Medicine and Health Sciences Commons^™

The Essential Role Of Carbon Metabolism In The Virulence Of Cryptococcus Neoformans, Mara Weigner

Senior Honors Theses

Cryptococcus neoformans infections are a major cause of meningoencephalitis in immunosuppressed patients worldwide. Inhaled as spores or desiccated yeast cells, C. neoformans can undergo metabolic changes in response to the new host environment that allow it to cross the blood brain barrier and cause deadly central nervous system (CNS) infections. Nutrient acquisition, and specifically carbon metabolism, is critical for survival and proliferation within the host. Notably, efficient carbon metabolism is necessary to produce the polysaccharide capsule, which is arguably C. neoformans’ most important and well-studied virulence factor. As such, a better understanding of carbon acquisition and regulation is essential for …

Tracking Canada Geese Near Airports: Using Spatial Data To Better Inform Management, Ryan Askren, Brett E. Dorak, Heath M. Hagy, Michael W. Eichholz, Brian E. Washburn, Michael P. Ward

United States Department of Agriculture Wildlife Services: Staff Publications

The adaptation of birds to urban environments has created direct hazards to air transportation with the potential for catastrophic incidents. Bird–aircraft collisions involving Canada geese (Branta canadensis; goose) pose greater risks to aircraft than many bird species due to their size and flocking behavior. However, information on factors driving movements of geese near airports and within aircraft arrival/departure areas for application to management are limited. To address this need, we deployed 31 neck collar-mounted global positioning system transmitters on Canada geese near Midway International Airport in Chicago, Illinois, USA during November 2015 to February 2016. We used the movement data …

Ethical Standards For Cardiothoracic Surgeons' Participation In Social Media., Thomas K. Varghese, John W. Entwistle, John E. Mayer, Susan D. Moffatt-Bruce, Robert M. Sade

Department of Surgery Faculty Papers

No abstract provided.

Regional Variation In Chronic Kidney Disease And Associated Factors In Hypertensive Individuals In Rural South Asia: Findings From Control Of Blood Pressure And Risk Attenuation-Bangladesh, Pakistan And Sri Lanka, Liang Feng, Hithanadura Asita De Silva, Imtiaz Jehan, Anuradhani Kasturiratne, Gulshan Himani, Mohammad Abul Hasnat, Tazeen Jafar, Cobra-Bps Study Group

Community Health Sciences

Background: We aimed to determine the prevalence of chronic kidney disease (CKD) and its cross-country variation among hypertensive individuals in rural Bangladesh, Pakistan and Sri Lanka. We also explored the factors associated with CKD in these populations.
Method: We studied baseline data from the Control of Blood Pressure and Risk Attenuation-Bangladesh, Pakistan and Sri Lanka (COBRA-BPS) trial, an ongoing cluster randomized controlled trial on 2643 hypertensive adults ≥40 years of age from 30 randomly selected rural clusters, 10 in each of the three countries. CKD was defined as an estimated glomerular filtration rate (eGFR) /min/1.73 m2 or a urine albumin:creatinine …

Modal Sosial Bonding Dalam Pengembangan Kampung Wisatakreatif Dago Pojok Kota Bandung, Provinsi Jawa Barat, Alfrojems Alfrojems, Triyanti Anugrahin

Jurnal Ilmu Kesejahteraan Sosial

The development of a tourism village has become one of the primaries in community development, especially in rural areas, carried out either by the government or other parties. This is an effort to alleviate poverty in rural areas which is currently an area with a reasonably large amount of poverty with 15.15 million people. But the process of this development provides a dilemma and question about how the process can develop bondsin the community itself that are relevant to the context of bonding social capital. This article aims to explore information about how Dago Pojok creative tourism village community develops …

Hambatan Serikat Pekerja Dalam Penyelesaianpermasalahan Hubungan Industrial, Fitriyah Fitriyah, Rakha Gusti Wardhana

Jurnal Ilmu Kesejahteraan Sosial

Although labore unions can help their members in solving problems related to industrial relations, it still takes a long time due to the lack of it’s ability to negotiate with companies. This can be seen in the process of resolving layoffs and work status at PT X which took 4 years, from 2013 to 2016 to reach an agreement. This research aims to describe the obstacles faced by labor unions in conducting negotiations and the efforts they have made to improve their capabilities. This research is a qualitative descriptive study and using purposive sampling techniques to selected the informant and …

Hubungan Tingkat Work-Life Balance Terhadap Tingkatkepuasan Kerja Karyawan Organisasi Pelayanankemanusiaan, Karyawan Yayasan Plan Internationalindonesia, Iga Larasati, Ety Rahayu

Jurnal Ilmu Kesejahteraan Sosial

This undergraduate thesis discusses about the correlation of work-life balance to job satisfaction among Yayasan Plan International Indonesia’s Employees. This research is a quantitative research with descriptive design. This research is background by the importance of employee’s satisfaction in the Human Service Organization’s setting. Meanwhile, the research about employee’s job satisfaction among Human Service Organization is still rare. The result of this research shows that there’s a very weak correlation between the level work-life balance to the level of job satisfaction among Yayasan Plan International Indonesia’s Employees. This can be caused by the difference in characteristic between HSO and company. …

Strategi Bertahan Hidup Nelayan-Nelayan Kecil Desa Batu Ampar,Kecamatan Palmatak, Kabupaten Anambas, Lutfiana Nur Azizah, Triyanti Anugrahini

Jurnal Ilmu Kesejahteraan Sosial

Common problems faced by fishermen include the limited availability of fish resources, due to over fishing, climate change and the instability of fish selling prices. This condition is also experienced by small fishermen in Batu Ampar Village who carry out traditional fishing activities on the high seas. Facing the limitations of accessible fish resources and the uncertainty of the climate, they made various efforts so that they could survive. The purpose of this study was to describe the survival strategies of small fishermen in Batu Ampar Village in dealing with the problems faced while they were at sea. This research …

Penyandang Disabilitas Di Indonesia:Perkembangan Istilah Dan Definisi, Dini Widinarsih

Jurnal Ilmu Kesejahteraan Sosial

Riset menunjukkan keterkaitan erat antara pemahaman publik tentang disabilitas dan penyandang disabilitas dengan perilaku diskriminatif yang mereka alami dalam kehidupan sehari-hari. Pemahaman umum masyarakat di dunia, termasuk Indonesia, tentang penyandang disabilitas masih cenderung negatif. Pemahaman negatif itu karena masyarakat umumnya mendefinisikan dan memperlakukan penyandang disabilitas berdasarkan pada pola pikir yang didominasi oleh konsep kenormalan yang berimplikasi pada stigmatisasi dan diskriminasi terhadap para penyandang disabilitas. Hal itu, termasuk di Indonesia terutama disebabkan masih terbatasnya diseminasi informasi dan edukasi resmi dari pemerintahan atau otoritas terkait serta hasil kajian ilmiah tentang disabilitas dan penyandang disabilitas. Artikel ini bertujuan mendeskripsikan kajian literatur terkait pemahaman …

The 105th Anniversary Of King Chulalongkorn Memorial Hospital: Proud Of Our Past, Preparing For Our Future, Sittisak Honsawek

Chulalongkorn Medical Journal

No abstract provided.

Evaluation Of T2 Value For Detection Of Metastatic Cervical Lymph Node In Head And Neck Squamous Cell Carcinoma Compared With 18f-Fdg Pet/Ct, Netsiri Dumrongpisutikul, Vorada Sonthithavorn

Chulalongkorn Medical Journal

Background: Difference in the staging of head and neck cancer leads to different treatments and managementsof the patients to minimize mortality and improve long-term health and social consequences.Objective: This study aimed to utilize the T2 signal value on T2WI for early detection of metastatic lymph nodes.Methods: We retrospectively reviewed 18-fluoro-deoxyglucose positron emission tomography/computedtomography (18F-FDG PET/CT) and magnetic resonance imaging (MRI) results of patients with head and necksquamous cell carcinomas, from January 2012 to February 2018. The ratio between the T2 signal values of thelymph nodes and sternocleidomastoid muscles were calculated for each lymph node. Analytical comparisonsbetween T2 signal value ratios …

Impact Of Shift Work On Sleep Quality Among Nursing Staff, Patthrarawalai Sirinara, Nitt Hanprathet, Krit Pongpirul, Wiroj Jiamjarasrangsi

Chulalongkorn Medical Journal

Background: Shift work is common among nurses because health care is the industry that covers 24 hoursa day, 7 days a week. How a healthcare organization alters staffing patterns to reduce fatigue among nursing staffis challenging. This study aimed to understand whether poor sleep quality persisted in nursing staff who didshift work and whether there were any specific risk factors for poor sleep quality among nursing staff. The studyused a validated tool called the Pittsburgh Sleep Quality Index (PSQI) in Thai version for sleep quality assessment.Methods: This study was a cross-sectional study. Semi-structured questionnaires were used to interviewnursing staff who …

Exercise Training Improves Age-Related Changes In Cerebral Capillary Vascularity Through The Upregulation Of Pi3k / Akt Signaling, Channipa Chanpakdee, Sheepsumon Viboolvorakul, Suthiluk Patumraj

Chulalongkorn Medical Journal

Background: Currently, the number of the elderly has been rising sharply worldwide. Seemingly, age-inducedcerebral endothelial dysfunction may lead to vascular abnormality that can later progress to cerebrovascularand neurodegenerative diseases. Moreover, several evidences have shown that age-related oxidative stress anddecline in cellular function appeared in the vascular system both in humans and laboratory animals. The role ofexercise training in the regulation of age-related oxidative stress and endothelial functions have been reported.Objectives: To investigate whether exercise training can prevent age-induced cerebral endothelial dysfunctionassociated to PI3K/Akt signaling.Methods: Male Wistar rats were randomly divided into 3 groups: sedentary-young group (SE-Young, 4 months),sedentary-aged group (SE-Aged, …

Association Of Vitamin D-Related Genetic Variations And The Susceptibility Among Thai Children With Biliary Atresia, Kanjaporn Sirisomboonlarp, Natthaya Chuaypen, Sittisak Honsawek, Palittiya Sintusek, Voranush Chongsrisawat, Pisit Tangkijvanich

Chulalongkorn Medical Journal

Background: Vitamin D deficiency is commonly found in children with biliary atresia (BA). Single nucleotidepolymorphisms (SNPs) in vitamin D-related genes are linked to circulating vitamin D levels in various chronicliver diseases.Objective: This study aimed to investigate whether vitamin D related SNPs were associated with diseasesusceptibility and clinical manifestations in Thai children with BA.Methods: DNA specimens from 85 Thai children with BA and 90 age and gender matched healthy controlswere genotyped for DHCR7 rs12800438, CYP2R1 rs10741657 and GC rs7041 using TaqMan polymerase chainreactions.Results: The frequency of the T allele of GC rs7041 was significantly higher in children with BA compared withhealthy …

Lung Function And Exercise Performance Assessment After Inhalation Of Naturally Essential Oils: A Descriptive Observational Study, Hamzeh Al Zabadi, Azmi Hussein, Jamal Shaker, Belal Rahhal, Nidal Amin Jaradat, Malik Al Qub

Chulalongkorn Medical Journal

Background: Essential oils have gained massive attention. We aimed to assess the effects of inhalation ofClinopodium serpyllifolium and Cymbopogon citratus volatile oils on exercise performance and lung function.Methods: Twenty physical education students were randomly assigned into two groups: Clinopodiumserpyllifolium and Cymbopogon citratus (10 participants each). One group was nebulized with Clinopodiumserpyllifolium oil and the other by Cymbopogon citratus oil at a concentration of (0.02 ml/kg of body mass)which was mixed with 2 ml of normal saline before 800 m running tests. Lung function tests were measured usinga spirometer pre and post nebulization.Results: There was a significant increase in Forced Expiratory …

The Role Of Spirituality And 12 Step Groups In Addressing Treatment Fear And Worry Among Head And Neck Cancer Patients, Heather M. Wallace

Open Access Publishing Support Funded Articles

Diagnosis of head and neck squamous cell carcinoma (HNSCC) presents a multifarious problem. Because of uncertainty regarding appropriate clinical treatment, as well as the high potential for disfigurement and functional loss resulting in diminished quality of life (QOL), satisfactory patient participation in quality decision-making is critical. Previous research has consistently revealed that older adults frequently defer decisionmaking to their physician and make decisions more quickly than younger adults. Research also suggests that lay health beliefs, past experiences and various strategies of emotional regulation, based on perceptions of the quantity and quality of remaining time till death, may influence the decisionmaking …

Clinical Evaluators Take Your Mark, Jodi Polaha, Mckenzie Highsmith, William Lusenhop, Deepu George, Adrian Sandoval

ETSU Faculty Works

• Discuss two implementation outcomes (adoption and reach) and explain why they are important for clinicians to measure and report, with application to own work
• Name sources of data that are accessible to clinicians in health care settings, with consideration of own setting.
• Describe a range of dissemination strategies used to create impact, including new ideas for dissemination of own work.

Identifying Intimate Partner Violence: A Review Of Three Measures For Implementation In Primary Care Settings, Matthew W. Henninger, Andrea D. Clements

ETSU Faculty Works

No abstract provided.

Employer Perceptions Of Addiction Recovery And Hiring Decisions, Haley Henderson, Valerie Hoots, Joseph Barnet, Andrea D. Clements

ETSU Faculty Works

Abstract Addiction to drugs and alcohol is a widespread, and ever-growing problem in American society today. Individuals who undergo treatment for their addiction often find it difficult to gain employment due to employers' negative perceptions of addiction. Previous research has found that many employers have a stigma of those in addiction recovery. However, little research has been done to determine if these stigmas affect hiring decisions. Drug and alcohol misuse are prominent in the Appalachian area, which presents an issue for employers in the area who maintain a drug-free work place or who have a stigma of those in addiction …

Hspm 7135-A: Public Health Policy Development & Evaluation, Ho-Jui Tung

College of Public Health: Faculty Syllabi (2014-2021)

This course introduces students to health policy development, analysis and management by examining issues in the health sector. It fosters an appreciation of the complexity of policy problems and provides the basic tools used in public health policy design, implementation and evaluation.

Phld 9231 – Health Informatics & Decision Making, Gulzar H. Shah, Kristie Cason Waterfield

College of Public Health: Faculty Syllabi (2014-2021)

This course focuses on the fundamental concepts of managing information as an asset in public health and healthcare delivery contexts. Emphasis will be placed on converting data into information and converting information into decision support models.

Hadm 7300 – Healthcare Financial Management Ii, James H. Stephens

College of Public Health: Faculty Syllabi (2014-2021)

This course addresses selected financial management concepts and practices in health care organizations. It is a broad introduction to important financial theories, issues, tools and terminology that administrators need to know to manage health care organizations.

The health care environment today places increased emphasis on the financial implications of both managerial and clinical decisions. This emphasis, in turn, has created a need for financial skills among many clinicians and managers that in the past have not been required.

All business decisions have financial implications. As a result, all health care managers must be financially literate so that they can work …

Hadm 7500 - Strategic Planning And Marketing In Health Care, Linda Kimsey

College of Public Health: Faculty Syllabi (2014-2021)

This course offers an introduction to strategic planning and marketing in health services organizations. Processes and formats employed in strategic planning and marketing are presented and applied in case studies and a final project. Elements of market assessment, environmental analysis and strategy development are presented and applied to course practices.

Envh 7233– Environmental Exposure And Impact Assessment, Atin Adhikari

College of Public Health: Faculty Syllabi (2014-2021)

Introduces students to appropriate design, implementation, and analysis of primary environmental exposures and how they are influenced by public health ethics, equity and disparities. Specific topics covered include designing risk profiles; evaluating dose-response relationships; assessing the contribution of public health ethics, equity and disparities to environmental exposures; and analyzing field exposures of toxins.

Epid 7135-A – Epidemiology Of Infectious Disease, (Isaac) Chun Hai Fung

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to provide students with an overview of the principles and practices of infectious diseases epidemiology with focus on how the presence and control of communicable diseases affects public health locally, nationally and internationally. Topics to be covered include: 1) general principles of infectious diseases epidemiology, including outbreak investigation, surveillance, analysis of infectious diseases data, and laboratory testing of specimens; 2) major modes of infectious disease transmission, including airborne, food and water, zoonotic, insect vector, blood, and sexual transmission; 3) different control strategies for infectious diseases, including infection control, antimicrobial management, immunization, risk factor modification, and screening; …

Envh 8335 A – Global Water And Sanitation, Asli Aslan

College of Public Health: Faculty Syllabi (2014-2021)

The global water crisis is the most serious threat to human health. Poor water quality, lack of sanitation and inadequate access to clean water resources are one of the major causes of global health disparities. Current issues such as changing climate, decaying infrastructure and reemerging waterborne diseases are also contributors for disease transmission within vulnerable populations. This course analyzes the key drivers that affect global water quality and human health. Real world case scenarios will be examined to develop sustainable and appropriate solutions that consider environmental, individual, cultural, and economic factors.

Chbe 9335 A – Global Health And Preparedness, Andrew Hansen

College of Public Health: Faculty Syllabi (2014-2021)

This course will focus on global public health and preparedness for domestic and global emergencies. Students will explore patterns of health and disease around the world, and compare them to public health issues in the United States. An ecological framework will be employed to illustrate the complex political, social, economic, and environmental determinants of global health inequity. Concepts from the social sciences, epidemiology, health systems, and policymaking will be incorporated. The course will emphasize issues related to humanitarian emergencies and natural disasters both globally and domestically, and the need to build public health infrastructure and preparedness to mitigate them.

Syllabus: Bios 9132 – Advanced Clinical Trial Methodology, Karl E. Peace

College of Public Health: Faculty Syllabi (2014-2021)

Students are introduced to regulatory, scientific, statistical and practical aspects of methods inherent in design, monitoring and analyzing clinical trials. Clinical trials in many areas of drug development are presented, discussed and critiqued.

Bios 9130—Research Seminar In Biostatistics, Robert Vogel

College of Public Health: Faculty Syllabi (2014-2021)

This course is designed to provide the student with the current best practices in biostatistical consulting. Topics include: Identifying and constructing appropriate questions to ask clients regarding their consultation request, an overview of appropriate statistical methods and SAS software procedures to use for specific study designs and statistical analysis of collected data, directing a consultation appointment without faculty lead, conducting exploratory data analyses, conducting effective analyses based on appropriate statistical methods, conducting needed simulation (including Monte Carlo methods and Bootstrap methods) and providing oral and written communication of statistical findings. 3 credit houses

Bios 6135: Topics Of Inference In Biostatistics, Lili Yu

College of Public Health: Faculty Syllabi (2014-2021)

(taken from 2018-19 Course Catalog): This course provides an introduction to the fundamental knowledge of derivatives, integrals, and matrix algebra found in biostatistical inference. The course will introduce the theory of quadratic forms and their applications to distributions, the method of maximum likelihood estimation, likelihood ratio tests, restricted maximum likelihood, and the basis for inferences derived from hypothesis testing and confidence intervals. Emphasis will be placed on how these techniques are used in biostatistical problems and applications using examples from the pharmaceutical industry.