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Articles 22561 - 22590 of 325296

Full-Text Articles in Medicine and Health Sciences

Implementation Of A Diabetic Complication Educational Intervention For Staff At A Community-Based Clinic, Virginia K. Dennis Jul 2025

Implementation Of A Diabetic Complication Educational Intervention For Staff At A Community-Based Clinic, Virginia K. Dennis

Walden Dissertations and Doctoral Studies

Even though there are many modalities put in place to manage diabetes and its complications, there have been many barriers to reducing the complications associated with diabetes in health care institutions. In this educational intervention to reduce diabetes and its complications, a staff education program was implemented to enhance staff knowledge about diabetes and the complications associated with it. The staff education program was implemented at a community-based clinic for a DNP-prepared nurse, three RNs, and five medical assistants (MAs) working at the clinic. A pretest and a posttest were administered to assess the impact of the educational session. The …


Who Benefits From Active Music Engagement During Cancer Treatment? Associations Of Sociodemographic Characteristics And Risk Factors With Moderators Of Intervention Effects., Steven J. Holochwost, Elizabeth Harman, Kristin Stegenga, Seethal A. Jacob, Sheri L. Robb Jul 2025

Who Benefits From Active Music Engagement During Cancer Treatment? Associations Of Sociodemographic Characteristics And Risk Factors With Moderators Of Intervention Effects., Steven J. Holochwost, Elizabeth Harman, Kristin Stegenga, Seethal A. Jacob, Sheri L. Robb

Manuscripts, Articles, Book Chapters and Other Papers

Young children and their parents experience frequent and repeated exposure to potentially traumatic events during treatment for cancer. Active Music Engagement (AME) is a dyadic music therapy intervention that has been found to mitigate traumatic stress symptoms among parents who screened high for traumatic stress symptoms (TSS) and reported higher levels of child distress with cancer-related hospitalizations/treatment (child distress). The current study examined sociodemographic characteristics and risk factors that were associated with higher levels of parent TSS and child distress as a means to identify families that may benefit most from AME in the future. Data were collected from the …


Cell Type-Specific Purifying Selection Of Synonymous Mitochondrial Dna Variation, Caleb A Lareau, Patrick Maschmeyer, Yajie Yin, Jacob C Gutierrez, Ryan S Dhindsa, Anne-Sophie Gribling-Burrer, Sebastian Zielinski, Yu-Hsin Hsieh, Lena Nitsch, Veronika Dimitrova, Benan Nalbant, Frank A Buquicchio, Tsion Abay, Robert R Stickels, Jacob C Ulirsch, Patrick Yan, Fangyi Wang, Zhuang Miao, Katalin Sandor, Bence Daniel, Vincent Liu, Paul L Mendez, Petra Knaus, Manpreet Meyer, William J Greenleaf, Anshul Kundaje, Redmond P Smyth, Mathias Munschauer, Leif S Ludwig, Ansuman T Satpathy Jul 2025

Cell Type-Specific Purifying Selection Of Synonymous Mitochondrial Dna Variation, Caleb A Lareau, Patrick Maschmeyer, Yajie Yin, Jacob C Gutierrez, Ryan S Dhindsa, Anne-Sophie Gribling-Burrer, Sebastian Zielinski, Yu-Hsin Hsieh, Lena Nitsch, Veronika Dimitrova, Benan Nalbant, Frank A Buquicchio, Tsion Abay, Robert R Stickels, Jacob C Ulirsch, Patrick Yan, Fangyi Wang, Zhuang Miao, Katalin Sandor, Bence Daniel, Vincent Liu, Paul L Mendez, Petra Knaus, Manpreet Meyer, William J Greenleaf, Anshul Kundaje, Redmond P Smyth, Mathias Munschauer, Leif S Ludwig, Ansuman T Satpathy

Duncan NRI Faculty and Staff Publications

While somatic variants are well-characterized drivers of tumor evolution, their influence on cellular fitness in nonmalignant contexts remains understudied. We identified a mosaic synonymous variant (m.7076A > G) in the mitochondrial DNA (mtDNA)-encoded cytochrome c-oxidase subunit 1 (MT-CO1, p.Gly391=), present at homoplasmy in 47% of immune cells from a healthy donor. Single-cell multiomics revealed strong, lineage-specific selection against the m.7076G allele in CD8+ effector memory T cells, but not other T cell subsets, mirroring patterns of purifying selection of pathogenic mtDNA alleles. The limited anticodon diversity of mitochondrial tRNAs forces m.7076G translation to rely on wobble pairing, unlike the Watson-Crick-Franklin pairing …


Sleep Drive, Not Total Sleep Amount, Increases Seizure Risk, Vishnu Anand Cuddapah, Cynthia T Hsu, Fernanda Valle Sirias, Yongjun Li, Hrishit M Shah, Christopher Saul, Samantha Killiany, Camilo Guevara, Joy Shon, Zhifeng Yue, Gabrielle L Gionet, Mary E Putt, Amita Sehgal Jul 2025

Sleep Drive, Not Total Sleep Amount, Increases Seizure Risk, Vishnu Anand Cuddapah, Cynthia T Hsu, Fernanda Valle Sirias, Yongjun Li, Hrishit M Shah, Christopher Saul, Samantha Killiany, Camilo Guevara, Joy Shon, Zhifeng Yue, Gabrielle L Gionet, Mary E Putt, Amita Sehgal

Duncan NRI Faculty and Staff Publications

Sleep loss has been associated with increased seizure risk since antiquity. Using automated video detection of spontaneous seizures in Drosophila epilepsy models, we show that seizures worsen only when sleep restriction raises homeostatic "sleep drive," not simply when total sleep amount falls. This is supported by the paradoxical finding that acute activation of sleep-promoting circuits worsens seizures, because it increases sleep drive without changing sleep amount. Sleep-promoting circuits become hyperactive after sleep loss and are associated with increased whole-brain activity. During sleep restriction, optogenetic inhibition of sleep-promoting circuits to reduce sleep drive protects against seizures. Downregulation of the 5HT1A serotonin …


Cd45 And Cd148 Are Critically Involved In Neutrophil Recruitment And Function During Inflammatory Arthritis In Mice, Jan-Niklas Heming, Andreas Margraf, Karolina Najder, Giulia Germena, Mathis Richter, Anika Cappenberg, Katharina Henke, Bernadette Bardel, Lena Schemmelmann, Marina Oguama, Pia Lindental, Wida Amini, Jacqueline Sobocik, Georg Schett, Gerhard Krönke, Helena Block, Jan Rossaint, Oliver Soehnlein, Alexander Zarbock Jul 2025

Cd45 And Cd148 Are Critically Involved In Neutrophil Recruitment And Function During Inflammatory Arthritis In Mice, Jan-Niklas Heming, Andreas Margraf, Karolina Najder, Giulia Germena, Mathis Richter, Anika Cappenberg, Katharina Henke, Bernadette Bardel, Lena Schemmelmann, Marina Oguama, Pia Lindental, Wida Amini, Jacqueline Sobocik, Georg Schett, Gerhard Krönke, Helena Block, Jan Rossaint, Oliver Soehnlein, Alexander Zarbock

Faculty, Staff and Student Publications

Neutrophils play a key role in autoimmune diseases like rheumatoid arthritis, contributing to tissue damage through rapid recruitment and activation. In this study, we investigated the regulatory properties of two receptor-like tyrosine phosphatases (RPTPs), CD45 and CD148, in inflammatory arthritis. Using an in vivo mouse model of K/BxN serum transfer-induced arthritis, we found that CD45 and CD148 feature distinct regulatory properties during inflammatory arthritis. CD45 is required for neutrophil infiltration, cytokine release, and reactive oxygen species production, whereas CD148 deficiency leads to a delayed onset of arthritis but unaltered overall neutrophil infiltration and reduced ROS production. Furthermore, we could demonstrate …


Glucose Metabolism And Its Direct Action In Cancer And Immune Regulation: Opportunities And Challenges For Metabolic Targeting, Bo-Syong Pan, Che-Chia Hsu, Hsin-En Wu, Yuan-Ru Chen, Xiaobo Zhou, Shu-Chi Wang, Chia-Yang Li, Hui-Kuan Lin Jul 2025

Glucose Metabolism And Its Direct Action In Cancer And Immune Regulation: Opportunities And Challenges For Metabolic Targeting, Bo-Syong Pan, Che-Chia Hsu, Hsin-En Wu, Yuan-Ru Chen, Xiaobo Zhou, Shu-Chi Wang, Chia-Yang Li, Hui-Kuan Lin

Faculty, Staff and Student Publications

Glucose metabolism is a pivotal hub for cellular energy production and the generation of building blocks that support cell growth, survival, and differentiation. Cancer cells undergo metabolic reprogramming to sustain rapid proliferation, survive in harsh microenvironments, and resist therapies. Beyond producing energy and building blocks to meet cancer cell demands, glucose metabolism generates numerous metabolites that serve as signaling molecules, orchestrating signaling pathways and epigenetic modifications that regulate cancer cell phenotypes and immunity. In this review, we discuss how glucose, through its metabolism and direct actions, influences diverse biological processes driving cancer progression and therapeutic resistance, while also exploring metabolic …


A Data Assimilation Framework For Predicting The Spatiotemporal Response Of High-Grade Gliomas To Chemoradiation, Hugo J M Miniere, David A Hormuth, Ernesto A B F Lima, Maguy Farhat, Bikash Panthi, Holly Langshaw, Mihir D Shanker, Wasif Talpur, Sara Thrower, Jodi Goldman, Sophia Ty, Caroline Chung, Thomas E Yankeelov Jul 2025

A Data Assimilation Framework For Predicting The Spatiotemporal Response Of High-Grade Gliomas To Chemoradiation, Hugo J M Miniere, David A Hormuth, Ernesto A B F Lima, Maguy Farhat, Bikash Panthi, Holly Langshaw, Mihir D Shanker, Wasif Talpur, Sara Thrower, Jodi Goldman, Sophia Ty, Caroline Chung, Thomas E Yankeelov

Faculty, Staff and Student Publications

Background: High-grade gliomas are highly invasive and respond variably to chemoradiation. Accurate, patient-specific predictions of tumor response could enhance treatment planning. We present a novel computational platform that assimilates MRI data to continually predict spatiotemporal tumor changes during chemoradiotherapy.

Methods: Tumor growth and response to chemoradiation was described using a two-species reaction-diffusion model of enhancing and non-enhancing regions of the tumor. Two evaluation scenarios were used to test the predictive accuracy of this model. In scenario 1, the model was calibrated on a patient-specific basis (n = 21) to weekly MRI data during the course of chemoradiotherapy. A data assimilation …


Non-Mutated Human Tau Stimulates Alzheimer’S Disease-Relevant Neurodegeneration In A Microglia-Dependent Manner, Ethan R Roy, Qiang Wang, Kexin Huang, Sanming Li, Yuanyuan Fan, Estrella Escobar, Constance L Atkins, Shuning Huang, Juan J Herrera, Wenbo Li, Clare Pridans, Xiaobo Zhou, Cynthia Ju, Wei Cao Jul 2025

Non-Mutated Human Tau Stimulates Alzheimer’S Disease-Relevant Neurodegeneration In A Microglia-Dependent Manner, Ethan R Roy, Qiang Wang, Kexin Huang, Sanming Li, Yuanyuan Fan, Estrella Escobar, Constance L Atkins, Shuning Huang, Juan J Herrera, Wenbo Li, Clare Pridans, Xiaobo Zhou, Cynthia Ju, Wei Cao

Faculty, Staff and Student Publications

The accumulation of abnormal, non-mutated tau protein is a key pathological hallmark of Alzheimer's disease (AD). Despite its strong association with disease progression, the mechanisms by which tau drives neurodegeneration in the brain remain poorly understood. Here, we selectively expressed non-mutated or mutated human microtubule-associated protein tau (hMAPT) in neurons across the mouse brain and observed neurodegeneration in the hippocampus, especially associated with non-mutated human tau. Single-nuclei RNA sequencing confirmed a selective loss of hippocampal excitatory neurons by the wild-type tau and revealed the upregulation of neurodegeneration-related pathways in the affected populations. The accumulation of phosphorylated tau was accompanied by …


Treatment With Allogenic Mesenchymal Stromal Cells For Moderate To Severe Acute Respiratory Distress Syndrome: A Double-Blind, Placebo-Controlled, Multi-Center, Phase 2b Clinical Trial (Stat), Michael A Matthay, Hanjing Zhou, Aartik Sarma, Narges Alipanah-Lechner, Carolyn Hendrickson, Lucy Z Kornblith, Martin Schreiber, David Zonies, Akram Khan, Bryce Robinson, Nicholas J Johnson, Lorraine B Ware, Oscar Guillamondegui, Jonathan Casey, Laura Moore, Bela Patel, Lillian Kao, Charles E Wade, Erin Fox, Charles Cox, Farrakh Khawanja, Robier Aguillon Prada, Sami Hossri, Rachael Callcut, Timothy Albertson, Kevin L Delucchi, Melanie Mcmillan, Charles R Langelier, Shibani Pati, David H Mckenna, Carolyn Leroux, Carolyn S Calfee, Kathleen D Liu Jul 2025

Treatment With Allogenic Mesenchymal Stromal Cells For Moderate To Severe Acute Respiratory Distress Syndrome: A Double-Blind, Placebo-Controlled, Multi-Center, Phase 2b Clinical Trial (Stat), Michael A Matthay, Hanjing Zhou, Aartik Sarma, Narges Alipanah-Lechner, Carolyn Hendrickson, Lucy Z Kornblith, Martin Schreiber, David Zonies, Akram Khan, Bryce Robinson, Nicholas J Johnson, Lorraine B Ware, Oscar Guillamondegui, Jonathan Casey, Laura Moore, Bela Patel, Lillian Kao, Charles E Wade, Erin Fox, Charles Cox, Farrakh Khawanja, Robier Aguillon Prada, Sami Hossri, Rachael Callcut, Timothy Albertson, Kevin L Delucchi, Melanie Mcmillan, Charles R Langelier, Shibani Pati, David H Mckenna, Carolyn Leroux, Carolyn S Calfee, Kathleen D Liu

Faculty, Staff and Student Publications

Background: Prior clinical trials established the safety, but not the efficacy of bone marrow-derived mesenchymal stromal cells (MSCs) in the acute respiratory distress syndrome (ARDS).

Methods: We conducted a prospective, double-blind, multi-center randomized phase 2b clinical trial of one dose of intravenous MSCs (10 x 106/kg predicted body weight) versus placebo in 120 ventilated patients with ARDS (PaO2/FiO2 < 250 mmHg). The primary endpoint was change in oxygenation index (OI) over 36 hours from baseline.

Findings: Enrollment began in January 2020. Due to the Coronavirus 2019 (COVID-19) pandemic, the majority of subjects (101/120, 84%) developed ARDS from COVID-19. There were no significant baseline differences in severity of illness between patients treated with MSCs and those who received …


Structural Variants: Mechanisms, Mapping, And Interpretation In Human Genetics, Shruti Pande, Moez Dawood, Christopher M Grochowski Jul 2025

Structural Variants: Mechanisms, Mapping, And Interpretation In Human Genetics, Shruti Pande, Moez Dawood, Christopher M Grochowski

Faculty, Staff and Students Publications

Structural variations (SVs) represent genomic variations that involve breakage and rejoining of DNA segments. SVs can alter normal gene dosage, lead to rearrangements of genes and regulatory elements within a topologically associated domain, and potentially contribute to physical traits, genomic disorders, or complex traits. Recent advances in sequencing technologies and bioinformatics have greatly improved SV detection and interpretation at unprecedented resolution and scale. Despite these advances, the functional impact of SVs, the underlying SV mechanism(s) contributing to complex traits, and the technical challenges associated with SV detection and annotation remain active areas of research. This review aims to provide an …


Cd206+Il-4rα+ Macrophages Are Drivers Of Adverse Cardiac Remodeling In Ischemic Cardiomyopathy, Qiongxin Wang, Mohamed Ameen Ismahil, Yujie Zhu, Gregg Rokosh, Tariq Hamid, Guihua Zhou, Steven M. Pogwizd, Sumanth D. Prabhu Jul 2025

Cd206+Il-4rα+ Macrophages Are Drivers Of Adverse Cardiac Remodeling In Ischemic Cardiomyopathy, Qiongxin Wang, Mohamed Ameen Ismahil, Yujie Zhu, Gregg Rokosh, Tariq Hamid, Guihua Zhou, Steven M. Pogwizd, Sumanth D. Prabhu

2020-Current year OA Pubs

BACKGROUND: The role of cardiac CD (cluster of differentiation) 206

METHODS: Adult C57BL/6 mice underwent nonreperfused myocardial infarction to induce HF. Macrophages in murine and human hearts were profiled using flow cytometry and immunostaining. In vivo myeloid-specific IL-4Rα deletion and intramyocardial macrophage adoptive transfer defined the functional effects of macrophages polarized by IL-4 (M[IL-4]). Antisense oligonucleotides were used for in vivo IL-4Rα gene silencing in mice.

RESULTS: CD206

CONCLUSIONS: Cardiac CD206


Xpert Mtb/Rif Ultra Assay For Pulmonary Tuberculosis And Rifampicin Resistance In Adults And Adolescents, David J Horne, Jerry S Zifodya, Adrienne E Shapiro, Elizabeth Chandler Church, Jonah S Kreniske, Alexander W Kay, Katie Scandrett, Karen R Steingart, Yemisi Takwoingi Jul 2025

Xpert Mtb/Rif Ultra Assay For Pulmonary Tuberculosis And Rifampicin Resistance In Adults And Adolescents, David J Horne, Jerry S Zifodya, Adrienne E Shapiro, Elizabeth Chandler Church, Jonah S Kreniske, Alexander W Kay, Katie Scandrett, Karen R Steingart, Yemisi Takwoingi

Faculty, Staff and Students Publications

Background: Xpert MTB/RIF Ultra (Xpert Ultra) is a molecular World Health Organization (WHO)-recommended rapid diagnostic test that simultaneously detects tuberculosis and rifampicin resistance. This review updates a comparative accuracy Cochrane review of Xpert MTB/RIF and Xpert Ultra as Xpert Ultra has replaced Xpert MTB/RIF.

Objectives: To determine the diagnostic accuracy of Xpert MTB/RIF Ultra (Xpert Ultra) for detecting pulmonary tuberculosis and rifampicin resistance in adults and adolescents with presumptive tuberculosis based on signs or symptoms or with an abnormal chest x-ray suggestive of tuberculosis.

Search methods: We searched seven databases including CENTRAL, MEDLINE, and Embase, plus two trial registers (ClinicalTrials.gov …


Effects Of The Gut Microbiota On Placental Angiogenesis And Intrauterine Growth In Gnotobiotic Mice, Reyan Coskun, Zenan L Chang, Athziri Marcial Rodríguez, Haoxin Liu, Jiye Cheng, Yael Alippe, Michael S Diamond, Jeffrey I Gordon Jul 2025

Effects Of The Gut Microbiota On Placental Angiogenesis And Intrauterine Growth In Gnotobiotic Mice, Reyan Coskun, Zenan L Chang, Athziri Marcial Rodríguez, Haoxin Liu, Jiye Cheng, Yael Alippe, Michael S Diamond, Jeffrey I Gordon

2020-Current year OA Pubs

Environmental causes of intrauterine growth restriction (IUGR) remain poorly characterized. Here, we compare germ-free (GF) and conventionally raised (CONV-R) mice to assess the effects of the gut microbiota on placental/fetal development at embryonic day (E)11.5 (end of placentation) and E17.5 (near term). Pregnancy- and microbiota-associated changes in gene expression occur along the gut, including those related to angiogenesis, while bacterial composition and fermentation activity remain stable. Placental weights at E11.5 and fetal weights at E17.5 are significantly reduced in GF animals. Compared to CONV-R dams, the GF maternal decidua exhibits similar vascular histomorphometric features at E11.5 and E17.5, and numbers …


Prevalence Of Stress Urinary Incontinence In Female Strength Athletes, Meghan Rohde, Jason Brumitt, Jodi Sandvik, Kari Bo Jul 2025

Prevalence Of Stress Urinary Incontinence In Female Strength Athletes, Meghan Rohde, Jason Brumitt, Jodi Sandvik, Kari Bo

Internet Journal of Allied Health Sciences and Practice

Background: Stress urinary incontinence (SUI) is a symptom during pregnancy and in the postpartum period, but a high prevalence of SUI is experienced in sports involving running and jumping. Objectives: Identify the scope of the problem of SUI in women participating in strength sports, movement patterns that elicit SUI, and the impact on quality of life in female athletes with SUI. Study Design: Survey mixed methods with qualitative focus groups. Methods: The International Consultation on Incontinence Questionnaire Short Form (ICIQ-SF) and a sport-specific and obstetric/gynecological history questionnaire were sent to women who are United States citizens, age 18-65, and …


Predictors Of Sleep Duration In Undergraduate Students Attending A Health Sciences University In Japan, Aaron M. Eakman, Yuki Kawakatsu, Miki Takahata, Daisuke Kudo, Shinji Satake, Toshiaki Sato Jul 2025

Predictors Of Sleep Duration In Undergraduate Students Attending A Health Sciences University In Japan, Aaron M. Eakman, Yuki Kawakatsu, Miki Takahata, Daisuke Kudo, Shinji Satake, Toshiaki Sato

Internet Journal of Allied Health Sciences and Practice

Background: Inadequate sleep is a pressing public health concern contributing to absenteeism and poor school performance, especially in health sciences students. In this study we investigated the sleep quality and duration of undergraduate students in a prefectural university of health sciences program and explored factors explaining sleep duration (i.e., < 6 hours per night vs > 6 hours) using multiple variable logistic regression.

Method: This cross-sectional survey study included 369 nursing, occupational therapy and physical therapy students who completed Japanese versions of the Pittsburg Sleep Quality Index, in addition to well validated sleep-related and mental health-related assessments.

Results: We found just 11.7% of the …


Navigating Cultural Barriers In Clinical Education: Unique Experiences And Insights From Culturally And Linguistically Diverse (Cald) Physiotherapy Students, Non-Cald Students, And Clinical Educators, Annie Yu, Neil Tuttle, Andrea Hams, Benjamin K. Weeks, Saras Henderson, Liisa Laakso Jul 2025

Navigating Cultural Barriers In Clinical Education: Unique Experiences And Insights From Culturally And Linguistically Diverse (Cald) Physiotherapy Students, Non-Cald Students, And Clinical Educators, Annie Yu, Neil Tuttle, Andrea Hams, Benjamin K. Weeks, Saras Henderson, Liisa Laakso

Internet Journal of Allied Health Sciences and Practice

Purpose: Culturally and Linguistically Diverse (CALD) students commonly face cultural barriers in the clinical learning environment that can impact on the success of clinical education experiences. Lack of effective strategies to facilitate clinical learning can be challenging for students and clinical educators alike. This study aimed to explore the issues impacting on clinical learning from the perspectives of CALD physiotherapy students and their clinical educators, and seeks suggestions from both participant groups to improve the clinical education experience. Methods: Qualitative descriptive design using grounded theory principles was utilised to gain insights from physiotherapy students and clinical educators regarding their clinical …


Transforming Healthcare Virtually: A Comprehensive Exploration Of Artificial Intelligence In Telehealth Across Internal Medicine Subspecialties, Jassimran Singh, Aditi Agrawal Jul 2025

Transforming Healthcare Virtually: A Comprehensive Exploration Of Artificial Intelligence In Telehealth Across Internal Medicine Subspecialties, Jassimran Singh, Aditi Agrawal

Internet Journal of Allied Health Sciences and Practice

This review provides a comprehensive exploration of the transformative role of artificial intelligence (AI) in revolutionizing telehealth within various subspecialties of internal medicine. The focus is on enhancing patient care, addressing healthcare challenges, and mitigating professional burnout through the real-time, data-driven insights offered by AI. The integration of AI in telehealth is examined across diverse medical fields such as cardiology, pulmonary medicine, gastroenterology, endocrinology, geriatrics, nephrology, neurology, and hematology-oncology. The research methodology employs a systematic literature review and analysis approach, utilizing academic databases such as PubMed, Scopus, and IEEE Xplore to identify relevant literature up to July 2023. Inclusion criteria …


A National Study Of Opioid Knowledge Of Physical Therapy Professionals, Shelene Thomas, John Kiesel, Steven G. Kinney, Isain Zapata Jul 2025

A National Study Of Opioid Knowledge Of Physical Therapy Professionals, Shelene Thomas, John Kiesel, Steven G. Kinney, Isain Zapata

Internet Journal of Allied Health Sciences and Practice

Purpose: Deaths from opioid overdoses persist as the leading preventable cause of death in the United States. Musculoskeletal pain remains the primary symptom for opioid prescription. Physical therapists (PTs) and physical therapy assistants (PTAs) provide non-prescription pain management strategies to people with musculoskeletal pain. Currently, there lacks research quantifying opioid overdose management knowledge possessed by PTs, PTAs, and their respective students. The purpose of this study was to quantify opioid overdose knowledge by PTs, PTAs, and their respective students, collectively termed physical therapy professionals (PTP). Methods: The electronic survey included several demographic characteristics and the opioid overdose knowledge scale (OOKS) …


Increasing Clinical Placements For Occupational Therapy In A Social Services Setting: Innovations For Practice, Martin Fitzgerald, Becky Antich, Ele Grimwood Jul 2025

Increasing Clinical Placements For Occupational Therapy In A Social Services Setting: Innovations For Practice, Martin Fitzgerald, Becky Antich, Ele Grimwood

Internet Journal of Allied Health Sciences and Practice

Purpose: The provision of undergraduate clinical placements to support Allied Health education has always been a challenge. However, in the last few years, the mismatch between undergraduate students and available placements has become acute. This paper describes how an undergraduate occupational therapy programme and a Metropolitan Council provider of social services worked together to overcome these challenges. The aim was to enhance inter-institutional cooperation and placement educator support and to increase placement opportunities. Method: A series of meetings between the university and the host institution identified barriers and opportunities to placement expansion. For the host institution, these included the absence …


Impact Of Self-Selected Self-Care Activities On Perceived Stress And Resilience Of Doctor Of Physical Therapy Students, Leslie F. Taylor, Niamh M. Tunney, Lisa Fraher Jul 2025

Impact Of Self-Selected Self-Care Activities On Perceived Stress And Resilience Of Doctor Of Physical Therapy Students, Leslie F. Taylor, Niamh M. Tunney, Lisa Fraher

Internet Journal of Allied Health Sciences and Practice

Purpose: To assess the impact of self-selected self-care activities, supported by four interspersed reflection prompts, on the perceived stress and resilience of Doctor of Physical Therapy (DPT) students over 12 weeks. Methods: This exploratory study used a convergent parallel mixed-methods design. Participants included third-semester DPT students (n=37; Class of 2024) enrolled in an eight-semester program.100% provided consent, with an 89% response rate (n=32). Quantitative pre- and post-measures included the Perceived Stress Scale (PSS), the Connor-Davidson Resilience Scale (CD RISC-25), and a researcher-developed survey which asked students to identify their current self-care activities from a list of physical, psychological, emotional, spiritual, …


Clinical Observation Of Oral-Motor Dysfunction In Joubert Syndrome: Case Series, Müberra Tanrıverdi, Gökhan Can Törpü Jul 2025

Clinical Observation Of Oral-Motor Dysfunction In Joubert Syndrome: Case Series, Müberra Tanrıverdi, Gökhan Can Törpü

Internet Journal of Allied Health Sciences and Practice

Purpose: Joubert Syndrome (JS) is a rare autosomal recessive neurological disorder, characterized by hypotonia, ataxia, tremor, developmental delay. JS also presents with respiratory abnormalities, oculomotor apraxia, motor speech dysarthria, and various atypical dysmorphic features. Oral-motor dysfunction (OMD) is a notable concern in JS, manifesting as difficulties with sucking, swallowing, drooling, and prolonged meal times. Methods: This study investigates OMD in five JS cases evaluated by physiotherapists and assessed using the Oral-Motor Examination Tool (OMET). Results: The cases exhibited feeding-related stress symptoms such as gagging and reflux. OMET evaluations identified asymmetrical faces, puckered lips, open mouths, and lip biting, with normal …


Conflict Between Student Physical Therapists And Clinical Instructors During Full-Time Clinical Education, Megan W. Moran Jul 2025

Conflict Between Student Physical Therapists And Clinical Instructors During Full-Time Clinical Education, Megan W. Moran

Internet Journal of Allied Health Sciences and Practice

Purpose: The purpose of this study was to determine what conflicts student physical therapists perceive with their clinical instructors during full-time clinical education experiences and if there was an association between conflict and the students’ opinions of their learning and the overall clinical education experience. Students in other healthcare disciplines experience conflict during clinical education. Additionally, research shows that licensed healthcare providers report conflict in the workplace. These conflicts can result in positive and negative consequences for the learner or provider and the patients. Tailored training may help to minimize the negative consequences; however, there is a lack of available …


Educational Objectives Of Doctor Of Athletic Training (Dat) Degree Programs: A Document Review, Matthew J. Rivera, Samuel Orr, Lindsey E. Eberman Jul 2025

Educational Objectives Of Doctor Of Athletic Training (Dat) Degree Programs: A Document Review, Matthew J. Rivera, Samuel Orr, Lindsey E. Eberman

Internet Journal of Allied Health Sciences and Practice

Purpose: The Doctor of Athletic Training (DAT) degree is one postprofessional educational pathway that could provide athletic trainers advancement in clinical, leadership, and scholarship practice. Although some is known about the motivations to pursue and the anticipated learning outcomes from both clinical and educational settings, we sought to explore the stated learning outcomes DAT programs publicly state related to advanced clinical practice, advanced practice leadership, scholarship, and specific programmatic uniqueness. Methods: We used a document review of publicly available websites. We analyzed eight DAT program websites that were available as of September 2023. Using deductive coding, from the professional …


Analysis Of Ringside Physician Stoppages In Professional Mixed Martial Arts., Andy Suarez, Justin Braun, Corey Peacock, Gabriel J. Sanders Jul 2025

Analysis Of Ringside Physician Stoppages In Professional Mixed Martial Arts., Andy Suarez, Justin Braun, Corey Peacock, Gabriel J. Sanders

Internet Journal of Allied Health Sciences and Practice

Modern Mixed Martial Arts (MMA), popularized globally by the Ultimate Fighting Championship (UFC) since 1993, initially faced significant concerns regarding fighter safety but improved considerably following the introduction of comprehensive regulatory measures. Despite these enhancements, MMA continues to carry substantial risk, particularly evident in bouts concluded by referee or medical stoppages. These stoppages are critical safety mechanisms protecting fighters and providing valuable insights into injury trends. This study specifically investigates MMA bouts stopped by ringside physicians due to medical concerns or observed injuries, emphasizing potential differences in these stoppages between male and female fighters. The methods involved the analysis of …


Respiratory Syncytial Virus, Tahani Ali Alshammari, Ali Mohi Alqahtani Jul 2025

Respiratory Syncytial Virus, Tahani Ali Alshammari, Ali Mohi Alqahtani

Internet Journal of Allied Health Sciences and Practice

Abstract:

Respiratory Syncytial Virus (RSV) is a highly contagious pathogen causing significant respiratory infections across all age groups, with heightened severity in infants and the elderly. This paper provides a comprehensive overview of the virus's epidemiology, the associated dangers, and current therapeutic interventions. Historical data identifies RSV as a primary cause of respiratory hospitalizations in infants and ageing populations, with reinfection common throughout life. After several trials and molecular diagnostics to find treatment options, various vaccines, antiviral drugs, and monoclonal antibodies have been licensed for use in various parts of the world. Recent studies explore the importance of passive immunization …


Evaluating Assistive Technologies In High Acuity Patients: A Scoping Review With Swot Analysis, Mallory Kargela Pt, Dpt, Amanda Anderson Pt, Dpt, Lindsay Anderson Pt, Dpt, Tian Gong Pt, Dpt, Kylie Scott Pt, Dpt, Edd Jul 2025

Evaluating Assistive Technologies In High Acuity Patients: A Scoping Review With Swot Analysis, Mallory Kargela Pt, Dpt, Amanda Anderson Pt, Dpt, Lindsay Anderson Pt, Dpt, Tian Gong Pt, Dpt, Kylie Scott Pt, Dpt, Edd

Internet Journal of Allied Health Sciences and Practice

Purpose: This publication examines the application of assistive technologies (AT) in high-acuity environments, including intensive care units (ICUs), acute care hospitals, and others. The aim is to systematically explore and synthesize the use of AT across these settings, identifying key strengths, weaknesses, opportunities, and threats (SWOT) associated. Methods: A literature search was conducted from 2016 to 2023 using PubMed, Tufts and Midwestern University Library databases. Search terms included ('physical therapy' OR 'physiotherapy') AND ('critically ill' OR 'acute' OR 'intensive care') AND ('assistive technology' OR 'technology' OR 'telerehabilitation' OR 'telePT' OR 'functional electrical stimulation' OR 'FES' OR 'cycle ergometry' …


Barriers And Facilitators To Occupational Therapy For The Frail Older Person Within Primary Care In Belgium, Anne Ledoux, Stijn De Baets, Thérèse Van Durme, Patricia De Vriendt, Dominique Van De Velde, Sophie Thunus Jul 2025

Barriers And Facilitators To Occupational Therapy For The Frail Older Person Within Primary Care In Belgium, Anne Ledoux, Stijn De Baets, Thérèse Van Durme, Patricia De Vriendt, Dominique Van De Velde, Sophie Thunus

Internet Journal of Allied Health Sciences and Practice

Introduction: The population is quickly aging in Belgium and there is an increasing number of older frail adults. Occupational therapy (OT) in primary care (PC) favors the stay-at-home of frail older persons through its preventive action on the person, the environment, and/or the task. However, OT is not well implemented in Belgian PC. We aimed to investigate the implementation of OT, to support the frail older person living at home, within primary care in Belgium. Methods: We performed a secondary thematic analysis, based on data collected during an implementation study of an OT guideline for this population. Data were collected …


Do Gender-Related Characteristics Impact Female Faculty Career Progression In Academic Doctor Of Physical Therapy Programs?, Bridget Eubanks Jul 2025

Do Gender-Related Characteristics Impact Female Faculty Career Progression In Academic Doctor Of Physical Therapy Programs?, Bridget Eubanks

Internet Journal of Allied Health Sciences and Practice

Purpose: This study explored the experiences of female faculty in academic Doctor of Physical Therapy (DPT) programs in the US and if gender, or more specifically any gender-related characteristics such as pregnancy or motherhood, impacts female faculty career progression. Evidence has demonstrated that several challenges disproportionately affect women in academia, but there is currently no research available related to female faculty experiences in academic DPT programs. Methods: This study used a qualitative research design with a descriptive statistics component. It utilized a descriptive, cross-sectional design with a nonexperimental survey methodology. The Culture Conducive to Women’s Academic Success instrument was used …


Defining And Addressing Student Unprofessional Behaviors From The Physical Therapy Clinical Instructors’ Perspective, Michele "Shelly" Lewis, Nicole Biltz, Moyo B. Tillery, Jamie Dunlap Coates, Tracy Ellison, Elsa M. Drevyn Jul 2025

Defining And Addressing Student Unprofessional Behaviors From The Physical Therapy Clinical Instructors’ Perspective, Michele "Shelly" Lewis, Nicole Biltz, Moyo B. Tillery, Jamie Dunlap Coates, Tracy Ellison, Elsa M. Drevyn

Internet Journal of Allied Health Sciences and Practice

Purpose: Developing professional behaviors is an integral part of health professional education. Despite physical therapy education programs’ efforts to assist student physical therapists in developing professional behaviors before entering the clinic, some students still struggle with professional behaviors during clinical education experiences. Literature describing unprofessional behaviors in the clinic and providing guidance for clinical instructors to assess and address professional behavior issues is scarce. This study was conducted to investigate the type of unprofessional behaviors student physical therapists display during clinical education experiences and to describe successful and unsuccessful strategies used by clinical instructors to address challenging behaviors. Method: A …


14-Year Retrospective Review Of Audiology Graduate Admission Data: Comparative Analysis With Other First Professional Health Programs, Alyssa R. Needleman, Patricia A. Gaffney, Erica B. Friedland, Josiah Alamu Jul 2025

14-Year Retrospective Review Of Audiology Graduate Admission Data: Comparative Analysis With Other First Professional Health Programs, Alyssa R. Needleman, Patricia A. Gaffney, Erica B. Friedland, Josiah Alamu

Internet Journal of Allied Health Sciences and Practice

Purpose: Demographic and cognitive data on students entering audiology programs is incomplete, and there is a lack of comparison among audiology students and those entering other first professional health (FPH) programs. This paper is the first of a multi-part series to provide evidence into the characteristics of the typical audiology student and their graduate outcomes. This is valuable for improving recruiting, admissions, retention, and success rates of audiology programs. A comprehensive descriptive analysis of admission criteria was performed for students who entered the NSU Doctor of Audiology (AuD) program over the last 14 years. Additionally, NSU admissions data was compared …