Medicine and Health Sciences Commons^™

Exploring Hypertension Prevalence Through Perceived Health Beliefs, Sarah E. Wagman

Honors Capstones

Hypertension is a form of heart disease that is extremely prevalent, affecting many Americans. This disease manifests from countless risk factors often modifiable from an individual’s lifestyle behavior. Many health initiatives are understood by the public including healthy eating, exercise, and maintaining adequate health, but incidence continues to rise. To better understand this occurrence, a framework called the Health Belief Model is used to answer why individuals make the health decisions that they do in relation to hypertension. Participants in both individual, small group, and large group settings were invited to attend a Hypertension Awareness Event. Participants were asked to …

Bile Duct Ligation-Induced Cirrhosis Does Not Alter The Blood-Brain Barrier Permeability To Sucrose In Rats, Mohammad K. Miah, Ulrich Bickel, Reza Mehvar

Pharmacy Faculty Articles and Research

Contradictory results have been reported about the effects of liver diseases on the blood-brain barrier (BBB) permeability to markers. For instance, both an increase and no change in the BBB permeability to BBB markers sodium fluorescein and Evans blue have been reported in experimental cholestasis induced by bile duct ligation (BDL) in rats. These contradictory effects might be due to inherent limitations of these markers and/or methodological issues. Here, we investigated the time course of the impact of BDL in rats on BBB permeability using a recently developed stable isotope labeled marker [¹³C]sucrose, which is expected to be …

Medical School Watercooler Newsletter - December 5, 2024, Lindsay Hughes

Watercooler Newsletter

This is the Thursday, December 5, 2024 edition of the Frederick P. Whiddon College of Medicine's newsletter -- Watercooler.

Contents include:

• Students, faculty present research at international meeting on tropical medicine
• Medical students present research on peer-to-peer learning at national conference
• USA Health Pediatrics expands with addition of Weidow
• Pierce elected chair of APQI Steering Committee
• Creg named director of Office of Continuing Medical Education
• Dasgupta receives 2024 Mayer Mitchell Award for Excellence in Cancer Research
• Pathology resident presents research on melanoma at national dermapathology conference
• USA Health welcomes Benjamin to infectious disease division

Computational Logp Calculations And Determination Of Lipophilicity Values Of Fluorinated Morphine Derivatives, Mirabella Romano, Allison Vu, Emily Chen

Student Scholar Symposium Abstracts and Posters

The addictive effect of opioids impacted 60 million people globally in 2023. This opioid crisis necessitates the development of opioid derivatives that maintain analgesic efficacy while minimizing addictive effects from opioid use. The present work focuses on morphine, a commonly prescribed opioid with high affinity to the mu-opioid receptor (MOR). Morphine binds non-selectively within both healthy and inflamed tissue. By modifying morphine’s structure through fluorination to counteract its non-selective binding, the drug’s pharmacological ability to provide effective pain relief comes with a lower risk of addiction. Specifically, the addition of fluorine to differing beta positions of the main binding site …

Randomized Clinical Trial To Compare Cryopreserved And Lyopreserved Umbilical Cord Tissue To Treat Complex Diabetic Foot Wounds, Lawrence A. Lavery, Mehmet A. Suludere, Matthew J. Johnson, Amanda Killeen, Katherine M. Raspovic, Peter A. Crisologo, Arthur Tarricone

School of Podiatric Medicine Publications

To compare the incidence of infection, wound closure and time to wound closure in patients treated with cryopreserved (CPUT) and lyopreserved umbilical tissue (LPUT) in complex diabetic surgical wounds. This single-blinded 12-week randomized clinical trial compared cryopreserved and lyopreserved amniotic cord tissue to treat complex diabetic foot wounds. LPUT or CRAT was applied at baseline and again after four weeks. We enrolled subjects with UT2A-D and 3A-D wounds (depth to tendon, muscle, or bone with infection and/or PAD) and excluded subjects with ABI < 0.5 or TBI < 0.3, untreated osteomyelitis, and autoimmune diseases. We used a 3-D camera to evaluate wound area and volume. The mean baseline wound areas were 12.9 ± 10.7 cm2 for CPUT and 11.7 ± 7.0 cm2 for LPUT. The mean baseline wound volume was 7.5 ± 8.1 for CPUT and 9.2 ± 10.2 cm3 for LPUT. There was no difference between CPUT and LPUT in wound closure (36.8% vs 19.0%, P = .21) or infection (10.5% vs 4.8%, P = .60). There was no difference in mean …

Health Services Monthly Educational Newsletter To Parents/Guardians, Dena L. Hinkle, Jennifer L. Fisher, Emily Garnett, Chelsea K. Mckee

Nursing Department Graduate Presentations/Conferences

This health services newsletter was created as an educational and information tool for parents/guardians of Will County School District 92. The intention of this project was to increase student compliance with health requirements, improve parental/guardian education regarding student health, and provide necessary student health education topics. The project began by completing a literature review which allowed for a thorough survey of existing information. The theoretical framework Whole School, Whole Community, Whole Child (WSCC) serves as the foundation for this proposal, along with Pender’s Health Promotion Model and the School Nursing Practice Framework. The three graduate nursing students determined important educational …

Health Education Curriculum Effectiveness And The Role Of The School Nurse, Dena L. Hinkle, Jennifer L. Kilgos-Conwell, Dipika C. Patel, Christina R. Segal

Nursing Department Graduate Presentations/Conferences

Background: The National Association of School Nurses (NASN) identifies the teaching of health promotion, health literacy, and disease prevention as one of the practice principles of school nurses (NASN, 2024). The aim of this project was to examine how health education topics and curriculum in school districts is determined, who is teaching the curriculum, and if there is a role for the school nurse in the development, collaboration or teaching of the curriculum.

Purpose: The project investigated if school nurses are involved in the selection and/or teaching of the curriculum chosen by the district. Input from school nurses and physical …

Predictors Of Longitudinal Symptom Trajectory In Young Adults With Low Back Pain, Abby Borlovan, Julia Leigh, Jo Armour Smith

Student Scholar Symposium Abstracts and Posters

Predictors of longitudinal symptom trajectory in young adults with low back pain. Severity and frequency of painful episodes change over time in individuals with chronic low back pain (LBP). Recalling previous episodes’ severity/frequency is often considered inaccurate. This study’s purpose was to determine if recall of LBP history or psychological characteristics are predictors of future symptom trajectories in young adults with LBP. The 57 young adult participants had a year or more history of LBP and were not currently in pain. At baseline, LBP history was characterized by recall of pain severity and frequency during symptomatic episodes. Participants completed measures …

Effects Of Simultaneous Smartphone Texting And Auditory Stimulation On Gait, Sebastian Herrera Vargas

Student Scholar Symposium Abstracts and Posters

More often than not, pedestrians around busy college campuses, business parks, and shopping malls are seen walking while using their phones and listening to music or having earphones in. Activities on pedestrians’ phones that captivate them more and require higher cognitive processing demonstrated a higher detriment to their gait kinematics than less cognitively complicated activities (Brennan and Preloff, 2021). This study aims to establish whether or not gait parameters are affected by walking while engaging in cognitively demanding activities such as texting and listening to green noise. Green noise is a deviation from white noise, which amplifies the mid-range frequencies …

Ai-Enabled Wearable Cameras For Assisting Dietary Assessment In African Populations, Frank P-W Lo, Jianing Qiu, Modou L Jobarteh, Yingnan Sun, Zeyu Wang, Shuo Jiang, Tom Baranowski, Alex K Anderson, Megan A Mccrory, Edward Sazonov, Wenyan Jia, Mingui Sun, Matilda Steiner-Asiedu, Gary Frost, Benny Lo

Children’s Nutrition Research Center Staff Publications

We have developed a population-level method for dietary assessment using low-cost wearable cameras. Our approach, EgoDiet, employs an egocentric vision-based pipeline to learn portion sizes, addressing the shortcomings of traditional self-reported dietary methods. To evaluate the functionality of this method, field studies were conducted in London (Study A) and Ghana (Study B) among populations of Ghanaian and Kenyan origin. In Study A, EgoDiet's estimations were contrasted with dietitians' assessments, revealing a performance with a Mean Absolute Percentage Error (MAPE) of 31.9% for portion size estimation, compared to 40.1% for estimates made by dietitians. We further evaluated our approach in Study …

Composting For Cleaner Air, Simi Benisty, Katie Bui, Narmin Solman, David Woo

Master's Projects and Capstones

The aim of this project was to address food waste at Mary's Kitchen by implementing a composting initiative to divert organic waste from landfills. The project took place in a nonprofit organization that serves food to the homeless, where the target population includes staff, volunteers, and clients of the kitchen. Key interventions involved creating educational materials on composting, recycling, and waste management, including flyers in both English and Spanish, as well as a QR code for easy access. Additionally, smaller, color-coded buckets were introduced to replace the 33-gallon bins, making waste sorting more manageable. Measures included staff and volunteer compliance …

Liar-Dependent Gene Expression Contributes To Antimicrobial Responses In Group A, Luis Alberto Vega, Misú Sanson-Iglesias, Piyali Mukherjee, Kyle D Buchan, Gretchen Morrison, Anne E Hohlt, Anthony R Flores

Faculty, Staff and Student Publications

The ability to sense and respond to host defenses is essential for pathogen survival. Some mechanisms involve two-component systems (TCSs) that respond to host molecules, such as antimicrobial peptides (AMPs), and activate specific gene regulatory pathways to aid in survival. Alongside TCSs, bacteria coordinate cell division proteins, chaperones, cell wall sortases, and secretory translocons at discrete locations within the cytoplasmic membrane, referred to as functional membrane microdomains (FMMs). In group A Streptococcus (GAS), the FMM or “ExPortal” coordinates protein secretion, cell wall synthesis, and sensing of AMP-mediated cell envelope stress via the LiaFSR three-component system. Previously, we showed that GAS …

Clonal Landscape And Clinical Outcomes Of Telomere Biology Disorders: Somatic Rescue And Cancer Mutations, Fernanda Gutierrez-Rodrigues, Emma M Groarke, Natthakan Thongon, Juan Jose Rodriguez-Sevilla, Luiz Fernando B Catto, Marena R Niewisch, Ruba Shalhoub, Lisa J Mcreynolds, Diego V Clé, Bhavisha A Patel, Xiaoyang Ma, Dalton Hironaka, Flávia S Donaires, Nina Spitofsky, Barbara A Santana, Tsung-Po Lai, Lemlem Alemu, Sachiko Kajigaya, Ivana Darden, Weiyin Zhou, Paul V Browne, Subrata Paul, Justin Lack, David J Young, Courtney D Dinardo, Abraham Aviv, Feiyang Ma, Michel Michels De Oliveira, Ana Paula De Azambuja, Cynthia E Dunbar, Malgorzata Olszewska, Emmanuel Olivier, Eirini P Papapetrou, Neelam Giri, Blanche P Alter, Carmem Bonfim, Colin O Wu, Guillermo Garcia-Manero, Sharon A Savage, Neal S Young, Simona Colla, Rodrigo T Calado

Faculty, Staff and Student Publications

Telomere biology disorders (TBDs), caused by pathogenic germ line variants in telomere-related genes, present with multiorgan disease and a predisposition to cancer. Clonal hematopoiesis (CH) as a marker of cancer development and survival in TBDs is poorly understood. Here, we characterized the clonal landscape of a large cohort of 207 patients with TBD with a broad range of age and phenotype. CH occurred predominantly in symptomatic patients and in signature genes typically associated with cancers: PPM1D, POT1, TERT promoter (TERTp), U2AF1S34, and/or TP53. Chromosome 1q gain (Chr1q+) was the commonest karyotypic abnormality. Clinically, multiorgan involvement and CH in TERTp, TP53, …

A Heuristic Evaluation Of A Pharmacy Surveillance Information System, Reza Abbasi, Mehrdad Farzandipour, Habiballah Rahimi, Yang Gong, Ehsan Nabovati

Faculty, Staff and Student Publications

Introduction: The pharmacy surveillance information system (PSIS) is intended to manage the dispensing practice of under-controlled drugs and substances. We designed and developed a PSIS for the first time in a developing country. This study aimed to evaluate the usability of this system using a heuristic evaluation method before the pilot implementation in outpatient pharmacies.

Materials and methods: The study was conducted in 2022 during the development of a pharmacy surveillance information system. Five evaluators examined the system using Nielson's heuristic evaluation method. The detected usability problems were categorized into 10 Nielson's usability principles, and their severity was calculated.

Results: …

Integrative Multi-Omics Analysis Uncovers Tumor-Immune-Gut Axis Influencing Immunotherapy Outcomes In Ovarian Cancer, Spencer R Rosario, Mark D Long, Shanmuga Chilakapati, Eduardo Cortes Gomez, Sebastiano Battaglia, Prashant K Singh, Jianmin Wang, Katy Wang, Kristopher Attwood, Suzanne M Hess, A J Robert Mcgray, Kunle Odunsi, Brahm H Segal, Gyorgy Paragh, Song Liu, Jennifer A Wargo, Emese Zsiros

Faculty, Staff and Student Publications

Recurrent ovarian cancer patients, especially those resistant to platinum, lack effective curative treatments. To address this, we conducted a phase 2 clinical trial (NCT02853318) combining pembrolizumab with bevacizumab, to increase T cell infiltration into the tumor, and oral cyclophosphamide, to reduce the number of regulatory T cells. The trial accrued 40 heavily pretreated recurrent ovarian cancer patients. The primary endpoint, progression free survival, was extended to a median of 10.2 months. The secondary endpoints demonstrated an objective response rate of 47.5%, and disease control in 30% of patients for over a year while maintaining a good quality of life. We …

Natural Medicine Use In Costa Rica, Elizabeth Krol

Honors Theses

This study explores the role of natural medicine in Costa Rican culture, while focusing on its historical, cultural, and clinical significance. With a literature review, ethnobotanical research, and a study abroad experience, this paper highlights the integration of natural, herbal medicine into modern healthcare. Costa Rica’s rich biodiversity, with its varied microclimates and abundant medicinal plants, forms a strong foundation for traditional herbal medicine. Indigenous groups such as the BriBri and Cabécar contributed significantly to this legacy, which has evolved through interactions with European and Afro-Caribbean populations.

Research emphasizes the cultural importance of herbal medicine within the “Pura Vida” lifestyle, …

Spatial Dynamics Of Culex Quinquefasciatus Abundance: Geostatistical Insights From Harris County, Texas, Morgan Jibowu, Melissa S Nolan, Ryan Ramphul, Heather T Essigmann, Abiodun O Oluyomi, Eric L Brown, Maximea Vigilant, Sarah M Gunter

Faculty, Staff and Students Publications

Mosquito-borne diseases pose a significant public health threat, prompting the need to pinpoint high-risk areas for targeted interventions and environmental control measures. Culex quinquefasciatus is the primary vector for several mosquito-borne pathogens, including West Nile virus. Using spatial analysis and modeling techniques, we investigated the geospatial distribution of Culex quinquefasciatus abundance in the large metropolis of Harris County, Texas, from 2020 to 2022. Our geospatial analysis revealed clusters of high mosquito abundance, predominantly located in central Houston and the north-northwestern regions of Harris County, with lower mosquito abundance observed in the western and southeastern areas. We identified persistent high mosquito …

Rna Splicing As A Biomarker And Phenotypic Driver Of Meningioma Dna-Methylation Groups, Nathan K Leclair, Abrar Choudury, William C Chen, Stephen T Magill, Kathleen Mccortney, Craig M Horbinski, Zhenhong Chen, Ezequiel Goldschmidt, Charlotte D Eaton, Ketan R Bulsara, Wenya Linda Bi, Akash J Patel, Felix Sahm, David Raleigh, Olga Anczukow

Faculty, Staff and Students Publications

BACKGROUND: Advances in our understanding of the molecular biology of meningiomas have led to significant gains in the ability to predict patient prognosis and tumor recurrence and to identify novel targets for therapeutic design. Specifically, classification of meningiomas based on DNA methylation has greatly improved our ability to risk stratify patients, however new questions have arisen in terms of the underlying impact these DNA-methylation signatures have on meningioma biology.

METHODS: This study utilizes RNA-sequencing data from 486 meningioma samples corresponding to 3 meningioma DNA-methylation groups (merlin-intact, immune-enriched, and hypermitotic), followed by in vitro experiments utilizing human meningioma cell lines.

RESULTS: …

Immune Landscape Of Isocitrate Dehydrogenase-Stratified Primary And Recurrent Human Gliomas, Pravesh Gupta, Minghao Dang, Shivangi Oberai, Simona Migliozzi, Rakesh Trivedi, Gayatri Kumar, Mekenzie Peshoff, Nancy Milam, Aml Ahmed, Krishna Bojja, Tuan M Tran, Joy Gumin, Carlos Kamiya-Matsuoka, Jason Huse, Kathryn Cox, Jianzhuo Li, Huma Shehwana, Sameer A Sheth, Rodriguez Saxon, Sun Baohua, Brittany Parker Kerrigan, Atul Maheshwari, Edwin Roger Parra Cuentas, Nicholas E Navin, Amy B Heimberger, Frederick F Lang, Antonio Iavarone, Karen Clise-Dwyer, Linghua Wang, Krishna P Bhat

Faculty, Staff and Student Publications

Background: Human gliomas are classified using isocitrate dehydrogenase (IDH) status as a prognosticator; however, the influence of genetic differences and treatment effects on ensuing immunity remains unclear.

Methods: In this study, we used sequential single-cell transcriptomics on 144 678 and spectral cytometry on over 2 million immune cells encompassing 48 human gliomas to decipher their immune landscape.

Results: We identified 22 distinct immune cell types that contribute to glioma immunity. Specifically, brain-resident microglia (MG) were reduced with a concomitant increase in CD8+ T lymphocytes during glioma recurrence independent of IDH status. In contrast, IDH-wild type-associated patterns, such as an abundance …

Amniotic Fluid-Derived Stem Cells: Potential Factories Of Natural And Mimetic Strategies For Congenital Malformations, Cristiane S R Fonteles, Julia Enterria-Rosales, Ying Lin, John W Steele, Ramiro A Villarreal-Leal, Jing Xiao, Daniel I Idowu, Beck Burgelin, Bogdan J Wlodarczyk, Richard H Finnell, Bruna Corradetti

Faculty, Staff and Students Publications

BACKGROUND: Mesenchymal stem cells (MSCs) derived from gestational tissues offer a promising avenue for prenatal intervention in congenital malformations although their application is hampered by concerns related to cellular plasticity and the need for invasive, high-risk surgical procedures. Here, we present naturally occurring exosomes (EXOs) isolated from amniotic fluid-derived MSCs (AF-MSCs) and their mimetic analogs (MIMs) as viable, reproducible, and stable alternatives. These nanovesicles present a minimally invasive therapeutic option, addressing the limitations of MSC-based treatments while retaining therapeutic efficacy.

METHODS: MIMs were generated from AF-MSCs by combining sequential filtration steps through filter membranes with different porosity and size exclusion …

Exploration Of The Tunability Of Brd4 Degradation By Dcaf16 Trans-Labelling Covalent Glues, Muhammad Murtaza Hassan, Yen-Der Li, Michelle W Ma, Mingxing Teng, Woong Sub Byun, Kedar Puvar, Ryan Lumpkin, Brittany Sandoval, Justine C Rutter, Cyrus Y Jin, Michelle Y Wang, Shawn Xu, Anna M Schmoker, Hakyung Cheong, Brian J Groendyke, Jun Qi, Eric S Fischer, Benjamin L Ebert, Nathanael S Gray

Faculty, Staff and Students Publications

Chemically induced proximity modalities such as targeted protein degradation (TPD) hold promise for expanding the number of proteins that can be manipulated pharmacologically. However, current TPD strategies are often limited to proteins with preexisting ligands. Molecular glues (e.g. glutarimide ligands for CUL4CRBN), offer the potential to target undruggable proteins. Yet, their rational design is largely unattainable due to the unpredictability of the ‘gain-of-function’ nature of the glue interaction upon chemical modification of ligands. We recently reported a covalent trans-labelling glue mechanism which we named ‘Template-assisted covalent modification’, where an electrophile decorated BRD4 inhibitor was effectively delivered to …

Integrating Drug Target Information In Deep Learning Models To Predict The Risk Of Adverse Events In Patients With Comorbid Post-Traumatic Stress Disorder And Alcohol Use Disorder, Oshin Miranda, Xiguang Qi, M Daniel Brannock, Ryan Whitworth, Thomas R Kosten, Neal David Ryan, Gretchen L Haas, Levent Kirisci, Lirong Wang

Faculty, Staff and Students Publications

Background/Objectives: Comorbid post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) patients are at a significantly higher risk of adverse outcomes, including opioid use disorder, depression, suicidal behaviors, and death, yet limited treatment options exist for this population. This study aimed to build on previous research by incorporating drug target information into a novel deep learning model, T-DeepBiomarker, to predict adverse outcomes and identify potential therapeutic medications.

Methods: We utilized electronic medical record (EMR) data from the University of Pittsburgh Medical Center (UPMC), analyzing 5565 PTSD + AUD patients. T-DeepBiomarker was developed by integrating multimodal data, including lab results, drug …

3d Genome Topology Distinguishes Molecular Subgroups Of Medulloblastoma, John J Y Lee, Michael J Johnston, Hamza Farooq, Huey-Miin Chen, Subhi Talal Younes, Raul Suarez, Melissa Zwaig, Nikoleta Juretic, William A Weiss, Jiannis Ragoussis, Nada Jabado, Michael D Taylor, Marco Gallo

Faculty, Staff and Students Publications

Four main medulloblastoma (MB) molecular subtypes have been identified based on transcriptional, DNA methylation, and genetic profiles. However, it is currently not known whether 3D genome architecture differs between MB subtypes. To address this question, we performed in situ Hi-C to reconstruct the 3D genome architecture of MB subtypes. In total, we generated Hi-C and matching transcriptome data for 28 surgical specimens and Hi-C data for one patient-derived xenograft. The average resolution of the Hi-C maps was 6,833 bp. Using these data, we found that insulation scores of topologically associating domains (TADs) were effective at distinguishing MB molecular subgroups. TAD …

Targeting The Cholesterol Storage Enzyme Acat1/Soat1 In Brain Cells And Mouse Model: A Novel Approach To Address Aging And Apoe4-Related Neuroinflammation, Thao Nguyen Phuong Huynh Krumeich

Dartmouth College Ph.D Dissertations

Alzheimer’s Disease (AD) is a progressive neurodegenerative disease that significantly impacts nearly 7 million people in the United States. AD is characterized by the deposition of amyloid beta (Ab) plaque, tau neurofibrillary tangles (NFTs), lipids granules, and neuroinflammation. Age and apolipoprotein E4 (APOE4) are the two biggest risk factors for AD. Recent AD therapeutic development has mostly benefited the patient population with milder symptoms while causing serious side effects in APOE4 carriers, leaving the most impacted patients’ group - aged APOE4 carriers with no treatment option. With the increasing aging population, there is an urgent need for a …

Cellular Trafficking And Fate Mapping Of Cells Within The Nervous System After In Utero Hematopoietic Cell Transplantation, Matthew T Grant, Hemanth Ramesh Nelvagal, Maria Tecos, Amal Hamed, Kerry Swanson, Jonathan D Cooper, Jesse D Vrecenak

2020-Current year OA Pubs

In utero hematopoietic cell transplantation (IUHCT) utilizes fetal immune tolerance to achieve durable chimerism without conditioning or immunosuppression during a unique window in fetal development. Though donor cells have been observed within the nervous system following in utero injection, the timeline and distribution of cellular trafficking across the blood-brain barrier following IUHCT is not well understood. We injected 20 × 10

Remotely Delivered Yoga Therapy For Chronic Pain: A Case Study, Patience Kaltenbach, Laura Edoff, Marlysa Sullivan, Steffany Moonaz

Journal of Applied Yoga Studies

Many people seek yoga as a complementary therapy for the management of chronic pain. Barriers to maintaining care for chronic pain conditions include pain with movement, fear of exacerbating symptoms, limited resources for long-term care plans, and a lack of individualized self-management instruction. In this case study, the yoga therapist implemented an integrative framework to address the needs of a client impacted by fibromyalgia primarily using video-conferencing software. This adaptive approach demonstrates the feasibility and potential benefits of remote yoga therapy for chronic pain, including improved adherence, long-term pain management, and self-efficacy for maintaining quality of life initiated by client-motivated …

Effect Of Yoga Therapy For Managing Migraine: A Case Series, Andrea Moran, Lori Rubenstein Fazzio

Journal of Applied Yoga Studies

Migraine is a common disabling primary headache disorder. It is characterized by symptoms lasting 4-72 hours, headache with unilateral location, pulsating quality, moderate or severe intensity, aggravation by routine physical activity, and association with nausea and/or photophobia and phonophobia. In this case series four females in the age range of 25-57 presented complaints of migraine headaches affecting their everyday lives. Additionally, they reported emotional challenges accompanying chronic pain due to migraine headaches such as stress, sleep deprivation, and anxiety. An online eight-week yoga therapy program was given for the management of migraine headaches. This program included lifestyle modifications, postures, breathing …

A Comparative Study Of Yoga And Stoicism For Achieving Mental Well-Being, Dr. R K Roshni Raj Lakshmi, Mr. Puyam Robinchandra Singh

Journal of Applied Yoga Studies

Background: The ideal way of life is a question perused upon by many thinkers. Western philosophy as well as Indian philosophy has dwelled on this. A common thread can be seen running through philosophical schools of stoicism and yoga. Evidence can be seen in both schools of philosophy to prove this similarity. The concepts of stoicism like the dual powers leading to creation, concept of eudemonia, restraint of sense organs and control of desire find their equivalent concepts in yoga texts. It can be thus, concluded that stoicism can be seen intertwined in yoga philosophy.

Aim of the philosophical study: …

A Philosophical And Spiritual Design For Prenatal Yoga Courses, Tia A. Arriola

Journal of Applied Yoga Studies

Fear and anxiety dominate much of the global birth culture, whereby approximately 80% of pregnant women report worrying with regard to the natural risks of childbirth (Rublein & Muschalla, 2022). This leads to increased rates of antenatal stress and postpartum depression. These psychosocial responses present risk factors for adverse developmental and health outcomes for the fetus, newborn, mother, and family (Shakarami et al., 2021). In the Western context, the overwhelming response is to increasingly medicalized childbirth, which, while offering life-saving support, may also pose its own set of adverse risks for mother and infant. Therefore, alterative and complementary approaches that …

Impact Of For-Credit Mindfulness Course On Student Resilience, Engagement, And Mental Health, Linda Yaron Weston

Journal of Applied Yoga Studies

This paper highlights the impact of a university for-credit introductory mindfulness course. Research compiled from student reflections, surveys, and interviews revealed that it had a notable impact on personal growth and development, including the capacity to navigate challenges, manage difficult emotions, and build resilience. This enhanced student learning, decision making, engagement, and connection to themselves, others, and the world around them. Course pedagogy and curriculum are included here alongside a narrative account of student experiences in the course. These findings indicate a promising practice for schools to include well-being supports in the student experience.