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Articles 76201 - 76230 of 325259

Full-Text Articles in Medicine and Health Sciences

Umbilical Cord Hemangioma And Pseudocyst With Favorable Fetal Outcome, Sikolia Wanyonyi, Felix Nyagaka, Patricia Okiro, Lilian Ogutu, Alice Nyaichowa, Felix Oindi, Evan Sequeira Jul 2023

Umbilical Cord Hemangioma And Pseudocyst With Favorable Fetal Outcome, Sikolia Wanyonyi, Felix Nyagaka, Patricia Okiro, Lilian Ogutu, Alice Nyaichowa, Felix Oindi, Evan Sequeira

Obstetrics and Gynaecology, East Africa

Umbilical cord hemangiomas are rare neoplasms of vascular origin, commonly found in the free section of the umbilical cord proximal to placental insertion. They are associated with an increased risk of fetal mortality. We present a rare co- occurrence of an umbilical cord hemangioma and a pseudocyst managed conservatively, with favorable fetal outcome despite the interval increase in size, decreased caliber of the umbilical arteries, and fetal chest compression.


Effects Of Covid-19 On The Autonomic Cardiovascular System: Heart Rate Variability And Turbulence In Recovered Patients, Sedat Taş, Ümmü Taş Jul 2023

Effects Of Covid-19 On The Autonomic Cardiovascular System: Heart Rate Variability And Turbulence In Recovered Patients, Sedat Taş, Ümmü Taş

The Texas Heart Institute Journal

BACKGROUND: COVID-19 may be a risk factor for developing cardiovascular autonomic dysfunction. Data are limited, however, on the association between heart rate variability, heart rate turbulence, and COVID-19. The aims of this study were to evaluate the effect of COVID-19 on the cardiovascular autonomic system in patients with persistent symptoms after recovering from COVID-19 and to determine whether these patients showed changes in ambulatory electrocardiography monitoring.

METHODS: Fifty-one adults who had confirmed SARS-CoV-2 infection and presented with persistent symptoms to the cardiology outpatient clinic after clinical recovery between April and June 2021 were included. Patients were prospectively followed for 6 …


Sex-Based Differences In The Presentation And Outcomes Of Acute Pulmonary Embolism: A Systematic Review And Meta-Analysis, Yu Zhang, Yu Qiu, Jinming Luo, Jian Zhang, Qingqing Yan Jul 2023

Sex-Based Differences In The Presentation And Outcomes Of Acute Pulmonary Embolism: A Systematic Review And Meta-Analysis, Yu Zhang, Yu Qiu, Jinming Luo, Jian Zhang, Qingqing Yan

The Texas Heart Institute Journal

BACKGROUND: The study aimed to review differences in the presentation and outcomes of acute pulmonary embolism (PE) between men and women.

METHODS: PubMed, CENTRAL, Web of Science, and Embase were searched for studies comparing clinical features or outcomes of PE between men and women. Baseline comorbidities, risk factors, clinical features, and mortality rates were also compared between men and women.

RESULTS: Fourteen studies were included. It was noted that men presented with PE at a statistically significantly younger age than women (P < .001). Smoking history (P < .001), lung disease (P = .004), malignancy (P = .02), and unprovoked PE (P = .004) were significantly more frequent among men than among women. There was no difference between the sexes for hypertension, diabetes, and a history of recent immobilization. A significantly higher proportion of men presented with chest pain (P = .02) and hemoptysis (P < .001), whereas syncope (P = .005) was more frequent in women. Compared with men, women had a higher proportion of high-risk PE (P = .003). There was no difference in the use of thrombolytic therapy or inferior vena cava filter. Neither crude nor adjusted mortality rates were significantly different between men and women.

CONCLUSION: This review found that the age at presentation, comorbidities, and symptoms of PE differed between men and …


Diabetes Technology Meeting 2022, Jingtong Huang, Andrea M Yeung, Ashley Y Dubord, Howard Wolpert, Peter G Jacobs, Wei-An Lee, Andjela Drincic, Elias K Spanakis, Jennifer L Sherr, Priya Prahalad, Alexander Fleming, Victoria C Hsiao, Tejaswi Kompala, Rayhan A Lal, Maya Fayfman, Barry H Ginsberg, Rodolfo J Galindo, Andreas Stuhr, J Geoffrey Chase, Bijan Najafi, Umesh Masharani, Jane Jeffrie Seley, David C Klonoff Jul 2023

Diabetes Technology Meeting 2022, Jingtong Huang, Andrea M Yeung, Ashley Y Dubord, Howard Wolpert, Peter G Jacobs, Wei-An Lee, Andjela Drincic, Elias K Spanakis, Jennifer L Sherr, Priya Prahalad, Alexander Fleming, Victoria C Hsiao, Tejaswi Kompala, Rayhan A Lal, Maya Fayfman, Barry H Ginsberg, Rodolfo J Galindo, Andreas Stuhr, J Geoffrey Chase, Bijan Najafi, Umesh Masharani, Jane Jeffrie Seley, David C Klonoff

Center on Aging Staff Publications

Diabetes Technology Society hosted its annual Diabetes Technology Meeting from November 3 to November 5, 2022. Meeting topics included (1) the measurement of glucose, insulin, and ketones; (2) virtual diabetes care; (3) metrics for managing diabetes and predicting outcomes; (4) integration of continuous glucose monitor data into the electronic health record; (5) regulation of diabetes technology; (6) digital health to nudge behavior; (7) estimating carbohydrates; (8) fully automated insulin delivery systems; (9) hypoglycemia; (10) novel insulins; (11) insulin delivery; (12) on-body sensors; (13) continuous glucose monitoring; (14) diabetic foot ulcers; (15) the environmental impact of diabetes technology; and (16) spinal …


Epidemiology Of Nonsyndromic, Orofacial C/Lefts In Texas: Differences By Cleft Type And Presence Of Additional Defects, Maria Luisa Navarro Sanchez, Michael D Swartz, Peter H Langlois, Mark A Canfield, A J Agopian Jul 2023

Epidemiology Of Nonsyndromic, Orofacial C/Lefts In Texas: Differences By Cleft Type And Presence Of Additional Defects, Maria Luisa Navarro Sanchez, Michael D Swartz, Peter H Langlois, Mark A Canfield, A J Agopian

Faculty, Staff and Student Publications

To describe the current epidemiology of nonsyndromic cleft palate alone (CP) and cleft lip with or without cleft palate (CL ± P) in Texas and examine differences in the characteristics of infants with CP and CL ± P based on the presence/absence of additional defects. We used data from the Texas Birth Defects Registry, a statewide active birth defect surveillance system, from 1815 cases with CP and 5066 with CL ± P, without a syndrome diagnosis (1999-2014 deliveries). All live births in Texas were used for comparison. Poisson regression was used to calculate crude and adjusted prevalence ratios (aPR) for …


Arsenic Metabolism, Diabetes Prevalence, And Insulin Resistance Among Mexican Americans: A Mendelian Randomization Approach, Margaret C Weiss, Yu-Hsuan Shih, Molly Scannell Bryan, Brian P Jackson, David Aguilar, Eric L Brown, Goo Jun, Craig L Hanis, Maria Argos, Robert M Sargis Jul 2023

Arsenic Metabolism, Diabetes Prevalence, And Insulin Resistance Among Mexican Americans: A Mendelian Randomization Approach, Margaret C Weiss, Yu-Hsuan Shih, Molly Scannell Bryan, Brian P Jackson, David Aguilar, Eric L Brown, Goo Jun, Craig L Hanis, Maria Argos, Robert M Sargis

Faculty, Staff and Student Publications

BACKGROUND: Differences in arsenic metabolism capacity may influence risk for type 2 diabetes, but the mechanistic drivers are unclear. We evaluated the associations between arsenic metabolism with overall diabetes prevalence and with static and dynamic measures of insulin resistance among Mexican Americans living in Starr County, Texas.

METHODS: We utilized data from cross-sectional studies conducted in Starr County, Texas, from 2010-2014. A Mendelian randomization approach was utilized to evaluate the associations between arsenic metabolism and type 2 diabetes prevalence using the intronic variant in the arsenic methylating gene, rs9527, as the instrumental variable for arsenic metabolism. to further assess mechanisms …


July 2023, Swosu Bulldog Wellness Committee Jul 2023

July 2023, Swosu Bulldog Wellness Committee

SWOSU BULLDOG WELLNESS

  • Healthy 4th of July Dinner Recipes!
  • July is National Blueberry Month!
  • July is National Ice Cream Month!
  • How to Stay Active in Warm Weather
  • Fireworks


Antithrombin, Protein C, And Protein S: Genome And Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels, Yuekai Ji, Gerard Temprano-Sagrera, Lori A Holle, Allison Bebo, Jennifer A Brody, Ngoc-Quynh Le, Kadri Kangro, Michael R Brown, Angel Martinez-Perez, Colleen M Sitlani, Pierre Suchon, Marcus E Kleber, David B Emmert, Ayse Bilge Ozel, Dre'von A Dobson, Weihong Tang, Dolors Llobet, Russell P Tracy, Jean-François Deleuze, Graciela E Delgado, Martin Gögele, Kerri L Wiggins, Juan Carlos Souto, James S Pankow, Kent D Taylor, David-Alexandre Trégouët, Angela P Moissl, Christian Fuchsberger, Frits R Rosendaal, Alanna C Morrison, Jose Manuel Soria, Mary Cushman, Pierre-Emmanuel Morange, Winfried März, Andrew A Hicks, Karl C Desch, Andrew D Johnson, Paul S De Vries, Charge Consortium Hemostasis Working Group, Invent Consortium, Alisa S Wolberg, Nicholas L Smith, Maria Sabater-Lleal Jul 2023

Antithrombin, Protein C, And Protein S: Genome And Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels, Yuekai Ji, Gerard Temprano-Sagrera, Lori A Holle, Allison Bebo, Jennifer A Brody, Ngoc-Quynh Le, Kadri Kangro, Michael R Brown, Angel Martinez-Perez, Colleen M Sitlani, Pierre Suchon, Marcus E Kleber, David B Emmert, Ayse Bilge Ozel, Dre'von A Dobson, Weihong Tang, Dolors Llobet, Russell P Tracy, Jean-François Deleuze, Graciela E Delgado, Martin Gögele, Kerri L Wiggins, Juan Carlos Souto, James S Pankow, Kent D Taylor, David-Alexandre Trégouët, Angela P Moissl, Christian Fuchsberger, Frits R Rosendaal, Alanna C Morrison, Jose Manuel Soria, Mary Cushman, Pierre-Emmanuel Morange, Winfried März, Andrew A Hicks, Karl C Desch, Andrew D Johnson, Paul S De Vries, Charge Consortium Hemostasis Working Group, Invent Consortium, Alisa S Wolberg, Nicholas L Smith, Maria Sabater-Lleal

Faculty, Staff and Student Publications

BACKGROUND: Antithrombin, PC (protein C), and PS (protein S) are circulating natural anticoagulant proteins that regulate hemostasis and of which partial deficiencies are causes of venous thromboembolism. Previous genetic association studies involving antithrombin, PC, and PS were limited by modest sample sizes or by being restricted to candidate genes. In the setting of the Cohorts for Heart and Aging Research in Genomic Epidemiology consortium, we meta-analyzed across ancestries the results from 10 genome-wide association studies of plasma levels of antithrombin, PC, PS free, and PS total.

METHODS: Study participants were of European and African ancestries, and genotype data were imputed …


A Mendelian Randomization Study Of Genetic Liability To Post-Traumatic Stress Disorder And Risk Of Ischemic Stroke, Opeyemi Soremekun, Clarisse Musanabaganwa, Annette Uwineza, Maddalena Ardissino, Skanda Rajasundaram, Agaz H Wani, Stefan Jansen, Jean Mutabaruka, Eugene Rutembesa, Chisom Soremekun, Cisse Cheickna, Mamadou Wele, Joseph Mugisha, Oyekanmi Nash, Eugene Kinyanda, Dorothea Nitsch, Myriam Fornage, Tinashe Chikowore, Dipender Gill, Derek E Wildman, Leon Mutesa, Monica Uddin, Segun Fatumo Jul 2023

A Mendelian Randomization Study Of Genetic Liability To Post-Traumatic Stress Disorder And Risk Of Ischemic Stroke, Opeyemi Soremekun, Clarisse Musanabaganwa, Annette Uwineza, Maddalena Ardissino, Skanda Rajasundaram, Agaz H Wani, Stefan Jansen, Jean Mutabaruka, Eugene Rutembesa, Chisom Soremekun, Cisse Cheickna, Mamadou Wele, Joseph Mugisha, Oyekanmi Nash, Eugene Kinyanda, Dorothea Nitsch, Myriam Fornage, Tinashe Chikowore, Dipender Gill, Derek E Wildman, Leon Mutesa, Monica Uddin, Segun Fatumo

Faculty, Staff and Student Publications

Observational studies have shown an association between post-traumatic stress disorder (PTSD) and ischemic stroke (IS) but given the susceptibility to confounding it is unclear if these associations represent causal effects. Mendelian randomization (MR) facilitates causal inference that is robust to the influence of confounding. Using two sample MR, we investigated the causal effect of genetic liability to PTSD on IS risk. Ancestry-specific genetic instruments of PTSD and four quantitative sub-phenotypes of PTSD, including hyperarousal, avoidance, re-experiencing, and total symptom severity score (PCL-Total) were obtained from the Million Veteran Programme (MVP) using a threshold P value (P) of <5 >× 10


Clonal Hematopoiesis Is Associated With Protection From Alzheimer's Disease, Hind Bouzid, Julia A Belk, Max Jan, Yanyan Qi, Chloé Sarnowski, Sara Wirth, Lisa Ma, Matthew R Chrostek, Herra Ahmad, Daniel Nachun, Winnie Yao, Alexa Beiser, Alexander G Bick, Joshua C Bis, Myriam Fornage, William T Longstreth, Oscar L Lopez, Pradeep Natarajan, Bruce M Psaty, Claudia L Satizabal, Joshua Weinstock, Eric B Larson, Paul K Crane, C Dirk Keene, Sudha Seshadri, Ansuman T Satpathy, Thomas J Montine, Siddhartha Jaiswal Jul 2023

Clonal Hematopoiesis Is Associated With Protection From Alzheimer's Disease, Hind Bouzid, Julia A Belk, Max Jan, Yanyan Qi, Chloé Sarnowski, Sara Wirth, Lisa Ma, Matthew R Chrostek, Herra Ahmad, Daniel Nachun, Winnie Yao, Alexa Beiser, Alexander G Bick, Joshua C Bis, Myriam Fornage, William T Longstreth, Oscar L Lopez, Pradeep Natarajan, Bruce M Psaty, Claudia L Satizabal, Joshua Weinstock, Eric B Larson, Paul K Crane, C Dirk Keene, Sudha Seshadri, Ansuman T Satpathy, Thomas J Montine, Siddhartha Jaiswal

Faculty, Staff and Student Publications

Clonal hematopoiesis of indeterminate potential (CHIP) is a premalignant expansion of mutated hematopoietic stem cells. As CHIP-associated mutations are known to alter the development and function of myeloid cells, we hypothesized that CHIP may also be associated with the risk of Alzheimer's disease (AD), a disease in which brain-resident myeloid cells are thought to have a major role. To perform association tests between CHIP and AD dementia, we analyzed blood DNA sequencing data from 1,362 individuals with AD and 4,368 individuals without AD. Individuals with CHIP had a lower risk of AD dementia (meta-analysis odds ratio (OR) = 0.64, P …


Proteomic Analysis Identifies Circulating Proteins Associated With Plasma Amyloid-Β And Incident Dementia, Adrienne Tin, Kevin J Sullivan, Keenan A Walker, Jan Bressler, Rajesh Talluri, Bing Yu, Jeanette Simino, Valborg Gudmundsdottir, Valur Emilsson, Lori L Jennings, Lenore Launer, Hao Mei, Eric Boerwinkle, B Gwen Windham, Rebecca Gottesman, Vilmundur Gudnason, Josef Coresh, Myriam Fornage, Thomas H Mosley Jul 2023

Proteomic Analysis Identifies Circulating Proteins Associated With Plasma Amyloid-Β And Incident Dementia, Adrienne Tin, Kevin J Sullivan, Keenan A Walker, Jan Bressler, Rajesh Talluri, Bing Yu, Jeanette Simino, Valborg Gudmundsdottir, Valur Emilsson, Lori L Jennings, Lenore Launer, Hao Mei, Eric Boerwinkle, B Gwen Windham, Rebecca Gottesman, Vilmundur Gudnason, Josef Coresh, Myriam Fornage, Thomas H Mosley

Faculty, Staff and Student Publications

BACKGROUND: Plasma amyloid-β (Aβ) (Aβ

METHODS: We analyzed the association of these 3 plasma Aβ measures with 4638 circulating proteins among a subset of the participants of the Atherosclerosis Risk in Communities (ARIC) study (midlife:

RESULTS: At midlife, of the 296 Aβ-associated proteins, 8 were associated with incident dementia from midlife and late life in the ARIC study, and NPPB, IBSP, and THBS2 were replicated in the AGES-Reykjavik Study. At late life, of the 34 Aβ-associated proteins, none were associated with incident dementia at midlife, and kidney function explained 10%, 12%, and 0.2% of the variance of Aβ

CONCLUSIONS: This …


How Multiple Myeloma Affect Those Who Care: Hidden Struggles, Pratibha Thakur, Jyothi Chakrabarty, Sharada Mailankody Jul 2023

How Multiple Myeloma Affect Those Who Care: Hidden Struggles, Pratibha Thakur, Jyothi Chakrabarty, Sharada Mailankody

Manipal Journal of Nursing and Health Sciences

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Prevalence Of Leprosy In Lower -Middle- Income And Upper -Middle-Income Countries: A Secondary Data Analysis, Venkatesh Ramaswamy Naik, Rishikha Jeyapal Jul 2023

Prevalence Of Leprosy In Lower -Middle- Income And Upper -Middle-Income Countries: A Secondary Data Analysis, Venkatesh Ramaswamy Naik, Rishikha Jeyapal

Manipal Journal of Nursing and Health Sciences

Abstract

To Study the Prevalence of Leprosy in Lower -Middle- Income and Upper -Middle-Income Countries

Introduction: Leprosy is an infectious disease affecting the nerves causing loss of sensation of touch and pain in the affected areas. The prevalence of leprosy in different countries has changed over time with the governments of the respective countries intensifying their efforts and working on various public health programs. Objective: This study aimed to look into the prevalence rates of leprosy per 1000000 population in lower-middle-income and upper-middle-income countries. Material and Method: The prevalence rates per 1000000 population were obtained from the Global Health Observatory …


Effectiveness Of Kaleidoscope On Pain And Behavioural Responses Among Children During Intravenous Cannulation- An Open-Label Randomised Controlled Study., Anju K S, Swapna K. Gopalan, Namitha P Jul 2023

Effectiveness Of Kaleidoscope On Pain And Behavioural Responses Among Children During Intravenous Cannulation- An Open-Label Randomised Controlled Study., Anju K S, Swapna K. Gopalan, Namitha P

Manipal Journal of Nursing and Health Sciences

Abstract

Introduction

Children experience significant pain and distress during paediatric procedures, especially during intravenous (IV) cannulation. Several non-pharmacological interventions are in use for this purpose. Many distraction techniques are suggested.

Methods

A randomised controlled trial was conducted among 60 children in the age group of 4-12 years undergoing first IV cannulation after admission to evaluate the effectiveness of kaleidoscope compared to standard treatment on pain and behaviour response. Through block randomisation, 30 children were allocated to each group. Standard tools were used to assess pain and behaviour response.

Results

Total 102 children were admitted to the paediatric ward during the …


Evaluation Of Nursing Diagnoses Perception Among Nursing Students, Pramilaa R Jul 2023

Evaluation Of Nursing Diagnoses Perception Among Nursing Students, Pramilaa R

Manipal Journal of Nursing and Health Sciences

Introduction: The basic quality of nursing practice is being compassionate and this quality is the one of the significant functions of the nursing profession .Nursing process manages the sick population holistically encompassing all domains such as socio cultural, psychological, economic and spiritual. It augments critical thinking too. Nursing process is also viewed in a resolution perspective. The objectives of the present study were carried to determine nursing students’ perceptions of nursing diagnoses and associate the level of perception with selected demographic variables. Methodology: A descriptive study to evaluate the nursing students’ perception of nursing diagnoses was conducted. Permission of the …


Determinants Of Nurse Turnover In Rural Primary Health Centres And Policies Adopted In India- A Systematic Integrative Review Protocol, Ponnambily Chandy Ms, Bart Criel Dr, Lakshmi L Dr Jul 2023

Determinants Of Nurse Turnover In Rural Primary Health Centres And Policies Adopted In India- A Systematic Integrative Review Protocol, Ponnambily Chandy Ms, Bart Criel Dr, Lakshmi L Dr

Manipal Journal of Nursing and Health Sciences

Background: Nurses act as the major workforce of the primary health care delivery system by representing nearly half of all health professionals in India. Nurse turnover in rural Primary Health Centers (PHCs) is receiving a great deal of attention around the world in both professional publications and media. We have conducted a rapid literature review and from thereon developed an analytical framework on the determinants of nurse turnover in rural PHCs and policies adopted in India to overcome it. Literature reviews on studies addressing the turnover of registered nurses working in the rural PHCs are scarce. The current review aims …


Effect Of Digital Health Interventions On Suicidal Prevention Among Adolescents - A Systematic Review Protocol, Ngangom Karorpati Chanu, Siva N, Ushapriya M, Shelmi Antony, Sarah Hulugoji, Baby S Nayak Jul 2023

Effect Of Digital Health Interventions On Suicidal Prevention Among Adolescents - A Systematic Review Protocol, Ngangom Karorpati Chanu, Siva N, Ushapriya M, Shelmi Antony, Sarah Hulugoji, Baby S Nayak

Manipal Journal of Nursing and Health Sciences

Introduction: Suicide is a global health crisis, ranking as the fourth leading cause of death among adolescents. The adolescent phase is marked by numerous challenges, such as increased academic pressures, evolving relationships with parents and peers, and self-identity development. Many of these suicides are preventable, but a significant number of young adolescents succumb to suicide due to a lack of awareness and access to support. Digital media, like all other forms of media, can either strengthen or weaken suicide prevention initiatives. Methods: A systematic review will adhere to the PRISMA guidelines. The systematic review will include randomized control trials of …


Pain, Hope And Caring, Michelle C. Dziurgot Dds Jul 2023

Pain, Hope And Caring, Michelle C. Dziurgot Dds

The Journal of the Michigan Dental Association

MDA Editor Michelle C. Dziurgot shares her breast cancer journey as a solo practitioner during the COVID-19 closure. Support from family, friends, and the dental community was crucial. The experience emphasizes the importance of offering a safety net and emotional support to colleagues facing personal challenges.


A Public Health Educational Campaign For Sudden Unexpected Infant Death (Suid) Intervention, Elia G. Peralta Landeros Jul 2023

A Public Health Educational Campaign For Sudden Unexpected Infant Death (Suid) Intervention, Elia G. Peralta Landeros

Master's Projects and Capstones

Purpose: The rate of infant mortality serves as a crucial indicator of the overall health of society (CDC, 2022). The five leading causes of infant mortality are birth defects, preterm birth, sudden infant death syndrome, injuries, and maternal pregnancy complications. The prevalence of infant mortality varies across states, with eastern states and minority-ethnicity infants having higher prevalence. This thesis proposes utilizing the Safe to Sleep framework to introduce Giving Breath, a public health education campaign that introduced breastfeeding as an intervention to Sudden Unexpected Infant Death (SUID).

Methods:

  1. Analyze current and new policies' impact on women's rights to breastfeed …


A Direct Fiber Approach To Model Sclera Collagen Architecture And Biomechanics, Fengting Ji, Manik Bansal, Bingrui Wang, Yi Hua, Mohammad R. Islam, Felix Matuschke, Markus Axer, Ian A. Sigal Jul 2023

A Direct Fiber Approach To Model Sclera Collagen Architecture And Biomechanics, Fengting Ji, Manik Bansal, Bingrui Wang, Yi Hua, Mohammad R. Islam, Felix Matuschke, Markus Axer, Ian A. Sigal

Mechanical Engineering Faculty Publications

Sclera collagen fiber microstructure and mechanical behavior are central to eye physiology and pathology. They are also complex, and are therefore often studied using modeling. Most models of sclera, however, have been built within a conventional continuum framework. In this framework, collagen fibers are incorporated as statistical distributions of fiber characteristics such as the orientation of a family of fibers. The conventional continuum approach, while proven successful for describing the macroscale behavior of the sclera, does not account for the sclera fibers are long, interwoven and interact with one another. Hence, by not considering these potentially crucial characteristics, …


Comparison Between The Effects Of Acute Physical And Psychosocial Stress On Feedback-Based Learning, Xiao Yang, Brittany Nackley, Bruce H. Friedman Jul 2023

Comparison Between The Effects Of Acute Physical And Psychosocial Stress On Feedback-Based Learning, Xiao Yang, Brittany Nackley, Bruce H. Friedman

Psychology Faculty Publications

Stress modulates feedback-based learning, a process that has been implicated in declining mental function in aging and mental disorders. While acute physical and psychosocial stressors have been used interchangeably in studies on feedback-based learning, the two types of stressors involve distinct physiological and psychological processes. Whether the two types of stressors differentially influence feedback processing remains unclear. The present study compared the effects of physical and psychosocial stressors on feedback-based learning. Ninety-six subjects (Mage = 19.11 years; 50 female) completed either a cold pressor task (CPT) or mental arithmetic task (MAT), as the physical or psychosocial stressor, while electrocardiography and …


The Role Of Psychological Safety On Employee Satisfaction And Retention In Healthcare Delivery Settings: A Systematic Literature Review, Jamey Paul Jul 2023

The Role Of Psychological Safety On Employee Satisfaction And Retention In Healthcare Delivery Settings: A Systematic Literature Review, Jamey Paul

Capstone Experience: Master of Public Health

The healthcare industry typically has a high rate of employee turnover due to higher job stresses and burnout, lower job satisfaction, and insufficient organizational support and work culture. This turnover has worsened since the onset of the COVID-19 pandemic. Psychological safety, a shared belief by organizational members that the team/unit is safe for interpersonal risk-taking, can be one of the many ingredients that contribute to employee satisfaction and reduce turnover. This systematic literature review explored the role of psychological safety on job satisfaction and retention of healthcare workers in delivery settings by synthesizing the known antecedents and outcomes of psychological …


The Time-Course Of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions In Female Skeletal Muscle Distinct From Males, Francielly Morena, Seongkyun Lim, Ana Regina Cabrera, Eleanor R. Schrems, Ronald G. Jones, Megan E. Rosa-Caldwell, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene Jul 2023

The Time-Course Of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions In Female Skeletal Muscle Distinct From Males, Francielly Morena, Seongkyun Lim, Ana Regina Cabrera, Eleanor R. Schrems, Ronald G. Jones, Megan E. Rosa-Caldwell, Tyrone A. Washington, Kevin A. Murach, Nicholas P. Greene

Health, Human Performance and Recreation Faculty Publications and Presentations

Background

Cancer-cachexia (CC) is a debilitating condition affecting up to 80% of cancer patients and contributing to 40% of cancer-related deaths. While evidence suggests biological sex differences in the development of CC, assessments of the female transcriptome in CC are lacking, and direct comparisons between sexes are scarce. This study aimed to define the time course of Lewis lung carcinoma (LLC)-induced CC in females using transcriptomics, while directly comparing biological sex differences.

Results

We found the global gene expression of the gastrocnemius muscle of female mice revealed biphasic transcriptomic alterations, with one at 1 week following tumor allograft and another …


Oropharyngeal Teratoma: Five-Month-Old Presenting With Failure To Thrive And Severe Obstructive Sleep Apnea., Anna Lawrence, Melissa Gener, Shao Jiang, Jill M. Arganbright Jul 2023

Oropharyngeal Teratoma: Five-Month-Old Presenting With Failure To Thrive And Severe Obstructive Sleep Apnea., Anna Lawrence, Melissa Gener, Shao Jiang, Jill M. Arganbright

Manuscripts, Articles, Book Chapters and Other Papers

Oropharyngeal teratomas are an extremely rare congenital tumor. They are often diagnosed prenatally and can cause significant airway obstruction and feeding difficulties at birth. We present a five-month-old female that was diagnosed with a palatal teratoma that presented with failure to thrive, difficulty feeding, and eventually with severe obstructive sleep apnea. We present a five-month-old term, otherwise healthy female who became stridulous after an episode of the respiratory syncytial virus at one month old. At three months old, an otolaryngologist diagnosed mild laryngomalacia with no mass identified, and no surgical intervention was recommended. Due to continued poor weight gain, at …


Effects Of Unilateral Eccentric Versus Concentric Training Of Nonimmobilized Arm During Immobilization, Trevor C. Chen, Shang-Hen Wu, Hsin-Lian Chen, Wei-Chin Tseng, Kuo-Wei Tseng, Hsing-Yu Kang, Kazunori Nosaka Jul 2023

Effects Of Unilateral Eccentric Versus Concentric Training Of Nonimmobilized Arm During Immobilization, Trevor C. Chen, Shang-Hen Wu, Hsin-Lian Chen, Wei-Chin Tseng, Kuo-Wei Tseng, Hsing-Yu Kang, Kazunori Nosaka

Research outputs 2022 to 2026

Introduction The present study tested the hypothesis that eccentric training (ET) of nonimmobilized arm would attenuate negative effects of immobilization and provide greater protective effects against muscle damage induced by eccentric exercise after immobilization, when compared with concentric training (CT). Methods Sedentary young men were placed to ET, CT, or control group (n = 12 per group), and their nondominant arms were immobilized for 3 wk. During the immobilization period, the ET and CT groups performed five sets of six dumbbell curl eccentric-only and concentric-only contractions, respectively, at 20%-80% of maximal voluntary isometric contraction (MVCiso) strength over six sessions. MVCiso …


The Origins Project Biobank: A Collaborative Bio Resource For Investigating The Developmental Origins Of Health And Disease, Nina D’Vaz, Courtney Kidd, Sarah Miller, Minda Amin, Jacqueline A. Davis, Zenobia Talati, Desiree T. Silva, Susan L. Prescott Jul 2023

The Origins Project Biobank: A Collaborative Bio Resource For Investigating The Developmental Origins Of Health And Disease, Nina D’Vaz, Courtney Kidd, Sarah Miller, Minda Amin, Jacqueline A. Davis, Zenobia Talati, Desiree T. Silva, Susan L. Prescott

Research outputs 2022 to 2026

Early onset Non-Communicable Diseases (NCDs), including obesity, allergies, and mental ill-health in childhood, present a serious and increasing threat to lifelong health and longevity. The ORGINS Project (ORIGINS) addresses the urgent need for multidisciplinary efforts to understand the detrimental multisystem impacts of modern environments using well-curated large-scale longitudinal biological sample collections. ORGINS is a prospective community birth cohort aiming to enrol 10,000 pregnant people and follow each family until the children reach 5 years of age. A key objective is to generate a comprehensive biorepository on a sub-group of 4000 families invited to contribute blood, saliva, buccal cells, urine, stool, …


Ers International Congress 2022: Highlights From The Thoracic Oncology Assembly, Maria J. Catarata, Wouter H. Van Geffen, Radhika Banka, Beatriz Ferraz, Calvin Sidhu, Alan Carew, Lucia Viola, Rolof Gijtenbeek, Georgia Hardavella Jul 2023

Ers International Congress 2022: Highlights From The Thoracic Oncology Assembly, Maria J. Catarata, Wouter H. Van Geffen, Radhika Banka, Beatriz Ferraz, Calvin Sidhu, Alan Carew, Lucia Viola, Rolof Gijtenbeek, Georgia Hardavella

Research outputs 2022 to 2026

Thoracic malignancies are associated with a substantial public health burden. Lung cancer is the leading cause of cancer-related mortality worldwide, with significant impact on patients’ quality of life. Following 2 years of virtual European Respiratory Society (ERS) Congresses due to the COVID-19 pandemic, the 2022 hybrid ERS Congress in Barcelona, Spain allowed peers from all over the world to meet again and present their work. Thoracic oncology experts presented best practices and latest developments in lung cancer screening, lung cancer diagnosis and management. Early lung cancer diagnosis, subsequent pros and cons of aggressive management, identification and management of systemic treatments’ …


The Mechanism Of Pda-Peg/Copper Selectively Killing Cancer Cells And Its Application In Treating Triple-Negative Breast Cancer And Advanced Ovarian Cancer, Xiangxiang Hu Jul 2023

The Mechanism Of Pda-Peg/Copper Selectively Killing Cancer Cells And Its Application In Treating Triple-Negative Breast Cancer And Advanced Ovarian Cancer, Xiangxiang Hu

Theses and Dissertations

Cancer is one of the leading modality diseases. The number of cancer patients has increased in the last decades due to radiation, aging, stress condition, and other reasons. There are three traditional cancer therapies (radiation therapy, chemotherapy, and surgery). Even though these treatments improve the life span of cancer patients, many cancer patients still lost their lives due to the development of tolerance. Thus, it is urgent to develop new kinds of treatments to extend the life span of patients. In recent decades, nanomedicine, which utilizes nanotechnology to deliver chemotherapy agents into tumor sites and improve the anticancer effect and …


The Impact Of Covid-19 On Psychosocial Services And Perceived Supports For Pediatric Patients, Samantha Martinez Jul 2023

The Impact Of Covid-19 On Psychosocial Services And Perceived Supports For Pediatric Patients, Samantha Martinez

Theses and Dissertations

In March 2020, the World Health Organization named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) a global pandemic. While the physiological damage of COVID-19 on individuals and communities is itself immeasurable, both because variants continue to spread and because of the unpredictable nature of “long COVID,” we know even less about the long-term psychological impacts on individuals. Lockdown procedures, including school closures, were necessary to prevent transmission of the virus and to protect the most vulnerable bodies (namely, the elderly and immuno-compromised). However, the effect of the closures disproportionately resulted in psychological damage to children and adolescents. Previous studies have …


Babe (Body Appreciation And Better Eating), Just Add A Dash Of Self-Compassion: A Randomized Controlled Pilot Study For Black/African American Teenage Girls, Nkechi Bianca Okpara Jul 2023

Babe (Body Appreciation And Better Eating), Just Add A Dash Of Self-Compassion: A Randomized Controlled Pilot Study For Black/African American Teenage Girls, Nkechi Bianca Okpara

Theses and Dissertations

Introduction

Body dissatisfaction contributes to disproportionately high rates of disordered eating behaviors observed in Black teenagers. Given that self-compassion is found to buffer against eating pathology and body dissatisfaction and is linked to reduced incidences of binge eating and disordered eating behavior. Incorporating the self-compassion construct, specifically centering on nutrition, with a program that combats negative body image, like the Body Project, may further help decrease body dissatisfaction and improve overall nutrition.

Purpose

The aim of this dissertation was to test (1) the acceptability and feasibility of a novel program, Body Appreciation and Better Eating, add self-compassion (BABE+SC), and to …