Medicine and Health Sciences Commons^™

Trauma-Related Shame Predicts Daily Non-Medical Prescription Opioid Use Among Individuals With Ptsd Symptoms, Tanya C. Saraiya, Alyssa C. Jones, Teresa Lopez-Castro, Caitlyn O. Hood, Jessica Flores, Christal L. Badour

UK CARES Faculty Publications

Non-medical prescription opioid use (NMPOU) is the use of opioids without a prescription or in a way different from how they were prescribed and is the fourth most common type of drug use in the United States. Separate research has shown that trauma-related shame is linked to posttraumatic stress disorder (PTSD) and, respectively, opioid use. However, no study to date has empirically examined the association between trauma-related shame and NMPOU among individuals with PTSD symptoms. Forty adults with clinical or subclinical PTSD who reported engaging in NMPOU at least one day in the prior month before the study completed 28 …

The Complexity Of Prn Psychotropic Medications In The Acute Care Setting, Morgan Pasquali Bsc Rn

Nurse Residency

PICOT Question: In the geriatric population who have PRN medication for agitation compared with those without PRN medication for agitation, are at risk for adverse events during their hospital stay?

Sulfamethoxazole-Trimethoprim Induced Thrombocytopenia: A Report Of Two Cases And A Literature Review, Leigh Griffin Dds, Michael Graffeo Dds, Jay Sher Dds, Paul D. Freedman Dds, Renée F. Reich

The New York State Dental Journal

Sulfamethoxazole- trimethoprim (ST) is a sulfonamide derivative antibiotic that interferes with bacterial folic acid synthesis and growth by blocking dihydrofolic acid formation from para-aminobenzoic acid. One of the potential side effects of sulfamethoxazole-trimethoprim is thrombocytopenia. Thrombocytopenia is a blood disorder characterized by a decreased number of circulating platelets. We present two cases of ST induced thrombocytopenia where the oral manifestations were the first indication of the low platelet count leading to life saving interventions. Our aim is to educate dentists about the oral manifestations of thrombocytopenia and its association with ST as their examination may be instrumental in directing treatment.

The Use Of Nitrous Oxide In Adult Inpatient Populations For Analgesic And Anxiety Management During Bedside Procedures, Avery Low Rn, Frances Brown Rn, Hannah Lewis Rn

Nurse Residency

PICOT question: In adult medical-surgical inpatient populations, how does nitrous oxide compared to commonly used pain medications, affect patient procedure compliance and/or experience, within the length of their hospital visit?

Post-Dural Puncture Headache, Children's Mercy Kansas City

Clinical Pathways (Formally Known As Care Process Models)

No abstract provided.

Assessing Psychometric Predictors Of Academic And Life Success For High School Students In A Stem-Based Program In Rural Alabama, Robin Bartlett, Alan Mckendall, Sherron Mckendall, Paige Johnson, Ann Chester

Faculty & Staff Scholarship

The Health Sciences and Technology Academy of Alabama (HSTA-AL) is an academic program focused on health sciences enrichment offered through the College of Nursing at the University of Alabama to address the state’s nursing and biomedical professionals shortage (i.e., a 10:1,000 nursing to population ratio). This paper examines outcomes addressing social, academic, and life success from the participants’ perspective. The one-sample-pretest-posttest designed study evaluated whether there was a difference between baseline and year 1 levels of community engagement and academic intentions for the 23 students for which paired data were obtained. Analyses show promising outcomes from baseline to year one …

Q2 Turns And Air Fluidized Therapy Beds, Fartun Hirsi Rn, Audrey Iradukunda Rn, Krissia Walker Rn

Nurse Residency

PICOT Question: How does repositioning patients every 2 hours compared to Air Fluidized therapy beds reduce the incidence of pressure injuries in critically immobile ill older adults?

The Benefits Of Heat Application And Range Of Motion Vs. Ice Therapy, Jared Proulx Rn Bsn, Alejandro Canales Rn

Nurse Residency

PICOT Question: In patients with musculoskeletal injuries, is heat application and gentle range of motion more or less effective than standard icing and immobilization methods in regard to the healing process, prognosis and positive patient outcomes?

Betamethasone And The Effects On Newborns Of Various Gestations, Julie Allen, Hanna Freeman, Kristina Smith

Nurse Residency

PICOT Question: In newborns of various gestational ages, how does administering betamethasone affect newborn outcomes within the first 72 hours of life?

Precision Of Metabolite-Selective Mrs Measurements Of Glutamate, Gaba And Glutathione: A Review Of Human Brain Studies., Kesavi Kanagasabai, Lena Palaniyappan, Jean Theberge

Department of Medicine Publications

Single-voxel proton magnetic resonance spectroscopy (SV 1 H-MRS) is an in vivo noninvasive imaging technique used to detect neurotransmitters and metabolites. It enables repeated measurements in living participants to build explanatory neurochemical models of psychiatric symptoms and testing of therapeutic approaches. Given the tight link among glutamate, gamma-amino butyric acid (GABA), glutathione and glutamine within the cellular machinery, MRS investigations of neurocognitive and psychiatric disorders must quantify a network of metabolites simultaneously to capture the pathophysiological states of interest. Metabolite-selective sequences typically provide improved metabolite isolation and spectral modelling simplification for a single metabolite at a time. Non-metabolite-selective sequences provide …

Timing Of Decompressive Surgery In Patients With Acute Spinal Cord Injury: Systematic Review Update, Michael Fehlings, Laureen Hachem, Lindsay Tetreault, Andrea Skelly, Joseph Dettori, Erika Brodt, Shay Stabler-Morris, Britt Redick, Nathan Evaniew, Allan Martin, Benjamin Davies, Farzin Farahbakhsh, James Guest, Daniel Graves, Radha Korupolu, Stephen Mckenna, Brian Kwon

Department of Rehabilitation Medicine Faculty Papers

STUDY DESIGN: Systematic review and meta-analysis.

OBJECTIVE: Surgical decompression is a cornerstone in the management of patients with traumatic spinal cord injury (SCI); however, the influence of the timing of surgery on neurological recovery after acute SCI remains controversial. This systematic review aims to summarize current evidence on the effectiveness, safety, and cost-effectiveness of early (≤24 hours) or late (>24 hours) surgery in patients with acute traumatic SCI for all levels of the spine. Furthermore, this systematic review aims to evaluate the evidence with respect to the impact of ultra-early surgery (earlier than 24 hours from injury) on these …

A Novel System To Culture Human Intestinal Organoids Under Physiological Oxygen Content To Study Microbial-Host Interaction, Tatiana Y. Fofanova, Umesh C. Karandikar, Jennifer M. Auchtung, Reid L. Wilson, Antonio J. Valentin, Robert A. Britton, K. Jane Grande-Allen, Mary K. Estes, Kristi Hoffman, Sashirekha Ramani, Christopher J. Stewart, Joseph F. Petrosino

Food for Health: Publications

Mechanistic investigation of host-microbe interactions in the human gut are hindered by difficulty of co-culturing microbes with intestinal epithelial cells. On one hand the gut bacteria are a mix of facultative, aerotolerant or obligate anaerobes, while the intestinal epithelium requires oxygen for growth and function. Thus, a coculture system that can recreate these contrasting oxygen requirements is critical step towards our understanding microbial-host interactions in the human gut. Here, we demonstrate Intestinal Organoid Physoxic Coculture (IOPC) system, a simple and cost-effective method for coculturing anaerobic intestinal bacteria with human intestinal organoids (HIOs). Using commensal anaerobes with varying degrees of oxygen …

Handoff Report & Standardizing Report Sheets, Isabella Santeramo Rn Adn, Caitlin Salas Rn Adn, Samantha Neilhart Rn Adn, Debra Harmon Rn Adn

Nurse Residency

PICOT Question: In nursing, how does a standardized report compared to a non-standardized report affect efficiency in continuity of care in a 12-hour shift?

Dentistry And The Law: Charges For Missed Appointments And Interest On Past-Due Accounts, Dan Schulte Jd

The Journal of the Michigan Dental Association

This month’s Dentistry and the Law column explores the legal considerations surrounding charges for missed appointments and interest on past-due accounts in dental practices. Dan Schulte, JD, provides insights on implementing policies for collecting patient deposits for missed appointments and the legality of charging interest on overdue accounts. The article emphasizes the importance of complying with participation agreements, obtaining patient consent, and setting reasonable terms. Practical guidelines for policy implementation are provided, ensuring dental practitioners navigate legal complexities while managing practice finances effectively.

Severe Ataxia With Cognitive Impairment In A Young Child: A Case Report Of Pontocerebellar Hypoplasia, Soban Khan, Zeeshan Munawar, Zaid Waqar, Saad Ali, Bushra Khalid, Amina Sadiqa, Mazhar Badshah

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT

Adolescence is a period of rapid development and a variety of genetic disorders present during this time due to difficulties with motor and cognitive skills. A very rare group of diseases is genetic Pontocerebellar Hypoplasia, characterized by a developmentally small cerebellum that leads to ataxia and movement abnormalities. Here, we present a case of a young boy who presented with ataxia and falls.

Age-Stratified Mosaic Of Neuropathies: A Comprehensive Analysis Of The Prevalence And Patterns In Different Age Groups, Sana Ghous, Anjlee Shankar, Abdul Qadir Baloch, Dipanty Khastoori, Tahira Maqsood, Alam Ibrahim Siddiqui

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT

Background and Objective:

Neuropathies pose significant challenges in diagnosis and management due to their heterogeneous etiologies, varied clinical presentations, and differential prevalence across age groups. The objective of this study was to analyze the distribution of neuropathies among patients in various age brackets, highlighting prevalent neuropathic types and their clinical implications.

Methods:

From September 18, 2018 to September 17, 2019, 405 patients from Neurology Ward of Chandka Medical College Hospital in Larkana were included in this retrospective cross-sectional comprehensive analysis. Nerve conduction studies (NCS) of these patients were conducted in the electrophysiology department. The study cohort was stratified into …

Effects Of Maternal Subclinical Hypothyroidism On Neurodevelopment Of Offspring- An Animal-Based Study, Sabah Farhat, Syeda Sadia Fatima, Mehir Un Nisa Iqbal, Fazal Arain

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT

Background and objective:

Maternal subclinical hypothyroidism (SCH) during pregnancy is associated with adverse maternal and neonatal outcomes, including cognitive and neuropsychiatric effects. This study aimed to assess the impact of maternal SCH on young rats, examining behavioral and gross brain structure changes, and evaluating reversibility after levothyroxine treatment.

Methods:

This experimental animal study was conducted at the Aga Khan University for a duration of 10 months. The study was approved by the Ethical committee for Animal Care and Use. Fourteen female Sprague Dawley rats were grouped into Treated (induced with SCH, treated with levothyroxine), Untreated (induced with SCH, no …

Use Of The 0.3-Tesla Mri Machine In Pakistan For Neurological Disorders In The Current Era: A Necessary Compromise Or A Counterproductive Exercise?, Wajid Jawaid

Pakistan Journal of Neurological Sciences (PJNS)

No abstract provided.

Beyond The Mosquito Sting: Guillain-Barre Syndrome Following Malarial Seasonal Surge, Sana Ghous, Alam Ibrahim Siddiqui, Abdul Rahman Soomro, Abu Bakar Shaikh, Sajjad Hussain Jalbani, Abdul Ghafoor Magsi

Pakistan Journal of Neurological Sciences (PJNS)

ABSTRACT

Background and objective:

Malaria, a prevalent disease most commonly caused by Plasmodium vivax and falciparum, frequently leads to intricate neurological complications. The objective of this study was to study Guillain-Barre syndrome as a prevalent neurological manifestation of malaria.

Methods:

A cross-sectional observational study was undertaken at Neurology Department of Chandka Medical College Hospital in Larkana, from April 2023 to September 2023 during the seasonal peak of malaria. The study included 20 patients who met the specified criteria. SPSS version 23.0 was used for data analysis.

Results:

Among the 20 patients who developed Guillain-Barre Syndrome following malaria infection, 18 exhibited …

Nursing News & Views - March 2024, Joanne Miller Rn

Nursing Newsletters

No abstract provided.

Interventions To Optimize Spinal Cord Perfusion In Patients With Acute Traumatic Spinal Cord Injury: An Updated Systematic Review, Nathan Evaniew, Benjamin Davies, Farzin Farahbakhsh, Michael G. Fehlings, Mario Ganau, Daniel E. Graves, James D. Guest, Radha Korupolu, Allan R. Martin, Stephen L. Mckenna, Lindsay A. Tetreault, Aditya Vedantam, Erika D. Brodt, Andrea C. Skelly, Brian K. Kwon

Department of Rehabilitation Medicine Faculty Papers

STUDY DESIGN: Systematic review update.

OBJECTIVES: Interventions that aim to optimize spinal cord perfusion are thought to play an important role in minimizing secondary ischemic damage and improving outcomes in patients with acute traumatic spinal cord injuries (SCIs). However, exactly how to optimize spinal cord perfusion and enhance neurologic recovery remains controversial. We performed an update of a recent systematic review (Evaniew et al, J. Neurotrauma 2020) to evaluate the effects of Mean Arterial Pressure (MAP) support or Spinal Cord Perfusion Pressure (SCPP) support on neurological recovery and rates of adverse events among patients with acute traumatic SCI.

METHODS: We …

An Umbrella Review Of Self-Management Interventions For Health Conditions With Symptom Overlap With Traumatic Brain Injury, Angelle Sander, Monique Pappadis, Tamara Bushnik, Nancy Chiaravalloti, Simon Driver, Robin Hanks, Kirk Lercher, Dawn Neumann, Amanda Rabinowitz, Ronald T Seel, Erica Weber, Rick Ralston, John Corrigan, Kurt Kroenke, Flora Hammond

Department of Rehabilitation Medicine Faculty Papers

OBJECTIVE: To synthesize evidence for the effectiveness of self-management interventions for chronic health conditions that have symptom overlap with traumatic brain injury (TBI) in order to extract recommendations for self-management intervention in persons with TBI.

DESIGN: An umbrella review of existing systematic reviews and/or meta-analyses of randomized controlled trials or nonrandomized studies targeting self-management of chronic conditions and specific outcomes relevant to persons with TBI.

METHOD: A comprehensive literature search of 5 databases was conducted using PRISMA guidelines. Two independent reviewers conducted screening and data extraction using the Covidence web-based review platform. Quality assessment was conducted using criteria adapted from …

Wastewater Surveillance For Identifying Sars-Cov-2 Infections In Long-Term Care Facilities, Kentucky, Usa, 2021–2022, James W. Keck, Reuben Adatorwovor, Matthew Liversedge, Blazan Mijotavich, Cullen Olsson, William D. Strike, Atena Amirsoleimani, Ann Noble, Soroosh Torabi, Alexus Lori Rockward, Mohammad Dehghan Banadaki, Ted Smith, Parker Lacy, Scott M. Berry

UK CARES Faculty Publications

Persons living in long-term care facilities (LTCFs) were disproportionately affected by COVID-19. We used wastewater surveillance to detect SARS-CoV-2 infection in this setting by collecting and testing 24-hour compos- ite wastewater samples 2–4 times weekly at 6 LTCFs in Kentucky, USA, during March 2021–February 2022. The LTCFs routinely tested staff and symptomatic and exposed residents for SARS-CoV-2 using rapid antigen tests. Of 780 wastewater samples analyzed, 22% (n = 173) had detectable SARS-CoV-2 RNA. The LTCFs reported 161 positive (of 16,905) SARS-CoV-2 clinical tests. The wastewater SARS-CoV-2 signal showed vari- able correlation with clinical test data; we observed the strongest …

Manufacturing Supported Loose-Nanofiltration Polymeric Membranes With Eco-Friendly Solvents On An R2r System, David Lu, Kwangjun Jung, Ju Young Shim, Tequila A. L. Harris, Isabel Escobar

UK CARES Faculty Publications

In this study, loose nanofiltration membranes made of polysulfone dissolved in co-solvents PolarClean and gamma-Valerolactone were prepared via slot die coating (SDC) on a roll-to-roll (R2R) system by directly coating them onto a support layer or free standing. A solution flow rate of 20 mL/min, substrate speed of 17.1 mm/s, and coating gap of 0.1 mm resulted in the formation of membranes without structural defects. Pre-wetting the support layer with dope solution minimized shrinkage of membrane layer thickness and improved interfacial adhesion. Membrane samples produced using SDC exhibited properties and performance consistent with bench-scale doctor blade extruded samples; pre-wetted and …

Western Maine Addiction And Recovery Initiative's Substance Misuse Prevention And Wellness Day: Year 2 Planning Survey Summary For Ohchs, Evelyn Ali Bs, Tyler Egeland Ba, Mary Lindsey Smith Phd

Substance Use Research & Evaluation

The RCORP local evaluation team at the Catherine Cutler Institute deployed a survey to Oxford Hills Comprehensive High School (OHCHS). The purpose of the survey was to understand needs unique to OHCHS to plan for types of activities and information presented at the school’s Substance Use Prevention and Wellness Day. For more information, please contact Lindsey Smith at [email protected]

Nail-Plate Combination Treatment Of Ipsilateral Humeral Shaft And Distal Humerus Fractures - A Case Report., Mark Lagreca, Yash P Chaudhry, Thomas Falconiero, Thomas Muzzonigro, Daniel Lippe, Mitesh Shah

Orthopedic Surgery Resident Research

INTRODUCTION: Humeral shaft and distal humerus fractures have several different treatment options, including plate fixation and intramedullary nailing. Each has its own benefits, but typically, they are not used in conjunction. While nail-plate combinations (NPCs) have become more common in the lower extremity, literature on their use in upper extremity fractures remains scarce.

CASE REPORT: A 74-year-old right-hand dominant male presented after a fall with a closed left transverse midshaft humerus fracture and an associated supracondylar distal humerus fracture with intercondylar extension through a medial column. Due to the segmental nature of his injury, medial column plating was used in …

Improving Sexual Health Through Medical Education, Renee J Flores

Faculty and Staff Publications

No abstract provided.

Identification Of The Pan‑Allergen Tropomyosin From The Common Bed Bug (Cimex Lectularius), Johnalyn Gordon, Zachary C. Devries

UK CARES Faculty Publications

Tropomyosin is a muscle contraction protein documented across all animal life. Despite its ubiquity, its unique structure in invertebrates leads to allergic responses in humans that vertebrate tropomyosin does not. High degrees of homology can explain cross‑reactivity between tropomyosin derived from distantly‑related arthropod species and establishes tropomyosin as a panallergen. Given this cross‑ reactivity and that they are commonly found in high numbers indoors, research on the potential of the common bed bug (Cimex lectularius L.) to contribute tropomyosin to the indoor environment is needed. Therefore, we investigated tropomyosin homology between bed bugs and known tropomyosin allergens from other taxa, …

Navigating Through Chaos, Hoong Chuin Lau

Asian Management Insights

How AI and optimisation models can strengthen supply chain resilience.

“No Matter How Hot It Is, You Just Have To Do The Work”: Examining Farmworkers’ Experiences With Heat And Climate Change In Idaho, Carly Hyland, Delmy Flores, Grace Augusto, Irene Ruiz, Marielena Vega, Rulon Wood

Public and Population Health Faculty Publications and Presentations

Introduction: Farmworkers are one of the populations most vulnerable to climate change. In addition to disproportionate exposure to climate-intensified hazards such as extreme heat and wildfire smoke, many farmworkers face situational and psychosocial stressors that also impact their health.

Methods: We conducted open-ended interviews with 16 farmworkers in Southcentral Idaho during June-August 2023 as part of a digital storytelling project in partnership with the Idaho Organization of Resource Councils (IORC). Interviews assessed participants’ experiences with climate change, perceived impacts on their health, and strategies and barriers to protecting themselves. Bilingual (English/Spanish) study staff translated and transcribed all video recordings verbatim, …