Medicine and Health Sciences Commons^™

Conflict With Patient: Patient Frustration With Wait Time, Saleh Al-Juburi, Alexa Kalaj, Amrutha Kotlure, Hannah Lee, Juwan Taylor, Salvatore Serra, Mariam Raheem

Patient Education Projects

No abstract provided.

Conflict With Peer: Multiple Late Arrivals, Anastasia Goldbaum, Austin Kim, Cole Sabinash, Gabrielle Cowen, Kassim Salami, Simran Brar, Sahalia Rashid

Patient Education Projects

No abstract provided.

Conflict With Peer: Unexcused Co-Absence Of Resident, Adam Chaban, Ajay Pradhan, Aminah Fayyaz, Cyrus Amirfazli, Karina Haleblian, Nina Brahmbhatt, Amanah Fatima

Patient Education Projects

No abstract provided.

Conflict With Peer: Team Workload, Anisha Patel, Annelise Gordon, Jonathan Toma, Maximilian Wehner, Rohit Goru, Amanah Fatima

Patient Education Projects

No abstract provided.

Conflict With Peer: Poor Peer Participation, Alexa Bernard, Elli Johnson, Jackson Ferris, Jose Lopez, Susan Hartzell, Theodore Schiff, Amanah Fatima

Patient Education Projects

No abstract provided.

Conflict With Peer: Struggling Colleague, Andrew Lemmen, Daniel Saxon, Devun Birk, Shrila Rajendran, Timothy Li, Ayman Salem

Patient Education Projects

No abstract provided.

Conflict With Peer: Peer’S Lack Of Preparedness, Jacob Waitzman, Isabella Anton, Parnia Behinaein, Patrick Kollman, Samy Shelbaya, Yage Pi, Mariam Raheem

Patient Education Projects

No abstract provided.

Conflict With Peer: Treatment Plan Disagreement, Dhiraj Tadikamalla, Lara Rostomian, Meet Patel, Neil Garg, Sara Naessig, Sohini Pandit, Mariam Raheem

Patient Education Projects

No abstract provided.

Group Reflection: White Coat And Physician-Patient Relationship, Emily Smith, Joseph Mccormick, Lukas Biel, Melissa Elmali, Mura Abdul-Nabi, Nitya Deshpande, Sahalia Rashid

Patient Education Projects

No abstract provided.

Group Reflection: Confidence And Functioning In A Medical Team, Anisha Patel, Annelise Gordon, Jonathan Toma, Maximilian Wehner, Rohit Goru, Amanah Fatima

Patient Education Projects

No abstract provided.

Group Reflection: White Coat As A Symbol Of Trust, Ahmed Jafri, Brianna Regan, Maya Kohavi, Tareq Hanna, Zarin Kothari, Amanah Fatima, Fadi Kathawa

Patient Education Projects

No abstract provided.

Group Reflection: Different Interpretations The White Coat Has On Patients, Arainya Durham, Jacob Hall, James Soetedjo, Khush Hussain, Samantha Markowitz, Shruthi Ilango, Amanah Fatima, Fadi Kathawa

Patient Education Projects

No abstract provided.

Group Reflection: White Coat As A Symbol Of Healing, Constance Cleveland, Deepa Raghavan, Dipra Debnath, Jay Maixner, Ranya Krayem, Vikash Mehan, Zane Mustafa, Ayman Salem

Patient Education Projects

No abstract provided.

Group Reflection: Being Cognizant Of The Dichotomy The White Coat Holds, Demetrius Moncrease, Parshva Salvi, Basel Mhaimeed, Fadumo Yusuf, Marissa Yaldo, Sneha Bhargava, Kenan Abou Chaer, Astha Saini

Patient Education Projects

No abstract provided.

Group Reflection: White Coat As A Sense Of Belonging, Era Cobani, Angelica Cabatu, Carly Abrahams, Curtis Mack, Michal Ruprecht, Nicholas Apostolakis, Mariam Raheem

Patient Education Projects

No abstract provided.

Conflict With Peer: Late Group Mate, Constance Cleveland, Deepa Raghavan, Dipra Debnath, Jay Maixner, Ranya Krayem, Vikash Mehan, Zane Mustafa, Ayman Salem

Patient Education Projects

No abstract provided.

Meta-Narrative Synthesis: The Effectiveness Of Diagnosing And Treating Melanoma With Micrographically Oriented Histograph Surgery Mohs Technique, Gabriella Casas Ms, Nida Mubeen Ms, Nicole Rivera Ms, Tan Thien Tang Mr., Mark A. Bailey Mr, Mary Coolbaugh-Murphy, Denise M. Juroske Short Mrs

Research Methods Poster Session 2024

This meta-narrative synthesis highlights the effectiveness of diagnosing and treating melanoma with Micrographically Oriented Histography Surgery (MOHS) technique. Initiating the questions: What techniques does MOHS surgery involve when diagnosing and treating non-metastasized Melanoma? How will it provide positive outcomes for the patient? The significance of using MOHS excision technique and diagnosis of localized facial melanoma compared to traditional cancer excision techniques is designed to remove affected tissue while preserving anatomical facial structure in an aesthetic fashion. Providing an overview of the technique’s diagnostic professional capabilities as well as its strengths, limitations, improvement for upcoming studies, and potential prognosis. Melanoma, a …

Efficacy And Safety Of Once-Weekly Insulin Regimes On Glycemic Control For Type 2 Diabetes: A Systematic Review And Network Meta-Analysis, Peng Wang, Yu Zhang, Wenhao Xu, Liyuan Peng, Ping Xu, Weelic Chong, Yang Hai, Lu Jia, Fang Fang

Student Papers, Posters & Projects

Background

Randomized controlled trials have found that once-weekly insulin resulted in greater glycemic control compared to once-daily insulin in patients with type 2 diabetes. However, no direct comparisons have been made between different types of once-weekly insulin thus far. This systematic review and network meta-analysis aimed to evaluate the effect of the two most advanced once-weekly insulin analogues, namely insulin icodec and insulin Fc, in patients with type 2 diabetes.

Methods

We conducted a thorough search in the databases PubMed, Embase, and the Cochrane Central Register of Controlled Trials. The search included articles published from the beginning to October 10, …

20240103_A Warm Welcome, Laura J. Hall

HSLIC Blog Post

No abstract provided.

Targeting Dna Repair And Survival Signaling In Diffuse Intrinsic Pontine Gliomas To Prevent Tumor Recurrence, Monika Sharma, Ivana Barravecchia, Robert Teis, Jeanette Cruz, Rachel Mumby, Elizabeth K Ziemke, Carlos E Espinoza, Varunkumar Krishnamoorthy, Brian Magnuson, Mats Ljungman, Carl Koschmann, Joya Chandra, Christopher E Whitehead, Judith S Sebolt-Leopold, Stefanie Galban

Faculty, Staff and Student Publications

Therapeutic resistance remains a major obstacle to successful clinical management of diffuse intrinsic pontine glioma (DIPG), a high-grade pediatric tumor of the brain stem. In nearly all patients, available therapies fail to prevent progression. Innovative combinatorial therapies that penetrate the blood-brain barrier and lead to long-term control of tumor growth are desperately needed. We identified mechanisms of resistance to radiotherapy, the standard of care for DIPG. On the basis of these findings, we rationally designed a brain-penetrant small molecule, MTX-241F, that is a highly selective inhibitor of EGFR and PI3 kinase family members, including the DNA repair protein DNA-PK. Preliminary …

Enrichment Of Polycyclic Aromatic Hydrocarbon Metabolizing Microorganisms On The Oral Mucosa Of Tobacco Users, James V. Defrancesco, Lin Tao, M Paul Chiarelli, Sylvia Pavlova, Antonia Kolokythas, Joel Schwartz, Benjamin Salameh, Stefan J. Green, Guy Adami

Chemistry: Faculty Publications and Other Works

Certain soil microbes resist and metabolize polycyclic aromatic hydrocarbons (PAHs). The same is true for a subset of skin microbes. In the human mouth, oral microbes have the potential to oxidize tobacco PAHs, thereby increasing these chemicals' ability to cause cancer of adjacent epithelium. We hypothesized that we could identify, in smokers, the oral mucosal microbes that can metabolize PAH. We isolated bacteria and fungi that survived long-term in minimal media with PAHs as the sole carbon source, under aerobic conditions, from the oral mucosa in 17 of 26 smokers and two of 14 nonsmokers. Of bacteria genera that survived …

Age- And Sex-Specific Normative Values For Muscle Mass Parameters In 18,625 Brazilian Adults., Hélio José Coelho-Júnior, Fillipi Lopes Marques, Caio Victor Sousa, Emanuele Marzetti, Samuel Da Silva Aguiar

Health and Human Sciences Faculty Works

Background: The present study aimed to provide age- and sex-specific normative values for muscle mass parameters in Brazilian adults.

Methods: Data pertaining to Brazilian adults (18+ years) who attended a nutritional clinical between January 2018 and July 2022 were analyzed. Muscle mass parameters were assessed using a bioimpedance digital scale (InBody 230, GBC BioMed NZ). Assessments were conducted under standard conditions, with participants refraining from physical exercise for 96 h and from eating or drinking (including water) for 8 h before evaluations.

Results: A total of 18,625 Brazilian adults were analyzed. Normative values for absolute and relative (height, m^{2 …}

The Barriers To Adult Play In Graduate Students, Rosalind Nolde, Catherine Salomon, T. Monelli, Sabrina Solis

Occupational Therapy | Graduate Student Research Posters

The purpose of this study is to expand the knowledge of barriers to play for graduate students. The research question asked, what are the barriers to play experienced by graduate students? Play is a complex term that is unique to the individual. Although subjective, existing literature gives suggestions as to what play can mean or feel like to the individual participating. Brown (2009), notes that the definition of play should be experienced rather than defined as it is distinctive to each individual. Van Vleet and Feeney (2015) describe play as being the purpose of amusement, fun or to have energetic, …

The Use Of Cardiac Magnetic Resonance In Hypertrophic Cardiomyopathy Over The Past 10 Years [2013-2023]: A Citespace-Based Bibliometric Analysis, Mengyao Hu, Yu Shen, Yipei Song, Shuhao Li, Pei Yang, Ao Kan, Qiming Fang, Yun Peng, Haibo Ren, Yajing Zhang, Lianggeng Gong

Faculty, Staff and Student Publications

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a common genetic cardiac disorder characterized by the hypertrophy of a segment of the myocardium. Cardiac magnetic resonance (CMR) has been widely used in the assessment of HCM. However, no bibliometric assessment has been conducted on the progress of research in this field. This study thus aimed to examine the current state of research into the application of CMR in HCM and the hotspots and trends that have emerged in this field over the past decade.

METHODS: A systematic search was conducted on the Web of Science regarding CMR in the assessment of HCM. The …

Postoperative Systemic Inflammatory Response Syndrome Predicts Increased Mortality In Patients After Elective Craniotomy, Liyuan Peng, Qi Gan, Yangchun Xiao, Jialing He, Xin Cheng, Peng Wang, Lvlin Chen, Tiangui Li, Yan He, Weelic Chong, Yang Hai, Chao You, Fang Fang, Yu Zhang

Department of Medical Oncology Faculty Papers

Introduction: Patients undergoing craniotomy are at high risk of perioperative morbidity and mortality due to excessive inflammatory responses. The purpose of the present study is to evaluate the prognostic utility of postoperative systemic inflammatory response syndrome (SIRS) in patients undergoing craniotomy.

Methods: We performed a retrospective cohort study of patients who underwent craniotomy between January 2011 and March 2021. SIRS was diagnosed based on two or more criteria (hypo-/hyperthermia, tachypnea, leukopenia/leukocytosis, tachycardia). We used univariate and multivariate analysis for the development of SIRS with postoperative 30-day mortality.

Results: Of 12,887 patients who underwent craniotomy, more than half of the patients …

Emotion Regulation From A Virtue Perspective, Jeong Han Kim, Jina Chun, Jaeyoung Kim, Hyun-Ju Ju, Byung Jin Kim, Jeongwoon Jeong, Dong Hun Lee

School of Rehabilitation Services & Counseling Faculty Publications

Background

The ability to regulate one’s emotional state is an important predictor of several behaviors such as reframing a challenging situation to reduce anger or anxiety, concealing visible signs of sadness or fear, or focusing on reasons to feel happy or calm. This capacity is referred to as emotion regulation. Deficits in this ability can adversely affect one’s adaptive coping, thus are associated with a variety of other psychopathological symptoms, including but not limited to depression, borderline personality disorder, substance use disorders, eating disorders, and somatoform disorders.

Methods

The present study examined emotion regulation in relation to the virtue-based psychosocial …

Biallelic Variants In Rbm42 Cause A Multisystem Disorder With Neurological, Facial, Cardiac, And Musculoskeletal Involvement, Yiyao Chen, Bingxin Yang, Xiaoyu Merlin Zhang, Songchang Chen, Minhui Wang, Liya Hu, Nina Pan, Shuyuan Li, Weihui Shi, Zhenhua Yang, Li Wang, Yajing Tan, Jian Wang, Yanlin Wang, Qinghe Xing, Zhonghua Ma, Jinsong Li, He-Feng Huang, Jinglan Zhang, Chenming Xu

Faculty, Staff and Students Publications

Here, we report a previously unrecognized syndromic neurodevelopmental disorder associated with biallelic loss-of-function variants in the RBM42 gene. The patient is a 2-year-old female with severe central nervous system (CNS) abnormalities, hypotonia, hearing loss, congenital heart defects, and dysmorphic facial features. Familial whole-exome sequencing (WES) reveals that the patient has two compound heterozygous variants, c.304C>T (p.R102*) and c.1312G>A (p.A438T), in the RBM42 gene which encodes an integral component of splicing complex in the RNA-binding motif protein family. The p.A438T variant is in the RRM domain which impairs RBM42 protein stability in vivo. Additionally, p.A438T disrupts the interaction of …

Preclinical Repurposing Of Sitagliptin As A Drug Candidate For Colorectal Cancer By Targeting Cd24/Ctnnb1/Sox4-Centered Signaling Hub, Jing-Wen Shih, Alexander T H Wu, Ntlotlang Mokgautsi, Po-Li Wei, Yan-Jiun Huang

Faculty, Staff and Student Publications

Despite significant advances in treatment modalities, colorectal cancer (CRC) remains a poorly understood and highly lethal malignancy worldwide. Cancer stem cells (CSCs) and the tumor microenvironment (TME) have been shown to play critical roles in initiating and promoting CRC progression, metastasis, and treatment resistance. Therefore, a better understanding of the underlying mechanisms contributing to the generation and maintenance of CSCs is crucial to developing CSC-specific therapeutics and improving the current standard of care for CRC patients. To this end, we used a bioinformatics approach to identify increased CD24/SOX4 expression in CRC samples associated with poor prognosis. We also …

Novel Textbook Outcomes Following Emergency Laparotomy: Delphi Exercise, David N Naumann, Aneel Bhangu, Adam Brooks, Matthew Martin, Bryan A Cotton, Mansoor Khan, Mark J Midwinter, Lyndsay Pearce, Douglas M Bowley, John B Holcomb, Ewen A Griffiths, Beacon Collaborative

Faculty, Staff and Student Publications

Background: Textbook outcomes are composite outcome measures that reflect the ideal overall experience for patients. There are many of these in the elective surgery literature but no textbook outcomes have been proposed for patients following emergency laparotomy. The aim was to achieve international consensus amongst experts and patients for the best Textbook Outcomes for non-trauma and trauma emergency laparotomy.

Methods: A modified Delphi exercise was undertaken with three planned rounds to achieve consensus regarding the best Textbook Outcomes based on the category, number and importance (Likert scale of 1-5) of individual outcome measures. There were separate questions for non-trauma and …

Mastitis And Mammary Abscess Management Audit (Mamma) In The Uk And Ireland, Alona Courtney, Jonathon Clymo, Ruth Parks, Alexander Wilkins, Ruth Brown, Rachel O'Connell, Rajiv Dave, Marianne Dillon, Hiba Fatayer, Rachel Gallimore, Ashu Gandhi, Matthew Gardiner, Victoria Harmer, Lyndsey Hookway, Gareth Irwin, Charlotte Ives, Helen Mathers, Juliette Murray, D Peter O'Leary, Neill Patani, Sophie Paterson, Shelley Potter, Ruth Prichard, Giovanni Satta, T G Teoh, Paul Ziprin, Stuart Mcintosh, Michael R Boland, Daniel Richard Leff, Mamma Research Collaborative

Faculty, Staff and Student Publications

BACKGROUND: The aim of this multicentre prospective audit was to describe the current practice in the management of mastitis and breast abscesses in the UK and Ireland, with a specific focus on rates of surgical intervention.

METHODS: This audit was conducted in two phases from August 2020 to August 2021; a phase 1 practice survey and a phase 2 prospective audit. Primary outcome measurements for phase 2 included patient management pathway characteristics and treatment type (medical/radiological/surgical).

RESULTS: A total of 69 hospitals participated in phase 2 (1312 patients). The key findings were a high overall rate of incision and drainage …