Open Access. Powered by Scholars. Published by Universities.®

Medicine and Health Sciences Commons™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 37921 - 37950 of 325752

Full-Text Articles in Medicine and Health Sciences

High Diversity Of Dietary Flavonoid Intake Is Associated With A Lower Risk Of All-Cause Mortality And Major Chronic Diseases, Benjamin H. Parmenter, Alysha S. Thompson, Nicola P. Bondonno, Amy Jennings, Kevin Murray, Aurora Perez-Cornago, Jonathan M. Hodgson, Anna Tresserra-Rimbau, Tilman Kühn, Aedín Cassidy Jan 2025

High Diversity Of Dietary Flavonoid Intake Is Associated With A Lower Risk Of All-Cause Mortality And Major Chronic Diseases, Benjamin H. Parmenter, Alysha S. Thompson, Nicola P. Bondonno, Amy Jennings, Kevin Murray, Aurora Perez-Cornago, Jonathan M. Hodgson, Anna Tresserra-Rimbau, Tilman Kühn, Aedín Cassidy

Research outputs 2022 to 2026

Higher habitual intakes of dietary flavonoids have been linked with a lower risk of all-cause mortality and major chronic disease. Yet, the contribution of diversity of flavonoid intake to health outcomes remains to be investigated. Here, using a cohort of 124,805 UK Biobank participants, we show that participants who consumed the widest diversity of dietary flavonoids, flavonoid-rich foods and/or specific flavonoid subclasses had a 6–20% significantly lower risk of all-cause mortality and incidence of cardiovascular disease, type 2 diabetes, cancer, respiratory disease and neurodegenerative disease. Furthermore, we report that both quantity and diversity of flavonoids are independent predictors of mortality …

Go to article

Increased Nitrate Intake From Beetroot Juice Over 4 Weeks Changes The Composition Of The Oral, But Not The Intestinal Microbiome, Rebeka Fejes, Joana Séneca, Petra Pjevac, Martin Lutnik, Stefan Weisshaar, Nina Pilat, Romy Steiner, Karl Heinz Wagner, Richard J. Woodman, Catherine P. Bondonno, Jonathan M. Hodgson, David Berry, Michael Wolzt, Oliver Neubauer Jan 2025

Increased Nitrate Intake From Beetroot Juice Over 4 Weeks Changes The Composition Of The Oral, But Not The Intestinal Microbiome, Rebeka Fejes, Joana Séneca, Petra Pjevac, Martin Lutnik, Stefan Weisshaar, Nina Pilat, Romy Steiner, Karl Heinz Wagner, Richard J. Woodman, Catherine P. Bondonno, Jonathan M. Hodgson, David Berry, Michael Wolzt, Oliver Neubauer

Research outputs 2022 to 2026

Inorganic dietary nitrate, metabolized through an endogenous pathway involving nitrate reducing bacteria, improves cardiovascular health, but its effects on the oral and intestinal microbiomes of older adults with treated hypertension are unknown. Our study investigated the effects of nitrate from beetroot juice on the oral and intestinal microbiomes of this population. A randomized, double-blind, placebo-controlled crossover trial was conducted with 15 participants (age range: 56–71 years), who consumed nitrate-rich or nitrate-depleted (placebo) beetroot juice for 4 weeks. The oral microbiome analysis revealed an increase in Neisseria and a decrease in Veillonella relative abundance (for both, PERMANOVA p < 0.001), with no significant changes in the intestinal microbiome composition. Our findings suggest that an increased dietary nitrate intake from a vegetable source may selectively modulate the oral microbiome and promote an increased abundance of nitrate-reducing species, which was previously associated with improved cardiovascular health outcomes.

Go to article

Moderate-To-Late Preterm Infants Benefit From The Early Collaborative Intervention: Primary Outcomes Of An Rct, Ulrika Birberg Thornberg, Felix Sebastian Koch, Charlotte Sahlén Helmer, Jonna Tell, Ellinore Nyberg, Thomas Abrahamsson, Evalotte Mörelius Jan 2025

Moderate-To-Late Preterm Infants Benefit From The Early Collaborative Intervention: Primary Outcomes Of An Rct, Ulrika Birberg Thornberg, Felix Sebastian Koch, Charlotte Sahlén Helmer, Jonna Tell, Ellinore Nyberg, Thomas Abrahamsson, Evalotte Mörelius

Research outputs 2022 to 2026

Aim: This study aimed to determine the longitudinal impact of the EArly Collaborative Intervention (EACI), a three-session early intervention designed to enhance parent-infant interaction, on the developmental outcomes of preterm infants born between 30 + 0 and 35 + 6 weeks of gestation. Methods: This randomised controlled blinded study recruited families in two neonatal intensive care units in Sweden. In this one-year follow-up, 87 infants (standard care = 37, standard care with EACI = 50) were included in the intention-to-treat analysis. The primary study outcomes were cognition, receptive and expressive communication, and fine and gross motor development measured with the …

Go to article

The Impact Of Opening A Private Hospital Emergency Department On The Hospital And Patient Characteristics, Christiana Mustac, John Maxwell, Paola Chivers, Gordon Laing, Terry Bayliss Jan 2025

The Impact Of Opening A Private Hospital Emergency Department On The Hospital And Patient Characteristics, Christiana Mustac, John Maxwell, Paola Chivers, Gordon Laing, Terry Bayliss

Research outputs 2022 to 2026

Introduction Australian public hospital emergency departments (EDs) are under increasing pressure with higher patient volumes, failure to meet triage target times and increased ambulance wait times. Further, there is limited literature exploring how the opening of an ED affects Australian hospitals. This study focuses on Hollywood Private Hospital (HPH), a large private hospital in Western Australian which opened their ED in November 2021. The research aimed to examine how the introduction of the ED influenced the hospital’s service demands and resourcing. Method This study investigated hospital inpatient characteristics including admissions, clinical deterioration episodes, deaths, aft er-hours theatre activity and companion …

Go to article

Cobotic Ultrasound Systems In Obstetric Assessment: A Scoping Review, Caterina Watson, Leisa Armstrong, David Cook, T. M.Shahriar Sazzad, Nayana Parange Jan 2025

Cobotic Ultrasound Systems In Obstetric Assessment: A Scoping Review, Caterina Watson, Leisa Armstrong, David Cook, T. M.Shahriar Sazzad, Nayana Parange

Research outputs 2022 to 2026

Surgical subspecialties have successfully combined robotic technology with traditional practices. In doing so, they have benefited from increased precision in techniques, reduced incidence of surgical complications, and reduced MSK disorders. This scoping review aims to examine the extent of cobotics in obstetric ultrasound. The review was conducted using the JBI PRISMA protocol to map the topic of robotics in obstetric ultrasound. Teleoperated remote ultrasound formed the largest combined clinical cohort of 67 patients. Limitations of the 20-week scan concerned incomplete visualization of fetal structures. These included cavum septi pellucidi, cardiac outflow tracts, kidneys, lips and spine. Third trimester scans omitted …

Go to article

Exercise And Inflammation In Female Survivors Of Breast Cancer: Systematic Review And Meta-Analysis With Secondary Mediation Analysis On Body Composition, Francesco Bettariga, Dennis R. Taaffe, Anita Borsati, Alice Avancini, Sara Pilotto, Stefano G. Lazzarini, Pedro Lopez, Luca Maestroni, Umberto Crainich, Enrico Bandini, John P. Campbell, Timothy D. Clay, Daniel A. Galvão, Robert U. Newton Jan 2025

Exercise And Inflammation In Female Survivors Of Breast Cancer: Systematic Review And Meta-Analysis With Secondary Mediation Analysis On Body Composition, Francesco Bettariga, Dennis R. Taaffe, Anita Borsati, Alice Avancini, Sara Pilotto, Stefano G. Lazzarini, Pedro Lopez, Luca Maestroni, Umberto Crainich, Enrico Bandini, John P. Campbell, Timothy D. Clay, Daniel A. Galvão, Robert U. Newton

Research outputs 2022 to 2026

Purpose: Inflammation plays a key role in breast cancer recurrence and mortality by promoting tumor progression. Exercise significantly reduces pro-inflammatory markers such as IL-6, TNF-α, and CRP, potentially reducing mortality risk. However, it is yet to be determined whether exercise-induced changes in body composition can modulate inflammatory biomarker responses in the breast cancer setting. Methods: We conducted a secondary mediation analysis based on the findings from our previously published systematic review with meta-analysis. Randomized controlled trials examining the effects of exercise on IL-1β, IL-6, IL-8, IL-10, TNF-α, and CRP and body composition and anthropometry measures such as lean mass (LM), …

Go to article

Improving Diet Quality Of People Living With Obesity By Building Effective Dietetic Service Delivery Using Technology In A Primary Health Care Setting: Protocol For A Randomized Controlled Trial, Deborah A. Kerr, Clare E. Collins, Andrea Begley, Barbara Mullan, Satvinder S. Dhaliwal, Claire E. Pulker, Fengqing Zhu, Marie Fialkowski, Richard L. Prince, Richard Norman, Anthony P. James, Paul Aveyard, Helen Mitchell, Jacquie Garton-Smith, Megan E. Rollo, Chloe Maxwell-Smith, Amira Hassan, Hayley Breare, Lucy M. Butcher, Christina M. Pollard Jan 2025

Improving Diet Quality Of People Living With Obesity By Building Effective Dietetic Service Delivery Using Technology In A Primary Health Care Setting: Protocol For A Randomized Controlled Trial, Deborah A. Kerr, Clare E. Collins, Andrea Begley, Barbara Mullan, Satvinder S. Dhaliwal, Claire E. Pulker, Fengqing Zhu, Marie Fialkowski, Richard L. Prince, Richard Norman, Anthony P. James, Paul Aveyard, Helen Mitchell, Jacquie Garton-Smith, Megan E. Rollo, Chloe Maxwell-Smith, Amira Hassan, Hayley Breare, Lucy M. Butcher, Christina M. Pollard

Research outputs 2022 to 2026

Background: Almost a third of Australian adults are living with obesity, yet most cannot access medical nutrition therapy from dietitians, that is, the health professionals trained in dietary weight management services. Across the health system, primary care doctors readily identify people who may benefit from weight management services, but there are limited referral options in the community. Dietitians are trained to provide evidence-informed dietary treatment of overweight and obesity but are underutilized and underresourced. The chat2 (Connecting Health and Technology 2) trial will test combining new technologies for dietary assessment with behavior change techniques to improve outcomes for people living …

Go to article

Mental Health Support Workers Perspectives On Barriers To And Facilitators Of The Effective Delivery Of Their Roles: A Systematic Review And Meta-Aggregation, Martha Njuguna, Irene Ngune, Yvonne Middlewick Jan 2025

Mental Health Support Workers Perspectives On Barriers To And Facilitators Of The Effective Delivery Of Their Roles: A Systematic Review And Meta-Aggregation, Martha Njuguna, Irene Ngune, Yvonne Middlewick

Research outputs 2022 to 2026

Mental health support workers (MHSWs) are an important workforce within the mental health care system. Research shows that support services delivered by MHSWs are effective at improving the outcomes of individuals with mental illness. However, there is also literature suggesting that this group of workers are facing many challenges in their roles. This qualitative systematic review sought to explore, analyze and synthesize available primary research literature on the experiences of MHSWs with the aim of identifying the barriers to and facilitators of effective delivery of their roles. An electronic search of Medline, CINAHL, PsycINFO, and Web of Science was conducted …

Go to article

Normative Data And Objective Benchmarks For Selected Force Plate Tests For Professional And Youth Soccer Players In The English Football League, Andrew J. Badby, Paul Comfort, Nicholas J. Ripley, Peter D. Mundy, Marcos A. Soriano, Francisco J. Robles-Palazón, Jack Fahey, Paul Sindall, Bramah, John J. Mcmahon Jan 2025

Normative Data And Objective Benchmarks For Selected Force Plate Tests For Professional And Youth Soccer Players In The English Football League, Andrew J. Badby, Paul Comfort, Nicholas J. Ripley, Peter D. Mundy, Marcos A. Soriano, Francisco J. Robles-Palazón, Jack Fahey, Paul Sindall, Bramah, John J. Mcmahon

Research outputs 2022 to 2026

The aim of this study was to establish objective benchmarks for countermovement jump (CMJ), countermovement rebound jump (CMRJ), and isometric mid-thigh pull (IMTP) metrics in male professional and youth soccer players. Professional (N = 139; age: 24 ± 5 years; height: 184 ± 7 cm; mass: 81 ± 9 kg) and youth (N = 137; age: 17 ± 1 years; height: 178 ± 17 cm; mass: 72 ± 8 kg) soccer players were recruited from 7 separate clubs. Many CMJ (25/32), CMRJ (24/30), and (2/2) IMTP metrics discriminated between age groups. Significant (p < 0.05) differences were identified in CMJ outcome (4/4), propulsive kinetic (6/6), and relative propulsive kinetic (4/4) metrics, but trivial non-significant (p > 0.05) differences were identified in strategy (4/4) …

Go to article

How Strong Is Strong Enough? Assessing When Physical Performance Tests Cease To Be Predictive Of Sprint Performance In Trained Football Players, Shayne Vial, Mark Scanlan, Philipp Beranek, Daniel Kadlec, Oliver R. Barley, Jodie Cochrane Wilkie Jan 2025

How Strong Is Strong Enough? Assessing When Physical Performance Tests Cease To Be Predictive Of Sprint Performance In Trained Football Players, Shayne Vial, Mark Scanlan, Philipp Beranek, Daniel Kadlec, Oliver R. Barley, Jodie Cochrane Wilkie

Research outputs 2022 to 2026

Vial, S, Scanlan, M, Beranek, P, Kadlec, D, Barley, OR, and Cochrane Wilkie, J. How strong is strong enough? Assessing when physical performance tests cease to be predictive of sprint performance in trained football players. J Strength Cond Res XX(X): 000-000, 2025 - Quantifying underlying capacities of sprint performance are useful for monitoring training and guiding interventions. Traditional statistical techniques, such as correlation and regression analyses, have been widely used to model relationships between physical capacity and sprint performance. However, these methods often assume linearity, potentially oversimplifying complex, nonlinear interactions, and generalizing group-level data that may misrepresent individual trends. For …

Go to article

Concept-Based Curriculum: An Evidence-Based Approach To Developing A New Framework For Dietetics Education?, Andrea Begley, Janica Jamieson, Gemma Jenkins, Janeane Dart, Lauren T. Williams, Simone Gibson, Fiona E. Pelly, Hattie H. Wright, Claire Palermo Jan 2025

Concept-Based Curriculum: An Evidence-Based Approach To Developing A New Framework For Dietetics Education?, Andrea Begley, Janica Jamieson, Gemma Jenkins, Janeane Dart, Lauren T. Williams, Simone Gibson, Fiona E. Pelly, Hattie H. Wright, Claire Palermo

Research outputs 2022 to 2026

Aims: Concept-based approaches to curricula have been proposed as a solution to this issue, and 56 concepts have been proposed for dietetics curricula. This study aimed to develop a framework for a dietetic concept-based curriculum. Methods: A pragmatic approach was employed by a team of nine experienced Australian dietetic educators. Iterative processes of idea generation, reflection, group discussion, and consensus formation were applied by seven of the academics in a two-day face-to-face workshop and four online meetings to further develop the 56 curriculum concepts previously identified for dietetics by Tweedie et al. The discussions were supported by document analysis and …

Go to article

Infant Diet Recommendations Reduce Ige-Mediated Egg, Peanut, And Cow's Milk Allergies, Summer V.M. Walker, Nina D'Vaz, Rachelle A. Pretorius, Johnny Lo, Claus Christophersen, Susan L. Prescott, Debra J. Palmer Jan 2025

Infant Diet Recommendations Reduce Ige-Mediated Egg, Peanut, And Cow's Milk Allergies, Summer V.M. Walker, Nina D'Vaz, Rachelle A. Pretorius, Johnny Lo, Claus Christophersen, Susan L. Prescott, Debra J. Palmer

Research outputs 2022 to 2026

Background: Meta-analyses of randomized controlled trials have found that introducing eggs and peanuts earlier during infancy reduced egg and peanut allergy risk. Hence, infant feeding advice has dramatically changed from previous recommendations of avoidance to current recommendations of inclusion of common food allergens in infant diets. Objective: To compare the prevalence of IgE-mediated food allergies at 1 year of age between 2 cohorts, before and after infant feeding and allergy prevention guidelines changed. Methods: In cohort 1 (506 infants born 2006-2014), no infant feeding advice was provided to participants. In cohort 2 (566 infants born 2016-2022), when the infants were …

Go to article

Motor Cortex Inhibition And Facilitation Changes Within Two Weeks Of Anterior Cruciate Ligament Reconstruction (Aclr): A Case Series, Colin Sylvester, Ann Maree Vallence, Casey Whife, Peter D'Alessandro, Christopher Latella, Ebonie Rio, Myles C. Murphy Jan 2025

Motor Cortex Inhibition And Facilitation Changes Within Two Weeks Of Anterior Cruciate Ligament Reconstruction (Aclr): A Case Series, Colin Sylvester, Ann Maree Vallence, Casey Whife, Peter D'Alessandro, Christopher Latella, Ebonie Rio, Myles C. Murphy

Research outputs 2022 to 2026

Purpose: Anterior cruciate ligament reconstruction (ACLR) can cause arthrogenic muscle inhibition (AMI) or persistent muscle weakness that impairs physical function and return to sport. Deficits in voluntary activation (one method to measure AMI) are thought to contribute to AMI, however, the specific neurophysiological underpinnings remain inconclusive. The primary objective of this study was to explore changes in intracortical excitability (inhibition and facilitation) of the quadriceps representation in the primary motor cortex pre- and post-ALCR. Our secondary objective was to explore changes in hamstrings intracortical excitability pre- and post-ALCR. Methods: Prospective case-series pre-post-ACLR. Single- and paired-pulse transcranial magnetic stimulation (TMS) was …

Go to article

Sex Differences In The Association Between Episodic Memory Residual Reserve Index And Change In Executive Function, Cheyenne Chooi, Brandon E. Gavett, David Ames, Paul Maruff, Vincent Doré, Victor L. Villemagne, Pierrick Bourgeat, Ying Xia, Colin L. Masters, Ralph N. Martins, Kevin Taddei, Christopher C. Rowe, Michael Weinborn, Stephanie R. Rainey-Smith Jan 2025

Sex Differences In The Association Between Episodic Memory Residual Reserve Index And Change In Executive Function, Cheyenne Chooi, Brandon E. Gavett, David Ames, Paul Maruff, Vincent Doré, Victor L. Villemagne, Pierrick Bourgeat, Ying Xia, Colin L. Masters, Ralph N. Martins, Kevin Taddei, Christopher C. Rowe, Michael Weinborn, Stephanie R. Rainey-Smith

Research outputs 2022 to 2026

Sex differences in cognitive reserve might contribute to females being disproportionately affected by Alzheimer's disease (AD). We investigated sex differences in the protective effects of cognitive reserve, and whether brain beta-amyloid accounts for differences. Older adults (n = 997 from the Australian Imaging, Biomarkers and Lifestyle Study of Ageing) diagnosed as Cognitively Normal, Mild Cognitive Impairment, or AD at baseline were assessed every 18 months for up to a maximum of seven visits. Cognitive reserve was calculated from the variance in episodic memory not explained by demographic or brain measures. Executive functioning (EF) intercept and slope were regressed onto the …

Go to article

Support For Older People Living With Chronic Life-Limiting Illnesses In Rural Ghana, Barbara Adonteng-Kissi, Obed Adonteng-Kissi Jan 2025

Support For Older People Living With Chronic Life-Limiting Illnesses In Rural Ghana, Barbara Adonteng-Kissi, Obed Adonteng-Kissi

Research outputs 2022 to 2026

Summary: This research aims to address formal support needs of informal caregivers (ICs) in the context of long-term care of older people (OP) living with chronic life-limiting illnesses and examine the relationships of ICs of OP with formal support in rural Ghana. We undertook ethnographic interviews with 15 OP; 15 ICs; and 10 healthcare professionals (HPs) after participatory observations during 6 months of fieldwork. This was supported with daily field notes used to collect the needed data and purposively sampled across Gomoa West District in Ghana. The average age of participants was 76 years. Interviews were recorded and transcribed, using …

Go to article

Association Of High-Sensitivity Cardiac Troponin I Levels Below The Sex-Specific 99th Percentile With Late-Life Dementia: The Perth Longitudinal Study Of Ageing Women, Carlos J. Toro-Huamanchumo, Abadi Kahsu Gebre, Tiago Pecanha, Craig Sale, Wai Lim, Elizabeth Byrnes, Ee Mun Lim, Simon Laws, Kun Zhu, Carl Schultz, Richard L. Prince, Blossom C.M. Stephan, Mario Siervo, Joshua R. Lewis, Marc Sim Jan 2025

Association Of High-Sensitivity Cardiac Troponin I Levels Below The Sex-Specific 99th Percentile With Late-Life Dementia: The Perth Longitudinal Study Of Ageing Women, Carlos J. Toro-Huamanchumo, Abadi Kahsu Gebre, Tiago Pecanha, Craig Sale, Wai Lim, Elizabeth Byrnes, Ee Mun Lim, Simon Laws, Kun Zhu, Carl Schultz, Richard L. Prince, Blossom C.M. Stephan, Mario Siervo, Joshua R. Lewis, Marc Sim

Research outputs 2022 to 2026

Background: Elevated high-sensitivity cardiac troponin (hs-cTn) levels are linked with cardiovascular disease and cognitive impairment, both of which are strong risk factors for late-life dementia (LLD). This study examined the association between hs-cTnI levels below the sex-specific 99th percentile for myocardial injury and the incidence of LLD in older women. Methods: 986 community-dwelling women aged ≥70 years without prior LLD and with hs-cTnI < 15.6 ng/L (stratified into quartiles) were included from the Perth Longitudinal Study of Ageing Women. The primary outcome was incident LLD events, including LLD hospitalisation or death, over 14.5 years obtained from linked health records. Associations between hs-cTnI and LLD outcomes were explored using multivariable-adjusted Cox models, as part of restricted cubic splines. Results: At baseline, participants' mean (±SD) age was 75.2±2.7 years. Over 14.5 years of follow-up, LLD events (n=174, 17.7%), hospitalisations (n=155, 15.7%) and deaths (n=68, 6.9%) were recorded. Compared with those in the lowest quartile (Q1, median 3.1 ng/L), women in the highest quartile of hs-cTnI (Q4, median 7.3 ng/L) had a greater risk of developing LLD-related events (adjusted HR: 1.88, 95% CI: 1.22 to 2.91), hospitalisation (adjusted HR: 1.65, 95% CI: 1.04 to 2.64) and death (adjusted HR: 2.27, 95% CI: 1.13 to 4.59), after adjusting for established cardiovascular and dementia risk factors, including apolipoprotein E (APOE) genotype. Conclusion: Among older women, hs-cTnI levels below the sex-specific 99th percentile for myocardial injury were associated with an increased risk of LLD events over 14.5 years. These findings suggest that hs-cTnI may identify older women at higher risk of LLD, capturing both cardiovascular and brain health vulnerability in older age.

Go to article

Establishment Of Reference Intervals For Serum Immunoglobulin G N-Glycosylation Features In Healthy Chinese Adults: A Nationwide Survey In The Framework Of Predictive, Preventive, And Personalized Medicine, Changyu Liu, Yinghao Wang, Xingang Li, Xiaojia Xu, Ruirui Xu, Cuihong Tian, Zhixian Chen, Xinxia Lu, Yuejin Li, Meng Wang, Zhaoyang Tang, Xueyu Chen, Guoyong Ding, Xuerui Tan, Dong Li, Haifeng Hou, Wei Wang Jan 2025

Establishment Of Reference Intervals For Serum Immunoglobulin G N-Glycosylation Features In Healthy Chinese Adults: A Nationwide Survey In The Framework Of Predictive, Preventive, And Personalized Medicine, Changyu Liu, Yinghao Wang, Xingang Li, Xiaojia Xu, Ruirui Xu, Cuihong Tian, Zhixian Chen, Xinxia Lu, Yuejin Li, Meng Wang, Zhaoyang Tang, Xueyu Chen, Guoyong Ding, Xuerui Tan, Dong Li, Haifeng Hou, Wei Wang

Research outputs 2022 to 2026

Background: Immunoglobulin G (IgG) N-glycosylation plays a vital role in the pathogenesis of autoimmune disorders, inflammatory diseases, and viral infections. While various models of serum IgG N-glycosylation have been developed to identify individuals at high risk for relevant diseases, reference intervals (RIs) for the levels of IgG N-glycans have not been established yet. Identifying RIs for serum IgG N-glycans closely associated with biological aging and disease risk contributes to predictive, preventive, and personalized medicine (PPPM/3PM), which results in improvement of patients’ outcomes, enhancement of healthcare efficiency, and in reducing burden of chronic diseases. This study is aimed at defining the …

Go to article

Exercise Parameters To Consider For Achilles Tendinopathy: A Modified Delphi Study With International Experts, Yoann Demangeot, Seth O’Neill, Francis Degache, Amandine Rapin, Umer Asgher, Hakan Alfredson, Rachel Chester, Ruth L. Chimenti, Robert Jan De Vos, Adrian Escriche-Escuder, Kenneth Farnqvist, Bas Habets, Nicola Maffulli, Stig Peter Magnusson, Peter Malliaras, Myles C. Murphy, Craig R. Purdam, Jonathan D. Rees, Ebonie K. Rio, Igor Sancho, Alex Scott, Karin Gravare Silbernagel, Vincent Gremeaux, Francois C. Boyer, Redha Taiar Jan 2025

Exercise Parameters To Consider For Achilles Tendinopathy: A Modified Delphi Study With International Experts, Yoann Demangeot, Seth O’Neill, Francis Degache, Amandine Rapin, Umer Asgher, Hakan Alfredson, Rachel Chester, Ruth L. Chimenti, Robert Jan De Vos, Adrian Escriche-Escuder, Kenneth Farnqvist, Bas Habets, Nicola Maffulli, Stig Peter Magnusson, Peter Malliaras, Myles C. Murphy, Craig R. Purdam, Jonathan D. Rees, Ebonie K. Rio, Igor Sancho, Alex Scott, Karin Gravare Silbernagel, Vincent Gremeaux, Francois C. Boyer, Redha Taiar

Research outputs 2022 to 2026

To assess the level of agreement among experts on the heel raise exercise parameters that influence midportion and insertional Achilles tendinopathy (AT) rehabilitation outcomes. An international expert panel in AT rehabilitation was invited to complete a three-round Delphi survey. In the first two rounds, experts were asked to review a pregenerated list of exercise parameters (based on the heel raise exercise) and rate their perceived influence on rehabilitation outcome, using a 5-point Likert scale. For each parameter, consensus criteria for major influence on rehabilitation were (a) median≥4, (b) ≥75% of scoring 4 or 5 and (c) IQR≤1. The third round …

Go to article

Perception-Based Methods And Beyond: A Current Opinion On How To Assess Static Stretching Intensity, Konstantin Warneke, Anthony J. Blazevich, Daniel Jochum, David G. Behm, Ewan Thomas, Masatoshi Nakamura, José Afonso Jan 2025

Perception-Based Methods And Beyond: A Current Opinion On How To Assess Static Stretching Intensity, Konstantin Warneke, Anthony J. Blazevich, Daniel Jochum, David G. Behm, Ewan Thomas, Masatoshi Nakamura, José Afonso

Research outputs 2022 to 2026

Muscle stretching is widely used in clinical, athletic, and otherwise healthy populations, yet a consensual definition of stretch intensity—a key component of stretch load—does not exist. This is important because the effects of stretch intensity on range of motion and strength are controversial but suggested to affect clinical practice and scientific research. Most commonly, stretch intensity is defined in relation to an individual’s perceived level of discomfort or pain; however, these definitions are problematic for several reasons, including that consensual and objective quantifiable definitions of ‘pain’ and ‘discomfort’ do not exist, perceptions vary widely (and may not be sensed in …

Go to article

The Multifaceted Interplay Between Covid-19-Induced Psychological Stress, Cognitive Flexibility, Emotional Overeating, And Physical Activity Patterns In Adult Women: A Mediated Path Analysis, Siavash Naddafha, Mandana Sangari, Zohreh Eskandari, Robabeh Shahnahadd, Christopher B. Taber Jan 2025

The Multifaceted Interplay Between Covid-19-Induced Psychological Stress, Cognitive Flexibility, Emotional Overeating, And Physical Activity Patterns In Adult Women: A Mediated Path Analysis, Siavash Naddafha, Mandana Sangari, Zohreh Eskandari, Robabeh Shahnahadd, Christopher B. Taber

Research outputs 2022 to 2026

Objective: To determine how COVID-19-related stress influences food consumption and emotional overeating in adult women, and whether cognitive flexibility and physical activity mediate these relationships. Methods: In this cross-sectional study, 303 women (20–50 y) completed validated Persian versions of the COVID Stress Scale-18, Adult Eating Behaviour Questionnaire, Self-Regulation of Eating Behaviour Questionnaire, Cognitive Flexibility Scale, and Rapid Assessment of Physical Activity. Data were collected online via the ISO-27001-certified “Press Line” platform (end-to-end encryption). Chi-square tests and Spearman’s rank correlations were performed in SPSS 19 (α = 0.05). Results: COVID-19 stress was strongly inversely associated with cognitive flexibility (rₛ = – …

Go to article

Validation Status Of Digital Blood Pressure Monitors In Peru: A Comprehensive Assessment With A Validation-Process Algorithm Proposal, Fabian A. Chavez-Ecos, Sandra S. Chavez-Malpartida, Alexander M. Parra-Huaroto, Rodrigo Chavez-Ecos, Kiara Camacho-Caballero, Marcelo Chavez-Ecos, Miguel A. Chavez-Gutarra, Henry Anchante-Hernandez, Carlos J. Toro-Huamanchumo Jan 2025

Validation Status Of Digital Blood Pressure Monitors In Peru: A Comprehensive Assessment With A Validation-Process Algorithm Proposal, Fabian A. Chavez-Ecos, Sandra S. Chavez-Malpartida, Alexander M. Parra-Huaroto, Rodrigo Chavez-Ecos, Kiara Camacho-Caballero, Marcelo Chavez-Ecos, Miguel A. Chavez-Gutarra, Henry Anchante-Hernandez, Carlos J. Toro-Huamanchumo

Research outputs 2022 to 2026

Background In Latin America and the Caribbean (LAC), hypertension is the leading cause of death and disability. Accurate diagnosis requires validated blood pressure measurement devices (BPMD). This study aimed to assess the characteristics and validation status of blood pressure measuring devices available for online purchase within Peru. Methods Between September and November 2023, we performed an electronic search of major retailers and online pharmacies. Devices were classified as validated if they were listed in databases recommended by the 2023 European Society of Hypertension (ESH) Guidelines for the Management of Arterial Hypertension or deemed equivalent by the manufacturer. Validation status was …

Go to article

Advancing Person-Centred Care Through Palliative Care Wa’S Acp Workshops: The Longer-Term Impact, Gertrude G. Phiri, Emma Gunner, Philip Bafile, Davina Porock Jan 2025

Advancing Person-Centred Care Through Palliative Care Wa’S Acp Workshops: The Longer-Term Impact, Gertrude G. Phiri, Emma Gunner, Philip Bafile, Davina Porock

Research outputs 2022 to 2026

Planning for end-of-life and associated decision-making is one of global significance as it impacts the quality of care in palliative care settings, including ensuring that personal preferences are honoured. It is a priority for the Australian health system to use Advance Care Planning (ACP) as it is an effective tool for individuals and their families to make their personal preferences known and implemented. The aim of this project was to evaluate the longer-term impact of the Palliative Care Western Australia (PCWA) ACP workshops. Semi-structured, open-ended questions were used to collect data from 21 participants. Reflexive thematic analysis was used to …

Go to article

Determinants Of Short Interpregnancy Intervals In High-Income Countries: A Systematic Review, J. Dunne, D. Foo, J. Jancey, G. Pereira, B. Kefale, D. G. Belay, G. Dhamrait, A. T. Gebremedhin, K. B. Mruts, S. D. Nyadanu, A. Roy, G. A. Tessema Jan 2025

Determinants Of Short Interpregnancy Intervals In High-Income Countries: A Systematic Review, J. Dunne, D. Foo, J. Jancey, G. Pereira, B. Kefale, D. G. Belay, G. Dhamrait, A. T. Gebremedhin, K. B. Mruts, S. D. Nyadanu, A. Roy, G. A. Tessema

Research outputs 2022 to 2026

Short interpregnancy intervals (IPIs) of <6–18 months are associated with adverse maternal and child outcomes. This study aimed to identify the individual, relationship, community, and societal factors that influence short IPIs in high-income countries. A comprehensive search was undertaken in CINAHL Plus, Ovid/EMBASE, Ovid/MEDLINE, Ovid/PsycINFO, ProQuest, PubMed, Scopus, Web of Science, and Google Scholar for articles published in English from 1st January 1990 to 26th October 2023. Studies were included if they reported an effect estimate of at least one determinant of pregnancy spacing in a high-income country. The quality of the included studies was assessed using the Johanna Briggs Institute Critical Appraisal Tool and Cochrane Risk Assessment Tool. Multi-level factors at the individual, relationship, community, and societal level were systematically identified through the socio-ecological model. This study is registered with PROSPERO (CRD42020176311). Of 2005 unique articles, 220 were identified for full-text review, and 55 met the inclusion criteria representing a total of 27,103,055 women from 13 high-income countries. All the included studies were deemed to be of moderate to high quality. Most of the studies reported determinants of short IPI at the individual level, with non-use of contraception the most common reported factor. Peer influence was a factor at the relationship level, and access to health care and reproductive services were impactful at the community and societal levels, respectively. Future research and efforts should support the development and implementation of policies and practices that support optimum pregnancy spacing from a comprehensive socio-ecological position.

Go to article

Dissemination And Implementation Of Injury Prevention Interventions: A Scoping Review For The Female, Woman And Girl Athlete Injury Prevention (Fair) Consensus, Brooke E. Patterson, Carly D. Mckay, Meghan L. Critchley, Destiny Lutz, Sallie M. Cowan, Nicholas Kolesky, Vanda White, Allison M. Ezzat, Andrew G. Ross, William M. Adams, Eva Ageberg, Clare L. Ardern, Marelise Badenhorst, Molly Coventry, Marc Olivier Dubé, Stacey Emmonds, Libby J. Gracias, K. Alix Hayden, Hanna Lindblom, Merete Møller, Christine Holm Moseid, Nancy Harrington, Dai Sugimoto, Evert Verhagen, Kate K. Yung, Phathokuhle C. Zondi Jan 2025

Dissemination And Implementation Of Injury Prevention Interventions: A Scoping Review For The Female, Woman And Girl Athlete Injury Prevention (Fair) Consensus, Brooke E. Patterson, Carly D. Mckay, Meghan L. Critchley, Destiny Lutz, Sallie M. Cowan, Nicholas Kolesky, Vanda White, Allison M. Ezzat, Andrew G. Ross, William M. Adams, Eva Ageberg, Clare L. Ardern, Marelise Badenhorst, Molly Coventry, Marc Olivier Dubé, Stacey Emmonds, Libby J. Gracias, K. Alix Hayden, Hanna Lindblom, Merete Møller, Christine Holm Moseid, Nancy Harrington, Dai Sugimoto, Evert Verhagen, Kate K. Yung, Phathokuhle C. Zondi

Research outputs 2022 to 2026

Objective: To synthesise evidence related to the dissemination and implementation (D&I) of injury prevention interventions for female, woman and/or girl (female/woman/girl) athletes. Design Scoping review. Data sources MEDLINE, APA PsycInfo, Cochrane Databases for Systematic Review, Cochrane Central Register for Controlled Trials Registry, EMBASE, CINAHL, SPORTDiscus, ERIC, ProQuest Dissertation and Theses Global. Eligibility Primary research including ≥25% female/woman/girl athletes of any age or people working with them (eg, coaches), participating in sports competition and/or performance, were eligible. Papers reporting D&I outcomes (eg, coach knowledge, adoption and maintenance) related to an injury prevention intervention and/or a factor (eg, coach beliefs) associated with …

Go to article

Effects Of Multi-Ingredient Protein Supplementation Combined With Exercise Intervention On Body Composition And Muscle Fitness In Healthy Women: A Systematic Review With Multilevel Meta-Analysis, Chengyu Zhou, Muen Qiu, Zhuo Zeng, Qi Xie, Kai Xu, Henghao Yan, Bo Wang, Bopeng Qiu, Guoxin Shi Jan 2025

Effects Of Multi-Ingredient Protein Supplementation Combined With Exercise Intervention On Body Composition And Muscle Fitness In Healthy Women: A Systematic Review With Multilevel Meta-Analysis, Chengyu Zhou, Muen Qiu, Zhuo Zeng, Qi Xie, Kai Xu, Henghao Yan, Bo Wang, Bopeng Qiu, Guoxin Shi

Research outputs 2022 to 2026

Objectives: This meta-analysis investigated whether multi-ingredient protein supplements (MIPS) combined with exercise improve body composition and muscle fitness in women. It also examined how participant characteristics, training protocols, and supplementation strategies might influence these outcomes. Methods: A systematic search of five electronic databases was conducted through February 2025 to identify randomized controlled trials evaluating the effects of MIPS combined with exercise training on body composition and muscle-related outcomes in women. A multilevel meta-analysis was performed to pool effect sizes, reported as standardized mean differences (Hedges’ g), with heterogeneity assessed through predefined subgroup analyses. Results: Nine randomized controlled trials involving 408 …

Go to article

Estimating The Number Of Hospital Beds For The Care Of Sick And Small Newborns: An Evidence-Based Systematic Approach, Bireshwar Sinha, Mohan Kumar, Deena Thomas, Natalie Strobel, Gagan Gupta, Karen Edmond, M. Jeeva Sankar Jan 2025

Estimating The Number Of Hospital Beds For The Care Of Sick And Small Newborns: An Evidence-Based Systematic Approach, Bireshwar Sinha, Mohan Kumar, Deena Thomas, Natalie Strobel, Gagan Gupta, Karen Edmond, M. Jeeva Sankar

Research outputs 2022 to 2026

Background Current recommendations for neonatal bed requirements are largely assumption-based rather than data-driven. We aimed to estimate the number of beds per 1000 live births needed for the care of small and sick newborns. Methods We first extracted data from studies published between 2018 and May 2023. Then, due to considerable heterogeneity in the data, we performed a meta-analysis using a random effects model to estimate the number of neonatal admissions and the length of stay. We divided the total patient days (admission rate multiplied by the length of stay) by 365 to estimate the annual number of beds per …

Go to article

Integration Of Virtual Simulation Within A Nursing Curriculum: A Mixed Methods Study, Martina Costello, Hugh Davies, Fiona Williams, Michelle Gay, Jennifer Jennings, Joyce Muge-Sugutt, Olivia Gallagher Jan 2025

Integration Of Virtual Simulation Within A Nursing Curriculum: A Mixed Methods Study, Martina Costello, Hugh Davies, Fiona Williams, Michelle Gay, Jennifer Jennings, Joyce Muge-Sugutt, Olivia Gallagher

Research outputs 2022 to 2026

Background: Virtual simulation is a valuable learning tool for health professionals to facilitate knowledge, skills, and confidence. Simulation-based learning in Nursing has increased with advances in digital technologies, embedding diverse virtual modalities. The integration of virtual simulations requires careful consideration of pedagogical approaches and implementation strategies. The vSim® for Nursing platform was integrated into the curriculum of an undergraduate nursing program at an Australian university to enhance clinical learning experiences. Aim: To evaluate the implementation of the vSim® for Nursing learning platform within the second-year curriculum. Methods: A mixed-methods cross-sectional survey design was used, guided by Kirkpatrick's training evaluation model. …

Go to article

Of Scents And Cytokines: How Olfactory And Food Aversions Relate To Nausea And Immunomodulation In Early Pregnancy, Dayoon Kwon, Daniel M.T. Fessler, Delaney A. Knorr, Kyle S. Wiley, Julie Sartori, David A. Coall, Molly M. Fox Jan 2025

Of Scents And Cytokines: How Olfactory And Food Aversions Relate To Nausea And Immunomodulation In Early Pregnancy, Dayoon Kwon, Daniel M.T. Fessler, Delaney A. Knorr, Kyle S. Wiley, Julie Sartori, David A. Coall, Molly M. Fox

Research outputs 2022 to 2026

Background: During pregnancy, the maternal body undergoes extensive physiological adaptations to support embryonic growth, including whole-body remodeling, that may induce odor and food aversions, as well as nausea and vomiting. The biological mechanisms behind odor and food aversions, as well as nausea and vomiting in early pregnancy, remain largely unexplored. Our study investigated associations between these changes and cytokine profiles during pregnancy. Methodology: A cohort of pregnant Latina women in Southern California (n = 58) completed a structured questionnaire on pregnancy "morning sickness"-related symptoms and aversions. Maternal plasma cytokine levels were measured between 5 and 17 weeks' gestation. Results: About …

Go to article

Prognostic Value Of Neutrophil-To-Lymphocyte Ratio, Platelet-To-Lymphocyte Ratio, And Lactate Dehydrogenase Level In Melanoma Patients Treated With Immune Checkpoint Inhibitors, Wynne Wijaya, Muhammad Adnan Khattak, Afaf Abed, Tarek Meniawy, Michael Millward, Elin Gray, Oliver Oey Jan 2025

Prognostic Value Of Neutrophil-To-Lymphocyte Ratio, Platelet-To-Lymphocyte Ratio, And Lactate Dehydrogenase Level In Melanoma Patients Treated With Immune Checkpoint Inhibitors, Wynne Wijaya, Muhammad Adnan Khattak, Afaf Abed, Tarek Meniawy, Michael Millward, Elin Gray, Oliver Oey

Research outputs 2022 to 2026

Introduction: Metastatic melanoma carries a poor prognosis. Immune checkpoint inhibitors (ICIs) have improved outcomes, but responses remain variable, highlighting the need for simple prognostic biomarkers. Inflammatory markers such as neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and lactate dehydrogenase (LDH) reflect tumour burden and inflammation, though their clinical utility is unstandardised. Methods: We retrospectively analysed 103 metastatic melanoma patients treated with anti-PD-1 monotherapy at two centres in Western Australia (2014–2020). Baseline NLR, PLR, and LDH were assessed within 30 days pre-treatment. Outcomes included clinical benefit, progression-free survival (PFS), and overall survival (OS). Results: Poor ECOG performance status (PS ≥2) (RR 2.39, …

Go to article

Psychotropic Medications Versus Non-Pharmacologic Approaches For Managing Behavioural And Psychological Symptoms In Australian Aged Care Residents With Dementia: General Practitioners’ And Physicians’ Perspectives, Hunduma D. Ayeno, Mustafa Atee, Gizat M. Kassie, Vijayaprakash Suppiah, Imaina Widagdo, Tuan A. Nguyen Jan 2025

Psychotropic Medications Versus Non-Pharmacologic Approaches For Managing Behavioural And Psychological Symptoms In Australian Aged Care Residents With Dementia: General Practitioners’ And Physicians’ Perspectives, Hunduma D. Ayeno, Mustafa Atee, Gizat M. Kassie, Vijayaprakash Suppiah, Imaina Widagdo, Tuan A. Nguyen

Research outputs 2022 to 2026

Background: Psychotropic medications are often inappropriately prescribed for behavioural and psychological symptoms of dementia (BPSD), posing significant risks such as falls, stroke and death. Although non-pharmacological interventions (NPIs) are the first-line treatment for BPSD, their use in practice remains limited. Objectives: This study explored general practitioners’ (GPs’) and physicians’ perspectives on using psychotropic medications compared to NPIs for managing BPSD in Australian residential aged care homes (RACHs). Design: Semi-structured online in-depth interviews were conducted with GPs and physicians managing BPSD in Australian RACHs. Methods: The interviews were audio-recorded, transcribed and analysed using inductive thematic analysis, with transcripts coded using NVivo …

Go to article

First Prev Next Last