our approach involved a comprehensive review of fluid mechanics literature to identify gaps in current CAD research. This included analyzing major works from standard physiology textbooks, fluid mechanics reviews, and bioengineering …

Preliminary Results Of A Study Using Dynamic Angiography In Predicting Progression Or Regression Of Moderate Severity Lesions, Thach Nguyen, Marco Zuin, Pham Tv Le, Vinh Sieu Lam, Hien Q. Nguyen, Hung V. Dang, Huyen K. Huynh, Duc Khiem Ngo, Thinh T. Nguyen, Imran Mihas

School of Medicine Publications

Background: Many patients with stable angina (SA) having moderate 50% lesions could deteriorate or stay stable for a long time. No present techniques nor test could accurately predict the progression to acute coronary syndrome (ACS) or stabilization of these moderate lesions. Based on the fluid dynamic methodology research, could turbulent flow further damage the plaque and rupture its cap? In contrast, could laminar flow delay the progression of the plaque and keep patients stable for a long period of time?

Methods: Patients with stable angina (SA) were admitted to the intermediate care unit and underwent coronary angiography. Patients were selected …

Peripartum Cardiomyopathy; Understanding And Improving Outcomes-A Systematic Review, Shakirat Ganiyu, Taiwo Akeem Lawal, Sarah Petrie

School of Medicine Publications

Background: Peripartum cardiomyopathy (PPCM) presents a significant global health challenge, contributing substantially to maternal morbidity and mortality worldwide. Despite ongoing research efforts, the multifaceted nature of PPCM, encompassing genetic, environmental, and clinical factors, necessitates a comprehensive understanding to improve patient outcomes effectively.

Aims: This systematic review aims to synthesise current knowledge on PPCM aetiology, risk factors, diagnosis, therapeutic interventions, and prognostic indicators, highlighting recent advancements and potential avenues for future research and clinical management. By addressing key aspects such as genetic predispositions, environmental influences, diagnostic strategies, therapeutic modalities, and global disparities, this review seeks to provide insights that can inform …

Dual Suppression Of Glossina Pallidipes Using Entomopathogenic Fungal-Based Biopesticides And Sterile Insect Technique, Fidelis L.O. Ombura, Adly M.M. Abd-Alla, Komivi S. Akutse, Steven Runo, Paul O. Mireji, Rosemary Bateta, Joseck E. Otiwi, Inusa J. Ajene, Fathiya M. Khamis

All Peer-Reviewed Publications

Tsetse flies and trypanosomosis significantly impact bovine production and human health in sub-Saharan Africa, exacerbating underdevelopment, malnutrition, and poverty. Despite various control strategies, long-term success has been limited. This study evaluates the combined use of entomopathogenic fungi (EPF) and the sterile insect technique (SIT) to combat tsetse flies. Eleven EPF isolates were tested against teneral males of Glossina pallidipes, focusing on mortality rates, radial growth, and impacts on fly fitness. Temperature effects on conidial growth, sporulation, and spore yield of SIT-compatible/tolerant strains were also assessed. The fungal isolates significantly influenced mortality rates in both unirradiated and irradiated (SIT-treated) males (p <  0.0001). Metarhizium anisopliae strains ICIPE 20, ICIPE 32, ICIPE 41, ICIPE 62, ICIPE 78, and Beauveria bassiana ICIPE 603 showed higher SIT compatibility/tolerance with LT50 values of 11–30 days, compared to other more virulent isolates with LT50 values of 4–9 days. Temperature significantly affected the radial growth of SIT-compatible EPF strains (p <  0.0001), with M. anisopliae ICIPE 78 exhibiting the fastest conidia growth at 25°C. Spore yield varied significantly across temperatures (15–40°C), and the thermal range for conidia germination of SIT-compatible strains was 8.1–45.4°C, with an optimal range of 26.7–31.1°C. Moreover, infected unirradiated females and irradiated males (donors) successfully transmitted conidia to untreated flies (receivers) without significant differences in survival rates (p = 0.6438) and no observed sex dimorphism. Our findings highlight the potential of combining EPF and SIT as a novel dual approach that could effectively and synergistically suppress tsetse fly populations.

Tissue-Specific Localization Of Tick-Borne Pathogens In Ticks Collected From Camels In Kenya: Insights Into Vector Competence, Rua Khogali, Armanda Bastos, Joel L. Bargul, Dennis Getange, James Kabii, Daniel Masiga, Jandouwe Villinger

All Peer-Reviewed Publications

Background: Tick-borne pathogen (TBP) surveillance studies often use whole-tick homogenates when inferring tick-pathogen associations. However, localized TBP infections within tick tissues (saliva, hemolymph, salivary glands, and midgut) can inform pathogen transmission mechanisms and are key to disentangling pathogen detection from vector competence. Methods: We screened 278 camel blood samples and 504 tick tissue samples derived from 126 camel ticks sampled in two Kenyan counties (Laikipia and Marsabit) for Anaplasma, Ehrlichia, Coxiella, Rickettsia, Theileria, and Babesia by PCR-HRM analysis. Results: Candidatus Anaplasma camelii infections were common in camels (91%), but absent in all samples from Rhipicephalus pulchellus, Amblyomma gemma, Hyalomma dromedarii, …

Technoference In Parenting And Impacts On Parent–Child Relationships And Child Development, Brandon T. Mcdaniel Phd, Lisa Linder, Mariek M.P. Vanden Abeele, Alison K. Ventura, Sarah M. Coyne, Rachel Barr

Health Services and Informatics Research

“Technoference” is a term that describes how parent media use (e.g., phone use) can interfere with parent–child relationships and interactions. Research has shown technoference effects on parents and children ranging in age from infancy to adolescence, such as decreased parent responsiveness and adverse child behavioral outcomes. However, potential benefits of parent media use have also been identified, such as media use to cope with stress, stay connected, increase breastfeeding perseverance, and seek parenting information. Technoference has only been researched for about a decade, and there are large research gaps. We propose a research agenda to parse out long-term or cumulative …

Daily Smartphone Use Predicts Parent Depressive Symptoms, But Parents' Perceptions Of Responsiveness To Their Child Moderate This Effect., Brandon T. Mcdaniel Phd, Sabrina Uva, Jessica Pater, Victor P. Cornet Ms, Michelle Drouin Phd, Jenny Radesky

Health Services and Informatics Research

INTRODUCTION: Smartphone use during caregiving has become increasingly common, especially around infants and very young children, and this use around young children has been linked with lower quality and quantity of parent-child interaction, with potential implications for child behavior, and parent-child attachment. To understand drivers and consequences of parent phone use, we were interested in the daily associations between parent phone use and depressed mood, as well as the potential for parent perceptions of their responsiveness toward their infant to alter the association between parent phone use and mood.

METHODS: In the present study, we explored associations between day-to-day changes …

Heavy Users, Mobile Gamers, And Social Networkers: Patterns Of Objective Smartphone Use In Parents Of Infants And Associations With Parent Depression, Sleep, Parenting, And Problematic Phone Use., Brandon T. Mcdaniel Phd, Jenny Radesky, Jessica Pater, Adam M Galovan, Annalise Harrison, Victor P. Cornet Ms, Lauren Reining, Alexandria Schaller, Michelle Drouin

Health Services and Informatics Research

Smartphone use during parenting is common, which may lead to distraction (also known as technoference). However, it is likely that some phone activities are less disruptive to parents and children. In this study, we explored smartphone use (via passive sensing across 8 days) within 264 parents of infants, measuring parents' application use on their phone (e.g., messaging, social media, mobile gaming, video chat) and phone use across contexts (e.g., during feeding and at bedtime). We utilized latent profile analysis to identify profiles of users, revealing five user types: