Medicine and Health Sciences Commons^™

The Colored Pill: A History Film Performance Exposing Race Based Medicines, Wanda Lakota

Electronic Theses and Dissertations

Of the 32 pharmaceuticals approved by the FDA in 2005, one medicine stood out. That medicine, BiDil®, was a heart failure medication that set a precedent for being the first approved race based drug for African Americans. Though BiDil®, was the first race specific medicine, racialized bodies have been used all throughout history to advance medical knowledge. The framework for race, history, and racialized drugs was so multi-tiered; it could not be conceptualized from a single perspective. For this reason, this study examines racialized medicine through performance, history, and discourse analysis.

The focus of this work aimed …

The Experiences Of Ncaa Student-Athletes With An Eating Disorder Or Disordered Eating, Rachel E. Taylor

Electronic Theses and Dissertations

The purpose of this study was to explore the experiences of student-athletes who had an eating disorder or disordered eating (ED/DE) while competing for the National Collegiate Athletic Association (NCAA). Integrating criticism and connoisseurship and critical evocative portraiture, four post-collegiate women who participated in cross country and track, who were either clinically diagnosed with an ED/DE or who self-diagnosed, participated in two interviews to describe their experiences with and the impact of ED/DE on their athletic pursuits, academic pursuits, as well as their relationships with coaches, teammates, and family. The analysis of these interviews showed the complexity of this topic. …

Human Genetics, Psychotropic Drugs, And Acts Of Violence, Selma Jolanda Eikelenboom-Schieveld

Electronic Theses and Dissertations

From the start of the use of psychoactive prescription medications in the 1950s, physicians reported paradoxical adverse reactions, ranging from newly developing depressions to an increase in existing mood disorders, and extremely violent and bizarre acts of suicide and homicide. In this research, it is hypothesized that the pharmacological properties of the prescribed drugs or the interaction between the drugs and the enzymes that are primarily responsible for their metabolism (cytochrome P450s) could cause these reactions. Given that acts of violence could be medication-induced, the role of the rate of drug metabolism is discussed. Genetic testing of certain CYP450s could …

Reliability Of Methods To Evaluate Sensitivity Caused By In-Office Bleaching Procedures, Ahmed Abuzinadah

Student Theses, Dissertations and Capstones

Objective: To evaluate and compare the reliability of different methods to measure sensitivity caused by in-office bleaching procedures.

Methodology: A convenience sample of 34 patients from the dental clinics at Nova Southeastern University participated in the study upon IRB approval, signing consent forms and complying the inclusion/exclusion criteria. All procedures were provided by the same operator (Dr. Abuzinadah) according to the manufacturer’s instructions using Opalescence® Boost® PF 40% (Ultradent, South Jordan, UT). No additional treatments were provided for desensitization. A visual analogue scale (VAS) was used to assess the level of sensitivity during the procedure, 1-hour, 24-hours, 48-hours, 1-week and …

Essential Notes On Pathophysiology For Advanced Practice Nurses, Alex Sargsyan

Open Educational Resources

This text is a compilation of lecture notes from pathophysiology courses I have taught over the last ten years. The goal of the text is to equip future advanced practice nurses with knowledge of pathophysiology for common diseases and disorders they may encounter in the primary care setting.

Effectiveness Of Physical Therapy Interventions In The Treatment Of Urinary Incontinence In Older Women: A Systematic Review, Ariana Gagliardi, Lauren Paretti, Kayla Stephani, Stephanie Oliverio

Student Research Poster Presentations 2020

Background: Urinary incontinence (UI) is a prevalent condition among older adults. While age and gender are risk factors, UI is not a natural part of female aging. By not seeking proper care, these individuals may be hindering their independence, opportunities to receive effective treatment, and their overall quality of life. Research shows a wide variety of physical therapy (PT) treatment options are available for UI.

Purpose: The purpose of this systematic review was to examine the effectiveness of various conservative PT interventions in treating stress, urge, and mixed UI in older women.

Methods: Two searches of the literature were performed …

The Role Of Behavioral Inhibition For Conversational Speech And Language Characteristics Of Preschool-Age Children Who Stutter, Victoria Tumanova, Carly Woods, Rachel Razza

Communication Sciences and Disorders - All Scholarship

No abstract provided.

Using Simulation To Improve Skills, Confidence, And Satisfaction Related To Diabetes Education, Greshin M. Markwell

Doctor of Nursing Practice Projects

Diabetes mellitus is the seventh leading cause of death in the U.S. and affects 30.3 million people (Centers for Disease Control and Prevention [CDC], 2019). Research suggests that patients often have a limited knowledge and insight into self-management of diabetes mellitus (DM). Acceptance of the disease, insufficient knowledge, and noncompliance are the examples of key factors that affect the progress of the disease. Nurses play a key role in the delivery of diabetes education which can improve compliance. Simulation can be used to improve the nursing skill sets for diabetes education. The purpose of this project was to implement evidence-based …

Minimizing Antipsychotic Medication Side Effects In Adults Diagnosed With Mental Illness Through Psychoeducation: An Evidence-Based Approach, Sarah A. Yao

Doctor of Nursing Practice Projects

Adherence to antipsychotic medication has demonstrated significant impact in decreasing symptom exacerbation among patients diagnosed with mental illness. Antipsychotic medications have several benefits including the management of psychotic and mood disorders; however, they could cause unwanted medication side effects with metabolic and cardiovascular risks. This issue is one of the commonly linked side effects resulting in nonadherence among mentally ill patients. The purpose of this project was to implement a psychoeducational intervention using the SIMPLE program to address metabolic and cardiovascular risks associated with antipsychotic medications among adult patients diagnosed with mental illness. A sample size of sixteen adult patients …

Occupational Therapy: The Supports And Barriers To Practice, Tammy Lane

Occupational Therapy Doctorate Capstone Projects

Background: The United States population is aging due to advances in healthcare and the aging of the “baby boomers generation” and the rate of aging is set to be the next public health challenge (Quarterman, 2017). Purpose: To address the unique nature of providing skilled therapy services in rural communities. To gain insight into the recruitment and retention of occupational therapists to rural communities. Theoretical Framework: The Model of Human Occupation (MOHO) (Kielhofner,2008) theory explains how occupations motivate participants in their environments supported by habits and roles in which they engage. Methods: Quantitative design using a descriptive method research approach …

Ace: A Recipe For Occupational Competence, Brittany J. Miller

Occupational Therapy Doctorate Capstone Projects

Adverse childhood experiences are increasing in society and the lack of knowledge surrounding the condition from the adults who frequently interact with them is concerning. This concern lays the foundation for the development of a targeted approach to pediatric intervention by occupational therapists. The problem this capstone project addresses is expanding the understanding of how adverse childhood experiences mirror other common conditions as well as the need for more competent and confident occupational therapists in identifying and treating children with adverse childhood experiences.

Lincoln County Community Paramedicine Data Collection Initiative [Infographic], Evelyn Ali Bs, Katie Rosingana Ba, Karen Pearson Mlis, Ma

Substance Use Research & Evaluation

No abstract provided.

Project Support You: Addressing The Opioid Epidemic Through Community Collaboration And Education. Tri-County Mental Health [Infographic], Mary Lindsey Smith Phd, Evelyn Ali Bs, Rachel M. Gallo Mph, Tyler Egeland Ba

Substance Use Research & Evaluation

No abstract provided.

An Exploration Of Financial Management Programming For Residents In One Homeless Shelter: A Qualitative Institutional Case Study, Amy M. Heiser

Occupational Therapy Doctorate Capstone Projects

Introduction: Homelessness affects the economy, societies, and individuals’ physical, mental, and emotional well-being. Occupational therapy is a holistic profession that works with all populations across the lifespan. Financial management is a life skill that many Americans struggle with. Evidence on financial management skill development within homeless shelters and occupational therapy is sparse. Occupational justice is a theoretical framework that supports the right for residents in a homeless shelter to have direct interventions toward skill development, such as education in financial management. Methods: This institutional case study explored a homeless shelter to gain knowledge of real-life program phenomena, with focus on …

The Value Driven Pharmacist: Basics Of Access, Cost, And Quality 2nd Edition, Carriann Smith, Annette Mcfarland, Chad Knoderer, Joseph Jordan, Trish Devine, Jessica Wilhoite

Butler University Books

No abstract provided.

Integrative Qtl Analysis Of Gene Expression And Chromatin Accessibility Identifies Multi-Tissue Patterns Of Genetic Regulation., Gregory R Keele, Bryan C Quach, Jennifer W Israel, Grace A Chappell, Lauren Lewis, Alexias Safi, Jeremy M Simon, Paul Cotney, Gregory E Crawford, William Valdar, Ivan Rusyn, Terrence S Furey

Faculty Research 2020

Gene transcription profiles across tissues are largely defined by the activity of regulatory elements, most of which correspond to regions of accessible chromatin. Regulatory element activity is in turn modulated by genetic variation, resulting in variable transcription rates across individuals. The interplay of these factors, however, is poorly understood. Here we characterize expression and chromatin state dynamics across three tissues-liver, lung, and kidney-in 47 strains of the Collaborative Cross (CC) mouse population, examining the regulation of these dynamics by expression quantitative trait loci (eQTL) and chromatin QTL (cQTL). QTL whose allelic effects were consistent across tissues were detected for 1,101 …

The Effect Of Proton Pump Inhibitors On Normal Gastrointestinal Flora Leading To Weight Change, Emi L. Binstock

Physician Assistant Scholarly Project Posters

The goal of this literature review was to determine what effects proton pump inhibitors (PPIs) have on the normal gastrointestinal (GI) flora and how that may lead to weight loss or weight gain. A literature search was performed using the database PubMed. Only articles from the last ten years (2009-2019) were included in this review. Keywords used in the search are listed below. After exclusion criteria was applied, 30 articles were relevant and used in this review. Five themes were identified in the literature review. An investigation of normal GI flora associated with weight loss and weight gain identified a …

Efficacy Of Bariatric Surgery Compared To Non-Surgical Treatments For Morbid Obesity, Erica Donovan

Physician Assistant Scholarly Project Posters

The purpose of this research is to show the efficacy of Roux-en-Y gastric bypass and sleeve gastrectomy as compared to traditional diet and exercise models. Finding ways to combat morbid obesity has resulted in invasive surgical techniques because traditional diets and exercise work infrequently and often fail. Systematic reviews, metaanalysis, randomized controlled trials and retrospective studies were found using the data base of CINAHL, SportsDiscus, PsycInfo, Embase, and PubMed. All of the studies were published no later than 2014 and used human adult subjects ages 19-65. The studies reviewed show that bariatric surgery is a safe and effective obesity treatment …

Comparison Of Buprenorphine-Naloxone And Buprenorphine Monotherapy In Opioid Dependent Pregnant Women, Ellie Gillund

Physician Assistant Scholarly Project Posters

•The purpose of this literature review is to compare the use of buprenorphine-naloxone combination therapy to buprenorphine monotherapy as medication assisted therapy (MAT) for opioid dependent pregnant women.

•Outcomes compared in this study include maternal and neonatal safety, neonatal abstinence syndrome, and peripartum pain management.

•This review included electronic search databases: PubMed, Clinical Key, and Cochrane Library from September 1, 2019 to March 1, 2020. The search included randomized control trials, systematic reviews, and meta-analysis. Sources excluded included those published >25 years ago, those with poor study design, and those with primary focus on methadone.

•Current research shows evidence to …

Surgical Innovations For Gerd: Comparing Outcomes Of Magnetic Sphincter Augmentation And Nissen Fundoplication, Steffani N. Johnston Mack

Physician Assistant Scholarly Project Posters

Gastroesophageal reflux disease (GERD) is a common chronic upper gastrointestinal disease with both objective and subjective components. While most cases of GERD are uncomplicated and can be managed with oral medication, refractory cases require surgical intervention. The purpose of this study is to compare the efficacy of GERD’s gold standard surgical technique, the Nissen fundoplication, with a new surgical technique, magnetic sphincter augmentation.

Antibiotic Efficacy In Lower Back Pain, Alexander M. Lee

Physician Assistant Scholarly Project Posters

Chronic lower back pain affects approximately eight percent of the American population, yet no treatment has been agreed upon universally. Studies suggest that between 20-30 percent of lower back pain cases are caused by a low-virulence bacterial infection of an intervertebral disc. • This scholarly project investigated: In patients with chronic lower back pain and Modic changes after disc herniation, what is the effect of antibiotic therapy on reducing pain symptoms compared to placebo. • The literature review used the following electronic databases: ClinicalKey, Cochrane Library, Embase, and PubMed. Keywords and mesh terms refined searches to the most recent and …

An Analysis Of The Incidence And Severity Of Drug-Drug Interactions Between Prescribed Pharmaceuticals And Cannabinoids, Jennifer Mcrae

Physician Assistant Scholarly Project Posters

Identify the incidence and severity of drug-drug interactions between commonly prescribed medications and cannabinoids • Medications that are substrates for CYP2C19, CYP2C9 and CYP1A2 are at the greatest risk of interaction with concomitant use of phytocannabinoids or synthetic cannabinoids • Caution is recommended with medications metabolized via UGT or CES1, however information is currently limited and further research is necessary • Lack of universal standards for laboratory testing of cannabinoid products call into question the legitimacy of reported results in currently reported research as the contents of many cannabinoid products are inaccurately labeled

Analysis Of Tech-Based And Telemental Health Approaches Within The Adolescent And Young Adult Populations Of Rural America, Audrey K. Smeenk

Physician Assistant Scholarly Project Posters

The incidences of depression and anxiety among adolescent and young adult populations are intensifying, and resources remain limited for the management of these diseases within rural America.

• Evaluation on different interventions was completed to assess ease of access, efficacy, and patient adherence with the hope to decrease incidence of disease and increase availability of resources to rural areas.

• Based on the current completed research, there is a predominance of evidence that has shown moderate statistical data and promising outcomes from tech-based mobile applications and telemental health. Statistical evidence supports that technological based interventions are a potential treatment option …

Hyperbaric Oxygen Therapy For The Treatment Of Traumatic Brain Injuries, Jordan A. Wiedmann

Physician Assistant Scholarly Project Posters

This research and systematic literature review evaluates the safety and efficacy of Hyperbaric oxygen therapy (HBOT) to improve treatment outcomes in traumatic brain injuries (TBIs). This review included the search of PubMed, Cochrane Review, Clinical Key, and DynaMed. The search included randomized control trials, systematic reviews, and meta-analyses published in the last 20 years.

• Several studies show evidence to support the use of HBOT in TBIs, however the majority of research suggests overall insufficient evidence on the topic. Several studies also address the concern for safety and side effects, as individuals are exposed to increased pressures for long lengths …

Early Intervention: Addressing Opioid Use Disorder With Emergency Department Initiated Buprenorphine Therapy, Dustin Voss

Physician Assistant Scholarly Project Posters

An evaluation of opioid use disorder (OUD) as defined by the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) diagnostic criteria.

• The use of buprenorphine in the process of induction, its efficacy for the management of OUD, and barriers to its initiation.

• Outcomes of the initiation of office-based buprenorphine treatment are compared to emergency departmentinitiated buprenorphine treatment for the management of OUD.

• Results revealed that buprenorphine is effective in treating OUD when appropriate induction and maintenance doses are implemented. However, there continue to be barriers in prescribing that have limited access to the medication.

• Office-based buprenorphine …

"Pliable And Easily Shaped": History, Harms, And Regulations Of Plastic In The United States, Krista Decima Smithers

Online Theses and Dissertations

The majority of plastic exists in a linear economy, wherein a product is developed with raw materials, used, and then discarded. Because there are many applications for plastic in today’s society unparalleled by alternative materials, removing all or most plastic use from daily life in the United States is unrealistic. Nevertheless, eliminating single-use plastics and improving recycling are reasonably attainable goals.

This thesis offers a detailed discussion of the origins of plastic, including its discovery, initial applications, and growth in the United States. Against this backdrop, this thesis then examines how various nonhuman animal species and ecosystems have been negatively …

Relationship Between Formative Test Results And Final Exam Performance In First Year Medical School Course, Grace Owens

Scholarship in Medicine - All Papers

Objective: The purpose of the study was to evaluate whether formative testing from iRAT and MCQ data was predictive of final exam scores for the Staying Alive course at WSU BSOM. Methods: Data was collected from two consecutive classes of first-year medical students (n=234). Data included students’ formative quiz scores (iRAT), formative exam scores (MCQ), final exam scores (NBME), race, and gender. Three regression models were created to analyze the relationship between formative and final scores. Results: The average iRAT score was not a significant predictor of NBME score. 53-56% of the variability in NBME score was attributed to iRAT, …

Ancient Wisdom And Future Medicine: A Defense Of The Science Of Ayurveda, Michael Eatmon

Master of Liberal Studies Theses

A growing number of people turn to Ayurveda as a complement or an alternative to conventional Western medicine. What are they turning to—a genuine medical science or a patent pseudoscience? This paper claims that modern Ayurvedic medicine is a genuine science with a promising future.

2020 Children's Story Cards, Tsos

TSOS Interview Gallery

Arif: "I like being in school again."

Norina: "We laugh a lot but I also worry."

Nooda: "I came on a boat. It was a big boat!"

Madina: "I just want to live in a safe place..."

Shurangez: "Sometimes we didn't feel safe at school."

Alex: "I'm from Nigeria. Coming to Italy was very difficult-very, very difficult, a real struggle."

Danial: "I want to be a useful person and follow my dreams."

Firoz: "I am 13 years old and I am worried about my family."

Ali: "Ali lived in Afghanistan. One day while walking to school a bomb exploded near …

Dual Substance Use Of Electronic Cigarettes And Alcohol, Tanner J. Wetzel, Todd A. Wyatt

Journal Articles: Environmental, Agricultural & Occupational Health

Electronic cigarettes (ECs) are a modern nicotine delivery system that rapidly grew in widespread use, particularly in younger populations. Given the long history of the comorbidity of alcohol and nicotine use, the rising prevalence of ECs raises the question as to their role in the consumption of alcohol. Of the numerous models of ECs available, JUUL is the most popular. This narrative review aims to determine current trends in literature regarding the relationship between EC and alcohol dual use, as well as hypothesize potential pathogenic tissue damage and summarize areas for future study, including second-hand vapor exposure and calling for …