Medicine and Health Sciences Commons^™

Assessing Impact Of Molecular Diagnostics On Time To Optimal Antibiotic Therapy In Pediatric Staphylococcal Bacteremia, Manith Humchad, Kelly Williamson

Williams Honors College, Honors Research Projects

Timely optimization of antibiotic therapy is critical in pediatric patients with blood infections, particularly those caused by Staphylococcus aureus. This retrospective study evaluated the impact of molecular diagnostics on time to optimal therapy and discontinuation of unnecessary antibiotics at Akron Children’s Hospital from January 2020 to April 2023. Patients with Methicillin-resistant Staphylococcus aureus (MRSA) were more likely to be on appropriate empiric therapy (i.e. vancomycin) before culture results, whereas Methicillin-sensitive Staphylococcus aureus (MSSA) cases were de-escalated to beta-lactams. The median time to optimal therapy was 3.7 hours for episodes of MSSA. Infectious Disease (ID) consultation significantly influenced antibiotic management, with …

Review Of Research On Relative Energy Deficiency In Sport (Red-S), Paige Mcmaster

Williams Honors College, Honors Research Projects

The following research article review serves to summarize and evaluate peer-reviewed research articles on the topic of Relative Energy Deficiency in Sport (RED-S). The paper will cover RED-S's effect on males versus females, endurance athletes versus non-endurance athletes, recreational athletes versus competitive athletes, and different age groups. Methodology includes strategically reviewing current literature and providing common themes or key points. The goal is to effectively summarize the subject of RED-S, provide in-depth understanding of the condition, and establish the need for education to prevent or reduce the incidence of RED-S.

A Framework For Trauma-Informed Mediation: A Heart And Mind Approach To Conflict Resolution, Michael Saini, Raheena Lalani Dahya, Shely Polak

Cardozo Journal of Conflict Resolution

Unresolved trauma histories can have both short and long-term consequences on children and parents' overall functioning. Using a trauma-informed approach to mediation, we first briefly highlight the impactofadversechildhood experiencesandunresolvedtraumasonadults. We then consider the various vulnerabilities and activations presented within mediation and the fundamental principles of trauma-informed mediation to assist parties in remaining within the "window of tolerance" during the mediation. Trauma-informed mediation is an approach that encourages mediators to be aware of potential trauma activations and to engage in compassionate practices to allow parties to engage within their own individualized "window of tolerance" to resolve disputes. We explore the unique …

Environmental Pollution And Early-Life Metabolic Programming, Lisa Koshko

Wayne State University Dissertations

Substantial evidence demonstrates that parental pollutant exposures can induce harmful health effects in the offspring, including the predisposition to Type II Diabetes. As rates of Type II Diabetes continue to rise in younger populations, a crucial gap lies in understanding the role of parental influence in the etiology of later-life metabolic disease. Therefore, the central goal of this work was to determine how early life exposure to smoking level benzene, an endocrine-disrupting air pollutant, affects the metabolic health of offspring, and to identify potential developmental mechanisms involved in disease susceptibility. This goal was achieved using two models of early life …

The Category Is: Body: A Pcsim Approach To Culture-Specific Bid Healing Programming For Bgcm, Gabriel A. Delong

Wayne State University Dissertations

Black gay cismen (BGCM) are among the highest population demographics to experience body image dissatisfaction (BID) and among the least likely to seek healing programming. Culture-specific experiences such as sexual racism have been linked to body image dissatisfaction among BGCM. While the harmful experiences of sexual racism have been studied among BGCM, body image healing programming continues to address the needs of predominantly White straight ciswomen. Additionally, medical mistrust, identity preservation, and culturally incongruent healing practices have been linked to reasons BGCM are reluctant to seek healing practices. This dissertation aims to address the gap in existing literature by employing …

Artificial Intelligence System Accurately Detects Fetal Ultrasound Findings Suspicious For Major Congenital Heart Defects, Carolyn M. Zelop, Jennifer Lam-Rachlin, Alisa Arunamata, Rajesh Punn, Sarina K. Behera, Matthias Lachaud, Nadine David, Greggory R. Devore, Andrei Rebarber, Sara Garmel

Conference Presentation Abstracts

Objective: Prenatal detection of congenital heart defects (CHD) improves patient outcomes. Despite advances in imaging techniques and equipment, prenatal diagnosis remains low. We evaluated the accuracy of an artificial intelligence (AI) system to detect 2nd trimester (2T) ultrasound studies suspicious for CHD. Study Design: The AI system analyzes all grayscale 2D ultrasound cines of a study and detects 8 morphological findings suspicious for CHD. The findings were selected such that most major forms of CHD would feature at least one such finding, and the presence of any of these would flag the study for referral for further examination. We retrospectively …

Long Term Outcomes In Pediatric Patients With Moyamoya Syndrome And Moyamoya Disease Treated With Encephaloduroarteriosynangiosis (Edas) + Pial Synangiosis: A Single Institution Experience, Matthew Jarrell, Sage Rahm, Nadine Bradley, Anastasia Smith, Jesse Jones, James M. Johnston

UAB Huntsville Research Day - All Presentations

2025 oral presentation

The Role Of Cortisol And Cortisone Levels In Atrial Fibrillation, Jacob Greer, Peng Li, Tanja Dudenbostel

UAB Huntsville Research Day - All Presentations

2025 research poster

Racial Differences In Urinary Cortisol Levels And Left Ventricular Hypertrophy In Patients With Resistant Hypertension, Soumyadeep Bag, Peng Li, Jacob Greer, Tanja Dudenbostel

UAB Huntsville Research Day - All Presentations

2025 research poster

Breaking Barriers: Improving Access To Community Resources In Primary Care, Dejah Patton, Victoria Deal, Azeline Arcenal, Meredith Lewis

UAB Huntsville Research Day - All Presentations

2025 research poster

Case Report: Moyamoya Disease In An African American Woman, Mabel Berg, Ahmed Ali, Farrah Ibrahim

UAB Huntsville Research Day - All Presentations

No abstract provided.

Testosterone Therapy For Depression In Men: High Potential, Limited Evidence, Tina Huang, Mina Takahashi, Luis Benitez, Anupama Yedla, Janaki Nimmagadda, Clinton Martin

UAB Huntsville Research Day - All Presentations

No abstract provided.

Treatment Of Histoplasmosis With Posaconazole In The Setting Of A Severe Itraconazole Hypersensitivity Reaction: A Case Report, Kinsey M. Johannemann, Megan Z. Roberts, Samir Allos, Madeline Belk, Spencer H. Durham, Jonathan Edwards

UAB Huntsville Research Day - All Presentations

No abstract provided.

Neurosarcoidosis Presenting As Isolated Hypogonadotropic Hypogonadism, Ahmed Qaedi, Hope Lackey, Kaehler Roth, Farrah Ibrahim

UAB Huntsville Research Day - All Presentations

No abstract provided.

Gone Glomeruli : A Case Of Severe Crescentic Iga Nephropathy, Aesha Patel, Hinal Rathi, Hope Lackey, Emily Custer, Alan Baggett

UAB Huntsville Research Day - All Presentations

No abstract provided.

The Quality-Of-Life Benefits And Risk Of Isotretinoin (Accutane) In Acne Treatment: A Systematic Review, Noelia Valencia Zuniga

Honors Undergraduate Theses

Acne vulgaris is a prevalent dermatological condition, particularly affecting adolescents and young adults. While often treated as a cosmetic issue, acne can significantly impair a patient's mental health and overall quality of life (QoL). Isotretinoin, commonly known as Accutane, is widely regarded as the most effective treatment for severe and persistent acne. However, its use is controversial due to a range of potential side effects, including psychiatric symptoms, teratogenicity, and other systemic complications. To better understand the risk-benefit profile of isotretinoin in acne treatment, we conducted a systematic review, focusing on the QoL benefits and risks associated with its use. …

Post-Incident Debriefings For Pediatric Intensive Care Nurse Burnout A Scoping Review, Sulah Emilie Monize

Honors Undergraduate Theses

Burnout is prevalent among pediatric intensive care unit (PICU) nurses, impacting between 42-77% of them. High emotional burden, physical demand, and cognitive overload contribute to significant PICU nurse burnout prevalence. Burnout is linked to increased job turnover, compromised patient care, and decreased staff mental well-being. Addressing burnout is crucial to ensure patient safety and maintain care quality. Burnout in adult ICU nurses is well documented but less so with PICU nurses, and they face stressors unique to their setting, such as a vulnerable patient population and unique dynamics with families and providers. This scoping review includes 9 articles examining the …

Examining The Association Between Perceived Stigma And Mental Health Help-Seeking Behavior Among Racial/Ethnic Minority Students In Health Professions Education, Camila A. Agurto

Honors Undergraduate Theses

Racial and ethnic minority (REM) students in health professions programs in the U.S. have considerable mental health issues. Still, they are less likely to access mental health services when compared to their White peers. The stigma they face, such as —public stigma, self-stigma, or intersectional stigma, may serve as a barrier to help-seeking. Although there is increasing recognition of the barriers to mental health care experienced by these students, there is no systematic understanding of how perceived stigma associated with mental health issues affects mental health help-seeking by REM students enrolled in health professions education. This systematic literature review aims …

Exploring The Public Health Agency Of Canada’S And The Ontario Government’S Vaccine-Related Crisis Communication On X During The Covid-19 Pandemic, Sheraza Burney, Lorie Donelle Phd, Rn, Fcan, Anita Kothari

Publications

Crisis communication strategies must be tailored to the unique nature of social media. In response to the COVID-19 pandemic, public health agencies have widely used social media to address vaccine hesitancy and misinformation. This research utilized the social media pandemic communication model to describe the key themes disseminated through the Ontario government and the Public Health Agency of Canada’s vaccine-related crisis communication on X (formerly Twitter). Between 27 January 2020 and 6 April 2021, 1271 posts related to COVID-19 vaccination were collected from three official government X accounts——two from the province of Ontario and one from Canada. Posts were analyzed …

Passive Remote Monitoring Technologies’ Influence On Home Care Clients’ Ability To Stay Home: Multiprovincial Randomized Controlled Trial, Lorie Donelle Phd, Rn, Fcan, Bradley Hiebert, Grace Warner, Michael Reid, Jennifer Reid, Salimah Shariff, Emily Richard, Sandra Regan, Lori Weeks, Kathleen Ledoux

Publications

Background: Researchers in Nova Scotia and Ontario, Canada, implemented a passive remote monitoring (PRM) model of home care unique to their health system contexts. Each PRM model integrated tailored PRM devices (eg, motion sensors, cameras, and door alarms) into home care patients’ residences with the aim of linking patients, family and friend caregivers, and health care providers to support older adults’ aging in place. Objective: The purpose of this study was to examine the use of PRM technologies in the home to support older adults’ safe aging in place and avoidance or delay of higher levels of care. Methods: This …

Examining Racial Discrimination Index And Black-Years Of Potential Life Lost (Ypll) In South Carolina: A Real-Time Social Media Research, Yunqing Ma, Peiyin Hung Ph.D, Xiaotong Shen, Zhenlong Li, Curisa Tucker Phd, Rn, Jiajia Zhang Ph.D.

Publications

Purpose: Despite efforts to reduce health disparities, Black Americans still face higher mortality rates than Whites. Racism has been recognized as a significant social determinant of health. Using social media data, human-being qualitative coding, and AI, we created a county-level racial discrimination index, exploring its association with years of potential life lost (YPLL) rates. Methods: Through human-AI collaborative approaches using X/Twitter data, we calculated yearly county-level racial discrimination index (RDI)—number of racial discrimination posts per 100,000 in-county non-duplicated posts and examined the relationship between RDI terciles and YPLL per 100,000 non-Hispanic Black individuals. Annual data for the covariates were derived …

Self-Determined Strategies For Physical Activity Motivation Among Women With Polycystic Ovary Syndrome, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Cynthia Corbett Phd, Rn, Faan, Bernardine M. Pinto Phd, Fapa, Fsbm, Fabmr, Michael D. Wirth Msph, Phd, Face, Robin M. Dawson Phd, Rn, Cpnp-Pc

Publications

BACKGROUND: According to clinical practice guidelines for polycystic ovary syndrome, first-line treatment includes performing 150 min of moderate-to-vigorous physical activity on most days of the week plus at least 2 days of resistance training. However, < 40% of women with polycystic ovary syndrome engage in regular physical activity, and about 60% are sedentary. Research evidence supports theory-informed physical activity interventions to improve motivation for physical activity. This study examined the fit of a behavioral change theory for women with polycystic ovary syndrome. OBJECTIVES: The purposes of this qualitative study were to analyze physical activity barriers through the lens of self-determination theory and identify motivational strategies that may promote initiation and maintenance of physical activity among women with polycystic ovary syndrome. DESIGN: The study involved a qualitative, descriptive design using theory-driven thematic analysis. METHODS: After emailing a demographic questionnaire and Personal Health Questionnaire-8 to screen for depressive symptoms, participants (n = 7) met three times via Zoom during the summer of 2021. Meetings were audio-recorded, transcribed, and analyzed. RESULTS: Participants were aged 33.9 (±8.1) years, premenopausal, mostly White (71%), educated (100% with at least some college), employed full-time (86%), and married (86%) with a mean depressive symptoms score of 6.4 (±3.4) indicating mild depression. Strategies such as a buddy system, physician support, technology, and behavioral change techniques are necessary to meet the psychological needs of autonomy, competence, and relatedness among women with polycystic ovary syndrome to help increase exercise motivation. CONCLUSION: Findings supported the use of self-determination theory by emphasizing that the social context of polycystic ovary syndrome can undermine physical activity behavior. Thus, physical activity interventions should consider the social context, peer support system, and mental health status of women with polycystic ovary syndrome, and include tailored programs and motivational strategies to help meet the psychological needs of autonomy, competence, and relatedness.

“I Feel Like It Gets Worse As I Get Older”: Perspectives Of Peri-Postmenopausal Women With Pcos, Pamela J. Wright Phd, Ms, Med, Rn, Cen, Cynthia F. Corbett Phd, Rn, Faan, Robin M. Dawson Phd, Rn, Cpnp-Pc, Charlotte Burts

Publications

Introduction: Polycystic ovary syndrome (PCOS) is a chronic endocrinopathy that transcends the reproductive years. Peri-postmenopausal women with PCOS remain at cardiometabolic risk or subsist with established comorbidity while continuing to contend with persistent PCOS signs and symptoms such as hirsutism. Evidence based information for peri-postmenopausal women with PCOS is scant. The purpose of this qualitative study was to explore the physical, psychosocial, and healthcare perspectives of peri-postmenopausal women with PCOS.

Methods: Peri-postmenopausal women with PCOS aged ≥43 years (n = 29) were recruited using ResearchMatch to participate in a virtual interview. Interviews were conducted using a semi-structured guide. The interviews …

Exploring Maternal Grief And Shame In Addiction Recovery For Pregnant And Early Parenting Women Using Community-Based Participatory Research: A Qualitative Descriptive Study, Phyllis Raynor Phd, Aprn, Pmhnp-Bc, April Hutto, Khushi Patel, Amber Goforth, Cynthia Corbett Phd, Rn, Faan, Delia West Phd, Kacey Eichelberger, Constance Guille, Nicole Nidey, Lori Vick Phd, Mat, Rn, Anef, Alain Litwin

Publications

Introduction: Little research has explored the constructs of grief and shame-proneness for pregnant and early parenting women seeking recovery from substance use disorders (SUD) and the impact on parents’ and children's well-being. Purpose: This study aimed to explore the contexts of reported guilt and shame and the associations with grief and loss among pregnant and early parenting women in SUD recovery.

Methods: Using a community based participatory research (CBPR) approach, we conducted in-depth interviews with 30 pregnant and early parenting women with SUD who were recruited from a residential drug recovery facility in the Southeastern United States. A qualitative descriptive …

Navigating “Being Seen”: Experiences Of Older Adult Arab Immigrants And Family Caregivers Accessing Health Care Services In Ontario, Selma Tobah, Lorie Donelle Phd, Rn, Fcan, Jodi Hall, Lloy Wylie, Sandra Regan

Publications

Immigrants to Canada face unique barriers to accessing health care including communication barriers, socioeconomic limitations, and a lack of health care system navigation knowledge. Arabs in particular face mainstream negative attitudes, propagated through political discourses as well as entertainment media. We sought to understand how older adult Arab immigrants and family caregivers accessed and experienced health care in Ontario. We conducted a critical constructivist grounded theory, using Charmaz’s approach to grounded theory. A critical constructivist grounded theory method asks not only “what” social processes are happening and “how” but also “why” and “who” benefits. Both older adult immigrant Arabs and …

Femtech In Context: A Critical Conceptual (Re)View, Danica Facca, Jodi Hall, Gail Teachman, Joanna Redden, Lorie Donelle Phd, Rn, Fcan

Publications

Emerging as a commercial category in 2016, ‘femtech’ has been publicly celebrated as a category of consumer-based digital health technologies designed to support the unmet and systemically marginalized health needs of women in areas such as menstruation, fertility, pregnancy, postpartum, and menopause, through data-driven apps, wearables, and self-diagnostic tools. Since its emergence, the term femtech has become culturally significant and has taken on a life of its own across commercial, public, and healthcare discourses. Despite the growth of femtech scholarship, clarity is lacking on how different disciplines have challenged the assumptions about sex, gender, health, technology, and innovation that shape …

The Association Between Social Determinants Of Health And Hiv Risk Behaviors And Hiv Testing Among Sexual And Gender Minority Individuals: A National Survey Study, Edith Nnenna Utaka, Xueying Yang Ph.D., Fanghui Shi, Huiyi Xia, Qingyang Li, Brooks Yelton Ma, Lmsw, Daniela Friedman Ph.D., Lorie Donelle Phd, Rn, Fcan, Xiaoming Li Ph.D.

Publications

Social determinants of health (SDOH) predispose Sexual and Gender Minority (SGM) individuals to HIV infection through risky behaviors and less HIV testing. This study used data from the 2022 Behavioral Risk Factor Surveillance System (BRFSS) survey to evaluate the association between composite measures of SDOH and HIV risk behaviors and HIV testing among adult SGM population in the US. SGM individuals were identified through two questions that asked about respondents’ sexual orientation and gender identity. Two primary outcomes of interest were HIV testing behavior and HIV risk behavior. SDOH was measured by ten items which were summed to get a …

Complex Role Of Digital Health Literacy In Awareness And Use Of Digital Sexually Transmitted And Blood-Borne Infections Testing: A Structural Equation Modelling Analysis Of The 2022 Getcheckedonline Survey, Ihoghosa Iyamu, Pierce Gorun, Sofia Bartlett, Geoffrey Mckee, Lorie Donelle Phd, Rn, Fcan, Hsiu Ju Chang, Rodrigo Sierra-Rosales, Devon Haag, Heather Nicole Pedersen, Nathan John Lachowsky, Catherine Worthington, Troy Grennan, Daniel Grace, Mark Gilbert

Publications

Background Although digital health literacy (DHL) is recognised as a determinant of access to digital sexually transmitted and blood-borne infection (STBBI) testing, empirical evidence about its contribution to access disparities remains limited. We applied multidimensional DHL measures to examine inequities in awareness and use of GetCheckedOnline, British Columbia’s (BC) publicly funded digital STBBI testing service. Methods We analysed data from GetCheckedOnline’s 2022 community survey of English-speaking BC residents aged ≥16 years who were sexually active in the past year. Outcomes were awareness and use of GetCheckedOnline (yes/no). DHL was measured using latent factors from the eHealth Literacy Scale: Information Navigation, …

Impact Of Online Interactive Decision Tools On Women’S Decision-Making Regarding Breast Cancer Screening: Systematic Review And Meta-Analysis, Patricia Villain, Laura Downham, Alice Le Bonniec, Charlotte Bauquier, Olena Mandrik, Tom Nadarzynski, Lorie Donelle Phd, Rn, Fcan, Raúl Murillo, Eleni L. Tolma, Sonali Johnson, Patricia Soler-Michel, Robert Smith

Publications

Background: The online nature of decision aids (DAs) and related e-tools supporting women’s decision-making regarding breast cancer screening (BCS) through mammography may facilitate broader access, making them a valuable addition to BCS programs. Objective: This systematic review and meta-analysis aims to evaluate the scientific evidence on the impacts of these e-tools and to provide a comprehensive assessment of the factors associated with their increased utility and efficacy. Methods: We followed the 2020 PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines and conducted a search of MEDLINE, PsycINFO, Embase, CINAHL, and Web of Science databases from August 2010 to …

Development And Validation Of A Revised Multidimensional Digital Health Literacy Scale: Secondary Analysis Using Cross-Sectional Data From The 2022 Getcheckedonline Community Survey In British Columbia, Canada, Ihoghosa Iyamu, Pierce Gorun, Hsiu Ju Chang, Rodrigo Sierra-Rosales, Devon Haag, Heather Pedersen, Sofia Bartlett, Nathan Lachowsky, Geoffrey Mckee, Catherine Worthington, Troy Grennan, Lorie Donelle Phd, Rn, Fcan, Daniel Grace, Mark Gilbert

Publications

Background: Digital technologies are reshaping health care, making digital health literacy (DHL) a critical competency for navigating online health information. Although widely conceived and measured as a unidimensional measure of DHL, the literature increasingly supports a multidimensional framing of the eHealth Literacy Scale (eHEALS). Studies propose alternative factor structures that can better inform population-level interventions, but these studies have not accounted for the ordinal nature of eHEALS response data. Objective: This study aimed to identify and validate an alternate multidimensional structure of eHEALS accounting for its ordinal response scale. Methods: Data were drawn from the 2022 GetCheckedOnline community survey of …