Medicine and Health Sciences Commons^™

Resilient Aging: Maximizing Functional Abilities Of Aging Adults, Casey M. Perkins

MOT Student Capstones

The Resilient Aging program aims to educate fitness trainers and other movement professionals who work with community-dwelling older adults in order to help them provide the best exercise programs for overall wellness. Training from the program includes education regarding a variety of restorative movements, stretching, positional transitions. proprioceptive training, balance, and strengthening exercise in multiple planes with a variety of loads to maximize the functional abilities, and resilience of the elderly participants, with outcomes aimed at improving the movement professionals" understanding of these topics. The program promotes the client participation in occupations by providing education to movement professionals regarding not …

Helicobacter Pylori Infection And Its Importance In The Development Of Idiopathic Thrombocytopenic Purpura, Zilola Khashimova

Physician Assistant Studies | Faculty Scholarship

Helicobacter Pylori (HP) infection has been associated with chronic inflammation of the stomach and may also be associated with Idiopathic thrombocytopenic purpura (ITP). A literature review was conducted on the reported research of HP infection associated with ITP.

Impact Of The First Covid-19 Shelter-In-Place Order In The United States On Emergency Department Utilization, Marin County, California, Brett R. Bayles, Michaela George, Haylea Hannah, Patti L. Culross, Rochelle Ereman, Dustin W. Ballard, Matthew Willis

Global Public Health | Faculty Scholarship

Background The first shelter-in-place (SIP) order in the United States was issued across six counties in the San Francisco Bay Area to reduce the impact of COVID-19 on critical care resources. We sought to assess the impact of this large-scale intervention on emergency departments (ED) in Marin County, California.

Methods We conducted a retrospective descriptive and trend analysis of all ED visits in Marin County, California from January 1, 2018 to May 4, 2020 to quantify the temporal dynamics of ED utilization before and after the March 17, 2020 SIP order.

Results The average number of ED visits per day …

Chest Ct Vs. Reverse Transcription Polymerase Chain Reaction Testing For Covid Diagnosis, Megan Chlebove

Medical Imaging Senior Posters

This project explains reverse transcription polymerase chain reaction tests (RT-PCR), how they are used to test patients for coronavirus disease (COVID-19), and how chest computed tomography (CT) imaging can assist in diagnosis. False negatives in RT-PCR testing, ground glass opacities (GGOs), pros and cons of using CT and RT-PCR tests together for diagnosis, and the use of artificial intelligence to diagnose COVID on a CT image are also discussed. COVID is a respiratory disease discovered in December of 2019 in Wuhan, China and has spread to the entire world. RT-PCR tests are the main form of diagnosis of COVID and …

Breast Lesion Localization: Savi Scout, Madison L. Keegan

Medical Imaging Senior Posters

Breast Lesion Localization: Savi Scout

Madison Keegan

Faculty Advisor: Dr. Elaine Halesey, Ed.D., R.T.(R)(QM)

The Savi Scout is a localization procedure used to help identify non-palpable breast lesions under mammographic or ultrasound guidance, by way of placement of a non-radioactive reflector through a delivery system. The modality of mammography uses screening and diagnostic exams by creating images of the breast to better visualize anatomy as well as possible lesions. The radiographic detail determines the type of breast tissue such as fatty, dense, or extremely dense and with age the tissue type can change. Non-palpable breast lesions are identified with imaging …

Interventional Balloon Kyphoplasty In Multiple Myeloma Patients, Mary Dziadosz

Medical Imaging Senior Posters

This poster project explains an interventional radiology (IR) procedure called Balloon Kyphoplasty (BKP). BKP is a procedure that involves the insertion of cement into the vertebral column due to vertebrae fractures throughout the spine. Vertebral fractures can happen due to a number of reasons, however, multiple myeloma is the main focus of this project. Multiple Myeloma (MM) is the second most hematological malignancy and there is no cure. MM affects several parts of the body but the most common are the skull, vertebral column, long bones, and the hip and pelvis region. There are several advantages to having BKP done. …

Interventional Breast Imaging, Agripina Torres

Medical Imaging Senior Posters

Interventional breast imaging is essential in the diagnosis of abnormal findings in the breast tissue. Interventional breast imaging began as an open excision; the breast was biopsied through a surgical procedure that required the whole breast to be excised, thus allowing a sample of the breast tissue to be obtained. With this type of biopsy, the patient would have a longer recovery time, a higher cost, and, in some cases, unnecessary excisions. Image guided breast intervention, however, has led to the decline of open excisions. Biopsies performed under the guidance of an imaging modality allow breast interventions to be safe, …

The Impact Of Covid-19 On Radiation Oncology Treatments, Lauren Fink

Medical Imaging Senior Posters

When the COVID-19 pandemic began, hospitals became overwhelmed. There was a lack of personal protective equipment (PPE) and a lack of capacity within emergency departments, which caused a panic amongst medical facilities. Facilities were forced to prioritize patients and cancel appointments that were not urgent. Many doctors’ appointments were switched to tele-visits to limit exposure to the virus and to allow priority to COVID-19 patients. Not only were diagnostic testing and treatments postponed or canceled, but news was published that those who were immunosuppressed need to take extra precautions because the risk of fatality is greater for those with preexisting …

Digital Breast Tomosynthesis For Dense Breasts, Emily Kerbaugh

Medical Imaging Senior Posters

Digital breast tomosynthesis (DBT), also referred to as three-dimensional digital mammography provides a new technique that can aid in dense breast imaging. Mammography is the process of creating images of the breast for screening and diagnostic purposes by using low dose radiation. Screening mammograms are performed once a patient is age forty and then annually after that. It is used to provide an earlier detection of breast cancer for a better chance of survival. Diagnostic mammograms are performed when a patient has a strong family history of breast cancer or clinical evidence, such as, a breast lump. Most cancerous lesions …

Age Differences In Hippocampal Glutamate Modulation During Associative Learning And Memory: A Proton Functional Magnetic Resonance Spectroscopy (1h Fmrs) Study, Chaitali Anand

Wayne State University Dissertations

Episodic and associative memory decline is one of the earliest cognitive impairments in normal aging and among the defining cognitive features of Alzheimer’s disease (AD). Since, age-related cognitive decline gradually devolves into AD, with neuropathology preceding cognitive changes by many years, the identification of biomarkers of early disease progression is crucial. Reduction in glutamate, the main excitatory neurotransmitter involved in associative memory, in key brain regions such as the hippocampus, has been theorized as one of the cellular mechanisms underlying cognitive decline in aging and AD. A few neuroimaging studies that demonstrated a link between older adults’ weaker cognitive performance …

Congenital Morgagni Hernia Presenting As Complete Small Bowel Obstruction In The Adult - A Case Report, Sabah Uddin Saqib, Kulsoom Hamid, Tabish Umer Chawla

Section of General Surgery

Introduction: Congenital Diaphragmatic hernia (CDH) is a condition in which there is a defect in the diaphragm present at the time of birth. Morgagni hernia is one of the two most common types of CDH which constitutes 2%-4% of diaphragmatic hernias. They mostly remain silent or discovered as an incidental finding on radiological studies. Symptomatic adult Morgagni hernias are extremely rare.
Presentation of case: Elderly woman presented with a 1-day history of abdominal pain, vomiting, and acute onset of respiratory distress. There was no history of trauma to the chest or abdomen. After initial resuscitation, a Chest x-ray was performed …

Advances In Targeted Therapy For Acute Myeloid Leukemia., Jifeng Yu, Peter Y Z Jiang, Hao Sun, Xia Zhang, Zhongxing Jiang, Yingmei Li, Yongping Song

Articles, Abstracts, and Reports

Acute myeloid leukemia (AML) is a clonal malignancy characterized by genetic heterogeneity due to recurrent gene mutations. Treatment with cytotoxic chemotherapy has been the standard of care for more than half of a century. Although much progress has been made toward improving treatment related mortality rate in the past few decades, long term overall survival has stagnated. Exciting developments of gene mutation-targeted therapeutic agents are now changing the landscape in AML treatment. New agents offer more clinical options for patients and also confer a more promising outcome. Since Midostaurin, a FLT3 inhibitor, was first approved by US FDA in 2017 …

New Approach To Health And The Environment To Avoid Future Pandemics, Serge Morand

Animal Sentience

This commentary expands Wiebers & Feigin’s target article by pinpointing how declining wildlife, expanding livestock and globalisation contribute to the increase in epidemics of zoonotic diseases, the COVID-19 crisis and future health crises. Epidemics and the emergence of zoonoses are manifestations of dysfunctional links with animals, both wild and domestic, requiring a new approach to health and the environment.

Challenging Aggressive Behaviors Experienced By Personal Support Workers In Comparison To Home Care Workers: Relationships Between Caregiver Experiences And Psychological Health, Kelsey N. Womack, Teala W. Alvord, Caitlyn F. Trullinger-Dwyer, Sean P.M. Rice, Ryan Olson

OHSU-PSU School of Public Health Faculty Publications and Presentations

Personal support workers (PSW) are caregivers for children and adults with intellectual and developmental disabilities (IDDs) or adults experiencing mental illness or other behavioral health conditions. The work can be very meaningful, but many PSWs must prepare for, monitor, and manage challenging behaviors, including aggression. This study was designed to estimate the prevalence of aggression experienced by PSWs in Oregon, and compare it to a previous sample of Oregon home care workers (HCWs). This comparison included an analysis of relationships between exposures to aggression and psychological health factors. PSWs in Oregon (N = 240) were surveyed electronically at a single …

Awareness Of The Unaware: Anosognosia As A Comorbidity In Mental Health Conditions, Tiffany L. Baula

Honors Undergraduate Theses

The primary purpose of this integrative review of the literature is to describe healthcare provider’s recognition of anosognosia in individuals with comorbid mental health disorders, as a differentiating diagnosis needing preeminent early intervention. The secondary purpose is to examine how anosognosia influences outcomes in the population of individuals with severe mental illness. It is expected that early recognition by clinicians and implementation of additional interventions to address anosognosia as the most influential comorbidity of schizophrenia, will decrease exacerbations and improve treatment and patient outcomes.

A literature review exploring clinician’s acknowledgement of anosognosia was performed using various databases. Search terms included: …

Professional Liability Insurance For Athletic Trainers: A Cross Sectional Study Of Athletic Trainers Who Do Per Diem Work, Kameelah J. Belgrave

Honors Undergraduate Theses

Context: Many secondary school athletic trainers (ATs) complete per diem work as a way to supplement their income. Working per diem means the AT provides services to events that are not part of their main employment. Since this type of work is not connected to their main employment, the AT may lack appropriate professional liability insurance (PLI). PLI is a type of insurance that protects healthcare professionals from bearing the entire cost of defending a malpractice claim made by a former or current patient. Anecdotally, many ATs believe that the PLI provided by their main employer covers all health care …

The Effects Of Vaping On Oral Streptococci And Oral Inflammation, Matthew Caldwell

Honors Undergraduate Theses

E-cigarette (e-cig) use is rising, but much is unknown about the effects of its vapor. This vapor contains chemicals such as propylene glycol, a known antimicrobial, and nicotine, whose derivatives are carcinogenic. Here, we study the effects of vaping on resident bacteria of the oral cavity and on oral cell inflammation. Oral streptococci are major residents in the oral cavity, with S. mutans the primary cause of dental caries. Growth and biofilm formation have been shown to be enhanced upon exposure to traditional cigarette smoke in vitro. In this study, we analyzed the effects of e-cig vapor on growth …

Cerium Oxide Nanoparticles And Beneficial Bacteria: Two Novel Treatments For Eradicating Bacteria Associated With Prosthetic Infection?, Etta Conteh

Honors Undergraduate Theses

The purpose of this thesis was to investigate new possible compounds that can be used to treat orthopedic implant infections caused by bacterial pathogens. Current treatment includes the use of antibiotics and the DAIR procedure, which stands for debridement, antibiotic therapy, irrigation, and retention. However, antibiotics are becoming less effective as a treatment due to bacteria gaining antibiotic resistance. Two bacterial species involved in orthopedic implant infections are P. aeruginosa and S. aureus. This thesis investigated cerium oxide nanoparticles and L. fermentum, a beneficial bacterium, as possible treatments to stop bacterial growth and the formation of biofilm. This …

Exploring The Different Factors Associated With Burnout, Natassja J. Debra

Honors Undergraduate Theses

Maslach and Leiter determined burnout to be caused by three major components: exhaustion, cynicism, and inefficiency. This literature review focuses on factors that directly contribute to new graduate nurse burnout. Major factors discussed in this paper are differences in expectations versus reality, influences from past education, developing professional identity, and the effect of the workplace environment on new graduate transition. Interventions to combat burnout are discussed along with recommendations for future research.

Detection Of A Peptide Hormone - Somatostatin - Label-Free Split-Aptameric Probes, Charles A. Dowis

Honors Undergraduate Theses

Peptide hormones are important biomolecules that transduce downstream effects such as cell proliferation, regulation, and gene expression. Their levels have been upregulated in various disorders such as cancer, yet detection methods are lacking. We designed two split aptamer-based assays for the detection of a peptide hormone – Somatostatin (SST) – with different signal readouts: fluorescent readout based on light-up aptamers and the colorimetric readout of ABTS peroxidation from a G-quadruplex. We used an already selected split-aptamer –SSTA5–for SST for our designs and we had expected the developed detection systems to exhibit detection and quantification capabilities that would hopefully allow their …

Using Cellphones To Advance Diabetic Foot Care Practice: A Review Of The Literature, Qiuna Fang

Honors Undergraduate Theses

Preventing diabetic foot ulcers among patients diagnosed with diabetes is an important element of care as diabetic foot ulcers present major medical, psychosocial and economic threats. In addition, about 20% of the diabetic foot ulcer cases will ultimately require amputation and cause greater mortality rates. The purpose of this literature review was to evaluate cellphone use to promote diabetic foot care practices among patients with diabetes. Six electronic databases were searched for articles which included text messaging and or phone interventions geared at improving foot care practices. A total of 14 articles dated 2009-2019 met the inclusion criteria and were …

Evaluating The Nutritional Status Of Peruvian Born Children, Chantelle Garcia Medina

Honors Undergraduate Theses

Background: Rural areas of Peru lack access to healthcare resources and poor nutritional knowledge of what should be given to their children throughout their growth and development. The majority of the rural areas rely on a high carbohydrate, moderate vegetable diet, and lacking a protein source. Lower protein intake can lead to problems of malnutrition and growth stunting. Families rarely have monetary resources to provide a protein at every meal for the entire family. There is also a lack of a clean water supply, free of parasites and helminths. Caregivers often rely on replenishing intake with other fluids high …

Interventions For Cultivating Civility In The Healthcare Team: Review Of The Literature, Elizabeth Knapp

Honors Undergraduate Theses

OBJECTIVE: The aim of this literature review was to examine the most current research regarding effective, evidence-based programs for reducing incivility among the healthcare team, particularly nurses. BACKGROUND: Incivility in the work environment is linked to a variety of negative outcomes, including diminished productivity, impaired judgement, and reduced employee retention. Incivility is especially detrimental to the healthcare team because it is correlated with decreased quality of patient care and increased medical errors. Despite regulations and statements made by the Joint Commission and the American Nurses Association to combat this serious problem, incivility continues to plague healthcare. METHODS: …

Investigating Aggression In Huntington Disease, Chloe E. Larochelle

Honors Undergraduate Theses

Huntington Disease (HD) is a neurodegenerative disorder that is caused by a CAG trinucleotide repeat expansion in the huntingtin gene. The onset of the disease is defined by the presence of motor deficits, such as chorea. However, cognitive and psychiatric symptoms often develop before motor onset and typically have a larger impact on patient quality of life. Psychiatric symptoms include depression, anxiety, and OCD, but also aggression and irritability, which have been comparatively understudied due to stigma. Currently, treatments to modify these behaviors in premanifest HD patients are not consistently effective and often have side effects, creating a need for …

The Relationship Between Community Health Worker Supply And The Rate Of Preventable Hospitalizations Of Rural Latinos With Diabetes, Danielle O. Mapp

Honors Undergraduate Theses

The ever-increasing prevalence of diabetes mellitus and its associated healthcare costs in the United States has led to our healthcare system's need for cost-effective health resources and chronic disease management. The interventions of Community Health Workers (CHWs) can cost-effectively improve population health and prevent the unnecessary utilization of some medical services especially in rural, low-income, minority populations, where there is often limited access to healthcare. The purpose of this study is to investigate the relationship between the number of total CHWs in rural counties and the mean diabetes-related preventable hospitalization rates in Latino patients diagnosed with diabetes in those rural …

The Effects Of Roundup On The Life History, Stress Response, And Immune Function Of The Yellow Fever Mosquito, Aedes Aegypti, Lindsay E. Martin

Honors Undergraduate Theses

Aedes aegypti mosquitoes, vectors for many human diseases, begin life as larvae developing in water, potentially exposed to runoff with herbicides and pesticides. This study serves as a novel investigation into the transstadial effects of exposure to Roundup on A. aegypti life history, immunity, and stress response and aims to account for these effects in an R0 model for vectorborne disease transmission. Prior work has shown that Roundup negatively affects mosquito life history. I hypothesized that larval exposure to the maximum sublethal dose of Roundup (7189µg/L) would negatively impact A. aegypti life history, immunity (candidate gene approach), and stress response …

Exploring The Impact Of Pre-Exposure Prophylaxis Related To Sexual Behavior In College Men, Dalton J. Poe

Honors Undergraduate Theses

Pre-exposure prophylaxis (PrEP) is an effective tool for preventing human immunodeficiency virus (HIV) acquisition in sexually active at-risk individuals such as men who have sex with men (MSM). The purpose of this study is to examine factors associated with intent to engage in risky sexual behavior among HIV-negative college aged (18-24) MSM who are currently adherent to PrEP or who have expressed interest in the future adoption of PrEP. A multiracial/ethnic sample of 31 men expressing interest in the adoption of PrEP and 6 men currently taking PrEP completed a quantitative survey identifying key themes regarding attitudes towards PrEP and …

The Impact Of Virtual Reality On Chronic Pain, Alexis Whitehead

Honors Undergraduate Theses

Chronic pain remains a prevalent problem across the United States. Chronic pain does not seem to have a function and relief of this symptom remains elusive for many sufferers. Virtual reality has been used as an adjunct therapy to decrease acute pain with promising results, but there is little research on whether virtual reality could be used as a successful intervention for those with chronic pain. Virtual reality has few side effects, so it warrants consideration for the treatment of chronic pain. There is growing evidence that there is potential for virtual reality to produce desired results with patients having …

Characterization Of The Physical And Chemical Effect Of Membrane Disruption And Protein Inhibiting Treatments On E. Coli, Khadijah Wright

Honors Undergraduate Theses

The increase in antibacterial resistance has placed the issue of microbial multi-drug resistance on a global stage (Gurunathan, 2019). This issue poses a threat to human and animal health as well as to the environment (Aslam et al., 2018). It affects not only the efficacy of treatment but also how those treatments are conducted (Friedman, Temkin, & Carmeli, 2016). As a result of this ongoing threat, new treatments that have potent effects on bacteria are necessary. One scientific response to this issue has been the development of multifunctional nanoparticles (NPs)(H. Wang et al., 2018). NPs have the ability to be …

Exploring The Effects Service Dogs Have On Veterans With Ptsd, Shelby E. Reeves

Honors Undergraduate Theses

Post-Traumatic Stress Disorder (PTSD) is a mental illness resulting from exposure to a traumatic event. Symptoms of PTSD vary, but those affected commonly experience nightmares, flashbacks, hypervigilance, and trouble sleeping; they may also avoid people or situations that trigger traumatic memories. It is estimated that PTSD affects about 10-30% of all United States veterans. Additionally, traditional treatment methods have an average dropout rate of 25% among military personnel. Inadequate PTSD symptom management may lead to depression, anxiety, suicidality, isolation, unstable relationships, and substance misuse. The purpose of this review is to examine the current research concerning the use of service …