Medicine and Health Sciences Commons^™

Differentially Expressed Mirnas Explain Racial Differences In Diagnosis Stage Among Triple Negative Breast Cancer Patients In Louisiana, Yawen Hu, Xioacheng Wu, Meng Luo, Nubaira Rizvi, Amjila Bam, Luis Del Valle, Lucio Miele, Qingzhao Yu

Journal of the Louisiana Public Health Association

Background: Triple-negative breast cancer (TNBC) is a highly aggressive subtype that disproportionately affects African American (AA) women, leading to worse survival rates and higher metastasis risks compared to Caucasian American (CA) women. MicroRNAs (miRNAs) are crucial in cancer development and hold promise as biomarkers, but their role in racial disparities in TNBC outcomes is unclear. Methods: This study used Louisiana Tumor Registry data and collected tumor tissues for miRNA sequencing to examine significant miRNAs differentially expressed by race and TNBC stages at diagnosis among 3,298 TNBC cases diagnosed from 2011 to 2017. Results: Of the TNBC cases, 49.7% were AA. …

Association Between Food Insecurity And Nervous System Disorders In Caddo Parish, La: A Call To Action For Health, Megan Gremillion, Morgan Uebinger, Claire Crosby, Kaitlyn Tholen, Marie Vazquez Morgan, Ammar Husan

Journal of the Louisiana Public Health Association

Background: Food insecurity (FI)–the lack of access to affordable, nutritious food–affects millions of Americans. Caddo Parish, Louisiana, is of interest due to high FI prevalence and socioeconomic risk factors. While FI is known to exacerbate chronic health issues, its association with neurological health remains understudied, especially in high-risk communities. Methods: A cross-sectional study was conducted among adult patients in Caddo Parish in 2022 using Epic Electronic Medical Record data to identify diagnoses of migraine, dementia, and stroke—the top neurological causes of disability-adjusted life years (DALYs) in the United States. FI status was determined using the Hunger Vital Sign screening questionnaire. …

Volume 5 November '25 Cover, Publishing, And Table Of Contents, Donna Wlliams

Journal of the Louisiana Public Health Association

No abstract provided.

Pediatric Firearm Injuries In A Major Urban Louisiana City: A Deadly Public Health Issue, Morgan Brown, Jenny Stevens, Jose Cruz Ayala, Claudia Leonardi, Alison Smith, Fabienne Gray

Journal of the Louisiana Public Health Association

Background: In 2019, firearm injuries surpassed motor vehicle collisions as the leading cause of pediatric death in the US. In Louisiana, firearm injuries represent the leading cause of pediatric death since 2013. A more comprehensive understanding of risk factors associated with pediatric firearm injury is needed to improve outcomes. Methods: A retrospective review from 2016-2023 of pediatric trauma patients presenting to a Level I Adult Trauma Center & Level II Pediatric Trauma Center in a major urban Louisiana city was performed. Demographics, mechanism of injury, and injury intent were evaluated. Results: Among 8,832 patients, 1,116 (12.6%) sustained firearm injuries. Among …

High Activity Urban Event Impacts Local Air Quality Of The Claiborne Corridor In New Orleans, La, Evrim Oral, Daniel Harrington, Mohamed S. Mohamed, Mohamed S. Rahman, Saheba Cuccia, Samrat Mukherjee, Amy Stelly, Barry Keim, Adrienne Katner

Journal of the Louisiana Public Health Association

Background: This paper presents fine particulate matter air pollution measurements in the hours before, during, and after a Port of New Orleans labor strike and a multi-day concert held at the New Orleans Superdome. Both events occurred in areas adjacent to the Claiborne Expressway, an elevated highway extension of Interstate-10 (I-10), which runs through the Claiborne Corridor neighborhood of the City of New Orleans, LA (USA). Methods: Air sensors were located southeast and northwest of the Claiborne Expressway to measure respirable “fine particulate matter” (PM2.5), a traffic-related pollutant associated with cardiovascular and respiratory disease. Ambient PM2.5 concentration measurements were collected …

Characterizing Global Dermatologic Engagement And Needs: A Cross-Sectional Study From 83 Countries, Alexis G. Strahan, Christine Li, Maud Guérin, Tom Allison, Gene Colón, Jehireh Peraza-Williams, Olyvia Zarchin, Morvarid Zehtab, Ann M. Pacheco, Jadesola Akinwuntan, Shivani Jain, Marlous L. Grijsen, Wendemagegn Enbiale, Wingfield Rehmus, L. Claire Fuller, Karolyn Wanat, Esther E. Freeman

School of Medicine Faculty Publications

No abstract provided.

The Associations Between Meniscus Tear Location And The Prevalence And Severity Of Cartilage Wear In Different Knee Compartments Using An Arthroscopic Grading System, Tara Korbal, Claudia Leonardi, Amy Bronstone, Vinod Dasa

School of Medicine Faculty Publications

Introduction: Meniscus tears are associated with progressive cartilage degeneration and worsening osteoarthritis. Although several previous studies have explored the relationship between meniscus tears and cartilage damage, few have examined the relationship between tear location and cartilage wear in all knee compartments using an arthroscopic grading system. Objectives: Evaluate the association between meniscus tear location and the prevalence and severity of high-grade cartilage wear in knee compartments. Methods: A total of 210 patients were categorized into groups based on meniscus tear location: medial meniscus tear (MMT, n = 106), lateral meniscus tear (LMT, n = 41), and medial-lateral meniscus tear (MLMT, …

Development Of Evidence-Based Clinical Practice Guidelines For Monitoring Diabetic Patients Using Smartphone Technology, Ganiyat Funmilayo Efuntoye

Walden Dissertations and Doctoral Studies

In this doctoral project, I developed and validated an evidence-based clinical practice guideline for implementing smartphone technology to monitor diabetic patients in primary care settings with an 80% threshold. The project addressed a critical gap in standardized guidance for diabetes technology integration, which has resulted in inconsistent adoption and suboptimal patient outcomes. A systematic literature review of four major databases yielded 12 high-quality studies representing all evidence levels (I–V) according to the Johns Hopkins evidence-based practice model. Evidence synthesis revealed strong and compelling evidence with consistent results supporting smartphone technology implementation, including HbA1c improvements of 0.4%–0.8%, sustained patient engagement rates …

Epidemiology Of Metabolic Syndrome In Patients With Inflammatory Bowel Disease: A Population-Level Cohort Study From The United States, Aakash Desai, Himsikhar Khataniar, Jana G. Hashash, Priya Sehgal, Francis A. Farraye, Gursimran S. Kochhar

Division of Gastroenterology and Hepatology Faculty Papers

BACKGROUND: Epidemiological data on metabolic syndrome (MetS) in patients with inflammatory bowel disease (IBD) are limited.

METHODS: A retrospective cohort study was conducted using the United States (US) Collaborative Network (TriNetX) to obtain data for patients with IBD between 2010 and 2023. The primary aim of the study was to estimate the prevalence of MetS in ulcerative colitis (UC) and Crohn's disease (CD). Prevalence was further characterized by age, sex, race, disease location, IBD medications, history of surgery, and IBD phenotype.

RESULTS: Among 100,890 patients with IBD, metabolic syndrome (MetS) affected 34.4% overall (UC 32.4%, CD 34.3%). Prevalence rose sharply …

Streamlining Sepsis Care And Enhancing Antibiotic Administration Efficiency Through Emergency Department Staff Nurse Education, Dafina Jamillah Skinner

Walden Dissertations and Doctoral Studies

Sepsis is a life-threatening medical emergency that requires rapid identification and treatment. Delays in administering antibiotics are directly associated with increased mortality, longer hospital stays, and higher complication rates. Without intervention, patients faced preventable harm, and the organization risked continued non-compliance with federal quality measures. This Doctor of Nursing Practice (DNP) project implemented a structured educational program for emergency department (ED) nurses to improve knowledge of evidence-based sepsis protocols. The practice-focused question asked: For nurses in the ED, will an educational intervention on sepsis recognition and antibiotic stewardship improve knowledge of timely antibiotic administration and blood culture acquisition? Twenty ED …

Nursing Faculty Demographics, Attitude, Knowledge, And Integration Of Complementary And Alternative Medicine In Nursing Curriculum, Patricia L. Balistreri

Walden Dissertations and Doctoral Studies

Nurses have demonstrated positive attitudes toward complementary and alternative medicine (CAM); however, additional education is limited in nursing programs to prepare them to discuss and educate patients about these practices. Nursing faculty play a significant role in educating, mentoring, and influencing students’ knowledge levels and attitudes toward CAM. The purpose of this quantitative, non-experimental, cross-sectional study, guided by the CAM healthcare model, was to examine relationships among nursing faculty demographics, CAM knowledge, attitudes, and curriculum integration. The Knowledge, Attitudes, and Use of CAM survey was administered to 111 nursing faculty across multiple programs. Data were analyzed using multiple linear regression …

Identifying Compounds To Treat Opiate Use Disorder By Leveraging Multi-Omic Data Integration And Multiple Drug Repurposing Databases, Jeran K Stratford, Megan Ulmer Carnes, Caryn Willis, Melyssa S Minto, Logain Elnimeiry, Ravi Mathur, Matthew Schu, Bryan C Quach, Javan Carter, Tracy Nolen, Nathan Vandergrift, Thomas R Kosten, Eric Otto Johnson, Bradley T Webb

Faculty, Staff and Students Publications

Genes influencing opioid use disorder (OUD) biology have been identified via genome-wide association studies (GWAS), gene expression, and network analyses. These discoveries provide opportunities to identifying existing compounds targeting these genes for drug repurposing studies. However, systematically integrating discovery results and identifying relevant available pharmacotherapies for OUD repurposing studies is challenging. To address this, we've constructed a framework that uses existing results and drug databases to identify candidate pharmacotherapies. For this study, two independent OUD related meta-analyses were used including a GWAS and a differential gene expression (DGE) study of post-mortem human brain. Protein-Protein Interaction (PPI) sub-networks enriched for GWAS …

Perception Of Emotion In Autism With Controlled Elicitation (Peace), Austin Gillespie, Rachel E. Dewald

Undergraduate Research Symposium Lightning Talks

It is possible that autistic people find it easier to socialize within their own peer group (Beaupré & Hess, 2006), by recognizing socio-emotional nonverbal cues, due to a shared neurodivergence. To assess this, it would be helpful for researchers to have a database of emotional stimuli, validated for use with autistic individuals. Unfortunately, this does not exist. This current study’s objective is to create such a database that evokes natural emotion, rated by autistic individuals to be used in future research. All participants completed the Alexithymia Scale (TAS-20) which measures the participants’ ability to identify and describe their own emotions …

The Emotional Climate Crisis: An Integrative Review Of Mental Health Outcomes From Climate-Related Disasters, Vidhani Goel, Roberto Sagaribay

Undergraduate Research Symposium Lightning Talks

Introduction: Climate change is a planetary and public health crisis. Between 2000 and 2019, over 1.2 million deaths and 4 billion individuals were affected by climate-related disasters. These events often impact mental health. This integrative review synthesizes evidence on mental health outcomes particularly post-traumatic stress disorder (PTSD), anxiety, and eco-anxiety among populations affected by climate disasters. Methods: Using Whittemore and Knafl’s five-stage framework, this integrative review is in the preliminary analysis stage. A systematic search will be conducted for peer-reviewed studies published globally from January 1995 to March 2024. Eligible studies include quantitative, qualitative, and mixed-methods research on mental health …

Inflammaging And Cognitive Decline: A Brief Review Of The Chronic Low-Grade Neural Inflammation Hypothesis, Gage Pompa

Undergraduate Research Symposium Lightning Talks

This presentation reviews the chronic low‑grade neural inflammation hypothesis as a mechanism linking aging to cognitive decline. Inflammaging refers to persistent, low‑level inflammation that develops with age due to immune dysregulation in the absence of infection. In the brain, this process is often triggered by the accumulation of beta‑amyloid plaques and phosphorylated tau tangles. Microglia attempt to clear these proteins, but their prolonged activation releases inflammatory mediators that damage surrounding neurons. Over time, this sustained neural inflammation contributes to neurodegenerative conditions such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, epilepsy, and psychiatric disorders including schizophrenia and major depression. Imaging markers …

Examining County-Level Barriers To Midwife-Attended Births Among Black Women In The United States, Asia Miles

Undergraduate Research Symposium Posters

Background and Objectives: In 2011, the American Public Health Association (APHA) passed legislation aimed at reducing maternal mortality and morbidity by addressing shortages in maternity care providers and facilities. The purpose of this study was to examine county-level characteristics that influence Black women’s access to midwife-attended births across the U.S. Methods and Approach: Data on midwife-attended births were obtained from CDC WONDER for U.S. counties with populations of 100,000 or greater, and county-level characteristics were gathered from the Area Health Resources File. The dependent variable was the change in nurse-midwife-attended births from 2011 to 2023. Independent variables included changes in …

Feasibility And Preliminary Efficacy Of Uneven Terrain Gait Training In Lower Limb Prosthesis Users, Gabriel Bacani, Dawn Ruby, Sara Hazen, Katie Bricarell

Undergraduate Research Symposium Posters

Lower limb prosthesis users (LLPUs) often feel less confident walking in their day-to-day lives. Even with rehabilitation, some individuals do not develop the skills and confidence needed to walk across different terrains. Walking practice on varied terrains may be a method for increasing skill and confidence. The purpose of this study is to assess the feasibility of implementing an uneven terrain training program for LLPUs. Three LLPUs completed a series of 12 training sessions on an uneven terrain treadmill. Participants walked for up to 12 trials per session with each bout lasting up to 2 minutes. The terrain increased in …

Supplement Use And Ed Self-Assessment Accuracy, Darin Beasley-Williams

Undergraduate Research Symposium Posters

The widespread availability of dietary supplements has contributed to their increased use, with over half of U.S. adults reporting regular consumption. Prior research suggests that supplement use is associated with better overall health, and regulatory legislation has been implemented to mitigate potential adverse effects. One motivation for supplement use may be self-diagnosed health issues; however, incorrect self-diagnoses could lead to inappropriate supplement consumption and potentially contribute to disordered eating patterns. This study examined whether regular supplement users are more accurate in self-identifying an eating disorder. A sample of 511 undergraduate students completed a self-report questionnaire assessing supplement use and eating …

Women’S Lived Experiences With Harassment In Gaming, Angelo Cordero, Alejandra Santos, Claudia Q. Luu

Undergraduate Research Symposium Posters

Background and objectives: Women in gaming communities face discrimination due to their gender; however, gaps exist in the literature in understanding how allyship helps mitigate harassment’s harmful effects. To address this, we conducted a qualitative study exploring women’s lived experiences of sexual harassment in gaming and how women perceive allyship in gaming communities. Methods and approach: We used an inductive thematic analysis to identify patterns in participants’ experiences. Our sample (N = 165) included adult women who identified as gamers, recruited from a university and various Discord gaming communities. Results: We uncovered six main themes regarding women’s harassment experiences in …

Capacity, Allocation And Update Dynamics Of Human Memory Systems, Shaoying Wang

Electronic Theses and Dissertations

Information is encoded and stored in three types of memory: sensory memory (SM), short-term memory (STM), and long-term memory (LTM). SM has a large capacity but retains information for only a brief period. When information transfers to STM, only a limited amount can be stored. Information in STM can then be transferred to LTM, which has a much larger capacity and longer retention time. STM is often conceptualized as working memory (WM) to highlight its role in active information processing. Due to the limited capacity of STM, it is commonly believed that STM serves as the bottleneck for information processing. …

Understanding The U.S. Maternal Healthcare System At The Intersection Of Asian American Birth Outcomes And The Model Minority Stereotype: A Literature Review, Sophia Hevel

University Honors Theses

This thesis aims to explore the maternal healthcare system in the United States as it pertains to Asian American birthing people, the ways in which their racial, ethnic, and cultural identities are interacted with within the U.S. Healthcare system, and subsequently the detrimental effects of the medical system's devaluation of culturally specific birthing and postpartum practices have on Asian American birthing experiences. This will be accomplished through an exploration of the United States' maternal healthcare system, or rather, its crisis; how Asian Americans navigate a system that has not been structured to support their specific needs; and lastly, a discussion …

The Time-Dependent Association Between Irritable Bowel Syndrome And All-Cause And Cause-Specific Mortality In The Nih-Aarp Cohort Study, Daniela S Gutiérrez-Torres, Fangyu Li, Linda M Liao, Carrie R Daniel, Shreela V Sharma, Ruosha Li, Eric L Brown, Qing Lan, Maki Inoue-Choi, Baharak Moshiree, Paul Albert, Rashmi Sinha, Emily Vogtmann

Faculty, Staff and Student Publications

Introduction: Evidence on the association between irritable bowel syndrome (IBS) and mortality is conflicting. In this study, we estimated the association between IBS and all-cause and cause-specific mortality in the NIH-AARP Diet and Health Study.

Methods: IBS diagnoses between 1994 and 2008 were identified from Medicare claims data, and mortality outcomes through 2019 were obtained through linkage to the National Death Index. Using multivariable Cox proportional hazards regression models, we estimated hazard ratios (HRs) and 95% confidence intervals (CIs) for all-cause and cause-specific mortality within partitioned follow-up time categories (>2-5, >5-8, >8-11, >11-14, >14-17, and >17 years) with adjustment …

Risk Factors For Unexpected Death In Patients Identified By A Communication And Resolution Program, Peter Lodato, Neal D. Goldstein, Alexandra M, Mapp, Adebayo Gbadebo, David A. Paul

Department of Pediatrics Faculty Papers

Many patients experience unexpected harm while receiving healthcare, with a lasting impact on patients, families, and caregivers. Communication and Resolution Programs are being adopted with increased frequency, as a more systematic, transparent, and equitable approach to these unexpected outcomes. The aim of this study was to identify whether demographic factors played a role in identifying patients with unexpected death, as managed in our CRP. This nested case-controlled compared 236 patients who experienced an unanticipated death with 2,360 controls who died expectedly over a 10-year period. Patients with unexpected death were more likely to be Black (AOR 2.18 95% CI 1.01-4.68), …

Norms For Scaling Up Small And Sick Newborn Care: An Overview Of Reviews, Natalie A. Strobel, Georgia Whisson, Derek Swe, Amy Budrikis, Karen M. Edmond

Research outputs 2022 to 2026

Background: The World Health Organization (WHO) and the United Nations Children's Fund (UNICEF) currently have no benchmarks or 'norms' for scaling up small and sick newborn (SSN) service delivery in health facilities in low- and middle-income countries (LMICs). Our objective was to understand which systematic reviews had addressed the following norms in the last five years: number of SSN beds per live births in a district or similar administrative unit (admission beds); space requirements for SSN units, including mother-infant dyads (space); health workforce ratios in SSN units (workforce); and travel time to health facilities with SSN units (travel time). Methods: …

Liver-Directed Base Editing Of Abcc6 Prevents Ectopic Calcification In A Variant-Humanized Mouse Model Of Pseudoxanthoma Elasticum, Lauren C. Testa, Dora Obiri-Yeboah, Hooda Said, Ping Qu, Michael A. Levine, Mohamad-Gabriel Alameh, Kiran Musunuru, Qiaoli Li, Xiao Wang

Department of Biochemistry and Molecular Biology Faculty Papers

Pseudoxanthoma elasticum (PXE) is an autosomal recessive connective tissue disorder characterized by ectopic calcification of elastic fibers throughout the skin, retina, and arteries. It is caused by pathogenic variants in ABCC6 , which encodes a transmembrane transporter that primarily localizes to hepatocytes. Loss of ABCC6 function in hepatocytes leads to systemic deficiency of inorganic pyrophosphate (PPi), a potent inhibitor of calcification; such depletion of PPi from the circulation is responsible for multisystemic ectopic calcification seen in PXE. Therefore, liver-targeted variant correction by genome editing and subsequent restoration of systemic PPi may offer a one-and-done therapeutic approach for PXE. The ABCC6 …

Impact Of Peek Implant Surface Design On Postoperative Complications In Cranioplasty: A Retrospective Review, Carmen A Zavala, Laura Zima, Subhiksha Srinivasan, Sanjay V Neerukonda, Mark J Dannenbaum

Faculty, Staff and Student Publications

Background: The aim of this study was to evaluate and compare complication rates and clinical outcomes associated with smooth and perforated polyetheretherketone (PEEK) implants used in cranioplasty.

Methods: A retrospective analysis of 94 patients who underwent cranioplasty with either smooth (n = 45) or perforated (n = 49) PEEK implants over a five-year period was conducted. Patient demographics, comorbidities, reasons for initial craniectomy, time interval between craniectomy and cranioplasty, postoperative complications, hospital stays, and rates of revision surgeries were analyzed. Multivariate logistic regression was used to control for confounding factors.

Results: No statistically significant differences were observed in demographic characteristics, …

Integrative Profiling Strategies To Guide Personalized Therapy In Mantle Cell Lymphoma: A Pilot Study, Yang Liu, Holly A Hill, Yijing Li, Joseph Mcintosh, Vivian Jiang, Fangfang Yan, Yixin Yao, Yue Fei, Jared Zhang, Lawrence Qu, Jun Yao, Preetesh Jain, Ken Chen, Michael Wang

Faculty, Staff and Student Publications

Mantle cell lymphoma (MCL) responds to frontline therapy but is susceptible to relapse. While Bruton's tyrosine kinase inhibitors (BTKi) achieve high response rates, most patients eventually experience disease progression. Predicting responses to subsequent treatments remains challenging due to the lack of an established platform. Heterogeneity in gene alterations and cellular pathways contribute to resistance, complicating treatment approaches. Here, we present a multi-modal profiling platform, targeting key pathways rather than focusing on singular DNA-associated lesions. We identified dysregulated signaling pathways by performing gene expression profiling on 20 MCL samples using a custom MCL MATCH gene set and analyzed the data with …

Diras3-Derived Cyclic Peptides Disrupt Kras-Raf Interaction And Kras Nanoclustering, Suppressing Kras-Driven Pancreatic And Ovarian Tumors, Joshua P Gray, Gamze Bildik, Ha-Neul Kim, Margie N Sutton, Jing Wang, Amarachi O Osuji, Nefeli Batistatou, Hailing Yang, Weiqun Mao, Zhi Tan, Geneviève M C Gasmi-Seabrook, Junchen Liu, John F Hancock, Christopher B Marshall, Joshua A Kritzer, Mitsuhiko Ikura, Robert C Bast, Steven W Millward, Zhen Lu

Faculty, Staff and Students Publications

Mutations in KRAS drive 88% of pancreatic ductal adenocarcinomas (PDAC) and up to 40% of low-grade serous ovarian cancers (LGSOC), making KRAS a long-standing therapeutic target. We previously showed that DIRAS3 binds RAS, forming heterodimers that disrupt RAS clustering and downstream MAPK signaling. Building on this, we developed conformationally constrained DIRAS3-derived peptides using two cyclization strategies and characterized them by NMR and biolayer interferometry. These cyclic peptides attenuate the interaction between KRAS and the BRAF RAS-binding domain, penetrate cells efficiently, and inhibit KRAS nanoclustering on the inner leaflet of the plasma membrane. Functionally, they reduce cell viability and suppress PDAC …

Shp2: A Redox-Sensitive Regulator Linking Immune Checkpoint Inhibitor Therapy To Cancer Treatment And Vascular Risk, Silvia Fernanda López Moreno, Stefania Assunto Lenz, Bernardo Casso-Chapa, Angelica Paniagua-Bojorges, Jung Hyun Kim, Nicolas L Palaskas, Kevin T Nead, Venkata S K Samanthapudi, Gilbert Mejia, Oanh Hoang, Jonghae Lee, Steven H Lin, Joerg Herrmann, Guangyu Wang, Syed Wamique Yusuf, Cezar A Iliescu, Noah I Beinart, Charlotte Manisty, Masuko Ushio-Fukai, Tohru Fukai, Pietro Ameri, Roza I Nurieva, Michelle A T Hildebrandt, Keri Schadler, Efstratios Koutroumpakis, Sivareddy Kotla, Nhat-Tu Le, Jun-Ichi Abe

Faculty, Staff and Student Publications

Src homology 2-domain containing protein tyrosine phosphatase 2 (SHP2), encoded by the Ptpn11 gene (Tyrosine-protein phosphatase non-receptor type 11), is a key downstream effector of PD-1/PD-L1 signaling and is likely important, in addition to immune modulation, in tumor development and vascular homeostasis. SHP2 conveys PD-1 mediated inhibitory signaling in T cells, and is emerging as a therapeutic target. Importantly, there is an association between immune checkpoint inhibitors (ICIs), immune-related adverse events (irAEs), and cardiovascular complications, underscoring the need to understand SHP2’s role in these processes. This review aims to summarize current knowledge on SHP2/PTPN11 biology, its role in immune …

A Cluster-Randomized Controlled Trial Assessing The Effectiveness Of A Multifaceted Versus A Discrete Implementation Strategy On Fidelity To An Occupational Guideline For The Prevention Of Mental Health Problems At The Workplace: A Dual Perspective From Swedish Schools, Andreas Rödlund, Anna Toropova, Rebecca Lengnick-Hall, Byron J Powell, Liselotte Schäfer Elinder, Christina Björklund, Lydia Kwak

2020-Current year OA Pubs

BACKGROUND: Although the management of psychosocial risks in the work environment represents an evidence-based approach to the prevention of mental health problems, its implementation is limited, including in schools, and knowledge on how to support better implementation is scarce. This study compares the effectiveness of a multifaceted vs. a discrete implementation strategy on fidelity to an occupational guideline for the prevention of mental health problems. Dual perspectives were used to assess fidelity, an important aspect of the measurement agenda.

METHODS:  A cluster-randomized controlled trial was conducted among 55 schools in Sweden. A multifaceted strategy (educational meeting, implementation teams, ongoing training, …