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Articles 156301 - 156330 of 325328
Full-Text Articles in Medicine and Health Sciences
Smokeless Tobacco Use And Risk Of Oral Cavity Cancer, Shah Zeb Khan, Ahmed Farooq, Misbah Masood, Abubaker Shahid, Irfan Ullah Khan, Hasan Nisar, Ismat Fatima
Smokeless Tobacco Use And Risk Of Oral Cavity Cancer, Shah Zeb Khan, Ahmed Farooq, Misbah Masood, Abubaker Shahid, Irfan Ullah Khan, Hasan Nisar, Ismat Fatima
Turkish Journal of Medical Sciences
Background/aim: Smokeless tobacco has been associated with oral cavity cancer for several decades. The incidence of oral cavity cancer is higher in some parts of the world especially South and South-East Asia including Pakistan. The aim of current study was to evaluate the risk of oral cavity cancer among smokeless tobacco users in our country. Materials and methods: A case-control study was conducted between November 2016 and September 2017. Patients diagnosed with oral cavity cancer receiving treatment were included as cases and the attendants of various cancer patients visiting the hospital during the study period were included in the study …
Adiponectin Levels Decrease Independently Of Body Mass Index And Diabetes Type Afterthe Normalization Of Hyperglycemia, Nalan Meti̇n Aksu, Duygu Yazgan Aksoy, Meltem Akkaş, Neşe Çinar, Fatma Uçar, Okan Bülent Yildiz, Aydan Usman
Adiponectin Levels Decrease Independently Of Body Mass Index And Diabetes Type Afterthe Normalization Of Hyperglycemia, Nalan Meti̇n Aksu, Duygu Yazgan Aksoy, Meltem Akkaş, Neşe Çinar, Fatma Uçar, Okan Bülent Yildiz, Aydan Usman
Turkish Journal of Medical Sciences
Background/aim: Acute hyperglycemia is generally a frequently encountered condition in the emergency department (ED), because it is seen as a complication of diabetes mellitus (DM). In this study, we aimed to detect the change in adiponectin levels during acute hyperglycemic states and after normalization of blood glucose with insulin treatment. Materials and methods: Forty-eight patients over the age of 18 years who were admitted to the ED with acute hyperglycemia were included in the study. Serum samples were taken from patients on admission and 6 h after the normalization of blood glucose with insulin treatment, and adiponectin levels were measured …
Midkine Level May Be Used As A Noninvasive Biomarker In Crohn's Disease, Murat Keki̇lli̇, Alpaslan Tanoğlu, Fati̇h Karaahmet, Zeynal Doğan, Murat Can, Abdurrahi̇m Sayilir, Başak Çakal, Tolga Düzenli̇, Yavuz Beyazi̇t
Midkine Level May Be Used As A Noninvasive Biomarker In Crohn's Disease, Murat Keki̇lli̇, Alpaslan Tanoğlu, Fati̇h Karaahmet, Zeynal Doğan, Murat Can, Abdurrahi̇m Sayilir, Başak Çakal, Tolga Düzenli̇, Yavuz Beyazi̇t
Turkish Journal of Medical Sciences
Background/aim: Crohn's disease (CD) is a kind of inflammatory bowel disease. Midkine (MDK) is an endogenous inflammatory marker. We aimed to investigate the relationship between MDK levels and inflammation and hence determine whether MDK can be used as a noninvasive biomarker in active CD. Materials and methods: Sixty-five consecutive patients over the age of 18 with CD and 36 healthy controls were included in this study. CD patients' venous blood samples were taken before treatment. Serum MDK levels were determined in human plasma samples by enzyme-linked immunosorbent assay (ELISA) method. Results: The mean age of the study patients was 44.8 …
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Correlation Of Serum Fatty Acid Binding Protein-4 And Interleukin-6 With Airflowlimitation And Quality Of Life In Stable And Acute Exacerbation Of Copd, Mohammad Reza Aslani, Zeynab Ghazaei, Hassan Ghobadi
Turkish Journal of Medical Sciences
Background/aim: The serum fatty acid binding protein 4 (FABP-4) level increases in chronic inflammatory diseases. The present study aimed to examine serum FABP-4 and interleukin (IL)-6 levels in patients with stable and acute exacerbation of chronic obstructive pulmonary disease (COPD) and the correlation of these markers with airflow limitation. Materials and methods: We measured serum FABP-4 and IL-6 levels in 60 COPD patients [30 stable COPD (SCOPD), and 30 acute exacerbation of COPD (AECOPD)], and 30 healthy subjects and compared them with airflow limitation according to the COPD stage in the Global Initiative for Chronic Obstructive Pulmonary Disease (GOLD) criteria, …
Effect Of Sevoflurane Anaesthesia On Nasal Mask In Endoscopic Retrogradecholangiopancreatography: Is It A Preferred Alternative?, Bülent Baltaci, Hülya Başar, Murat Keki̇lli̇, Mert Naki̇p, Fati̇h Karaahmet, Mehmet Çakirca, Meli̇s Engi̇n, Meltem Bektaş
Effect Of Sevoflurane Anaesthesia On Nasal Mask In Endoscopic Retrogradecholangiopancreatography: Is It A Preferred Alternative?, Bülent Baltaci, Hülya Başar, Murat Keki̇lli̇, Mert Naki̇p, Fati̇h Karaahmet, Mehmet Çakirca, Meli̇s Engi̇n, Meltem Bektaş
Turkish Journal of Medical Sciences
Background/aim: Endoscopic retrograde cholangiopancreatography (ERCP) often requires deep sedation. Propofol provides adequate sedation and amnesia at subhypnotic doses, but safe guarding the patient's airway is important for preventing respiratory depression or hypoxic events. This study compared sedation levels, operator satisfaction, intraoperative and recovery characteristics using sevoflurane with nasal mask and propofol in ERCP. Material and methods: Sixty-one patients underwent ERCP (Group I: propofol, n = 31; Group II, sevoflurane, n = 30), with sedation controlled by the Ramsay sedation scale (RSS). The patients' demographic data, procedure length, overall drug dose, hemodynamic changes, duration of recovery and Aldrete scores during recovery …
Tumour Budding In Preoperative Biopsy Specimens Is A Useful Prognostic Index Foridentifying High-Risk Patients In Early-Stage (Pn0) Colon Cancer, Mehmet Zengi̇n, Aydin Çi̇fci̇
Tumour Budding In Preoperative Biopsy Specimens Is A Useful Prognostic Index Foridentifying High-Risk Patients In Early-Stage (Pn0) Colon Cancer, Mehmet Zengi̇n, Aydin Çi̇fci̇
Turkish Journal of Medical Sciences
Background/aim: Tumour budding (BD) is considered a valuable prognostic factor in colon cancer (CC), but its use in daily practice is uncertain. We investigated the prognostic effect of BD using preoperative biopsy specimens in a fairly homogeneous population. Materials and methods: Eighty-two (pN0) CC patients who underwent surgery after preoperative biopsy between 1997 and 2013 were included in the study. Model A (using the `deeply invasive blocks & hot-spot area & invasive margin) and method 1 (using the `20× objective & immunohistochemistry staining & quantitive counting') were used as standard methods. Results: High BD was significantly associated with poor prognostic …
The Use Of Prealbumin As A Predictor Of Malnutrition In Cirrhotic Patients And The Effectof Nutritional Support In Patients With Low Prealbumin Levels, Zuhal Dağ, Hüseyi̇n Köseoğlu, Murat Keki̇lli̇
The Use Of Prealbumin As A Predictor Of Malnutrition In Cirrhotic Patients And The Effectof Nutritional Support In Patients With Low Prealbumin Levels, Zuhal Dağ, Hüseyi̇n Köseoğlu, Murat Keki̇lli̇
Turkish Journal of Medical Sciences
Background/aim: Malnutrition is an important and commonly seen prognostic factor in patients with cirrhosis. The diagnosis of malnutrition in cirrhosis patients may be challenging, and an easily measured and widely usable marker is lacking. Prealbumin, however, is an easily measured marker. In the current study we measured prealbumin levels in cirrhotic patients with no clinically apparent malnutrition and used it as a malnutrition marker. Another aim of this study was to evaluate the effect of nutritional support on patient with low prealbumin levels. Materials and methods: Fifty-two patients with Child A and Child B cirrhosis were selected for the study. …
Somatic Regional Oxygen Saturation As An Early Marker Of Intra-Abdominal Hypertensionin Critically Ill Children: A Pilot Study, Özden Özgür Horoz, Vahi̇de Nagehan Aslan, Riza Di̇nçer Yildizdaş, Yasemi̇n Çoban, Yaşar Sertdemi̇r, Awni Al-Subu
Somatic Regional Oxygen Saturation As An Early Marker Of Intra-Abdominal Hypertensionin Critically Ill Children: A Pilot Study, Özden Özgür Horoz, Vahi̇de Nagehan Aslan, Riza Di̇nçer Yildizdaş, Yasemi̇n Çoban, Yaşar Sertdemi̇r, Awni Al-Subu
Turkish Journal of Medical Sciences
Background/aim: Intraabdominal hypertension is a common clinical condition with high mortality and morbidity in pediatric intensive care units. The aim of this study was to test the feasibility of regional tissue oxygenation (rSO2 ) measurement using nearinfrared spectroscopy and to assess the correlation between rSO2 and perfusion markers of intraabdominal hypertension in high-risk pediatric patients. Materials and methods: In this prospective observational cohort study in a tertiary pediatric intensive care unit in Çukurova University Faculty of Medicine, a total of 31 patients who were admitted between May 2017 and May 2018 with a risk of intraabdominal hypertension were included. Mesenteric …
What Is The Effect Of The Early Follicular Phase Fsh/Lh Ratio On The Number Of Matureoocytes And Embryo Development?, Özgür Arat, Şükri̇ye Derya Deveci̇, Zehra Sema Özkan, Sevi̇m Tuncer Can
What Is The Effect Of The Early Follicular Phase Fsh/Lh Ratio On The Number Of Matureoocytes And Embryo Development?, Özgür Arat, Şükri̇ye Derya Deveci̇, Zehra Sema Özkan, Sevi̇m Tuncer Can
Turkish Journal of Medical Sciences
Background/aim: Basal level of follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol (E2), and antral follicle count are used as predictors of ovarian reserve before starting ovulation induction. We aimed to investigate the predictor potential of early follicular phase FSH/LH ratio on controlled ovarian hyperstimulation-intracytoplasmic sperm injection (COH-ICSI) cycle outcomes. Materials and methods: This retrospective cohort study was conducted with 648 COH-ICSI cycles performed between 2012 and 2014. Cycles were classified according to their basal FSH/LH ratio, group 1(G1) = FSH/LH ratio < 2, N = 473 and group 2(G2) = FSH/LH ratio ∠ 2, N = 175. Demographic characteristics and stimulation parameters were evaluated. Retrieved total oocyte count (TOC), mature oocyte count (MOC), transferred embryo number, and pregnancy results were obtained and transferred to computer by SPSS 21.0 programme. Results: TOC and MOC of G1 were significantly higher than those of G2. The total gonadotrophin doses of G2 were significantly higher than G1. There was no significant difference between groups for transferred embryo number. Pregnancy and live birth rates were similar in both groups. Conclusion: In our population, increased FSH/LH ratio did not affect the rates of pregnancy and live birth negatively.
Shearwave Elastographic Evaluation Of Uterine Leiomyomas After Uterine Arteryembolization: Preliminary Results, Cesur Samanci, Yilmaz Önal
Shearwave Elastographic Evaluation Of Uterine Leiomyomas After Uterine Arteryembolization: Preliminary Results, Cesur Samanci, Yilmaz Önal
Turkish Journal of Medical Sciences
Background/aim: We aimed to investigate the role of Shearwave Elastography (SWE) in the evaluation of response to uterine artery embolization (UAE) in patients with uterine leiomyomas. Materials and methods: SWE images of the dominant uterin leiomyomas were obtained before and 1.5 months after performing UAE in 33 women suffering from symptoms due to leiomyomas (menometrorrhagia, bulk related symptoms, pelvic pain). Leiomyomas were also evaluated by 2 observers for location and longest diameter in axial plane. Interobserver agreement in the quantitative SWE analysis was calculated using intraclass correlation coefficients. Results: Thirty-three women (mean age, 39.7 years; range, 31-48 years) were examined …
Efficacy Of Mepolizumab Treatment In Oral Corticosteroid-Dependent Severe Eosinophilicasthma Patients With Chronic Rhinosinusitis With Nasal Polyps: Single Center, Real Life Study, İnsu Yilmaz, Murat Türk, Saki̇ne Nazi̇k Bahçeci̇oğlu, Nuri̇ Tutar, İnci̇ Gülmez
Efficacy Of Mepolizumab Treatment In Oral Corticosteroid-Dependent Severe Eosinophilicasthma Patients With Chronic Rhinosinusitis With Nasal Polyps: Single Center, Real Life Study, İnsu Yilmaz, Murat Türk, Saki̇ne Nazi̇k Bahçeci̇oğlu, Nuri̇ Tutar, İnci̇ Gülmez
Turkish Journal of Medical Sciences
Background/aim: Oral corticosteroid (OCS)-dependent severe eosinophilic asthma with chronic rhinosinusitis with nasal polyps (SEACRSwNP) would be a suitable phenotype for mepolizumab treatment. This study evaluated the short-term efficacy of mepolizumab treatment in OCS-dependent SEA-CRSwNP. Materials and methods: Baseline and 24th week results [daily OCS doses, asthma exacerbation frequency, asthma control test (ACT) scores, blood eosinophil levels, FEV1 values, and numerical analog scale (NAS) of CRSwNP symptoms] of patients who were treated for at least 24 weeks with mepolizumab were retrospectively evaluated and compared. Results: A total of 16 patients were enrolled in the study. Mepolizumab was discontinued in one patient …
The In Vitro Cytotoxic, Genotoxic, And Oxidative Damage Potentials Of The Oral Artificialsweetener Aspartame On Cultured Human Blood Cells, Kenan Çadirci, Özlem Özdemi̇r Tozlu, Hasan Türkez, Adi̇l Mardi̇noğlu
The In Vitro Cytotoxic, Genotoxic, And Oxidative Damage Potentials Of The Oral Artificialsweetener Aspartame On Cultured Human Blood Cells, Kenan Çadirci, Özlem Özdemi̇r Tozlu, Hasan Türkez, Adi̇l Mardi̇noğlu
Turkish Journal of Medical Sciences
Background/aim: Aspartame (APM, L-aspartyl-L-phenylalanine methylester) is a low-calorie, nonsaccharide artificial sweetener widely used in foods and beverages. When metabolized by the body, APM is broken down into aspartic acid, phenylalanine amino acids, and a third substance, methanol. Since the amino acid phenylalanine serves as a neurotransmitter building block affecting the brain, and methanol is converted into toxic formaldehyde, APM has deleterious effects on the body and brain. Thus, its safety and, toxicity have been the subjects of concern ever since it was first discovered. Although many studies have been performed on it, due to the presence of conflicting data in …
Effect Of Metformin And Detorsion Treatment On Serum Anti-Müllerian Hormonelevels And Ovarian Histopathology In A Rat Ovarian Torsion Model, Sema Karakaş, Ci̇han Kaya, Hakan Güraslan, Damlanur Sakiz, Sema Süzen Çaypinar, Hüseyi̇n Cengi̇z, Murat Eki̇n, Levent Yaşar
Effect Of Metformin And Detorsion Treatment On Serum Anti-Müllerian Hormonelevels And Ovarian Histopathology In A Rat Ovarian Torsion Model, Sema Karakaş, Ci̇han Kaya, Hakan Güraslan, Damlanur Sakiz, Sema Süzen Çaypinar, Hüseyi̇n Cengi̇z, Murat Eki̇n, Levent Yaşar
Turkish Journal of Medical Sciences
Background/aim: Adnexal torsion is a common gynaecological emergency, and considered to be a problem mostly in reproductive-age women. To evaluate the effect of metformin and detorsion treatment on reducing ovarian reserve in an ovarian torsion model. Materials and methods: Twenty-four nonpregnant, Wistar Hannover rats were included in the study. Animals were divided into 3 groups: the control group, the detorsion only group, and the metformin + detorsion group. The first group received only laparotomy. In the second group, ovaries were fixed to the abdominal wall after performing 360° ovarian torsion, followed by detorsion after a 3-h period of ischemia. The …
Reliability And Validity Of The Turkish Version Of The Diabetes Distress Scale For Type 2diabetes And Distress Levels Of The Participants, Özge Telci̇ Çaklili, Güneş Feyi̇zoğlu, Selcan Tülü Çolak, Nazli Di̇zman, Sidika İrem Bozkurt Çakir, Ayteki̇n Oğuz
Reliability And Validity Of The Turkish Version Of The Diabetes Distress Scale For Type 2diabetes And Distress Levels Of The Participants, Özge Telci̇ Çaklili, Güneş Feyi̇zoğlu, Selcan Tülü Çolak, Nazli Di̇zman, Sidika İrem Bozkurt Çakir, Ayteki̇n Oğuz
Turkish Journal of Medical Sciences
Background/aim: Studies have shown an increased depression rate in patients with type 2 diabetes mellitus (T2DM) compared to the normal population. It is now acknowledged that patients suffer from distress rather than depression. Our aim was to validate the Turkish version of the Diabetes Distress Scale (DDS) and to show distress levels of the participants. Materials and methods: The scale was translated from English to Turkish by the authors and translated back to English. Between August 2015 and January 2016 all the patients who were referred to the T2DM Clinic of İstanbul Medeniyet University were screened, and eligible patients were …
The Validity And Reliability Of The Turkish Version Of The Body Esteem Scale Foradolescents And Adults (Besaa) For Children, Umut Ece Arslan, Lütfi̇ye Hi̇lal Özcebe, Hande Konşuk Ünlü, Sarp Üner, Mahmut Saadi̇ Yardim, Ozgur Araz, Terry T-K Huang
The Validity And Reliability Of The Turkish Version Of The Body Esteem Scale Foradolescents And Adults (Besaa) For Children, Umut Ece Arslan, Lütfi̇ye Hi̇lal Özcebe, Hande Konşuk Ünlü, Sarp Üner, Mahmut Saadi̇ Yardim, Ozgur Araz, Terry T-K Huang
Turkish Journal of Medical Sciences
Background/aim: Body esteem (BE) is defined as the self-evaluation of one's own body or appearance. The Body Esteem Scale for Adolescents and Adults (BESAA) consists of three subscales: BE-appearance, BE-weight, and BE-attribution. Though initially developed for adolescents and adults, the use of the scale has recently increased in health-related research on children. This study aimed to assess the validity and reliability of the Turkish version of the BESAA for children. Materials and methods: The participants in the study were 4th grade children (aged 9-10 years) in Ankara, Turkey. The validity of the scale was evaluated through exploratory and confirmatory factor …
Validation Of The Turkish Version Of The Sunnybrook Facial Grading System, Erdem Mengi̇, Cüneyt Orhan Kara, Fazil Necdet Ardiç, Funda Tümkaya, Fevzi̇ Barlay, Taylan Çi̇l, Hande Şenol
Validation Of The Turkish Version Of The Sunnybrook Facial Grading System, Erdem Mengi̇, Cüneyt Orhan Kara, Fazil Necdet Ardiç, Funda Tümkaya, Fevzi̇ Barlay, Taylan Çi̇l, Hande Şenol
Turkish Journal of Medical Sciences
Background/aim: To adapt the Sunnybrook facial grading system (SFGS) into Turkish and perform validation and reliability studies on the Turkish version. Materials and Methods: The original English version of the SFGS was translated into Turkish by performing a linguistic validity study based on international standards. The evaluators comprised 6 physicians. Evaluations were performed twice independently using the video recordings of 65 facial palsy patients. Synchronously, the House-Brackman facial grading system (HBFGS) was filled out to display concurrent validity. The intraclass correlation coefficient (ICC) and Cronbach's alpha was used for the examination of the inter- and intra-rater reliability. As another indication …
The Effects Of Blood Group Types On The Risk Of Covid-19 Infection And Its Clinical Outcome, Hakan Göker, Eli̇fcan Aladağ Karakulak, Haluk Demi̇roğlu, Çağlayan Merve Ayaz Ceylan, Yahya Büyükaşik, Ahmet Çağkan İnkaya, Salih Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu, Ömrüm Uzun, Murat Akova, Osman İlhami̇ Özcebe, Serhat Ünal
The Effects Of Blood Group Types On The Risk Of Covid-19 Infection And Its Clinical Outcome, Hakan Göker, Eli̇fcan Aladağ Karakulak, Haluk Demi̇roğlu, Çağlayan Merve Ayaz Ceylan, Yahya Büyükaşik, Ahmet Çağkan İnkaya, Salih Aksu, Ni̇lgün Sayinalp, İbrahi̇m Celaletti̇n Haznedaroğlu, Ömrüm Uzun, Murat Akova, Osman İlhami̇ Özcebe, Serhat Ünal
Turkish Journal of Medical Sciences
Background/aim: COVID-19 (Coronavirus disease of 2019) is an infectious disease outbreak later on declared as a pandemic, caused by the SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2). It spreads very rapidly and can result in severe acute respiratory failure. The clinical studies have shown that advanced age and chronic diseases increase the risk of infection. However, influence of the blood groups on COVID-19 infection and its outcome remains to be confirmed. The aim of this study is to investigate whether there exists a relationship between the blood groups of the patients and risk of SARS-CoV-2 infection and the clinical outcomes in …
Is There Relationship Between Sars-Cov-2 And The Complement C3 And C4?, Hamad Dhei̇r, Savaş Si̇pahi̇, Selçuk Yaylaci, Mehmet Köroğlu, Ali̇ Fuat Erdem, Oğuz Karabay
Is There Relationship Between Sars-Cov-2 And The Complement C3 And C4?, Hamad Dhei̇r, Savaş Si̇pahi̇, Selçuk Yaylaci, Mehmet Köroğlu, Ali̇ Fuat Erdem, Oğuz Karabay
Turkish Journal of Medical Sciences
No abstract provided.
Real-Life Comparison Of The Viewing Angle And The Image Quality Of Two Commonly Usedviewing Systems For Vitreoretinal Surgery, Kemal Bayrakçeken, Ahmet Murad Hondur, Hati̇ce Tuba Atalay, Yavuz Kemal Aribaş
Real-Life Comparison Of The Viewing Angle And The Image Quality Of Two Commonly Usedviewing Systems For Vitreoretinal Surgery, Kemal Bayrakçeken, Ahmet Murad Hondur, Hati̇ce Tuba Atalay, Yavuz Kemal Aribaş
Turkish Journal of Medical Sciences
Background/aim: To compare the clinical use, image quality and viewing angle of a commonly used contact wide angle viewing (WAV) system (Advanced Visual Instruments (AVI) Panoramic Imaging Systems, NY, USA) with a commonly used noncontact WAV system (Leica RUV800, Leica Microsystems, Switzerland). Materials and methods: Images of 42 consecutively operated eyes were obtained with both systems at the same surgical stages and were compared for image quality using the Imatest Master 4.5.13 (Imatest LLC, Boulder, USA) software. The viewing angles of the images were calculated using the optic disc sizes measured from the OCT and infrared fundus images. The 68-degree …
Correlation Between The Glasgow-Blatchford Score, Shock Index, And Forrestclassification In Patients With Peptic Ulcer Bleeding, Hong Yang, Chen Pan, Qi Liu, Yan Wang, Zhe Liu, Xian Cao, Jingjing Lei
Correlation Between The Glasgow-Blatchford Score, Shock Index, And Forrestclassification In Patients With Peptic Ulcer Bleeding, Hong Yang, Chen Pan, Qi Liu, Yan Wang, Zhe Liu, Xian Cao, Jingjing Lei
Turkish Journal of Medical Sciences
Background/aim: To investigate the correlation between the Glasgow-Blatchford score, shock index, and Forrest classification in patients with peptic ulcer bleeding (PUB). Materials and methods: A total of 955 patients with PUB were assessed using the Glasgow-Blatchford score and shock index, as well as the Forrest classification based on their gastroscopy results. The correlation between the Glasgow-Blatchford score and shock index was determined using scatter plot analysis, and the correlation between the Glasgow-Blatchford score or shock index and Forrest classification was determined using Spearman's analysis. Results: Both the Glasgow-Blatchford score and shock index showed the highest values in patients with Forrest …
Clinical Characteristics And Long-Term Outcome Of Takayasu Arteritisin Iran: A Multicentre Study, Aida Malek Mahdavi, Nadereh Rashtchizadeh, Hadiseh Kavandi, Mehrzad Hajialilo, Sousan Kolahi, Mohammad-Reza Nakhjavani, Ali-Asghar Ebrahimi, Seyedmostafa Seyedmardani, Mansour Salesi, Mohsen Soroush, Alireza Khabbazi
Clinical Characteristics And Long-Term Outcome Of Takayasu Arteritisin Iran: A Multicentre Study, Aida Malek Mahdavi, Nadereh Rashtchizadeh, Hadiseh Kavandi, Mehrzad Hajialilo, Sousan Kolahi, Mohammad-Reza Nakhjavani, Ali-Asghar Ebrahimi, Seyedmostafa Seyedmardani, Mansour Salesi, Mohsen Soroush, Alireza Khabbazi
Turkish Journal of Medical Sciences
Background/aim: This study aimed to evaluate the demographic, clinical, angiographic and prognostic characteristics of Takayasu arteritis (TA) in Iran. Materials and methods: A total of 75 patients with TA based on the American College of Rheumatology 1990 criteria for TA classification referred to the Rheumatology Centres, were followed-up from 1989 to 2019. Demographic, clinical, angiographic and prognostic characteristics were collected at baseline and last visit. Results: The mean age was 31.9 ± 9.8 years at the disease onset. Female to male ratio was 14. The median latency in diagnosis was 24 months. Pulse discrepancy in the arms, blood pressure discrepancy …
The Antibiotic Prescribing Behaviors Of Physicians Are Changed Via Rapid Antigen Testpractice In The Context Of Rational Drug Use, Deni̇z Uzun, Hali̇l Kara, Muhammed Fati̇h Doğan, Seyfullah Oktay Arslan
The Antibiotic Prescribing Behaviors Of Physicians Are Changed Via Rapid Antigen Testpractice In The Context Of Rational Drug Use, Deni̇z Uzun, Hali̇l Kara, Muhammed Fati̇h Doğan, Seyfullah Oktay Arslan
Turkish Journal of Medical Sciences
Background/aim: Rapid antigen test (RAT) is a practical test to detect the presence of Group A beta hemolytic streptococcus antigens in throat swab samples. The aim of this study is to investigate the changes in the empiric antibiotic prescribing behavior of 10 family physicians in Kırıkkale Province after using RAT in 2017. Materials and methods: RAT test practice started in Family Medicine in February 2017. Family Medicine Information System (FMIS) includes clinical and prescription records of 10 family physicians, providing health service to approximately 35,000 residents in Kırıkkale. The numbers of antibiotics prescribed by the physicians according to the ICD-10 …
Evaluation Of Brain Fdg Pet Images In Temporal Lobe Epilepsy For Lateralization Ofepileptogenic Focus Using Data Mining Methods, Ümi̇t Özgür Akdemi̇r, İrem Çapraz, Seda Gülbahar Ateş, Keri̇m Şeker, Uğuray Aydos, Gökhan Kurt, Neşe Karabacak, Lütfi̇ye Özlem Atay, Erhan Bi̇li̇r
Evaluation Of Brain Fdg Pet Images In Temporal Lobe Epilepsy For Lateralization Ofepileptogenic Focus Using Data Mining Methods, Ümi̇t Özgür Akdemi̇r, İrem Çapraz, Seda Gülbahar Ateş, Keri̇m Şeker, Uğuray Aydos, Gökhan Kurt, Neşe Karabacak, Lütfi̇ye Özlem Atay, Erhan Bi̇li̇r
Turkish Journal of Medical Sciences
Background/aim: In temporal lobe epilepsy (TLE), brain positron emission tomography (PET) performed with F-18 fluorodeoxyglucose (FDG) is commonly used for lateralization of the epileptogenic temporal lobe. In this study, we aimed to evaluate the success of quantitative analysis of brain FDG PET images using data mining methods in the lateralization of the epileptogenic temporal lobe. Materials and methods: Presurgical interictal brain FDG PET images of 49 adult mesial TLE patients with a minimum of 2 years of postsurgical follow-up and Engel I outcomes were retrospectively analyzed. Asymmetry indices were calculated from PET images from the mesial temporal lobe and its …
The Effect Of Vitamin D Status On Different Neuromuscular Blocker Agents Reverse Time, İlknur Sui̇di̇ye Yorulmaz, Yavuz Demi̇raran, Onur Özlü, Burhan Dost
The Effect Of Vitamin D Status On Different Neuromuscular Blocker Agents Reverse Time, İlknur Sui̇di̇ye Yorulmaz, Yavuz Demi̇raran, Onur Özlü, Burhan Dost
Turkish Journal of Medical Sciences
Background/aim: This study is aimed to investigate the effects of vitamin D levels on sugammadex and neostigmine reversal times. Material and methods: Eighty patients between the ages of 18 and 65 years, with ASA I-III status who were undergoing surgery under general anesthesia were included in the study. A double blind fashion was used to randomly divide all the patients into two groups. At the end of the operation, sugammadex 2 mg/kg was administered to one group (Group sugammadex) and atropine and neostigmine was administered to the other group (Group neostigmine) intravenously. In the data analysis stage, the group was …
Mean Platelet Volume And Response To The First Line Therapy In Newly Diagnosed Adultimmune Thrombocytopenia Patients: A Retrospective Study, Erman Akkuş, Çi̇ğdem Fi̇dan, Gülşah Demi̇rci̇, Ali̇ Aytuğ Kuştaş, Meltem Yüksel
Mean Platelet Volume And Response To The First Line Therapy In Newly Diagnosed Adultimmune Thrombocytopenia Patients: A Retrospective Study, Erman Akkuş, Çi̇ğdem Fi̇dan, Gülşah Demi̇rci̇, Ali̇ Aytuğ Kuştaş, Meltem Yüksel
Turkish Journal of Medical Sciences
Background/aim: Immune thrombocytopenia (ITP) is treated by corticosteroids and/or intravenous immune globulin as the first line treatment when necessary. Mean platelet volume (MPV) is a marker of platelet production and function. In this study, we aimed to search the relationship between the MPV and the treatment response in ITP patients and it was hypothesized that MPV can be used as a predictor of the response. Materials and methods: The 70 newly diagnosed adult primary ITP patients and 70 of healthy people were included. MPV between ITP and healthy population, MPV in the diagnosis and after the treatment between the responders …
The Assessment Of Skin Sebum And Moisture Content Of Infants With Atopic Dermatitis, Hati̇ce Güneş, Hülya Nazi̇k, Mehmet Yaşar Özkars, Nurgül Parlak, Ayten Yildiz, Ömer Duyuran, Bahaüddi̇n Ahmed Yalçin
The Assessment Of Skin Sebum And Moisture Content Of Infants With Atopic Dermatitis, Hati̇ce Güneş, Hülya Nazi̇k, Mehmet Yaşar Özkars, Nurgül Parlak, Ayten Yildiz, Ömer Duyuran, Bahaüddi̇n Ahmed Yalçin
Turkish Journal of Medical Sciences
Background/aim: Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by dry skin, pruritus and eczematous lesions. The aim of this study is to evaluate the skin moisture and sebum content of the infants with AD and its relationship between the disease severity. Materials and methods: For this cross-sectional and case-control study we included 49 infants with AD aged between 2 and 24 months and 34 healthy infants with the same age and sex as a control group. Skin moisture and sebum content were measured by the bio- impedance method and recorded. Skin prick tests, total IgE levels and …
Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz
Thiol/Disulphide Homeostasis In Intensive Care Unit Patients With Sepsis And Septic Shock, Hami̇t Yildiz
Turkish Journal of Medical Sciences
Background/aim: Sepsis is a condition caused by infection followed by unregulated inflammatory response which may lead to organ dysfunction. The aim of this study is to be the first in the literature and it has been designed to show the thiol/disulphide changes in patients with sepsis and septic shock and their correlation with acute phase reactants. Material and methods: A total of 113 patients (septic shock 53 and sepsis 60) and 60 healthy control subjects have been enrolled in this study from the period February 2018 to 2019. The patients were divided in 2 groups: nonsurvivors (74) and survivors (39). …
Cross-Cultural Adaptation, Reliability And Validity Of The Turkish Version Of Patient-Specific Functional Scale In Patients With Chronic Neck Pain, Gamze Yalçinkaya, Bi̇lge Kara, Mehmet Nuri̇ Arda
Cross-Cultural Adaptation, Reliability And Validity Of The Turkish Version Of Patient-Specific Functional Scale In Patients With Chronic Neck Pain, Gamze Yalçinkaya, Bi̇lge Kara, Mehmet Nuri̇ Arda
Turkish Journal of Medical Sciences
Background/aim: Current clinical guidelines recommend to use both clinical and self-reported measurements for evaluation of chronic neck pain. Among the self-reported outcomes, Neck disability index and patient-specific functional scale are the most widely used and recommended instruments. The purpose of our study was to determine the test-retest reliability and validity of patient-specific functional scale which was not validated in Turkish language previously. Materials and methods: Translation and adaptation process had conducted according to the Beaton et al. Sociodemographic data, Turkish version of patient-specific functional scale and neck disability index were recorded at the initial assessment. Retest assessment was produced for …
The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler
The Association Between The Route Of Nutrition And Serum Levels Of Adipokines In Critical Illness: A Pilot Study, Kürşat Gündoğan, Ender Doğan, Nurhayat Tuğra Özer, Gülşah Güneş Şahi̇n, Serap Şahi̇n, Murat Sungur, İsmai̇l Hakki Akbudak, Sabahatti̇n Muhtaroğlu, Muhammet Güven, Thomas R. Ziegler
Turkish Journal of Medical Sciences
Background/aim: Adipokines play an important role in the regulation of metabolism. In critical illness, they alter serum levels and are suspected to worsen clinical outcomes. But the effect of the route of nutrition on adipokines is not known. The purpose of this study was to evaluate the association between the route of nutrition and adipokine levels in critically ill patients. Materials and methods: This prospective study was performed in an intensive care unit (ICU). Patients admitted to the ICU for least 72 h and receiving either enteral nutrition (EN) via tube feeding or parenteral nutrition (PN) were enrolled. Serum was …
Validating The Turkish Version Of The Weinstein Noise Sensitivity Scale: Effects Of Age, Sex, And Education Level, Meli̇s Keski̇n Yildiz, Yusuf Kemal Kemaloğlu, Yetki̇n Tuaç, Güven Mengü, Recep Karamert, Çağil Gökdoğan
Validating The Turkish Version Of The Weinstein Noise Sensitivity Scale: Effects Of Age, Sex, And Education Level, Meli̇s Keski̇n Yildiz, Yusuf Kemal Kemaloğlu, Yetki̇n Tuaç, Güven Mengü, Recep Karamert, Çağil Gökdoğan
Turkish Journal of Medical Sciences
Background/aim: Subjective noise sensitivity (SNS) is not only one of the most important predictors of perceived noise annoyance for the subjects exposed to the noise, but also strongly related with some psychological conditions and poor health perception of the subjects. Weinstein's Noise Sensitivity Scale (WNSS) is widely used for measuring of SNS. Materials and methods: In this study we adapted WNSS to Turkish (Tr-WNSS) and evaluated its psychometric properties and effect of age, sex and education level on SNS. Results: The study included 105 males and 105 female subjects between 18 and 55 years of age. Conclusion: Our data demonstrated …