Medicine and Health Sciences Commons^™

A Phase 1 Clinical Trial Combining Car T-Cell Therapy With Autologous Hematopoietic Stem Cells In A Multi-Cultural Patient Population, Bry Reinhardt Ms

School of Public Health Delta Omega Honors Day Poster Sessions

Background: Chimeric Antigen Receptor (CAR) T-Cell therapy is a type of immunotherapy designed to treat relapsed/refractory hematologic malignancies such non-Hodgkin B-Cell Lymphoma, B-Cell Acute Lymphoblastic Leukemia, and Multiple Myeloma. CAR T toxicities such as cytokine release syndrome, immune effector cell-associated neurotoxicity syndrome and post-infusion cytopenias pose major challenges to the regimen. Additionally, CAR T is a complicated and involved therapy. It is critical to explain the risks and benefits to patients, which can be challenging when they are non-native English speakers.

Objectives: The co-primary endpoints of this trial are to determine the feasibility of collecting the target cell dose of …

Assessing Stigma In People Living With Hiv, Kyle Mistretta, John W. Apolzan, Hui-Yi Lin, Connie Arnold, Jonathan R. Schroeder, David Welsh, Lauren E. Richey

School of Public Health Delta Omega Honors Day Poster Sessions

Abstract: Stigma and discrimination may result in poorer health literacy, negative health outcomes, and increased morbidity from other chronic diseases in PWH. We created a multidisciplinary team to study stigma, health behaviors, and outcomes in PWH in Louisiana. The team HIV clinics in three cities; New Orleans, Baton Rouge, and Shreveport, forming the Louisiana Translational Collaborative on Health Behaviors [LATCH]. We hypothesized that PWH who report increased stigma would have lower health literacy and more comorbidities.

Methods: PWH aged ≥ 18 were recruited from three HIV clinics during regular appointments. Participants completed standardized surveys that assessed stigma via the HIV …

Eat, Sleep, Console, Claire Hauke, Grace Hauke

Scholars Week

Eat, Sleep, Console is a scale used to assess opioid withdrawing neonates. This scale focuses on infant function and comfort, rather than treating infants based on signs and symptoms of withdrawal alone.

Optimizing Digital Proficiency To Improve Perceived Self-Efficacy In Telehealth Nurses, Serena Young

Doctor of Nursing Practice Projects

The use of telehealth to provide care management services has increased as healthcare continues to evolve. Seven million Americans were predicted to use telehealth in 2020, which increased to over 35 million through the pandemic. These services have been shown to decrease healthcare disparities and promote positive health outcomes. Education and training for nurses providing telehealth services have not kept up with the increased demand. Nurses providing care management telehealth services in a large tertiary health system have low perceived self-efficacy for technology. Leaders in the organization believe this is causing a lack of digital proficiency in their workforce. This …

Implementation Of An Advanced Practice Provider Fellowship To Improve Transition To Practice, Breanne Hosford

Doctor of Nursing Practice Projects

Problem

Retention of advanced practice providers (APPs) is needed for ongoing high quality comprehensive care. Administrators at a large urban pediatric institute in the Midwest identified turnover and retention as an issue for APPs in the first one to two years of service. Even in years when turnover rates were not as high, the greatest number of APPs leaving the institution where those in their first five years of tenure. Without strategies aimed at improving transition to practice, new hire APPs will continue to be unprepared for their new role, therefore endangering job satisfaction, leading to continued turnover, and threatening …

A Patient Centered Quality Improvement Education Program Designed To Improve The Health Of Patients Living With Uncontrolled Hypertension In A Primary Care Setting, Alia Jamison-Dinowitz

Doctor of Nursing Practice Projects

Cardiovascular disease is the leading cause of death in the United States and it negatively contributes to poor health outcomes (Martinez-Garcia et al., 2018). Within the Antelope Valley in Lancaster California, 30.3 % of city residents have a hypertension diagnosis (Los Angeles County of Public Health, 2017). Much like the city at large, hypertension is a critical issue at AV Pediatrics and Family Medicine (AV Peds). This issue is driven by a variety of factors including a lack of understanding about hypertension and medication compliance, and a lack of understanding about healthy lifestyle choices. Providers at AV Peds have seen …

Occupational Impacts Of Seizures, Stephanie Nailon, Karen Park, Kelly Rodenkirch

Spring 2024 Virtual OTD Capstone Symposium

This research looks at the occupational impacts of seizure disorders on the adolescent population. The research study explores how their condition impacts the adolescent and family unit. The research was gathered from multiple perspectives to gain an in-depth understanding to best aid occupational therapists and health care professionals to gain a deeper understanding of areas to address when working with this population.

Development Of A Novel Humanized Anti-Tslp Monoclonal Antibody Hz-1127 With Anti-Allergic Diseases And Cancer Potential., Xiaolei Liu, Jianzhong Han, Qian Wang, Peng Wang, Li Li, Kehe Du, Fengchao Jiang, Pei Zhang, Hongjun Liu, Jian Huang

Cooper Medical School of Rowan University Departmental Research

Thymic stromal lymphopoietin (TSLP) is a member of the IL-2 cytokine family and has been widely recognized as a master regulator of type 2 inflammatory responses at barrier surfaces. Recent studies found dysregulation of the TSLP-TSLP receptor (TSLPR) pathway is associated with the pathogenesis of not only allergic diseases but also a wide variety of cancers including both solid tumors and hematological tumors. Thus, the blockade of TSLP represents an attractive therapeutic strategy for allergic diseases and cancer. In this study, we report the development of a novel humanized anti-TSLP monoclonal antibody (mAb) HZ-1127. Binding affinity, specificity, and ability of …

Voices, Stories And Experiences Of Black Women Phase Ii: Community Engagement Activity Report Informing The Establishment Of A Trenton-Based Maternal & Infant Health Innovation Center, John S. Watson Institute For Urban Policy And Research, Tirzah Spencer, Phd, Mph, Barbara George Johnson

Center for Urban Policy Research

As an extension of our 2022 study Voices, Stories and Experiences of Black Women (Phase 1), the John S. Watson Institute for Urban Policy and Research at Kean University’s Maternal and Child Health Equity Team was asked to share information about the planned Maternal and Infant Health Innovation Center (MIHIC) with Trenton residents as a part of Nurture NJ’s community engagement efforts. The Team implemented the following community engagement activities: Communication: Community engagement through social media outreach and in-person outreach were used as approaches to inform Trenton residents about the MIHIC. Dissemination of Findings: Community cafés were designed to share …

Abortion: Analysis Of The Bioethical And Metaphysical Standpoint, Lauren Kovarick

Richard T. Schellhase Essay Prize in Ethics

The antagonistic relationship between a mother and their unborn child creates the controversial topic of abortion. With massive moral implications and consequences associated, education on the laws and reasoning is significant to determine the direction of society. To analyze the ethics of abortion, the bioethical and metaphysical debate must be considered. With the former, the four principles of bioethics are used in healthcare practice to break down an ethical concern. On the metaphysical side, the life-status and rights of the fetus are acknowledged. With this topic, it is important not to argue in favor of one position, but instead have …

Returning To Sexual Activity And Intimacy After Spinal Cord Injury, Hanna Bush

Occupational Therapy Doctoral Student Capstone Posters

Sexual activity and intimacy are meaningful occupations for many individuals, regardless of ability. According to the OTPF-4, sexual activity and intimacy are activities of daily living. It is also a right for persons to have access to engage in meaningful activities. However, there is significant information reported that individuals with spinal cord injuries are not receiving sufficient, or any, information for returning to sexual activity during occupational therapy treatment. A program manual, educational materials, and handouts were designed for those with spinal cord injuries seeking to return to the ADL of sexual activity and intimacy upon discharge from inpatient rehabilitation.

Adaptive Outdoor Recreation To Promote Health And Well-Being For Adults With Disabilities, Brittany Earle

Occupational Therapy Doctoral Student Capstone Posters

Individuals with physical disabilities are disproportionately excluded from leisure pursuits including outdoor recreation due to various barriers. In collaboration with Cleveland Metroparks, I created a program designed for adults with disabilities to enhance health and well-being through participation in outdoor recreation as well as increase awareness of opportunities available. The Adaptive Outdoor Recreation Program is intended to be implemented in spring 2025.

Empowering Fall Prevention: Development And Implementation Of Volunteer Peer Liaison Program Manual, Marissa Poalson

Occupational Therapy Doctoral Student Capstone Posters

This capstone project addressed the community's lack of knowledge and training in fall prevention strategies by developing and implementing a volunteer peer liaison fall prevention manual. The manual outlined guidelines and provided training to support participants of the fall prevention program offered by the Community Partnership on Aging.

Arm And Hand Functional Priorities Of Individuals With Tetraplegia, Ashley Giffen

Occupational Therapy Doctoral Student Capstone Posters

This research-based capstone conducted at MetroHealth Rehabilitation Institute determined specific functional arm and hand priorities among individuals with tetraplegia. The identification of these client values will inform the development of future rehabilitation processes and technological advancements to improve overall quality of life.

Plaay On The Move Manual For Dynamic Floor System, Brittany Henke

Occupational Therapy Doctoral Student Capstone Posters

The dynamic floor is an interactive projector that facilitates play opportunities for children with physical disabilities. The purpose of this capstone was to develop a manual that will be used to assist clinicians with use of the dynamic floor to improve opportunities of play within Cleveland State University's PLAAY on the Move.

Investigating How Children With Autism Respond To Virtual Environments, Mykaela Naragon

Occupational Therapy Doctoral Student Capstone Posters

Over 90% of individuals diagnosed with autism spectrum disorder face sensory processing challenges. Virtual environments can trigger adaptive sensory responses akin to real-world experiences. This preliminary study explored how students with autism interact within virtual settings. Conducted at Julie Billiart Schools, where over 75% of students have autism and sensory differences, the project involved 35 participants aged 6-14 in six VR sessions. Data on Zones of Regulation, affect, and behaviors were collected. Results showed VR was enjoyable, with highly significant post-VR changes in Zone of Regulation (p<0.001). This suggests VR holds promise as a therapeutic tool for self-regulation in children with ASD.

Occupational Therapy's Role In The Area Of Eating Disorders And Body Image, Tayler Arjune

Occupational Therapy Doctoral Student Capstone Posters

The role of Occupational Therapy with the eating disorder and body image population is not widely addressed. This capstone, worked alongside TripleAWellness, to advocate for occupational therapy services within the population of body image and eating disorders by educating clients and staff on occupational engagement and enhancing occupational performance.

Increasing Cultural Inclusivity Within Your Practice: Dei Toolkit For Occupational Therapy Practitioners, Kaitlyn Deere

Occupational Therapy Doctoral Student Capstone Posters

In the world of healthcare, there is an alarming amount of health disparities and lack of access to quality healthcare for those belonging to marginalized communities. The purpose of this capstone was to create a Diversity, Equity, and Inclusion tool kit for the Ohio Occupational Therapy Association that supports an occupational therapy practitioner's journey towards cultural humility.

Development Of A Dating Violence Prevention Program For Adolescents, Melissa Arellano

Occupational Therapy Doctoral Student Capstone Posters

This capstone focused on the development of an 8-session program with The Journey Center for Safety and Healing that aims to empower high school-aged adolescents through activity and leisure-based sessions to develop skills and routines to promote healthy dating by recognizing dating abuse, by developing social and emotional skills, and ultimately working to promote safe and healthy relationships and reduce instances of intimate partner violence.

Occupational Therapy And Human Trafficking Recovery: A Novel Educational Model, Jacklyn Voytko

Occupational Therapy Doctoral Student Capstone Posters

Human trafficking recovery frequently fails to address the complex needs of survivors. Occupational therapy is uniquely qualified to meet those needs, but is commonly overlooked. This capstone involved the development of an evidence-based educational model, emphasizing trauma-informed and culturally responsive practice, to increase occupational therapists’ knowledge on their role in ending the cycle of exploitation.

The Truth To Transitioning: Development Of A Trans* Specific Occupational Therapy Practice Framework Involving An Integrative Care Model, Amanda Gale

Occupational Therapy Doctoral Student Capstone Posters

Transgender and gender-diverse (TGD) clients are underserved by occupational therapy practitioners (OTPs) throughout their transition journey. This research based capstone involved completing stakeholder interviews with OTPs and TGD individuals to inform and update an existing occupational therapy model and improve best-practice standards within OT practice when providing services to TGD individuals.

Improving Community Integration Through A Leisure Program To Address Cyclic Veteran Homelessness., Breeanna Host

Occupational Therapy Doctoral Student Capstone Posters

This capstone worked to provide increased leisure opportunities and build leisure skills for homeless veterans through the development of a leisure program and community speaker series at Harry Donovan Jr. Valor Home. This program focused on improving community integration and quality of life through leisure education and hands on experiences.

Student-Athletes And Their Hidden Opponent: Assessing And Supporting Student-Athlete Mental Health And Well-Being, Dena Wenzinger

Occupational Therapy Doctoral Student Capstone Posters

Suicide is now the second most common cause of death among college athletes in the United States. This capstone involved conducting an in-depth needs assessment of the mental health resources in the Athletics Department at Cleveland State University. There was a collaboration with the Student-Athlete Academic Services staff and the Athletics Counselor to provide mental health resources reported to be needed by the student-athletes (SAs). This population can benefit from occupational therapy intervention as occupational therapists are educated on mental health practices. Resources were created and made available to the SAs on their “Community for Student-Athlete Engagement” Blackboard course.

Implementation Of Ot Services Through A Reverse Job Fair For Adults With Intellectual And Developmental Disabilities (Idd), Rachel Braunegg

Occupational Therapy Doctoral Student Capstone Posters

Employment rates for adults with developmental and intellectual disabilities (IDD) is extremely low, despite having the desire and skill sets to work (Friedman, 2019). This capstone, partnering with Cleveland State University's Center for Career Development & Exploration, provided RISE students with IDD an opportunity to prepare for and participate in a Reverse Job Fair through weekly OT intervention.

Promoting Occupational Justice Within An Adaptive Rock Climbing Program, Kate Bliven

Occupational Therapy Doctoral Student Capstone Posters

This capstone project enhanced Rec2Connect's adaptive rock climbing program through a contextual analysis which identified areas for improvement and guided the development of comprehensive resources for facilitators supporting individuals with and without disabilities. The project aimed to enrich engagement on and off the climbing wall, fostering inclusive, meaningful recreation within the program and the greater community.

Universal Guideline Manual (Ugm) For Inclusive Physical Education Service (Pes) Courses At Cleveland State University (Csu), Jamie Bartolovich

Occupational Therapy Doctoral Student Capstone Posters

In collaboration with the Department of Health Sciences and Human Services at Cleveland State University, this capstone included the development and dissemination of a Universal Guideline Manual for physical education instructors at CSU. Incorporating diverse teaching methods and adaptive strategies, this manual equips the instructors with guidance on how to accommodate students of all abilities, ensuring a supportive and enriching classroom environment.

Classroom Reintegration For Children And Adolescents With Traumatic Brain Injuries, Alli Perkins, Mary Greer, Keith Mcwilliams

Spring 2024 Virtual OTD Capstone Symposium

The purpose of the poster presentation is to increase the present knowledge regarding the process of school-based reintegration for children and adolescents who have experienced a traumatic brain injury. As children and young adults spend an average of 32 hours per week in the school environment, parents, educators, and rehabilitation professionals are ideally positioned to collaborate with one another to facilitate the reintegration process and enable students to return to their primary occupations of educational participation, social participation, play, and leisure. The presentation includes information from the development and implementation of a program for parents, families, and educators of those …

Exercise-Induced Myc As An Epigenetic Reprogramming Factor That Combats Skeletal Muscle Aging, Ronald G. Jones Iii, Ferdinand Von Walden, Kevin A. Murach

Health, Human Performance and Recreation Faculty Publications and Presentations

Of the “Yamanaka factors” Oct3/4, Sox2, Klf4, and c-Myc (OSKM), the transcription factor c-Myc (Myc) is the most responsive to exercise in skeletal muscle and is enriched within the muscle fiber. We hypothesize that the pulsatile induction of MYC protein after bouts of exercise can serve to epigenetically reprogram skeletal muscle toward a more resilient and functional state.

Addressing Untimely Healthcare Access Of Veterans Receiving Care Through The Veteran Healthcare Administration (Vha), Frank Lunetta, Jamie Stern, Lila Mcnamee

School of Professional Studies

The Veteran Healthcare Administration (VHA) serves over nine million veterans (Department of Veterans Affairs, 2023). They are responsible for the health and well-being of veterans with service-connected disabilities (Department of Veterans Affairs, 2023). A major focus for the organization is to keep improving access for veterans, as the population continues to grow (Department of Veterans Affairs, 2023). In 2018, congress passed the MISSION Act in hopes of increasing access for veterans. The MISSION Act would expand private healthcare access for veterans through the Veteran Community Care Program (VCCP) (MISSION ACT, 2018). Despite the initial benefits of the program, the MISSION …

Comparing Effectiveness Of Intrauterine Devices Versus Oral Contraceptives For Management Of Dysmenorrhea, Mackenzie Holland

Physician Assistant Scholarly Project Posters

The purpose of this research and systematic literature review is to determine if oral contraceptives or intrauterine devices are more effective in the treatment of dysmenorrhea pain. It is estimated that at least 50% of women worldwide live with dysmenorrhea and there is very little research determining what the best treatment options are for it. The main treatment recommended by health care providers for dysmenorrhea are non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen. However, this treatment option may not provide the relief that women with this condition need. This review used three main databases, including PubMed, Embase, and Clinical Key …