Medicine and Health Sciences Commons^™

Artificial Intelligence And The Challenge For Rural Medicine, James Denvir

Marshall Journal of Medicine

Recent advances in artificial intelligence, machine learning, and deep learning are beginning to have an impact on everyday experiences, from natural language processing used in automated telephone call centers to semi-autonomous vehicles. These techniques have also been applied to medical care. In this editorial we discuss applications of AI to medicine and argue for a proactive approach to include rural medicine in this paradigm shift.

Pigmentary And Other Dermatologic Manifestations Of Minocycline: A Reminder Of Adverse Effects, Kayla Rodriguez, Courtney Wellman, Adam M. Franks, Kimberly Mcclelland, Tammy Bannister

Marshall Journal of Medicine

The applications of the tetracycline class of antibiotics extends beyond their antimicrobial activity to anti-inflammatory, immunosuppressive and neuroprotective applications making it a commonly used class of medication. Minocycline, a second generation tetracycline, has inherent characteristics that improve absorption and distribution. These benefits promote even more wide spread use. This familiarity of usage breeds prescriptive complacency toward the dermatologic complications including hyperpigmentation. The following case explores these adverse manifestations of Minocycline use.

Acute Diagnosis Of Wilson’S Disease In A Teenage Patient, Sarah Irvin, Ryan Mccarthy

Marshall Journal of Medicine

Wilson’s Disease, a rare autosomal recessive genetic disease, is caused by a mutation in the ATP7B enzyme gene. Without this enzyme, copper builds up in the brain, liver, and cornea causing a multitude of symptoms. It is important to consider Wilson’s disease because the prognosis is dependent on timely diagnosis. This is an interesting case of a 19-year-old male who presented with suicidal thoughts and rapid weight loss. After many months and an extensive work-up, Wilson’s Disease was diagnosed. Due to his rapid decline, he was transferred to a larger university healthcare center where he is currently enrolled in clinical …

Is Napping A Good Thing?, Sammar Atassi

Marshall Journal of Medicine

This article aims to explore new findings in research in the relationship between sleep disorders and dementia. The new research questions the glymphatic system's role in clearing the toxic proteins from the brain during sleep.

Case Reports: Add Value Beyond The Impact Factor, Darshana T. Shah

Marshall Journal of Medicine

No abstract provided.

Evaluating Feline Release Criteria Following Iodine-131 Therapy For Hyperthyroidism, Anthony Davila

LSU Master's Theses

Hyperthyroidism is a very common endocrine disorder in both humans and cats. Radioactive iodine ablation therapy is considered the gold standard; however, the patient becomes a radiation source and poses a potential radiological risk to others. The regulations governing when the patient can be released differ between human medicine and veterinary medicine. A human patient can receive up to 33 mCi of I-131 and be discharged the same day; yet a feline patient can receive a dose as low as 2 mCi and require multiple days of hospitalization. This discrepancy has not been satisfactorily addressed; and overly restrictive release criteria …

Unlocking Data To Deliver Infant Mortality Solutions, Kylie Veleta

Innovation and SimLab

No abstract provided.

Deepcon-Pre: Improved Protein Contact Map Prediction Using Inverse Covariance And Deep Residual Networks, Nachammai Palaniappan

Theses

As with most domains where machine learning methods are applied, correct feature engineering is critical when developing deep learning algorithms for solving the protein folding problem. Unlike the domains such as computer vision and natural language processing, feature engineering is not rigorously studied towards solving the protein folding problem. A recent research has highlighted that input features known as precision matrix are most informative for predicting inter-residue contact map, the key for building three-dimensional models. In this work, we study the significance of the precision matrix feature when very deep residual networks are trained. Using a standard dataset of 3456 …

Split Selectable Markers., Nathaniel L. Jillette, Menghan Du, Jacqueline Jufen Zhu, Peter Cardoz, Albert W Cheng

Faculty Research 2019

Selectable markers are widely used in transgenesis and genome editing for selecting engineered cells with a desired genotype but the variety of markers is limited. Here we present split selectable markers that each allow for selection of multiple "unlinked" transgenes in the context of lentivirus-mediated transgenesis as well as CRISPR-Cas-mediated knock-ins. Split marker gene segments fused to protein splicing elements called "inteins" can be separately co-segregated with different transgenic vectors, and rejoin via protein trans-splicing to reconstitute a full-length marker protein in host cells receiving all intended vectors. Using a lentiviral system, we create and validate 2-split Hygromycin, Puromycin, Neomycin …

Relationship Between Smoking Habit And Sperm Parameters Among Patients Attending An Infertility Clinic, Rehana Rehman, Nida Zahid, Sofia Amjad, Mukhtiar Baig, Zohair Jamil Gazzaz

Department of Biological & Biomedical Sciences

Background: This study aimed to estimate stress markers, oxidative stress (OS), reproductive hormones and sperm parameters in male smokers and non-smokers and observe the impact of oxidative stress markers and smoking on sperm count, motility and morphology in a selected population of Karachi, Pakistan.
Methods: This cross-sectional study was conducted from July 2017 to July 2018 at Aga Khan University (AKU), in Karachi, Pakistan. The subjects were recruited from the Sindh Institute of Reproductive Medicine (SIRM), Karachi based on defined inclusion criteria. The subjects were categorized into fertile and infertile based on cut off values of sperm parameters as recommended …

Dépression Et Douleurs Musculosquelettiques : Évaluation Préliminaire D'Une Approche De Réadaptation Axée Sur La Promotion Du Retour Au Travail, Michael J. L. Sullivan, Timothy Wideman, Aliki Thomas

Rapports de recherche scientifique

Nombre de personnes ayant subi une blessure au travail présentent des symptômes de douleur et de dépression. La combinaison de symptômes de douleur et de dépression peut avoir un effet négatif sur le rétablissement de l’individu. La présence de symptômes de dépression peut nuire à la capacité d’accomplir de nombreuses activités importantes de la vie quotidienne, inclusion faite des activités professionnelles. Des études ont démontré que les travailleurs blessés qui présentent des symptômes de dépression demeurent absents du travail deux fois plus longtemps que les travailleurs blessés non dépressifs. Les interventions utilisées pour traiter la douleur et l’incapacité fonctionnelle chez …

Preliminary Evaluation Of An Approach To Rehabilitation Aimed At Promoting Return-To-Work In Individuals With Co-Morbid Musculoskeletal Pain And Depression, Michael J. L. Sullivan, Timothy Wideman, Aliki Thomas

Rapports de recherche scientifique

Nombre de personnes ayant subi une blessure au travail présentent des symptômes de douleur et de dépression. La combinaison de symptômes de douleur et de dépression peut avoir un effet négatif sur le rétablissement de l’individu. La présence de symptômes de dépression peut nuire à la capacité d’accomplir de nombreuses activités importantes de la vie quotidienne, inclusion faite des activités professionnelles. Des études ont démontré que les travailleurs blessés qui présentent des symptômes de dépression demeurent absents du travail deux fois plus longtemps que les travailleurs blessés non dépressifs. Les interventions utilisées pour traiter la douleur et l’incapacité fonctionnelle chez …

An Exploration Of Automated Narrative Analysis Via Machine Learning, Sharad Jones, Carly Fox, Sandra Laing Gillam, Ronald B. Gillam

Communicative Disorders and Deaf Education Faculty Publications

The accuracy of four machine learning methods in predicting narrative macrostructure scores was compared to scores obtained by human raters utilizing a criterion-referenced progress monitoring rubric. The machine learning methods that were explored covered methods that utilized hand-engineered features, as well as those that learn directly from the raw text. The predictive models were trained on a corpus of 414 narratives from a normative sample of school-aged children (5;0-9;11) who were given a standardized measure of narrative proficiency. Performance was measured using Quadratic Weighted Kappa, a metric of inter-rater reliability. The results indicated that one model, BERT, not only achieved …

Interventions To Improve Older Driver Safety, Bernadette A. Fausto

USF Tampa Graduate Theses and Dissertations

Increased longevity coupled with age-related declines that compromise driving safety and fragility render older adults as vulnerable road users (Oxley & Whelan, 2008). To address this public health concern, researchers continue to investigate interventions to improve older driver safety. The current dissertation consists of two papers examining: a) the state of the literature on older driver interventions and b) the efficacy of one approach, Useful Field of View cognitive training, to reduce at-fault crash involvement. The first paper sought to identify and quantify the effects of different interventions among older adults on outcomes of crashes, on-road driving performance, self-reported outcomes …

Pole Dancing For Fitness: The Physiological And Metabolic Demand Of A 60-Minute Class, Joanna C. Nicholas, Kirsty Mcdonald, Peter Peeling, Ben Jackson, James Dimmock, Jacqueline A. Alderson, Cyril J. Donnelly

Research outputs 2014 to 2021

Nicholas, JC, McDonald, KA, Peeling, P, Jackson, B, Dimmock, JA, Alderson, JA, and Donnelly, CJ. Pole dancing for fitness: The physiological and metabolic demand of a 60-minute class. J Strength Cond Res 33(10): 2704–2710, 2019—Little is understood about the acute physiological or metabolic demand of pole dancing classes. As such, the aims of this study were to quantify the demands of a standardized recreational pole dancing class, classifying outcomes according to American College of Sports Medicine (ACSM) exercise-intensity guidelines, and to explore differences in physiological and metabolic measures between skill- and routine-based class components. Fourteen advanced-level amateur female pole dancers …

Rabies Surveillance Identifies Potential Risk Corridors And Enables Management Evaluation, Amy J. Davis, Kathleen M. Nelson, Jordana D. Kirby, Ryan M. Wallace, Xiaoyue Ma, Kim M. Pepin, Richard B. Chipman, Amy Gilbert

United States Department of Agriculture Wildlife Services: Staff Publications

Intensive efforts are being made to eliminate the raccoon variant of rabies virus (RABV) from the eastern United States and Canada. The United States Department of Agriculture (USDA) Wildlife Services National Rabies Management Program has implemented enhanced rabies surveillance (ERS) to improve case detection across the extent of the raccoon oral rabies vaccination (ORV) management area. We evaluated ERS and public health surveillance data from 2006 to 2017 in three northeastern USA states using a dynamic occupancy modeling approach. Our objectives were to examine potential risk corridors for RABV incursion from the U.S. into Canada, evaluate the effectiveness of ORV …

Speech-Language Pathologist–Guided Morphological Awareness Instruction In The General Education Classroom, Victoria Henbest

Victoria S. Henbest Publications

Research has shown that instruction in morphological awareness improves students' understanding and use of affixes. However, morphological awareness instruction, typically, is not provided in the general education classroom, and there are few documented collaborations between teachers and speech-language pathologists (SLPs), the latter of whom have a unique expertise in language. Thus, the purpose of this article was to determine the feasibility of an SLP-guided morphological awareness instructional program in a general education classroom.After completing a webinar training in morphological awareness, 2 general education teachers implemented morphological awareness lessons in their classrooms over an 8-week period. The teachers and collaborating SLP …

Gilteritinib Or Chemotherapy For Relapsed Or Refractory Flt3-Mutated Aml, Alexander E. Perl, Giovanni Martinelli, Jorge E. Cortes, Andreas Neubauer, Ellin Berman, Stefania Paolini, Pau Montesinos, Maria R. Baer, Richard A. Larson, Celalettin Ustun, Francesco Fabbiano, Harry P. Erba, Antonio Di Stasi, Robert Stuart, Rebecca Olin, Margaret Kasner, Fabio Ciceri, Wen-Chien Chou, Nikolai Podoltsev, Christian Recher, Hisayuki Yokoyama, Naoko Hosono, Sung-Soo Yoon, Je-Hwan Lee, Timothy Pardee, Amir T. Fathi, Chaofeng Liu, Nahla Hasabou, Xuan Liu, Erkut Bahceci, Mark J. Levis

Department of Medical Oncology Faculty Papers

BACKGROUND: Patients with relapsed or refractory acute myeloid leukemia (AML) with mutations in the FMS-like tyrosine kinase 3 gene (FLT3) infrequently have a response to salvage chemotherapy. Gilteritinib is an oral, potent, selective FLT3 inhibitor with single-agent activity in relapsed or refractory FLT3-mutated AML.

METHODS: In a phase 3 trial, we randomly assigned adults with relapsed or refractory FLT3-mutated AML in a 2:1 ratio to receive either gilteritinib (at a dose of 120 mg per day) or salvage chemotherapy. The two primary end points were overall survival and the percentage of patients who had complete remission …

Evaluating The Effect Of Temperature On A Human Parasite And Its Intermediate Snail Host: Implications For A Changing Climate, Karena H. Nguyen

USF Tampa Graduate Theses and Dissertations

Global climate change is impacting the emergence, re-emergence, prevalence, and incidence of infectious diseases worldwide, including parasitic diseases of humans (Blum and Hotez 2018). Neglected tropical diseases, defined as a group of parasitic diseases affecting developing countries in the tropics (Hotez et al. 2007), are of particular concern because these diseases occur in areas that are also expected to experience rapid population growth and agricultural development in the coming decades. As human population and food demand increase, the greater the likelihood of humans encountering intermediate hosts that either inhabit agricultural areas or are impacted by agricultural development, which will influence …

Power In The Counseling Relationship: The Role Of Ignorance, Izaak L. Williams, Peg O'Connor

Journal of Human Services: Training, Research, and Practice

This article explores the role of therapist self-disclosure in clinical settings. Distinctions are made between the enmeshed concepts of privacy, secrecy, and confidentiality to elucidate the role of ignorance in maintaining the power dynamics in therapeutic relationships. While some measure of privacy is essential to counseling practice, secretive behavior (in which the counselor divulges too little about themselves) can have a negative impact on the therapeutic relationship and the client’s therapeutic outcomes. There is, therefore, an under-appreciated and delicate balancing act between withholding information to protect the client and the counselor and revealing enough personal details to empower the client’s …

Near Real-Time Determination Of The Prevalence Of Cannabinoids, Cathinones, And Synthetic Opioids, Catherine O'Rourke, Bikram Subedi

Scholars Week

Unregulated new psychoactive substances (NPS) in “pure” or “preparation” forms are designed to mimic the effects of controlled substances, and are introduced and reintroduced in the market as a cheap substitute of established regulated drugs in quick succession to loophole the law enforcement efforts on combating drugs. For example, carfentanil, a synthetic opioid activates the opioid receptors similar to morphine but it is astoundingly potent compared to a typical drug of abuse (100 times more potent than fentanyl and 10,000 times more powerful than morphine). Based on the cost- and time-intensive forensic analysis, National Drug Early Warning System reported the …

Student Perceptions Of Academic Effort In Applied Science Courses, Ragan Harris

Scholars Week

Student Perceptions of Academic Effort in Applied Science Courses: A Pilot Study

Ragan Harris

Dr. Priscilla Maghrabi

Dr. Brenda Reeves

Applied Health Sciences

Many applied science programs such as exercise science include prerequisite courses in the basic sciences to provide students with knowledge of foundational principles as well as provide transfer pathways from biology. However, when students begin exercise science coursework, their perceptions are that these courses should be easier, expecting lower effort and higher academic grades. These mismatched perceptions often lead to academic frustration. To determine the validity of the perceptions of high vs. low academic effort and academic …

Harbor Branch Oceanographic Institute Summer Intern Program, Nicolas Vitari

Trick to the Treat of Internships and Research

No abstract provided.

Md Anderson University Outreach Summer Program, Melanie Fraidenburg

Trick to the Treat of Internships and Research

No abstract provided.

University Of Miami Summer Undergraduate Research Fellowship (Surf), Elizabeth Feldman

Trick to the Treat of Internships and Research

No abstract provided.

Clear Vision Optometry Clinic Internship, Taylor Veneza

Trick to the Treat of Internships and Research

No abstract provided.

A Sound-Sensitive Source Of Alpha Oscillations In Human Non-Primary Auditory Cortex, Alexander J. Billig, Björn Herrmann, Ariane E. Rhone, Phillip E. Gander, Kirill V. Nourski, Beau F. Snoad, Christopher K. Kovach, Hiroto Kawasaki, Matthew A. Howard, Ingrid S. Johnsrude

Brain and Mind Institute Researchers' Publications

Copyright © 2019 Billig, Herrmann et al. The functional organization of human auditory cortex can be probed by characterizing responses to various classes of sound at different anatomical locations. Along with histological studies this approach has revealed a primary field in posteromedial Heschl's gyrus (HG) with pronounced induced high-frequency (70-150 Hz) activity and short-latency responses that phase-lock to rapid transient sounds. Low-frequency neural oscillations are also relevant to stimulus processing and information flow, however, their distribution within auditory cortex has not been established. Alpha activity (7-14 Hz) in particular has been associated with processes that may differentially engage earlier versus …

Love & Angels Care Internship, Kristin Addison

Trick to the Treat of Internships and Research

No abstract provided.

2019 Celebration Of Scholarship, Creativity, And Engagement, Beth Heldebrandt, Todd Bruns, Seth Yeakel, Matthew Eifrid

Programs

Scholarship, creativity, innovation, and the many forms of collaborative engagement that shape faculty life and student learning are central to the mission of Eastern Illinois University. For that reason, our faculty, department chairs, college deans, the Provost, and the entire campus community celebrate the achievements and outstanding contributions of our colleagues and students to their disciplines and professions every year. And, as the following pages illustrate, faculty engaged in continuing scholarly and creative activities that have provided outstanding mentoring experiences for our undergraduate and graduate students.

In addition to recognizing faculty performances, shows, publications, grants and other professional efforts, the …

Analisis Produk Layanan Rawat Inap Di Rsud Wangaya Denpasar Berdasarkan Stp (Segmenting, Targeting, Positioning) Dan 4 P (Product, Price, Place, Promotion), Ni Putu Sri Wahyuni

Jurnal ARSI : Administrasi Rumah Sakit Indonesia

Service marketing strategy will increase the level of customer satisfaction with marketing mix consisting of 4 P (product, price, place, promotion) and supported by modern STP marketing strategies (Segmenting, Targeting and Positioning) as a technique to look for market opportunities, so that the hospital is able to provide health services according to customer needs. Descriptive research has been conducted to describe a situation objectively, to solve the problem being faced. The data used are secondary data that includes inpatient visit data, occupancy data for inpatient rooms, and community satisfaction data in inpatient rooms. Based on the results of the study, …