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Articles 76501 - 76530 of 325181

Full-Text Articles in Medicine and Health Sciences

A Narrative Review Of Scars After Surgery: What To Expect, Kathryn Landers, Michelle Hwang, Elizabeth Cottrill Jun 2023

A Narrative Review Of Scars After Surgery: What To Expect, Kathryn Landers, Michelle Hwang, Elizabeth Cottrill

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

Background and Objective: For most surgical procedures, postoperative scars are inevitable. Scars that heal with poor cosmetic appearance or physical symptoms such as pain, pruritis, or tethering can have a negative impact on a patient’s quality of life. This review aims to identify current techniques for prevention of unfavorable scar formation and treatment of unfavorable scars.

Methods: A narrative review of the literature was conducted using our institution’s Primo search engine to search online databases including PubMed and EBSCO, among others. Included references were selected by the first author based on relevance to the subject matter and availability in English. …


Prevalence And Burden Of Gastrointestinal Parasites Among University Students At Dar Es Salaam University College Of Education, Tanzania, Magreth Fulgence, Ummul-Khair Mustafa, Jared S. Bakuza Jun 2023

Prevalence And Burden Of Gastrointestinal Parasites Among University Students At Dar Es Salaam University College Of Education, Tanzania, Magreth Fulgence, Ummul-Khair Mustafa, Jared S. Bakuza

Tanzania Journal of Science

Gastrointestinal parasites cause major health problems in many tropical and sub-tropical countries including Tanzania. However, information on the status of these infections is often scanty, especially among young adults including students in higher learning institutions.  During December 2020 to June 2021, a total of 272 faecal samples from university students at Dar es Salaam University College of Education (DUCE) were examined for parasites using the Kato Katz technique and analysed for infection levels based on standard guidelines. Detected parasites were identified as Schistosoma mansoni (8.1%), hookworms (1.5%), Trichuris trichiura (0.4%) and Hymenolepis diminuta (0.4%), with an overall prevalence of 10.4%. …


The Acceptance Of Covid-19 Vaccine: The Projection From The First Year Of Covid-19 Pandemic In Indonesia, Rimawati Aulia Insani Sadarang, Tri Addya Karini, Yessy Kurniati Jun 2023

The Acceptance Of Covid-19 Vaccine: The Projection From The First Year Of Covid-19 Pandemic In Indonesia, Rimawati Aulia Insani Sadarang, Tri Addya Karini, Yessy Kurniati

Preventia: The Indonesian Journal of Public Health

This study aimed to describe the acceptance of the COVID-19 vaccine and to discover predictive factors of vaccine acceptance in Indonesia. A cross-sectional study with 164 respondents found that 70.1% would accept the vaccine. Trust in government press releases, perception of infection risk, and age were significant factors. Logistic regression showed a predictive model with 73% performance, highlighting the importance of government trust and evidence-based messaging.


The Impact Of Health Promotion About E-Cigarettes Risk Among Adolescents, Dian Mawarni, Shofiyatul Masyiyah, Anis Yunita, Nazira Dyah Maharani Jun 2023

The Impact Of Health Promotion About E-Cigarettes Risk Among Adolescents, Dian Mawarni, Shofiyatul Masyiyah, Anis Yunita, Nazira Dyah Maharani

Preventia: The Indonesian Journal of Public Health

The increasing prevalence of cigarette users in the younger generation is clear evidence that cigarettes are increasingly popular, especially e-cigarettes. Misinformation and misperceptions circulating in the community as well as the role of the media add to concerns about the impact that e-cigarettes can have. Therefore, a transformation of health promotion efforts to save future generations from the dangers of e- cigarettes is needed. This study aimed to analyze the effect of health promotion media in reducing the willingness to smoke e- cigarettes in adolescents. This study used a quantitative analytic design with primary data. The instrument used was a …


Literature Study: Analysis Of The Relationship Between Age And The Incidence Of Postpartum Hemorrhage In Maternity Mothers, Tatut Isna Winanda Putri Pratiwi, Indah Ayu Afsari, Syifa'ul Lailiyah Jun 2023

Literature Study: Analysis Of The Relationship Between Age And The Incidence Of Postpartum Hemorrhage In Maternity Mothers, Tatut Isna Winanda Putri Pratiwi, Indah Ayu Afsari, Syifa'ul Lailiyah

Preventia: The Indonesian Journal of Public Health

Postpartum hemorrhage is the leading cause of maternal death worldwide with an incidence of 5 – 10 percent of all deliveries. Data shows a downward trend in maternal mortality in Indonesia in 1991 from 390 to 230 in 2020 per 100,000 live births. Maternal mortality is an important concern because being one of the indicators of health status and the success of health development, the reduction in maternal mortality rate is also a target in the Sustainable Development Goals (SDGs). In the SDGs, the target of reducing the maternal mortality rate is 70 per 100,000 live births by 2030. The …


Analysis Of Implementation Of Clean And Healthy Lifestyle Behavior (Phbs) During The Covid-19 Pandemic At Islamic Boarding School X, Malang City, Endang Sri Redjeki, Windi Chusniah Rachmawati, Tiara Dhea Yurisdian Jun 2023

Analysis Of Implementation Of Clean And Healthy Lifestyle Behavior (Phbs) During The Covid-19 Pandemic At Islamic Boarding School X, Malang City, Endang Sri Redjeki, Windi Chusniah Rachmawati, Tiara Dhea Yurisdian

Preventia: The Indonesian Journal of Public Health

Clean and Healthy Lifestyle Behavour (PHBS) is a set of behaviors that are practiced on the basis of awareness as learning outcomes that make a person, a family, a group, and community able to help themselves in the health sector and play an active role in realizing public health. It is still an effort to cultivate clean and healthy living behavior in Islamic boarding schools, as well as to recognize problems and levels of their health, and to be able to overcome, maintain, improve and protect their own health. This study aims to determine and analyze the implementation of PHBS …


Analysis Of Nitrogen, Phosporus And Potassium Concentration In Liquid Organic Fertlizers Of Vegetable Waste, Charcoal And Snails, Fika Fatwa Anin Nafis, Djoko Kustono, Anindya Hapsari Jun 2023

Analysis Of Nitrogen, Phosporus And Potassium Concentration In Liquid Organic Fertlizers Of Vegetable Waste, Charcoal And Snails, Fika Fatwa Anin Nafis, Djoko Kustono, Anindya Hapsari

Preventia: The Indonesian Journal of Public Health

Nitrogen, phosphorus and potassium concentration in liquid organic fertilizer can be obtained from organic materials. Liquid organic fertilizer can be made from vegetable waste, charcoal, and gold snail (Pomacea canaliculata L.). This study aimed to know the concentration of nitrogen, phosphorus and potassium in liquid organic fertilizers of waste vegetable, charcoal and snail. Methods used to test nitrogen was the Kjeldahl method, while potassium and phosphorus tested with spectrophotometer. The results showed that the concentration of nitrogen, phosphorus and potassium in liquid organic fertilizers of waste vegetable, charcoal and snail were 0,2612 percent; 0,0334 percent; and 0,1421 percent. This concentration …


Efektivitas Manual Therapy Dan Ultrasound Terhadap Peningkatan Fungsi Gerak Bahu Pada Kasus Nyeri Bahu Et Causa Bursitis Subacromialis Dengan Parameter Spadi Di Rsud Muhammad Natsir, Fadhilah Az-Zahra, Ronal Lufitos, Faizah Abdullah Djawas Jun 2023

Efektivitas Manual Therapy Dan Ultrasound Terhadap Peningkatan Fungsi Gerak Bahu Pada Kasus Nyeri Bahu Et Causa Bursitis Subacromialis Dengan Parameter Spadi Di Rsud Muhammad Natsir, Fadhilah Az-Zahra, Ronal Lufitos, Faizah Abdullah Djawas

Jurnal Fisioterapi Terapan Indonesia

ABSTRACT: Adhesive Capsulitis is a disorder that occurs in the shoulder area in the form of inflammation of the joint capsule which causes a feeling of stiffness and pain. Glenohumeral joint mobilization with the Maitland mobilization technique is using passive mobilization with physiological oscillatory movements which can produce a stretching effect and release of adhesive on the ligament capsule in the shoulder so that the range of motion of the shoulder joint can be increased. Hold relax is an exercise therapy with the principle of reciprocal inhibition which aims to improve antagonistic pattern relaxation, and mobilization, and to reduce pain. …


Neurodynamic Technique Terhadap Penurunan Nyeri, Peningkatan Grip Strength, Dan Peningkatan Kemampuan Fungsional Pada Carpal Tunnel Syndrome, Safrin Arifin, Fathia Dheanisa Jun 2023

Neurodynamic Technique Terhadap Penurunan Nyeri, Peningkatan Grip Strength, Dan Peningkatan Kemampuan Fungsional Pada Carpal Tunnel Syndrome, Safrin Arifin, Fathia Dheanisa

Jurnal Fisioterapi Terapan Indonesia

Carpal tunnel syndrome is a syndrome that occurs in 1-4% of the total population worldwide. This condition causes disruption of function and motion in the wrist that spreads to the fingers. Physiotherapy intervention is necessary to reduce the severity of symptoms in patients with CTS. Neurodynamic Techniques are nerve mobilization techniques that aim to restore homeostasis in the nerves so as to reduce pain and improve functional ability. Materials and methods. This research was conducted through searching several databases, found 31 articles which were then filtered and selected as many as 10 articles. However, of the 11 articles, further screening …


Aerobic Exercise Terhadap Peningkatan Endurance Pada Pasien Penyakit Jantung Koroner Dengan Pemeriksaan 6mwt : Studi Kasus, Dela Fariha Fuadi, Andrew Wijaya Saputra, Nabilla Nur Awaliah Dzatikhulwani Jun 2023

Aerobic Exercise Terhadap Peningkatan Endurance Pada Pasien Penyakit Jantung Koroner Dengan Pemeriksaan 6mwt : Studi Kasus, Dela Fariha Fuadi, Andrew Wijaya Saputra, Nabilla Nur Awaliah Dzatikhulwani

Jurnal Fisioterapi Terapan Indonesia

Background: Coronary heart disease (CHD) is a condition in which the heart's blood vessels (coronary arteries) are blocked by fat deposits. Based on data from Riskesdas (2018) it is revealed that cases of heart and blood vessel disease in Indonesia are increasing every year, increasing the mortality rate. This is due to the presence of risk factors that support the emergence of coronary heart disease. Objective: The aim of this paper is to evaluate the evaluation of aerobic exercise to increase endurance in patients with coronary heart disease by examining 6MWT. Method: This research is in the form of a …


Pengaruh Durasi Penggunaan Smartphone Di Kalangan Pelajar Terhadap Frekuensi Nyeri Leher, Irawan Wibisono, Didik Purnomo, Suci Amanati Jun 2023

Pengaruh Durasi Penggunaan Smartphone Di Kalangan Pelajar Terhadap Frekuensi Nyeri Leher, Irawan Wibisono, Didik Purnomo, Suci Amanati

Jurnal Fisioterapi Terapan Indonesia

Neck pain is a musculoskeletal problem that is often encountered in productive age, one of the triggers for neck pain is an unergonomic position for a long time. For example when using a smartphone, the position of the neck will tend towards the front. The use of smartphones in this technological era takes a long time. This is because smartphones have become part of student life. This study aims to determine the effect of the duration of smartphone use on the frequency of neck pain. This research method uses descriptive cross sectional with a total sample of 68 people, while …


Single Leg Depth Jump Kombinasi Core Plank Knee To Elbow Terhadap Power Otot Tungkai Atlet, Maya Triyanita, Siti Sardianti Dwi Tirta Jun 2023

Single Leg Depth Jump Kombinasi Core Plank Knee To Elbow Terhadap Power Otot Tungkai Atlet, Maya Triyanita, Siti Sardianti Dwi Tirta

Jurnal Fisioterapi Terapan Indonesia

Power limit training is defined as the movement to get a jump on athletes in doing the maximum jump smash. Badminton requires leg muscle explosive power because it is the muscle's ability to overcome loads and with a high speed of contraction. This study aims to determine the effect of the single leg depth jump exercise, the combination of the knee to elbow core plank, on increasing leg power in badminton athletes.

This study uses an experimental design method. This research was conducted on badminton athletes using a total sampling technique of 13 people, namely the Pliometric Simgle Leg Dept …


Penerapan Kerangka Acuan Biomekanik Pada Kasus Fraktur Distal Radius Ulna Dalam Kemandirian Membungkus Makanan, Hermito Gidion, Jasmine Putri Sugianto, Mahrus As’Ari, Purnama Betty Jun 2023

Penerapan Kerangka Acuan Biomekanik Pada Kasus Fraktur Distal Radius Ulna Dalam Kemandirian Membungkus Makanan, Hermito Gidion, Jasmine Putri Sugianto, Mahrus As’Ari, Purnama Betty

Jurnal Fisioterapi Terapan Indonesia

A distal radius fracture is a fracture that occurs when the radius bone, one of the two long bones in the forearm, breaks near the wrist. This paper aims to determine the application of the biomechanical frame of reference in cases of fractures of the distal radius ulna in the independence of wrapping food. This research was conducted by taking the case of a patient, conducting assessment, observation, and intervention on the patient. Specifically, the assessment carried out focuses on range of motion abilities, muscle strength and endurance, pain scale and functional activity abilities. The patient's problems were decreased joint …


What Were The Information Voids? A Qualitative Analysis Of Questions Asked By Dear Pandemic Readers Between August 2020-August 2021, Rachael Piltch-Loeb, Richard James, Sandra S. Albrecht, Alison M. Buttenheim, Jennifer Beam Dowd, Aparna Kumar, Malia Jones, Lindsey J. Leininger, Amanda Simanek, Shoshana Aronowitz Jun 2023

What Were The Information Voids? A Qualitative Analysis Of Questions Asked By Dear Pandemic Readers Between August 2020-August 2021, Rachael Piltch-Loeb, Richard James, Sandra S. Albrecht, Alison M. Buttenheim, Jennifer Beam Dowd, Aparna Kumar, Malia Jones, Lindsey J. Leininger, Amanda Simanek, Shoshana Aronowitz

College of Nursing Faculty Papers & Presentations

In the current infodemic, how individuals receive information (channel), who it is coming from (source), and how it is framed can have an important effect on COVID-19 related mitigation behaviors. In light of these challenges presented by the infodemic, Dear Pandemic (DP) was created to directly address persistent questions related to COVID-19 and other health topics in the online environment. This is a qualitative analysis of 3806 questions that were submitted by DP readers to a question box on the Dear Pandemic website between August 30, 2020 and August 29, 2021. Analyses resulted in four themes: the need for clarification …


Privacy Preserving Identification Of Population Stratification For Collaborative Genomic Research, Leonard Dervishi, Wenbiao Li, Anisa Halimi, Xiaoqian Jiang, Jaideep Vaidya, Erman Ayday Jun 2023

Privacy Preserving Identification Of Population Stratification For Collaborative Genomic Research, Leonard Dervishi, Wenbiao Li, Anisa Halimi, Xiaoqian Jiang, Jaideep Vaidya, Erman Ayday

Faculty, Staff and Student Publications

The rapid improvements in genomic sequencing technology have led to the proliferation of locally collected genomic datasets. Given the sensitivity of genomic data, it is crucial to conduct collaborative studies while preserving the privacy of the individuals. However, before starting any collaborative research effort, the quality of the data needs to be assessed. One of the essential steps of the quality control process is population stratification: identifying the presence of genetic difference in individuals due to subpopulations. One of the common methods used to group genomes of individuals based on ancestry is principal component analysis (PCA). In this article, we …


Development Of Photo-Polymerization-Type 3d Printer For High-Viscosity Ceramic Resin Using Cnn-Based Surface Defect Detection, Jin-Kyo Chung, Jeong-Seon Im, Min-Soo Park Jun 2023

Development Of Photo-Polymerization-Type 3d Printer For High-Viscosity Ceramic Resin Using Cnn-Based Surface Defect Detection, Jin-Kyo Chung, Jeong-Seon Im, Min-Soo Park

Faculty, Staff and Student Publications

Due to the high hardness and brittleness of ceramic materials, conventional cutting methods result in poor quality and machining difficulties. Additive manufacturing has also been tried in various ways, but it has many limitations. This study aims to propose a system to monitor surface defects that occur during the printing process based on high-viscosity composite resin that maximizes ceramic powder content in real time using image processing and convolutional neural network (CNN) algorithms. To do so, defects mainly observed on the surface were classified into four types by form: pore, minor, critical, and error, and the effect of each defect …


Three-Dimensional Comparison Between The Effects Of Mandibular Advancement Device And Maxillomandibular Advancement Surgery On Upper Airway, Marcela Gurgel, Lucia Cevidanes, Fabio Costa, Rowdley Pereira, Paulo Cunali, Lia Bittencourt, Antonio Ruellas, Joao Gonçalves, Jonas Bianchi, Cauby Chaves Jun 2023

Three-Dimensional Comparison Between The Effects Of Mandibular Advancement Device And Maxillomandibular Advancement Surgery On Upper Airway, Marcela Gurgel, Lucia Cevidanes, Fabio Costa, Rowdley Pereira, Paulo Cunali, Lia Bittencourt, Antonio Ruellas, Joao Gonçalves, Jonas Bianchi, Cauby Chaves

Pacific Faculty Work

Background: The efficacy of mandibular advancement devices (MAD) and maxillomandibular advancement (MMA) in improving upper airway (UA) patency has been described as being comparable to continuous positive airway pressure (CPAP) outcomes. However, no previous study has compared MAD and MMA treatment outcomes for the upper airway enlargement. This study aimed to evaluate three-dimensionally the UA changes and mandibular rotation in patients after MAD compared to MMA. Methods: The sample consisted of 17 patients with treated with MAD and 17 patients treated with MMA matched by weight, height, body mass index. Cone-beam computed tomography from before and after both treatments were …


Kinerja Rumah Sakit Dengan Pendekatan Balanced Scorecard (Bsc): Studi Kasus, Nabella Nabella, Wahyu Sulistiadi Jun 2023

Kinerja Rumah Sakit Dengan Pendekatan Balanced Scorecard (Bsc): Studi Kasus, Nabella Nabella, Wahyu Sulistiadi

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Regional General Hospitals as hospitals owned by local governments must provide the best service for the community, one way to assess the performance of the services provided is to use the Balanced Scorecard (BSC) method where this assessment does not only look at the financial perspective. but other aspects in the provision of health services to patients in hospitals. This study aims to see the results of the application of the use of the Balanced Scorecard (BSC) in the performance analysis of hospitals in Indonesia. This study uses a literature review method. Based on a study conducted by looking at …


Implementasi Lean Dalam Strategi Pemasaran Di Rumah Sakit Gigi Dan Mulut: Tinjauan Literatur, Arini Cyndwiana Prastiwi, Dumilah Ayuningtyas Jun 2023

Implementasi Lean Dalam Strategi Pemasaran Di Rumah Sakit Gigi Dan Mulut: Tinjauan Literatur, Arini Cyndwiana Prastiwi, Dumilah Ayuningtyas

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Hospitals as health services must make strategies in developing marketing activities so that they get a good response from the community. Oral and Dental Hospital (RSGM) is a health service that provides dental and oral health services in the form of prevention, treatment and recovery as well as providing emergency, outpatient, and inpatient services. The growing number of RSGM has forced health service management to plan the right marketing strategy to increase and maintain interest in patient visits. In addition, RSGM must also pay attention to service quality and cost efficiency. The benefits of lean in marketing can improve service …


Patient Safety Culture In Public General Hospitals: Literature Review, Rifa Fauziyyah, Masyitoh Basabih Jun 2023

Patient Safety Culture In Public General Hospitals: Literature Review, Rifa Fauziyyah, Masyitoh Basabih

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Background: The global prevalence of preventable adverse events in healthcare is a significant problem, with approximately 42.7 million annual accidents resulting in 23 million DALYs lost. Safety culture plays a crucial role in mitigating or exacerbating these incidents within hospitals. Objectives: To identify the results of the assessment of patient safety culture and the characteristics associated with patient safety culture in public general hospitals in various countries. Methods: This study was conducted between April-July 2021 utilizing a literature review approach using study searches through PubMed, Scopus, ScienceDirect, Google Scholar, and Garuda databases, and it discovered 17 papers from 2011-2021 that …


Pengembangan Sistem Pengajuan Cuti Online Pegawai Di Rumah Sakit Umum Anwar Medika, Eka Yusmanisari, Nur Andini Febrianti, Rhosita Dewi, Ulul Azmi Jun 2023

Pengembangan Sistem Pengajuan Cuti Online Pegawai Di Rumah Sakit Umum Anwar Medika, Eka Yusmanisari, Nur Andini Febrianti, Rhosita Dewi, Ulul Azmi

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The personnel department is the part in charge of handling the employee leave system. The employee leave system at Anwar Medika General Hospital is still done manually, using hardcopy documents or archives and not having a special database. This certainly affects the effectiveness and efficiency of work because officers have to input leave requests from many employees every day, which of course takes a long time to manage the data and adds to the workload of the staffing department. For that we need an information system that can handle these problems. The activities carried out aim to provide an overview …


Elevated Copeptin Levels Are Associated With Heart Failure Severity And Adverse Outcomes In Children With Cardiomyopathy, Karan B Karki, Jeffrey A Towbin, Samir H Shah, Ranjit R Philip, Alina N West, Sachin D Tadphale, Arun Saini Jun 2023

Elevated Copeptin Levels Are Associated With Heart Failure Severity And Adverse Outcomes In Children With Cardiomyopathy, Karan B Karki, Jeffrey A Towbin, Samir H Shah, Ranjit R Philip, Alina N West, Sachin D Tadphale, Arun Saini

Faculty, Staff and Students Publications

In children with cardiomyopathy, the severity of heart failure (HF) varies. However, copeptin, which is a biomarker of neurohormonal adaptation in heart failure, has not been studied in these patients. In this study, we evaluated the correlation of copeptin level with functional HF grading, B-type natriuretic peptide (BNP), and echocardiography variables in children with cardiomyopathy. Furthermore, we determined if copeptin levels are associated with adverse outcomes, including cardiac arrest, mechanical circulatory support, heart transplant, or death. In forty-two children with cardiomyopathy with a median (IQR) age of 13.1 years (2.5–17.2) and a median follow-up of 2.5 years (2.2–2.7), seven (16.7%) …


Twenty-Year Survival Following Lung Transplantation, John James Miggins, Ross M Reul, Spencer Barrett, Abbas Rana, Ahmed Alnajar, Jordan Dunson, Alexis Shafii, Puneet Garcha, John Goss, Gabriel Loor Jun 2023

Twenty-Year Survival Following Lung Transplantation, John James Miggins, Ross M Reul, Spencer Barrett, Abbas Rana, Ahmed Alnajar, Jordan Dunson, Alexis Shafii, Puneet Garcha, John Goss, Gabriel Loor

Faculty, Staff and Students Publications

BACKGROUND: Lung transplantation median survival has seen improvements due to recognition of short-term survival factors but continues to trail behind other solid organs due to limited understanding of long-term survivorship. Given the creation of the United Network for Organ Sharing (UNOS) database in 1986, it was difficult to accrue data on long-term survivors until recently. This study characterizes factors impacting lung transplant survival beyond 20 years, conditional to 1-year survival.

METHODS: Lung transplant recipients listed in UNOS from 1987 to 2002 who survived to 1 post-transplant year were reviewed. Kaplan-Meier and adjusted Cox regression analyses were performed at 20 and …


Co-Targeting Fasn And Mtor Suppresses Uveal Melanoma Growth, Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, William J. Harbour, Zachary T. Schug, Andrew E. Aplin Jun 2023

Co-Targeting Fasn And Mtor Suppresses Uveal Melanoma Growth, Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, William J. Harbour, Zachary T. Schug, Andrew E. Aplin

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Uveal melanoma (UM) displays a high frequency of metastasis; however, effective therapies for metastatic UM are limited. Identifying unique metabolic features of UM may provide a potential targeting strategy. A lipid metabolism protein expression signature was induced in a normal choroidal melanocyte (NCM) line transduced with GNAQ (Q209L), a driver in UM growth and development. Consistently, UM cells expressed elevated levels of fatty acid synthase (FASN) compared to NCMs. FASN upregulation was associated with increased mammalian target of rapamycin (mTOR) activation and sterol regulatory element-binding protein 1 (SREBP1) levels. FASN and mTOR inhibitors alone significantly reduced UM cell growth. Concurrent …


Analisis Manajemen Risiko Pasien Jatuh Di Instalasi Rawat Inap Rsia Xyz Jakarta Timur, Rani Umina, Vetty Yulianty Permanasari Jun 2023

Analisis Manajemen Risiko Pasien Jatuh Di Instalasi Rawat Inap Rsia Xyz Jakarta Timur, Rani Umina, Vetty Yulianty Permanasari

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

The incidence of patients fall is a second big issue after the incidence of medication errors. Reducing the risk of falls is one measure of service quality that is the main focus of the Hospital. This study aims to analyze the risk management of inpatient falls at Woman and Children Hospital SMB in 2020 by using FMEA tool. This research is a qualitative study by using in-depth interviews, observation, document review, and FGD as data collection methods. The results of this study indicate that factors of patient fall which become high priority potential failure modes are found in the structure …


Ndufs4 Regulates Cristae Remodeling In Diabetic Kidney Disease, Koki Mise, Jianyin Long, Daniel L Galvan, Zengchun Ye, Guizhen Fan, Irina I Serysheva, Travis I Moore, Jun Wada, Paul T Schumacker, Benny H Chang, Farhad R Danesh Jun 2023

Ndufs4 Regulates Cristae Remodeling In Diabetic Kidney Disease, Koki Mise, Jianyin Long, Daniel L Galvan, Zengchun Ye, Guizhen Fan, Irina I Serysheva, Travis I Moore, Jun Wada, Paul T Schumacker, Benny H Chang, Farhad R Danesh

Faculty, Staff and Student Publications

The mitochondrial electron transport chain (ETC) is a highly adaptive process to meet metabolic demands of the cell, and its dysregulation has been associated with diverse clinical pathologies. However, the role and nature of impaired ETC in kidney diseases remains poorly understood. Here, we generated diabetic mice with podocyte-specific overexpression of Ndufs4, an accessory subunit of mitochondrial complex I, as a model to investigate the role of ETC integrity in diabetic kidney disease (DKD). We find that these conditional mice exhibit significant improvements in cristae morphology, mitochondrial dynamics, and albuminuria. By coupling proximity labeling with super-resolution imaging, we also identify …


Challenges In Diagnosing Staphylococcal Scalded Skin Syndrome In Children With Kwashiorkor: A Case Report, Christie Hamdali, Sondang Sirait, Adria Rusvita, Bawono Bhakti Jun 2023

Challenges In Diagnosing Staphylococcal Scalded Skin Syndrome In Children With Kwashiorkor: A Case Report, Christie Hamdali, Sondang Sirait, Adria Rusvita, Bawono Bhakti

Journal of General - Procedural Dermatology and Venereology Indonesia

Staphylococcal scalded skin syndrome (SSSS) is a type of exfoliating skin disease with high incidence in children. This condition can cause serious morbidity and even mortality with certain comorbid diseases such as malnutrition. Malnutrition could mask the diagnosis of SSSS because of its similarity to numerous differential diagnoses. Accuracy of clinical diagnosis is then essential to determine the proper initial management. This case report presents a 6-month-old male baby with staphylococcal scalded skin syndrome and kwashiorkor. The patient presented with complaints of multiple erythematous plaques and widespread vesicular lesions that subsequently ruptured, resulting in erosions. Physical examination revealed edema, coarse …


The Effect Of Topical Oatmeal (Avena Sativa) On Hydration-Related Skin Disorders: A Systematic Review, Karenina Novani Sugondo, Melyawati Hermawan Jun 2023

The Effect Of Topical Oatmeal (Avena Sativa) On Hydration-Related Skin Disorders: A Systematic Review, Karenina Novani Sugondo, Melyawati Hermawan

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: In recent years, interest in developing cosmetics and beauty products based on natural ingredients has increased. The addition of herbal extracts to products could improve the effectiveness of therapy. One of the natural ingredients that can be found is oatmeal. Oatmeal has been used for a long time and has been approved by the U.S. Food and Drug Administration as a skin protective agent since 2003. This study aims to systematically review the literature to determine the effect of topical oatmeal (Avena sativa) on hydration-related skin disorders.

Methods: A total of 9,538 studies were found in the database sources …


Zosteriform Cutaneous Metastases From A Carcinoma Mammae, Kharisma Yuliasis Widiasri, Ayu Wikan Sayekti, Novian Febiyanto, Elliana Wahyuanggradewi, Jeffrey Giantoro, Satiti Retno Pudjiati, Hanggoro Tri Rinonce, Agnes Sri Siswati Jun 2023

Zosteriform Cutaneous Metastases From A Carcinoma Mammae, Kharisma Yuliasis Widiasri, Ayu Wikan Sayekti, Novian Febiyanto, Elliana Wahyuanggradewi, Jeffrey Giantoro, Satiti Retno Pudjiati, Hanggoro Tri Rinonce, Agnes Sri Siswati

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Cutaneous metastases were reported in 18.6-26.5% of breast cancer patients. Zosteriform cutaneous metastasis is an unusual and rare morphological variant. Clinicians, especially dermatovenereologists, should consider dermatomal cutaneous metastases in oncology patients aside from herpes zoster, which is common in this population.

Case Illustration: A 62-year-old woman presented with clustered papules and vesicles with an erythematous base, sometimes painful, on the right side of the chest in T5-T7 dermatomal distribution of 1-month duration. She had undergone a radical mastectomy for breast carcinoma and had been receiving chemoradiotherapy, which was completed in March 2018. A diagnosis of zosteriform cutaneous …


Therapy Selection For Tinea Corporis And Cruris With Commorbidity: 3 Case Series, Yefta Yefta, Dwi Retno Adi Winarni, Agnes Sri Siswati Jun 2023

Therapy Selection For Tinea Corporis And Cruris With Commorbidity: 3 Case Series, Yefta Yefta, Dwi Retno Adi Winarni, Agnes Sri Siswati

Journal of General - Procedural Dermatology and Venereology Indonesia

Background: Dermatophytosis is a superficial (skin, hair and nails) fungal infection caused by dermatophyte group fungi (Trichophyton, Epidermophyton and Microsporum). Immunocompromised conditions cause fungal infections to become more widespread and require consideration of therapy.

Case Illustration: This case series represented three cases of tinea corporis and tinea cruris in patients with comorbidities. The first case was tinea corporis and tinea cruris in a patient with congestive heart failure with oral terbinafine therapy. The second case was tinea corporis and tinea cruris in a patient with bilateral fourth degree hydronephrosis with oral griseofulvin therapy. The third case was tinea …