Medicine and Health Sciences Commons^™

Nourishing The Body, Nurturing The Soul, Vidhi Raval

be Still

No abstract provided.

Our Sacred Oath, Jeffrey Joppen, Nisha Patel

be Still

We both tried to find a photograph that could demonstrate what our sacred oath to healing looked like. The stethoscopes symbolize this because they represent more than just a tool for auscultation, they are objects that directly connect a healthcare provider to their patient. When we place the stethoscope on our patient’s chest we listen to their heart and lung sounds and the unique vibrations and rhythms that the individual makes. This action demonstrates deep trust and responsibility for healing.

Frankenstein Colorized, Marianne Koleng

be Still

One of my favorite novel's growing up was Mary Shelley's Frankenstein. I see Frankenstein's desire to create a "Monster" as a way to grasp at the fundamental human drive for connection, and healing through connection. In this piece, I attempt to bring that inner yearning for fundamental connection to paper.

Beyond Myself - Healing Through Pain, Marianne Koleng

be Still

In this piece I reflect on the importance of setbacks, non-linear growth, injuries, and pain and their ability to provide self-reflection, a platform for growth, and an crucial reminder of the fragility of life. I have often been self-critical for not following a "traditional" path in life, and reflecting on my experiences allows me to show myself grace and hopefully may influence others to do so as well.

The Orchard Of Golden Apples, Ambika Kapil, Brendan Ginsberg

be Still

This poem was written collaboratively by Ambika Kapil and Brendan Ginsberg, reflecting our shared journey through the challenges and rewards of medical school. The inspiration for this piece comes from a pivotal time in Ambika's journey, when she found herself balancing the demands of medical education with personal struggles. During this period, she often turned to the lectures and guidance of various faculty members, including Dr. Lori Dribin, whose wisdom and support provided a sense of stability and hope. The guidance of these mentors became a beacon, helping Ambika navigate through uncertainty.

As many students face an array of challenges …

The Sacrifices Of Being Away, Claudia Pedreira

be Still

No abstract provided.

Remedios De Abuela: Sacred Traditions Of Healing, Madeline R. Sardinas

be Still

Remedios de Abuela is a narrative-style essay reflecting on the Cuban remedies and family caregiving practices that shaped my journey into medicine. From the warmth of sopa de pollo to the soothing ritual of Vicks VapoRub, these traditions embody the sacred oath of healing.

Through personal stories, including caring for my grandfather with diabetes, this essay explores the intersection of family, culture, and the art of medicine. It is a tribute to my grandparents and a testament to the enduring power of traditions and the human connection at the heart of the healing profession.

Death Is Not The End, Marianne Koleng

be Still

In this piece, Death is Not the End, the juxtaposition of maintaining a connection with those lost, while simultaneously adjusting to life without them is explored. The use of mixed media to convey a spectrum of emotions surrounding death along with the use of both a skeleton, to represent death, and "normal" hands and body contours to represent life, highlight the importance that proper healing play in both mourning and celebrating life.

2025 Research Day Program, Lincoln Memorial University

Research Day

This program contains poster presentation summaries from LMU's 2025 Annual Research Day conference.

Are Hcc Risk Scores A Reliable Health Status Indicator Across Rural And Urban Areas?, Craig D. Holden, Alana Knudson, Marilyn Klug, Samantha Augenbraun, Shena Popat

ETSU/NORC Rural Health Research Center Policy Briefs

No abstract provided.

A Cellular And Molecular Dissection Of The Breast: Identification Of Pericytes As A Driver Of Tumor Cell Proliferation, Katelyn M. Del Toro

Biomedical Sciences ETDs

Tissues are composed of many different types of cells. Each has a specific function and exists within a unique context—all of which define the landscape of the tissue. The cellular and molecular interactions within a tissue are critical to its form and function. Defining these interactions is an important step in understanding the aberrant nature of diseases like cancer, where tissue homeostasis has been abandoned. This requires reliable models of each cell type. Yet, in many tissues, including the breast, comprehensive methods to identify, purify, and study each tissue cell type have not been defined. This is a critical deficiency …

Larotrectinib Compared With Real-World Non-Tropomyosin Receptor Kinase Inhibitor Therapies In Patients With Tropomyosin Receptor Kinase Fusion Cancer, Marcia S. Brose, C. Benedikt Westphalen, Xiaoyun Pan, Vadim Bernard-Gauthier, Milena Kurtinecz, Helen Guo, Virginie Aris, Neil R. Brett, Abdelali Majdi, Vivek Subbiah, Nathan A. Pennell, Kenneth L. Kehl, Alexander Drilon

Kimmel Cancer Center Faculty Papers

PURPOSE: Neurotrophic tyrosine receptor kinase gene fusions are oncogenic drivers of various solid tumors. Larotrectinib is a highly selective tropomyosin receptor kinase (TRK) inhibitor approved for patients with TRK fusion cancer on the basis of single-arm trials. This study was a matched comparative effectiveness study of larotrectinib in clinical trials versus standard of care (SOC) in the real-world (RW) setting.

METHODS: Adult patients with advanced/metastatic TRK fusion non-small cell lung cancer, colorectal cancer, soft tissue sarcoma, thyroid cancer, or salivary gland carcinoma were included. Deduplicated data from RW patients were from US and ex-US data sources. Patients in the larotrectinib …

Vpac Receptor Positivity In Comparison With Mp-Mri In The Diagnosis Of Prostate Cancer: A Preliminary Study, Nishant Setya, Shridhar Ghagane, Rajendra Nerli, Ashwin Bokare, Mathew Thakur, Leonard Gomella

Kimmel Cancer Center Faculty Papers

Objective: The study aimed to prospectively evaluate the feasibility of diagnosing PCa using voided urine samples and by targeting the genomic VPAC (vasoactive intestinal peptide and pituitary adenylate cyclase-activating peptide) receptors in comparison with multiparametric magnetic resonance imaging (mp-MRI) in male patients (≥40 years of age) with lower urinary tract symptoms and having a serum PSA of >4 but < 15 ng/ml.

Patients and methods: Male patients attending urological services ≥40 years old, with lower urinary tract symptoms and serum PSA levels of >4 but < 15 ng/ml formed the study group. Voided urine samples were collected to target VPAC receptors on malignant cells. All patients underwent mp-MRI. A 12-core transrectal ultrasound-guided prostate biopsy was performed in all, and the results were compared for the diagnosis of PCa.

Results: A total of 61 patients with a median age of 65.33 ± 8.11 years and with a …

Short-Course Subcutaneous Alemtuzumab Induces Clinical Responses In Relapsed T-Cell Large Granular Leukemia, Miguel Ruiz, Zachary Braunstein, Eric Mclaughlin, Anjali Mishra, Pierluigi Porcu, Jonathan E. Brammer

Department of Medical Oncology Faculty Papers

No abstract provided.

Experiences And Attitudes Of Caregivers During Mealtimes In Children With Autism Spectrum Disorder At A Tertiary Facility In Kenya., Lynnette Muthoni Mwangi

Master of Medicine in Paediatrics and Child Health

Introduction: - ASD is a neurodevelopmental disorder characterized by deficits in social interactions and communication along with restrictive and repetitive behaviours affecting 1 in 100 children globally, with a higher prevalence in males. Despite the rising global statistics, there is limited information regarding the prevalence of ASD in Sub-Saharan Africa. Children with ASD often experience feeding challenges, which have been broadly categorized as food selectivity, food refusal, and disruptive mealtime behaviour, which poses challenges for caregivers during mealtime. While medical management of ASD receives considerable attention, less focus has been placed on the impact of ASD on caregivers and …

A Wellness And Social Engagement Program For Post-Lower Limb Amputees, Graciela Gonzalez, Cassandra Nelson

Spring 2025 OTD Capstone Symposium

A wellness and social engagement program was developed and implemented to provide education relating to the mental health impacts, decrease in health management, and lack of social participation after a lower-limb amputation amongst adults, 18 years or older. The program provided a manual with educational information, external resources, and visual aids to enhance independence in activities of daily living (ADLs).

What's Missing From Value-Based Care-Accounting For The Costs And Benefits Of Quality Improvement, Donald E. Casey

College of Population Health Faculty Papers

No abstract provided.

Hubungan Dukungan Sosial Rekan Kerja Dengan Stres Kerja (Studi Pada Pekerja Di Pt X), Aisyah Permatasari

Jurnal Ilmu Kesejahteraan Sosial

Workers are vulnerable to work-related stress due to job demands, time constraints, and limited leisure time, leading to psychological issues such as anxiety related to their work. In the context of social welfare studies, job stress affects overall workers’ well-being and disrupts their social functioning in the workplace. Social support from coworkers is potentially reduce stress in workplace, which is crucial for creating organizational well-being. It also helps workers improve job engagement, cope with fatigue, and manage stress. This study examined the relationship between social support from coworkers and job stress among 90 employees …

Caring Across Borders: Demographic Shifts And Migrant Care In Asean-Korea Dynamics, Saqib Fardan Ahmada, Wahid Nur Kartiko

Jurnal Ilmu Kesejahteraan Sosial

This article aims to examine the migration policies and migrant care in the context of relations between ASEAN Member States (AMS) and Korea. As Korea is dealing with an aging population, an increase in female labour force participation, and an ultra low fertility rate, caregiving, especially for the elderly, has become a pivotal issue. Besides, the traditional nuclear family structure, which has historically served as the primary caregiver for the elderly, is also losing its prominence. In such demographic shift, migrant care workers from AMS are filling the demand for caregiving in Korea, leading to a cross-border international migration from …

Ibuprofen, Flurbiprofen Or Naproxen Sodium Minimally Influences Musculoskeletal Adaptations To Treadmill Exercise In Rats, Brandon Roberts, Alyssa Geddis, Alexandra Ciuciu, Marinaliz Reynoso, Nikhil Mehta, Alyssa Varanoske, Alyssa Kelley, Maximus Leiss, Alexander Kolb, Julie Hughes, Marshall Naimo, Ryan Tomlinson, Jeffery Staab

Department of Orthopaedic Surgery Faculty Papers

BACKGROUND: Non-steroidal anti-inflammatory drugs (NSAIDs) may influence musculoskeletal health. The purpose of this study was to compare the effects of three different NSAIDS: naproxen sodium, ibuprofen, flurbiprofen or a placebo on musculoskeletal adaptations in rodents with or without 6 weeks of aerobic exercise.

METHODS: Nine-week-old male Wistar rats (n = 80) were randomized to either exercise (EX) or no-exercise control (CON) conditions and treated with naproxen, ibuprofen (IBU), flurbiprofen (FLU) or placebo (PLA). For exercise, rats ran 5 days per week for 6 weeks at a 5% incline on a motorized treadmill for 30 min. Three-point bending (3 PB) and …

The Multiple Roles Of 5-Lo In Tissue Regeneration – Insights From Translational Animal Models Utilizing Pharmacological And Genetic Approaches, Roel Navarro, Nidhin John, Claudia Biguetti

School of Podiatric Medicine - Student Research

Inflammation following tissue injury is a natural physiological response, where its course, duration, and intensity help determine whether it promotes beneficial or detrimental outcomes in tissue healing. Arachidonic acid (AA) serves as a substrate for5-lipoxygenase (5-LO) pathway, which synthesizes metabolites such as leukotrienes that influence both acute and chronic inflammatory response.  AA and its product's inhibitors are currently used to treat hypersensitivity reactions. However, literature suggests potential therapeutic efficacy in tissue healing.

Increased Rates Of Dysphagia, Longer Length Of Stay, Nonroutine Discharge, And Higher Hospital Costs In Patients Over 65 Undergoing Single-Level Cervical Disc Arthroplasty: A Propensity Score-Matched Analysis, Paul G. Mastrokostas, Leonidas E. Mastrokostas, Ahmed K. Emara, Ian J. Wellington, Elizabeth Ginalis, Jonathan Dalton, Amrit S. Khalsa, Jad Bou Monsef, Afshin E. Razi, Mitchell K. Ng

Rothman Institute Papers

CONTEXT: Cervical disc arthroplasty (CDA) is a safe and effective treatment for cervical spine conditions, with increasing utilization. As the population over 65 grows, understanding the suitability of CDA in older patients is critical.

AIMS: This study evaluates differences in postoperative complications, hospital course, and costs between patients aged 18 and 65 and those over 65 undergoing CDA.

SETTINGS AND DESIGN: This was a retrospective cohort study using the National Inpatient Sample, a nationally representative database of U.S. hospital discharges.

SUBJECTS AND METHODS: Patients undergoing single-level CDA from 2016 to 2020 were identified. The cohort was divided into two groups: …

Understanding And Addressing Mental Health In Honors Programs, Gavin D. Hood, Katherine H. Tennis

Journal of the National Collegiate Honors Council Online Archive

Evidence of psychological experiences unique to high-achieving students is examined, revealing prominent themes relating to student mental health including academic identity, perfectionism, imposter syndrome, burnout, and overcommitment. These themes are explored in the context of program feedback from honors students gathered through focus group meetings as part of the program review process. Strategies for reframing failure, normalizing self-care, fostering supportive community, and engaging in nonacademic self-exploration are included. The article closes with suggestions for programmatic interventions that directly address these concerns among high-achieving students. While most honors programs are not positioned to engage in clinical interventions, they can take small …

Proposed Evaluation Of Nonpharmacological Treatments And Therapies For Paclitaxel Based Chemotherapy-Induced Peripheral Neuropathy (Cipn), Mackenzie Lesczcynski

D.U.Quark

Chemotherapy-induced Peripheral Neuropathy (CIPN) is a common complication in breast cancer patients receiving Paclitaxel, a chemotherapeutic agent (1). CIPN symptoms range from numbness to extreme pain and sensitivity in bodily extremities, forcing chemotherapy to be halted (2). The mechanism of this side effect is not well understood and there is no standard pharmacological treatment available to improve effects. Nonpharmacological treatments have been attempted on small patient cohorts, but there are no conclusive findings (3). Due to this, we believe that a comprehensive murine model must be developed in order to assess nonpharmacological treatment efficacy and potential molecular targets for pharmacological …

Psychosocial Factors And Associations With Preventive Cardiovascular Screening Among U.S Adults: Findings From The National Health Interview Survey, 2023☆, Osayande Agbonlahor, Abigail Gamble, Caroline Compretta, Joshua R. Mann, Fazlay Faruque

Preventive Medicine Publications

Objective: Structural and COVID-related factors have been linked with the decline in preventive health screenings among adults. However, associations between psychosocial factors and undergoing preventive cardiovascular screening are not fully known. The current study examined associations between psychosocial factors and preventive cardiovascular screening among U.S. adults. Methods: We used data from the 2023 National Health Interview Survey (N = 23,428). Data were collected from January to December from adults living in U.S. Preventive cardiovascular (CV) screening (i.e., blood pressure, cholesterol, or blood sugar level) was defined as no screening, and undergoing screening for any CV risk within the past year. …

Ccr7 Regulated Mechanisms That Limit The Adaptive Immune Response, Jaisel Amilcar Cervantes

Open Access Theses & Dissertations

C-C chemokine receptor 7 (CCR7) is critical in guiding T cell migration within the thymus and peripheral lymphoid tissues, shaping the adaptive immune response by promoting central tolerance and regulating immune homeostasis. Although its role in lymphocyte trafficking is well established, the molecular mechanisms by which CCR7 influences thymocyte development and T cell receptor (TCR) repertoire formation remain less understood. This study examines how CCR7 deficiency impacts thymic selection, TCR diversity, and the signaling events that shape repertoire restriction. Using a homozygously deleted CCR7 murine model, we found that the absence of CCR7 results in a less restricted TCR repertoire …

Exploring The Potential Of No-Code Artificial Intelligence In Identifying Periapical Radiolucent Lesions, Marguerite Miller

Master's Theses (2009 -)

ABSTRACT EXPLORING THE POTENTIAL OF NO-CODE ARTIFICIAL INTELLIGENCE IN IDENTIFYING PERIAPICAL RADIOLUCENT LESIONS Marguerite Miller, D.M.D. Marquette University, 2025 Title: Exploring the Potential of No-Code Artificial Intelligence in Identifying Periapical Radiolucent Lesions. Objective: To employ a no-code platform for the development of an AI model designed to identify periapical radiolucent lesions using periapical radiographs. Methods: Three hundred twelve periapical radiographs were retrospectively collected, along with corroborating cone-beam computed tomography (CBCT) volumes and radiology reports obtained within six months. Radiology reports from board-certified oral and maxillofacial radiologists, were used as the reference standard for labeling the periapical radiographs. Among these, 180 …

Long-Term Bone Changes At Edentulous Sites, Teerarat Neal Phuatrakoon

Master's Theses (2009 -)

BACKGROUND: Tooth loss is a debilitating occurrence that may affect the patient’s emotional and mental well-being. Delays in necessary restorative treatment may occur dependent on the patient’s finances or other elaborate dental treatment plans. Prosthetically guided implants have become the standard of care regarding definitive treatment, however there is a lack of evidence discussing the stability of edentulous sites if deferment of treatment is required. OBJECTIVE: The aim of this study is to measure long-term changes of the edentulous alveolar ridge (height and width) and anatomical structures (e.g. sinus floor, inferior alveolar canal). METHODS: Charts of patients with at least …

Comparison Of Hand-Wrist And Cvms Methods For Craniofacial Growth Spurt Assessment, Ardita Ajvazi

Master's Theses (2009 -)

Objective: Hand-wrist (HW) radiographs are considered the most accurate method for assessing pubertal growth spurts in orthodontics but have declined in use due to added radiation exposure and the expertise required. Cervical vertebral maturation staging (CVMS) is now commonly used, given the routine availability of lateral cephalograms. However, the validity of CVMS remains uncertain. A recent study reported only 66% inter-observer reliability across time periods (Ingersoll, 2024). This follow-up study aims to evaluate CVMS as a predictor of growth to guide clinical decision-making. Methods: With protocol approval (MU HR-4695), this retrospective study followed a design modeled after a prior study …

The Interplay Between Endothelial Glycocalyx Maturity And Both The Toxicity And Intracellular Uptake Of Charged Nanoparticles, Claire A. Bridges, Lu Fu, Jonathan Yeow, Xiaojing Huang, Miriam Jackson, Rhiannon P. Kuchel, James D. Sterling, Shenda M. Baker, Megan S. Lord

Business and Information Technology Faculty Research & Creative Works

Nanoparticles are widely studied for delivering treatments to target tissues, but few have reached clinical use. Most nanoparticles encounter blood vessels on their way to target tissues. The inner surface of these vessels is lined with endothelial cells covered by a glycocalyx, an extracellular matrix rich in anionic glycans. The role of the glycocalyx in nanoparticle interactions is not well understood. Here, we demonstrate that endothelial cells need extended culture times to synthesize a mature glycocalyx. Our research shows that branched polyethyleneimine functionalized gold nanoparticles bind to endothelial cells expressing either a developing or mature glycocalyx, with the interaction involving …