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Full-Text Articles in Medicine and Health Sciences

Preliminary Evaluation Of A Brief Intervention To Enhance Trauma-Informed Attitudes Among Educators And School Mental Health Counselors, Cheri Shapiro, Kara Lee, Courtnie Collins, Tristan Collier, Carl Sorensen Jan 2025

Preliminary Evaluation Of A Brief Intervention To Enhance Trauma-Informed Attitudes Among Educators And School Mental Health Counselors, Cheri Shapiro, Kara Lee, Courtnie Collins, Tristan Collier, Carl Sorensen

Publications

Professional development training designed to advance knowledge of the impacts of trauma and trauma-responsive practices for educators and counselors in schools and mental health settings have become common. Given the popularity of these training approaches, it is important to understand the potential impact on trauma-informed attitudes and beliefs. This descriptive, exploratory study examined changes in traumainformed care attitudes as a function of participating in a novel intervention designed to support trauma-informed practices in a sample of elementary school educators, administrators, and school mental health counselors (n=194) from one state in the Southeastern US. Positive changes in trauma-informed attitudes from pre …


Answering Our Call To Care: Introduction To The Special Issue On Long Covid, Todd E. Davenport Jan 2025

Answering Our Call To Care: Introduction To The Special Issue On Long Covid, Todd E. Davenport

Pacific Faculty Work

No abstract provided.


Why The Museum Matters To Honors, Mimi Killinger Jan 2025

Why The Museum Matters To Honors, Mimi Killinger

Honors in Practice Online Archive

Using classroom displacement and pandemic pivoting during COVID as a touchstone, author presents ways in which museums complement and reinforce pedagogical goals in honors. Community and campus museums offer immediate and innovative teaching opportunities that require minimal technology, present diverse viewpoints and cultural perspectives, and foster visual and cultural literacies. Demonstrating how teaching within a museum aligns with the educational mission of her home institution, author suggests that these spaces can be creative, collaborative, and engaging learning locations for honors colleges and programs throughout the country. Detailed descriptions of curated collections are provided.


Building Place-Based Experiential Learning Into The Honors Curriculum At Ohio University, Geoffrey L. Buckley, Nicole Finnicum, Michelle O'Malley, Jennifer Bowie, Yolonda Youngs Jan 2025

Building Place-Based Experiential Learning Into The Honors Curriculum At Ohio University, Geoffrey L. Buckley, Nicole Finnicum, Michelle O'Malley, Jennifer Bowie, Yolonda Youngs

Honors in Practice Online Archive

Observing the demand for interdisciplinary experiential learning opportunities post-COVID, authors present a place-based curriculum in honors. Workshop-style special topics classes provide students with an immersive and flexible learning environment, energize faculty, and engage alumni and community partners. Coursework, fieldwork, internships, and study abroad opportunities all contribute to the development of an informed and engaged citizenry. Authors address challenges in funding, access, and equity, and they suggest ways these challenges might be met.


Gait During Community Ambulation And Laboratory-Based Walking In People With Mild Traumatic Brain Injury, Prokopios Antonellis, Jae W. Lee, Peter C. Fino, Margaret M. Weightman, Siting Chen, Margaret Stojak, Mark E. Lester, Carrie W. Hoppes, Leland E. Dibble, Laurie A. King Jan 2025

Gait During Community Ambulation And Laboratory-Based Walking In People With Mild Traumatic Brain Injury, Prokopios Antonellis, Jae W. Lee, Peter C. Fino, Margaret M. Weightman, Siting Chen, Margaret Stojak, Mark E. Lester, Carrie W. Hoppes, Leland E. Dibble, Laurie A. King

Physical Therapy Faculty Publications

Background: Gait impairments are common in individuals with mild traumatic brain injury (mTBI), presenting in the acute phase and often persisting in subtle ways over time. Despite the prominence of laboratory gait evaluations, a comprehensive understanding of gait deficits post-mTBI necessitates the examination of various gait domains in real-world environments. Assessing gait during a community ambulation task (CAT) may capture real-world challenges and influence focused interventions or rehabilitation in individuals with mTBI.

Research Question: The aim of the study was to compare gait performance across independent gait domains in individuals with and without mTBI using wearable sensors during both the …


Behavioral Health Training For Integrated Behavioral Health: A Delphi Study, Nicholas Schmoyer, Lisa Corbin, Jessica Huffman, Gülşah Kemer Jan 2025

Behavioral Health Training For Integrated Behavioral Health: A Delphi Study, Nicholas Schmoyer, Lisa Corbin, Jessica Huffman, Gülşah Kemer

Counseling & Human Services Faculty Publications

Using a classical Delphi design, the authors used an interdisciplinary panel of behavioral health experts in integrated behavioral health (IBH) to identify foundational skills and knowledge counselor educators need to teach clinical mental health counselors for IBH practice. Eighty-eight statements were identified. Implications are provided for counseling and other behavioral health educators.


Confidentiality In Addiction Treatment: Navigating 42 Cfr Part 2 Within Human Services, Chaniece Winfield, Jessica Huffman Jan 2025

Confidentiality In Addiction Treatment: Navigating 42 Cfr Part 2 Within Human Services, Chaniece Winfield, Jessica Huffman

Counseling & Human Services Faculty Publications

Recent federal legislation, including the Mental Health Parity and Addiction Equity Act (MHPAE) and the Comprehensive Addiction and Recovery Act (CARA), has placed greater emphasis on quality integrated health care, with a focus on access, treatment options, and evidence-based practices. Changes to Federal 42 CFR privacy protections also impact individuals seeking substance use disorder treatment, either as a primary diagnosis or comorbidity. Human service professionals, as generalists in the behavioral health field, provide vital treatment, recovery, and prevention services for individuals with substance use and addictive disorders. This paper explores the implications of these legislative changes, particularly regarding privacy protections …


The Nohs 2024 Code Of Ethics Update, Kevin C. Snow, Christian Williams, Ed Neukrug, Kristin Barker, Kristin Ballard, Braxton A. Morrison, Leslie C.M. Mcclane, Meghan N. Morgan, Stephanie Collins Jan 2025

The Nohs 2024 Code Of Ethics Update, Kevin C. Snow, Christian Williams, Ed Neukrug, Kristin Barker, Kristin Ballard, Braxton A. Morrison, Leslie C.M. Mcclane, Meghan N. Morgan, Stephanie Collins

Counseling & Human Services Faculty Publications

The NOHS Ethics committee engaged in a revision of the Ethical Standards for Human Services Professionals (2024). This update focused on significant changes in the field of human services as they relate to a broad group of human services professionals. The article explores interviews with key members of the revision committee sharing their thoughts on the necessity for the current revision and the ever-present importance for human service professionals to understand and engage with the NOHS ethics code as an essential living document for the benefit of client well-being, to promote the integrity of the human services profession, and to …


Navigating Recovery: Insights From Distance Learning Human Services Students' Abstinence Experience, Chaniece Winfield, Jill Kivikoski, Catalina Kraft Jan 2025

Navigating Recovery: Insights From Distance Learning Human Services Students' Abstinence Experience, Chaniece Winfield, Jill Kivikoski, Catalina Kraft

Counseling & Human Services Faculty Publications

With the rise in overdose and problematic drug use in the United States, it is crucial to develop competent human service practitioners in addiction treatment and recovery settings. This qualitative study explores the virtual abstinence experience of distance learning human services students, using Mezirow’s transformative learning theory to examine how a 21-day experiential abstinence prompts critical reflection and perspective transformation. The study investigates the socio-emotional and physiological factors influencing participants' progress toward sobriety, including cravings, withdrawal, isolation, and relapse triggers. Findings highlight how participants' critical reflection leads to a deeper understanding of addiction and recovery, as well as an enhanced …


Hemifacial Spasm Due To Dolichoectasia Of Vertebral And Basilar Arteries, Meena Iyer, Shasthara Paneyala Dr. Jan 2025

Hemifacial Spasm Due To Dolichoectasia Of Vertebral And Basilar Arteries, Meena Iyer, Shasthara Paneyala Dr.

Digital Journal of Clinical Medicine

Dolichoectasia refers to the non-focal dilatation and tortuosity of arteries, primarily affecting the vertebral and basilar arteries due to severe tunica intima degeneration. It is associated with genetic predisposition and atherosclerosis, leading to vessel wall weakening. Patients may remain asymptomatic or develop neurological deficits due to mass effect. We report a case of a 60-year-old male presenting with hemifacial spasm secondary to vertebral artery dolichoectasia. Magnetic Resonance Angiography (MRA) revealed ectatic and tortuous basilar and vertebral arteries, with the left vertebral artery compressing the left facial nerve complex. Using Smoker’s criteria, a diagnosis of dolichoectasia was confirmed. Dolichoectasia-induced hemifacial spasm …


Comparison Of The Effectiveness Of Preoperative Dexmedetomidine Nebulization Versus Lignocaine Nebulization In Attenuation Of Stress Response During Direct Laryngoscopy And Endotracheal Intubation In Elective Surgeries Under General Anaesthesia: A Randomised Control Study At A Tertiary Care Hospital, Mandya, Sumayya E., Kiran A V., Santhosh M C B., Shivakumar G Jan 2025

Comparison Of The Effectiveness Of Preoperative Dexmedetomidine Nebulization Versus Lignocaine Nebulization In Attenuation Of Stress Response During Direct Laryngoscopy And Endotracheal Intubation In Elective Surgeries Under General Anaesthesia: A Randomised Control Study At A Tertiary Care Hospital, Mandya, Sumayya E., Kiran A V., Santhosh M C B., Shivakumar G

Digital Journal of Clinical Medicine

Introduction: Direct laryngoscopy and tracheal intubation are known to provoke harmful stimuli that can lead to transient, unpredictable, and variable hemodynamic alterations, primarily due to heightened sympathoadrenal activity.1 Various pharmacological agents have been explored to mitigate this stress response; however, none have emerged as optimal.2

Aim: This study aims to compare the effects of nebulized dexmedetomidine in comparison to nebulized lignocaine on the hemodynamic stress response during direct laryngoscopy and tracheal intubation, including any adverse effects in patients undergoing general endotracheal anesthesia.

Materials and Methods: Informed consent was obtained from 60 patients aged 18 to …


Lymphoma Chronicles: Insights From A Distinct Hodgkin's Lymphoma Case Report, Srirangam Shankaralingam, Vibha Nagaragatta Jan 2025

Lymphoma Chronicles: Insights From A Distinct Hodgkin's Lymphoma Case Report, Srirangam Shankaralingam, Vibha Nagaragatta

Digital Journal of Clinical Medicine

Hodgkin lymphoma (HL) is a kind of lymphatic malignancy distinguished by the presence of Reed-Sternberg cells. It often manifests as painless lymphadenopathy and systemic symptoms (B symptoms and can affect a variety of lymphoid tissues. The causes of HL are complicated and include genetic predisposition, environmental conditions and viral infections, particularly the Epstein-Barr virus (EBV). The diagnosis is primarily based on histological evaluation of lymph node samples, with immunophenotyping assisting classification. Herein, we report a case of classical Hodgkin’s lymphoma (HL) in an otherwise healthy 31-year-old male who had a mass per abdomen for a year and recently noticed a …


Felt Need For Psychiatry Clubs In Medical Colleges To Enhance Teaching-Learning, Aditya Rao, Sheryl Agarwal, Sharanya Bose, M Kishor Jan 2025

Felt Need For Psychiatry Clubs In Medical Colleges To Enhance Teaching-Learning, Aditya Rao, Sheryl Agarwal, Sharanya Bose, M Kishor

Digital Journal of Clinical Medicine

Mental health competence is critical for medical graduates, yet in India the treatment gap for common mental disorders remains substantial, with prevalence estimates indicating up to 80.4% of unmet need. Recent reforms under the Competency-based Medical Education (CBME) curriculum have expanded psychiatry training; however, deficiencies in applied skills, preventive psychiatry, and communication remain. Psychiatry clubs have been proposed as supplementary, student-led platforms to address these limitations. This cross-sectional study assessed the perceived need for psychiatry clubs among undergraduate medical students and explored their potential role in enhancing teaching–learning. A structured online survey was administered to 94 students across different phases …


Localized Reticulate Hyperpigmentation From Heater Use: A Case Of Erythema Ab Igne, Chitwan Kaur Ghuman, Monish Yarlagadda, Ashwini P K Jan 2025

Localized Reticulate Hyperpigmentation From Heater Use: A Case Of Erythema Ab Igne, Chitwan Kaur Ghuman, Monish Yarlagadda, Ashwini P K

Digital Journal of Clinical Medicine

Background: Erythema ab igne (EAI) is a reticulated, hyperpigmented dermatosis resulting from prolonged exposure to infrared radiation insufficient to cause burns. While increasingly rare due to central heating, it remains relevant in vulnerable populations, particularly the elderly and immobilized.

Case Summary: We report the case of an 83-year-old bedbound female who developed characteristic pigmentary changes over her right upper and lower limbs due to chronic proximity to a room heater.

Conclusion: Awareness of EAI is crucial to prevent unnecessary investigations and to emphasize the importance of appropriate thermal environment modifications, especially in bedbound geriatric patients.


Extracapsular Excision Of Retroperitoneal Ancient Schwannoma: A Case Report, Mayur Chaure, Shital Dharamkhele, Keval Dhone, Imran Ahmed Khan Jan 2025

Extracapsular Excision Of Retroperitoneal Ancient Schwannoma: A Case Report, Mayur Chaure, Shital Dharamkhele, Keval Dhone, Imran Ahmed Khan

Digital Journal of Clinical Medicine

Schwannomas are tumors originating from Schwann cells in the nerve sheath. They are generally solitary and encapsulated, but they are rarely seen in the retroperitoneal region. We report a 40-years-old woman with dull aching pain for two months without urinary symptoms. Following imaging studies, a well-encapsulated, retroperitoneal mass complicated with intratumoral bleed and necrosis was found.

Complete surgical resection was performed with preservation of adjacent viscera. The histopathology report confirmed the tumor as an ancient schwannoma. Careful preoperative surgical planning and meticulous surgical skill, along with the application of ERAS protocol, are essential to prevent morbidity and mortality. No evidence …


Prevalence Of Depression Among Type 2 Diabetes Mellitus Patients In Urban Mysuru – A Cross-Sectional Study, Jesymol Joy, Renuka M, Chiranjeevi G S Jan 2025

Prevalence Of Depression Among Type 2 Diabetes Mellitus Patients In Urban Mysuru – A Cross-Sectional Study, Jesymol Joy, Renuka M, Chiranjeevi G S

Digital Journal of Clinical Medicine

Background: Depression is a significant comorbidity among individuals with Type 2 Diabetes Mellitus (T2DM) adversely affecting disease management and overall quality of life. Diabetes and depression have a bidirectional relationship, where poorly managed diabetes increases the risk of depression, and depression exacerbates diabetes-related complications. Depression contributes to poor glycemic control, decreased adherence to treatment, increased risk of diabetes-related complications, and higher healthcare utilization.

Objectives: To determine the prevalence of depression and its associated factors among Type 2 Diabetes Mellitus patients in urban Mysuru.

Methods: A community-based cross-sectional study was conducted among 300 Type 2 Diabetes mellitus patients >18 years of …


Allergic Bronchopulmonary Aspergillosis In Pediatric Asthma : A Diagnostic Challenge Mimicking Tuberculosis, Praveen Das, Santosh Kondekar, Surbhi Rathi Jan 2025

Allergic Bronchopulmonary Aspergillosis In Pediatric Asthma : A Diagnostic Challenge Mimicking Tuberculosis, Praveen Das, Santosh Kondekar, Surbhi Rathi

Digital Journal of Clinical Medicine

Allergic bronchopulmonary aspergillosis (ABPA) is a rare hypersensitivity reaction to Aspergillus fumigatus, more commonly observed in adults and patients with cystic fibrosis. It can, however, present in pediatric asthmatics with refractory symptoms, leading to diagnostic challenges due to overlapping features with other pulmonary diseases, including tuberculosis. ABPA should be considered in children with uncontrolled asthma and atypical radiologic features, especially when unresponsive to standard therapies. Early recognition and appropriate management are critical to prevent irreversible lung damage and improve quality of life.


Pregnancy-Related Delusional Beliefs In Midlife And Late-Life Women: A Case Series, Dyuksha Arora, Ashita Adarsh, Kishor M. Manohar Rao, Anand R, Soumya Rajshekar Patil, Akshatha Cj Jan 2025

Pregnancy-Related Delusional Beliefs In Midlife And Late-Life Women: A Case Series, Dyuksha Arora, Ashita Adarsh, Kishor M. Manohar Rao, Anand R, Soumya Rajshekar Patil, Akshatha Cj

Digital Journal of Clinical Medicine

Pseudocyesis and delusional pregnancy represent rare but clinically significant presentations across psychiatric practice. While pseudocyesis involves a false belief of pregnancy accompanied by physical manifestations, delusion of pregnancy refers to a fixed belief of being pregnant despite clear contrary evidence. Both conditions pose considerable challenges as they involve close consultation and liaison between Obstetrics & Gynaecology and Psychiatry. There are a few studies from tertiary care general hospitals in India. Here we report two case series.

Case 1: A 43-year-old married woman from a rural background with an 8-year history of recurrent depressive disorder and dysthymia, presented with 3 months …


One Airway, One Disease In Pregnancy: A Prospective Observational Study On The Correlation Between Upper And Lower Airway Inflammation In Pregnant Women, Durga K, Yuvarajan S Jan 2025

One Airway, One Disease In Pregnancy: A Prospective Observational Study On The Correlation Between Upper And Lower Airway Inflammation In Pregnant Women, Durga K, Yuvarajan S

Digital Journal of Clinical Medicine

Background: The well-established "One Airway, One Disease" concept recognizes the deep physiological and pathological connections between conditions affecting both the upper and lower respiratory tracts, most notably allergic rhinitis and asthma. During pregnancy, a woman's body undergoes significant immunological, hormonal, and physiological changes, which can profoundly influence and modulate existing or emerging airway inflammation.

Objective: This prospective observational study was designed with the primary objective of meticulously evaluating the correlation between upper and lower airway inflammation in pregnant women. We aimed to achieve this by assessing a range of clinical symptoms, objective functional parameters, and specific inflammatory markers.

Methods: We …


Comparision Of Buprenorphine Versus Butorphanol As An Adjuvant To Intrathecal Hyperbaric Bupivacaine For Elective Infraumbilical Surgeries : A Randomised Control Study At A Tertiary Care Hospital, Mandya, Surabhi C A, Dr. Kiran A V. Associate Professor, Dr. Shivakumar G Pofessor And Hod, Umesh N P Jan 2025

Comparision Of Buprenorphine Versus Butorphanol As An Adjuvant To Intrathecal Hyperbaric Bupivacaine For Elective Infraumbilical Surgeries : A Randomised Control Study At A Tertiary Care Hospital, Mandya, Surabhi C A, Dr. Kiran A V. Associate Professor, Dr. Shivakumar G Pofessor And Hod, Umesh N P

Digital Journal of Clinical Medicine

Introduction: Spinal anaesthesia is the most popularly performed procedure in the field of anaesthesiology. Hyperbaric bupivacaine, the local anaesthetic most commonly used, has limitation as its effect lasts only for 1.5-2 hours. Hence a lot of adjuvants have been tried to enhance the analgesic effect of bupivacaine.[2] Opioids remain the mainstay among the various adjuvants to local anesthetics in spinal anaesthesia primarily by virtue of its various properties such as reducing the dose of local anaesthetic, minimizing side effects, and prolonging the duration of anaesthesia.[3]

Aim: This study aims to compare the sensory and motor characteristics …


Elementary School-Based Speech-Language Pathologists' Perspectives On The Management Of Pediatric Feeding And Swallowing Disorders, Kelsi L. Szakovits Jan 2025

Elementary School-Based Speech-Language Pathologists' Perspectives On The Management Of Pediatric Feeding And Swallowing Disorders, Kelsi L. Szakovits

Senior Honors Theses and Projects

Speech-language pathologists (SLPs) frequently serve autistic students in the school setting. Research reveals a correlation between autism, sensory processing, and pediatric feeding disorder (PFD). As a result, autistic students may have compromised nutritional health and safety, which stands to impact their ability to access the curriculum. PFD is under the scope of the school-based speech-language pathologist’s practice. However, data has shown a perceived lack of confidence and a limited number of support and resources in the educational setting for SLPs to carry out interventions. This qualitative study will seek to understand the perspectives of elementary school-based SLPs regarding the implementation …


Relationship Between Ehealth Literacy And Use Of Patient Portals Among Older Adults: An Integrative Review, Lore Oluwatominiyi Jan 2025

Relationship Between Ehealth Literacy And Use Of Patient Portals Among Older Adults: An Integrative Review, Lore Oluwatominiyi

Senior Honors Theses and Projects

The rapid advancement of healthcare technologies, including patient portals, has the potential to improve patient engagement and health outcomes, particularly among older adults. However, the adoption of patient portals among this demographic remains relatively low, primarily due to varying levels of eHealth literacy. The aim of this integrative review, guided by the Whittemore and Knafl’s (2005) framework, was to investigate the experience of eHealth literacy and patient portal use among older adults. The databases of PubMed, CINAHL, and PsycINFO were searched for articles published between 2017 and 2023. Keywords used included: eHealth literacy, patient portals, and older adults. Thirty records …


Enhancing Nursing Education To Improve Care For Patients With Substance Use Disorder: A Literature Review, Allma Swier Jan 2025

Enhancing Nursing Education To Improve Care For Patients With Substance Use Disorder: A Literature Review, Allma Swier

Senior Honors Theses and Projects

Background. As nursing students attend undergraduate school and prepare to enter the workforce, clinical experience and classroom training shape who they will become as caregivers. There is a lack of education built into the standard curriculum on how to care for people with substance use disorders empathetically and professionally. Aim. The purpose of this literature review is to determine if nursing students feel adequately prepared to care for patients with substance use disorder, and how implementation of educational curricula can increase students' knowledge of caring for individuals with substance use disorder, leading to an increase in confidence when caring for …


Spinal Anesthesia For Cesarean Delivery In A Patient With A Ventriculoperitoneal Shunt: A Case Report, Michael Dearman, Jorden Gary, Evan Pivalizza Jan 2025

Spinal Anesthesia For Cesarean Delivery In A Patient With A Ventriculoperitoneal Shunt: A Case Report, Michael Dearman, Jorden Gary, Evan Pivalizza

School of Medicine Student Publications and Presentations

No abstract provided.


The Future Of Ai Regulation In Drug Development: A Comparative Analysis, Gabriela Lenarczyk, Timo Minssen, Nicholson Price, Arti Rai Jan 2025

The Future Of Ai Regulation In Drug Development: A Comparative Analysis, Gabriela Lenarczyk, Timo Minssen, Nicholson Price, Arti Rai

Faculty Scholarship

As artificial intelligence (AI) transforms drug development, regulatory frameworks are evolving to oversee its implementation, particularly at the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA). This paper makes three contributions to understanding emerging regulatory approaches. First, we offer a comparative analysis of how these agencies have responded to AI-driven advances, incorporating new US executive orders and the European Union (EU)’s AI Act. Second, we propose a novel analytical framework to understand regulatory divergence: the FDA’s flexible, dialog-driven model contrasts with the EMA’s structured, risk-tiered approach, reflecting broader institutional and political-economic differences. While the former encourages …


Maternal Mortality According To State Abortion Legislative Climate Following The Us Supreme Court's Dobbs V. Jackson Women's Health Organization Ruling, Emily Nuss, Mari Iwasaki, Lindsay Robbins, Peggy Ye, Misa Hayasaka, George Saade, Tetsuya Kawakita Jan 2025

Maternal Mortality According To State Abortion Legislative Climate Following The Us Supreme Court's Dobbs V. Jackson Women's Health Organization Ruling, Emily Nuss, Mari Iwasaki, Lindsay Robbins, Peggy Ye, Misa Hayasaka, George Saade, Tetsuya Kawakita

Department of Obstetrics & Gynecology Faculty Publications

Objective

We aimed to evaluate how maternal mortality rates have evolved across US states following the Dobbs ruling, while accounting for the confounding influence of the coronavirus disease 2019 (COVID-19) pandemic.

Study Design

We conducted a retrospective analysis of publicly available data from the Centers for Disease Control and Prevention Wide-ranging ONline Data for Epidemiologic Research (CDC WONDER) database from January 2018 to December 2024. This study period was divided into three intervals: (1) pre-COVID (January 2018 to February 2020), (2) pandemic (March 2020 to September 2022), and (3) post-Dobbs (October 2022 to December 2024). Using the Kaiser Family Foundation …


Methodological And Clinical Concerns In The Study On Postpartum Hypertension Management, Takaki Tanamoto, Kyosuke Kamijo, Yusuke Tsutsumi, Tetsuya Kawakita Jan 2025

Methodological And Clinical Concerns In The Study On Postpartum Hypertension Management, Takaki Tanamoto, Kyosuke Kamijo, Yusuke Tsutsumi, Tetsuya Kawakita

Department of Obstetrics & Gynecology Faculty Publications

[Introduction] We read with interest the recent study by Rosenfeld et al.¹ However, we have several clinical and methodological concerns about this study.¹

First, this study's propensity score matching (PSM) lacked key clinical confounders, including perinatal risk factors and the highest systolic/diastolic blood pressures. Smoking, alcohol use, and multifetal gestation, which influence blood pressure during pregnancy,²,³ potentially affect both primary and secondary outcomes. Additionally, the authors did not report standardized mean differences before and after PSM, which are essential for assessing balance.⁴


Diagnosis Of Hypertensive Disorders In Pregnancy, Rebecca Horgan, Yara Hage Diab, Maged Costantine, George Saade, Baha Sibai Jan 2025

Diagnosis Of Hypertensive Disorders In Pregnancy, Rebecca Horgan, Yara Hage Diab, Maged Costantine, George Saade, Baha Sibai

Department of Obstetrics & Gynecology Faculty Publications

Hypertensive disorders of pregnancy, including chronic hypertension, superimposed preeclampsia, gestational hypertension, and preeclampsia, affect 10-20% of pregnancies and are a significant cause of maternal and perinatal mortality. The incidence of these disorders is rising due to factors such as advanced maternal age, obesity, assisted reproductive technology, and increased rates of preexisting comorbidities. Differentiating pregnancy-associated hypertension from pre-existing chronic hypertension is challenging, as the overlap between the two may be broadening due to the changing demographics of the pregnant population. This review critically evaluated the evidence regarding the current time periods recommended to make a diagnosis of a hypertensive disorder of …


A Rare Case Of Non-Traumatic Rhabdomyolysis And Acute Kidney Injury Following Influenza A Infection, Josefina Barrera, Michael Dearman, Vincent Hoang, John Givler Jan 2025

A Rare Case Of Non-Traumatic Rhabdomyolysis And Acute Kidney Injury Following Influenza A Infection, Josefina Barrera, Michael Dearman, Vincent Hoang, John Givler

School of Medicine Student Publications and Presentations

Introduction: Influenza-induced rhabdomyolysis is a recognized but rare complication of influenza A infection. During the 2009 H1N1 pandemic, several cases of rhabdomyolysis associated with influenza were reported, highlighting the potential for severe extrapulmonary manifestations of the virus.

Case: A 24-year-old African American male with no significant medical history initially presented to a freestanding emergency room with fevers, chills, congestion, and body aches. Subsequently, he tested positive for influenza A and prescribed benzonatate, methocarbamol and promethazine. He returned four days later with persistent severe myalgias and dark urine consistent with rhabdomyolysis and evidenced by a creatine kinase level exceeding 20,000 U/L …


Identifying Doxorubicin-Induced Cardiotoxicity Using 4d Echocardiography, Bea O. Cabot, Cortland Johns, Benjamin Zeidler, Anna Webb, Wilhelm Smith, Aasish Karuturi, Craig J. Goergen Jan 2025

Identifying Doxorubicin-Induced Cardiotoxicity Using 4d Echocardiography, Bea O. Cabot, Cortland Johns, Benjamin Zeidler, Anna Webb, Wilhelm Smith, Aasish Karuturi, Craig J. Goergen

Discovery Undergraduate Interdisciplinary Research Internship

Doxorubicin is an effective, commonly used chemotherapeutic drug. However, this drug is accompanied with disadvantages. Specifically, doxorubicin is associated with cardiotoxicity, characterized by left ventricle dysfunction. We hypothesize that 4D ultrasound imaging can reveal cardiac changes associated with doxorubicin-induced cardiotoxicity earlier in disease progression than 2D ultrasound imaging. To test this hypothesis, C57BL/6J mice were separated into treatment or control groups. Intraperitoneal injections were administered weekly for 4 weeks, each dosage equivalent to 4 mg/kg of either doxorubicin (treated) or saline (control). A Vevo3100 high frequency ultrasound system (FUJIFILM VisualSonics) was used to collect 2D and 4D ultrasound images of …