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Articles 40411 - 40440 of 325328
Full-Text Articles in Medicine and Health Sciences
Exploring The Role Of Yoga In Improving The Quality Of Life Among Patients Diagnosed With Schizophrenia And Intellectual Disability, Laura Tolbaños-Roche
Exploring The Role Of Yoga In Improving The Quality Of Life Among Patients Diagnosed With Schizophrenia And Intellectual Disability, Laura Tolbaños-Roche
Journal of Applied Yoga Studies
Background and objectives
There is large evidence of the positive effect of yoga in mental health disorders, mainly anxiety and depression. However, the studies on the role of yoga in schizophrenia and intellectual disability are sparse and inconclusive. The objective of this study is exploring the role of a specific yoga intervention, based on the Gitananda Rishiculture Asthanga Yoga Tradition, in improving the quality of life (QoL) of patients diagnosed with schizophrenia and intellectual disability in a mental health institution of Las Palmas de Gran Canaria (Spain).
Methods
Patients diagnosed with schizophrenia (n=5) and patients diagnosed with intellectual disability (n=4) …
Editors' Note, Dr. Lori Rubenstein Fazzio, Dr. Meena Ramanathan, Dr. Praseeda Menon
Editors' Note, Dr. Lori Rubenstein Fazzio, Dr. Meena Ramanathan, Dr. Praseeda Menon
Journal of Applied Yoga Studies
Welcome message from the editors.
Noda News December 2024
New Orleans Dental Association News
New Orleans Dental Association (NODA) News includes regular columns with regional news impacting the New Orleans membership including: columns from the President and Executive Director, feature articles relating to the field of dentistry, association events and upcoming activities, component news, continuing education opportunities, and classifieds.
Random Blood Glucose As An Alternative To Glycated Hemoglobin For Assessing Glycemic Control In Diabetes Mellitus Patients. Cross-Sectional Study In Babylon Province, Iraq, Hajir Karim Abdul-Husseein, Abeer Tariq Watife, Mustafa Karim Abdul-Husseein, Hayder Abdul-Amir Makki Al-Hindy, Karam Akram Al- Akkam
Random Blood Glucose As An Alternative To Glycated Hemoglobin For Assessing Glycemic Control In Diabetes Mellitus Patients. Cross-Sectional Study In Babylon Province, Iraq, Hajir Karim Abdul-Husseein, Abeer Tariq Watife, Mustafa Karim Abdul-Husseein, Hayder Abdul-Amir Makki Al-Hindy, Karam Akram Al- Akkam
Maaen Journal for Medical Sciences
Background: Diabetes affected 171 million people worldwide one and a half decades ago, and 366 million people are expected by 2030. The relationship between glycated hemoglobin (HbA1c) and diabetes complications was established, emphasizing the importance of good glycemic management. However, due to its high cost, the HbA1c test is considered to be not affordable or not available. The high incidence of diabetes mellitus (DM) and its more risky comorbidities in most populations necessitate the requirement for regarding an alternative test.
Objective: The aim of the current study was to assess if there is a relationship between HbA1c and …
6th Annual Occupational Therapy Program Research Conference, Kelly L. Taylor Otd, Ms, Otr/L, Cbis
6th Annual Occupational Therapy Program Research Conference, Kelly L. Taylor Otd, Ms, Otr/L, Cbis
Student Scholarship & Creative Works
Occupational Therapy Program RESEARCH CONFERENCE
6TH OT COHORT | CLASS OF 2025
OT Program Student Presentations Graduate Students from the Class of 2025
Sk609, A Novel Dopamine D3 Receptor Agonist And Norepinephrine Transporter Blocker With Putative Pro-Cognitive Actions, Does Not Induce Psychostimulant-Like Increases In Risky Choice During Probabilistic Discounting, Christopher P. Knapp, Brooke Fallon, Sandhya Kortagere, Barry D. Waterhouse, Stan B Floresco, Rachel L Navarra
Sk609, A Novel Dopamine D3 Receptor Agonist And Norepinephrine Transporter Blocker With Putative Pro-Cognitive Actions, Does Not Induce Psychostimulant-Like Increases In Risky Choice During Probabilistic Discounting, Christopher P. Knapp, Brooke Fallon, Sandhya Kortagere, Barry D. Waterhouse, Stan B Floresco, Rachel L Navarra
Rowan-Virtua School of Osteopathic Medicine Departmental Research
RATIONALE: Psychostimulants, such as amphetamine (AMPH) and methylphenidate (MPH), non-selectively elevate extracellular concentrations of the catecholamine neurotransmitters, dopamine (DA) and norepinephrine (NE), and are common pharmacological strategies used to improve prefrontal cortex (PFC)-dependent cognitive dysfunction. However, this approach can be problematic given AMPH has been shown to increase preference for risky choices in a rodent assay of risk/reward decision making. SK609 is a novel NE reuptake blocker that selectively activates DA D3 receptors without affinity for the DA transporter. SK609 has been shown to improve cognitive performance without increasing psychostimulant-like spontaneous locomotor activity, suggesting SK609 may benefit neurocognitive function without …
Impact Of Patient Psychoeducation On Medication Adherence In Bipolar Depression, Mary Nse Wellington
Impact Of Patient Psychoeducation On Medication Adherence In Bipolar Depression, Mary Nse Wellington
Walden Dissertations and Doctoral Studies
The quality improvement (QI) project targeted patients with bipolar depression, aged 20–50 years, in an outpatient mental health setting who had the problem of nonadherence to medication. Medication nonadherence is a major concern in nursing practice that impacts clinical effectiveness, overall treatment outcomes, and healthcare cost implications. The project evaluated whether the outcome, timely refill rates of prescription medication, was impacted by the psychoeducation that was conducted outside the scope of the project. The project question was, “What is the impact of patient psychoeducation to improve timely refill rates among patients with bipolar depression aged 20–50 years in an outpatient …
Perceptions And Attitudes Of Western Michigan University Students On Antibiotic Medications, Emily Boask
Perceptions And Attitudes Of Western Michigan University Students On Antibiotic Medications, Emily Boask
Honors Theses
On a global scale, antibiotic resistance is a threat to public health. The causes of antibiotic resistance are multifaceted, including healthcare providers overprescribing antibiotics, antibiotic overuse in farming and food production, and antibiotic misuse or malpractices. The public recognizes antibiotic resistance as a significant problem but there are serious knowledge gaps regarding antibiotic resistance and antibiotic stewardship.
University students are a particularly important subpopulation of the public to understand appropriate antibiotic use because many of these individuals are navigating their health concerns on their own for the first time. Many individuals believe that antibiotics can improve cold symptoms, upper respiratory …
Interaction Between Type 2 Diabetes And Past Covid-19 On Active Tuberculosis, Liz E. Calles-Cabanillas, Genesis P. Aguillón-Durán, Doris Ayala, Jose A. Caso, Miguel Garza, Mateo Joya-Ayala, Raúl Loera-Salazar, America Cruz-González, John M. Thomas Iii, Blanca I. Restrepo
Interaction Between Type 2 Diabetes And Past Covid-19 On Active Tuberculosis, Liz E. Calles-Cabanillas, Genesis P. Aguillón-Durán, Doris Ayala, Jose A. Caso, Miguel Garza, Mateo Joya-Ayala, Raúl Loera-Salazar, America Cruz-González, John M. Thomas Iii, Blanca I. Restrepo
School of Medicine Publications
Background
The global setback in tuberculosis (TB) prevalence and mortality in the post-COVID-19 era has been partially attributed to pandemic-related disruptions in healthcare systems. The additional biological contribution of COVID-19 to TB is less clear. The goal of this study was to determine if there is an association between COVID-19 in the past 18 months and a new TB episode, and the role played by type 2 diabetes mellitus (DM) comorbidity in this relationship.
Methods
A cross-sectional study was conducted among 112 new active TB patients and 373 non-TB controls, identified between June 2020 and November 2021 in communities along …
Age-Related Differences In Behavioral Outcomes Of Bimanual Functional Motor Tasks In Children And Adolescents With Cerebral Palsy: A Scoping Review, Hubert D. Gascon, Sahian Alicia Maldonado Numata, Sandrine Emond, Samuel Nemanich, Maxime T. Robert
Age-Related Differences In Behavioral Outcomes Of Bimanual Functional Motor Tasks In Children And Adolescents With Cerebral Palsy: A Scoping Review, Hubert D. Gascon, Sahian Alicia Maldonado Numata, Sandrine Emond, Samuel Nemanich, Maxime T. Robert
Occupational Therapy Faculty Research and Publications
Aim: The objective of this review is to determine age-related differences in behavioral outcomes of bimanual motor tasks in children and adolescents with cerebral palsy (CP). Method: This review followed the 6-stage Joanna Briggs institute methodology. The embase, EBSCO CINAHL, and PubMed databases were searched on May 2024. we included studies that employed instrumented measures to assess bimanual tasks in individuals with CP aged between 3 and 19 years.Results: Twenty-eight studies were included after full-text screening. This review reported on 544individuals with CP. Bimanual tasks were grouped in seven categories and their varying complexities were listed and analyzed. There are …
The Implementation Of Ketamine-Assisted-Psychotherapy On Healthcare Workers Suffering From Workplace-Related Ptsd Due To Covid-19, Ziluolan Zou
Nursing | Student Research Posters
During the coronavirus disease 2019 (COVID-19) pandemic, healthcare workers were exposed to a deadly disease with limited knowledge and personal protective equipment, subjected to long hours, forced to ration care due to limited critical care resources and ventilators, and isolated from their families due to fear of spreading the virus. These factors further compounded the occupational stress associated with being a healthcare worker. The literature shows that the physical, mental, and emotional challenges frontline healthcare workers faced during the COVID-19 pandemic had lasting impacts on their mental health. The prevalence of mental health illnesses, such as post-traumatic stress disorder, among …
Robotics And A.I In Oncological Surgery, Ian Ngo
Robotics And A.I In Oncological Surgery, Ian Ngo
Nursing | Student Research Posters
Throughout the decades, advancements in
technology have been surpassing limits that
were thought impossible. Every day these
breakthroughs are improving modern
surgery whether it be enhancing precision
on surgical sites, increasing accuracy of
procedure, or reducing recovery rates for
patients. Among the newly increasing
innovations, the implementation of robotics
systems and artificial intelligence (AI) into
the surgical field has emerged into
becoming a transformative force, especially
within a context as delicate as tumor removal.
This study explores the numerous benefits
of incorporating robotics and artificial
intelligence (AI) in tumor removal surgeries.
We investigate how these innovations
improve surgical accuracy, reduce …
The Effects Of Music Therapy On Pediatric Patients With Congenital Heart Defects In The Pre And Postoperative Setting, Janelle Marie Choy
The Effects Of Music Therapy On Pediatric Patients With Congenital Heart Defects In The Pre And Postoperative Setting, Janelle Marie Choy
Nursing | Student Research Posters
Congenital heart defects is a prominent medical occurrence especially in pediatrics. These defects often require surgeries and extensive treatment plans. These treatment plans often include invasive surgeries and extensive treatment plans which can require long recovery times along with potential surgical complications. This study aims to evaluate the effectiveness of music therapy on pediatric patients with congenital heart defects in the pre and postoperative setting and how music therapy can be implemented in treatment plans to yield effective recovery results for these patients. This research is significant as elevated vital signs and preoperative anxiety are associated with an increased need …
Educational Program On Depression And Anxiety For Low Socioeconomic Postpartum Latina Mothers, Lizbeth Valdez Duran
Educational Program On Depression And Anxiety For Low Socioeconomic Postpartum Latina Mothers, Lizbeth Valdez Duran
Nursing | Student Research Posters
Postpartum depression (PPD) and postpartum anxiety are common mental health conditions that women experience after childbirth. PPD involves intense feelings of extreme sadness, and diminished interests in activities that once brought them happiness. Postpartum anxiety involves constant worry and fear, often centered on the well-being of the baby. Symptoms may include restlessness or irritability, panic attacks, and trouble concentrating or sleeping. Barriers to treating depression and anxiety among Latinas include a lack of awareness or understanding of mental health issues. (Lopez et al., 2018).
Health Literacy refers to the individual's ability to understand and process health-related information. By assessing a …
Prepared To Protect: Improving Cardiac Emergency Response In Youth Club Sports, Melissa Garcia
Prepared To Protect: Improving Cardiac Emergency Response In Youth Club Sports, Melissa Garcia
Nursing | Student Research Posters
Sudden cardiac arrest (SCA) is a medical emergency where the heart unexpectedly stops beating due to an electrical malfunction. A person experiencing a cardiac arrest collapses, loses consciousness, and ceases breathing (American Heart Association, 2022).
Exercise offers numerous benefits to the cardiovascular system and a person’s overall health. However, there are incidents of sports-related cardiac arrest in apparently healthy athletes, including children and young adults. Athletes may be exposed to dehydration, adrenic surges, electrolyte imbalances, acid/base disturbances, and trauma which increases their risk of experiencing a cardiac event (Wasfy et al., 2016).
Sudden cardiac arrest is the leading cause of …
Racial Concordance Perceptions Of Post-Op African-American Patients, John-Ezekiel Moya
Racial Concordance Perceptions Of Post-Op African-American Patients, John-Ezekiel Moya
Nursing | Student Research Posters
African-Americans have historically faced significant health disparities, which persist due to implicit racial biases and a lack of cultural competency among non-Black healthcare providers. These disparities often result in poorer health outcomes and diminished patient satisfaction. One potential factor in mitigating these issues is racial concordance, the alignment of racial identity between patients and providers (Jetty et al., 2022). However, only 6.3% of the nursing workforce identifies as Black or African-American (Smiley et al., 2023), limiting opportunities for racially concordant care. While racial concordance may foster trust, communication, and comfort in healthcare settings, research on its importance to African-American Patients—especially …
Telogen Effluvium Incidence In Women Wearing Hijab Compared To Non-Hijab: A Cross-Sectional Study, Sondang Pandjaitan Sirait, Sandra Widaty, Lili Legiawati, Lis Surachmiati Suseno, Roro Inge Ade Krisanti, Windy Keumala Budianti, Eliza Miranda, Rahadi Rihatmadja, Caroline Oktarina, Paulus Anung Anindita Pandelaki, Irhen Situmeang
Telogen Effluvium Incidence In Women Wearing Hijab Compared To Non-Hijab: A Cross-Sectional Study, Sondang Pandjaitan Sirait, Sandra Widaty, Lili Legiawati, Lis Surachmiati Suseno, Roro Inge Ade Krisanti, Windy Keumala Budianti, Eliza Miranda, Rahadi Rihatmadja, Caroline Oktarina, Paulus Anung Anindita Pandelaki, Irhen Situmeang
Journal of General - Procedural Dermatology and Venereology Indonesia
Background: Hair loss is a normal experience, but if the amount of hair loss exceeds what is considered normal, it will usually cause anxiety for the patient. In Indonesia, almost every Muslim woman wears a hijab. The hijab is one of many factors believed to cause hair loss. Telogen effluvium (TE) itself is a hair cycle disorder in which the anagen phase terminates prematurely, resulting in diffuse club hair loss without scarring, and TE itself has many risk factors. The purpose of this study was to determine the relationship between the incidence of TE in women who wear hijabs …
Accuracy In Measurement Of Infant Formula Powder And Water With And Without A Crying Baby Present, Richard R. Rosenkranz, Chris Acosta, Ana Gonzalez-Alvarez, Andrew Hooyman, Jose R. Hidalgo, Romina Ballasteros-Paniagua, Sara K. Rosenkranz
Accuracy In Measurement Of Infant Formula Powder And Water With And Without A Crying Baby Present, Richard R. Rosenkranz, Chris Acosta, Ana Gonzalez-Alvarez, Andrew Hooyman, Jose R. Hidalgo, Romina Ballasteros-Paniagua, Sara K. Rosenkranz
Physical Therapy Faculty Articles and Research
"
Infant formula provides a safe, nutritious alternative to breastfeeding but caregivers may use unsanitary methods or make substantial errors with formula dilution and jeopardize infant health.1 Underdiluting formula can result in health problems, such as hypernatremic dehydration, gastroenteritis, other digestive problems, or long-term excess weight gain.2 Overdiluting infant formula, sometimes used to reduce expense by low-income caregivers,2 can also lead to serious health problems for babies, including diarrhea, water intoxication, nutrient deficiencies, malnutrition, and even death.2,3
Previous studies have assessed common measurement inaccuracy of infant formula preparations in relation to bottle characteristics, package instructions, caregiver experience, and target amount, …
Multicenter Clinical Performance Evaluation Of The Neumodx™ Ct/Ng Assay 2.0, B. Van Der Pol, A. Avery, Stephanie N. Taylor, J. Miller, C. L. Emery, A. English, G. B. Lazenby, Rebecca Lillis, J. Ruth, D. Young, S. Young, S. Chavoustie, L. Crane, V. Reid, G. Wall, S. Johnson
Multicenter Clinical Performance Evaluation Of The Neumodx™ Ct/Ng Assay 2.0, B. Van Der Pol, A. Avery, Stephanie N. Taylor, J. Miller, C. L. Emery, A. English, G. B. Lazenby, Rebecca Lillis, J. Ruth, D. Young, S. Young, S. Chavoustie, L. Crane, V. Reid, G. Wall, S. Johnson
School of Medicine Faculty Publications
Background: Given the continued increases in rates of both Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG) infection, additional diagnostic assays may be useful in increasing access to testing for these sexually transmitted infections. We evaluated the performance of the NeuMoDx™ CT/NG Assay 2.0 on the NeuMoDx-96 and NeuMoDx-288 Molecular Systems. Methods: The clinical sensitivity and specificity of the assay was assessed when used with: 1) endocervical swabs; 2) self-, and clinician-collected vaginal swabs; and 3) first-catch urine specimens (female and male). Results were compared to a patient infection status based on US Food and Drug Administration (FDA)-cleared assays. Results: The …
A Review Of The Association Between Dietary Intake And Brain Iron Levels In Older Adults: Preliminary Findings And Future Directions., Valentinos Zachariou, Christopher E. Bauer, Colleen A. Pappas, Brian T. Gold
A Review Of The Association Between Dietary Intake And Brain Iron Levels In Older Adults: Preliminary Findings And Future Directions., Valentinos Zachariou, Christopher E. Bauer, Colleen A. Pappas, Brian T. Gold
Behavioral Science Faculty Publications
Background/Objectives: Non-heme iron is essential for critical neuronal functions such as ATP generation, synaptogenesis, neurotransmitter synthesis, and myelin formation. However, as non-heme iron accumulates with age, excessive levels can contribute to oxidative stress, potentially disrupting neuronal integrity and contributing to cognitive decline. Despite growing evidence linking high brain iron with poorer cognitive performance, there are currently no proven methods to reduce brain iron accumulation in aging or to protect cognitive function from iron’s negative effects. Recent studies suggest that nutrition may influence brain iron levels, though the evidence remains limited and mixed. Methods: In this review, we explore recent findings, …
A Prospective Study In The Treatment Of Androgenic Alopecia Using Combination Of Procapil, Capixyl, Redensyl, Garima Bansal, Rishi Bansal
A Prospective Study In The Treatment Of Androgenic Alopecia Using Combination Of Procapil, Capixyl, Redensyl, Garima Bansal, Rishi Bansal
Journal of General - Procedural Dermatology and Venereology Indonesia
Background: Androgenic alopecia is characterized by its diffuse loss and the miniaturization of the hair. The study aimed to assess the safety and efficacy of procapil, redensyl, capixyl, bicapil, and anagain in topical hair growth serum in androgenic alopecia.
Methods: A prospective study was conducted on 110 healthy subjects aged 18-60 with androgenic alopecia in the Department of Dermatology, Tundla, Etmadhpur. Each subject applied 1 ml of serum on a dry scalp and was followed up on the 4th, 8th, 12th, and 16th week. Mean, median, and standard deviation were calculated. A repeated measure …
Virtual Primary Care In A Large Delaware-Based Independent Academic Medical Center: Impact And Opportunity, Darrell C. Dow, Sarah E. Schenck, Tracy L. Bell, Stephanie C. Roth, Omar Khan
Virtual Primary Care In A Large Delaware-Based Independent Academic Medical Center: Impact And Opportunity, Darrell C. Dow, Sarah E. Schenck, Tracy L. Bell, Stephanie C. Roth, Omar Khan
Department of Family & Community Medicine Faculty Papers
COVID-19 and related challenges to patient access necessitated the development of new models of care to ensure a healthy patient population. This paper describes the outcomes of a pilot virtual primary care program at a large independent academic health center in Delaware. The preliminary results are encouraging from the perspective of provider and patient satisfaction, as well as the utility of the operational model. A complete cost-benefit analysis was beyond the scope of the paper; thus, future operational research should focus on the metrics of cost and quality as key indicators of model sustainability.
30- And 90-Day Readmission Rates Following Traumatic Spinal Cord Injury: A Systematic Review And Meta-Analyses, Marjan Hesari, Seyed Danial Alizadeh, Hamid Malekzadeh, Reza Tabrizi, Mohammad-Rasoul Jalalifar, Alireza Shahmohammadi, Zahra Eskandari, Zahra Ghodsi, James Harrop, Vafa Rahimi-Movaghar
30- And 90-Day Readmission Rates Following Traumatic Spinal Cord Injury: A Systematic Review And Meta-Analyses, Marjan Hesari, Seyed Danial Alizadeh, Hamid Malekzadeh, Reza Tabrizi, Mohammad-Rasoul Jalalifar, Alireza Shahmohammadi, Zahra Eskandari, Zahra Ghodsi, James Harrop, Vafa Rahimi-Movaghar
Department of Neurosurgery Faculty Papers
Study Design
Systematic Review and Meta-Analyses.
Objective
To assess the 30- and 90-day readmission rates after a traumatic spinal cord injury (SCI).
Methods
A systematic search of MEDLINE and Embase was performed. The period was from inception to June 2022, with no language restrictions. All studies investigating the 30- and/or 90-day readmission rate following traumatic SCI were included. A random-effects model to combine effect sizes in our meta-analysis was applied.
Results
Seven out of 2959 reports met eligibility. The mean age of the patients was 50.2 ± 19.9, with a male-to-female ratio of 2.4:1. The most common traumatic SCI was …
Educating Staff To Use The Teach-Back Method Towards Improving Adherence To Antipsychotic Medication, Elizabeth Adebayo
Educating Staff To Use The Teach-Back Method Towards Improving Adherence To Antipsychotic Medication, Elizabeth Adebayo
Walden Dissertations and Doctoral Studies
My goal for this staff education doctoral project was to improve adherence to antipsychotic medication among patients in a mental health facility through an education initiative for psychiatric intensive care unit staff focused on the teach-back method. The facility had reported a 20% increase in medication noncompliance among post-discharge patients within the past year, primarily attributed to nurses’ lack of adequate patient teaching strategies. I addressed the issue of effective patient education using the teach-back method in improving medication adherence in an inpatient mental health setting. Teaching objectives, content, and test questions were developed based on a substantial body of …
Clinical Utility Of Opencap Motion Analysis In Lower Limb Prosthesis Users, Sarahi Fernandez Leon
Clinical Utility Of Opencap Motion Analysis In Lower Limb Prosthesis Users, Sarahi Fernandez Leon
Honors Program Theses and Research Projects
The use of prosthetics has gradually increased due to various diseases, and it is estimated that 35-40 million people are prosthetic/orthotic users, with the number estimated to increase to two billion by 2050. Mobility has been determined to be a strong predictor of quality of life. There are various ways to measure mobility and predict outcomes in lower-limb amputees (LLA), such as self-report and performance-based measures. However, these come with many limitations, showcasing the need for quantitative measures of gait parameters to allow for better development of prosthetic components. Motion analysis tools are expensive and time consuming, but an inexpensive, …
Functional Connectivity Biomarker Extraction For Schizophrenia Based On Energy Landscape Machine Learning Techniques, Janerra D Allen, Sravani Varanasi, Fei Han, L Elliot Hong, Fow-Sen Choa
Functional Connectivity Biomarker Extraction For Schizophrenia Based On Energy Landscape Machine Learning Techniques, Janerra D Allen, Sravani Varanasi, Fei Han, L Elliot Hong, Fow-Sen Choa
Faculty, Staff and Student Publications
Brain connectivity represents the functional organization of the brain, which is an important indicator for evaluating neuropsychiatric disorders and treatment effects. Schizophrenia is associated with impaired functional connectivity but characterizing the complex abnormality patterns has been challenging. In this work, we used resting-state functional magnetic resonance imaging (fMRI) data to measure functional connectivity between 55 schizophrenia patients and 63 healthy controls across 246 regions of interest (ROIs) and extracted the disease-related connectivity patterns using energy landscape (EL) analysis. EL analysis captures the complexity of brain function in schizophrenia by focusing on functional brain state stability and region-specific dynamics. Age, sex, …
Trajectory, Interactions, And Predictors Of Higher Symptom Burden During Induction Therapy For Multiple Myeloma, Mona Kamal, Qiuling Shi, Shu-En Shen, Charles Cleeland, Xin Shelley Wang
Trajectory, Interactions, And Predictors Of Higher Symptom Burden During Induction Therapy For Multiple Myeloma, Mona Kamal, Qiuling Shi, Shu-En Shen, Charles Cleeland, Xin Shelley Wang
Faculty, Staff and Student Publications
Background: Patients with multiple myeloma (MM) experience disabling symptoms that are difficult to manage and may persist after induction therapy. Monitoring disease-related and induction therapy-induced symptoms and identifying patients at greater risk for high symptom burden are unmet clinical needs. The objective of this study was to examine the trajectories of symptom severity over time and identify predictors of high symptom burden during MM induction therapy.
Methodology: Eligible patients with MM rated their symptoms by completing the MD Anderson Symptom Inventory MM module repeatedly during 16 weeks of induction therapy. Group-based trajectory modeling identified patient groups with persistently high-severity (versus …
A Retrospective Validation Of The Hear Score., Jordan Luli, Andrew Scheidemantel, Katelyn Bennett, Jessalyn Schafer, Andrew Costa, Marie Lockhart, Kevin Stiver
A Retrospective Validation Of The Hear Score., Jordan Luli, Andrew Scheidemantel, Katelyn Bennett, Jessalyn Schafer, Andrew Costa, Marie Lockhart, Kevin Stiver
Heart and Vascular Articles
Studies have proposed the history, electrocardiogram, age, risk factors (HEAR) score to risk-stratify patients with chest pain in the emergency department. This paper assessed the utility of the HEAR score for ambulatory patients with chest pain. The findings demonstrate patients with low and high HEAR scores can be safely managed in the outpatient setting.
Diet And Immune Effects Trial (Diet)- A Randomized, Double-Blinded Dietary Intervention Study In Patients With Melanoma Receiving Immunotherapy, Rachel M Farias, Yan Jiang, Erma J Levy, Cindy Hwang, Jian Wang, Elizabeth M Burton, Lorenzo Cohen, Nadim Ajami, Jennifer A Wargo, Carrie R Daniel, Jennifer L Mcquade
Diet And Immune Effects Trial (Diet)- A Randomized, Double-Blinded Dietary Intervention Study In Patients With Melanoma Receiving Immunotherapy, Rachel M Farias, Yan Jiang, Erma J Levy, Cindy Hwang, Jian Wang, Elizabeth M Burton, Lorenzo Cohen, Nadim Ajami, Jennifer A Wargo, Carrie R Daniel, Jennifer L Mcquade
Faculty, Staff and Student Publications
Background: Gut microbiome modulation is a promising strategy for enhancing the response to immune checkpoint blockade (ICB). Fecal microbiota transplant studies have shown positive signals of improved outcomes in both ICB-naïve and refractory melanoma patients; however, this strategy is challenging to scale. Diet is a key determinant of the gut microbiota, and we have previously shown that (a) habitual high dietary fiber intake is associated with an improved response to ICB and (b) fiber manipulation in mice impacts antitumor immunity. We recently demonstrated the feasibility of a controlled high-fiber dietary intervention (HFDI) conducted in melanoma survivors with excellent compliance and …
Alzheimer's Disease-Linked Risk Alleles Elevate Microglial Cgas-Associated Senescence And Neurodegeneration In A Tauopathy Model, Gillian K Carling, Xiaoying Chen, David M Holtzman, Et Al.
Alzheimer's Disease-Linked Risk Alleles Elevate Microglial Cgas-Associated Senescence And Neurodegeneration In A Tauopathy Model, Gillian K Carling, Xiaoying Chen, David M Holtzman, Et Al.
2020-Current year OA Pubs
The strongest risk factors for late-onset sporadic Alzheimer's disease (AD) include the ε4 allele of apolipoprotein E (APOE), the R47H variant of triggering receptor expressed on myeloid cells 2 (TREM2), and female sex. Here, we combine APOE4 and TREM2