Medicine and Health Sciences Commons^™

Death Becomes Us: The Consumptive Body In Nineteenth-Century Gothic Literature, Jennifer Marie Mcmahon

All NMU Master's Theses

This thesis examines the impacts of nineteenth-century tuberculosis epidemics on gothic literature published between 1842 and 1872. In this period of time, tuberculosis was the leading cause of death in the United States and in Europe, killing an estimated one in seven people. Using theoretical lenses of psychoanalysis and material ecocriticism, this project considers borders between material bodies—specifically those between bacterial agents and humans—to be illusory and socially constructed. The first chapter focuses on the ways in which representations of tuberculosis, and its associated entanglement with the environment, appear in the work of two authors from the United States: Edgar …

Discussion Boards - What To Blog About?, Leanne Harris

Case studies: Digital Education

Discussion boards in Brightspace afford users the opportunity to engage in meaningful virtual communication. The implementation of discussion boards facilitates access to an online platform that allows students to think, discuss and critically evaluate their discipline. Not only does it enhance digital literacy skills, but it also aids in the development of critical analysis skills, writing skills and reflective thinking skills. This technology links well with the TU Dublin graduate attributes to encourage students to become digitally capable lifelong learners. The EU policy entitled the Digital Education Action Plan 2021-2027 emphasises the need for digitally competent and flexible graduates that …

A Collective Approach: Enhancing Population Health And Social Drivers Of Health Through Interprofessional Education And Collaboration, Arvie Vitente

Philippine Journal of Physical Therapy

No abstract provided.

Interprofessional Education And Collaboration In The Philippines: Current Landscape, Gaps, And Propositions, Arvie Vitente, Michael Sy, Reeva Ann Sumulong, Anna Karerina Causapin, Jocel Regino

Philippine Journal of Physical Therapy

Interprofessional education (IPE) is a forward-looking strategy in healthcare education that unites students and professionals from various disciplines to enhance interprofessional collaboration (IPC). IPE is designed to prepare future health and social care professionals to navigate and address the complexities of modern healthcare systems. In the Philippines, despite being a developing country with a fragmented healthcare system, there have been efforts over the last 15 to 20 years to introduce and institutionalize IPE and IPC in both higher education and healthcare settings. However, significant challenges persist, including the dominance of medical professionals, inadequate regulatory mechanisms, and a lack of strong …

Invited Commentary On Interprofessional Education And Collaboration In The Philippines: Current Landscape, Gaps, And Propositions, Naomi De Aro, Ma. Cecilia Licuan

Philippine Journal of Physical Therapy

No abstract provided.

Physiotherapy In Community-Based Rehabilitation In Middle And Low-Income Countries: A Scoping Review, Er D. Petil Jr., Napoleon R. Caballero

Philippine Journal of Physical Therapy

Introduction: Community-based rehabilitation (CBR) is a widely recognized approach to address the rehabilitation needs of individuals with disabilities in low- and middle-income countries (LMICs). Physical therapy (PT) plays a crucial role within CBR programs. This study aimed to synthesize the current state of literature regarding the integration of PT in CBR programs in LMICs across Asia, Africa, and Latin America, examining key characteristics, reported outcomes, and challenges to implementation.

Methods: A comprehensive review of literature was conducted, focusing on studies published in the past decade. Data were extracted and synthesized in matrix format to compare and contrast findings across the …

Improving Medication Adherence For Post-Operative Pediatric Patients With Spanish-Speaking Caregivers Using A Written Medication Action Plan, Carissa Vicente

Doctor of Nursing Practice Final Project Abstract

PURPOSE

This project aims to improve written discharge education, medication adherence for pediatric patients, and medication education retention for Spanish-speaking caregivers.

BACKGROUND

The project was implemented in a children’s hospital in the Pediatric Post-Anesthesia Care Unit. The discharge process for post-operative pediatric patients lacked appropriate written medication education for Spanish-speaking families, placing patients at an increased risk for improper medication use.

METHODOLOGY

A quality improvement method utilizing Plan-Do-Study-Act (PDSA) cycles was used for implementation, with three cycles completed. A written Spanish-translation medication action plan (MAP) was implemented during discharge for Spanish-speaking caregivers, including adaptions to an electronic health record version …

Hbv Transmission Knowledge Among Korean-American Chronic Hepatitis B Patients In The United States, Giyoung Lee, Hee-Soon Juon, Eunji Kim, Katherine C Smith, Hie-Won Hann, Mimi Chang, Ann C. Klassen

Division of Gastroenterology and Hepatology Faculty Papers

Chronic hepatitis B (CHB) is a condition that disproportionately affects Asian Americans in the United States. Knowledge of transmission is crucial for CHB patients to practice prevention methods to limit the spread of the hepatitis B virus (HBV), but also live their lives free from unwarranted fears or restrictions. Among Asian CHB patients, several misperceptions about HBV transmission have been identified. This analysis aims to assess the current state of HBV knowledge among a cohort of Korean-American CHB patients. This mixed-methods study includes 363 respondents who completed a survey in either Korean (N = 298) or English (N = 65) …

Pericardial Effusion Associated With Direct Oral Anticoagulant Use In A Single Center Experience, Jessica Song, Mark Jaradeh, William Xu, Andres Deluna, Rajkumar J. Sevak, Clifford Wang, Susan X. Zhao

Pacific Faculty Work

Background: Pericardial effusion (PEff) has been described to occur in association with direct oral anticoagulant (DOAC). Objectives: The purpose of this study was to assess the incidence, characteristics, and predisposing factors of PEff associated with DOACs. Methods: In this retrospective single center study, multivariable logistic regression analysis was used to identify factors associated with PEff in adult patients (age ≥18 years) in the Santa Clara Health System between 2013 and 2023. Results: Of the 456 patients with at least small to moderate PEff, 50 were on DOACs (DOAC PEff), 16 on warfarin (warfarin PEff), and 390 with no anticoagulation (NA …

Frequency Of Variants In Mendelian Alzheimer’S Disease Genes Within The Alzheimer’S Disease Sequencing Project, Dongyu Wang, Alexandra Scalici, Yanbing Wang, Honghuang Lin, Achilleas Pitsillides, Nancy Heard-Costa, Carlos Cruchaga, Ellen Ziegemeier, Joshua C Bis, Myriam Fornage, Eric Boerwinkle, Philip L De Jager, Ellen Wijsman, Josée Dupuis, Alan E Renton, Sudha Seshadri, Alison M Goate, Alzheimer's Disease Neuroimaging Initiative (Adni), The Alzheimer's Disease Sequencing Project, Anita L Destefano, Gina M Peloso

Faculty, Staff and Student Publications

Background:

Prior studies examined variants within presenilin-2 (PSEN2), presenilin-1 (PSEN1), and amyloid precursor protein (APP) genes. However, previously-reported clinically-relevant variants and other predicted damaging missense (DM) variants have not been characterized in a newer release of the Alzheimer’s Disease Sequencing Project (ADSP).

Objective:

To characterize previously-reported clinically-relevant variants and DM variants in PSEN2, PSEN1, APP within the participants from the ADSP.

Methods:

We identified rare variants (MAF< 1%) in PSEN2, PSEN1, and APP in 14,641 individuals with whole genome sequencing and 16,849 individuals with whole exome sequencing available (Ntotal = 31,490). We additionally curated …

Protective Factors Against Child Maltreatment Among Postpartum Mothers, Maggie Mann, Elizabeth Grady, Matthew Hall, Cristy Toburen, Ann Mattison, Jennifer Anderson, Katie J. Hocker, Francesca Donohue, Heather Williams, Jessica Sprague-Jones, James Anderst, Henry T. Puls

Presentations

No abstract provided.

Aht Diagnoses: The Influences Of Clinical Presentation And Evidence Of Impact, Ruairi Smith-Dewey, Angela Bachim, Colleen Bressler, Kristine A. Campbell, Lori Frasier, Chris Greenley, Danielle Horton, Nicole R. Johnson, Jan Leonard, Megan M. Letson, Dan M. Lindberg, Caitlin R. Mcnamara, Shalon M. Nienow, Ashley K. Sherman, Joanne N. Wood, James Anderst Md, Msci

Presentations

In cases where Child Abuse Pediatricians (CAPs) diagnose abusive head trauma (AHT) in young children, some factors surrounding the diagnosis have been challenged including causative shaking, necessity of external signs of impact, or concomitant suspicious injuries. Evaluation of CAP diagnoses in children with subdural hemorrhage (SDH) can give insight into factors related to the frequency of abusive head trauma (AHT) diagnoses. Additionally, characterization of those with SDH+CSI without evidence of impact may inform controversies around AHT diagnoses. Objective We aim to compare CAP diagnoses in subjects with SDH across clinical presentations and in the context of evidence of head impact. …

Mental Health Diagnoses Amongst Children With Complex Chronic Medical Conditions, Maria Newmaster, Matt Hall, Adrienne Deporre, Molly Krager, Cy Nadler, Laura Plencner, Henry T. Puls

Presentations

Background: Mental health (MH) diagnoses are known to complicate outcomes of underlying medical conditions in pediatrics, but the prevalence of MH diagnoses across the array of medically complex and/or chronic conditions are not well known. Objective: To compare prevalence of MH diagnoses across levels of medical complexity and chronicity, and identify factors associated with MH diagnoses among children with complex chronic conditions (CCC). Methods: This retrospective cross-sectional study included children ages 5-17 years with at least 11 months of continuous Medicaid enrollment in 2022 from the Merative Marketscan Medicaid Database which collects data from all children with Medicaid in the …

Variation In Blood Culture Testing For Three Common Infections, Smit Shah, Jennifer Goldman, Matt Hall, Jillian Cotter, Samantha A. House, Matthew J. Molloy, Michelle Polich, Michael J. Steiner, John R. Stephens, Michael J. Tchou, Ronald J. Teufel Ii, Irma Ugalde, Andrew Yu, Jessica L. Markham

Presentations

Background: Routine blood culture (BC) testing in uncomplicated community-acquired pneumonia (CAP), skin and soft tissue infections (SSTI), and urinary tract infections (UTI) has demonstrated low clinical utility. Objectives: To evaluate hospital-level BC testing trends and their association with clinical outcome differences for children hospitalized with CAP, SSTI, and UTI. Methods: This retrospective cohort study used the Pediatric Health Information System database to identify hospitalizations of children aged 3 months-18 years admitted with CAP, SSTI, or UTI from 2016-2023. We excluded patients with complicated infections, medical complexity, ICU admission, or length of stay (LOS) >7 days. Hospital-level BC testing rates were …

Medicaid Patient Experiences With Nurse Practitioners And Other Providers: A Big Data Analysis, Deanna Jan Emory, Thomas A. Kippenbrock

The Eleanor Mann School of Nursing Faculty Publications and Presentations

There is a current and ongoing shortage of primary care providers that is projected to increase through 2034. Over the last decade, this shortage has resulted in increased reliance on nurse practitioners and physician assistants to fill the gap. The pur-pose of this study was to investigate Medicaid recipients’ experiences with their respective primary care providers using responses from the Consumer Assessment of Healthcare Providers and Systems database with a focus on nurse practitioners compared to other provider types identified. Responses from 68,761 Medicaid recipients were analyzed. The results showed that Medicaid recipients’ scores for nurse practitioners were comparable to …

Steroid Receptors And Coregulators: Dissemination Of Sex Differences And Emerging Technologies, Sally Pauss, Evelyn A. Bates, Genesee J. Martinez, Zane T. Bates, Zachary A. Kipp, Cassandra D. Gipson, Terry D. Hinds Jr.

Markey Cancer Center Faculty Publications

Steroid receptors are ligand-induced transcription factors that have broad functions among all living animal species, ranging from control of sex differences, body weight, stress responses, and many others. Their binding to coregulator proteins is regulated by corepressors and coactivators that interchange upon stimulation with a ligand. Coregulator proteins are an imperative and understudied aspect of steroid receptor signaling. Here, we discuss steroid receptor basics from protein domain structures that allow them to interact with coregulators and other proteins, their essential functions as transcription factors, and other elemental protein–protein interactions. We deliberate about the mechanisms that coregulators control in steroid receptor …

Lysyl Hydroxylase 2 Glucosylates Collagen Vi To Drive Lung Cancer Progression, Shike Wang, Houfu Guo, Reo Fukushima, Masahiko Terajima, Min Liu, Guan-Yu Xiao, Lenka Koudelková, Chao Wu, Xin Liu, Jiang Yu, Emma Burris, Jun Xu, Alvise Schiavinato, William K. Russell, Mitsuo Yamauchi, Xiaochao Tan

Markey Cancer Center Faculty Publications

Lysyl hydroxylase 2 (LH2) is highly expressed in multiple tumor types and accelerates disease progression by hydroxylating lysine residues on fibrillar collagen telopeptides to generate stable collagen cross links in tumor stroma. Here, we show that a galactosylhydroxylysyl glucosyltransferase (GGT) domain on LH2 modified type-VI collagen (Col6) to promote lung adenocarcinoma (LUAD) growth and metastasis. In tumors generated by LUAD cells lacking LH2 GGT domain activity, stroma was less stiff, and stable types of collagen cross links were reduced. Mass spectrometric analysis of total and glycosylated peptides in parental and GGT-inactive tumor samples identified Col6 chain α3 (Col6a3), a component …

Shsp Dean's Newsletter, Spring 2025, Robert W. Amler

SHSP Dean’s Newsletter

No abstract provided.

Phytochemicals And Human Health, Erin Kelley Richards

Theses and Dissertations

This review explores the intricate relationship between phytochemical intake and human health. It first highlights the contrast between the phytochemical-poor Standard American Diet (SAD) and ancestral diets rich in diverse plant and animal foods. The classification, sources, and health benefits of various phytochemicals, including polyphenols, flavonoids, alkaloids, and terpenes are described and discussed. The bioavailability of these compounds and their interactions with the gut microbiome are elucidated, emphasizing on their potential in modulating multiple pathways associated with aging and chronic diseases. The 12 hallmarks of aging and how phytochemicals may influence these hallmarks are reviewed. While exploring the potential benefits …

Fnes 203: Meal Planning And Therapeutic Diets, Patrick J. Moran Jr

Open Educational Resources

Application of principles of meal planning to evidence-based therapeutic diets. Lecture and laboratory include menu planning, food cost analysis, therapeutic modifications to recipes, preparation, and service of food in accordance with food safety principles, and effective time management, collaboration, and teamwork in the food production facilities.

Maternal Guilt Following Pediatric Burn Injury, Sabrina Ung, Abby Dugan, Casey Lawless, Mallory Netz, Alec Bernstein, Carisa Parrish

Posters

Background: Previous research has shown that parental guilt is a risk factor for poor parental adjustment (e.g., depression, posttraumatic stress) following a pediatric burn injury (Hawkins et al., 2019). However, few studies have examined risk factors for parental guilt. Objectives/Goal: The current study aimed to examine relationships among demographic variables, burn characteristics, maternal mental health, with maternal guilt following their child’s burn injury. Methods/Design: Mothers of 147 children who experienced a burn injury (mean child age = 6.28 years, 46% female, 44.7% White, 19.2% Black or African American, 9.6% Hispanic, 1.3% Asian, 11.9% multiracial, total body surface area range .10 …

Facilitators, Barriers, & Recommendations For Pediatric Research Sites Conducting Decentralized Clinical Trials (Dcts), Abby Kietzman

Posters

The COVID-19 pandemic drastically altered the way clinical research is conducted through a widespread adoption of telemedicine practices to continue clinical trial procedures during peak periods of global COVID-19 spread. Using telehealth/telemedicine services allows researchers to conduct “decentralized clinical trials”, or DCTs, for all or portions of study protocol procedures while maintaining safety measures implemented for pandemic control. However, research sites are hesitant to adopt DCT policies due to concerns around digital health technology, data safety and quality, and limited information in the literature specifically assessing telemedicine use for pediatric clinical research via DCTs or how equipped pediatric research sites …

Unveiling The Dynamics Of Intersectional Aging: A Qualitative Exploration Of Aging And Social Participation Among Transgender Older Adults, Tiff Cunin

Doctor of Philosophy in Translational Health Sciences Dissertations

For more than thirty years, extensive research has focused on understanding and supporting healthy aging among older adults in the United States. This research has emphasized the importance of community engagement, access to resources, and interpersonal relationships among the broader older adult population, However, it has largely overlooked how transgender older adults experience aging and how those experiences shape their social participation. Additionally, understanding how intersecting marginalized identities—such as race and transgender identity—affect social participation is essential.

This study employed a qualitative multiple case study design to explore the experiences transgender older adults have while aging and how those experiences …

It-Enabled Services In Online Healthcare Platforms, Anqi Zhao

Dissertations and Theses Collection (Open Access)

Despite the growing prevalence of IT-enabled applications and interventions, online healthcare platforms (OHPs) face notable challenges in addressing technological and informational barriers, maintaining patient and physician engagement, and ensuring quality of care. To address these challenges, this dissertation examines the impact of IT-enabled services in OHPs across key stages of the healthcare service process—preconsultation, consultation, and postconsultation.

In the preconsultation stage, we scrutinize the effects of online preconsultation from both physician and patient perspectives. The findings reveal that preconsultation, significantly increases the consultation physician’s response speed,support abundance, and informational support. However, because emotional support is the …

April 2025, Swosu Rural Health Center

RURAL ROCKS

This is the April 2025 issue of Rural Rocks from the SWOSU College of Pharmacy.

Alumni Journal - Volume 96, Number 1, Loma Linda University School Of Medicine

Alumni Journal, School of Medicine

Editorials
2 | From the Editor
4 | From the President
6 | From the Dean

News
7 | This & That
10 | Alumni News
12 | School of Medicine News
14 | AIMS Report: Short-term Mission, Long-term Impact
16 | Student Appreciation
18 | Department Report: Preventative Medicine

APC 2025
20 | Annual Postgraduate Convention (APC) 2025 in Review

Features
34 | Building Connections
36 | Divine Connections
38 | Remembering Ath 'AT' Tuot
42 | Alumni Spotlight: Featuring Janet T. Strausbaugh '78-A
44 | Life After Medicine

In Memoriam
45 | Alumni Remembered: Featured Obituaries: David Tse …

Integrating Mental Health And Substance Use Treatment Using The Integrated Care Model: Policy Analysis, Victoria Reis

Doctor of Nursing Practice Final Project Abstract

Purpose of Statement

Policy analysis evaluates the integration of mental health services into substance use treatment, particularly for co-occurring disorders. It identifies gaps in existing policies and offers recommendations to enhance access, coordination, and effectiveness of integrated care.

Background

Integrating mental health services is crucial due to the high prevalence of co-occurring disorders. However, the fragmented treatment landscape leads to poor patient outcomes and rising healthcare costs. Policies such as the 21st Century Cures Act and Texas House Bill 4 provide a framework for improvement, but significant gaps hinder effective integrated care.

Methodology

Using the Bardach Policy Analysis Framework, this …

The Prevalence Of Suicide And Suicidal Ideation In Adult Oncology Patients, Mutiat Bamiloshin

Doctor of Nursing Practice Final Project Abstract

Objective

The aim of this quality improvement initiative is to implement the Columbia-Suicide Severity Rating Scale (C-SSRS) to enhance the early detection of suicide risk among adult oncology patients and to facilitate timely referrals for mental health support.

Background

Adult cancer patients experience substantial psychological distress due to the challenges related to their diagnoses and treatments, significantly increasing their suicide risk. The lack of routine suicide screenings in oncology settings impedes the early identification of at-risk patients, necessitating evidence-based approaches.

Methodology

The project involved 50 adult oncology patients and was conducted at a hospital in Texas over eight weeks. Weekly …

N Y State Dent J April 2025

The New York State Dental Journal

In the April 2025 issue, the reader will find the following feature articles:

• Treatment Options for Pre-eruptive Intracoronal Resorption of Permanent Teeth: A Report of Two Cases
• Successful Treatment of a “Pedo-Endo” Lesion in a Primary First Molar
• Comparison of Untreated Caries and Caries-Risk Improvement in an Elementary-School-Based Comprehensive Dental Care Program

This issue includes regular columns with regional news impacting the New York membership including: editorial and perspectives columns, legal, association activities, component news, continuing education opportunities, and classifieds.

Michigan Can Be Proud Of Dentistry's Volunteers, Michelle C. Dziurgot

The Journal of the Michigan Dental Association

This editorial celebrates National Volunteer Week (April 20-26, 2025) by highlighting Michigan Dental Association members' volunteer contributions. The article emphasizes dentists' participation in MDA Foundation's Missions of Mercy programs providing free dental care, involvement in organized dentistry through committees and events, and recognition through various MDA awards. The author acknowledges members' non-dental community service and expresses gratitude for volunteers whose dedication strengthens the MDA and provides essential dental care to underserved populations across Michigan.